Frontiers in Nutrition最新文献

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Six months of different exercise type in sedentary primary schoolchildren: impact on physical fitness and saliva microbiota composition. 久坐不动的小学生六个月不同类型的运动:对体能和唾液微生物群组成的影响。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1465707
Annamaria Mancini, Daniela Vitucci, Vito Alessandro Lasorsa, Corrado Lupo, Paolo Riccardo Brustio, Mario Capasso, Stefania Orrù, Alberto Rainoldi, Federico Schena, Pasqualina Buono
{"title":"Six months of different exercise type in sedentary primary schoolchildren: impact on physical fitness and saliva microbiota composition.","authors":"Annamaria Mancini, Daniela Vitucci, Vito Alessandro Lasorsa, Corrado Lupo, Paolo Riccardo Brustio, Mario Capasso, Stefania Orrù, Alberto Rainoldi, Federico Schena, Pasqualina Buono","doi":"10.3389/fnut.2024.1465707","DOIUrl":"https://doi.org/10.3389/fnut.2024.1465707","url":null,"abstract":"<p><strong>Introduction: </strong>Lifestyle influences microbiota composition. We previously reported a healthier microbiota composition in saliva from active schoolchildren compared to sedentary. In the present study, we evaluated the effects of 6 months of different exercise types on physical fitness and saliva microbiota composition in 8-11-years-old sedentary schoolchildren.</p><p><strong>Methods: </strong>Sixty-four sedentary children from five primary schools in Turin, Italy, were divided into three groups: one continued normal curricular activity while two underwent different exercise protocols for 6 months. The Structured Exercise (Sa) group did 2 h per week of muscle activation, strength and coordination exercises supervised by a kinesiologist. The Daily Mile (Dm) group did 1 h per week of Sa plus 15 min of walking/running outdoors four times a week, supervised by a class teacher; control group (Ct) did 2 h a week of curricular exercise supervised by a class teacher. Physical fitness was evaluated before and after the intervention. Saliva samples were collected post-intervention in all participants and analyzed using PCR amplification of 16S rRNA bacterial genes. The Amplicon Sequence Variants were filtered, decontaminated, and phylogenetically classified using DADA2 software. Differential abundance analysis of microbiome taxa and pathway data was conducted using the LEfSe algorithm and PICRUSt.</p><p><strong>Results: </strong>The Sa group showed better performances in lower limb power and sprint performance while both the Sa and Dm groups improved in endurance and balance at the end of the intervention; only balance resulted slightly improved in the Ct group. Among the genera differently enriched in saliva after the training intervention, we found that the <i>Prevotella</i>, the <i>Dubosiella</i> and the <i>Family XIII AD3011 group</i> were the most abundant in the Sa group; differently, the <i>Neisseria</i> and the <i>Abiotrophia</i> in Ct group. Four species showed significant the <i>Prevotella melaninogenica</i> and the <i>Prevotella nanceiensis</i> were more abundant in the Sa, conversely, <i>Gemella sanguinis</i> was enriched in Dm and <i>Abiotrophia defectiva</i> in Ct saliva group.</p><p><strong>Conclusion: </strong>We demonstrated that Sa and Dm, not curricular exercise, improve the physical fitness components in sedentary schoolchildren correlated to health and promote an enrichment in saliva microbiota species associated to a healthier profile.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1465707"},"PeriodicalIF":4.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11542257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of non-high-density lipoprotein cholesterol-to-high-density lipoprotein cholesterol ratio (NHHR) with gout prevalence: a cross-sectional study. 非高密度脂蛋白胆固醇与高密度脂蛋白胆固醇比率(NHHR)与痛风患病率的关系:一项横断面研究。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1480689
Xia Guo, Haoxuan Chu, Hanchi Xu, Shipeng Wang, Jiahuan He, Yushi Wang
