Forensic Science, Medicine and Pathology最新文献_第10页

Histiocytoid cardiomyopathy presenting as sudden death in an 18-month-old infant. 一名18个月大婴儿的组织细胞样心肌病表现为猝死。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-09-01 Epub Date: 2023-10-13 DOI: 10.1007/s12024-023-00730-2

Jacob Foster, Sarah Parsons

{"title":"Histiocytoid cardiomyopathy presenting as sudden death in an 18-month-old infant.","authors":"Jacob Foster, Sarah Parsons","doi":"10.1007/s12024-023-00730-2","DOIUrl":"10.1007/s12024-023-00730-2","url":null,"abstract":"Histiocytoid cardiomyopathy (HC) is an arrhythmogenic disorder, usually involving children under two years of age with a strong Caucasian and female predominance. The disease is fatal in the vast majority and diagnosis is nearly always established at autopsy, but this is only possible with adequate myocardial sampling. Meticulous gross and histological examination of the heart in collaboration with a cardiovascular-trained pathologist maximises the opportunity to make specific diagnoses (and therefore rule out the differentials of SIDS, SUDC and child abuse), guide genetic testing, and inform potentially life-saving medical interventions for blood relations. We present a typical HC case presenting as sudden death, without prodrome, in a previously healthy 18-month-old boy. The disease is characterised histologically by discrete groups of enlarged, polygonal histiocyte-like cells with distinct margins and abundant faintly eosinophilic foamy cytoplasm. Cells often contain coarse granules, microvacuoles and irregular, round nuclei. In our case, dysplastic fascicles were predominantly located immediately deep to the endocardium of the left ventricle. We report our own autopsy findings with histological images, and discuss the expected clinical, morphological and ultrastructural features of the disease.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"1117-1120"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41197004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methylamphetamine toxicity and its involvement in death: A retrospective observational study of deaths reported to the Victorian Coroner, Australia. 甲基苯丙胺毒性及其与死亡的关系：澳大利亚维多利亚州验尸官报告的死亡回顾性观察研究。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-09-01 Epub Date: 2023-10-04 DOI: 10.1007/s12024-023-00724-0

Dylan Mantinieks, Melanie Archer, Jennifer Schumann, Olaf H Drummer, Dimitri Gerostamoulos

{"title":"Methylamphetamine toxicity and its involvement in death: A retrospective observational study of deaths reported to the Victorian Coroner, Australia.","authors":"Dylan Mantinieks, Melanie Archer, Jennifer Schumann, Olaf H Drummer, Dimitri Gerostamoulos","doi":"10.1007/s12024-023-00724-0","DOIUrl":"10.1007/s12024-023-00724-0","url":null,"abstract":"A retrospective observational study of Victorian deaths involving MA between 2010 and 2019 was conducted to determine the prevalence and contribution of methylamphetamine (MA) toxicity to death in the absence of other factors. Demographics, autopsy findings, toxicology, and the cause of death were reviewed. Coronial cases were categorized into five groups: deaths due to MA toxicity in the absence of other factors (Group A1); deaths due to MA toxicity in the setting of other potentially contributing factors (Group A2); deaths due to MA toxicity in the setting of significant natural disease (Group B); deaths primarily due to multiple-drug toxicity (Group C); and deaths primarily due to natural causes (Group D). There were 506 deaths involving MA categorized into Group A1 (n = 1, 0.6%), Group A2 (n = 8, 1.6%), Group B (n = 28, 5.5%), Group C (n = 229, 45%), and Group D (n = 240, 47%). Significant natural disease was prevalent among deaths involving MA and mainly concerned forms of cardiovascular disease (n = 277, 55%). The MA concentration in the one death included in Group A1 was 2.1 mg/L. The median MA concentrations of Group A2 (1.6 mg/L) and Group B (0.5 mg/L) were significantly higher than Group C (0.2 mg/L) and Group D (0.2 mg/L). Additionally, many other toxicologically significant drugs were detected and mostly comprised of central nervous system depressants. Deaths due to MA toxicity in the absence of other factors were rare despite the greater availability of crystal MA in the Australian community. The study highlights the interpretative challenges of MA blood concentrations and the continuing harms of this drug in Australia.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"852-862"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41114893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traumatic hemorrhage of the thyroid as a work-related injury: a case report and review of the literature. 工伤导致的甲状腺创伤性出血：病例报告和文献综述。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-09-01 Epub Date: 2023-08-09 DOI: 10.1007/s12024-023-00688-1

