FEMS microbiology ecology最新文献_第9页

Successive cultivation under drought selects for specific microbiome members in the wheat rhizosphere. 干旱条件下的连续栽培对小麦根际特定微生物群成员的选择。

IF 4.1 3区生物学

FEMS microbiology ecology Pub Date : 2026-04-16 DOI: 10.1093/femsec/fiag037

Adele Pioppi, Sofia I F Gomes, Mette Nicolaisen, Xinming Xu, Ákos T Kovács

{"title":"Successive cultivation under drought selects for specific microbiome members in the wheat rhizosphere.","authors":"Adele Pioppi, Sofia I F Gomes, Mette Nicolaisen, Xinming Xu, Ákos T Kovács","doi":"10.1093/femsec/fiag037","DOIUrl":"10.1093/femsec/fiag037","url":null,"abstract":"Growing knowledge on plant microbiomes demonstrates the contribution of the host plant during microbiome assembly, especially under stress conditions commonly threatening crops. To dissect the influence of a plant on its microbiome, repeated cycling of microbiomes can be utilized to enhance functional properties in the enriched microbial communities. We used such a successive cultivation approach for wheat (Triticum aestivum) microbiome under drought conditions and selected lineages for drought resilience and susceptibility, with and without enriching the starting community with a library of bacterial isolates obtained from wheat. Significant differences in the rhizosphere microbiome between selection regimes were confirmed through 16S rRNA gene amplicon sequencing. Notably, replicate lineages of each selection regime showed convergence to similar microbiomes. Specific genera were abundant depending on the selection regimes; Stenotrophomonas under drought resilience, while Rahnella under drought conditions when the strain library was added initially. Applying Stenotrophomonas or Rahnella as single inoculum did not improve drought resilience in wheat. We hypothesize that complex microbiome dynamics take place during successive cultivation, which underscores the importance of considering complex plant-microbiome systems for studying plant stress resilience. Successive cultivation remains a valuable approach for observing rhizosphere microbiome changes under different conditions.","PeriodicalId":12312,"journal":{"name":"FEMS microbiology ecology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13114863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Priority effects drive fungal and nematode emergence from insect larvae. 优先效应驱动真菌和线虫从昆虫幼虫中涌现。

IF 4.1 3区生物学

FEMS microbiology ecology Pub Date : 2026-04-16 DOI: 10.1093/femsec/fiag036

Amaury Payelleville, Magdalena Warren, Chloe Golde, Devyn Sasai, Benny Pan, Patrick Cleary, Arizbel Gomez, Rubina Shrestha, Jean-Claude Ogier, Sophie Gaudriault, Christine Jacobs-Wagner, Tadashi Fukami

{"title":"Priority effects drive fungal and nematode emergence from insect larvae.","authors":"Amaury Payelleville, Magdalena Warren, Chloe Golde, Devyn Sasai, Benny Pan, Patrick Cleary, Arizbel Gomez, Rubina Shrestha, Jean-Claude Ogier, Sophie Gaudriault, Christine Jacobs-Wagner, Tadashi Fukami","doi":"10.1093/femsec/fiag036","DOIUrl":"10.1093/femsec/fiag036","url":null,"abstract":"Priority effects, in which species arrival history influences community assembly, are increasingly recognized to affect host-parasite systems. However, priority effects across disparate groups of parasitic organisms are poorly understood despite the wide range of taxonomic groups involved. In California oak woodland, we investigated how priority effects between two insect-parasitic fungi (Metarhizium and Beauveria) influenced emergence of nematodes from insect larvae. Field and laboratory results indicated that both fungi were common, but priority effects prevented them from co-emerging from the same larva. Metarhizium- and Beauveria-infected insects did not differ in the species composition of emerging nematodes, but larvae without fungal emergence had distinct nematode communities, with Oscheius almost always emerging without fungi. Experiments indicated that none of the commonly found nematodes (Acrobeloides, Mesorhabditis, Oscheius, and Rhabditis) were entomopathogenic, but that Oscheius could exclude Beauveria if it arrived early. This time-dependent exclusion was likely caused by a bacterium that Oscheius nematodes carried (Serratia proteamaculans). Together, these findings suggest that fungi enter insects as primary arrivers, while nematodes come as secondary arrivers to exploit fungus-killed insects, with priority effects influencing both groups. We suggest that this system is a promising natural microcosm for understanding priority effects across disparate groups in host-parasite systems.","PeriodicalId":12312,"journal":{"name":"FEMS microbiology ecology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147644727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protein folds and catalytic strategies at the origin of biological CO2 fixation. 生物二氧化碳固定起源的蛋白质折叠和催化策略。

