Food Hydrocolloids for Health最新文献

{"title":"Rheological properties and visual cohesiveness of soy protein-based formulations without thickening agents in dysphagic management","authors":"Varanya Techasukthavorn ,&nbsp;Jirarat Anuntagool","doi":"10.1016/j.fhfh.2024.100193","DOIUrl":"10.1016/j.fhfh.2024.100193","url":null,"abstract":"<div><div>Thickened fluids, or dysphagic drinks, are commonly prescribed for individuals with swallowing difficulties. They help slow down food bolus in the swallowing process, reducing the risk of choking and aspiration. The main goal of this study was to create a set of high-protein supplement drinks varying in caloric density level. Besides, the study aimed to examine both shear and extensional rheological properties along with visual cohesiveness. Soy protein-based formulations A to F were developed with caloric densities: 1, 1.2, 1.5, 2, 2.5, and 3 kcal/mL, respectively. Each formulation was assessed through the International Dysphagia Diet Standardisation Initiative (IDDSI) flow test, shear and extensional rheological behavior, and visual cohesiveness. All samples exhibited shear-thinning behavior with viscosity increased with higher caloric density. Formulations A and B were classified as low-viscosity liquids, while formulations C, D, E, and F were suitable for extensional flow measurements with extensional properties improving as density increased. Visual cohesiveness, assessed through elongation shape and flow behavior, enhances with formulation concentration. Formulations A and B may require the addition of thickening agents to serve as thickened nutritional supplements for dysphagia management. Formulations C, D, and E were mildly to moderately thick, whereas formulation F, characterized by extremely thick with very high yield stress, may cause multiple swallows. These findings highlight the potential for developing higher-calorie supplements without thickeners as a practical strategy to enhance energy and protein intake in individuals with dysphagia. To ensure safe swallowing, future research should validate these results using in-vitro throat models and clinical studies.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"7 ","pages":"Article 100193"},"PeriodicalIF":4.6,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143143012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increase in blood-transferable linear and cyclic dipeptides in human plasma following ingestion of elastin hydrolysate","authors":"Yu Iwasaki ,&nbsp;Mikako Sato ,&nbsp;Yoshinori Katakura ,&nbsp;Yukihiro Sugawara ,&nbsp;Yasutaka Shigemura","doi":"10.1016/j.fhfh.2024.100188","DOIUrl":"10.1016/j.fhfh.2024.100188","url":null,"abstract":"<div><div>In this study, we analyzed the absorption of linear and cyclic dipeptides containing Gly, Pro, Ala, and Val by human blood following the ingestion of elastin hydrolysate. As in previous studies, Pro-Gly was transferred into blood at the highest concentration (Cmax; 14.63 nmol/mL). Moreover, this is the first study to show that Gly-Pro, Pro-Ala, Gly-Ala, cyclo(Gly-Pro), cyclo(Pro-Ala), cyclo(Pro-Val) and cyclo(Gly-Ala) also increase in blood after the ingestion of elastin hydrolysate. The contents of these cyclic dipeptides, which amounts in elastin hydrolysate is verry small, suggested that elastin digestives may be cyclized during digestion and absorption by human blood following the ingestion of elastin hydrolysate. This study suggested that these blood-transferrable linear and cyclic dipeptides could be candidates for elastin-derived bioactive peptides, and this finding consequently led to the further experiments that has been required for clarifying the bioactivities and mechanisms of beneficial effects of elastin hydrolysate.