Frontiers in Medicine最新文献

{"title":"Editorial: Seeing is believing: cutting-edge technologies transforming ophthalmology.","authors":"Miguel Angel Ariza-Gracia, Vijayavenkataraman Sanjairaj, Philippe Büchler","doi":"10.3389/fmed.2025.1569161","DOIUrl":"https://doi.org/10.3389/fmed.2025.1569161","url":null,"abstract":"","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1569161"},"PeriodicalIF":3.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facilitators and barriers to chronic non-communicable disease management under family doctor contracting services in China.","authors":"Rui Jiang, Yuze Xin, Shuangjie Peng, Yuhan Zhou, Xinyi Zhang, Yu Shi, Guangming Chang, Min Yang, Lvzhuang Huang, Lingling Xu, Xinrui Wei, Yongchen Wang","doi":"10.3389/fmed.2025.1506016","DOIUrl":"10.3389/fmed.2025.1506016","url":null,"abstract":"<p><strong>Background: </strong>Chronic non-communicable diseases (NCDs) pose a significant health burden in China exacerbated by population aging and rapid urbanization. The Family Doctor Contracting Service has been implemented in China as a primary health care approach to improve NCD management and overall health outcomes. This study aims to identify factors associated with implementing chronic NCD management under the FDCS in the Chinese primary health care system.</p><p><strong>Methods: </strong>This qualitative study was conducted in 4 purposively selected cities in China. Health administrators from the local health commission, staff members from local primary health care facilities, and community-dwelling individuals with NCDs were recruited using purposive and snowball sampling. The reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) framework was adopted to inform our interview guides and data collection and analysis. Themes regarding barriers and facilitators were generated using deductive and inductive approaches.</p><p><strong>Results: </strong>A total of 140 participants were interviewed 82 (58.6%) were female and the mean (SD) age was 51.0 (13.68) years. Significant barriers included low health literacy levels, limited awareness about NCD, insufficient healthcare professionals and medical resources, poor publicity and regulation, limited multisectoral collaboration, and inadequate audit and feedback systems. Facilitators included affordable and convenient primary health services, recognition of the indispensable benefits of NCD management, good patient-physician bonds, and the high priority given by local governments.</p><p><strong>Conclusion: </strong>This qualitative study identified significant facilitators and barriers to the implementation of NCD management under the FDCS at the primary care level. These insights can contribute to better NCD prevention and management implementation in the Chinese primary health care system.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1506016"},"PeriodicalIF":3.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical association of body symptoms and primary dysmenorrhea among young and middle-aged women: an observational study.","authors":"Tzyy-Guey Tseng, Che-Yen Kuan, Yun-Ping Lo, Yun-Shiuan Chuang, Chun-Ying Lee, Yi-Ting Lin, Ing-Luen Shyu, Ming-Tsang Wu, Chi-Jung Tai","doi":"10.3389/fmed.2025.1529470","DOIUrl":"10.3389/fmed.2025.1529470","url":null,"abstract":"<p><strong>Background: </strong>The mechanism of primary dysmenorrhea remains unraveled. Body symptoms not related to menstrual cycle may indicate the potential mechanism of primary dysmenorrhea, albeit the association has not been proven. Furthermore, we hypothesize that the cumulative burden of these symptoms may influence the incidence of primary dysmenorrhea. Therefore, we aim to design a study to identify bodily symptoms potentially related to primary dysmenorrhea and test the hypothesis in understanding and managing primary dysmenorrhea.</p><p><strong>Methods: </strong>A total of 3,140 female participants aged 30-50 years were enrolled from the Taiwan Biobank. Stepwise logistic regression was used to select potential body symptoms associated with primary dysmenorrhea from a training dataset. Selected body symptoms were validated in a test dataset. Female participants without dysmenorrhea in the baseline survey were divided into two groups (with and without body symptoms) in a baseline survey. Cox regression and Kaplan-Meier survival analyses were used to evaluate the risk of incident dysmenorrhea.