{"title":"高度近视相关性外斜视对单侧退行切除手术剂量反应的影响:一项回顾性研究。","authors":"Chao Li, ZhiYin Lou, Fan Yang","doi":"10.3389/fmed.2025.1588698","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To investigate the impact of high myopia on the surgical dose-response in unilateral recession and resection (R&R) surgery for exotropia.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 101 Chinese patients who underwent unilateral R&R surgery for concomitant exotropia between June 2021 and June 2024. Patients were divided into two groups based on axial length: those with high myopia (<i>n</i> = 38) and those without high myopia (<i>n</i> = 63). Surgical doses for lateral rectus (LR) recession and medial rectus (MR) resection were compared between the groups. Preoperative and postoperative deviations were measured, and statistical analyses were performed to assess the relationship between surgical dose, axial length (AL), and other clinical variables.</p><p><strong>Results: </strong>Age, duration of exotropia, and AL differed significantly between the groups, but other baseline characteristics were comparable. The LR recession dose did not differ significantly between the high myopia group (6.40 ± 1.11 mm) and the non-high myopia group (6.74 ± 1.00 mm, <i>p</i> > 0.05). However, the MR resection dose was significantly lower in the high myopia group (5.77 ± 1.02 mm) compared to the non-high myopia group (6.32 ± 0.92 mm, <i>p</i> < 0.05). The MR resection and LR recession dose was positively correlated with the horizontal deviation (<i>p</i> < 0.001), but showed no significant correlation with AL (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>Exotropia with high myopia had a greater surgical dose response than those without high myopia. No significant difference was found in LR recession dose, but the MR resection dose was significantly lower in the high myopia group.</p>","PeriodicalId":12488,"journal":{"name":"Frontiers in Medicine","volume":"12 ","pages":"1588698"},"PeriodicalIF":3.1000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12256437/pdf/","citationCount":"0","resultStr":"{\"title\":\"The influence of high myopia-related exotropia on surgical dose-response in unilateral recession and resection surgery: a retrospective study.\",\"authors\":\"Chao Li, ZhiYin Lou, Fan Yang\",\"doi\":\"10.3389/fmed.2025.1588698\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To investigate the impact of high myopia on the surgical dose-response in unilateral recession and resection (R&R) surgery for exotropia.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 101 Chinese patients who underwent unilateral R&R surgery for concomitant exotropia between June 2021 and June 2024. Patients were divided into two groups based on axial length: those with high myopia (<i>n</i> = 38) and those without high myopia (<i>n</i> = 63). Surgical doses for lateral rectus (LR) recession and medial rectus (MR) resection were compared between the groups. Preoperative and postoperative deviations were measured, and statistical analyses were performed to assess the relationship between surgical dose, axial length (AL), and other clinical variables.</p><p><strong>Results: </strong>Age, duration of exotropia, and AL differed significantly between the groups, but other baseline characteristics were comparable. The LR recession dose did not differ significantly between the high myopia group (6.40 ± 1.11 mm) and the non-high myopia group (6.74 ± 1.00 mm, <i>p</i> > 0.05). However, the MR resection dose was significantly lower in the high myopia group (5.77 ± 1.02 mm) compared to the non-high myopia group (6.32 ± 0.92 mm, <i>p</i> < 0.05). The MR resection and LR recession dose was positively correlated with the horizontal deviation (<i>p</i> < 0.001), but showed no significant correlation with AL (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>Exotropia with high myopia had a greater surgical dose response than those without high myopia. No significant difference was found in LR recession dose, but the MR resection dose was significantly lower in the high myopia group.</p>\",\"PeriodicalId\":12488,\"journal\":{\"name\":\"Frontiers in Medicine\",\"volume\":\"12 \",\"pages\":\"1588698\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12256437/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3389/fmed.2025.1588698\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fmed.2025.1588698","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
目的:探讨高度近视对单侧外斜视退切手术剂量反应的影响。方法:回顾性分析2021年6月至2024年6月期间101例中国单侧共同性外斜视R&R手术患者。根据视轴长度将患者分为高度近视组(n = 38)和非高度近视组(n = 63)。比较两组间切除外侧直肌(LR)和内侧直肌(MR)的手术剂量。测量术前和术后偏差,并进行统计分析,评估手术剂量、轴向长度(AL)和其他临床变量之间的关系。结果:年龄、外斜视持续时间和AL在两组之间有显著差异,但其他基线特征具有可比性。高度近视组(6.40 ± 1.11 mm)与非高度近视组(6.74 ± 1.00 mm, p > 0.05)之间LR消退剂量无显著差异。然而,切除先生剂量显著降低高度近视组(5.77 ±1.02 毫米)相比non-high近视组(6.32 ±0.92 mm, p p p > 0.05)。结论:高度近视眼外斜视的手术剂量反应高于非高度近视眼。高度近视组LR消退剂量差异无统计学意义,MR切除剂量明显低于高度近视组。
The influence of high myopia-related exotropia on surgical dose-response in unilateral recession and resection surgery: a retrospective study.
Objective: To investigate the impact of high myopia on the surgical dose-response in unilateral recession and resection (R&R) surgery for exotropia.
Methods: A retrospective analysis was conducted on 101 Chinese patients who underwent unilateral R&R surgery for concomitant exotropia between June 2021 and June 2024. Patients were divided into two groups based on axial length: those with high myopia (n = 38) and those without high myopia (n = 63). Surgical doses for lateral rectus (LR) recession and medial rectus (MR) resection were compared between the groups. Preoperative and postoperative deviations were measured, and statistical analyses were performed to assess the relationship between surgical dose, axial length (AL), and other clinical variables.
Results: Age, duration of exotropia, and AL differed significantly between the groups, but other baseline characteristics were comparable. The LR recession dose did not differ significantly between the high myopia group (6.40 ± 1.11 mm) and the non-high myopia group (6.74 ± 1.00 mm, p > 0.05). However, the MR resection dose was significantly lower in the high myopia group (5.77 ± 1.02 mm) compared to the non-high myopia group (6.32 ± 0.92 mm, p < 0.05). The MR resection and LR recession dose was positively correlated with the horizontal deviation (p < 0.001), but showed no significant correlation with AL (p > 0.05).
Conclusion: Exotropia with high myopia had a greater surgical dose response than those without high myopia. No significant difference was found in LR recession dose, but the MR resection dose was significantly lower in the high myopia group.
期刊介绍:
Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
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