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"6 ","pages":"Article 100188"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alginate-based microencapsulation enhances antinociceptive and anti-inflammatory activities of Phyllanthus amarus and Phyllanthus muellerianus","authors":"Joy J. Adeyemi ,&nbsp;Abayomi M. Ajayi ,&nbsp;Tolulope O. Ajala","doi":"10.1016/j.fhfh.2024.100190","DOIUrl":"10.1016/j.fhfh.2024.100190","url":null,"abstract":"<div><div><em>Phyllantus amarus</em> and <em>P. muellerianus</em> are herbs reported to possess anti-inflammatory activity. Antinociceptive and anti-inflammatory activities of alginate-based microsphere loaded with extracts of <em>P. amarus</em> and <em>P. muellerianus</em> was here reported. The extract-loaded microspheres were prepared using the ionotropic gelation method. The particle size, swelling index, entrapment efficiency, and FTIR spectroscopy were determined. Antinociceptive and anti-inflammatory activities of extract-loaded microspheres were evaluated in hotplate-induced nociception in mice and carrageenan-induced rat paw oedema, respectively. The physicohemical results showed rigid, free-flowing and spherical microspheres, with particle sizes ranging from 985.977±13.65 to 1232±12.99 µm and entrapment efficiencies of 20.9 ± 0.341 to 45.0 ± 0.002 %. Polymer-drug interaction revealed bands indicating aromatics, alcohols and alkenes. The extract-loaded microspheres showed improved antinociceptive and anti-inflammatory activities when compared to the extracts alone. The sodium alginate-based microspheres loaded with <em>Phyllanthus amarus</em> and <em>Phyllanthus muellerianus</em> extracts showed acceptable physicochemical properties and had improved antinociceptive and anti-inflammatory activity compared to the extracts alone.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"6 ","pages":"Article 100190"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143101117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Enhancing quinoa (Chenopodium quinoa Willd) protein extraction: Alkaline solubilization coupled to isoelectric precipitation effects on structure, digestibility and antinutrients”","authors":"Maria Lilibeth Manzanilla-Valdez ,&nbsp;Christine Boesch ,&nbsp;Cristina Martinez-Villaluenga ,&nbsp;Sarita Montaño ,&nbsp;Alan Javier Hernández-Álvarez","doi":"10.1016/j.fhfh.2024.100191","DOIUrl":"10.1016/j.fhfh.2024.100191","url":null,"abstract":"<div><div>Quinoa (<em>Chenopodium quinoa</em> Willd) has gained popularity as a plant-based protein source due to its high protein content and complete amino acid profile. However, protein extraction methods such as alkaline solubilization coupled to isoelectric precipitation (ASIP), can affect protein structure, digestibility, nutritional quality, and the composition of antinutritional factors. This study aimed to assess the effects of ASIP on the secondary structure, protein quality and antinutritional factors (ANFs) composition from three quinoa varieties. The results showed that quinoa protein isolates exhibited a decrease in random coil structures, while β-turns and β-sheets increased, as indicated by FTIR analysis. <em>In vitro</em> protein digestibility improved after protein extraction, ranging from 82.12% to 84.50%. The amino acid score ranged from 0.67 – 0.88, with Yellow quinoa protein concentrate exhibiting the highest value. Black quinoa protein isolate showed the lowest total oxalate content (105.00 mg/100g), while Red quinoa protein concentrate presented higher levels of phytic acid (2.0 g/100 g), saponins (150.0 mg/g), and total phenolic compounds (161.5 mg GAE/100g). Notably, gluten content decreased in all samples following protein extraction. Despite the presence of certain ANFs in quinoa protein isolates/concentrates, the protein quality of quinoa isolates and concentrates was not adversely affected. In conclusion, the extraction process reduced several ANFs, including lectins, oxalates, and gluten, while enhancing the overall protein quality.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"6 ","pages":"Article 100191"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143101116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Casein and acryl amide complexation and bio-adhesive polymeric nano micelles influence on vortioxetine dissolution, penetration enhancement and in vivo absorption","authors":"Samaa Abdullah ,&nbsp;Nabil A. Alhakamy ,&nbsp;Hatim S. AlKhatib ,&nbsp;Rana Abu Huwaij ,&nbsp;Hadil Alahdal ,&nbsp;Abeer A. Altamimi","doi":"10.1016/j.fhfh.2024.100189","DOIUrl":"10.1016/j.fhfh.2024.100189","url":null,"abstract":"<div><div>Vortioxetine (VTX) is a new atypical antidepressant used to treat major depression and other mental disorders. Due to its low water solubility, oral absorption, and fast metabolism, VTX has been