Masato Tamate, Liza Johannesson, Johanna Bayer, Giuliano Testa
{"title":"Standardization of recipient surgery for Uterus Transplantation.","authors":"Masato Tamate, Liza Johannesson, Johanna Bayer, Giuliano Testa","doi":"10.1016/j.fertnstert.2025.02.008","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2025.02.008","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Subtle Challenge of Von Willebrand Disease in Obstetrics, Infertility and Gynecology.","authors":"Pankaj D Desai","doi":"10.1016/j.fertnstert.2025.02.004","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2025.02.004","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Attilio Di Spiezio Sardo, Giuseppe Gabriele Iorio, Serena Guerra, Keith Isaacson, Dimitrios Kafetzis, Alessandro Conforti, Maria Chiara De Angelis, Brunella Zizolfi, Carlo Alviggi
{"title":"The role of hysteroscopy in patients with adenomyosis and infertility: bringing out the submerged.","authors":"Attilio Di Spiezio Sardo, Giuseppe Gabriele Iorio, Serena Guerra, Keith Isaacson, Dimitrios Kafetzis, Alessandro Conforti, Maria Chiara De Angelis, Brunella Zizolfi, Carlo Alviggi","doi":"10.1016/j.fertnstert.2025.02.003","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2025.02.003","url":null,"abstract":"<p><strong>Objective: </strong>To describe how hysteroscopic treatment of adenomyotic cystic lesions of the innermyometrium, persisting after pharmacological treatment, can improve reproductive outcomes in patients with multiple IVF failures.</p><p><strong>Design: </strong>Video case series demonstrating the infertility work-up and the hysteroscopic treatment of adenomyotic cystic lesions of the inner myometrium in infertile patients with multiple IVF failures.</p><p><strong>Setting: </strong>University tertiary care hospital - Fertility Centre.</p><p><strong>Patient(s): </strong>Out of a large experience of patients with infertility and inner myometrium(IM)/junctional zone (JZ) cystic adenomyosis undergoing IVF in the Fertility Centre of our University Hospital, we selected 3 patients for this case series. All three patients had personal history of repeated implantation failure (RIF) and sonographic evidence of adenomyosis (myometrial cysts).</p><p><strong>Exposure: </strong>Patients underwent initial pelvic 2D and 3D sonographic assessment, according to the protocol of the Fertility Centre of our University Hospital. All patients were diagnosed with adenomyosis (myometrial cysts). The patients were treated with GnRH agonists for at least 2 months, to achieve hypoestrogenism (serum estradiol <40 pg/ml) and lesions shrinkage. If hypoestrogenism was not achieved, letrozole was added. In case of lesions persistence at ultrasound (i.e. cysts refractory to pharmacological treatment), patients underwent hysteroscopy and identified lesions were treated under sonographic guidance. One month after hysterosocopy, embryo transfer (ET) was performed.</p><p><strong>Main outcome measure(s): </strong>Achievement of pregnancy in infertile women with multiple IVF failures and adenomyotic cystic lesions, undergoing medical and surgical treatment for adenomyosis.</p><p><strong>Result(s): </strong>Not all cystic adenomyotic lesions of the inner myometrium regress after HPO suppressive treatment (GnRH agonist). When GnRH agonist treatment is not sufficient to achieve satisfactory hypoestrogenism, letrozole is an effective add-on. In cases of refractory lesions at ultrasound, hysteroscopic treatment can improve reproductive outcomes. Patients undergoing combined hysteroscopic and medical treatment achieved pregnancy.</p><p><strong>Conclusion(s): </strong>The optimal management of adenomyotic cystic lesions in patients undergoing IVF is debated. This case series suggests the usefulness of hysteroscopic treatment of adenomyotic cystic lesions persistent after medical therapy, in infertile patients with personal history of multiple IVF failures. We propose a combined medical and surgical treatment strategy. Further studies are required to validate the proposed protocol.</p>","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masato Tamate, Laura Divine, Giuliano Testa, Liza Johannesson
{"title":"Standardization of Robotic-assisted Living Donor Hysterectomy for Uterus Transplantation.","authors":"Masato Tamate, Laura Divine, Giuliano Testa, Liza Johannesson","doi":"10.1016/j.fertnstert.2025.02.006","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2025.02.006","url":null,"abstract":"<p><strong>Objective: </strong>To present a standardized surgical technique of robotic-assisted living donor hysterectomy for Uterus transplantation with preservation of the donor ovaries.</p><p><strong>Design: </strong>Step-by-step description of surgical technique and live-action narrated surgical footage showing uterus donor hysterectomy.</p><p><strong>Setting: </strong>Tertiary-level referral academic center.</p>","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can we please connect the dots on climate and health?","authors":"Micaela Stevenson Wyszewianski, Ruben Alvero","doi":"10.1016/j.fertnstert.2025.02.002","DOIUrl":"https://doi.org/10.1016/j.fertnstert.2025.02.002","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":" ","pages":""},"PeriodicalIF":6.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A commentary on: “Preovulation body mass index and pregnancy after first frozen embryo transfer in patients with polycystic ovary syndrome and insulin resistance”","authors":"Mei Yang , Jiahe Wu , Xinyue Zhang","doi":"10.1016/j.fertnstert.2024.09.040","DOIUrl":"10.1016/j.fertnstert.2024.09.040","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 2","pages":"Page 379"},"PeriodicalIF":6.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply of the authors: from breast cancer to fertility outcomes: increasing understanding of urgent fertility preservation","authors":"Maëliss Peigné M.D., Ph.D. , Michaël Grynberg M.D., Ph.D. , Charlotte Sonigo M.D., Ph.D.","doi":"10.1016/j.fertnstert.2024.10.013","DOIUrl":"10.1016/j.fertnstert.2024.10.013","url":null,"abstract":"","PeriodicalId":12275,"journal":{"name":"Fertility and sterility","volume":"123 2","pages":"Page 376"},"PeriodicalIF":6.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}