{"title":"Association of non-high-density lipoprotein cholesterol-to-high-density lipoprotein cholesterol ratio (NHHR) with gout prevalence: a cross-sectional study.","authors":"Xia Guo, Haoxuan Chu, Hanchi Xu, Shipeng Wang, Jiahuan He, Yushi Wang","doi":"10.3389/fnut.2024.1480689","DOIUrl":"https://doi.org/10.3389/fnut.2024.1480689","url":null,"abstract":"<p><strong>Background: </strong>The non-high-density lipoprotein cholesterol (non-HDL-C)-to-high-density lipoprotein cholesterol (HDL-C) ratio (NHHR) is a strong lipid marker that has been associated with atherogenic features. This study aimed to investigate the potential association between the NHHR and gout prevalence.</p><p><strong>Methods: </strong>This study investigated the relationship between the NHHR and gout by analyzing data gathered from the National Health and Nutrition Examination Survey (NHANES), a research study conducted in the United States from 2007 to 2018. All participants in NHANES provided written informed consent prior to participation. The NHHR was calculated as the ratio of non-HDL-C to HDL-C. Total cholesterol (TC) and HDL-C levels were sourced from NHANES laboratory data. Gout was assessed using a questionnaire. Weighted logistic regression analysis, subgroup analysis, and smoothed curve fitting were performed.</p><p><strong>Results: </strong>This study included 30,482 participants. The fully adjusted models showed that for each unit increase in NHHR in continuous variables, there was a 10% higher likelihood of gout prevalence (OR: 1.10, 95% CI: 1.05, 1.16). Analysis of the NHHR quartiles revealed that patients in the highest quartile had a notably greater probability of developing gout than those in the lowest quartile. (Q4 vs. Q1, OR: 1.34, 95% CI: 1.05, 1.71). Subgroup analyses yielded consistent results across categories, indicating a significant positive association between the NHHR and gout. E-value analysis suggested robustness to unmeasured confounding. Interaction tests showed that the race, education level, marital relationship, poverty-income ratio (PIR), hypertension, smoking habits, estimated glomerular filtration rate (eGFR), lipid-lowering therapy, and diabetes had no discernible effects on this association. The <i>p</i>-values for all the interactions were > 0.05. Nevertheless, the relationship between the NHHR and gout was significantly affected by the age and sex of the participants (interaction <i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>Among adults in the United States, elevated NHHR levels are correlated with increased odds of gout prevalence.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1480689"},"PeriodicalIF":4.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glaucoma and dietary links: insights from high-salt intake, the Mediterranean diet, and specific nutrients. 青光眼与饮食的关系:从高盐摄入量、地中海饮食和特定营养素中获得的启示。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1461748
Yuqi Yang, Hongyan Zhou, Zhang Hong
{"title":"Glaucoma and dietary links: insights from high-salt intake, the Mediterranean diet, and specific nutrients.","authors":"Yuqi Yang, Hongyan Zhou, Zhang Hong","doi":"10.3389/fnut.2024.1461748","DOIUrl":"https://doi.org/10.3389/fnut.2024.1461748","url":null,"abstract":"<p><p>Glaucoma, a prevalent and potentially blinding eye disease, is linked to a variety of factors, including elevated intraocular pressure, optic nerve damage, and oxidative stress. In recent years, dietary habits, as a controllable lifestyle factor, have received increasing attention in the prevention and treatment of glaucoma. The purpose of this review was to investigate the effects of dietary factors on glaucoma, with a particular emphasis on two common dietary patterns: the high-salt diet and the Mediterranean diet. In addition, we investigated the association between many particular nutrients (including omega-3 fatty acids, vitamins, caffeine, and minerals) and glaucoma to fully assess the potential involvement of dietary variables in glaucoma pathogenesis, prevention, and treatment. This article reveals the importance of dietary components in glaucoma prevention and explores prospective possibilities for future research by conducting a comprehensive review of previous scientific studies.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1461748"},"PeriodicalIF":4.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional intervention in end-stage renal disease: a clinical trial study. 终末期肾病的营养干预:临床试验研究。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1322229
Xueting Tao, Jiaolin Qian, Yongwei Hu
