Forensic Science, Medicine and Pathology最新文献_第10页

Death in a bathtub of an adolescent with neurofibromatosis type 2 exhibiting meningioangiomatosis with white matter involvement. 一名患有神经纤维瘤病 2 型、脑膜血管瘤病并累及白质的青少年在浴缸中死亡。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-24 DOI: 10.1007/s12024-024-00867-8

Kentaro Sakai, Kino Hayashi

{"title":"Death in a bathtub of an adolescent with neurofibromatosis type 2 exhibiting meningioangiomatosis with white matter involvement.","authors":"Kentaro Sakai, Kino Hayashi","doi":"10.1007/s12024-024-00867-8","DOIUrl":"https://doi.org/10.1007/s12024-024-00867-8","url":null,"abstract":"Neurofibromatosis type 2 (NF2) is a neurocutaneous syndrome characterized by the development of multiple benign tumors, including vestibular schwannomas and meningiomas, in the nervous system. Seizures are rarely associated with NF2, and the lethality of this condition typically stems from tumor growth and related complications, leaving the incidence of sudden death largely unreported. This report discribes a 16-year-old girl with a history of NF2 and occasional seizures who died unexpectedly in a bathtub. Postmortem examination revealed multiple tumors in the cranial nerves (schwannoma), under the dura mater (meningioma), and in the upper cervical cord (neurofibroma). Typical signs of drowning, such as foam in the airways, were not present. Upon histological examination, meningioangiomatosis (MA) was observed in the cerebellum and the cerebral cortex, specifically in the frontal lobe, temporal lobe, and insula. The MA extended into the white matter, exhibiting severe perivascular fibrosis and cystic dilatation of perivascular spaces in the frontal lobe and cerebellum. Additionally, glial microhamartomas were detected both around and separate from the MA. These autopsy findings suggest that sudden unexpected death in epilepsy (SUDEP) was the cause of death rather than drowning. Moreover, while NF2-associated MA is typically asymptomatic, unlike sporadic MA, which commonly presents with seizures, the spread of MA into the white matter is unusual in an NF2 patient. Therefore, MA with the white matter involvement could have been a factor causing the seizures and the occurrence of SUDEP in this NF2 patient.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The application of vibrational spectroscopy in forensic analysis of biological evidence. 振动光谱法在生物证据法医分析中的应用。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-24 DOI: 10.1007/s12024-024-00866-9

Zehua Fan, Ji Zhang, Chunling Ma, Bin Cong, Ping Huang

{"title":"The application of vibrational spectroscopy in forensic analysis of biological evidence.","authors":"Zehua Fan, Ji Zhang, Chunling Ma, Bin Cong, Ping Huang","doi":"10.1007/s12024-024-00866-9","DOIUrl":"https://doi.org/10.1007/s12024-024-00866-9","url":null,"abstract":"Vibrational spectroscopy is a powerful analytical domain, within which Fourier transform infrared spectroscopy (FTIR) and Raman spectroscopy stand as exemplars, offering high chemical specificity and sensitivity. These methodologies have been instrumental in the characterization of chemical compounds for an extensive period. They are particularly adept at the identification and analysis of minute sample quantities. Both FTIR and Raman spectroscopy are proficient in elucidating small liquid samples and detecting nuanced molecular alterations. The application of chemometrics further augments their analytical prowess. Currently, these techniques are in the research phase within forensic medicine and have yet to be broadly implemented in examination and identification processes. Nonetheless, studies have indicated that a combined classification model utilizing FTIR and Raman spectroscopy yields exceptional results for the identification of biological fluid-related information and the determination of causes of death. The objective of this review is to delineate the current research trajectory and potential applications of these two vibrational spectroscopic techniques in the detection of body fluids and the ascertainment of causes of death within the context of forensic medicine.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the impact of corrosive acids on human bone integrity in forensic context. 评估腐蚀性酸类在法医学背景下对人体骨骼完整性的影响。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-22 DOI: 10.1007/s12024-024-00861-0

Priyanka Yadav, Nitin Bishariya, Jasbir Lather, S K Dhattarwal, Neelkamal Sharma, Arun Lohhra

