Food Hydrocolloids for Health最新文献

{"title":"Synergistic anticancer enhancement: Sericin nanogels co-delivery of anthocyanin and cancer drugs irinotecan, paclitaxel, and oxaliplatin","authors":"Lei Zhang ,&nbsp;Minglu Hao ,&nbsp;Liang Yao ,&nbsp;Linyuan Xue ,&nbsp;Jingmou Yu ,&nbsp;Dongming Xing ,&nbsp;Pu Chen","doi":"10.1016/j.fhfh.2025.100224","DOIUrl":"10.1016/j.fhfh.2025.100224","url":null,"abstract":"<div><div>In this study, we investigated the potential of a food derivative sericin nanogel-anthocyanin (SNG-C3G) nanocomposite to enhance the anticancer effects of various chemotherapeutic drugs, including irinotecan (IRI), paclitaxel (PTX), and oxaliplatin (OXA), on different cell lines such as HeLa, HSEC, and HEK293T. The SNG-C3G nanocomposites exhibited a uniform spherical morphology, and upon co-encapsulation with either IRI or PTX, the particle size and zeta potential remained relatively consistent, ranging from 24.96 to 29.44 nm and −18.37 to −23.67 mV, respectively. Our findings indicate a marked increase in the anticancer effectiveness when these drugs are combined with the SNG-C3G nanocomposite. Focusing on the interaction with PTX, our proteomic analysis revealed significant changes in cell behavior, including cytoprotective mechanisms, ligand interactions, stress response, and pathways associated with oxidative and metabolic detoxification. Specifically, 13 proteins were upregulated and 10 were downregulated in the SNG-C3G-PTX group compared to the PTX-only group. The strong antioxidant properties of C3G might stand out as a key factor in enhancing these effects. This study suggests the potential for developing new cancer treatment strategies that utilize anthocyanins to boost the effectiveness of traditional chemotherapy protocols.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100224"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144253535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lactobacillus plantarum in high methoxylated pectin-based encapsulation systems supports gut epithelial wound healing in vitro","authors":"Felipe Galvez-Jiron ,&nbsp;Lucas de Freitas Pedrosa ,&nbsp;Luis Silva Lagos ,&nbsp;Xin Tang ,&nbsp;Traudy Wandersleben ,&nbsp;Rodrigo Navia ,&nbsp;Stephan Drusch ,&nbsp;Francisca Acevedo ,&nbsp;Paul de Vos","doi":"10.1016/j.fhfh.2025.100218","DOIUrl":"10.1016/j.fhfh.2025.100218","url":null,"abstract":"<div><div>Wound healing and gut epithelial barrier regulation are crucial for intestinal homeostasis. Effective repair of gut epithelial wounds is crucial for re-establishing the mucosal barrier and resolving inflammation. Pectins, versatile polysaccharides in food, protect sensitive components, such as living bacteria, during gastrointestinal transit and support wound healing by promoting cell proliferation and migration.</div><div>This study investigated the effects of encapsulated <em>Lactobacillus plantarum WCFS1</em> on cell proliferation and migration during epithelial wound healing, using pectin-based beads stabilized with alginate or chitosan. Pectin from lemon, with two degrees of methyl esterification (DM18 and DM88), produced four microbead types. T84 cells were incubated with these beads for 24 hours. The results revealed that cell proliferation and migration were influenced by the bead type, the degree of methyl esterification of the pectin, and the inclusion of <em>L. plantarum</em>. Empty DM88 pectin beads improved cell proliferation while reducing migration tendencies, whereas DM18 beads delayed migration.Beads containing <em>L. plantarum</em> demonstrated different effects: DM18 beads enhanced proliferation without inhibiting migration, while DM88 beads reduced migration. Both empty and <em>L. plantarum</em>-loaded beads decreased CCL20 production. Alginate/pectin beads with <em>L. plantarum</em> increased IL-8, while chitosan/pectin beads delayed migration, reduced CCL20 secretion, and modulated IL-8 levels.</div><div>In conclusion, DM88 pectin beads without <em>L. plantarum</em> and DM18 beads containing <em>L. plantarum</em> supported cell proliferation over migration during epithelial wound healing. These findings suggest that pectin-based encapsulation systems may play a role in promoting gut health, protecting barrier integrity, and delivering therapeutic agents.