{"title":"Nutritional intervention in end-stage renal disease: a clinical trial study.","authors":"Xueting Tao, Jiaolin Qian, Yongwei Hu","doi":"10.3389/fnut.2024.1322229","DOIUrl":"https://doi.org/10.3389/fnut.2024.1322229","url":null,"abstract":"<p><strong>Objective: </strong>Chronic kidney disease is a global health problem, and end-stage renal disease (ESRD) has a major impact on patients' quality of life and prognoses. However, studies on individualized nutritional therapy for patients with ESRD need more complementary evidence.</p><p><strong>Methods: </strong>A clinical study was conducted based on a small population. It included patients with ESRD who underwent dialysis treatment in the Taicang Hospital Department of Nephrology, Soochow University, China, between January 2019 and December 2021. According to the randomized number table method, patients were divided into the nutritional treatment group (NIG) and the non-nutritional intervention control group (NNIG). There were 84 patients in the NIG and 92 patients in the NNIG. This study analyzed the changes in residual renal function (RRF) and indicators of blood and kidney function in ESRD with personalized nutritional therapy.</p><p><strong>Results: </strong>The results show that nutritional interventions for ESRD are effective in reducing the rate of decline in RRF and improving indicators of blood and kidney function in patients with ESRD. It was also found that patients with diabetes mellitus gained fewer health benefits per unit of RRF improvement with individualized nutritional therapy.</p><p><strong>Conclusion: </strong>This study provides important information about the treatment effects and factors associated with individual nutritional interventions in a population with ESRD. These results contribute to a better understanding of the effects of nutritional therapy in ESRD and provide a basis for managing it. Further studies should focus on specific populations and potential interventions to improve patient prognosis.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1322229"},"PeriodicalIF":4.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between relative fat mass and low-carbohydrate diet scores and sleep disorders in United States: a real-world cross-sectional study. 美国相对脂肪量和低碳水化合物饮食评分与睡眠障碍之间的关系:一项真实世界横断面研究。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-24 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1500934
Cheng Cao, Keyi Yu, Fuquan Lin, Aie Xu, Miaoni Zhou
{"title":"Relationship between relative fat mass and low-carbohydrate diet scores and sleep disorders in United States: a real-world cross-sectional study.","authors":"Cheng Cao, Keyi Yu, Fuquan Lin, Aie Xu, Miaoni Zhou","doi":"10.3389/fnut.2024.1500934","DOIUrl":"https://doi.org/10.3389/fnut.2024.1500934","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the relationship between relative fat mass (RFM) and low-carbohydrate diet (LCD) scores and sleep disorders in the U.S. population.</p><p><strong>Methods: </strong>Data were collected from the National Health and Nutrition Examination Survey (NHANES) conducted between 2005 and 2014. A total of 5,394 respondents participated in the study. Univariate and multivariate linear regression analyses were used to investigate the relationship between RFM and LCD scores, and univariate and multivariate logistic regression analyses were used to investigate the relationship between RFM and LCD scores and sleep disorders. Restricted cubic spline (RCS) analyses were conducted to test for nonlinear associations between RFM and LCD scores and sleep disorders.</p><p><strong>Results: </strong>A total of 5,394 participants were included in the statistical analysis, including 5,080 healthy participants and 314 with sleep disorders. Univariate and multivariate linear regression showed a bivariate positive correlation between RFM and LCD scores (<i>p</i> < 0.05), and logistic regression analysis showed a significant positive correlation between RFM (95% CI: 1.02-1.07, <i>p</i> = 0.005) LCD scores (95% CI: 1.00-1.03, <i>p</i> = 0.044) and sleep disturbances. Subgroup analyses showed robust effects of RFM and LCD score on sleep disorders.</p><p><strong>Conclusion: </strong>RFM was positively and bi-directionally associated with LCD scores, both of which resulted as risk factors for sleep disorders. This study emphasizes that an LCD and lowering RFM can prevent and ameliorate the risk of sleep disorders.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1500934"},"PeriodicalIF":4.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Independent and joint influence of depression and advanced lung cancer inflammation index on mortality among individuals with chronic kidney disease. 抑郁症和晚期肺癌炎症指数对慢性肾病患者死亡率的独立和共同影响。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1453062
Jie Zhou, Wenjun Liu, Xiaoxin Liu, Jijun Wu, Ying Chen
