{"title":"Investigation of functional, antioxidant, anti-inflammatory, and antidiabetic properties of legume seed protein hydrolysates","authors":"Taiwo Scholes Adewole , Michael Chukwuemeka Bieni , Gbenga Emmanuel Ogundepo , Oludele Olayemi Odekanyin , Adenike Kuku","doi":"10.1016/j.fhfh.2023.100175","DOIUrl":"https://doi.org/10.1016/j.fhfh.2023.100175","url":null,"abstract":"<div><p>Plant-derived hydrolysates are emerging as promising agents in the management of diverse ailments due to their ensuing functional and bioactive properties. This study investigated the functional, antioxidant, anti-inflammatory, and antidiabetic properties of hydrolysates from <em>Erythrina senegalensis</em> and <em>Vigna subtenarrea</em> seeds. Crude proteins were isolated via alkaline solubilization, followed by acid precipitation to the isoelectric point. Respective protein isolates were hydrolyzed using trypsin and pepsin at an enzyme-substrate ratio of 1:8 (v/v) for 1–9 h. Pepsin hydrolysates after 9 h elicited the highest solubilities of 95.54 % and 94.24 % at pH 13, while, pepsin and trypsin hydrolysates of <em>E. senegalensis</em> digested for 1 and 9 h displayed the highest 1,1-diphenyl-2-picrylhydrazyl radical-scavenging (10-IC<sub>50</sub> = 2.959 mg/mL) and total antioxidant capacity (7.243 mgAAE/g), respectively. Correspondingly, pepsin and trypsin hydrolysates of <em>E. senegalensis</em> hydrolyzed for 5 h demonstrated the most potent anti-inflammatory activities by cogently inhibiting xanthine oxidase and lipoxygenase activities with IC<sub>50</sub> of 0.161 ± 0.111 and 0.018 ± 0.011 mg/mL, respectively. Trypsin hydrolysates of <em>V. subterranea</em> hydrolyzed for 5 h potently inhibited the activities of α-amylase and α-glucosidase with respective IC<sub>50</sub> of 0.297 ± 0.060 and 0.314 ± 0.064 mg/mL. Overall, pepsin and trypsin hydrolysates of <em>E. senegalensis</em> demonstrated pronounced functional bioactivities relative to <em>V. subterranea</em> hydrolysates. This study concludes that both seeds could serve as unique matrices of potential functional bioactive peptides with prospects for managing diabetes.</p></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667025923000596/pdfft?md5=4599b71b75c5943837cf998af17bab62&pid=1-s2.0-S2667025923000596-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139108068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to “Peptidomic analysis of milk fermented by Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus” [Food Hydrocolloids for Health, 2021, 1, 100033]","authors":"Yang Yu, Wenhao Yu, Yan Jin","doi":"10.1016/j.fhfh.2023.100166","DOIUrl":"10.1016/j.fhfh.2023.100166","url":null,"abstract":"","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266702592300050X/pdfft?md5=9d539eff386e7c4fc08fae06cab8ce05&pid=1-s2.0-S266702592300050X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136160953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in hydrocolloids for food applications: Natural sources, bioactivity and delivery systems","authors":"Marco Garcia-Vaquero","doi":"10.1016/j.fhfh.2023.100172","DOIUrl":"https://doi.org/10.1016/j.fhfh.2023.100172","url":null,"abstract":"","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667025923000560/pdfft?md5=b6db905898174e9ebbd5ffbe47c8d2b4&pid=1-s2.0-S2667025923000560-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138577795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bigels for controlled gastric release of ascorbic acid: Impact on rheology, texture, thermal stability and antioxidant activity","authors":"Admajith M. Kaimal , Rekha S. Singhal","doi":"10.1016/j.fhfh.2023.100171","DOIUrl":"https://doi.org/10.1016/j.fhfh.2023.100171","url":null,"abstract":"<div><p>Ascorbic acid (AA) is a vital nutrient to maintain critical physiological functions but is very sensitive to processing and storage. This can be overcome by using gel-based systems for controlled release of AA. This study compares various gel-based formulations such as hydrogel, emulsion gel, bigel (25 %, 50 %, and 75 % oleogel), and emulsions for thermal stability and delivery of AA, rheological and textural profile, encapsulation efficiency (>97 %), <em>in vitro</em> gastrointestinal release profile, and the