{"title":"Review of the domestic market of rectal drugs","authors":"V. Skupchenko","doi":"10.33920/med-13-2301-06","DOIUrl":"https://doi.org/10.33920/med-13-2301-06","url":null,"abstract":"The article deals with modern rectal drugs registered in the Russian Federation. This review presents the structure of the market for rectal dosage forms and their classification; some of the features of specific drugs are also considered.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"22 3-4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82574391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. I. Gavrilov, S. Tishkov, E. V. Blynskaya, K. Alekseev, S. V. Minaev, D.M. Abramova
{"title":"Development of approaches to the creation of self-emulsifying drug delivery systems","authors":"D. I. Gavrilov, S. Tishkov, E. V. Blynskaya, K. Alekseev, S. V. Minaev, D.M. Abramova","doi":"10.33920/med-13-2301-03","DOIUrl":"https://doi.org/10.33920/med-13-2301-03","url":null,"abstract":"This review describes the advantages and disadvantages of a self-emulsifying drug delivery system (SEDDS). A classification of lipid-based formulations is given. An algorithm for the development of the SEDDS composition is proposed.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86588694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination of sugar content in flowers and herbs of scentless chamomile (Tripleurospermum inodorum (L.) Sch. Bip.)","authors":"A. Marakhova, V. Zhilkina, A. A. Elapov","doi":"10.33920/med-13-2210-02","DOIUrl":"https://doi.org/10.33920/med-13-2210-02","url":null,"abstract":"Tripleurospermum inodorum (L.) Sch. Bip. is not used in Russian official medicine, however, this plant is extensively used in folk medicine. Previously, we proved the effect of scentless chamomile extracts on the growth suppression of such microorganisms as Staphylococcus aureus, Escherichia coli, and Candida albicans. It is topical to study the composition of polysaccharides and free sugars, which can have an antimicrobial effect, according to the literature data. The analysis has indicated that scentless chamomile flowers are richer in polysaccharides (2.58±0.04) than the herbs (1.68±0.05); the flowers also contain more sucrose and glucose. In terms of fructose content, herbs and flowers of scentless chamomile practically do not differ.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91412279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Alekseev, E. Blynskaya, V. Bueva, S. Tishkov, V. Alekseev, V. Eremin, A.I. Topilin
{"title":"Review of the current state of research in the field of film creation","authors":"K. Alekseev, E. Blynskaya, V. Bueva, S. Tishkov, V. Alekseev, V. Eremin, A.I. Topilin","doi":"10.33920/med-13-2210-03","DOIUrl":"https://doi.org/10.33920/med-13-2210-03","url":null,"abstract":"A review of Russian and foreign literature on the current state of research in the field of creating ocular, oral, and vaginal films was carried out. The films development prospect for the prevention and treatment of various pathologies is shown.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90154693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of lemon balm (Melissa officinalis L.) on anxiety and depression","authors":"K. O. Shnaider, M. Maksimov, V. Baranova","doi":"10.33920/med-13-2210-01","DOIUrl":"https://doi.org/10.33920/med-13-2210-01","url":null,"abstract":"Depression therapy and prevention is a topical issue of today's medicine. Most drugs used in the treatment of mental disorders have many side effects that affect the quality of life. Herbal medicines have a high level of availability and an almost complete absence of adverse drug effect manifestations. Melissa officinalis is widely used in Oriental medicine for the treatment of mental disorders, which can be considered as an opportunity to use lemon balm as an adjunctive therapy for depression and other mental disorders. The aim of the review is to pool the available data on adjunctive Melissa officinalis therapy for mental disorders. Materials and methods. We identified potentially relevant trials by searching MEDLINE, SCOPUS, PubMed, Google Scholar, and the Cochrane Database of Systematic Reviews from inception to June 2022 using the terms: lemon balm, depression, anxiety, psychiatric disorders, irritation, therapy, efficacy. Further, according to the inclusion and exclusion criteria, as well as by means of independent selection, all the authors of this article selected the sources that met the criteria and compiled this review. Results. Clinical trials show the effectiveness of Melissa officinalis in the treatment of anxiety, depression, and insomnia, however, due to the heterogeneity of the statistical data, the results should be regarded as preliminary until the completion of further studies with more homogeneous groups of participants and standardized dosages, dosage forms, and duration of administration.