Frontiers in Physiology最新文献

{"title":"Chronic alcohol-related myopathy: a closer look at the role of lipids.","authors":"Muni Swamy Ganjayi, Thomas A Krauss, Craig R G Willis, Cory W Baumann","doi":"10.3389/fphys.2024.1492405","DOIUrl":"https://doi.org/10.3389/fphys.2024.1492405","url":null,"abstract":"<p><p>Chronic alcohol-related myopathy (CAM), characterized by muscle atrophy and weakness, arises from prolonged excessive ethanol (EtOH) intake. The precise mechanisms by which EtOH induces skeletal muscle atrophy are not fully understood. This article posits that the pathophysiology of CAM may be significantly influenced by how EtOH modifies lipid profiles and alters lipid composition and content in skeletal muscle. We review existing literature on lipid alterations in CAM-afflicted individuals and analogous animal models, discuss EtOH's direct and indirect effects on skeletal muscle lipids, and present specific instances where lipids contribute to muscle atrophy. This article advocates for a novel viewpoint, suggesting that lipid dysregulation may be the principal factor in EtOH-induced muscle wasting, offering a different angle to approach CAM research and treatment strategies.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"15 ","pages":"1492405"},"PeriodicalIF":3.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential impact of GLP-1 receptor agonists on male fertility: a fable of caution.","authors":"Stefan S Du Plessis, Temidayo S Omolaoye, Walter D Cardona Maya","doi":"10.3389/fphys.2024.1496416","DOIUrl":"https://doi.org/10.3389/fphys.2024.1496416","url":null,"abstract":"","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"15 ","pages":"1496416"},"PeriodicalIF":3.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of school-based high-intensity interval training on health-related fitness in adolescents.","authors":"Rade Jovanović, Mladen Živković, Mima Stanković, Dajana Zoretić, Nebojša Trajković","doi":"10.3389/fphys.2024.1487572","DOIUrl":"https://doi.org/10.3389/fphys.2024.1487572","url":null,"abstract":"<p><strong>Background: </strong>High-intensity interval training (HIIT) in school settings has been much less studied in adolescents. The aim of this study was to examine the impact of HIIT on health-related fitness in adolescents.</p><p><strong>Methods: </strong>The total sample consisted of 60 adolescents (age 16.33 ± 0.62 years) from secondary Grammar school, randomly divided into two groups: the experimental (EG) (30) and the control group (CG) (30). The experimental program (12-weeks; 2 times per week) involved two Tabata sessions during one physical education class lasting 4 min each. Participants were tested for health-related fitness components-cardiorespiratory fitness (The Shuttle Run Test (SRT) and strength, hand grip test, standing long jump (SLJ) and counter movement jump (CMJ).</p><p><strong>Results: </strong>Both the EG and the CG experienced significant positive changes in SRT (meters) and VO_2max values compared to baseline value (<i>p</i> < 0.05), however, the increase in the EG was significantly higher than that in the CG (SRT - η_p ² = 0.111; VO_2max - η_p ² = 0.111, <i>p</i> < 0.01). The EG showed significant improvement in SRT (meters) and VO_2max values compared to the CG (<i>p</i> < 0.01). Regarding the hand grip test results, a significant time × group interaction was found only for right hand (<i>p</i> < 0.01). Moreover, the improvements in SLJ and CMJ values was greater in EG than that in the CG group (SLJ- η_p ² = 0.182; CMJ- η_p ² = 0.112, <i>p</i> < 0.01).</p><p><strong>Conclusion: </strong>Findings indicate that HIIT implemented into physical education classes can result in significant improvements in selected health related fitness components in adolescents.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"15 ","pages":"1487572"},"PeriodicalIF":3.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11604620/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Broiler breeder putative lipid biomarkers associated with sperm mobility.","authors":"A Bond, K M Mills, C R Ferreira, I Harford, B Flack, J A Long, K Diehl","doi":"10.3389/fphys.2024.1504557","DOIUrl":"https://doi.org/10.3389/fphys.2024.1504557","url":null,"abstract":"<p><strong>Introduction: </strong>Biomarkers indicative of sperm mobility in broiler breeders would provide the ability to screen for fertility potential, with a positive correlation established between sperm mobility and fertilization potential. This study characterized the lipidome of seminal plasma (SP), sperm cell (SC), and whole semen (WS) isolated from broiler breeder roosters with different sperm mobility phenotypes across key timepoints of the semen production cycle.</p><p><strong>Methods: </strong>WS samples were collected from five high mobility roosters and five low mobility roosters during early, mid, and late semen production, with SP separated from SC by centrifugation. Using multiple reaction monitoring (MRM) profiling, a total of 3241 lipid species were identified in rooster semen across ten lipid classes. Metaboanalyst 6.0 was used to analyze the relative ion intensity for each lipid species due to sperm mobility phenotype through a t-test and due to timepoint through a one-way ANOVA, with lipid ontology enrichment analysis performed using LION. Metaboanalyst 6.0 was also used to perform biomarker analysis for the sperm mobility phenotype in WS samples.