Forensic Science, Medicine and Pathology最新文献_第9页

Demographic, co-intoxicants and other characteristics of citalopram-involved overdose deaths. 与西酞普兰有关的用药过量死亡病例的人口统计学特征、共毒物特征和其他特征。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-09-06 DOI: 10.1007/s12024-024-00885-6

José E Muñoz, Marie A Abate, Zheng Dai, Gordon S Smith, James C Kraner, Allen R Mock

{"title":"Demographic, co-intoxicants and other characteristics of citalopram-involved overdose deaths.","authors":"José E Muñoz, Marie A Abate, Zheng Dai, Gordon S Smith, James C Kraner, Allen R Mock","doi":"10.1007/s12024-024-00885-6","DOIUrl":"10.1007/s12024-024-00885-6","url":null,"abstract":"Selective serotonin reuptake inhibitors (SSRIs) including citalopram are commonly used antidepressants that can be involved in drug-related deaths along with opioids and other substances. This study characterized citalopram involvement in West Virginia (WV) drug-related deaths compared to other SSRI and non-SSRI-related deaths. All 2005-2021 WV drug-related deaths were analyzed in this retrospective study. Demographics, other substances involved, and comorbidities in cases in which citalopram was listed on the death certificate were compared to other SSRI-related and total non-SSRI deaths. Citalopram concentrations and the association between citalopram presence with predicted fentanyl concentrations were determined. Citalopram was the most common antidepressant present in the deaths (4.5% of 14,363 total), with most (81%) unintentional. Male: female ratios in citalopram cases (0.9:1) were significantly lower than in non-SSRI deaths (2.3:1). Almost two-thirds of citalopram deaths had ≥ 4 substances involved compared to 26% of non-SSRI deaths. Overall, oxycodone was most frequently identified in citalopram deaths (fentanyl more commonly in recent years), followed by alprazolam and diazepam. Cardiovascular comorbidity was significantly more common in citalopram than non-SSRI deaths. No association was found between citalopram presence and predicted fentanyl concentrations. Most citalopram-related deaths were unintentional and involved proportionately more females, with larger numbers of concurrent substances present and more cardiovascular comorbidity compared to non-SSRI deaths. Citalopram is widely used and less toxic than many antidepressants. The extent to which it contributed to overdose deaths can be difficult to ascertain given the multiple substances usually present.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"80-89"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New geographic location data on the occurrence and abundance of carrion insects of forensic interest. 关于具有法医意义的腐生昆虫的出现和数量的新地理位置数据。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-01-30 DOI: 10.1007/s12024-024-00780-0

Beryl Morris

{"title":"New geographic location data on the occurrence and abundance of carrion insects of forensic interest.","authors":"Beryl Morris","doi":"10.1007/s12024-024-00780-0","DOIUrl":"10.1007/s12024-024-00780-0","url":null,"abstract":"The world's forensic entomologists have much in common. They face similar research challenges, apply the same scientific methodology, study the same kinds of evidence, and access global research databases. Nevertheless, some regional heterogeneity inevitably exists. For most countries, and particularly those that have complex and diverse ecosystems, the current priority is to stimulate use of forensic entomology by establishing open access databases with time series data using standardised protocols for occurrence, abundance, distribution, niche preferences, life cycle, and identification characteristics for the key regional species that may be encountered in forensic entomology cases. Even in countries where forensic entomology is routinely used as a tool in reconstructing the history of corpses found on crime scenes in accordance with principles found in the rapidly developing body of literature, there is still much to learn about forensically useful insects. Examples of regional gaps include the taxonomy of lesser-known carrion insect species, seasonal occurrence of carrion species in the country's various geographical regions, and rates of development of the local species modeled in the many site situations of forensic interest. The first published study of carrion insects found in Athens, Greece published in this journal is an example of entomologists in a region taking the necessary first step towards establishing baseline data about native and introduced species and hence, physiological and behavioural responses to local environmental conditions, including life cycles and likelihood of occurrence or absence in the region.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"460-462"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The micro CT evaluation of crown and root pulp volume versus dentin thickness in teeth in postmortem interval (PMI). 对死后间隔期（PMI）牙冠和牙根牙髓体积与牙本质厚度的显微 CT 评估。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-03-21 DOI: 10.1007/s12024-024-00805-8

Selcuk Cetin, Nihat Akbulut, Kaan Orhan, Burak Bilecenoglu, Mert Ocak, Emre Bayram, Ahmet Altan, Bulent Eren, Serkan Silsupur, Bedirhan Sezer Oner

