Experimental Aging Research最新文献_第3页

Hippocampal Subregions Volume and Texture for the Diagnosis of Mild Cognitive Impairment. 用于诊断轻度认知障碍的海马亚区体积和纹理。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2025-01-01 Epub Date: 2024-02-15 DOI: 10.1080/0361073X.2024.2313940

Tongpeng Chu, Yajun Liu, Bin Gui, Zhongsheng Zhang, Gang Zhang, Fanghui Dong, Jianli Dong, Shujuan Lin

{"title":"Hippocampal Subregions Volume and Texture for the Diagnosis of Mild Cognitive Impairment.","authors":"Tongpeng Chu, Yajun Liu, Bin Gui, Zhongsheng Zhang, Gang Zhang, Fanghui Dong, Jianli Dong, Shujuan Lin","doi":"10.1080/0361073X.2024.2313940","DOIUrl":"10.1080/0361073X.2024.2313940","url":null,"abstract":"The aim was to examine the diagnostic efficacy of hippocampal subregions volume and texture in differentiating amnestic mild cognitive impairment (MCI) from normal aging changes. Ninety MCI subjects and eighty-eight well-matched healthy controls (HCs) were selected. Twelve hippocampal subregions volume and texture features were extracted using Freesurfer and MaZda based on T1 weighted MRI. Then, two-sample t-test and Least Absolute Shrinkage and Selection Operator (LASSO) regression were developed to select a subset of the original features. Support vector machine (SVM) was used to perform the classification task and the area under the curve (AUC), sensitivity, specificity and accuracy were calculated to evaluate the diagnostic efficacy of the model. The volume features with high discriminative power were mainly located in the bilateral CA1 and CA4, while texture feature were gray-level non-uniformity, run length non-uniformity and fraction. Our model based on hippocampal subregions volume and texture features achieved better classification performance with an AUC of 0.90. The volume and texture of hippocampal subregions can be utilized for the diagnosis of MCI. Moreover, we found that the features that contributed most to the model were mainly textural features, followed by volume. These results may guide future studies using structural scans to classify patients with MCI.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"125-136"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139734803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the Utility of a Multiple Group Membership Intervention for Alleviating the Effects of Age-Based Stereotype Threat on Older adults' Memory Performance. 研究多重群体成员干预对减轻年龄刻板印象威胁对老年人记忆力影响的作用。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2025-01-01 Epub Date: 2024-01-26 DOI: 10.1080/0361073X.2024.2306457

Giverny J Parker, Catherine Haslam, Jaimee Stuart, David H K Shum, Tamara Ownsworth

{"title":"Examining the Utility of a Multiple Group Membership Intervention for Alleviating the Effects of Age-Based Stereotype Threat on Older adults' Memory Performance.","authors":"Giverny J Parker, Catherine Haslam, Jaimee Stuart, David H K Shum, Tamara Ownsworth","doi":"10.1080/0361073X.2024.2306457","DOIUrl":"10.1080/0361073X.2024.2306457","url":null,"abstract":"This study examined the effectiveness of a multiple group membership intervention for reducing the negative effects of age-based stereotype threat (ABST) on older adults' objective memory performance and subjective memory concerns. Healthy older adults (N = 68) were randomly allocated to an ABST + threat-removal (ABST+TR) or ABST + active-control (ABST+AC) condition. After activating ABST, the ABST+TR condition completed a group-listing task and the ABST+AC condition completed a meal-listing task. Participants then completed the Rey Auditory Verbal Learning Test (RAVLT) and Everyday Memory Questionnaire - Revised. One significant difference was found in memory performance between conditions; specifically, after controlling for age, gender, and number of items listed, those in the ABST+TR condition performed significantly better on the RAVLT memory interference trial. Further, listing a greater number of group memberships was associated with better memory performance in the ABST+TR condition. No significant difference was found in subjective memory concerns between the ABST+TR condition and the ABST+AC condition. Overall, the current findings indicated that raising the salience of multiple group memberships offered limited protection for older adults' cognitive test performance in the context of ABST.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"103-124"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139566943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COPD, Dietary Fiber Intake, and Cognitive Performance in Older Adults: A Cross-Sectional Study from NHANES 2011-2014. 慢性阻塞性肺病、膳食纤维摄入量和老年人认知能力:来自NHANES 2011-2014的横断面研究