Lucia Tattoli, Luca Sussetto, Giancarlo Di Vella

{"title":"Traumatic hemorrhage of the thyroid as a work-related injury: a case report and review of the literature.","authors":"Lucia Tattoli, Luca Sussetto, Giancarlo Di Vella","doi":"10.1007/s12024-023-00688-1","DOIUrl":"10.1007/s12024-023-00688-1","url":null,"abstract":"Traumatic hemorrhage of the thyroid gland resulting from blunt injury to the neck is a very rare event. Particular neck positions can expose the thyroid to trauma, especially in motor vehicle collisions, falls, direct blows, or sport activities. Preexisting conditions such as goiters, adenomas, and cysts can increase the risk of bleeding, reducing the force required to rupture the gland and make the thyroid more prone to injury. The authors report the case of a 53-year-old man who was involved in a fire while working on maintenance of a liquid petroleum gas (LPG)-powered car. He subsequently presented to the emergency department with painful swelling of his right anterior neck with a palpable mass. CT scan showed a right thyroid hemorrhagic cyst. The worker reported that he had jumped into the car trunk to extinguish the fire and covered the gas tank nozzle with his own body to prevent dispersal of the accelerant. In this case, the medico-legal evaluation was useful to delineate between natural and traumatic causes of the injury. Medico-legal assessment is key in understanding the dynamics involved in work-related events to identify any legal responsibilities of the worker or the employer.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"983-989"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9960440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluctuating asymmetry in third molar agenesis as an aid to estimate socioeconomic status. 第三磨牙发育不全的波动不对称作为估算社会经济地位的辅助工具。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-09-01 Epub Date: 2023-09-06 DOI: 10.1007/s12024-023-00706-2

Ana Rita Dinis, Alexandra Teixeira, Daniel Pérez-Mongiovi, Inês Morais Caldas

{"title":"Fluctuating asymmetry in third molar agenesis as an aid to estimate socioeconomic status.","authors":"Ana Rita Dinis, Alexandra Teixeira, Daniel Pérez-Mongiovi, Inês Morais Caldas","doi":"10.1007/s12024-023-00706-2","DOIUrl":"10.1007/s12024-023-00706-2","url":null,"abstract":"Traditionally, dental identification techniques are used to establish identity or assist in reconstructing an individual's biological profile. However, other aspects of identity, namely socioeconomic status (SES), can be estimated through teeth. This work aims to evaluate the influence of SES on third molar agenesis in a Portuguese population. X-rays from 448 subjects (223 belonging to a high and 225 to a low socioeconomic status) were assessed and demographic data (age, sex) and dental history were registered. Frequencies and associations between the variables were analyzed using the chi-square test. For each group, differences between third molar agenesis were studied using the Wilcoxon test. The significance level was 5%. X-rays displaying at least one agenesis were more common in females (in both SES groups). Differences between socioeconomic status were found in female subjects' upper right and lower left third molars, with a higher frequency of agenesis in the lower SES group. Agenesis of lower third molars displayed fluctuant asymmetry in both groups, whereas agenesis of upper third molars was also present in the lower SES group. These results suggest that socioeconomic status can affect third molar agenesis prevalence, and fluctuant asymmetry seems more prevalent in the lower SES, as it affects all third molars.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"831-837"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10218857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of sex and sexual dimorphism in children from Tamilnadu, India through odontometrics in primary dentition - a cross sectional study with discriminant function analysis. 印度塔米尔纳杜儿童性别和两性异形的评估——通过初级牙列的齿形测量——一项具有判别函数分析的横断面研究。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-09-01 Epub Date: 2023-10-23 DOI: 10.1007/s12024-023-00734-y

Mohan Thirumal, Harikrishnan Prasad, Muthusamy Rajmohan, Kenniyankumar SriChinthu, Perumal Prema, Sivanandhan Shanmuganathan