corresponding antioxidant profile. An increase in the oleogel content increased the hardness (125 – 216 g) and viscoelastic properties (G′ and G′′) but decreased (76.16 – 25.86 %) the swelling ratio of the bigel. A spontaneous release of AA was witnessed during gastric digestion from emulsion gels (95 %), hydrogels (98 %) and emulsions, whereas a gradual and controlled gastric release of AA could be achieved by bigels. However, a sudden decrease in AA (70 – 80 % reduction) and a spike in dehydroascorbic acid (DHA, oxidized AA) could be observed during intestinal digestion. The bioaccessibility was highest for emulsion gel and bigel (87 %) and lowest for emulsions (70 %). Bigels with higher oleogel content also showed better thermal stability but their physical stability was compromised at higher temperature. The DPPH and ABTS activity was proportional to AA, while FRAP was impacted by both DHA and AA. Thus bigels could be utilised for controlled gastric release of AA with better thermal stability.</p></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667025923000559/pdfft?md5=059004a9167edc30dbf0c33245b5add7&pid=1-s2.0-S2667025923000559-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138474313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shuyang Liu , Hamad Rafique , Liang Zou , Xinzhong Hu
{"title":"Therapeutic effects and mechanism of oat β-glucan plus montmorillonite powder on diarrhea in young rats","authors":"Shuyang Liu , Hamad Rafique , Liang Zou , Xinzhong Hu","doi":"10.1016/j.fhfh.2023.100169","DOIUrl":"10.1016/j.fhfh.2023.100169","url":null,"abstract":"<div><p>Oat β-glucan is a prebiotic that affects intestinal microbiota and maintains energy homeostasis. Oat β-glucan helps treat diarrhea and other associated disorders, because it can regulate intestinal microbiota. We investigated the therapeutic effects and mechanism of oat β-glucan combined with montmorillonite powder on diarrhea induced by Senna leaf extract in young Sprague-Dawley rats. Compared with the diarrhea-induced model group (DM), the combined treatment, especially in the group treated with a medium dose of Montmorillonite powder plus oat β-glucan (M+G2), effectively reduced the diarrhea (<em>P</em> < 0.05) and inflammation indices, alleviated damage to the colon, and promoted weight gain in rats. In the combined treatment group, the relative abundance of Firmicutes increased at the phylum level, while the relative abundance of Proteobacteria and Actinobacteria decreased. At the genus level, the <em>Lactobacillus</em> content recovered, and the proportion of conditional pathogens, such as <em>Prevotella</em> and <em>Paraprevotella</em> decreased. M+G2 treatment significantly reduced diarrhea in young rats, restored intestinal microbiota diversity, and promoted the production of short-chain fatty acids (SCFAs). Based on metabolomics, the mechanism of the anti-diarrheal effect of M+G2 treatment may be related to the regulation of glucose and amino acid metabolism. The metabolic micro-environment was improved through the pentose phosphate and vitamin B6 pathways. The core metabolic regulator in metabolic network analysis was L-aspartic acid. Overall, our findings suggest that the combined treatment of oat β-glucan and montmorillonite powder may provide an effective therapeutic strategy for treating diarrhea and associated disorders by regulating the inflammatory biomarkers, SCFAs, and intestinal microbiota.</p></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667025923000535/pdfft?md5=657660c9350726ed03120d3d7722dccd&pid=1-s2.0-S2667025923000535-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135565138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring bioactive aloe-vera and sterculia gum to develop hydrogel wound dressings by graft-copolymerization","authors":"Baljit Singh, Jasvir Singh, Vikrant Sharma, Ankita Kumari, Diwanshi Sharma","doi":"10.1016/j.fhfh.2023.100168","DOIUrl":"https://doi.org/10.1016/j.fhfh.2023.100168","url":null,"abstract":"<div><p>Keeping in view the progressive future prospectus of carbohydrate research, herein, the potential of bioactive polysaccharides aloe vera (AV) and sterculia gum (SG) was explored to develop network hydrogel wound dressings. Both