{"title":"The micro CT evaluation of crown and root pulp volume versus dentin thickness in teeth in postmortem interval (PMI).","authors":"Selcuk Cetin, Nihat Akbulut, Kaan Orhan, Burak Bilecenoglu, Mert Ocak, Emre Bayram, Ahmet Altan, Bulent Eren, Serkan Silsupur, Bedirhan Sezer Oner","doi":"10.1007/s12024-024-00805-8","DOIUrl":"10.1007/s12024-024-00805-8","url":null,"abstract":"Determining the postmortem interval (PMI) is one of the main study subjects of forensic sciences. The main purpose of this prospective in vitro study that was the Micro-CT evaluation of teeth crown and root pulp volume versus dentin thickness in terms of PMI determination. The study involved 60 female Wistar rats, with weights ranging from 270 to 320 g. These rats were grouped into six different post-mortem period categories. Following the animals' sacrifice, they were subjected to a natural putrefaction period, with a control group, in the grounds of a sheltered garden. Hemi-mandible samples were then extracted and placed in glass tubes for Micro-CT evaluations, following the progression of putrefaction processes. The pulp volume and dentin thickness were assessed using Micro-CT, and the gathered data underwent statistical analysis. Micro-CT was employed to analyze sixty right mandibular second molar teeth in the hemi-mandible. The crown pulp volume exhibited a reduction in group 6, with a value of 0.239 mm3 after a three-month period of natural putrefaction (p < 0.001). There is statistically differences among groups in case of pairwise comparison (p < 0.05). However, the root pulp volume and dentin thickness variables did not display any statistically significant changes. Despite certain limitations associated with this study, the Micro-CT findings concerning teeth pulp volume can serve as an objective parameter, especially for late postmortem investigations and the estimation of time of death.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"71-79"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140186837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanical trauma in children and adolescents in Berlin. 柏林儿童和青少年的机械创伤。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-04-16 DOI: 10.1007/s12024-024-00814-7

Christine Eimer, Claas Buschmann, Jonas Deeken, Thoralf Kerner

{"title":"Mechanical trauma in children and adolescents in Berlin.","authors":"Christine Eimer, Claas Buschmann, Jonas Deeken, Thoralf Kerner","doi":"10.1007/s12024-024-00814-7","DOIUrl":"10.1007/s12024-024-00814-7","url":null,"abstract":"Management of severe pediatric trauma remains challenging. Injury patterns vary according to patient age and trauma mechanism. This study analyzes trauma mechanisms in deceased pediatric patients. Fatal pediatric trauma cases aged 0-18 years who underwent forensic autopsy in the Federal State of Berlin, Germany, between 2008 until 2018 were enrolled in this retrospective study. Autopsy protocols were analyzed regarding demographic characteristics, trauma mechanisms, injury patterns, resuscitation measures, survival times as well as place, and cause of death. 71 patients (73% male) were included. Traffic accidents (40%) were the leading cause of trauma, followed by falls from height > 3 m (32%), railway accidents (13%), third party violence (11%) and other causes (4%). While children under 14 years of age died mostly due to traumatic brain injury (59%), polytrauma was the leading cause of death in patients > 14 years (55%). Other causes of death were hemorrhage (9%), thoracic trauma (1%) or other (10%). A suicidal background was proven in 24%. In the age group of > 14 years, 40% of all mortalities were suicides. Cardiopulmonary resuscitation was carried out in 39% of all patients. 42% of the patients died at the scene. Children between 0 and 14 years of age died most frequently from traumatic brain injury. In adolescents between 14 and 18 years of age, polytrauma was mostly the cause of death with a high coincidence of suicidal deaths. The frequency of fatal traffic accidents and suicides shows the need to improve accident and suicide prevention for children and adolescents.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"115-122"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140854421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tension hydrothorax complicating syringopleural shunt for post-traumatic syringomyelia. 外伤后鞘膜积液分流术并发的张力性水胸。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-07-26 DOI: 10.1007/s12024-024-00827-2

Michael Duffy, Yeliena Baber, Chris O'Donnell

引用次数: 0

The application of vibrational spectroscopy in forensic analysis of biological evidence. 振动光谱法在生物证据法医分析中的应用。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-08-24 DOI: 10.1007/s12024-024-00866-9