{"title":"Assessment of sex and sexual dimorphism in children from Tamilnadu, India through odontometrics in primary dentition - a cross sectional study with discriminant function analysis.","authors":"Mohan Thirumal, Harikrishnan Prasad, Muthusamy Rajmohan, Kenniyankumar SriChinthu, Perumal Prema, Sivanandhan Shanmuganathan","doi":"10.1007/s12024-023-00734-y","DOIUrl":"10.1007/s12024-023-00734-y","url":null,"abstract":"One of the crucial steps in the process of identification of human remains is sex determination of an unknown individual. Sex can be determined using the human skeleton, especially by examining the pelvis and skull. Odontometric analysis and assessment of sexual dimorphism of the human dentition has been less investigated, especially in primary dentition. Hence, this research was designed to verify the presence of sexual dimorphism through odontometric approach in paediatric population of Tamil Nadu, India. The present study was performed on 229 females and 244 males between 3 and 6 years of age. Linear measurements such as maximum mesio distal width, maximum bucco lingual width and clinical crown length were measured in all the primary teeth. Statistical analysis was performed using the Statistical Package for Social Science version 20.0 software (SPSS Inc., Chicago, IL, USA). Mann-Whitney-U test was used to check the statistical significance of the differences observed between males and females. Six equations were derived by discriminant function analysis for practical use. Sexual dimorphism existed in odontometric parameters of primary dentition. The maximum sexual dimorphism was observed in maximum bucco lingual width of 51 and maximum bucco lingual width of 75. The equations derived using discriminant function analysis yielded a jackknife accuracy ranging between 87.5% and 99.8%. These equations may be used to assess the sex from the children of Tamil Nadu, India.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"785-792"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49689590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of ethyl glucuronide in hair and self-reported alcohol consumption in university students. 头发中乙基葡糖苷酸的测定和大学生自我报告的饮酒量。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-09-01 Epub Date: 2023-10-05 DOI: 10.1007/s12024-023-00727-x

Jennifer P Pascali, Arianna Giorgetti, Guido Pelletti, Luca Morini, Susan Mohamed, Marta Barbaresi, Rossana Cecchi, Susi Pelotti, Paolo Fais

{"title":"Determination of ethyl glucuronide in hair and self-reported alcohol consumption in university students.","authors":"Jennifer P Pascali, Arianna Giorgetti, Guido Pelletti, Luca Morini, Susan Mohamed, Marta Barbaresi, Rossana Cecchi, Susi Pelotti, Paolo Fais","doi":"10.1007/s12024-023-00727-x","DOIUrl":"10.1007/s12024-023-00727-x","url":null,"abstract":"Young individuals constitute an intriguing population, as their drinking habits are notably shaped by their perception of their peers' alcohol consumption. Nonetheless, excessive alcohol intake can have detrimental effects on academic performance, interpersonal relationships, and the risk and severity of accidents. This study reported the first data involving students enrolled from three universities on a voluntary basis for alcohol consumption evaluation. Alcohol consumption was assessed through questionnaires and EtG quantification in hair (hEtG) carried out by liquid chromatography-mass spectrometry (LC-MS/MS) analysis after a solid-phase extraction (SPE) purification step. The results of our study demonstrated that 77.1% of samples tested negative for hEtG or displayed hEtG ≤ 5 pg/mg. Particularly, the student population was not characterized by samples with hEtG indicative of chronic excessive consumption (hEtG ≥ 30 pg/mg). No significant association was identified between biological sex, among the degree course/the year attended, nor in relation to BMI or smoking/coffee consumption. Among the obtained results, it was worth noting that the comparison of self-reporting abstinence from tobacco and coffee accounted for 65.3% and 16.7%, respectively, while only 2.8% of the total declared abstinence from alcohol. The current study has uncovered a significant level of interest among students in this analysis and its interpretation. This suggests that implementing public health promotion activities within a university setting could be beneficial.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":"769-777"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41147829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of the Kvaal method to CBCT reconstructed panoramic images for age estimation. 将 Kvaal 方法应用于 CBCT 重建全景图像的年龄估计。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-09-01 Epub Date: 2024-01-25 DOI: 10.1007/s12024-024-00783-x