IF 4.1 3区生物学

FEMS microbiology ecology Pub Date : 2026-04-16 DOI: 10.1093/femsec/fiag041

Natalia Mrnjavac

{"title":"Protein folds and catalytic strategies at the origin of biological CO2 fixation.","authors":"Natalia Mrnjavac","doi":"10.1093/femsec/fiag041","DOIUrl":"10.1093/femsec/fiag041","url":null,"abstract":"Biological carbon fixation is the basis of all ecosystems. Out of the seven known pathways organisms use to fix CO2, the acetyl-CoA pathway is assumed to be the most ancient. Its enzymes bear primordial traits, including carbon-metal bonds and an abundance of transition metal clusters. Ancient traits can also be reflected in structural folds adopted by the enzymes and the catalytic strategies they employ. Here I show that the most common catalytic strategies used to accelerate reactions in the acetyl-CoA pathway are cofactor-aided catalysis, electrostatic interactions and general acid/base catalysis. Enzymes of the acetyl-CoA pathway are replete with Rossman folds, TIM barrel folds, and alpha-beta plaits. These topologies evolved before the divergence of bacteria and archaea, along with five other catalytic folds of the acetyl-CoA pathway. Rossmann folds and TIM barrels likely underwent rapid diversification early in the history of life. In contrast, over half of the folds in the pathway are weakly diversified folds that emerged only once in the history of life, at the origin of biological CO2 fixation. Ancient metabolic pathways point to enzymes with conserved structural cores, which uncover topologies and catalytic strategies employed at the onset of metabolism.","PeriodicalId":12312,"journal":{"name":"FEMS microbiology ecology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13156950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147766882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zn-mobilizing bacteria improve shoot biomass and zinc content in wheat. 锌调动菌提高小麦茎部生物量和锌含量。

IF 4.1 3区生物学

FEMS microbiology ecology Pub Date : 2026-04-16 DOI: 10.1093/femsec/fiag030

Belay Berza, Fassil Assefa, Tesfaye Wubet, Undine Behrendt, Sizhong Yang, Paul Reim, Steffen Kolb

{"title":"Zn-mobilizing bacteria improve shoot biomass and zinc content in wheat.","authors":"Belay Berza, Fassil Assefa, Tesfaye Wubet, Undine Behrendt, Sizhong Yang, Paul Reim, Steffen Kolb","doi":"10.1093/femsec/fiag030","DOIUrl":"10.1093/femsec/fiag030","url":null,"abstract":"Enhancing zinc (Zn) content in wheat grains by using Zn-mobilizing rhizosphere bacteria is becoming an eco-friendly and sustainable alternative to conventional approaches such as chemical fertilization. Our study aimed to isolate, screen, and evaluate Zn-mobilizing rhizosphere bacteria to improve its content in wheat biomass. Wheat rhizosphere soils were collected in several wheat planted soils in Ethiopia and Zn-solubilizing bacteria were isolated and screened for their plant beneficial traits. Isolates W8_A, W25_A, and W63_B were selected. Pot experiments were conducted in sterilized river sand supplemented with 0.05% zinc oxide by using these isolates. The experiment consisted of nine treatments in complete randomized design with four replications. Data were means of three independent experiments. W8_A, W25_A, and W63_B exhibited zinc solubilization index > 4.0. Consortium inoculation showed the highest improvements in plant growth. Inoculations improved shoot length and dry weigh on average by 67.4% and 84.2%, respectively compared to the control. On average, 90.2% root and 75.5% shoot Zn content increased compared to the untreated control. Hence, the isolates can be applied for Zn bio-fortification in wheat to combat Zn deficiencies in food grains.","PeriodicalId":12312,"journal":{"name":"FEMS microbiology ecology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ecological assessment of physico-chemical factors influencing the diversity and abundance of cyanobacteria in lakes of Côte d'Ivoire (Kan, Koubi, Loka, and Tiebissou). 影响Côte科特迪瓦（Kan、Koubi、Loka和Tiebissou）湖泊蓝藻多样性和丰度的理化因素生态评价