commercially manufactured and sold as a hydrobromide. Long-term VTX hydrobromide therapy is frequently associated with respiratory irritation and digestive dysfunction. Two techniques were developed for dissolution, swelling, adherence, and penetration enhancements. The techniques were the VTX and casein (CAS) complexation using the maximum loading capacity, and VTX-polymeric nano micelle using the “Sandwich Technique”. This study includes the maximum VTX-CAS binding capacity determination, VTX-CAS complex preparation, polymeric nano micelle encapsulating VTX-CAS complex optimizations, physiochemical characterisations, solubility assessment, VTX release analysis, swelling analysis and mucus-penetrating study of the VTX-CAS complex and VTX polymeric nano micelle in comparison to the VTX raw material. The optimum VTX-polymeric nano micelle dissolution, swelling, adherence, and penetration enhancements were supported by the results of 91.10±16.34 nm, +19 mV zeta-potential, structural arrangements, and enhanced amorphic character with the morphology and size distribution (50–100 nm). The VTX-polymeric nano micelle could serve as an oral alternative to the VTX hydrobromide therapy based on the results of the biocompatibility and <em>in vivo</em> absorption studies for the VTX-polymeric nano micellar system.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"6 ","pages":"Article 100189"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional properties and toxicological analysis of nanocellulose-based aerogels loaded with polyphenols from Hyeronima macrocarpa berries","authors":"Andrés Felipe Alzate-Arbeláez ,&nbsp;Farid B. Cortés ,&nbsp;Benjamín A. Rojano","doi":"10.1016/j.fhfh.2024.100187","DOIUrl":"10.1016/j.fhfh.2024.100187","url":null,"abstract":"<div><div>In this study, the nutraceutical properties of ethanolic extract of <em>Hyeronima macrocarpa</em> fruits, immobilized on nanocellulose-based aerogels (NCAG) synthesized from the seeds were studied. Specifically, bioactives with antioxidant properties of the pulp were determined, NCAG and homologs of acetate (NCAG-A) and sulfate (NCAG-S) were obtained, and characterized from the seed, the aerogels loaded with antioxidants were studied to determine the anti-radical activity, digestion patterns, protein oxidation inhibition, and toxicological properties. The berries presented a high anthocyanin content of 1317.4 mg C3G/100 g FW and ORAC value ​​of 12,732 µmol Trolox/100 g FW, which make an important source of antioxidants. The seeds presented cellulose content of 61.4 % with a NC yield of 38.4 %. NCAG and their surface homologs were successfully synthesized and characterized by FTIR, DLS, and TEM finding the characteristic bands of the main functional groups, NC presented particle sizes ranging from 64 to 141 nm, BET analysis showed surface areas of 71.1, 102.3, and 183.5 m²/g for NCAG-A, NCAG, and NCAG-S, respectively, and pore sizes of 36–38 nm called mesopores. NCAG presented the highest capacity to trap reactive oxygen species (106.8 mg catechin Eq./g., 86.5 % OH• trapped, respectively). All samples showed the capacity to delay the oxidation of a protein system in a dose-dependent manner, with IC₅₀ values ​​of 70 mg/L (NCAG), 176.3 mg/L (NCAG-A), and 255.6 mg/L (NCAG-S). <em>In vitro</em> digestion showed that NCAG-S was more efficient in delivering anthocyanins under gastric conditions (bioaccessibility of 59.3 %), and NCAG under duodenal conditions (bioaccessibility of 88.2 %). The differences found in samples for the different functional assays can be explained by the various types of interactions generated between the antioxidant molecules and aerogels, in the various media where the analyses are carried out. The results indicate nanocellulose-based aerogels, synthesized from lignocellulosic residues of <em>H. macrocarpa</em> seeds, proved to be porous matrices capable of carrying bioactive substances, and presented interesting properties for the delivery and conservation of antioxidant molecules such as anthocyanins and other polyphenols, achieving an <em>in vitro</em> protective effect against the oxidation of biomolecules.