Hatice Çelik, Mehmet Ali Kılıçarslan, Hatice Boyacioglu, Burak Bilecen

引用次数: 0

More on: 'the role of restraint in fatal excited delirium syndrome'. 更多信息束缚在致命性兴奋性谵妄综合征中的作用"。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-09-01 Epub Date: 2023-12-12 DOI: 10.1007/s12024-023-00722-2

Hans H de Boer, Judith Fronczek, Melanie S Archer

引用次数: 0

The impact of SARS-Co-V pandemic on violence against children: one institution's experience. SARS-Co-V 大流行对暴力侵害儿童行为的影响：一个机构的经验。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-30 DOI: 10.1007/s12024-024-00890-9

Francesco Lupariello, Lucia Tattoli, Giuliana Mattioda, Barbara Lauria, Sonia Aguzzi, Sara Simona Racalbuto, Emanuele Castagno, Claudia Bondone

{"title":"The impact of SARS-Co-V pandemic on violence against children: one institution's experience.","authors":"Francesco Lupariello, Lucia Tattoli, Giuliana Mattioda, Barbara Lauria, Sonia Aguzzi, Sara Simona Racalbuto, Emanuele Castagno, Claudia Bondone","doi":"10.1007/s12024-024-00890-9","DOIUrl":"https://doi.org/10.1007/s12024-024-00890-9","url":null,"abstract":"Violence against children (VAC) is a global issue due to its biological, psychological, and social effects. Research in this field is valuable for understanding unknown aspects of VAC and for defining updated intervention strategies. Until now, there have been no clear indications about the possible effects of the SARS-CoV-2 pandemic on VAC. In this study, the authors compared quantitative and qualitative variables of pre-pandemic and pandemic cases evaluated at an Italian center specialized in VAC. The aims were to determine if the cases referred for VAC changed during the pandemic and if there were statistically significant differences in variables' distributions between pre-pandemic and pandemic periods. The referrals during the first 13 months of the 2020 SARS-CoV-2 pandemic were compared to cases referred over 13 months (2018-2019) to the same center. The analysis showed no statistical differences between age distributions and most qualitative variables. A decrease in the number of cases was observed. The comparison of frequency distributions of most variables between pre and post-pandemic samples did not differ. The most important result of the analysis is that the volume of observed VAC cases decreased during the pandemic period, confirming the indications of the scientific literature. It could not be excluded that the decrease was due to the negative impact of the pandemic on the child protection system. The above data could help develop innovative prevention tools and corrective intervention programs for future emergencies.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142106092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The polychromatism of postmortem cerebrospinal fluid. 死后脑脊液的多色性。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-30 DOI: 10.1007/s12024-024-00887-4

S Trella, C Reinert, H Heinsen, U Preiß, C M Monoranu, J Zwirner, B Ondruschka, M Bohnert, S Bohnert

{"title":"The polychromatism of postmortem cerebrospinal fluid.","authors":"S Trella, C Reinert, H Heinsen, U Preiß, C M Monoranu, J Zwirner, B Ondruschka, M Bohnert, S Bohnert","doi":"10.1007/s12024-024-00887-4","DOIUrl":"https://doi.org/10.1007/s12024-024-00887-4","url":null,"abstract":"Based on the assumption that postmortem cerebrospinal fluid (CSF) is contaminated depending on the chosen sampling technique in the forensic setting resulting in bloody or at least hemolytic CSF samples, we systematically documented a total of 183 postmortem CSF samples. These samples were all assessed for their quality and color, regardless of the cause of death or the postmortem interval. The investigations were carried out through subjective assessment of color and turbidity, as well as objective measurements of the optical density (OD) of the CSF supernatants after centrifugation of each sample, with standardized photographic documentation. The observations revealed that in 28 cases the CSF was absolutely (crystal-) clear and transparent. Most of our samples showed color changes ranging from xanthrochromic to rose. Intensive staining of the supernatants was only found in a small proportion of the examined collective. We found that postmortem CSF has no uniform appearance but rather a diverse range of color spectra, and the color, as well as the OD of the CSF, correlates significantly with the postmortem interval (p < 0.001) when sampled using the proposed standard procedure.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142106093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0