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Sulfide: Quinone Oxidoreductase Regulates Mitochondrial Supersulfide Metabolism, Bioenergetics, and Longevity in Eukaryotes 硫化物：醌氧化还原酶调节真核生物线粒体超硫化物代谢、生物能量学和寿命
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.100
Masanobu Morita, Akira Nishimura, Tetsuro Matsunaga, Tomoaki Ida, Seiryo Ogata, Minkyung Jung, Uladzimir Barayeu, Motohiro Nishida, Hozumi Motohashi, Takaaki Akaike
{"title":"Sulfide: Quinone Oxidoreductase Regulates Mitochondrial Supersulfide Metabolism, Bioenergetics, and Longevity in Eukaryotes","authors":"Masanobu Morita, Akira Nishimura, Tetsuro Matsunaga, Tomoaki Ida, Seiryo Ogata, Minkyung Jung, Uladzimir Barayeu, Motohiro Nishida, Hozumi Motohashi, Takaaki Akaike","doi":"10.1016/j.freeradbiomed.2026.08.100","DOIUrl":"10.1016/j.freeradbiomed.2026.08.100","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S14"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
tRNA and Modification Dependency of Mitochondrial Encoded Genes: Predicting Limits to Translation and Function 线粒体编码基因的tRNA和修饰依赖性：预测翻译和功能的极限
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.056
Nathaniel Beam, Dylan Ehrbar, Thomas J. Begley
{"title":"tRNA and Modification Dependency of Mitochondrial Encoded Genes: Predicting Limits to Translation and Function","authors":"Nathaniel Beam, Dylan Ehrbar, Thomas J. Begley","doi":"10.1016/j.freeradbiomed.2026.08.056","DOIUrl":"10.1016/j.freeradbiomed.2026.08.056","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S1"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
G0S2 Regulates Metabolic Health and Repair Capacity in Aging Human Fibroblasts G0S2调节衰老人成纤维细胞的代谢健康和修复能力
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.057
Ian Bosman, Alexis Paynter, Anneka Blankenship, Mahogany Mcknight, Kami Pearson, Prabhat C. Goswami, Ehab H. Sarsour
{"title":"G0S2 Regulates Metabolic Health and Repair Capacity in Aging Human Fibroblasts","authors":"Ian Bosman, Alexis Paynter, Anneka Blankenship, Mahogany Mcknight, Kami Pearson, Prabhat C. Goswami, Ehab H. Sarsour","doi":"10.1016/j.freeradbiomed.2026.08.057","DOIUrl":"10.1016/j.freeradbiomed.2026.08.057","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S1"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Xanthine Oxidoreductase (XOR), Uric Acid, and Iron Homeostasis: Identifying Redox-Associated Vulnerability in Cancer 黄嘌呤氧化还原酶（XOR）、尿酸和铁稳态：确定癌症中氧化还原相关的易感性
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.071
Quincey G. Miller, Joshua Smolkin, Evan Devallance, E.E. Kelley
{"title":"Xanthine Oxidoreductase (XOR), Uric Acid, and Iron Homeostasis: Identifying Redox-Associated Vulnerability in Cancer","authors":"Quincey G. Miller, Joshua Smolkin, Evan Devallance, E.E. Kelley","doi":"10.1016/j.freeradbiomed.2026.08.071","DOIUrl":"10.1016/j.freeradbiomed.2026.08.071","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S5"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Speciation of Hydrogen Sulfide and Cyclo-Octasulfur: Can We Distinguish Their Biochemical Properties and Cellular Functions? 硫化氢和环八硫的形态：能否区分它们的生化性质和细胞功能？
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.114
Yuri Chida, Tsuyoshi Takata, Minkyung Jung, Tomoaki Ida, Tetsuro Matsunaga, Masanobu Morita, Seiryo Ogata, Hozumi Motohashi, Uladzimir Barayeu, Takaaki Akaike
{"title":"Speciation of Hydrogen Sulfide and Cyclo-Octasulfur: Can We Distinguish Their Biochemical Properties and Cellular Functions?","authors":"Yuri Chida, Tsuyoshi Takata, Minkyung Jung, Tomoaki Ida, Tetsuro Matsunaga, Masanobu Morita, Seiryo Ogata, Hozumi Motohashi, Uladzimir Barayeu, Takaaki Akaike","doi":"10.1016/j.freeradbiomed.2026.08.114","DOIUrl":"10.1016/j.freeradbiomed.2026.08.114","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S18"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cell-Free Analysis of NADPH Dependence and Putative Inhibitors of the NADPH Oxidase DUOX1 NADPH依赖性和推测的NADPH氧化酶DUOX1抑制剂的无细胞分析
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.119
Emily Joyce, Miao-Chong Lin, Kishan Patel, Blessing Ogboo, David Heppner, Albert van der Vliet