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"6 ","pages":"Article 100187"},"PeriodicalIF":4.6,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142705817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Encapsulation of yarrow phenolic compounds in lupin protein nanoemulsions increases stability during gastrointestinal transit and delivery in the colon","authors":"María de las Nieves Siles-Sánchez ,&nbsp;Laura Jaime ,&nbsp;Milena Corredig ,&nbsp;Susana Santoyo ,&nbsp;Elena Arranz","doi":"10.1016/j.fhfh.2024.100186","DOIUrl":"10.1016/j.fhfh.2024.100186","url":null,"abstract":"<div><div>This study aimed to assess the behaviour of phenolic compounds from yarrow extract encapsulated in nanoemulsions during <em>in vitro</em> gastrointestinal digestion. Oil-in-water nanoemulsions were developed using grape seed oil and lupin protein (LPI) as oil phase and emulsifier, respectively. The use of 6 % LPI including 1 mg/mL of yarrow extract resulted in nanoemulsions with a homogeneous particle size distribution (200 nm) and an encapsulation efficiency of 85.6 %. During <em>in vitro</em> gastrointestinal digestion, most of the phenolics remained encapsulated, being protected from degradation. The <em>in vitro</em> bioavailability of the encapsulated phenolics was measured using a cell co-culture model (Caco-2/HT-29MTX). In this regard, nanoemulsions did not increase the bioavailability of yarrow phenolics, instead, they promoted their access to the colon. Finally, the antiproliferative activity was determined in Caco-2 cells, observing that the apical fraction inhibited cancer cells, indicating the bioefficacy of the non-absorbed phenolics. Thus, this study underscores the potential of LPI-stabilized nanoemulsions as a vehicle for protecting and delivering yarrow phenolics to the colon.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"6 ","pages":"Article 100186"},"PeriodicalIF":4.6,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pectin oligosaccharides from Citri Reticulatae Pericarpium ‘Chachi’ promote wound healing in HaCaT keratinocytes by enhancing cell proliferation and migration","authors":"Zhongcan Peng ,&nbsp;Shurong Tian ,&nbsp;Depo Yang ,&nbsp;Longping Zhu ,&nbsp;Jianing Zhang ,&nbsp;Wenfeng Li ,&nbsp;Guodong Zheng ,&nbsp;Zhimin Zhao","doi":"10.1016/j.fhfh.2024.100185","DOIUrl":"10.1016/j.fhfh.2024.100185","url":null,"abstract":"<div><div>Citri Reticulatae Pericarpium ‘Chachi’ (<em>Citrus reticulata</em> ‘Chachi’) is a traditional Chinese medicine with dual medicinal and dietary uses. As its main component, pectin exhibited various biological activities. However, research and development on it, especially pectin oligosaccharides, remain limited. In this study, ‘Chachi’ pectin oligosaccharides (CPOS) was extracted and prepared for the first time, resulting in the purification of two oligosaccharide components, CPOS3 and CPOS4. Structural characterization of the predominant oligosaccharide, CPOS3, revealed it to be composed of a backbone α-D-Gal<em>p</em>A-(1→2)-α-L-Rha<em>p</em>-(1→4)-α-D-3-OAc-Gal<em>p</em>A-(1→4)-α-D-Gal<em>p</em>A-(1→4)-α-D-Gal<em>p</em>A and a side chain [→5)-α-L-Ara<em>f</em>-(1→]₄ attached at the C-4 of Rha<em>p</em>. Subsequent experiments have shown that CPOS3 can significantly promote the proliferation and migration of human immortalized keratinocyte cell. Further investigation revealed that it facilitated cell proliferation by stimulating DNA synthesis in the S phase of the cell cycle. Additionally, CPOS3 exhibited good thermal stability and rheological characteristics. Based on the good wound healing activity and favorable physicochemical properties of CPOS3, its prospects in the fields of wound dressings and tissue repair are promising.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"6 ","pages":"Article 100185"},"PeriodicalIF":4.6,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesis of silver nanoparticles from mulberry leaf through hot melt extrusion: Enhanced antioxidant, antibacterial, anti-inflammatory, antidiabetic, and anticancer properties","authors":"Hyun-Bok Kim ,&nbsp;Han-Sol You ,&nbsp;Su-ji Ryu ,&nbsp;Ha-Yeon Lee ,&nbsp;Jong-Suep Baek","doi":"10.1016/j.fhfh.2024.100184","DOIUrl":"10.1016/j.fhfh.2024.100184","url":null,"abstract":"<div><div>In this study, mulberry leaf (ML) extract, along with ML processed by hot melt extrusion (HME) (HML), and ML processed by HME with biopolymer (HMLE), were