Mustafa Cemali, Mustafa Sarı, Demet Öztürk, Özgün Elmas, A Ayşe Karaduman
{"title":"Examination of the Relationship Between Sensory Processing Skills, Kinesiophobia and Fear of Falling in Older Adults with Hypertension and Normotension.","authors":"Mustafa Cemali, Mustafa Sarı, Demet Öztürk, Özgün Elmas, A Ayşe Karaduman","doi":"10.1080/0361073X.2024.2397323","DOIUrl":"10.1080/0361073X.2024.2397323","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to investigate fear of falling, kinesiophobia, and sensory processing in older adults with hypertension and normotension.</p><p><strong>Methods: </strong>Older adults, 62 with hypertension and 62 with normotension, aged 65-84 years were included in the study. The assessment of fear of falling was conducted using the Tinetti Falls Efficacy Scale, kinesiophobia was evaluated with the Tampa Kinesiophobia Scale, and sensory processing skills were analyzed with the Adolescent/Adult Sensory Profile.</p><p><strong>Results: </strong>Significant differences were found between the groups in terms of vestibular processing, visual processing and activity level, fear of falling and kinesiophobia (<i>p</i> < .05). No significant differences were found between the groups with respect to taste/smell, tactile, and auditory processing skills. The findings revealed that older adults with hypertension exhibited diminished vestibular and visual processing abilities, reduced activity levels, and heightened concerns about falling and a tendency to experience kinesiophobia. Fear of falling and kinesiophobia were found to increase with decreasing vestibular processing skills and activity levels in both groups (<i>p</i> < .05). Regression analysis revealed that age, kinesiophobia, vestibular processing, and activity levels were significant determinants of fear of falling (<i>p</i> < .05).</p><p><strong>Conclusion: </strong>It is recommended that older adults with hypertension be assessed in terms of sensory, functional, and mental health, with the objective of planning appropriate intervention approaches.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"137-149"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Community-Based Virtual Reality Interventions in Older Adults with Dementia and/or Cognitive Impairment: A Systematic Review.","authors":"Iliana Stavropoulou, Evanthia Sakellari, Anastasia Barbouni, Venetia Notara","doi":"10.1080/0361073X.2024.2377438","DOIUrl":"10.1080/0361073X.2024.2377438","url":null,"abstract":"<p><strong>Introduction: </strong>Virtual reality devices have been widely used for the rehabilitation among older people with cognitive impairments. They enable the user to navigate in three-dimensional environments, which are constructed by a computer. Recent studies have been focused on the cognitive benefits of virtual reality for people with cognitive deficits. The current study aimed to investigate the overall impact of community-based virtual reality interventions in older adults with dementia and/or cognitive impairment.</p><p><strong>Methods: </strong>A systematic review of the literature was conducted according to the PRISMA guidelines. Google Scholar, PubMed, Science Direct and Scopus databases were searched for the years 2010-2022.</p><p><strong>Results: </strong>Of the 245 articles 20 met the inclusion criteria. The results of the current systematic review indicated that virtual reality improved older adults' cognitive and motor skills and increased their positive emotions while minimizing less positive ones. However, there is insufficient data of its impact on their overall quality of life.</p><p><strong>Conclusion: </strong>There is a need to implement and evaluate interventions that examine its impact not only on cognitive functioning, but also on other aspects of older people with cognitive deficits.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"162-189"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Association Between Social Support and the Quality of Life of Older Adults in China: The Mediating Effect of Loneliness.","authors":"Nannan Jiang, Hong Ye, Xinran Zhao, Yanli Zhang","doi":"10.1080/0361073X.2024.2376966","DOIUrl":"10.1080/0361073X.2024.2376966","url":null,"abstract":"<p><strong>Background: </strong>Quality of life, social support, and loneliness are common problems among older adults in China , but the relationships among these issues have not been clearly identified.</p><p><strong>Objectives: </strong>The present study aimed to determine the relationships among Quality of life, social support, and loneliness.</p><p><strong>Methods: </strong>A total of 560 older adults were randomly selected , the social support rating scale (SSRS), University of California at Los Angeles (UCLA) loneliness scale, and Short-Form 12 (SF-12) were employed to measure their degree of social support, level of loneliness, and quality of life.</p><p><strong>Results: </strong>The average physical component summary (PCS) score was 49.97±16.33, and the average mental component summary (MCS) score was 47.26±11.49. Loneliness plays a partial mediating role between social support and quality of life.</p><p><strong>Conclusion: </strong>Loneliness and a lack of social support will affect the quality of life of the older adults. Thus, we need to urgently strengthen the care and support for the older adults and alleviate the loneliness of the older adults in the community.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"232-246"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karen Miyamoto Moriya, Vanderlei Carneiro da Silva, Angelica Castilho Alonso, José Maria Montiel, Gisele Garcia Zanca