</p><p><strong>Results: </strong>Women with body symptoms such as cold extremities (adjusted odds ratio [AdjOR], 1.53, 95% confidence interval [CI], 1.12-2.21), dull abdominal pain (AdjOR, 1.45, 95% CI, 1.03-2.04), and edema (AdjOR, 1.43, 95% CI, 1.02-1.99) were significantly associated with dysmenorrhea. Women with the three body symptoms had a significantly higher risk of dysmenorrhea (adjusted hazard ratio, 2.74, 95%CI, 1.18-6.31; log-rank test, <i>p</i> = 0.0017) than those without body symptoms. Trend analysis showed that the risk of dysmenorrhea increased with the number of body symptoms (<i>p</i>-trend = 0.025).</p><p><strong>Conclusion: </strong>This study identified cold extremities, dull abdominal pain, and edema as predictors of primary dysmenorrhea, with their accumulation associated with a higher risk of developing dysmenorrhea. We propose that further research explore pharmacological and non-pharmacological interventions targeting these symptoms, as they may provide long-term benefits in the management of primary dysmenorrhea.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1529470"},"PeriodicalIF":3.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11930807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, attitudes, and practices of gastric cancer patients toward nutritional therapy.","authors":"Hui Yu, Ling Li, Jing Gu, Jing Wang, Hui Su, Hui Lu, Yuqing Zhou, Jingfang Xia, Yongping Xu, Danhua Liang, Yuling Yang, Ying Chen","doi":"10.3389/fmed.2025.1433849","DOIUrl":"10.3389/fmed.2025.1433849","url":null,"abstract":"<p><strong>Background: </strong>To investigate the knowledge, attitude, and practice (KAP) of patients with gastric cancer (GC) toward nutritional therapy.</p><p><strong>Methods: </strong>This cross-sectional study was conducted from January to March 2024 at the Affiliated Hospital of Jiangnan University (Wuxi, China) and enrolled patients with GC. Questionnaires (Cronbach's <i>α</i> = 0.923) were used to collect data on demographics and KAP dimensions. Scores >75% were considered good. Multivariable analyses were performed to examine the factors associated with KAP. A structural equation modeling (SEM) analysis was performed to examine the relationships among KAP dimensions.</p><p><strong>Results: </strong>The analysis included 486 valid questionnaires. The median knowledge, attitude, and practice scores were 6.0 (0-16; 37.5%), 26.0 (7-35; 74.3%), and 28.7 (8-40; 71.7%) indicating poor KAP. Only agricultural, forestry, animal husbandry, fishery, and water conservancy production personnel (OR = 0.09, 95%CI: 0.02-0.49, <i>p</i> = 0.006) were independently associated with knowledge. Knowledge (OR = 1.11, 95%CI: 1.05-1.18, <i>p</i> < 0.001) and a monthly income of 10,000-20,000 (OR = 3.85, 95%CI: 1.23-12.06, <i>p</i> = 0.021) were independently associated with attitude. Knowledge (OR = 1.22, 95%CI: 1.15-1.30, <i>p</i> < 0.001), attitude (OR = 1.21, 95%CI: 1.11-1.32, <i>p</i> < 0.001), personnel other than leading cadres of state organs and enterprises (all OR < 1 and all <i>p</i> < 0.05), and a monthly income of 10,000-20,000 yuan (OR = 3.02, 95%CI: 1.15-7.96, <i>p</i> = 0.025) were independently associated with practice. Knowledge had a direct positive influence on attitude (<i>β</i> = 0.350, <i>p</i> < 0.001) and practice (<i>β</i> = 0.460, <i>p</i> < 0.001) and an indirect positive influence on practice (<i>β</i> = 0.146, <i>p</i> < 0.001). Attitude had a direct positive influence on practice (<i>β</i> = 0.417, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Patients with GC in Wuxi partly had poor KAP toward nutritional support.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1433849"},"PeriodicalIF":3.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning-based spirometry reference values for the Iranian population: a cross-sectional study from the Shahedieh PERSIAN cohort.","authors":"Mohammad Sadegh Loeloe, Reyhane Sefidkar, Seyyed Mohammad Tabatabaei, Amir Houshang Mehrparvar, Sara Jambarsang","doi":"10.3389/fmed.2025.1480931","DOIUrl":"10.3389/fmed.2025.1480931","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to determine spirometric norm values for the healthy Iranian adult population and compare them with established norm equations, specifically the GLI-Caucasian and Iranian equations.