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2025-01-01 Epub Date: 2023-11-27 DOI: 10.1080/0361073X.2023.2286874

Songlan Liang, Xu Han, Shuang Diao, Hui Li

{"title":"COPD, Dietary Fiber Intake, and Cognitive Performance in Older Adults: A Cross-Sectional Study from NHANES 2011-2014.","authors":"Songlan Liang, Xu Han, Shuang Diao, Hui Li","doi":"10.1080/0361073X.2023.2286874","DOIUrl":"10.1080/0361073X.2023.2286874","url":null,"abstract":"Introduction: This study aimed to evaluate the modifying role of dietary fiber intake in the relationship between COPD and cognitive performance.Methods: Data of adults aged ≥60 years were extracted from the National Health and Nutrition Examination Survey (NHANES) 2011-2014. Participants with information on cognitive function measures were included. Dietary fiber intake, identified using participants' 24-h recall surveys, was grouped into high (>25 g/day) and low (≤25 g/day) levels. COPD was identified through self-reported physician diagnoses. Associations between dietary fiber intake, cognitive function and COPD were evaluated using the regression analysis.Results: Data of 2,189 participants were analyzed. Multivariate analysis revealed that COPD was significantly associated with lowered CERAD (adjusted beta [aBeta]: -0.17, 95% confidence interval [CI]: -0.33 to -0.002, p = .047) and DSST (aBeta: -2.23, 95% CI: -4.25 to -0.2, p = .032) scores in older adults. The analysis on the association between COPD and cognitive function stratified by dietary fiber intake revealed that COPD remained significantly associated with lowered CREAD among individuals with a high fiber intake (aBeta: -0.54, 95% CI: -1.00 to -0.08, p = .024).Conclusions: In US older adults, COPD is associated with reduced cognitive function. However, the findings do not support that high dietary fiber intake may modify the association between COPD and cognitive impairment.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"92-102"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138444418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between Quality of Life and Depressive Symptoms Among Jordanian Community-Dwelling Older Adults. 约旦社区老年人生活质量与抑郁症状的关系

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2025-01-01 Epub Date: 2023-11-22 DOI: 10.1080/0361073X.2023.2286873

Malakeh Z Malak, Anas H Khalifeh

{"title":"The Relationship Between Quality of Life and Depressive Symptoms Among Jordanian Community-Dwelling Older Adults.","authors":"Malakeh Z Malak, Anas H Khalifeh","doi":"10.1080/0361073X.2023.2286873","DOIUrl":"10.1080/0361073X.2023.2286873","url":null,"abstract":"Objective: The current study aimed to examine the relationship between depressive symptoms and quality of life among Jordanian community-dwelling older adults.Methods: A cross-sectional, descriptive correlational design was used. A convenience sample (N = 602) was selected to recruit the participants in the Amman governorate during the period from August to November 2021.Results: Findings demonstrated that the mean (SD) age of older adults was 67.5 (7.0) years and 51.5% of participants were females. Also, 54.1% of the participants experienced moderate to severe depressive symptoms with a total mean (SD) score was 8.57 on a scale of 0 to 15, while the mean (SD) for the quality of life scale was 12.12 (3.85) on a scale of 4 to 20. Significant differences existed in quality of life and depressive symptoms based on marital status (p < .001), educational level (p < .001), working status (p < .01), income (p < .001), and chronic disease (p < .01). Quality of life and its domains were negatively associated with depressive symptoms (B= - 0.596, p < .001). Also, marital status, working, educational level, income, and chronic disease were associated with depressive symptoms.Conclusion: Strategies to improve quality of life should be promoted to minimize depressive symptoms among older adults and consider significant demographic factors.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"19-34"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138290693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reactive Turning Behavior in Older Adults: Age-Related Decrease is Evident under Increased Task Demand. 老年人的反应性转向行为：在任务需求增加的情况下，与年龄有关的减少显而易见。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-12-13 DOI: 10.1080/0361073X.2024.2439743

