Kadriye Can, Gonul Filoglu, Gokhan Ersoy, Deniz Ozmen, A Emre Eskazan, M Cem Ar, Ozlem Bulbul
{"title":"Evaluation of DNA methylation-based age prediction accuracy in leukemia patients using a six-CpG model trained on healthy blood.","authors":"Kadriye Can, Gonul Filoglu, Gokhan Ersoy, Deniz Ozmen, A Emre Eskazan, M Cem Ar, Ozlem Bulbul","doi":"10.1007/s12024-026-01238-1","DOIUrl":"10.1007/s12024-026-01238-1","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"910-920"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147767076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Thali, Alexander Braun, Ralph P Braun, Mia Hannah Thali, Dominic Gascho
{"title":"Forensic 3D avatars - AI-assisted injury detection and interactive digital-twin visualization.","authors":"Michael Thali, Alexander Braun, Ralph P Braun, Mia Hannah Thali, Dominic Gascho","doi":"10.1007/s12024-026-01200-1","DOIUrl":"10.1007/s12024-026-01200-1","url":null,"abstract":"<p><p>This feasibility study explores the application of a dermatology-based 3D full-body scanning system (VECTRA WB360) combined with artificial intelligence (AI) software for forensic documentation. The system generates high-resolution, color-accurate 3D avatars within minutes, enabling automated detection, localization, and measurement of simulated injuries. AI-assisted analysis reliably identified cutaneous findings, including in anatomically challenging regions, and displayed them in an interactive forensic dashboard. Advantages include speed, standardization, and anatomically precise localization. Limitations concern dermatology-focused training data, motion artifacts, and costs. With forensic-specific AI modules and validation, this approach may significantly improve efficiency, objectivity, and admissibility in forensic medicine.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"921-928"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147325226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fatal giant cell myocarditis associated with shingles of the left upper chest.","authors":"Theodore Estrin-Serlui, Thomas Prickett","doi":"10.1007/s12024-026-01182-0","DOIUrl":"10.1007/s12024-026-01182-0","url":null,"abstract":"<p><p>Varicella Zoster Virus (VZV), following an initial chicken pox infection earlier in life, can occasionally reactivate in dorsal nerve root ganglia to cause shingles, classically diagnosed by a vesicular skin eruption/rash in a single dermatome. We report a sudden death of an elderly woman with shingles of the left upper chest and axilla. A post mortem examination identified the cause of death as giant cell myocarditis, and VZV was identified in myocardial tissue. This is the first example in the literature of shingles associated with histologically-proven giant cell myocarditis and fatality in an otherwise immunocompetent patient. This case highlights an unexpected finding only identified using post mortem histology. It also adds to the body of evidence suggesting that VZV could potentially reactivate in both autonomic and sensory ganglia at the same time during episodes of shingles.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1012-1015"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146200741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fatal intracerebral hemorrhage in a pregnant woman following varicella zoster virus infection: a rare neurological complication.","authors":"Kirthika Ravi, Rahul Panwar, Raghvendra Singh Shekhawat, Sudeep Khera","doi":"10.1007/s12024-026-01216-7","DOIUrl":"10.1007/s12024-026-01216-7","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1070-1075"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147491074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julian Wirtz, Yu-Cheng Guo, Maximilian Timme, Sven Schmidt, Andreas Schmeling
{"title":"The time frame of third molar mineralization in a northern chinese population.","authors":"Julian Wirtz, Yu-Cheng Guo, Maximilian Timme, Sven Schmidt, Andreas Schmeling","doi":"10.1007/s12024-025-01131-3","DOIUrl":"10.1007/s12024-025-01131-3","url":null,"abstract":"<p><p>A key criterion in dental age determination is the assessment of third molar mineralization. The objective of this study was to provide reference data for Demirjian stages D-H of teeth 38 and 48 in a northern Chinese population. To this end, 988 digital orthopantomograms (OPGs) of northern Chinese individuals aged 12-26 years were examined. Of the total sample, 822 OPGs showed at least one evaluable lower third molar. The mean ages for both teeth in males are above 18 years from stage G onwards. In females, the mean ages for both teeth are above 18 years from stage F onwards. The youngest individuals with mineralization stage H were older than 18.0 years in both sexes. Since studies with larger case numbers have also reported minimum ages for this stage below the age of 18, the minimum ages for stage H presented in this study cannot be recommended for age assessment practice. In order to avoid stage misclassifications, which are particularly problematic when applying the minimum age principle, stage classifications in future studies should be made consensually by experienced examiners.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"977-983"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145488377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Federica Amirante, Roberto Catanesi, Biagio Solarino, Felice Carabellese, Anna Margari