{"title":"Is Functioning of Older Adults with Chronic Musculoskeletal Pain Related to Health Literacy?","authors":"Karen Miyamoto Moriya, Vanderlei Carneiro da Silva, Angelica Castilho Alonso, José Maria Montiel, Gisele Garcia Zanca","doi":"10.1080/0361073X.2025.2470578","DOIUrl":"https://doi.org/10.1080/0361073X.2025.2470578","url":null,"abstract":"<p><p>We investigated the relationship between health literacy (HL) and functioning among older adults with and without chronic musculoskeletal pain (CMP). In a cross-sectional study, we assessed 121 older adults with CMP and 53 without pain using WHODAS 2.0 for functioning and the Newest Vital Sign for HL assessment. Cluster analysis identified groups based on functioning levels. A decision tree model was developed, to account for nonlinear interactions. We found a relationship of inadequate HL with lower functioning in older adults with CMP, particularly when aged over 70 and those younger but with lower education levels. Findings highlight the importance of screening HL among older adults with CMP and considering it for tailoring interventions.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-15"},"PeriodicalIF":1.4,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adriana Savettiere, Peter Louras, Sarah Langdon, J Kaci Fairchild
{"title":"Identifying Biomarkers of Neuroplasticity Associated with Exercise-Induced Cognitive Change in Older Adults with MCI.","authors":"Adriana Savettiere, Peter Louras, Sarah Langdon, J Kaci Fairchild","doi":"10.1080/0361073X.2025.2470579","DOIUrl":"https://doi.org/10.1080/0361073X.2025.2470579","url":null,"abstract":"<p><strong>Objectives: </strong>This exploratory study aimed to identify biomarkers of neuroplasticity that prevent cognitive decline. This study examined activity-dependent changes in the neurologic proteome that contributed to post-exercise improvements in processing speed in older adults with mild cognitive impairment (MCI).</p><p><strong>Methods: </strong>Participants included 20 older adult Veterans with MCI recruited through the VA Palo Alto Health Care System (VAPAHCS) who participated in moderate-high intensity water-based activity thrice weekly for six months. Plasma protein concentration was measured using the Olink Target 96 Neurology Assay. Processing speed measures included the Trail Making Test Trial A (TMT-A), the Stroop Color (SC) and Word (SW) trials, and the Symbol Digit Modalities Test (SDMT).</p><p><strong>Results: </strong>Preliminary analyses revealed two proteins of interest: neuropilin-2 (NRP2) and neuroblastoma suppressor of tumorigenicity 1 (NBL1). Primary analyses used mixed effects models to determine the impact of changes in neurologic-related proteins on changes in processing speed after exercise. Results indicated that decreased levels of NRP2 were associated with improved outcomes on the SDMT after exercise. In contrast, changes in NBL1 had no significant effect on the relationship between exercise and processing speed.</p><p><strong>Conclusion: </strong>These results support previous research linking NRP2 function to synaptic plasticity downscaling and present NRP2 as a potential target for cognitive intervention.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-14"},"PeriodicalIF":1.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jovian C Lam, Peter Louras, Adriana Savettiere, J Kaci Fairchild
{"title":"Worry Moderates Plasma Placental Growth Factor (PIGF) and Cognition in Older Adults with Amnestic Mild Cognitive Impairment (aMCI).","authors":"Jovian C Lam, Peter Louras, Adriana Savettiere, J Kaci Fairchild","doi":"10.1080/0361073X.2025.2468102","DOIUrl":"https://doi.org/10.1080/0361073X.2025.2468102","url":null,"abstract":"<p><strong>Background: </strong>Elevated worry is an early indicator of cognitive decline in older adults. Worry has been linked to pro-inflammatory processes though the exact relations between worry, inflammation, and cognition in older adults with amnestic mild cognitive impairment (aMCI) remain unexplored. The present study studied the association of worry with proteomic biomarkers of inflammation and cognition.</p><p><strong>Method: </strong>Participants include 66 community-dwelling older adults with amnestic mild cognitive impairment (aMCI). Inflammation was analyzed using the modified aptamer-based assay SomaScan Platform. Primary analyses consisted of two hierarchical regression models with mean-centered worry and inflammation as independent variables and age as covariate. Composite scores of executive function and processing speed were entered as the dependent variable in separate models.