Frontiers in Nutrition最新文献

{"title":"The relationships of serum vitamin D concentration with linear speed and change of direction performance in soccer players.","authors":"M M Michalczyk, M Kałuża, G Zydek, R Roczniok, A Golas","doi":"10.3389/fnut.2024.1501643","DOIUrl":"10.3389/fnut.2024.1501643","url":null,"abstract":"<p><p>The aim of the study was to establish whether the level of 25 hydroxyvitamin D (25(OH)D) in serum has an influence on speed (m/s) and change of direction (COD, s) performance. Twenty male soccer players from the top league participated in the study. All subjects were evaluated for the serum concentration of 25(OH)D at the beginning of the preseason. The linear sprint test was performed at 5 m and 30 m, and COD (time and deficit) at the beginning (BPP) and after (APP) 6 weeks of the preparatory period. The results revealed that 20% of soccer players had a significant deficiency of 25(OH)D (<20 ng/mL) and 30% had insufficient 25(OH)D levels (between 20 and 30 ng/mL). Positive correlations were found between the training effect for the ∆COD (BPP-APP) (<i>p</i> = 0.003) and ∆deficit (BPP-APP) (<i>p</i> = 0.039). Significant differences were noticed for the ∆COD (m = 0.60 [s]) and ∆deficit (m = 0.56[s]) in the soccer players whose 25(OH)D concentration was <=30 ng/mL, and for the ∆COD (<i>p</i> = 0.002) and ∆deficit (<i>p</i> = 0.017) in the soccer players whose 25(OH)D concentration was >30 ng/mL. The training effect was significantly higher for the soccer players whose 25(OH)D concentration was above 30 ng/mL. Soccer players with higher 25(OH)D levels achieved superior results in the COD test and demonstrated better deficit outcomes, affirming the positive influence of 25(OH)D on muscle metabolism.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1501643"},"PeriodicalIF":4.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic potential of flavonoids from traditional Chinese medicine in pancreatic cancer treatment.","authors":"Qi Wan, Qing Ren, Shuangying Qiao, Aiping Lyu, Xingwei He, Fangfei Li","doi":"10.3389/fnut.2024.1477140","DOIUrl":"10.3389/fnut.2024.1477140","url":null,"abstract":"<p><p>Pancreatic cancer (PC) is a highly aggressive malignancy with rising mortality rates globally. Its diagnosis is often challenging due to its asymptomatic nature in the early stages. Consequently, most patients receive a poor prognosis, with low survival rates within 5 years, as the disease is typically detected at an advanced stage, complicating effective treatment. Flavonoids, especially those derived from traditional Chinese herbal medicines, have attracted considerable attention for their potent anti-PC properties. This review highlights the therapeutic potential of these bioactive compounds, which modulate key biological pathways, making them promising candidates for PC intervention. Their mechanisms of action include the regulation of autophagy, apoptosis, cell growth, epithelial-mesenchymal transition, and oxidative stress, as well as enhancing chemotherapeutic sensitivity, exerting antiangiogenic effects, and potentially boosting immunomodulatory responses. The demonstrated benefits of these natural compounds in cancer management have spurred extensive academic interest. Beyond their role as anti-cancer agents, flavonoids may provide both preventive and therapeutic advantages for PC, resonating with the core principles of traditional Chinese medicine for disease prevention and holistic treatment.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1477140"},"PeriodicalIF":4.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11620852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What specific exercise training is most effective exercise training method for patients on maintenance hemodialysis with sarcopenia: a network meta-analysis.","authors":"Ying Li, Jingjing Li, Xiaoan Chen, Yuegong Shi, Jie Shen, Ting Huang","doi":"10.3389/fnut.2024.1484662","DOIUrl":"10.3389/fnut.2024.1484662","url":null,"abstract":"<p><strong>Objective: </strong>The present study aimed to investigate the influence of different exercise methods on sarcopenia patients receiving maintenance hemodialysis (MHD) by conducting a network meta-analysis.</p><p><strong>Methods: </strong>The PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), and Wanfang databases were searched online for relevant articles published until May 2024. Based on the inclusion and exclusion criteria, we selected 10 articles that compared the effects of 7 exercise interventions on sarcopenia patients receiving MHD.</p><p><strong>Results: </strong>The results of network meta-analysis showed that resistance training (RT) [standardized mean difference (SMD) = 4.54; 95% confidence interval (CI): 3.27-5.80] significantly improved the handgrip strength (HGS) of sarcopenia patients receiving MHD as compared to Baduanjin exercise (BAE) (SMD = 4.19; 95% CI: 2.31-6.07), bicycle exercise (BIE) (SMD = 4.06; 95% CI: 0.02-8.10), and combined movement (CE) (SMD = 3.50; 95% CI: 3.13-3.87). Compared to normal care (NC), BAE (SMD = 0.15; 95% CI: 0.07-0.23), RT (SMD = 0.34; 95% CI: 0.06-0.62), and CE (SMD = 0.37; 95% CI: 0.16-0.58) significantly improved skeletal muscle mass index (SMI) in sarcopenia patients receiving MHD.