{"title":"病例报告:半乳糖不良链球菌。乳腺癌放化疗后血液感染中的泌乳障碍。","authors":"Chongmei Tian, Su Dong, Zhixin You, Yaping Zhao, Hongfeng Xu, Jingbai Chen, Yuejuan Fang","doi":"10.3389/fmed.2025.1572998","DOIUrl":null,"url":null,"abstract":"<p><p>Bloodstream infections are life-threatening conditions in patients with breast cancer, especially among older individuals. Although the most common risk factor in these patients with tumors is the use of severe neutropenia secondary to myelosuppressive chemotherapy and radiotherapy, other factors are possibly associated with the invasive pathogenicity of microorganisms, including <i>Streptococcus dysgalactiae</i>. <i>Streptococcus dysgalactiae</i> ssp. <i>dysgalactiae (SDSD)</i> has been considered both an environmental pathogen and a contagious pathogen. However, there have been few reports of bloodstream infections with SDSD in patients with breast cancer after radiotherapy and chemotherapy. In this study, we report an interesting case of bloodstream infection caused by SDSD in an older patient with breast cancer after radiotherapy and chemotherapy. A 60-year-old Chinese woman had a history of breast cancer for 2 years. She developed chills and fever after puncturing blood blisters in the mouth, accompanied by fatigue and poor appetite. After 6 days of antimicrobial therapy, the patient showed gradual recovery. Bloodstream infections with SDSD in patients with breast cancer are rare. Therefore, accurate diagnosis and timely treatment can be lifesaving.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1572998"},"PeriodicalIF":3.1000,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162340/pdf/","citationCount":"0","resultStr":"{\"title\":\"Case Report: <i>Streptococcus dysgalactiae</i> ssp. <i>dysgalactiae</i> bloodstream infections in patients with breast cancer after radiotherapy and chemotherapy.\",\"authors\":\"Chongmei Tian, Su Dong, Zhixin You, Yaping Zhao, Hongfeng Xu, Jingbai Chen, Yuejuan Fang\",\"doi\":\"10.3389/fmed.2025.1572998\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Bloodstream infections are life-threatening conditions in patients with breast cancer, especially among older individuals. Although the most common risk factor in these patients with tumors is the use of severe neutropenia secondary to myelosuppressive chemotherapy and radiotherapy, other factors are possibly associated with the invasive pathogenicity of microorganisms, including <i>Streptococcus dysgalactiae</i>. <i>Streptococcus dysgalactiae</i> ssp. <i>dysgalactiae (SDSD)</i> has been considered both an environmental pathogen and a contagious pathogen. However, there have been few reports of bloodstream infections with SDSD in patients with breast cancer after radiotherapy and chemotherapy. In this study, we report an interesting case of bloodstream infection caused by SDSD in an older patient with breast cancer after radiotherapy and chemotherapy. A 60-year-old Chinese woman had a history of breast cancer for 2 years. She developed chills and fever after puncturing blood blisters in the mouth, accompanied by fatigue and poor appetite. After 6 days of antimicrobial therapy, the patient showed gradual recovery. Bloodstream infections with SDSD in patients with breast cancer are rare. Therefore, accurate diagnosis and timely treatment can be lifesaving.</p>\",\"PeriodicalId\":12488,\"journal\":{\"name\":\"Frontiers in Medicine\",\"volume\":\"12 \",\"pages\":\"1572998\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162340/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3389/fmed.2025.1572998\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fmed.2025.1572998","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Case Report: Streptococcus dysgalactiae ssp. dysgalactiae bloodstream infections in patients with breast cancer after radiotherapy and chemotherapy.
Bloodstream infections are life-threatening conditions in patients with breast cancer, especially among older individuals. Although the most common risk factor in these patients with tumors is the use of severe neutropenia secondary to myelosuppressive chemotherapy and radiotherapy, other factors are possibly associated with the invasive pathogenicity of microorganisms, including Streptococcus dysgalactiae. Streptococcus dysgalactiae ssp. dysgalactiae (SDSD) has been considered both an environmental pathogen and a contagious pathogen. However, there have been few reports of bloodstream infections with SDSD in patients with breast cancer after radiotherapy and chemotherapy. In this study, we report an interesting case of bloodstream infection caused by SDSD in an older patient with breast cancer after radiotherapy and chemotherapy. A 60-year-old Chinese woman had a history of breast cancer for 2 years. She developed chills and fever after puncturing blood blisters in the mouth, accompanied by fatigue and poor appetite. After 6 days of antimicrobial therapy, the patient showed gradual recovery. Bloodstream infections with SDSD in patients with breast cancer are rare. Therefore, accurate diagnosis and timely treatment can be lifesaving.
期刊介绍:
Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate
- the use of patient-reported outcomes under real world conditions
- the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines
- the scientific bases for guidelines and decisions from regulatory authorities
- access to medicinal products and medical devices worldwide
- addressing the grand health challenges around the world