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100218"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144084373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a self-nanoemulsifying system for the oil extract of Mentha spicata L. and evaluation of its anticancer efficacy in vitro","authors":"F. Morovat ,&nbsp;M. Karimi ,&nbsp;R. Dehdari Vais ,&nbsp;M. Negahdary ,&nbsp;S.A. Dastgheib ,&nbsp;H. Heli","doi":"10.1016/j.fhfh.2025.100222","DOIUrl":"10.1016/j.fhfh.2025.100222","url":null,"abstract":"<div><div>Nanocarriers based on (natural) lipids have been extensively studied to improve the oral bioavailability of anticancer compounds/drugs with poor water solubility. Self-nanoemulsifying drug delivery systems (SNEDDSs) are a route to improve the solubility and bioavailability of lipophilic compounds. In a present study, an SNEDDS using the oil extract of <em>Mentha spicata</em> L. leaves, Tween 80, and PEG 600 (SMO) was prepared. Pseudo-ternary phase diagrams were constructed to find suitable surfactant, solubilizer with the oil extract that form self-nanoemulsion after dilution in water. SMO comprised Tween 80:PEG 600:the oil with 2:3:5 in volume ratios or 2.1:3.4:4.5 in mass ratios. It comprised nanodroplets of 82.5 ± 4.7 nm in diameter and had a stability of &gt;45 days. SMO led to enhanced cytotoxicity of the oil extract with IC-50 values of 1.9 ± 0.1 and 2.0 ± 0.1 mg mL⁻¹ for MDA-MB-231 and MCF-7 cells, respectively. SMO would be applicable for delivery of either water insoluble chemotherapeutic drugs or natural anticancer oils upon more investigations.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100222"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144147172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization and characterization of Kappaphycus alvarezii and κ-carrageenan hydrolysates with potential biomedical applications","authors":"Ika Yustisia ,&nbsp;Marhaen Hardjo ,&nbsp;Hasri ,&nbsp;Wa Ode Naafi Sari ,&nbsp;Kasmiati","doi":"10.1016/j.fhfh.2025.100205","DOIUrl":"10.1016/j.fhfh.2025.100205","url":null,"abstract":"<div><div><em>Kappaphycus alvarezii</em>, a widely cultivated red macroalga, is primarily known as a source of κ-carrageenan (κC), a polysaccharide with potential health benefits. This study optimized the hydrolysis process of K<em>. alvarezii</em> and κC using weak acetic acid under varying conditions of concentration, temperature, and duration. The resulting hydrolysates were characterized and evaluated for their biological activities, including antioxidant properties, α-amylase inhibition, oral sucrose tolerance, cytotoxicity, glucose uptake, and apoptosis gene expression in MCF7 and WiDr cancer cell lines. The optimized conditions—2 M acetic acid at 110 °C for 90 mins—yielded the highest reducing sugar content (31.87 g/L for K<em>. alvarezii</em> and 39.73 g/L for κC). The hydrolysates showed antioxidant activity (IC50: 2.58 mg/mL for K<em>. alvarezii</em> and 4.92 mg/mL for κC), significant α-amylase inhibition, and slightly to moderate toxicity in rats, inducing apoptosis in cancer cells through increased expression of BAX and Caspase 3. <em>In vivo</em> tests further demonstrated the potential of these hydrolysates to modulate blood glucose levels. These findings suggest that K<em>. alvarezii</em> and κC hydrolysates have promising therapeutic applications in antioxidant activity, enzyme inhibition, and cancer treatment, warranting further investigation.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100205"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143437347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beneficial effects of soluble dietary fiber from Dendrocalamus brandisii Munro shoots on high-fat diet-induced metabolic disorders in mice: Impact on liver, adipose tissue, and intestinal health","authors":"Mingtian Tian ,&nbsp;Jiahong Dong ,&nbsp;Yuhong Guo ,&nbsp;Yihe Zhao ,&nbsp;Jianxin Cao","doi":"10.1016/j.fhfh.2025.100217","DOIUrl":"10.1016/j.fhfh.2025.100217","url":null,"abstract":"<div><div>Bamboo shoot soluble dietary fiber (DBS-SDF) has numerous health-promoting benefits, but its protective effects and potential mechanism against obesity-related metabolic disorders remain unclear. The effects