polysaccharides, acemannan of AV gel and glucuronic-galacturonic acid of SG accelerate wound healing process. The antibiotic drug cefuroxime encapsulated dressings were designed by graft-copolymerization with carbopol. The copolymers were characterized by SEM, AFM, FTIR, C<sup>13</sup> NMR, XRD, TGA-DTG, DSC and swelling studies. The slow diffusion of cefuroxime drug exhibited non-Fickian mechanism and release of drug was occurred with a first order kinetic model. Polymer-bio membrane interactions indicated mucoadhesion nature. The clot formation was reduced during polymer-blood interactions indicated bio-compatible nature of the dressings moreover dressings were found antioxidant in nature. The porous dressings were O<sub>2</sub> permeable and microbial impermeable. The hydrogel dressings revealed antimicrobial activity against <em>P. aeruginosa.</em> Degree of antimicrobial activity enhanced in case of hydrogel wound dressings loaded with cefuroxime. Overall, the results of these biochemical assays, sustained release of antibiotic drug and inherent wound healing potential of AV-SG indicated the use of hydrogels as dressing materials for better wound healing.</p></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667025923000523/pdfft?md5=6a2b0b0190b2a1123a39863f448ca250&pid=1-s2.0-S2667025923000523-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91986750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ha Yeon Lee , Suji Ryu , Han Sol You , Yoo Na Jeon , Minki Jin , Cheong-Weon Cho , Jong-Suep Baek
{"title":"Enhanced antioxidant and anti-inflammatory effects of bee pollen and honey hybrid formulation by hot-melt extrusion","authors":"Ha Yeon Lee , Suji Ryu , Han Sol You , Yoo Na Jeon , Minki Jin , Cheong-Weon Cho , Jong-Suep Baek","doi":"10.1016/j.fhfh.2023.100167","DOIUrl":"https://doi.org/10.1016/j.fhfh.2023.100167","url":null,"abstract":"<div><p>Modifying the complex wall structure of bee pollen is a way to enhance the uptake of bioactive compounds. Bee Pollen and Bee Honey hybrid formulation (BPHF) are made by hot melt extrusion (HME), which is known to be the best cell wall structure-breaking method for active compound extraction because it can break the fibrous matrix of the compounds. Honey and bee pollen mixtures showed increased antioxidant activity with increased phenolic and flavonoid contents and decreased inhibitory concentration 50 (IC<sub>50</sub>) values compared to the control group. In addition, the content of gallic acid, one of the phenolic acids, increased about four times in the HME-F3 formulation compared to the control group, indicating that the phenol content was rich, but the HME-F3 formulation decreased in comparison. All samples had nano-sized particles. The Polydispersity index (PDI) value of the HME-F3 formulation was reduced and well distributed, and the stability of the particles was confirmed in the zeta potential results. Scanning electron microscopy (SEM) showed the image change of the sample after HME compared to the existing bee pollen image, and Transmission electron microscopy (TEM) showed that the particles of the mixed formulation were uniformly dispersed. Fourier-transform Infrared Analysis (FT-IR) results showed that there were structural changes in the mixture formulation compared to the control, and X-ray Diffraction Analysis (XRD) results showed that all samples were amorphous. It was found that the HME-F3 formulation could resist inflammation and protect the function of the intestinal epithelial wall. The mRNA levels of TJ-related proteins in the mixed formulation were reduced compared to LPS treatment and control.</p></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667025923000511/pdfft?md5=d4c09320635394db841585b6afd6d7fd&pid=1-s2.0-S2667025923000511-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92043074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Tarique , Abdelmoneim H. Ali , Jaleel Kizhakkayil , Ren-You Gan , Shao-Quan Liu , Afaf Kamal-Eldin , Mutamed Ayyash