{"title":"Independent and joint influence of depression and advanced lung cancer inflammation index on mortality among individuals with chronic kidney disease.","authors":"Jie Zhou, Wenjun Liu, Xiaoxin Liu, Jijun Wu, Ying Chen","doi":"10.3389/fnut.2024.1453062","DOIUrl":"10.3389/fnut.2024.1453062","url":null,"abstract":"<p><strong>Background: </strong>The combined effect of depression and nutritional-inflammatory status on mortality in the chronic kidney disease (CKD) population is unclear.</p><p><strong>Methods: </strong>We prospectively analyzed 3,934 (weighted population: 22,611,423) CKD participants from the National Health and Nutrition Examination Survey (2007-2018). Depression and nutritional-inflammatory status were assessed with Patient Health Questionnaire 9 (PHQ-9) and Advanced Lung Cancer Inflammation Index (ALI), respectively. Weighted multivariate COX regression models, restricted cubic splines (RCS) models, and stratified analyses were used to investigate the association of PHQ-9 scores and ALI with all-cause mortality.</p><p><strong>Results: </strong>During a median follow-up of 5.8 years (interquartile range 3.4-8.6 years), a total of 985 patients died (25.0%). Each point increase in a patient's PHQ-9 score increased the risk of all-cause mortality by 4% (HR, 1.04; 95% CI, 1.02-1.06; <i>p</i> < 0.001), in the full adjusted model. However, an increase in ALI levels was associated with a decreased risk. HRs (95% CI) of 0.76 (0.65-0.90), 0.70 (0.57-0.86), and 0.51 (0.41-0.64) in the Q2, Q3, and Q4 of ALI compared with the Q1 of ALI, respectively. In addition, the joint analysis showed that CKD patients without depression and with higher ALI were associated with a reduced risk of all-cause mortality. Namely, patients in the highest ALI group (Q4) without depression had the lowest risk (HR, 0.32; 95% CI, 0.21-0.48). Furthermore, this combined effect was consistent across all subgroups, and no significant interaction was found (<i>p</i> > 0.05 for interaction).</p><p><strong>Conclusion: </strong>In a nationally representative sample of US patients with CKD, coexisting depression and poorer nutrition-inflammation were associated with a significantly increased risk of all-cause mortality.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1453062"},"PeriodicalIF":4.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Nutritional status assessment and its links with chronic disease prognosis and surgical outcomes. 社论:营养状况评估及其与慢性病预后和手术效果的关系。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1481810
Gabriela Villaça Chaves, Barbara Perez Vogt, Geórgia das Graças Pena, Rodolfo Espinoza
{"title":"Editorial: Nutritional status assessment and its links with chronic disease prognosis and surgical outcomes.","authors":"Gabriela Villaça Chaves, Barbara Perez Vogt, Geórgia das Graças Pena, Rodolfo Espinoza","doi":"10.3389/fnut.2024.1481810","DOIUrl":"10.3389/fnut.2024.1481810","url":null,"abstract":"","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1481810"},"PeriodicalIF":4.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitamin C intake and osteoarthritis: findings of NHANES 2003-2018 and Mendelian randomization study. 维生素 C 摄入量与骨关节炎:NHANES 2003-2018 和孟德尔随机研究的结果。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1409578
Hongjie Zhang, Xuan Jiang, Lei Bai, Jiahui Chen, Wei Luo, Jianxiong Ma, Xinlong Ma
{"title":"Vitamin C intake and osteoarthritis: findings of NHANES 2003-2018 and Mendelian randomization study.","authors":"Hongjie Zhang, Xuan Jiang, Lei Bai, Jiahui Chen, Wei Luo, Jianxiong Ma, Xinlong Ma","doi":"10.3389/fnut.2024.1409578","DOIUrl":"10.3389/fnut.2024.1409578","url":null,"abstract":"<p><strong>Background: </strong>The role of vitamin C in osteoarthritis (OA) is still a subject of debate. Our aim was to combine the National Health and Nutrition Examination Survey (NHANES) and MR studies to explore the relationship between vitamin C intake and OA.</p><p><strong>Methods: </strong>Clinical information on participants during NHANES 2003-2018 was collected and the relationship between vitamin C intake and OA risk was assessed using logistic regression modelling. In MR analyses, three methods were used to explore the causality of vitamin C intake with OA. Sensitivity analysis to verify the stability of the MR study.</p><p><strong>Results: </strong>The cross-sectional study included a total of 31,527 participants, categorizing them into low (<30.2 mg), medium (30.2-93.0 mg) and high (>93.0 mg) level groups based on their vitamin C intake levels. Logistic regression models showed that vitamin C intake was not associated with OA risk (<i>p</i> > 0.05). Inverse-variance weighted (IVW) method of MR study showed no causality between vitamin C intake and OA (OR = 0.993, 95% CI: 0.901 ~ 1.095, <i>p</i> = 0.882). Sensitivity analysis indicated that the MR study was reliable.