utilized for the eco-friendly synthesis of silver nanoparticles (AgNPs). The physicochemical properties of AgNPs synthesized from ML, HML, and HMLE extracts were characterized using UV–Vis spectrophotometry, zeta potential analysis, transmission electron microscopy (TEM), dynamic light scattering (DLS), energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). HME processing enhanced the active ingredients in the ML extract and increased the reduction efficiency of Ag ions. In the ABTS radical scavenging activity assay, AgNPs synthesized from HMLE (F3) exhibited the highest antioxidant activity with the lowest IC₅₀ value. F3 also demonstrated the lowest minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against <em>Escherichia coli</em> and <em>Staphylococcus aureus</em>. In the disk diffusion test, F3 showed the largest zone of inhibition, indicating the highest antimicrobial activity. In the anti-inflammatory assay using albumin inhibition, F3 achieved the highest inhibition rate, followed by the HMLE extract. In contrast, the extract group exhibited no activity in the antidiabetic test, while the AgNPs group showed the highest antidiabetic activity in F3. Additionally, F3 demonstrated the most potent anticancer activity against breast cancer cells, resulting in the lowest cell viability. Overall, this study suggests that AgNPs synthesized using ML extract enhanced via HME processing exhibit superior physiological activities compared to those synthesized using unprocessed ML extract.</div></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"6 ","pages":"Article 100184"},"PeriodicalIF":4.6,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142527913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silkworm pupae protein-based film incorporated with Catharanthus roseus leaf extract-based nanoparticles enhanced the lipid stability and microbial quality of cheddar cheese","authors":"Sabahu Noor ,&nbsp;Sunil Kumar ,&nbsp;Hina F. Bhat ,&nbsp;Abdo Hassoun ,&nbsp;Rana Muhammad Aadil ,&nbsp;S.A. Khandi ,&nbsp;Mandeep S. Azad ,&nbsp;Gholamreza Abdi ,&nbsp;Zuhaib F. Bhat","doi":"10.1016/j.fhfh.2024.100183","DOIUrl":"10.1016/j.fhfh.2024.100183","url":null,"abstract":"<div><p>The study aimed to develop a silkworm pupae protein-based film for enhancing the lipid oxidative and microbial stability of cheddar cheese. The bioactive properties were imparted to the silkworm pupae protein-based film using an optimum level (2.0%) of <em>Catharanthus roseus</em> leaf extract-based nanoparticles (Cat-Ros-NPs) synthesised following a green method. The cheese samples were packaged within the treated film (T₂, containing 2.0% Cat-Ros-NPs) and compared with control samples [control (cheese samples without any film), T₀ (cheese samples within the films without any bioactive agent) and T₁ {cheese samples within the films containing 2.0% <em>C. roseus</em> leaf extract (Cat-Ros-Ext)}] during 90 days trial (4±1 °C). The addition of bioactive agents (Cat-Ros-Ext or Cat-Ros-NPs) increased the thickness (µm) as well as density (g/ml) of the film, thereby decreasing the transmittance (%), solubility (%), moisture content (%), and water-vapour transmission rate (mg/mt²). Both the bioactive agents increased the redness (a*) and yellowness (b*) whereas decreased the brightness (L*) of the film. The films enhanced the antioxidant and antimicrobial properties of the enclosed cheese samples during storage and the highest values were recorded for the samples packed within T₂ films. The cheese samples packaged within T₂ and T₁ films showed significantly lower values for lipid oxidation and microbial counts. This positive effect of the films (T₂ and T₁) was also recorded on protein oxidation (total-carbonyl content) after day 30 and sensory quality after day 60. Our results indicate the successful use of silkworm pupae protein for the development of bioactive packaging for cheddar cheese.</p></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"6 ","pages":"Article 100183"},"PeriodicalIF":4.6,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667025924000086/pdfft?md5=4d4c151ae03d4ae3f48cbafa7c9597b9&pid=1-s2.0-S2667025924000086-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141984889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}