IF 4.1 3区生物学

FEMS microbiology ecology Pub Date : 2026-04-16 DOI: 10.1093/femsec/fiag035

Soumahoro Fatoumata Grace, Aw Sadat, Yao Djeha Rosine, Ouattara Bamory, Kouadio Meliton Djezou, Coulibaly Kalpy Julien

{"title":"Ecological assessment of physico-chemical factors influencing the diversity and abundance of cyanobacteria in lakes of Côte d'Ivoire (Kan, Koubi, Loka, and Tiebissou).","authors":"Soumahoro Fatoumata Grace, Aw Sadat, Yao Djeha Rosine, Ouattara Bamory, Kouadio Meliton Djezou, Coulibaly Kalpy Julien","doi":"10.1093/femsec/fiag035","DOIUrl":"10.1093/femsec/fiag035","url":null,"abstract":"Cyanobacteria are photosynthetic microorganisms found in all aquatic ecosystems. Some species produce toxins, posing risks to human and animal health. In Côte d'Ivoire, information on the composition and dynamics of freshwater cyanobacterial communities remains limited. This study aims to assess the influence of physico-chemical parameters on alpha diversity, cyanobacterial abundance, and phytoplankton biomass, while comparing community responses to anthropogenic pressures (urban, agricultural, and aquaculture). Nine sampling campaigns conducted between March 2023 and May 2024 included in situ measurements (pH, temperature, and turbidity) and laboratory analyses of nutrients and chlorophyll-a. Cyanobacteria were identified microscopically and quantified using a Malassez chamber. A total of 19 genera were recorded. Highly impacted lakes were dominated by opportunistic taxa (Aphanocapsa, Pseudanabaena, and Microcystis), whereas the reference lake was characterized by genera with high ecological plasticity (Cylindrospermopsis and Anabaena). Cyanobacterial abundance was positively correlated with pH and temperature, chlorophyll-a with pH and turbidity, and alpha diversity declined with increasing turbidity. Multivariate analyses (GLM, RDA, and NMDS) confirmed a significant influence of environmental variables on community structure. These findings indicate that cyanobacterial dynamics are primarily driven by physicochemical conditions and the intensity of anthropogenic pressures, highlighting the need for targeted ecological monitoring to support sustainable freshwater management.","PeriodicalId":12312,"journal":{"name":"FEMS microbiology ecology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13098367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147580282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review on soil microbial shifts under drought stress: a climate-smart agriculture perspective. 干旱胁迫下土壤微生物变化的系统综述：气候智能型农业的视角。