Zehua Fan, Ji Zhang, Chunling Ma, Bin Cong, Ping Huang

{"title":"The application of vibrational spectroscopy in forensic analysis of biological evidence.","authors":"Zehua Fan, Ji Zhang, Chunling Ma, Bin Cong, Ping Huang","doi":"10.1007/s12024-024-00866-9","DOIUrl":"10.1007/s12024-024-00866-9","url":null,"abstract":"Vibrational spectroscopy is a powerful analytical domain, within which Fourier transform infrared spectroscopy (FTIR) and Raman spectroscopy stand as exemplars, offering high chemical specificity and sensitivity. These methodologies have been instrumental in the characterization of chemical compounds for an extensive period. They are particularly adept at the identification and analysis of minute sample quantities. Both FTIR and Raman spectroscopy are proficient in elucidating small liquid samples and detecting nuanced molecular alterations. The application of chemometrics further augments their analytical prowess. Currently, these techniques are in the research phase within forensic medicine and have yet to be broadly implemented in examination and identification processes. Nonetheless, studies have indicated that a combined classification model utilizing FTIR and Raman spectroscopy yields exceptional results for the identification of biological fluid-related information and the determination of causes of death. The objective of this review is to delineate the current research trajectory and potential applications of these two vibrational spectroscopic techniques in the detection of body fluids and the ascertainment of causes of death within the context of forensic medicine.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"406-416"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hereditary thrombophilia as a possible risk factor for severe disease in COVID-19: a case series. 遗传性血栓性疾病可能是 COVID-19 严重疾病的危险因素：病例系列。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-09-27 DOI: 10.1007/s12024-024-00879-4

Jonathan Tse, Julita Gongolli, Joseph A Prahlow

{"title":"Hereditary thrombophilia as a possible risk factor for severe disease in COVID-19: a case series.","authors":"Jonathan Tse, Julita Gongolli, Joseph A Prahlow","doi":"10.1007/s12024-024-00879-4","DOIUrl":"10.1007/s12024-024-00879-4","url":null,"abstract":"Purpose: The risk factors that modulate one's susceptibility for severe COVID-19 have been well documented. Despite this, hypercoagulability remains an often overlooked risk factor for severe disease for COVID-19. Because COVID-19 infection is a risk factor for hypercoagulability, a reasonable presumption/hypothesis is that patients with hereditary thrombophilia would be at a higher risk of thrombotic complications associated with COVID-19 infection.Methods: This case report details two cases where previously unknown hereditary thrombophilias likely contributed to the mortality of COVID-19 patients.Results: The first COVID-19 patient's cause of death was pulmonary thromboemboli from deep vein thrombosis due to heterozygous MTHFR C667T and heterozygous PAI-1 4G/5G mutations. The second COVID-19 patient's cause of death was an acute myocardial infarct due to a coronary artery thrombosis in the setting of heterozygous MTHFR A1298C and homozygous PAI-1 4G/5G mutations. In each case, COVID-19 infection was also considered contributory to death.Conclusion: The occurrence of these fatal thrombotic events in COVID-19 patients with hereditary thrombophilias raises questions as to whether this combination of thrombotic risk factors for hypercoagulability may have placed patients at a significant enough risk to experience these fatal thrombotic complications. Thus, while not sufficient alone to prove that SARS-CoV-2 patients with hereditary thrombophilias are at increased risk for thrombotic complications, these two cases indicate that further investigation is warranted into elucidating the relationship between thrombotic risk factors as it may identify an additional high-risk medical condition for COVID-19 and have important diagnostic and therapeutic ramifications.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"260-266"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Death in a bathtub of an adolescent with neurofibromatosis type 2 exhibiting meningioangiomatosis with white matter involvement. 一名患有神经纤维瘤病 2 型、脑膜血管瘤病并累及白质的青少年在浴缸中死亡。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-08-24 DOI: 10.1007/s12024-024-00867-8

Kentaro Sakai, Kino Hayashi

{"title":"Death in a bathtub of an adolescent with neurofibromatosis type 2 exhibiting meningioangiomatosis with white matter involvement.","authors":"Kentaro Sakai, Kino Hayashi","doi":"10.1007/s12024-024-00867-8","DOIUrl":"10.1007/s12024-024-00867-8","url":null,"abstract":"Neurofibromatosis type 2 (NF2) is a neurocutaneous syndrome characterized by the development of multiple benign tumors, including vestibular schwannomas and meningiomas, in the nervous system. Seizures are rarely associated with NF2, and the lethality of this condition typically stems from tumor growth and related complications, leaving the incidence of sudden death largely unreported. This report discribes a 16-year-old girl with a history of NF2 and occasional seizures who died unexpectedly in a bathtub. Postmortem examination revealed multiple tumors in the cranial nerves (schwannoma), under the dura mater (meningioma), and in the upper cervical cord (neurofibroma). Typical signs of drowning, such as foam in the airways, were not present. Upon histological examination, meningioangiomatosis (MA) was observed in the cerebellum and the cerebral cortex, specifically in the frontal lobe, temporal lobe, and insula. The MA extended into the white matter, exhibiting severe perivascular fibrosis and cystic dilatation of perivascular spaces in the frontal lobe and cerebellum. Additionally, glial microhamartomas were detected both around and separate from the MA. These autopsy findings suggest that sudden unexpected death in epilepsy (SUDEP) was the cause of death rather than drowning. Moreover, while NF2-associated MA is typically asymptomatic, unlike sporadic MA, which commonly presents with seizures, the spread of MA into the white matter is unusual in an NF2 patient. Therefore, MA with the white matter involvement could have been a factor causing the seizures and the occurrence of SUDEP in this NF2 patient.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"283-289"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Death following cylindrical battery ingestion associated with toxic manganese levels. 摄入圆柱形电池后死亡，与有毒锰含量有关。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-06-29 DOI: 10.1007/s12024-024-00854-z