</p><p><strong>Methods: </strong>During the recruitment phase of the Shahedieh Prospective Epidemiological Research Studies in Iran (PERSIAN) in 2016, spirometric parameters of 998 participants were obtained. KNN regression was used to extract reference values for spirometric parameters FEV₁, FVC, FEV₁/FVC, and FEF_25-75%, considering height and age as features. The performance of KNN regression was compared with conventional models used in previous studies, such as the multiple linear regression (MLR) model and the Lambda-Mu-Sigma (LMS) model. The predicted values were compared with those obtained from the GLI-Caucasian and Iranian equations. The validation criterion was the mean squared error (MSE) based on 5-fold cross-validation.</p><p><strong>Results: </strong>This study included 473 female participants and 525 male participants. KNN regression provided more accurate predictions for four spirometric parameters than MLR and LMS. The MSE for predicting FVC in female participants was 0.159, 0.169, and 0.165 in KNN regression, MLR, and LMS, respectively. The predictions of the present study were closer to the actual values of the reference population for four indicators compared to the prediction values using two sets of reference equations. The MSE of predicted FVC for female participants was 0.159 in the present study, which was less than the Iranian (MSE = 0.344) and GLI-Caucasian (MSE = 0.397) equations.</p><p><strong>Conclusion: </strong>Using a flexible machine learning approach, this study established spirometry reference values specifically for the Iranian population. Recognizing that spirometry reference values vary among different populations, the Excel calculator developed in this research can be a valuable tool in healthcare centers for assessing lung function in Iranian adults.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1480931"},"PeriodicalIF":3.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing Interprofessional Education and Collaborative Practice: outcomes of the AFREhealth-FAIMER Student Elective Exchange Program in Health Professions Education in Africa.","authors":"Faith Nawagi, Rashmi Vyas, Elsie Kiguli Malwadde, Shiyao Yuan, Deborah Bedoll, Prisca Olabisi Adejumo, Rory Phimister, Julie Drendall, Justin Seeling, Fatima Suleman","doi":"10.3389/fmed.2025.1516156","DOIUrl":"10.3389/fmed.2025.1516156","url":null,"abstract":"<p><strong>Background: </strong>While some African health professions institutions have advanced in integrating Interprofessional Education and Collaborative Practice (IPECP) into their curricula, many still struggle with traditional, siloed training. To address this gap, the African Forum for Research and Education in Health (AFREhealth), partnering with FAIMER, a division of Intealth, developed the AFREhealth-FAIMER IPECP Student Elective Exchange Program (IPECP Program). This study assessed the IPECP competencies of participating students and gathered stakeholder perspectives on the IPECP Program.</p><p><strong>Methods: </strong>The 2018 revised Interprofessional Collaborative Competency Attainment Scale (ICCAS), containing 21 items, was used to assess student participants' IPECP competencies before and after participating in the IPECP Program. Paired sample T-tests were run to examine if there was a significant improvement in IPECP competencies after students participated in the program, on both the total and item score levels. The study also administered online surveys to collect feedback from faculty and managers of the IPECP Program on its design, implementation, benefits, and challenges.</p><p><strong>Results: </strong>Students reported a significant improvement in IPECP competencies after participating in the program, with the mean ICCAS total score rising from 79.27 (±12.24) pre-training to 85.63 (±8.75) post-training (<i>t</i>(179) = 7.48, <i>p</i> < 0.005). All faculty participants (100%, <i>n</i> = 18) indicated that country-specific case studies facilitated teaching IPECP skills through virtual delivery. Additionally, 6 out of 18 program managers noted that this program marked their institution's first engagement in virtual IPECP electives. All faculty (<i>n</i> = 18) and managers (<i>n</i> = 10) who responded to the survey thought the IPECP program enhanced regional collaborations and global exposure and equipped the students with cross-country IPECP skills. Internet connectivity was a cross-cutting challenge among faculty and managers given the virtual nature of the program.</p><p><strong>Discussion and conclusions: </strong>The student participants of the IPECP Program self-reported enhanced IPECP competencies, fostering an understanding of the various population health issues in multiple African countries. The findings suggest that faculty-guided, country-specific case studies may offer a viable strategy for implementing IPECP during international electives using a virtual mode of delivery.