Fertility and sterility最新文献

{"title":"Isthmocele-fix it or observe, an ongoing dilemma.","authors":"Anuja Dokras, Edgardo Somigliana, Olivier Donnez, Leigh A Humphries, Divya K Shah, Mindy S Christianson, Dominique de Ziegler","doi":"10.1016/j.fertnstert.2025.03.007","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2025.03.007","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracytoplasmic sperm injection is the only treatment for male factor—or NOT?","authors":"Peter N. Schlegel M.D.","doi":"10.1016/j.fertnstert.2025.02.011","DOIUrl":"10.1016/j.fertnstert.2025.02.011","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 4","pages":"Page 573"},"PeriodicalIF":6.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A commentary on “Association between sleep quality and ovarian reserve in women of reproductive age: a cross-sectional study”","authors":"Mo-Yao Tan M.D., Ping Zhang M.D., Ming Gao M.D.","doi":"10.1016/j.fertnstert.2024.10.027","DOIUrl":"10.1016/j.fertnstert.2024.10.027","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 4","pages":"Page 736"},"PeriodicalIF":6.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chromosomal abnormalities in oocyte donor candidates: a French survey of over 8,200 karyotypes","authors":"Vincent Puy M.D., Ph.D. , Badria Bennani Smires M.D. , Jean-Pierre Siffroi M.D., Ph.D. , Julie Barberet Pharm.D., Ph.D. , Marion Bendayan M.D. , Oxana Blagosklonov M.D., Ph.D. , Florence Brugnon M.D., Ph.D. , Rosalie Cabry-Goubet M.D., Ph.D. , Marie-Ange Clarotti M.D. , Sophie Catteau-Jonard M.D., Ph.D. , Céline Chalas Pharm.D., Ph.D. , Lucie Chansel-Debordeaux Pharm.D., Ph.D. , Béatrice Delepine M.D. , Laetitia Hesters Pharm.D. , Stéphanie Lattès M.D. , Floriane Lefeuve M.D. , Arthur Luton Pharm.D. , Catherine Metzler-Guillemain M.D. Ph.D. , Sophie Mirallié Pharm.D. , Joffrey Mons M.D. , Florence Eustache M.D., Ph.D.","doi":"10.1016/j.fertnstert.2024.10.037","DOIUrl":"10.1016/j.fertnstert.2024.10.037","url":null,"abstract":"<div><h3>Objective</h3><div>To study karyotypes of >8,200 oocyte donor candidates in nulliparous or multiparous women compared with a reference population.</div></div><div><h3>Design</h3><div>A retrospective observational multicentric study.</div></div><div><h3>Subjects</h3><div>The study included 2 cohorts of oocyte donor candidates recruited between January 2005 and October 2021: multiparous women with at least 1 child at the time of recruitment and nulliparous women. Both were compared with a reference population composed of female newborns from literature.</div></div><div><h3>Exposure</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>Blood lymphocyte karyotype.</div></div><div><h3>Results</h3><div>A total of 8,229 oocyte donor candidates from 22 fertility centers were included in this study. Nulliparous (n = 1,890) and multiparous (n = 6,339) women were compared with 8,102 female newborns. Overall, 65 candidates were carriers of chromosomal abnormalities and were, therefore, excluded from the donation process (0.79%; 95% confidence interval [CI], 0.60–0.98). The occurrence of balanced structural chromosomal rearrangements globally increased in the study population (0.49%; 95% CI, 0.34–0.64) compared with that in female newborns (0.24%; 95% CI, 0.34–0.64). The number of reciprocal translocations increased fivefold in nulliparous oocyte donor candidates (0.37%; 95% CI, 0.10–0.64). The incidence of sex chromosome mosaicism notably increased in multiparous oocyte donor candidates, with 17 cases (0.27%; 95% CI, 0.14–0.40). Among chromosomal aberration carriers, only 2 nulliparous women (1 reciprocal translocation and 1 sex chromosome mosaicism) had fertility issues with a diagnosis of premature ovarian failure.</div></div><div><h3>Conclusion</h3><div>In this comprehensive 16-year French experience of karyotyping in oocyte donor candidates, we confirmed an increased incidence of balanced structural chromosomal rearrangements, especially among those without children at the time of recruitment. Karyotyping could be considered to identify any chromosomal abnormalities that may not be easily detectable through medical questioning. These abnormalities pose an inherent genetic risk for gamete recipients if left undetected.</div></div><div><div>Anomalías cromosómicas en candidatas a donantes de ovocitos: un estudio francés sobre más de 8,200 cariotipos</div></div><div><h3>Objetivo</h3><div>Estudiar los cariotipos de > 8,200 candidatas a donantes de ovocitos en mujeres nulíparas o multíparas en comparación con una población de referencia.</div></div><div><h3>Diseño</h3><div>Estudio multicéntrico observacional retrospectivo.</div></div><div><h3>Sujetos</h3><div>El estudio incluyó 2 cohortes de candidatas a donantes de ovocitos reclutadas entre enero de 2005 y octubre de 2021: mujeres multíparas con al menos 1 hijo en el momento del reclutamiento y mujeres nulíparas. Ambas se compararon con una población de referencia compuest","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 4","pages":"Pages 692-699"},"PeriodicalIF":6.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142563858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of concern: \"Expression of concern 'Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled study' [Fertility and Sterility 82 (2004) 145-148].","authors":"","doi":"10.1016/j.fertnstert.2025.01.025","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2025.01.025","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 4","pages":"746"},"PeriodicalIF":6.