{"title":"Assessing the impact of corrosive acids on human bone integrity in forensic context.","authors":"Priyanka Yadav, Nitin Bishariya, Jasbir Lather, S K Dhattarwal, Neelkamal Sharma, Arun Lohhra","doi":"10.1007/s12024-024-00861-0","DOIUrl":"https://doi.org/10.1007/s12024-024-00861-0","url":null,"abstract":"Dissolving bodies is a contemporary method of disposing of human remains and has been practiced throughout the years. This research article discussed the impact of readily available corrosive chemicals, such as Hydrochloric acid (HCl), Sulfuric acid (H2SO4), and Expelz™ toilet cleaner, on human bone. Unfortunately, the existing literature on this subject is scarce, with only a few studies conducted on human bones. To address this gap, we conducted an experimental analysis using human sternum bone fragments. These samples were subjected to immersion in different acids, namely HCl and H2SO4, at two concentrations (10% and 37%), and Expelz™ toilet cleaner. This research aims to describe the impact of toilet cleaner, sulphuric acid, and hydrochloric acid on bone tissue deterioration at various time intervals. Further, the morphological alterations weight loss, and cytological analysis of bone tissue residue with various acid concentrations and immersion times (3.5, 9, 24, 36, 48, 60, and 72 h) were analyzed. Among the chemicals examined, it is evident that 37% hydrochloric acid (HCl) and sulfuric acid (H2SO4), regardless of refreshment, exhibit the highest reactivity, resulting in the complete decomposition of hard tissue within a few hours. In contrast, the behaviour of 10% H2SO4 reveals a more intricate degradation process characterized by fluctuations in weight loss. These distinct reactivity profiles under different conditions are crucial in understanding the potential for rapid weight loss, signifying high reactivity and more gradual weight loss, indicating a faster decomposition rate. Notably, refreshment of the solution enhanced the reactivity of both HCl and H2SO4.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urgent public health concerns due to rising violence and inadequate cadaver management in ecuador. 厄瓜多尔日益严重的暴力事件和尸体管理不善引发了紧迫的公共卫生问题。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-21 DOI: 10.1007/s12024-024-00878-5

Esteban Ortiz-Prado, Juan S Izquierdo-Condoy, Jorge Vasconez-Gonzalez, Sebastian Barona

引用次数: 0

Cardiovascular-related death in infancy and childhood: a clinicopathological study of two referral institutions in England. 婴幼儿时期与心血管相关的死亡：英国两家转诊机构的临床病理学研究。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-21 DOI: 10.1007/s12024-024-00884-7

Marta C Cohen

引用次数: 0

Visualization of left common carotid artery injury by glass using postmortem virtual angioscopy. 利用死后虚拟血管造影术观察玻璃造成的左侧颈总动脉损伤。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-20 DOI: 10.1007/s12024-024-00883-8

Haruki Fukuda, Rieko Kubo, Miyuki Shiraishi, Hiroyuki Tokue, Akira Hayakawa, Rie Sano, Yoshihiko Kominato

引用次数: 0

Positive identification through comparative dental analysis in mass disaster: a systematic review and meta-analysis. 通过大规模灾难中的牙科对比分析进行积极识别：系统回顾和荟萃分析。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-19 DOI: 10.1007/s12024-024-00876-7

Rizky Merdietio Boedi, Nikolaos Angelakopoulos, Emilio Nuzzolese, Hemlata Pandey, Scheila Mânica, Ademir Franco

{"title":"Positive identification through comparative dental analysis in mass disaster: a systematic review and meta-analysis.","authors":"Rizky Merdietio Boedi, Nikolaos Angelakopoulos, Emilio Nuzzolese, Hemlata Pandey, Scheila Mânica, Ademir Franco","doi":"10.1007/s12024-024-00876-7","DOIUrl":"https://doi.org/10.1007/s12024-024-00876-7","url":null,"abstract":"Purpose: The study aimed to assess the probability of achieving positive identification through comparative dental analysis (CDA) and to determine the factors that influence its success rate in mass disaster scenarios.Methods: An electronic literature search was conducted across six databases for observational studies that reported both the total number of mass disaster victims and the count of victims identified through CDA alone. A random-effect meta-analysis, using the proportion of victims identified with CDA as the effect size, was conducted alongside subgroup analyses based on the type of disaster (natural or non-natural), the disaster classification (open or closed), and the geographical region (i.e., Europe, Asia).Results: The search yielded 3133 entries, out of which 32 studies were deemed eligible. Most of the studies (96.8%) presented a low risk of bias. The meta-analysis revealed a mean weighted-proportion probability of 0.32, indicating that forensic odontology could identify about one-third of the victims in a mass disaster. The probability of comparative dental identification was three times higher in closed mass disasters compared to open disasters (p < 0.05) and was higher in mass disasters occurring in North America and Europe compared to other regions (p < 0.05).Conclusion: The current result suggested that CDA can identify approximately 32% of a victim in a hypothetical scenario, emphasizing the integral role of teeth and forensic odontology in victim identification framework.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postmortem biochemistry of GFAP, NSE and S100B in cerebrospinal fluid and in vitreous humor for estimation of postmortem interval: a pilot study. 通过脑脊液和玻璃体中的 GFAP、NSE 和 S100B 的尸检生化指标估算死后间隔期：一项试点研究。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-15 DOI: 10.1007/s12024-024-00874-9