</p><p><strong>Results: </strong>Lipid class total abundance differed with sample type, sperm mobility phenotype, and timepoint. A total of 31, 99, and 112 lipid species were found to be different between low and high mobility males across timepoints in the SP, SC, and WS samples, respectively. Lipid ontology enrichment analysis revealed stark contrasts in lipid-based functions key to sperm survival, storage, and productivity between low and high sperm mobility phenotypes. Through biomarker analysis, 8 lipid species were identified as excellent sperm mobility biomarkers that could be detected in early and mid-semen production.</p><p><strong>Discussion: </strong>Timepoint based changes in lipid species were unique to each sperm mobility phenotype, with low sperm mobility roosters exhibiting a larger number of lipid species changes over the semen production cycle in the SP and SC when compared to high sperm mobility roosters. This is the first study to characterize poultry semen lipidome using MRM profiling. The lipid species identified between low and high sperm mobility roosters could be utilized in the poultry industry as potential biomarkers of fertility potential, with the ability to screen for the economical trait of fertility potential early in semen production.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"15 ","pages":"1504557"},"PeriodicalIF":3.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11604622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Graft-derived cell free DNA: used for assessment of early graft status and its implications for long-term kidney function.","authors":"Liang Wei, Yongheng Zhao, Shaoping Deng, Shaoping Wu, Hailian Wang, Xiangwei Luo, Hongji Yang","doi":"10.3389/fphys.2024.1440799","DOIUrl":"https://doi.org/10.3389/fphys.2024.1440799","url":null,"abstract":"<p><strong>Background: </strong>The long-term graft survival is closely related to its early status, yet the indices for assessing the early graft status are complex and lack quantitative values. The aim of this study is to investigate the potential of GcfDNA as a comprehensive, non-invasive, convenient, and quantifiable indicator for evaluating early graft status.</p><p><strong>Methods: </strong>In this study, 138 recipients who underwent primary kidney transplantation were enrolled. Peripheral blood samples, each 10 mL, were collected on days 1 and 7 post-transplantation. The quantification of both the graft cell-free DNA (GcfDNA) fraction (%) and GcfDNA concentration (copies per milliliter, cp/mL) was performed using droplet digital PCR (ddPCR).</p><p><strong>Results: </strong>For most recipients, both the GcfDNA fraction and concentration had a rapid decline at 7 days post-transplantation, reaching median values of approximately 0.7% and 53.5 cp/mL, respectively. No significant associations were found between GcfDNA values and other clinical parameters. On the seventh postoperative day, we observed a significant elevation in GcfDNA concentration among recipients with eGFR values < 60 mL/min/1.73 m². Additionally, notable increases were identified in both GcfDNA fraction and concentration variations within this specific subgroup. The findings of our study indicate a negative correlation between the concentration and fractional changes of GcfDNA on postoperative days 1 and 7, as well as the GcfDNA concentration on postoperative day 7, with eGFR within the 1-2 years post-transplantation period. The ROC curve of GcfDNA_Copies_Variation. day1-day 7 showed the highest AUC value AUC = 0.8006, with high sensitivity (90.14%) and specificity (77.61%), and PPV and NPV were 81.01% and 88.14%, respectively. Using four classical algorithm models, we found that the xgboost regression model achieved the best predictive performance (area under the curve (AUC) values = 0.862) for eGFR within 1-2 years post-transplantation, with high sensitivity (85.7%) and specificity (85%).</p><p><strong>Conclusion: </strong>The changes of GcfDNA levels in the early stage are closely related to kidney function within 1-2 years post-transplantation. As a comprehensive indicator of graft function, GcfDNA has great potential for clinical application.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"15 ","pages":"1440799"},"PeriodicalIF":3.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11604621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Six weeks of polarized functional interval training with large training load reductions does not affect performance gains compared to traditional workouts.","authors":"Steffen Held, Eduard Isenmann, Ludwig Rappelt, Tim Wiedenmann, Dominic Kutschki, Jannik Harbrecht, Katrin Kirchner, Stephan Geisler, Lars Donath","doi":"10.3389/fphys.2024.1446837","DOIUrl":"https://doi.org/10.3389/fphys.2024.1446837","url":null,"abstract":"<p><strong>Purpose: </strong>High-intensity functional interval training (HIFT) is predominantly composed of high exercise training intensities (HiT) and loads. Both have been linked to a higher risk of overtraining and injuries in inexperienced populations. A polarized training approach is characterized by high amounts of low-intensity training (LiT) and only approximately 5%-20% HiT. Compared to HIT-based training, this approach can result in temporary training load and intensity reductions without diminishing training gains. Thus, we aimed to examine the effects of traditional (TRAD) HIFT vs. polarized (POL) HIFT on relevant performance parameters.