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1516156"},"PeriodicalIF":3.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strengthening nursing knowledge and skills in perioperative cleft care: a focused training approach in Nigeria's surgical healthcare plan.","authors":"Olubunmi Aiyedun Lawal, Ngozika Opara, Chisom Rachel Udeigwe-Okeke, Aderonke Omoyeni Obisesan, Justina Seyi-Olajide, Oti Nimi Aria, Mohammed Adam Sheikh Abdullahi, Nkeiruka Obi, Emmanuel A Ameh","doi":"10.3389/fmed.2025.1502456","DOIUrl":"10.3389/fmed.2025.1502456","url":null,"abstract":"<p><strong>Background: </strong>Safe perioperative nursing care is crucial to improving outcomes of surgical care. This is a report on the pilot implementation of a nursing training programme aimed at strengthening safe perioperative nursing care in Nigeria, aligning with the nation's strategic framework for surgical, obstetric, anaesthesia, and nursing plan. The aim of this report is to highlight the need to incorporate perioperative nursing training into efforts to scale up access to surgical care in low resource settings.</p><p><strong>Methods: </strong>The Nursing Care Saves Lives (NCSL) training programme which was designed for training in perioperative nursing of cleft lip and palate patients, was adapted for perioperative nursing training. A 5-day intensive training was deployed, involving lectures, hands-on activities, simulations, and group problem-solving exercises. Pre- and post-training surveys were administered, and participant feedback and 3-months follow-up assessments obtained. The data has been analysed using descriptive statistics.</p><p><strong>Results: </strong>Twenty-six participants who were nurses involved in perioperative care, from both public and private hospitals, completed the training. Pre-training evaluation scores ranged from 23 to 72% (median 68%), increasing significantly to 61-98% (median 76%) post-training (<i>p</i> = 0.0001). Participants rated all training contents as useful, with high satisfaction in neonatal resuscitation and basic life support skills. Infection prevention and control, helping babies breathe, and effective communication were identified as key learnings. Recommendations for future training included facilitation skills, nutrition, and research. Although 10 (40%) participants organised step down trainings, limited funding and training materials were key barriers to step down.</p><p><strong>Conclusion: </strong>The NCSL training programme has the potential for promoting and strengthening safe perioperative nursing care. Strategic efforts are needed to scale up and expand access to this training within the wider perioperative nursing community, to enhance patient safety and surgical outcomes in the setting.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1502456"},"PeriodicalIF":3.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological and clinical characteristics of COVID-19 mortality: a retrospective study.","authors":"Yaohua Hu, You Lu, Jiagui Dong, Delin Xia, Jin Li, Hong Wang, Min Rao, Chenxing Wang, Wanning Tong","doi":"10.3389/fmed.2025.1464274","DOIUrl":"10.3389/fmed.2025.1464274","url":null,"abstract":"<p><strong>Background: </strong>The global impact of SARS-CoV-2 and its associated coronavirus disease (COVID-19) has necessitated urgent characterization of prognostic biomarkers. This study aimed to delineate the epidemiological and clinical predictors of mortality among hospitalized COVID-19 patients.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted on 123 patients with laboratory-confirmed COVID-19 admitted to Huoshenshan Hospital (Wuhan, China) from 1 February 2020 to 30 April 2020. Kaplan-Meier curve and multivariate Cox regression were used to assess the independent factors with survival time. Statistical significance was set at a <i>p</i>-value of <0.05.</p><p><strong>Results: </strong>The cohort exhibited a mortality rate of 49.6% (61/123), with the critical clinical type (HR = 7.970, <i>p</i> = 0.009), leukocytosis (HR = 3.408, <i>p</i> = 0.006), and lymphopenia (HR = 0.817, <i>p</i> = 0.038) emerging as independent predictors of reduced survival. Critical-type patients demonstrated significantly elevated inflammatory markers (neutrophils: 10.41 ± 6.23 × 10⁹/L; CRP: 104.47 ± 29.18 mg/L) and coagulopathy (D-dimer: 5.21 ± 2.34 μg/ml) compared to non-critical cases. Deceased patients exhibited pronounced metabolic derangements, including hyperglycemia (9.81 ± 2.07 mmol/L) and hepatic dysfunction (ALP: 174.03 ± 30.13 U/L).