IF 4.1 3区生物学

FEMS microbiology ecology Pub Date : 2026-04-16 DOI: 10.1093/femsec/fiag044

Ndivhuwo Ramatsitsi, Alen Manyevere

{"title":"A systematic review on soil microbial shifts under drought stress: a climate-smart agriculture perspective.","authors":"Ndivhuwo Ramatsitsi, Alen Manyevere","doi":"10.1093/femsec/fiag044","DOIUrl":"10.1093/femsec/fiag044","url":null,"abstract":"Major shifts in temperature and rainfall patterns resulting from climate change are projected to continue increasing intensely over the course of the century. Ecosystems' functionality and well-being of above-ground plant community are all significantly impacted by soil microbes' response to these shifting abiotic stresses. With an emphasis on improving their usefulness in climate-smart agriculture (CSA), we reviewed how soil bacteria and fungi tolerate drought stress and improve plant development under water shortage conditions. This systematic analysis used Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) to elaborate how microbe-based solutions could be incorporated in CSA. A total of 31 articles satisfied the inclusion criteria. The review demonstrated that soil microbial diversity and abundance are considerably altered by drought stress, improve resilience of plants, and soil functionality. There was a further observation of high microbial community in the endosphere, and rhizosphere as compared to bulk soil; a clear indication of plants' potential to facilitate soil microbial assemblages. Evidently, plants under drought conditions exude metabolites that stimulate drought-tolerant microbes; that in-turn promote the plants' tolerance to drought. Accordingly, this remarkable synergy between microbes and plants could help forecast how agroecosystems would function in the face of climate change.","PeriodicalId":12312,"journal":{"name":"FEMS microbiology ecology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13170800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147766902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salinity and vegetation shape methylotrophic methanogen diversity and potential activity in coastal sediments. 盐度和植被对沿海沉积物甲基营养型甲烷菌多样性和潜在活性的影响。

IF 4.1 3区生物学

FEMS microbiology ecology Pub Date : 2026-04-16 DOI: 10.1093/femsec/fiag043

Alejandro Huerta-Hurtado, Stephania L Tsola, Mark Trimmer, Özge Eyice

{"title":"Salinity and vegetation shape methylotrophic methanogen diversity and potential activity in coastal sediments.","authors":"Alejandro Huerta-Hurtado, Stephania L Tsola, Mark Trimmer, Özge Eyice","doi":"10.1093/femsec/fiag043","DOIUrl":"10.1093/femsec/fiag043","url":null,"abstract":"Anoxic coastal sediments are significant natural sources of the potent greenhouse gas methane where, methylotrophic methanogenesis may predominate. However, the underlying methanogen community composition as well as the impact of salinity levels and vegetation on their diversity and potential activity remain poorly resolved. To assess methane production and characterize methanogen diversity underlying methanol and trimethylamine (TMA) degradation, we incubated anoxic sediments from three sites along the Medway Estuary (UK)-a high-salinity marine site and two brackish sites, one vegetated (saltmarsh with cordgrass) and one non-vegetated. Saltmarsh sediments exhibited the highest methane yields (46% from TMA, 27% from methanol), whereas we did not observe methanogenesis from methanol in the high-salinity marine samples. Methylotrophic methanogen genera Methanolobus, Methanomethylophilus, and Methanofastidiosum were abundant in all original sediments, where metabolic generalist Methanosarcinales were also present. Methanoculleus were the most abundant taxon (31.5%) in original brackish sediments, while they were only at 1% in saltmarsh sediments. Following the amendment with TMA or methanol, Methanolobus dominated all the sediments with methane production (80%-99.5% relative abundance), however Methanoculleus were still in high relative abundance in brackish incubations with methanol or TMA (4.6% and 10%, respectively). These findings indicate that both salinity and vegetation shape the community composition of methylotrophic methanogens in coastal sediments, yet key methylated substrates are primarily metabolized by Methanolobus, regardless of differences in salinity and vegetation.","PeriodicalId":12312,"journal":{"name":"FEMS microbiology ecology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13137993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147766906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: thematic issue on thermophiles. 社论：关于嗜热菌的专题问题。

IF 4.1 3区生物学

FEMS microbiology ecology Pub Date : 2026-04-16 DOI: 10.1093/femsec/fiag045

Olga V Golyshina, Tillmann Lüders, Peter N Golyshin

引用次数: 0

Resilience and response of marine microbes to the future ocean and a marine heatwave - insights from a mesocosm experiment. 海洋微生物对未来海洋和海洋热浪的恢复力和反应——来自中生态实验的见解。

IF 4.1 3区生物学

FEMS microbiology ecology Pub Date : 2026-04-16 DOI: 10.1093/femsec/fiag042

Jan D Brüwer, Micah Reismann, Antje Wichels, Uwe John, Josefin Schmidt, Cédric L Meunier, Bernhard M Fuchs, Inga V Kirstein