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Will indocyanine green shed light on accessory cavitated uterine malformations?","authors":"Christopher K. Arkfeld M.D. , Alexandra Huttler M.D. , Victoria Fitz M.D., M.S.","doi":"10.1016/j.fertnstert.2025.01.020","DOIUrl":"10.1016/j.fertnstert.2025.01.020","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 4","pages":"Page 606"},"PeriodicalIF":6.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “Higher live birth rates are associated with a normal body mass index in preimplantation genetic testing for aneuploidy frozen embryo transfer cycles: a Society for Assisted Reproductive Technology Clinic Outcome Reporting System study” [Fertil Steril 2024;121:291-98]","authors":"Andrea Peterson M.D., M.S.C.R. , Haotian Wu Ph.D. , Michelle Kappy M.D. , Alexander Kucherov M.D. , Manvinder Singh M.D. , Harry Lieman M.D. , Sangita Jindal Ph.D., H.C.L.D.","doi":"10.1016/j.fertnstert.2024.11.025","DOIUrl":"10.1016/j.fertnstert.2024.11.025","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 4","pages":"Page 742"},"PeriodicalIF":6.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and outcomes in endometrioma infections: a cohort of 94 cases","authors":"Guillaume Parpex M.D., M.Sc. , Martin Belan M.D. , Asmaa Tazi M.D., Ph.D. , Laetitia Campin M.D. , Simon Ganancia M.D. , Etienne Canouï M.D. , Mathilde Bourdon M.D., Ph.D. , Charles Chapron M.D., Ph.D. , Louis Marcellin M.D., Ph.D. , Caroline Charlier M.D., Ph.D.","doi":"10.1016/j.fertnstert.2024.11.002","DOIUrl":"10.1016/j.fertnstert.2024.11.002","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 4","pages":"Pages 724-726"},"PeriodicalIF":6.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142617689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Childhood adversity and doctor visits in gynecology: to screen or not to screen","authors":"Janneke van ’t Hooft M.D., Ph.D. , Dinushi De Alwis M.D. , Ben Willem Mol M.D., Ph.D.","doi":"10.1016/j.fertnstert.2024.12.018","DOIUrl":"10.1016/j.fertnstert.2024.12.018","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 4","pages":"Pages 598-599"},"PeriodicalIF":6.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epigenetic implications of socioeconomic status and education on sperm DNA methylation patterns","authors":"Kelaney Stalker B.S. , Chad Pollard B.S. , Neil J. Perkins Ph.D. , Elizabeth A. DeVilbiss Ph.D. , Tim Jenkins Ph.D.","doi":"10.1016/j.fertnstert.2024.10.010","DOIUrl":"10.1016/j.fertnstert.2024.10.010","url":null,"abstract":"<div><h3>Objective</h3><div>To identify differentially methylated regions and assess epigenetic age and instability scores within each cohort of differing income levels and educational attainment.</div></div><div><h3>Design</h3><div>Retrospective analysis of epigenetic data.</div></div><div><h3>Subjects</h3><div>A total of 1,429 semen samples from participants in the Folic Acid and Zinc Supplementation Trial study.</div></div><div><h3>Exposure</h3><div>Socioeconomic status, approximated by self-reported income, and education level.</div></div><div><h3>Main Outcome Measures</h3><div>Differential sperm DNA methylation, epigenetic age, epigenetic stability.</div></div><div><h3>Results</h3><div>There were four significant differentially methylated regions associated with the income cohorts and seven associated with the education cohorts, suggesting epigenetic patterns vary with socioeconomic status. Adjusted epigenetic age (germ-line age differential values) did not differ significantly in either cohort; however, a higher number of unstable promoters were observed in the lowest education cohort, indicating dysregulation in the epigenome.</div></div><div><h3>Conclusion</h3><div>These findings suggest a biologic link between income and education level in sperm epigenetic patterns, which may influence reproductive health. The increase in unstable promoters in the lower education cohorts may contribute to health disparities associated with educational attainment; however, it is important to consider lifestyle factors and environmental exposures as potential underlying causes. Further research is needed to fully elucidate the implications of these epigenetic changes and their relationship to health outcomes.</div></div><div><h3>Clinical Trial Registration Number</h3><div><span><span>Clinicaltrials.gov</span><svg><path></path></svg></span>, NCT#01857310.</div></div><div><div>Implicaciones epigenéticas del estatus socioeconómico y la educación en los patrones de metilación del ADN espermático</div></div><div><h3>Objetivo</h3><div>Identificar regiones diferencialmente metiladas y evaluar la edad epigenética y los índices de inestabilidad dentro de cada cohorte según los diferentes niveles de ingresos y el grado de escolaridad.</div></div><div><h3>Diseño</h3><div>Análisis retrospectivo de datos epigenéticos.</div></div><div><h3>Sujetos</h3><div>Un total de 1429 muestras de semen de participantes del estudio \"Folic Acid and Zinc Supplementation Trial\"</div></div><div><h3>Exposición</h3><div>Estatus socioeconómico, aproximado mediante el nivel de ingresos autodeclarado y el grado de educación alcanzado.</div></div><div><h3>Principales variables de resultado</h3><div>Metilación diferencial del ADN espermático, edad epigenética y estabilidad epigenética.</div></div><div><h3>Resultados</h3><div>Se identificaron cuatro regiones diferencialmente metiladas asociadas con los distintos niveles de ingresos y siete regiones relacionadas con el grado de escolaridad, lo qu","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 4","pages":"Pages 616-623"},"PeriodicalIF":6.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}