of DBS-SDF on metabolic disorders induced by a high-fat diet (HFD) in mice was studied. Supplementation with DBS-SDF alleviated the development of HFD-induced obesity and related symptoms by lowering serum lipid levels, preventing lipid degeneration, and modulating the expression levels of genes related to lipid synthesis and decomposition in the liver. At the same time, DBS-SDF reversed the enlargement of white adipose cells, prevented the whitening of brown adipose tissue, and activated fat browning to improve energy balance. In addition, DBS-SDF reshaped the structure of the gut microbiota, significantly reducing the ratio of Firmicutes/Bacteroidetes, promoting the proliferation of SCFA producing bacteria <em>Ligilactobacillus</em>, unclassified_<em>Muribaculaceae</em>, and <em>Lachnospiraceae</em>_NK4A136_group, while inhibiting harmful bacterial populations such as <em>Faecalibaculum</em> and <em>Desulfovibrio</em>. These effects are related to the enhancement of the intestinal barrier, such as upregulation of Intectin expression, increased secretion of mucin MUC2, and increased expression of tight junction proteins. Spearman correlation analysis revealed significant associations between obesity related indicators, intestinal barrier, and gut microbiota, emphasizing the improvement effect of DBS-SDF on metabolic disorders through a healthy gut microenvironment. These findings indicate that DBS-SDF has enormous potential in the development of prebiotics or functional foods.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100217"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of different models for analyzing starch dynamic hydrolysis","authors":"Yuzhi Han ,&nbsp;Cunxu Wei","doi":"10.1016/j.fhfh.2025.100200","DOIUrl":"10.1016/j.fhfh.2025.100200","url":null,"abstract":"<div><div>Dynamic hydrolysis is an important property of starch, and hydrolysis parameters can provide information on starch qualities and applications in food and nonfood industries. The modified Michaelis-Menten equation (MME), single first-order kinetics equation (SKE), log of slope linear equation (LOSLE), or combination of parallel and sequential first-order kinetics equation (CPSKE) models are usually used to fit the dynamic hydrolysis data. In this study, the hydrolysis profiles of five starches were fitted by the MME, SKE, LOSLE and CPSKE models. The fits of the different models were evaluated using the sum of squares of residuals (SUMSQ), the fitting determination coefficient (R²), and the differences between the experimental and fitted data. When tested on the five starches, CPSKE model exhibited the best fit, LOSLE model had a better fit than did MME model, and SKE model had the poorest fit among them. Although these models had significantly different fitting qualities, the maximum extent of hydrolysis predicted by the different models was significantly positively correlated. The hydrolysis rate coefficient <em>k</em> fitted by the SKE model was significantly positively correlated with the <em>k</em>₁ fitted by the LOSLE and CPSKE models, but had no significant correlation with <em>k</em>₂ during phase 2 as fitted by the LOSLE and CPSKE models. The <em>k</em>₁ and <em>k</em>₂ values fitted by the LOSLE model were significantly positively correlated with the <em>k</em>₁ and <em>k</em>₂ parameters estimated by CPSKE model, respectively. This study could provide useful information for choosing fitting models for analyzing starch hydrolysis profiles.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100200"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143143007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secretion of inflammatory mediators by human intestinal epithelial cells incubated with gastric digesta of emulsion gels containing capsaicinoids: Implication on gastric irritation","authors":"Nan Luo ,&nbsp;Frances M. Wolber ,&nbsp;Harjinder Singh ,&nbsp;Aiqian Ye","doi":"10.1016/j.fhfh.2025.100212","DOIUrl":"10.1016/j.fhfh.2025.100212","url":null,"abstract":"<div><div>An <em>in vitro</em> method was developed to test gastric irritation by quantifying the secretion of interleukin-8 (IL-8) by human intestinal epithelial cells Caco-2 after incubation with gastric digesta of emulsion gels containing capsaicinoids (CAP) obtained from simulated dynamic gastric digestion. The emulsion gel structure was modified using different emulsifiers: whey proteins versus Tween 80. Results indicate that both the CAP and Tween 80 molecules were proinflammatory to Caco-2 cells and stimulated cells to produce IL-8. Gastric digesta from CAP-loaded Tween 80 emulsion gel stimulated significantly more IL-8 production than CAP-loaded whey protein emulsion gel, possibly because of the presence of Tween 80 and also, because more CAP molecules were released from Tween 80 emulsion gel during gastric digestion. Tween 80 emulsion gel had a loose structure; it was easily broken down into smaller pieces and had large amounts of oil droplet liberation from the protein matrix, which would promote the release of CAP molecules, leading to higher IL-8 production. On the other hand, whey-protein-coated oil droplets had strong connections with surrounding protein matrix and were well protected during gastric digestion; the release of CAP molecules was much less. This study suggests that by modifying the structure of the foods, the gastric digestion behaviour can be modified, which would affect the release behaviour of CAP molecules and influence gastric irritation / inflammation.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100212"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of phenolic extraction method and in vitro bioaccessibility of microencapsulated pigmented rice bran extracts and their antioxidant and anticancer properties","authors":"Rhowell Navarro Tiozon Jr. ,&nbsp;Glenn Vincent P. Ong ,&nbsp;Kristel June D. Sartagoda ,&nbsp;Sheba Mae M. Duque ,&nbsp;Saleh Alseekh ,&nbsp;Aldrin P. Bonto ,&nbsp;Shem Gempesaw Jr. ,&nbsp;Vipin Pratap ,&nbsp;Florencio C. Reginio Jr. ,&nbsp;Jonina Marie J. Tengco ,&nbsp;Christian Seagan ,&nbsp;Joel H G Tolentino ,&nbsp;Dennis Marvin O. Santiago ,&nbsp;Alisdair R. Fernie ,&nbsp;Nese Sreenivasulu","doi":"10.1016/j.fhfh.2025.100221","DOIUrl":"10.1016/j.fhfh.2025.100221","url":null,"abstract":"<div><div>Pigmented paddy rice is rich in a diverse array of phytochemicals that confer notable antioxidant and anticancer properties. However, the stability and bioaccessibility of these bioactive compounds present significant challenges. In this study, 542 brown (including pigmented and non-pigmented) whole grain rice samples were screened for their antioxidant components and capacity, leading to the identification of three superior cultivars: Balatinao variable purple rice, Ketan Hitam variable purple rice, and Kintuman red rice. Using response surface methodology, rice bran extracts from these cultivars were subjected to microencapsulation to stabilize the phytochemicals. Among the microencapsulated rice bran extracts (MRBEs), Ketan Hitam MRBE demonstrated significantly higher total phenolic content (TPC) and antioxidant capacity. This enhancement is likely due to the increased concentrations of isovitexin, luteolin 7-glucoside, and vitexin following microencapsulation. Furthermore, compared to non-encapsulated rice bran extracts, MRBEs exhibited significantly improved anticancer activity against HCT116 (colon) and A549 (lung) cancer cell lines (<em>P</em> &lt; 0.05). Subsequent fractionation of the MRBE allowed for the identification of the most bioactive fractions, which contained metabolites effective against these cancer cell lines. In addition, <em>in vitro</em> bioaccessibility assays revealed a controlled release of 19 targeted phenolic compounds. This release profile was characterized by an initial increase during the gastric digestion phase, followed by a decrease in the intestinal phase. Notably, phenolic compounds such as chlorogenic acid, gallic acid, and vanillin were preserved across the three rice varieties after microencapsulation. These findings underscore the potential of MRBEs as functional food ingredients or supplements, offering improved bioaccessibility of phenolics, enhanced antioxidant properties, and promising anticancer activity. The results support the integration of rice bran extracts into the rice value chain, promoting their use in functional health applications.