Eulalie Pefferkorn, Bruno Clément, Agathe Bascou, Céline Guilbeau-Frugier, Norbert Telmon, Frédéric Savall, Fabrice Dedouit

{"title":"Death following cylindrical battery ingestion associated with toxic manganese levels.","authors":"Eulalie Pefferkorn, Bruno Clément, Agathe Bascou, Céline Guilbeau-Frugier, Norbert Telmon, Frédéric Savall, Fabrice Dedouit","doi":"10.1007/s12024-024-00854-z","DOIUrl":"10.1007/s12024-024-00854-z","url":null,"abstract":"Cases of battery ingestion are well documented in the scientific literature, especially concerning button cell battery ingestion in children. In this instance, the authors present an atypical case of a young man who voluntarily ingested a cylindrical alkaline battery containing manganese. The patient died approximately a week later, despite not exhibiting any specific symptoms. The battery was found in the cecum during the autopsy, showing deterioration at its positive pole. The cecal mucosa exhibited two ulcerations without perforation. Histological analysis revealed intestinal ischemia in the cecum, with no microscopic lesions in other organs. Toxicology reports indicated high levels of manganese in both cardiac and peripheral blood. Considering all the results from the additional analyses, the experts concluded that the death was likely of multifactorial origin, associated with a toxic blood concentration of manganese. To the best of our knowledge, this is the first recorded death following the ingestion of a cylindrical battery, and the first instance of manganese intoxication resulting from the ingestion of an alkaline battery. The authors will present the case and provide a literature review to assess the extent to which the presence of manganese may have contributed to the fatality.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"295-301"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141476333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Yemeni genetic structure revealed by the Y chromosome STRs. Y 染色体 STR 揭示的也门遗传结构。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2025-03-01 DOI: 10.1007/s12024-025-00975-z

Khalid Al-Shoba, Nabil Al-Hamadi, Eida Khalaf Almohammed, Sibte Hadi, William Goodwin, Hayder Lazim

{"title":"The Yemeni genetic structure revealed by the Y chromosome STRs.","authors":"Khalid Al-Shoba, Nabil Al-Hamadi, Eida Khalaf Almohammed, Sibte Hadi, William Goodwin, Hayder Lazim","doi":"10.1007/s12024-025-00975-z","DOIUrl":"https://doi.org/10.1007/s12024-025-00975-z","url":null,"abstract":"Yemen, with its rich historical background and strategic geographical position at a major crossroads of trade and migration, offers an ideal setting for exploring population genetics. This study aimed to develop a Y-STR database for a Yemeni population and compare it with existing regional databases in the Middle East. For this investigation, buccal swabs were collected from 128 unrelated males. Genomic DNA was extracted using the QIAamp® DNA Mini Kit, and Y-chromosomal STR profiling was performed with the AmpFℓSTR® Yfiler™ PCR Amplification Kit to generate haplotype data across 17 Y-STR loci. The final dataset exhibited a haplotype diversity of 0.008 and a discrimination capacity of 0.95. Among the STR loci assessed, DYS458 emerged as the most polymorphic, displaying a gene diversity of 0.87 and accounting for the majority of microvariant alleles (62.5%). Additionally, haplogroup analysis using the NevGen haplogroup predictor tool revealed two predominant haplogroups within this Yemeni population: J1a (59.37%) and E1b1b (21.09%). Comparisons with 52 Middle Eastern populations (encompassing 5,568 individuals) through multidimensional scaling, phylogenetic assessments, admixture analyses, and ancestry variability evaluations collectively underscore the unique genetic landscape of Yemen. Overall, the combined findings indicate evidence of a potential founder effect within the Yemeni population. Taken together, these data not only enrich the forensic and population genetic understanding of the region but also emphasize Yemen's pivotal role in illuminating migration and demographic processes in the Middle East.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0