Davide Ferorelli, Gianmarco Sirago, Francesco Calò, Annachiara Vinci, Paolo Visci, Biagio Solarino, Alessandro Dell'Erba
{"title":"An overview of Metaverse in healthcare. Potential application in forensic and legal medicine.","authors":"Davide Ferorelli, Gianmarco Sirago, Francesco Calò, Annachiara Vinci, Paolo Visci, Biagio Solarino, Alessandro Dell'Erba","doi":"10.1007/s12024-025-00938-4","DOIUrl":"10.1007/s12024-025-00938-4","url":null,"abstract":"<p><p>In this review, we holistically consider healthcare as an ecosystem that includes forensic pathology and legal medicine and probe why these areas have largely ignored the use of Metaverse. This effort is directed at understanding the potential impact of virtual worlds on these areas and ultimately asks if forensic sciences are missing an opportunity or multiple opportunities. We reviewed the scientific literature to identify clinical trials and observational or other study types using PubMed Central, Web of Science, Scopus, and Cochrane, including terms related to the Metaverse and healthcare, with a screen of 1,200 relevant articles. Applications were from future clinical applications, training, treatment, prediction/prevention, and diagnosis, focusing on finding blanks in forensic and legal medicine. The study carried out in-depth research with the Metaverse regarding all areas of medicine. Despite this, significant forensic pathology or legal medicine research has yet to be identified. The gap may implicate a critical oversight in forensic areas, specifically autopsies, crime scene investigation, and field reconstruction of legal cases that could benefit from implementing virtual simulations. In this regard, incorporating virtual environments in these areas can provide new training tools, case scenarios, and even a revision mechanism for cold cases, leading to an essential trend in the evolution of legal medicine.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1386-1395"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark Nielsen, Julie Munkholm, Jytte Banner, Carl Johan Wingren
{"title":"Injury rates following conducted electrical weapons and other less-lethal force modalities in real-life police settings: a comparative literature review.","authors":"Mark Nielsen, Julie Munkholm, Jytte Banner, Carl Johan Wingren","doi":"10.1007/s12024-025-01020-9","DOIUrl":"10.1007/s12024-025-01020-9","url":null,"abstract":"<p><p>The aim of this study was to rank the rate and risk ratio of subject injury following exposure to less-lethal force modalities in real-life police interventions. The purpose was to observe whether the use of conductive electrical weapons (CEW) qualifies as a low-risk modality of force, with a similar risk of adverse health outcomes as exposure to other less-lethal modalities, such as physical force, baton, oleoresin capsicum (OC) spray, and canine. A literature search was conducted using the scientific databases PubMed, Embase, and Web of Science. We rated the included articles based on quality and calculated the weighted means of injury rates. We found 19 articles reporting the rate or risk ratio of injury following exposure to common less-lethal force modalities in real-life settings. OC spray appeared to have the lowest rate of subject injury. The outcome for subject injury following CEW was ambiguous but seemed to be lower in comparison to baton and canine. However, the findings should be interpreted with caution due to methodological limitations. The identified studies were heterogeneous in design, which limits the conclusions drawn. In general, there was an indication that the risk of injury is lowest when OC spray is used. The rate of subject injury following the use of CEW is lower compared to baton and canine. Further research using a systematic approach to the registration of injuries is warranted.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1396-1406"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harry Perkins, Adam B Rohrlach, Toby Hughes, Alex Forrest, Denice Higgins
{"title":"3D imaging for dental identification: a pilot investigation of a novel segmentation method using an intra oral scanning device.","authors":"Harry Perkins, Adam B Rohrlach, Toby Hughes, Alex Forrest, Denice Higgins","doi":"10.1007/s12024-025-00992-y","DOIUrl":"10.1007/s12024-025-00992-y","url":null,"abstract":"<p><strong>Introduction: </strong>Forensic dental identification relies on the comparison of antemortem and postmortem dental records. 3D dental imaging presents the potential for detailed anatomical features of teeth to be quantified between individuals in automated identification tools. This study introduces a novel segmentation method to simultaneously remove extraneous data from two images reducing processes and time required during 3D dental image comparisons, and tests this against existing approaches to better understand segmentation techniques for forensic purposes.</p><p><strong>Methods: </strong>Six volunteers had both digital and stone cast full arch dental models created. The casts were scanned and digitized with an intra oral laser scanner, and five different segmentation methods were then applied to all images. Segmented images were compared via a method for aligning 3D images for possible matching (same person) and non-matching (different person) pairings.