{"title":"A fatal case of Munchausen syndrome by proxy in the father-daughter dyad.","authors":"Federica Amirante, Roberto Catanesi, Biagio Solarino, Felice Carabellese, Anna Margari","doi":"10.1007/s12024-026-01231-8","DOIUrl":"10.1007/s12024-026-01231-8","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1091-1098"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147510620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characteristics of infant deaths with positive hair toxicology.","authors":"N Thomson, J Fronczek, M Lynch, J L Schumann","doi":"10.1007/s12024-026-01174-0","DOIUrl":"10.1007/s12024-026-01174-0","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1029-1036"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luiz Alberto Marques, Annie Seabra Medeiros Antunes, Thaiza Gonçalves Rocha, Carla Barros de Oliveira, Márcia Barcelos Gomes Silvares, José Vicente-Gomila, Mariana Leonel Martins, Lucianne Cople Maia, Andréa Fonseca-Gonçalves, Andreia Cristina Breda de Souza, Maria Augusta Visconti
{"title":"Evolution of facial identification techniques: A bibliometric analysis (1970 - 2022).","authors":"Luiz Alberto Marques, Annie Seabra Medeiros Antunes, Thaiza Gonçalves Rocha, Carla Barros de Oliveira, Márcia Barcelos Gomes Silvares, José Vicente-Gomila, Mariana Leonel Martins, Lucianne Cople Maia, Andréa Fonseca-Gonçalves, Andreia Cristina Breda de Souza, Maria Augusta Visconti","doi":"10.1007/s12024-026-01307-5","DOIUrl":"10.1007/s12024-026-01307-5","url":null,"abstract":"<p><strong>Purpose: </strong>This study performed a bibliometric analysis of global research on human facial recognition for forensic purposes, identifying trends in techniques, anatomical regions, and methodological evolution over five decades.</p><p><strong>Methods: </strong>Six databases (PubMed, Scopus, Web of Science, Embase, BVS, and Lilacs) were searched without language or year restrictions. We included studies focusing on human identification through clinical or imaging facial examinations. Data regarding year, journal, authors, keywords, age group, examination type, and methods (metric, morphological, or volumetric) were extracted. Two independent investigators used Rayyan™ for selection, and descriptive analysis was performed using VantagePoint™ and Excel™.</p><p><strong>Results: </strong>From 5016 identified articles, 424 studies published between 1970 and 2022 were included (four systematic reviews, three clinical, 377 observational, and 40 laboratory studies). Forensic Science International was the leading journal (n = 113), and Stephan CN was the most prolific author. Photography was the most used examination (n = 125). Metric analysis prevailed as the primary method (n = 221). While the total face was the most frequent focus (n = 239), the nose emerged as the most studied isolated region (n = 20). Most studies (n = 415) reported identification results.</p><p><strong>Conclusion: </strong>Facial identification research has grown significantly, with photography and metric methods remaining the current standards. However, bibliometric trends point toward a paradigm shift: the integration of Artificial Intelligence and 3D volumetric analysis is emerging as a critical frontier to overcome the limitations of conventional 2D techniques, offering superior precision and optimized forensic workflows.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1151-1166"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148583942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reconsidering whole organ retention in forensic autopsies: toward global harmonization of brain and heart sampling protocols.","authors":"M Vijayasimha","doi":"10.1007/s12024-025-01104-6","DOIUrl":"10.1007/s12024-025-01104-6","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"986"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145279500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Dhanya Dedeepya, Vaishali Goel, Nivedita Nikhil Desai
{"title":"Comment on \"Sudden cardiac death in young adults and the role of antipsychotic drugs: a multicenter autopsy study\".","authors":"S Dhanya Dedeepya, Vaishali Goel, Nivedita Nikhil Desai","doi":"10.1007/s12024-025-01136-y","DOIUrl":"10.1007/s12024-025-01136-y","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1189-1190"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145556521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}