</p><p><strong>Conclusion: </strong>This study showed that RT has a positive effect on improving HGS in sarcopenia patients receiving MHD. CE also showed good results in enhancing SMI in MHD patients with sarcopenia. More randomized controlled trials are required to better understand the effectiveness of these exercise interventions and the potential underlying mechanisms.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1484662"},"PeriodicalIF":4.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The dietary inflammatory index and asthma prevalence: a cross-sectional analysis from NHANES.","authors":"Chuansen Lu, Yike Zhu","doi":"10.3389/fnut.2024.1485399","DOIUrl":"10.3389/fnut.2024.1485399","url":null,"abstract":"<p><strong>Background: </strong>Inflammation is a key factor in the development of asthma, and diet significantly influences inflammatory responses. This study examines the relationship between the Dietary Inflammatory Index (DII) and asthma prevalence.</p><p><strong>Methods: </strong>We conducted a cross-sectional analysis using data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018. Demographic details, anthropometric measurements, dietary habits, lifestyle factors, and asthma status were recorded for all participants. Multivariable logistic regression was utilized to assess the relationship between DII and asthma prevalence. Additionally, restricted cubic spline (RCS) analysis was employed to explore the nonlinearity and dose-response relationship between DII and asthma risk. Subgroup analyses were stratified by gender, age, race, body mass index (BMI), poverty income ratio (PIR), education, smoking status, alcohol use, and family medical history to dissect the association between DII and asthma across diverse populations.</p><p><strong>Results: </strong>The analysis included 37,283 adults from NHANES. After adjusting for potential confounders in the multivariable logistic regression model, a significant positive association was identified between DII and asthma (OR, 95% CI: 1.05, 1.02-1.09, per 1 SD increase). The RCS analysis revealed a nonlinear association (<i>p</i> for nonlinearity = 0.0026), with an inflection point at 1.366, beyond which an increase in DII was significantly associated with asthma risk. Furthermore, the stratified analyses indicated a positive association between DII and asthma in the majority of subgroups.</p><p><strong>Conclusion: </strong>The findings underscore a significant and nonlinear association between DII and asthma. To enhance asthma prevention and management, greater emphasis should be placed on modulating dietary-induced inflammation.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1485399"},"PeriodicalIF":4.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of Composite Dietary Antioxidant Index on the relationship between eczema and depression symptoms in US adults.","authors":"Tian Zhang, Ruohua Zhang, Ting Song, Fang Chen, Yuegang Wei","doi":"10.3389/fnut.2024.1470833","DOIUrl":"10.3389/fnut.2024.1470833","url":null,"abstract":"<p><strong>Aims: </strong>The study aims to explore the associations of eczema, Composite Dietary Antioxidant Index (CDAI), with depression symptoms in adults based on the National Health and Nutrition Examination Surveys (NHANES) database.</p><p><strong>Methods: </strong>In total, 3,402 participant data were extracted from the NHANES 2005-2006. The relationship between eczema, CDAI, and depression symptoms was explored by utilizing weighted univariate and multivariate logistic regression models, presenting as odds ratios (ORs) and 95% confidence intervals (CIs). The additive interaction between eczema, CDAI, and depression symptoms was measured by relative excess risk due to interaction (RERI) and the attributable proportion of interaction (AP). Subsequently, the associations of eczema, CDAI, with depression were also explored in different gender, body mass index (BMI), and smoking subgroups.</p><p><strong>Results: </strong>Of the 3,402 participants included, the mean age was 46.76 (0.83) years old, and 174 (5.11%) participants had depression symptoms. In the adjusted model, both eczema (OR = 3.60, 95%CI: 2.39-5.40) and CDAI (OR = 1.97, 95%CI: 1.19-3.27) were associated with a higher prevalence of depression symptoms. Compared to the participants with high CDAI and no eczema, those participants with low CDAI (eczema: OR = 7.30, 95%CI: 4.73-11.26; non-eczema: OR = 1.84, 95%CI: 1.06-3.19) have higher odds of depression symptoms, no matter have eczema or not. When under low CDAI levels, eczema was associated with increased odds of depression symptoms (OR = 3.76, 95%CI: 2.34-6.03). When under low CDAI level, eczema was also related to elevated odds of depression symptoms in those males, females, BMI <25, BMI ≥25, non-smoking, and smoking.</p><p><strong>Conclusion: </strong>CDAI could modulate the association of eczema with depression symptoms in adults.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1470833"},"PeriodicalIF":4.