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81440262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modernization of higher education academic programs at the Faculty of Pharmacy, Sechenov First Moscow State Medical University, in the period from 2013/2014 to 2017/2018 academic years","authors":"N. S. Golikova","doi":"10.33920/med-13-2210-04","DOIUrl":"https://doi.org/10.33920/med-13-2210-04","url":null,"abstract":"In the period of 2015–2018, a comprehensive medical and sociological study of the compliance of the professional training of pharmacists graduating from Moscow higher educational institutions with the requirements of regional pharmaceutical enterprises was carried out. As a result of the questionnaire surveys and a series of expert interviews, critically important skills, abilities, and knowledge necessary for young professionals were identified. The results of the study, analyzed and implemented in the practice of the Sechenov First Moscow State Medical University of the Ministry of Health of Russia as changes in the academic programs of the Faculty of Pharmacy, are presented in this article.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80223506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rational methods of substance abuse treatment","authors":"M. Turgunov, O. Eshonkhuzhaev","doi":"10.33920/med-13-2208-12","DOIUrl":"https://doi.org/10.33920/med-13-2208-12","url":null,"abstract":"The aim of the work was to study modern methods of treatment of substance abuse with various psychoactive substances. Materials and methods. Analysis of literature data on the pharmacotherapy of various forms of substance abuse.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85589592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacotherapy and efficacy of antihypoxants and antioxidants","authors":"D. A. Pasenko","doi":"10.33920/med-13-2208-07","DOIUrl":"https://doi.org/10.33920/med-13-2208-07","url":null,"abstract":"In clinical practice, antihypoxants, «deproteinized calf blood hemoderivatives », and an antioxidant, «ethylmethylhydroxypyridine succinate», are used in the treatment of cerebral ischemic stroke and transient attacks. The use of these drugs is pathophysiologically justified as it prevents neuronal damage, which is confirmed by the clinical guidelines «Ischemic Stroke and Transient Ischemic Attack in Adults», 2021. However, these drugs have not been proven effective. The purpose of the work: to study the expected effect of these drugs, based on pharmacodynamics and pharmacokinetics, as well as biochemical and physiological (pathophysiological) capabilities of the body.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78545337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Charyeva, A. Annameredova, D. Ilamanova, B. Annaev
{"title":"Risk factors in elderly patients with arterial hypertension","authors":"A. Charyeva, A. Annameredova, D. Ilamanova, B. Annaev","doi":"10.33920/med-13-2208-21","DOIUrl":"https://doi.org/10.33920/med-13-2208-21","url":null,"abstract":"Arterial hypertension (AH), being a complex disease, ultimately leads to patient disability and mortality. Currently, due to the relative increase in the number of elderly people, the number of patients with hypertension is also growing. Despite sufficient information about AH, many problems remain poorly studied, including the definition of risk factors, the possibility of determining the predictors of complications, and measures to prevent the disease. The aim of the study was to identify the features of hypertension risk factors in the elderly.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"128 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89220914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. A. Orazklychev, B. G. Khodzhakuliev, M. K. Kurdova, B. M. Ovezklychev
{"title":"Features of using antihypertensive drugs by family physicians","authors":"O. A. Orazklychev, B. G. Khodzhakuliev, M. K. Kurdova, B. M. Ovezklychev","doi":"10.33920/med-13-2208-03","DOIUrl":"https://doi.org/10.33920/med-13-2208-03","url":null,"abstract":"The purpose of the study: to investigate the features of the rational use of antihypertensive drugs (AHP) by family physicians on an outpatient basis and analyze their compliance with modern international recommendations.","PeriodicalId":12259,"journal":{"name":"Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology)","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75141653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}