{"title":"Resilience and response of marine microbes to the future ocean and a marine heatwave - insights from a mesocosm experiment.","authors":"Jan D Brüwer, Micah Reismann, Antje Wichels, Uwe John, Josefin Schmidt, Cédric L Meunier, Bernhard M Fuchs, Inga V Kirstein","doi":"10.1093/femsec/fiag042","DOIUrl":"10.1093/femsec/fiag042","url":null,"abstract":"Anthropogenic influences are reshaping ocean conditions, with rising sea surface temperatures, elevated CO2 concentrations, and shifting nutrient dynamics occurring alongside more frequent extreme weather events. While previous studies indicated that various planktonic taxa may be impacted by long-term environmental change, the response of the microbial community remains less explored, and we know particularly little about how short-term events such as marine heatwaves interact with long-term environmental changes. Here, we investigated the impact of a heatwave (+2°C for 5 days) on the microbial community in mesocosms mimicking ambient and future coastal conditions (1000 ppm CO2, +3°C, Nitrogen: Phosphate ratio of 25), according to IPCC predictions (high-emission scenario RCP 8.5) for 2100. We used 16S rRNA gene sequencing, fluorescence microscopy, and experimental approaches, to study the microbial community taxonomic composition, cell abundances, virus-like particle abundances, as well as cell division and mortality rates. Our results indicate that future coastal conditions may impact the microbial community composition, biodiversity, as well as the abundance of total bacterioplankton. In contrast, the marine heatwave we simulated had a smaller impact on the microbial community composition, and we did not observe any effect of the heatwave on virus-like particle counts and cell division rates. In conclusion, our findings suggest a certain resilience of the microbial community to short-term thermal disturbances.","PeriodicalId":12312,"journal":{"name":"FEMS microbiology ecology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13152010/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147766949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypobaric hypoxia affects gut microbiota of rats through affected community assembly, reduced network resilience, and metabolic reprogramming. 低气压缺氧通过影响群落聚集、降低网络弹性和代谢重编程影响大鼠肠道微生物群。

IF 4.1 3区生物学

FEMS microbiology ecology Pub Date : 2026-04-16 DOI: 10.1093/femsec/fiag039

Xinyang Chen, Yihong Wang, Jianzhuo Feng, Huiqing Chen, Baohui Yao, Fuxin Li, Quanyu Yang, Jiapeng Qu

{"title":"Hypobaric hypoxia affects gut microbiota of rats through affected community assembly, reduced network resilience, and metabolic reprogramming.","authors":"Xinyang Chen, Yihong Wang, Jianzhuo Feng, Huiqing Chen, Baohui Yao, Fuxin Li, Quanyu Yang, Jiapeng Qu","doi":"10.1093/femsec/fiag039","DOIUrl":"10.1093/femsec/fiag039","url":null,"abstract":"In host-microbe interactions, host diet and environmental stress are key driving factors shaping the gut microbiota. Although previous studies have shown that hypoxia affects the structure and function of the gut microbiota in rodents, most have relied on 16S rRNA gene sequencing and lacked analysis of community assembly mechanisms, co-occurrence networks, and functional pathways. Here, we used metagenomic next-generation sequencing (mNGS) to examine the gut microbiota of rats exposed to hypobaric hypoxia (WH, simulated 6000 m altitude) compared to WL group (2100 m altitude). Hypoxia significantly altered β-diversity of gut microbiota, but did not affect its α-diversity. Community assembly was primarily governed by stochastic processes, with hypoxia stress reducing their impact. Microbial co-occurrence networks were dominated by positive correlations, although network resilience and stability declined under hypoxia. Helicobacter and Eubacterium were identified as high-abundance differentiating genera, and Akkermansia muciniphila was significantly enriched in WH group. Functional analysis revealed alterations in pathways related to protein synthesis and carbohydrate metabolism, suggesting that hypoxia may affect nutrient utilization by the host. Overall, these findings provide a comprehensive view of how hypoxic stress reshapes the gut microbiota of rats, offering new insights into microbial dynamics under environmental stress.","PeriodicalId":12312,"journal":{"name":"FEMS microbiology ecology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13131234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147698030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0