</p><p><strong>Methods: </strong>Thirty athletes (15 females, age: 26.6 ± 5.0 years, height: 1.76 ± 0.13 m, body mass: 79.6 ± 12.4 kg, prior experience: 2.3 ± 2.0 years, training volume: 6.1 ± 2.4 h/wk) were randomly assigned to 6 weeks of either POL (78% LiT, 22% threshold intensity training (ThT) to HiT) or TRAD (26% LiT, 74% ThT to HiT). HIFT performance testing focused on maximal strength (squat: SQ1RM, deadlift: DL1RM, overhead press: OHP1RM, high pull: HP1RM), endurance (peak oxygen uptake: V̇O₂peak, lactate threshold: LT, peak power output (PPO), and benchmark HIFT workout (Jackie: 1000 m rowing, 50 thrusters, and 30 pull-ups for time).</p><p><strong>Results: </strong>POL (785 ± 71 au) completed significantly (<i>p</i> ≤ 0.001; SMD = 4.55) lower training load (eTRIMP) than TRAD (1,273 ± 126 au). rANCOVA revealed no statistical relevant group×time interaction effects (0.094 ≤ <i>p</i> ≤ 0.986; 0.00 ≤ η_p ² ≤ 0.09) for SQ1RM, DL1RM, OHP1RM, high pull, V̇O2peak, LT, PPO, and Jackie performance. Both groups revealed trivial to moderate but significant (rANCOVA time effects: <i>p</i> ≤ 0.02; 0.01 ≤ η_p ² ≤ 0.11; 0.00 ≤ SMD ≤ 0.65) performance gains regarding DL1RM, OHP1RM, HP1RM, and Jackie.</p><p><strong>Conclusion: </strong>Despite a notably lower total training load, conditioning gains were not affected by a polarized functional interval training regimen.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"15 ","pages":"1446837"},"PeriodicalIF":3.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11604715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of co-administration of apricot kernels and caffeine on adult male diabetic albino rats.","authors":"Ahmed El Sayed Nour El-Deen, Ahmad Mohamad Taha, Almoatazbellah Elsayed, Ahmed Noaman Ali, Reda Samir Taha","doi":"10.3389/fphys.2024.1358177","DOIUrl":"10.3389/fphys.2024.1358177","url":null,"abstract":"<p><p>The purpose of this study is to evaluate the impacts of apricot kernels and caffeine on blood glucose, lipid profile, insulin secretion, and antioxidant effect in diabetic rats. Forty adult male albino rats were divided into five groups: normal control, diabetic control, diabetic rats treated with apricot kernels, diabetic rats treated with caffeine, and diabetic rats treated with apricot kernels plus caffeine. Fasting samples were collected at the end of the study for analysis, and pieces of liver and pancreatic tissues were removed for histological analysis. There was a significant decrease in blood glucose, glycated hemoglobin, body weight, total cholesterol, triglyceride, and low-density lipoprotein cholesterol (LDL-C) levels and a significant increase in insulin and high-density lipoprotein cholesterol (HDL-C) levels in the kernel and caffeine-treated groups. However, there was little histological alteration in the liver or pancreas, and no significant differences were observed in the histological findings between groups. Overall, it can be concluded that apricot kernel and caffeine had a positive effect in decreasing blood glucose and harmful lipid profile and that caffeine had a synergistic effect on the apricot kernel.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"15 ","pages":"1358177"},"PeriodicalIF":3.2,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11602279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Animal study on factors influencing anterograde renal pelvis perfusion manometry.","authors":"Xin Liu, Xing Li, Limin Liao","doi":"10.3389/fphys.2024.1258175","DOIUrl":"10.3389/fphys.2024.1258175","url":null,"abstract":"<p><strong>Objects: </strong>Anterograde renal pelvis perfusion manometry is an effective method to assist in the diagnosis of upper urinary tract obstruction.</p><p><strong>Methods: </strong>To established a rat model of partial ureteral obstruction to explore the perfusion rate, renal pelvis volume, obstruction sites, contralateral upper urinary tract, and lower urinary tract functions, which may affect anterograde renal pelvis perfusion manometry. To measure the renal pelvis volume using ultrasound. Depending on whether clamped the contralateral ureter and it continuously emptied the bladder, perfused the renal pelvis at rate of 15, 30, 60, 90, or 120 mL/h to measure the pressure synchronously.</p><p><strong>Results: </strong>The research showed the renal pelvis volume of UPJ and UVJ at 1, 2, 3, and 4 weeks respectively, significantly increased compared with the control group. Comparison of the renal pelvis volume between the UPJ and UVJ groups was not statistically significant. The renal pelvis pressure of UPJ and UVJ was significantly increased compared with the control group, and the UVJ group was greater than the UPJ group. The renal pelvic pressure increased as the perfusion rate increased. Comparing the renal pelvis pressure measured using synchronous bladder emptying with the renal pelvis pressure measured singly, the difference was statistically significant. Comparing the renal pelvis pressure measured using synchronous bladder emptying with measured with a clamped contralateral ureter, the difference was not statistically significant; however, in some groups, the difference was statistically significant. Measuring the renal pelvis pressure singly and clamping the contralateral ureter, the difference was not statistically significant, except in some groups, the difference was significant.