</p><p><strong>Conclusion: </strong>We revealed the epidemiological and clinical features of different clinical types of SARS-CoV-2 as summarized in this paper. We found that critical type, leukocyte, and lymphocyte are risk factors that affect survival time, which could be an early and helpful marker to improve management of COVID-19 patients.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1464274"},"PeriodicalIF":3.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11930819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skin-lesion segmentation using boundary-aware segmentation network and classification based on a mixture of convolutional and transformer neural networks.","authors":"Javaria Amin, Marium Azhar, Habiba Arshad, Amad Zafar, Seong-Han Kim","doi":"10.3389/fmed.2025.1524146","DOIUrl":"10.3389/fmed.2025.1524146","url":null,"abstract":"<p><strong>Background: </strong>Skin cancer is one of the most prevalent cancers worldwide. In the clinical domain, skin lesions such as melanoma detection are still a challenge due to occlusions, poor contrast, poor image quality, and similarities between skin lesions. Deep-/machine-learning methods are used for the early, accurate, and efficient detection of skin lesions. Therefore, we propose a boundary-aware segmentation network (BASNet) model comprising prediction and residual refinement modules.</p><p><strong>Materials and methods: </strong>The prediction module works like a U-Net and is densely supervised by an encoder and decoder. A hybrid loss function is used, which has the potential to help in the clinical domain of dermatology. BASNet handles these challenges by providing robust outcomes, even in suboptimal imaging environments. This leads to accurate early diagnosis, improved treatment outcomes, and efficient clinical workflows. We further propose a compact convolutional transformer model (CCTM) based on convolution and transformers for classification. This was designed on a selected number of layers and hyperparameters having two convolutions, two transformers, 64 projection dimensions, tokenizer, position embedding, sequence pooling, MLP, 64 batch size, two heads, 0.1 stochastic depth, 0.001 learning rate, 0.0001 weight decay, and 100 epochs.</p><p><strong>Results: </strong>The CCTM model was evaluated on six skin-lesion datasets, namely MED-NODE, PH2, ISIC-2019, ISIC-2020, HAM10000, and DermNet datasets, achieving over 98% accuracy.</p><p><strong>Conclusion: </strong>The proposed model holds significant potential in the clinical domain. Its ability to combine local feature extraction and global context understanding makes it ideal for tasks like medical image analysis and disease diagnosis.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1524146"},"PeriodicalIF":3.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: SVF after chemoradiotherapy for cervical cancer diagnosed by non-contact hysteroscopic technique.","authors":"Xuemei Sun, Yinghua He, Xuedong Yang, Yu Wu, Yanhuan Yang, Yanping Wang, Xiuhua Fan","doi":"10.3389/fmed.2025.1511052","DOIUrl":"10.3389/fmed.2025.1511052","url":null,"abstract":"<p><p>Sigmoidovaginal fistula (SVF) is an extremely distressing and complex condition that significantly impacts a patient's quality of life. The successful management of SVF relies on accurately identifying the fistula's location and tract. However, preoperative localization can be challenging in certain cases. In this report, we describe a rare complication in a patient with stage IVA cervical cancer who developed SVF after concurrent chemoradiotherapy. Conventional diagnostic methods, including electron colonoscopy, methylene blue testing, and fistulography, were unable to locate the fistula. As an alternative, we used a non-contact hysteroscopic technique, which successfully identified the location, size, and number of fistulas. This method is particularly effective for patients with SVF, especially in postmenopausal women with narrowed or adherent vaginal tracts, women with intact hymen, and those with complex, high-grade vaginal fistulas resulting from cancer treatment with chemoradiotherapy.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1511052"},"PeriodicalIF":3.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11930810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}