Rossana Cecchi, Jessika Camatti, Maria Laura Schirripa, Monica Ragona, Silvana Pinelli, Nicola Cucurachi

{"title":"Postmortem biochemistry of GFAP, NSE and S100B in cerebrospinal fluid and in vitreous humor for estimation of postmortem interval: a pilot study.","authors":"Rossana Cecchi, Jessika Camatti, Maria Laura Schirripa, Monica Ragona, Silvana Pinelli, Nicola Cucurachi","doi":"10.1007/s12024-024-00874-9","DOIUrl":"https://doi.org/10.1007/s12024-024-00874-9","url":null,"abstract":"Postmortem interval (PMI) is a challenging issue in forensic practice. Although postmortem biomarkers of traumatic brain injury (TBI) are recognised as an emerging resource for PMI estimation, their role remains controversial. This study aims to evaluate postmortem concentrations of three TBI biomarkers (GFAP, NSE and S100B) in two matrices (cerebrospinal fluid and vitreous humor), in order to find out if these markers could be adopted in PMI estimation. Thirty-five deceased individuals with known PMI who underwent forensic autopsy at the University of Parma were examined. Matrices were collected during autopsy, then biomarker concentrations were determined through the enzyme-linked immunosorbent assay. Statistical significance of the data in relation to PMI was studied. The correlation of biomarkers with PMI, examined with samples divided into six groups according to the number of days elapsed since death, was not statistically significant, although S100B in cerebrospinal fluid showed an increasing trend in cases from 1 to 5 days of PMI. Comparison between cases with 1 day of PMI and those with 2 or more days of PMI showed a statistically significant correlation for GFAP and NSE in cerebrospinal fluid. GFAP and NSE in cerebrospinal fluid represent appropriate biomarkers in PMI estimation to distinguish cases with one day of PMI from those with two or more days of PMI. The current study was limited by the scarcity of the cohort and the narrow spectrum of cases. Further research is needed to confirm these observations.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141987798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decomposition of partially submerged remains: a study on the reliability of insect colonisation for PMI/PMSI estimation. 部分淹没遗骸的分解：关于昆虫定殖对 PMI/PMSI 估算的可靠性的研究。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-14 DOI: 10.1007/s12024-024-00871-y

S K Bray, X A Conlan, M L Harvey

{"title":"Decomposition of partially submerged remains: a study on the reliability of insect colonisation for PMI/PMSI estimation.","authors":"S K Bray, X A Conlan, M L Harvey","doi":"10.1007/s12024-024-00871-y","DOIUrl":"https://doi.org/10.1007/s12024-024-00871-y","url":null,"abstract":"The terrestrial decomposition of remains and associated insect colonisation have been highly researched, and recently studies have expanded to investigate the aquatic decomposition of remains. However, there are instances where remains may experience both terrestrial and aquatic conditions simultaneously due to partial submersion in tidal areas, or influx or efflux of water caused by flood or drought. Decomposition and post-mortem interval (PMI) research to date has focused on remains wholly exposed to either terrestrial or aquatic environments, with limited consideration of dual simultaneous exposure. This study was conducted in artificial lentic environments to ascertain how simultaneous zones of terrestrial and aquatic environments on a single body may impact decomposition. Three trials were completed over a period of 12 months, with each trial consisting of 12 stillborn piglets; three partially submerged head exposed, three partially submerged abdomen exposed, three fully submerged aquatic controls and three terrestrial controls. Decomposition stage and rate were inferred from physical characteristics and insect activity. The decomposition rate of the exposed region of each piglet was significantly faster than the submerged region. The exposed zone of each was colonised by insects and reached skeletonization, whereas the submerged zone without orifice exposure had no insect activity and had a significantly slower decomposition rate. This indicated the ability to utilise terrestrial entomological approaches to estimate a minimum PMI for the exposed portion of the remains. However, without the ability to determine the amount of time the remains may have been submerged for, this estimation represents only a minimum PMSI, with the possibility the remains were submerged for a period of time without insect access and colonisation.","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accident or abuse? Differential diagnosis of contact burns from radiators/heaters in children. 意外还是虐待？儿童接触暖气片/取暖器烧伤的鉴别诊断。

IF 1.5 4区医学

Forensic Science, Medicine and Pathology Pub Date : 2024-08-13 DOI: 10.1007/s12024-024-00875-8

A Amadasi, C Schönfeld, S Etzold

引用次数: 0