Takahito Nakamura, Yuki Suda, Takahiro Higuchi

{"title":"Reactive Turning Behavior in Older Adults: Age-Related Decrease is Evident under Increased Task Demand.","authors":"Takahito Nakamura, Yuki Suda, Takahiro Higuchi","doi":"10.1080/0361073X.2024.2439743","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2439743","url":null,"abstract":"A sudden turn initiated at an unpredictable moment is referred to as reactive turning. This study was designed to seek an age-related decrease in reactive turning when the task demand for turning was increased using a task-switching paradigm. Twenty healthy older adults and 14 younger adults were instructed to walk and execute a 90-degree turn under two conditions. In the \"reactive turning condition,\" participants were asked to turn abruptly when the initially presented travel direction (e.g. right) switched to the opposite direction (e.g. left) while walking. This switch occurred in only one-fifth of 40 trials. In the \"pre-planned turning condition,\" participants were informed of the direction beforehand. The onset of the center of mass (COM) shift in older participants failed to reach significance compared to younger participants. However, correlation analyses showed impaired turning performance in older participants, as those with delayed COM shift exhibited larger pelvic rotations over a short period during reactive turning. This suggests that, owing to increased task demand, older adults had difficulty quickly responding and sufficiently rotating their bodies in the new direction. We conclude that reactive turning with increased task demand, using a task-switching paradigm, is a key factor in detecting age-related performance decline.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-16"},"PeriodicalIF":1.4,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of the Nocturnal Sleep on Learning of a Complex Motor Skill in Young and Older Adults. 夜间睡眠对年轻人和老年人复杂运动技能学习的影响。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-12-12 DOI: 10.1080/0361073X.2024.2439741

Marina Gonçalves Leal, José Eduardo Dos Martírios Luz, Yara Lucy Fidelix, Eric Roig-Hierro, Giordano Marcio Gatinho Bonuzzi

{"title":"The Effects of the Nocturnal Sleep on Learning of a Complex Motor Skill in Young and Older Adults.","authors":"Marina Gonçalves Leal, José Eduardo Dos Martírios Luz, Yara Lucy Fidelix, Eric Roig-Hierro, Giordano Marcio Gatinho Bonuzzi","doi":"10.1080/0361073X.2024.2439741","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2439741","url":null,"abstract":"Background/study context: Research on older adults has shown impairments in nocturnal sleep, impacting motor memory consolidation and learning. However, previous studies primarily focus on simple tasks, limiting generalization to complex motor activities. Moreover, no evidence exists on how sleep influences adaptability and relearning in older adults.Methods: Sixty older adults and 60 young adults practiced an underarm dart-throwing task. The participants were divided into 2 sub-groups: SLEEP, which practiced in the evening and was retested on the morning of the following day, and CONTROL, which practiced in the morning and was retested in the evening on the same day. The practice and retention phases were spaced 12 hours. We analyzed motor learning through persistence, adaptability and relearning rate.Results: Sleep did not enhance motor learning for any group. While young adults exhibited retention, older adults did not, especially after nocturnal sleep. There was no difference between sub-groups in adaptability. Older adults demonstrated inferior relearning compared to young adults, independently of sleep.Conclusion: Nocturnal sleep did not influence memory consolidation in any group. On the contrary, our findings suggest that nocturnal sleep harms retention in older adults. Age-related characteristics induce a worse relearning rate regardless of sleep occurrence.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-14"},"PeriodicalIF":1.4,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction. 修正。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-12-09 DOI: 10.1080/0361073X.2024.2436239