{"title":"Investigating the biological activities and prebiotic potential of exopolysaccharides Produced by Lactobacillus delbrueckii and Lacticaseibacillus rhamnosus: Implications for gut microbiota modulation and rheological properties in fermented milk","authors":"Mohammad Tarique , Abdelmoneim H. Ali , Jaleel Kizhakkayil , Ren-You Gan , Shao-Quan Liu , Afaf Kamal-Eldin , Mutamed Ayyash","doi":"10.1016/j.fhfh.2023.100162","DOIUrl":"https://doi.org/10.1016/j.fhfh.2023.100162","url":null,"abstract":"<div><p>The objective of this research was to explore the functional qualities of two EPSs produced by recently discovered LAB (<em>Lactobacillus delbrueckii</em> (EPS-LB3) and <em>Lacticaseibacillus rhamnosus</em> (EPS-MLB3)) that have potential probiotic benefits. The study involved evaluating their biological characteristics, such as their antioxidant, antidiabetic, antimicrobial, antibiofilm, and antiproliferative activities at various concentrations, as well as investigating their effects on the gut microbiome through <em>in vitro</em> fecal fermentation. Moreover, the study analyzed the rheological properties of the EPSs in fermented bovine milk. The average molecular weights of the extracted EPS were 3762.43 kDa and 1272.19 kDa with monosaccharide compositions of Glu:Rib:Man:Xyl (1.0:16.4:6.6:6.5) and Rib:Man:Xyl:GA:Ara (7.1:1.6:4.8:1.0:9.0) for EPS-LB3 and EPS-MLB3, respectively. EPS-LB3 and EPS-MLB3 at 250 mg/L showed scavenging rates of 34.0 ± 1.7 % and 37.5 ± 1.1 % for DPPH, 47.3 ± 0.8 % and 56.6 ± 0.7 % for ABTS, 38.3 ± 0.5 % and 43.5 ± 0.6 % for SD, 53.9 ± 0.1 % and 54.7 ± 0.1 % for SAS, 10.6 ± 0.1 % and 10.7 ± 0.2 % for HP, 88.8 ± 0.1 % and 84.8 ± 0.5 % for HRS, 80.0 ± 1.4 % and 84.5 ± 0.8 % for MC, as well as 60.6 ± 1.7 % and 58.1 ± 0.9 % for Lipid Oxidation, respectively, suggesting good antioxidant properties. They also exhibited antimicrobial and anti-biofilm effects against several foodborne pathogens, and antiproliferative activities against cancer cell lines. Additionally, the utilization of EPS by several probiotics indicated the prebiotic nature of EPS. The effect of both EPS on gut microbiome by fecal fermentation revealed that these EPS promoted selective bacteria like <em>Faecalibacterium prausnitzii</em> and <em>Ruminococcus bromii</em> in the gut, which are responsible for carbohydrate metabolism and short-chain fatty acid production.</p></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49736424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gopika Puthussery Narayanan, Preetha Radhakrishnan, Pooja Baiju, Asmath Mubeena S
{"title":"Fabrication Of Butterfly Pea Flower Anthocyanin-Incorporated Colorimetric Indicator Film Based On Gelatin/Pectin For Monitoring Fish Freshness","authors":"Gopika Puthussery Narayanan, Preetha Radhakrishnan, Pooja Baiju, Asmath Mubeena S","doi":"10.1016/j.fhfh.2023.100159","DOIUrl":"https://doi.org/10.1016/j.fhfh.2023.100159","url":null,"abstract":"<div><p>Novel visual intelligent pH-indicator film was prepared from the eggshell membrane- gelatin, pectin, and anthocyanin pigment from butterfly pea flower (BP) (<em>Clitoria ternatea</em>). It was used as a real-time pH indicator for predicting food freshness. Eggshells are useful biowaste, gelatin has been extracted from the eggshell membrane and was used for fabricating the film. The Anthocyanin content of BP extract was 198.3 mg g<sup>−1</sup>. The film's surface morphology and chemical nature were estimated using a Scanning electron microscope, Fourier transform infrared spectroscopy, and X-ray diffraction technique. The film was pH responsive and exhibited color variation ranging from shades of red, purple, blue, green, and yellow at different pH (1-13). The applicability of the developed pH- indicator film was studied on fresh Tilapia fish by monitoring its deterioration for a specific time period. The film showed a visible color change after seven days of storage at 4ºC from dark blue, bluish-grey to olive, and deep green. Change in the total volatile basic nitrogen (TVB-N) content and pH change had an effect on the color response of the film. The findings demonstrated that the fabricated pH indicator film proved to be pH sensitive and could be used to monitor fish freshness.</p></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667025923000432/pdfft?md5=9dc1cae27abe2dfb6aa8e5dc95a7e4e7&pid=1-s2.0-S2667025923000432-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91986749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}