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11620884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the association between non-alcoholic fatty liver disease and mortality in United States adults.","authors":"Fen Rong, Yiyi Mai, Lujia Shou, Xinya Zhu, Meiyue Li, Liuchen Zhu, Xiuli Sun, Xinhua Zhao","doi":"10.3389/fnut.2024.1502671","DOIUrl":"10.3389/fnut.2024.1502671","url":null,"abstract":"<p><strong>Background: </strong>Non-alcoholic Fatty Liver Disease (NAFLD) is a prevalent condition characterized by the accumulation of fat in the liver, often linked with increased risk for multi-systemic diseases. This study aims to investigate the relationship between NAFLD and mortality, particularly all-cause and cardiovascular mortality, among United States adults.</p><p><strong>Methods: </strong>Data from the National Health and Nutrition Examination Survey (NHANES) were utilized, encompassing 80,312 participants from 2003-2004 to 2017-2018. After exclusions for incomplete data, potential other liver diseases, and significant alcohol consumption, the final analytical cohort included 32,698 participants. The Fatty Liver Index (FLI), a non-invasive diagnostic tool, was used to identify NAFLD. Covariates included demographic characteristics, lifestyle factors, and biochemical parameters. Survival analysis was conducted using a weighted Cox proportional hazards regression model to quantify the impact of NAFLD on mortality.</p><p><strong>Results: </strong>The study revealed that NAFLD was significantly associated with increased risks of all-cause and cardiovascular disease (CVD) mortality. The hazard ratios (HRs) from the survival analysis consistently indicated a higher risk among participants with NAFLD compared to those without. Subgroup analyses further confirmed the association, with notable exceptions in certain subgroups such as those with high school education and diabetes. Additionally, a nonlinear relationship between serum uric acid (SUA) levels and mortality risk was identified among NAFLD participants.</p><p><strong>Conclusion: </strong>Non-alcoholic Fatty Liver Disease is a significant risk factor for all-cause and CVD mortality in US adults. The findings underscore the importance of early detection and intervention for NAFLD to mitigate its impact on public health. Further research is needed to explore the complex interactions between NAFLD, SUA levels, and mortality, particularly in high-risk subgroups.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1502671"},"PeriodicalIF":4.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11620881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between composite dietary antioxidant index and cognitive function impairment among the US older adults: a cross-sectional study based on the NHANES 2011-2014.","authors":"Cong Zhao, Meng Pu, Chengji Wu, Jiaqi Ding, Jun Guo, Guangyun Zhang","doi":"10.3389/fnut.2024.1471981","DOIUrl":"10.3389/fnut.2024.1471981","url":null,"abstract":"<p><strong>Background: </strong>Cognitive function impairment (CFI) and the Composite Dietary Antioxidant Index (CDAI) were investigated in this study.</p><p><strong>Methods: </strong>Participants from the 2011-2014 cycles of the National Health and Nutrition Examination Survey were chosen to assess cognitive function using the Consortium to Establish a Registry for Alzheimer's Disease Word Learning Test, the Animal Fluency Test, and the Digit Symbol Substitution Test. Participants scored below the 25% percentile of any of the three tests were defined as having cognitive function impairment. 24-h recalls of diet were collected to calculate CDAI.</p><p><strong>Results: </strong>2,424 participants were included. The fully adjusted multivariate logistic regression model showed an increase of one CDAI unit reduced CFI risk by 5% (95% CI: 0.92 ~ 0.98, <i>p</i> = 0.004). When comparing individuals with the lowest CDAI in the first quartile (<-2.42), the adjusted odds ratio for CDAI and CFI were 0.81 (95% CI: 0.61 ~ 1.06, <i>p</i> = 0.125) in the second quartile, 0.69 (95% CI: 0.51 ~ 0.92, <i>p</i> = 0.012) in the third quartile, and 0.59 (95% CI: 0.43 ~ 0.82, <i>p</i> = 0.002) in the fourth quartile, respectively. Restricted cubic spline analysis revealed a steady negative linear correlation between CDAI and CFI, with a <i>p</i>-value for non-linearity of 0.122. Subgroup analysis did not reveal any significant interactions based on age, education level, family income, history of diabetes, hypertension, stroke, and depression.</p><p><strong>Conclusion: </strong>CDAI was inversely associated with CFI in a large representative American population. Further longitudinal studies are needed for causal inference.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1471981"},"PeriodicalIF":4.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive global review and methodological framework for developing food atlases.","authors":"Ghadir Fallata, Rasil Alhadi, Luluh Alnashmi, Shahad Aljohani, Fatimah Alsaeed","doi":"10.3389/fnut.2024.1505606","DOIUrl":"10.3389/fnut.2024.1505606","url":null,"abstract":"<p><strong>Introduction: </strong>An atlas is a trustworthy resource created from precise data collection that serves as a guide for communities. A food atlas is a useful tool for analyzing dietary data. There is a growing need for a food atlas that is part of the nation's strategy to help the health sector with specific nutritional or dietary assessments of individual consumption and overall wellbeing. Although researchers previously attempted to create a food atlas on a national level, the process of data collection was not well defined.