引用次数: 0

The Association Between Pain and Physical Frailty Among Older Adults in India: Depression and Insomnia as Mediators. 印度老年人疼痛和身体虚弱之间的关系：抑郁和失眠作为中介。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-12-07 DOI: 10.1080/0361073X.2024.2429314

T Muhammad, Manacy Pai, Waad Ali

{"title":"The Association Between Pain and Physical Frailty Among Older Adults in India: Depression and Insomnia as Mediators.","authors":"T Muhammad, Manacy Pai, Waad Ali","doi":"10.1080/0361073X.2024.2429314","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2429314","url":null,"abstract":"Objectives: To investigate the association between body pain and physical frailty among older adults in India and to examine whether this association is mediated by symptoms of depression and insomnia.Methods: Data were obtained from the Longitudinal Aging Study in India, comprising 31,464 adults aged 60 and older. Physical frailty was assessed using a modified version of the frailty phenotype developed by Fried and colleagues. Multivariable logistic regression was used to analyze associations, and the Karlson-Holm-Breen method was employed to evaluate mediation effects.Results: The prevalence of frailty was 30.65%, with women showing a higher prevalence than men (33.16% vs. 27.85%). Older adults experiencing body pain had increased odds of frailty (adjusted odds ratio [aOR]: 1.17, 95% CI: 1.06-1.35). Depression (aOR: 1.70, 95% CI: 1.44-2.01) and insomnia symptoms (aOR: 1.58, 95% CI: 1.38-1.81) were independently associated with higher odds of frailty. Mediation analysis showed that depression mediated 8.4% of the association between pain and frailty in men and 6.11% in women. Insomnia symptoms mediated 11.47% of the association in men and 14.54% in women.Conclusion: Body pain was significantly associated with a higher likelihood of frailty among older adults in India. Symptoms of depression and insomnia partially mediated this association, with a stronger mediating effect observed for insomnia in women. Inclusive health care strategies addressing pain, depression, and insomnia could help mitigate the risk of frailty in this population.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-19"},"PeriodicalIF":1.4,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Investigation of Non-Auditory Lexical Language Skills in Relation to Hearing Ability and Second Language Use in Older Adults. 老年人非听觉词汇语言技能与听力和第二语言使用的关系研究。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-12-04 DOI: 10.1080/0361073X.2024.2432238

Margreet Vogelzang

引用次数: 0

Age Difference on the Spatial Scale of Object Categorization. 对象分类空间尺度上的年龄差异。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-11-29 DOI: 10.1080/0361073X.2024.2435779

Muriel Boucart, Quentin Lenoble, Carole Peyrin

{"title":"Age Difference on the Spatial Scale of Object Categorization.","authors":"Muriel Boucart, Quentin Lenoble, Carole Peyrin","doi":"10.1080/0361073X.2024.2435779","DOIUrl":"https://doi.org/10.1080/0361073X.2024.2435779","url":null,"abstract":"Background: As the elderly population is growing worldwide and communication is increasingly relayed by visual interfaces, identifying age-related changes in the visual perception of complex stimuli is critical. We examined the effect of spatial frequency filtering on object categorization in young (mean 25 years) and older (mean 65 years) participants.Method: The stimuli used were low spatial frequency (LSF, cutoff 8 cpi) or high spatial frequency (HSF, cutoff 24 cpi) images of objects of various categories, and hybrid images composed of a LSF object superimposed on a HSF object from a different semantic category. Participants were asked to press a key when they detected an object from a specified category (e.g., animal).Results: Young participants categorized efficiently LSF and HSF images, and exhibited a bias towards the HSF component of hybrid images. Older participants showed a better performance on LSF than on HSF images and exhibited a strong bias towards the LSF component of hybrid image.Conclusion: The results show that LSF are better preserved than HSF in older people. The greater interference of LSF than HSF in older than in young adults suggests that LSF are available earlier than HSF in older people.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-12"},"PeriodicalIF":1.4,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0