</p><p><strong>Conclusion: </strong>The study suggested that ureter obstruction sites, perfusion rates, renal pelvis volumes, and synchronous bladder emptying affects the renal pelvis pressure. The function of the contralateral upper urinary tract did not affect renal pelvis pressure in the short term.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"15 ","pages":"1258175"},"PeriodicalIF":3.2,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11602502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual roles of methoprene-tolerant gene <i>TaMet</i> in male molting and female reproduction of the tomato leafminer, <i>Tuta absoluta</i> (meyrick).","authors":"Tingwei Zhang, Kai Xu, Deqian Liu, Hang Ma, Wenbiao Liu, Wenjia Yang","doi":"10.3389/fphys.2024.1500391","DOIUrl":"10.3389/fphys.2024.1500391","url":null,"abstract":"<p><p>The tomato leafminer (<i>Tuta absoluta</i>) is a highly destructive global quarantine pest. The methoprene-tolerant (Met) protein, a member of the bHLH/PAS family of transcription factors, forms complexes with other family members to transduce the juvenile hormone signal, which regulates insect growth and development. However, the functions of the <i>TaMet</i> gene have rarely been studied in <i>T. absoluta</i>. Herein, we investigated the significance of <i>TaMet</i> in <i>T. absoluta</i>. Spatiotemporal expression analysis revealed that <i>TaMet</i> exhibited comparable expression patterns in males and females, with high expression levels during the early pupal and early adult stages. <i>TaMet</i> was predominantly expressed in the female ovary and male wing. <i>TaMet</i> knockdown impaired ovarian development in female adults, causing irregular arrangement and increased spacing of the egg epithelial cells in the ovary. Silencing <i>TaMet</i> also led to a 67.25% reduction in female spawning and a 67.21% decrease in the offspring hatching rate. Furthermore, the vitellogenin content was significantly diminished, and the expression levels of vitellogenin (<i>Vg</i>) and vitellogenin receptor (<i>VgR</i>) genes were significantly downregulated. In contrast, silencing <i>TaMet</i> in 3-day-old male pupae resulted in an 80% mortality rate and various phenotypic abnormalities, including body melanism, molting defects, and wing deformities. Moreover, the expression levels of wing development and chitin metabolism genes decreased significantly after knocking down <i>TaMet.</i> Our results indicate that <i>TaMet</i> plays a significant dual role in male molting and female reproduction of <i>T. absoluta</i>.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"15 ","pages":"1500391"},"PeriodicalIF":3.2,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11603827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clockwork precision: egg-laying-induced rise of body temperature is seasonally programmed in a wild bird.","authors":"Magella Guillemette, Yannick Seyer, Anouck Viain","doi":"10.3389/fphys.2024.1490877","DOIUrl":"10.3389/fphys.2024.1490877","url":null,"abstract":"<p><p>There is long time interest about the phenology of plants and animals living in seasonal environments as research in that field would help to understand the coping mechanisms leading to a higher fitness. For instance, it has been shown several decades ago that birds prepare themselves 2-4 months before the actual start of the breeding season by slowly growing reproductive organs. In parallel, the resting metabolic rate increase during reproduction in various vertebrates including mammals, reptiles, and birds. Recently, it has been reported that body temperature of a marine bird species was reaching an annual peak during egg-laying, raising the question about the seasonal dynamic of this important physiological feature. Using data loggers implanted in the abdominal cavity of female Common Eiders (<i>Somateria mollissima mollissima</i>) for a full year, we show here that daily body temperature (<i>T</i> _b.daily) is slowly increasing first and then accelerating at the approach of the laying period. Because the rise of <i>T</i> _b.daily is tightly associated with egg-laying in this species, we also analysed the influence of ambient temperature (water and air) and photoperiod on this seasonal dynamic. Based on the various mechanisms at work and a parsimonious interpretation of the data, we conclude that photoperiod is the main cue driving the seasonal breeding program of eiders. Although the laying dates of the instrumented females were highly clustered over a period of 4 years, we speculated that the remaining variation observed was the result of eco-physiological challenges occurring over the years.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"15 ","pages":"1490877"},"PeriodicalIF":3.2,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}