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100221"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144130942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formulation optimization of orodispersible film containing essential oil from fruits of Zanthoxylum rhetsa (Roxb.) DC. using response surface methodology and evaluation of its antioxidant, and antiglycation activities","authors":"Pimpikar Kanchanadumkerng ,&nbsp;Vilasinee Hirunpanich Sato ,&nbsp;Nattawut Charoenthai ,&nbsp;Thongtham Suksawat ,&nbsp;Pattamapan Lomarat ,&nbsp;Savita Chewchinda","doi":"10.1016/j.fhfh.2025.100220","DOIUrl":"10.1016/j.fhfh.2025.100220","url":null,"abstract":"<div><div>This study aimed to develop an optimal formulation for an orodispersible film containing essential oil from <em>Zanthoxylum rhetsa</em> (ZR film) using response surface methodology with a Box-Behnken design experiment and to evaluate its antioxidant and antiglycation activities. Three independent variables—gelatin (1–3 % w/v), carrageenan (0.5–1.5 % w/v), and essential oil from <em>Z. rhetsa</em> fruits (1–3 % w/v)—were utilized to design a ZR film with desirable characteristics. Dependent variables, including film thickness, moisture content, and disintegration time, were assessed. The optimized formulation contained 1 % w/v gelatin, 0.5 % w/v carrageenan, and 2.6 % w/v essential oil from <em>Z. rhetsa</em> fruits. The optimized ZR film exhibited a thickness of 14.2 ± 2.12 µm, a disintegration time of 6.34 ± 0.53 min, and a moisture content of 3.32 ± 0.56 %. Total phenolic content was 55.3 ± 0.4 mg GAE/g, and ABTS radical scavenging capacity was 0.06 ± 0.02 g TEAC/g. Additionally, the ZR film inhibited the formation of advanced glycation end products (AGEs) by 66.97 ± 0.58 %. This ZR film shows promise as a potential oral healthcare product for managing oxidative stress and glycation-related pathologies.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100220"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144106644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the impact of sodium alginate and xanthan hydrocolloids on the rheological Doogh properties (Iranian dairy drink)","authors":"Samin Rafi Azari ,&nbsp;Mohammad Hojjatoleslamy ,&nbsp;Zeinab E. Mousavi ,&nbsp;Hossein Kiani ,&nbsp;Sayed Mohammad Ali Jalali","doi":"10.1016/j.fhfh.2025.100206","DOIUrl":"10.1016/j.fhfh.2025.100206","url":null,"abstract":"<div><h3>Background</h3><div>Doogh is a traditional Iranian fermented dairy drink that has gained popularity as a low-calorie alternative to soft drinks. The incorporation of hydrocolloids like sodium alginate and xanthan gum may enhance its rheological properties and stability.</div></div><div><h3>Objective</h3><div>This study aims to evaluate the effects of sodium alginate and xanthan gum at varying concentrations (0 %, 0.04 %, 0.07 %, and 0.1 %) on the rheological characteristics of Doogh.</div></div><div><h3>Methods</h3><div>Doogh was prepared by diluting yogurt with water and adding double-crystallized salt, followed by the incorporation of hydrocolloids. Rheological properties were assessed using steady flow and dynamic tests over a 42-day storage period at 48 °C. Key parameters such as apparent viscosity, flow behavior index, and yield stress were measured.</div></div><div><h3>Results</h3><div>The addition of hydrocolloids significantly altered the rheological behavior of Doogh, shifting it from Newtonian to pseudoplastic. The highest apparent viscosity (490.18 Pa·s) was recorded in the 0.1 % hydrocolloid sample, while the control (0 %) exhibited the lowest viscosity (270.38 Pa·s). The flow index (n) values were consistently below 1, indicating non-Newtonian behavior, with the 0.1 % sample demonstrating the strongest shear-thinning effect (n = 0.510). Yield stress increased with hydrocolloid concentration, reaching 2013.608 Pa in the 0.1 % sample compared to 743.135 Pa in the control.</div></div><div><h3>Conclusions</h3><div>The incorporation of sodium alginate and xanthan gum effectively enhances the stability and viscosity of Doogh without adversely affecting its rheological behavior during storage. These findings suggest that hydrocolloids can be beneficial in improving the quality of Doogh as a functional beverage.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100206"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}