</p><p><strong>Conclusion: </strong>Our cross-sectional and MR studies showed that vitamin C intake was not associated with OA risk. More researches are needed in the future to investigate the link between vitamin C and OA.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1409578"},"PeriodicalIF":4.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the synergy of enzymes, nutrients, and gene networks in rice starch granule biogenesis. 探索水稻淀粉粒生物发生过程中酶、营养物质和基因网络的协同作用。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1448450
Sunil Indrajit Warwate, Monika Awana, Swapnil S Thakare, Veda Krishnan, Suresh Kumar, Haritha Bollinedi, Ajay Arora, Amitha Mithra Sevanthi, Mrinmoy Ray, Shelly Praveen, Archana Singh
{"title":"Exploring the synergy of enzymes, nutrients, and gene networks in rice starch granule biogenesis.","authors":"Sunil Indrajit Warwate, Monika Awana, Swapnil S Thakare, Veda Krishnan, Suresh Kumar, Haritha Bollinedi, Ajay Arora, Amitha Mithra Sevanthi, Mrinmoy Ray, Shelly Praveen, Archana Singh","doi":"10.3389/fnut.2024.1448450","DOIUrl":"10.3389/fnut.2024.1448450","url":null,"abstract":"<p><strong>Introduction: </strong>Rice is a primary food source almost for more than 50% of the total world's population. Glycemic index (GI) is high in most of the rice varieties, limiting their consumption by diabetic and obese people. As a result, developing new rice varieties with low GI necessitates a thorough understanding of starch biogenesis gene expression and its interrelationship.</p><p><strong>Methods: </strong>A total 200 rice genotypes were analyzed for total starch content (TSC), amylopectin content (APC), and amylose content (AC). The clustering of these rice genotypes was done based on their AC. Further, these genotypes were categorized into three groups up to 10% amylose-low, 10-26% amylose-medium, and more than 26% amylose-high. Among them, six genotypes 1 from low AC (NJ-72), 2 from medium AC (UPRI-2003-18, PRR-126), and 3 from high AC (RNRM-7, Urvashi and Ananga) were selected. The genotypes selected from the medium and high AC groups were having 2% amylose variation among themselves respectively and they were further used to study the level of RS, protein content (PC), fatty acid (FA) profiles, and granule morphology along with low group sample.</p><p><strong>Results: </strong>Resistant starch (RS) content ranged from 0.33-2.75%, and fatty acid profiling revealed high levels of palmitic, linoleic, and oleic acids. The degree of crystallinity and APC% were found to be positively correlated. Ananga, the genotype with the highest RS, displayed compact starch granules. Further, NJ-72 showing low RS and Ananga with high RS were selected for investigation of enzymatic activities of starch biosynthesis, metabolites accumulation, and expressions of 20 starch biogenesis genes in developing endosperm. Starch branching enzymes (SBE) and starch synthase (SS) activities peaked at 13 days after anthesis (DAA), while starch debranching enzymes (DBE) were most active at 18 DAA. In Ananga, TSC, AC, APC, and RS levels progressively increased from 3 to 23 DAA. Ananga showed 1.25-fold upregulation of <i>granule-bound starch synthase I (GBSSI)</i> at 18DAA. Higher expressions of <i>SSI</i> and <i>SBEIIb</i> were observed in NJ-72 at 13DAA. <i>PUL2</i> was predominantly expressed followed by <i>ISA1</i>. GBSSI was positively correlated with both AC and RS while <i>SS, SBE</i>, and <i>DBE</i> were positively related to APC.</p><p><strong>Conclusion: </strong>This research could lead to the development of rice varieties with improved nutritional qualities, such as higher RS content, which is beneficial for human health due to its role in lowering glycemic response and promoting gut health. Additionally, the study provides insights into how the modulation of key genes and enzymes can affect starch composition, offering strategies to breed rice varieties tailored for specific dietary needs or industrial applications.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1448450"},"PeriodicalIF":4.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Balancing opportunity and exploitation: unpaid internships in sports nutrition. 平衡机会与剥削:运动营养学中的无薪实习。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1462046
Nicola Brown
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