</p><p><strong>Results: </strong>All segmentation methods removed adequate excess materials to provide consistent repeated outcomes in the comparison process, with the novel segmentation method showing equivalent outcomes with existing methodologies. The findings highlight the importance of understanding the process of segmentation in distinguishing between 3D dental imaging and underscore the potential of 3D imaging technologies in forensic odontology.</p><p><strong>Conclusion: </strong>The study demonstrates the efficacy of a new segmentation method in forensic dental identification, offering a faster approach; calling for further validation of these methods within a legal framework.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1213-1221"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fatal stray dog attack in Russian Federation: a case report based on CCTV documentation.","authors":"Galina Zolotenkova, Rizky Merdietio Boedi, Oleg Viktorovich Lysenko, Nikolaos Angelakopoulos","doi":"10.1007/s12024-025-01015-6","DOIUrl":"10.1007/s12024-025-01015-6","url":null,"abstract":"<p><p>Fatal dog attacks, though relatively rare, remain a significant public safety concern, particularly in regions with large stray dog populations. This case report details a fatal stray dog attack on a 77-year-old man in the Greater Moscow region, as documented through forensic examination and CCTV footage. The autopsy revealed extensive bite-related injuries, including severe vascular damage that led to exsanguination. The footage provided a unique and detailed account of the attack's sequence, highlighting the prolonged aggression exhibited by the dog. This case underscores the importance of forensic investigations, surveillance footage, and effective stray dog management strategies to mitigate similar incidents. Further research is needed to better understand the risk factors associated with fatal dog attacks and develop targeted prevention measures.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1334-1343"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiovascular-related death in infancy and childhood: a clinicopathological study of two referral institutions in England.","authors":"Marta C Cohen","doi":"10.1007/s12024-024-00884-7","DOIUrl":"10.1007/s12024-024-00884-7","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1577-1578"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Forensic expertise in evaluation of malpractice or complications in cases of early postpartum hemorrhage.","authors":"Dubravko Habek","doi":"10.1007/s12024-024-00893-6","DOIUrl":"10.1007/s12024-024-00893-6","url":null,"abstract":"","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1498-1499"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nora Fawzy Fnon, Asmaa F Sharif, Zahraa Khalifa Sobh
{"title":"The lethal fifth cardiac chamber: a rare autopsy case report of left atrial appendage aneurysm and review of literature.","authors":"Nora Fawzy Fnon, Asmaa F Sharif, Zahraa Khalifa Sobh","doi":"10.1007/s12024-025-00963-3","DOIUrl":"10.1007/s12024-025-00963-3","url":null,"abstract":"<p><p>Congenital left atrial appendage (LAA) aneurysm is an extremely rare condition characterized by abnormal dilatation of the LAA. We report a fatal case of a left atrial appendage aneurysm (LAAA). The presented case was a 19-year-old male who died suddenly during vigorous exercise with no relevant medical or family history. On gross examination, we observed a semi-rounded bulge at the LAA with a diameter of approximately 5 cm. Sectioning the bulge revealed an aneurysmal dilatation encompassing recent and huge lamellated mural thrombi filling its cavity. Though coronaries showed no stenosis, the mid-ventricular section of the heart showed dark and whitish areas at the lateral and posterior wall of the left ventricle, which were suspicious of myocardial infarctions. Histopathological examination depicted a thinned fibrosed wall of LAA, and the mural thrombi exhibited different stages of healing, which was confirmed using Martius Scarlet Blue stain. We identified myocardial infarctions at the suspected areas in the left ventricle, confirmed by the Masson Trichrome stain. The chronic myocardial ischemia was precipitated by the LAA aneurysmal compression of the left circumflex coronary artery as it passed along the atrioventricular groove. Seven other cases who died from LAAA complications since 1922 were reviewed. Early diagnosis and adequate management of LAAA allow survival without residual complications. Yet, this article highlighted the importance of screening for cardiac diseases in those subjected to vigorous exercise.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1299-1306"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luca Tomassini, Massimo Lancia, Cristiana Gambelunghe, Giulia Ricchezze, Piergiorgio Fedeli, Mariano Cingolani, Francesco De Micco, Elena Fiorucci, Roberto Scendoni