{"title":"Cell-Free Analysis of NADPH Dependence and Putative Inhibitors of the NADPH Oxidase DUOX1","authors":"Emily Joyce, Miao-Chong Lin, Kishan Patel, Blessing Ogboo, David Heppner, Albert van der Vliet","doi":"10.1016/j.freeradbiomed.2026.08.119","DOIUrl":"10.1016/j.freeradbiomed.2026.08.119","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S19"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elevated Oxygen Tension Disrupts 8-oxoG–SP1–OGG1-Dependent Endothelial Shear Signaling in CHD-PAH 高氧张力破坏CHD-PAH中8- oxog - sp1 - ogg1依赖的内皮剪切信号
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.123
Santiago Moreno, David Marciano, Amber Eliason, Alexis Hayes
{"title":"Elevated Oxygen Tension Disrupts 8-oxoG–SP1–OGG1-Dependent Endothelial Shear Signaling in CHD-PAH","authors":"Santiago Moreno, David Marciano, Amber Eliason, Alexis Hayes","doi":"10.1016/j.freeradbiomed.2026.08.123","DOIUrl":"10.1016/j.freeradbiomed.2026.08.123","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S20"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NOX5 Drives Changes in Mitochondrial Bioenergetics and Respiratory Supercomplex Organization NOX5驱动线粒体生物能量学和呼吸超复合体组织的变化
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.125
Archi Paul, Samantha Richter, Elizabeth Sweeny
{"title":"NOX5 Drives Changes in Mitochondrial Bioenergetics and Respiratory Supercomplex Organization","authors":"Archi Paul, Samantha Richter, Elizabeth Sweeny","doi":"10.1016/j.freeradbiomed.2026.08.125","DOIUrl":"10.1016/j.freeradbiomed.2026.08.125","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Pages S20-S21"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-Dose Colchicine Targets ALDH2 to Limit Radiation-Induced Carotid Atherosclerosis and Macrophage Senescence-Associated Stemness 低剂量秋水仙碱靶向ALDH2以限制辐射诱导的颈动脉粥样硬化和巨噬细胞衰老相关干枯
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.081
Jun-ichi Abe M.D., Ph.D., Venkata SubrahmanyaKumar Samanthapudi M.S., Weiqing Chen B.S., Ngoc Tuyet Tra M.S., Gilbert F. Mejia D.V.M., Kun Yuan Chu B.S., Jonghae Lee Ph.D., Oanh Hoang M.S., Luis Antonio Rivera M.S., Masaki Osawa Ph.D., Jung Hyun Kim M.D., Shengyu Li Ph.D., Kyung Ae Ko D.V.M., Anilkumar K. Reddy PhD, Silvia Fernanda López Moreno M.D., Stefania Assunto Lenz M.D., Keila Ostos Mendoza M.D., Edgardo G. Sanchez B.S., Anita Deswal M.D., M.P.H., M.B.B.S., Joerg Herrmann M.D., Sivareddy Kotla Ph.D.
{"title":"Low-Dose Colchicine Targets ALDH2 to Limit Radiation-Induced Carotid Atherosclerosis and Macrophage Senescence-Associated Stemness","authors":"Jun-ichi Abe M.D., Ph.D., Venkata SubrahmanyaKumar Samanthapudi M.S., Weiqing Chen B.S., Ngoc Tuyet Tra M.S., Gilbert F. Mejia D.V.M., Kun Yuan Chu B.S., Jonghae Lee Ph.D., Oanh Hoang M.S., Luis Antonio Rivera M.S., Masaki Osawa Ph.D., Jung Hyun Kim M.D., Shengyu Li Ph.D., Kyung Ae Ko D.V.M., Anilkumar K. Reddy PhD, Silvia Fernanda López Moreno M.D., Stefania Assunto Lenz M.D., Keila Ostos Mendoza M.D., Edgardo G. Sanchez B.S., Anita Deswal M.D., M.P.H., M.B.B.S., Joerg Herrmann M.D., Sivareddy Kotla Ph.D.","doi":"10.1016/j.freeradbiomed.2026.08.081","DOIUrl":"10.1016/j.freeradbiomed.2026.08.081","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S8"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PDIA3 Catalyzes MUC5B Disulfide Bond Formation to Promote Pulmonary Fibrosis PDIA3催化MUC5B二硫键形成促进肺纤维化
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.082
Amit Kumar, Sudhir Ghandikota, Joseph Walzer, Mona Ruban, Albert van Der Vliet, David Schwartz, Christopher Evans, Yvonne Janssen-Heininger, Anil Jegga, Vikas Anathy
{"title":"PDIA3 Catalyzes MUC5B Disulfide Bond Formation to Promote Pulmonary Fibrosis","authors":"Amit Kumar, Sudhir Ghandikota, Joseph Walzer, Mona Ruban, Albert van Der Vliet, David Schwartz, Christopher Evans, Yvonne Janssen-Heininger, Anil Jegga, Vikas Anathy","doi":"10.1016/j.freeradbiomed.2026.08.082","DOIUrl":"10.1016/j.freeradbiomed.2026.08.082","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Pages S8-S9"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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