</p><p><strong>Methods: </strong>This study provides an overview of global food atlases that can be used to develop a procedure manual to guide experts in creating a dependable food atlas.</p><p><strong>Results: </strong>To date, 27 countries have developed food atlases for various reasons. After examining these countries' experiences, six important steps in the procedure manual that should be considered when developing a food atlas were identified: choosing the most consumed food, using traditional cooking utensils, determining portion sizes, capturing photographs of the food, validating the food atlas, and publishing the food atlas.</p><p><strong>Discussion: </strong>This procedure manual can be used as a guide until a validation study is conducted.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1505606"},"PeriodicalIF":4.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11620897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnesium depletion score and gout: insights from NHANES data.","authors":"Xu Cao, Haixia Feng, Huijie Wang","doi":"10.3389/fnut.2024.1485578","DOIUrl":"10.3389/fnut.2024.1485578","url":null,"abstract":"<p><strong>Objectives: </strong>Gout is associated with hyperuricemia, and serum magnesium levels are negatively correlated with uric acid levels. Magnesium intake is also associated with a reduced risk of hyperuricemia. However, the relationship between the magnesium depletion score (MDS), which represents the systemic magnesium status, and gout is unclear. This study was conducted to investigate the association between MDS and gout as well as explore the impact of dietary magnesium intake on this relationship.</p><p><strong>Methods: </strong>We analyzed 18,039 adults with gout data who participated in the National Health and Nutrition Examination Survey between 2007 and 2016. Magnesium deficiency status was assessed using the MDS, a comprehensive scoring tool. Considering the possible effects of dietary magnesium intake, weighted multivariable logistic regression and subgroup analyses were used to assess the correlation between MDS and gout.</p><p><strong>Results: </strong>The overall prevalence of gout among adults in the United States between 2007 and 2016 was 4.7%. After adjusting for confounders, MDS and gout risk showed a significant positive correlation. Individuals with an MDS of 2 and ≥ 3 had higher odds of gout than those with an MDS of 0 (MDS = 2, odds ratio: 1.86 [1.18-2.93], <i>p</i> = 0.008; MDS = 3, odds ratio: 2.17 [1.37-3.43], <i>p</i> = 0.001; <i>p</i> for trend <0.001). Dietary magnesium intake did not moderate the correlation between MDS and gout risk.</p><p><strong>Conclusion: </strong>A positive correlation exists between magnesium deficiency, as quantified using the MDS, and gout risk among adults in the United States. Additionally, dietary magnesium intake did not alter this association.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1485578"},"PeriodicalIF":4.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11617175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary niacin intake and mortality among chronic kidney disease patients.","authors":"Zhengxi Zhou, Xiaotian Yao","doi":"10.3389/fnut.2024.1435297","DOIUrl":"10.3389/fnut.2024.1435297","url":null,"abstract":"<p><strong>Background: </strong>The relationship between niacin and the risk of mortality in chronic kidney disease (CKD) patients remains unclear. This study aims to investigate the potential correlation.</p><p><strong>Methods: </strong>This cohort study utilized data from the 2003-2018 National Health and Nutrition Examination Survey (NHANES). The study included 6,110 patients with CKD aged 18 years or older. Weighted Cox proportional hazards models and restricted cubic splines (RCS) were employed to estimate hazard ratios for all-cause mortality and cardiovascular disease (CVD) mortality. Niacin intake was estimated using the 24 h dietary recall method, based on the type and amount of food consumed. All-cause mortality and cardiac mortality rates were determined using National Death Index (NDI) mortality data (as of 31 December 2018).</p><p><strong>Results: </strong>The median niacin intake was 20.89 mg/day, with an interquartile range of 15.67-27.99 mg/day. During the follow-up period (median of 87 months), there were 1,984 all-cause deaths, including 714 CVD deaths. Compared with low niacin intake, the multivariate-adjusted hazard ratio for dietary intake of 22 mg or higher was 0.71 (95% CI, 0.57-0.88) for all-cause mortality and 0.75 (95% CI, 0.57, 0.98) for CVD mortality.</p><p><strong>Conclusion: </strong>Dietary niacin intake is associated with a reduction in all-cause and cardiac mortality among CKD patients.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1435297"},"PeriodicalIF":4.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11617148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}