{"title":"Immunohistochemical insights into hypothermia-related deaths: a systematic review.","authors":"Luca Tomassini, Massimo Lancia, Cristiana Gambelunghe, Giulia Ricchezze, Piergiorgio Fedeli, Mariano Cingolani, Francesco De Micco, Elena Fiorucci, Roberto Scendoni","doi":"10.1007/s12024-024-00934-0","DOIUrl":"10.1007/s12024-024-00934-0","url":null,"abstract":"<p><strong>Purpose: </strong>Hypothermia occurs when core body temperature drops below 35 °C. The purpose of this review was to identify and analyze studies on the topic of hypothermia from an immunohistochemical perspective to determine robust markers of fatal hypothermia.</p><p><strong>Methods: </strong>This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines. It has been registered with Prospero (registration number: CRD42024572782).</p><p><strong>Results: </strong>In total, 2618 publications met the search criteria. A total of 63 duplicate articles were excluded and a further 2489 publications were excluded for not meeting the inclusion criteria, leaving 29 full-text articles. Furthermore, from the bibliographies of the included articles, four more publications were selected, which also respected the established inclusion and exclusion criteria. Only six studies identified a statistically significant correlation between immunohistochemical patterns and hypothermia-related deaths.</p><p><strong>Conclusion: </strong>The existing literature examined appears fragmented and lacks robust statistical validation. Therefore, there is an evident need for more comprehensive and methodologically rigorous research to develop reliable diagnostic criteria.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1358-1369"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Domestic violence and chronic traumatic encephalopathy (CTE) - a forensic perspective.","authors":"Marianne Tiemensma, Roger W Byard","doi":"10.1007/s12024-024-00856-x","DOIUrl":"10.1007/s12024-024-00856-x","url":null,"abstract":"<p><p>Chronic Traumatic Encephalopathy, or CTE, is an entity characterized by neurological deficits that are thought to arise from repetitive episodes of blunt head trauma. It has gained considerable attention recently in those who have engaged in contact sports. However, given that it is caused by mechanical cerebral strain from nonspecific blunt impact, it seems reasonable to assume that it could arise from a multitude of causes, such as craniocentric domestic violence. While the literature is somewhat contradictory, the possibilities are that CTE may be caused by either the incremental additive effects of less severe trauma, or from more forceful impacts, or from a combination of both of these mechanisms. Another issue to consider is the degree of acceleration/rotation trauma associated with particular events. Careful study of the chronology, nature and dose-relationships of previous head impacts in victims of inflicted lethal head trauma will, therefore, be required. This will help to clarify its significance in cases of domestic violence and also specifically whether it can be additive from more minor impacts, or whether there is a threshold of force required before it occurs.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1495-1497"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141445990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of authors' self-citation in contemporary forensic odontology literature.","authors":"N Angelakopoulos, N Polukhin, S B Balla","doi":"10.1007/s12024-024-00928-y","DOIUrl":"10.1007/s12024-024-00928-y","url":null,"abstract":"<p><p>This bibliometric investigation aimed to analyze trends in author self-citation within prominent forensic odontology literature and explore potential correlations between self-citation rates and publication attributes. We reviewed seven leading forensic sciences journals from 2003 to 2023. For this analysis, we focused on two specific timeframes: 2003-2007 and 2018-2023. Our review encompassed original research articles, reviews, and case reports. Eligible articles underwent detailed examination for article and author attributes and citation metrics. Utilizing univariable and multivariable negative binomial regression analyses, we explored potential associations between the number of self-citations and various publication characteristics. This study analyzed 415 articles related to forensic odontology, of which 237 (57.1%) included at least one self-citation. Key findings highlight prevalent topics such as dental age estimation and human dental identification. A significant portion of the studies involved prospective, retrospective, and cross-sectional designs, and there has been a notable increase in the number of reviews and meta-analyses in recent years compared to an equivalent past period. Self-citation was observed in over half of the analyzed articles, with a median total citation count of 31 and a median self-citation rate of 7.5%. Further bibliometric investigation is required to establish definitive conclusions regarding author self-citation patterns in forensic odontology literature, particularly by exploring longer time spans.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1127-1137"},"PeriodicalIF":1.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}