</p><p><strong>Results: </strong>Results indicate a significant interaction between worry and placental growth factor (PIGF) on processing speed, such that worry intensifies the inverse relationship of PIGF and processing speed. Worry did not interact with PIGF to predict executive functioning.</p><p><strong>Conclusion: </strong>Findings indicate an important moderating role of worry in the association of pro-inflammatory PIGF and processing speed. Results suggest that older adults with cognitive impairment may be more susceptible to the indirect impact of worry and expands emerging research on the role of PIGF in cognitive impairment.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-16"},"PeriodicalIF":1.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isa Kianimotlagh, Rasool Abedanzadeh, Ayoub Hashemi
{"title":"Comparison of the Effect of Active Video Games and Transcranial Direct Current Stimulation on Executive Functions of the Elderly: A Randomized Clinical Trial Study.","authors":"Isa Kianimotlagh, Rasool Abedanzadeh, Ayoub Hashemi","doi":"10.1080/0361073X.2025.2468103","DOIUrl":"https://doi.org/10.1080/0361073X.2025.2468103","url":null,"abstract":"<p><strong>Objectives: </strong>Among the changes related to aging in the elderly, a decline in executive functions is notable. The present study aimed to investigate the comparative impact of active video games (AVG) and transcranial direct current stimulation (tDCS) on executive functions in elderly individuals in Khuzestan province, Iran.</p><p><strong>Methods: </strong>This research employed a randomized controlled trial with a pretest-posttest design, including a control group and follow-up. The statistical population comprised all elderly residents of Khuzestan province. Sixty elderly participants (60 years and above) were selected using convenience sampling and randomly assigned to three experimental groups (tDCS, AVG, tDCS + AVG) and one control group. They received interventions for 5 weeks (2 sessions per week). Data were collected using the N-back, Stroop, and Wisconsin Card Sorting tests. Data analysis was performed using mixed-ANOVA with SPSS version 25, and significance was set at <i>p</i> < .05.</p><p><strong>Results: </strong>The results of the study demonstrated that AVG and tDCS significantly improved working memory and cognitive flexibility in the elderly. Comparison between the two intervention groups indicated a greater effect of tDCS compared to AVG (<i>p</i> < .05). Additionally, the combined group showed better performance in posttest and memory follow-up compared to the other groups, although no significant difference was found in the attention component (<i>p</i> > .05).</p><p><strong>Conclusion: </strong>Engaging in AVG and tDCS can contribute to improving executive functions in the elderly. Therefore, it is recommended that these therapeutic techniques be utilized in elderly care centers to enhance the executive performance of these individuals.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-17"},"PeriodicalIF":1.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Robot-Assisted Gait Training in Older Patients with Comorbid Conditions: A Pilot Study.","authors":"Seung Ick Choi, So Jeong Lim, Na Young Kim","doi":"10.1080/0361073X.2025.2459546","DOIUrl":"https://doi.org/10.1080/0361073X.2025.2459546","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the efficacy of robot-assisted gait training (RAGT) in older patients with neurological gait disorder accompanied by various comorbidities.</p><p><strong>Materials and methods: </strong>We included Individuals aged ≥65 years with degenerative brain diseases or stroke causing gait disorders for >6 months in open-label, a pilot study. RAGT was performed for 30 min/day, 2 days/week for 12 weeks. The intensity was set to 60% of the individual's heart rate maximum reserve. Primary outcome measures were the Timed Up and Go (TUG) test and Berg Balance Scale (BBS). Secondary outcomes included Beck Depression Inventory (BDI), Short Form-36 (SF-36), and evaluation of satisfaction.</p><p><strong>Results: </strong>Thirteen participants completed 24 sessions. Neurological diseases included stroke (<i>n</i> = 7) and Parkinson's disease (<i>n</i> = 6); all patients had at least two other diseases. After RAGT, TUG test results significantly improved, and BBS scores increased. Furthermore, BDI scores decreased, and scores of social functioning and mental health domain in the SF-36 increased. Participants rated high scores on satisfaction of RAGT.</p><p><strong>Conclusions: </strong>Our finding showed that RAGT is a safe and effective intervention for enhancing physical function, improving quality of life, and reducing depression levels in older patients with neurological gait disorder accompanied by various comorbidities.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-13"},"PeriodicalIF":1.4,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zahra Khalili, Afshin Mozafarimanesh, Hadi Najafi, Ahmad Vakili-Basir, Maedeh Salehi Sarookollaei, Shahab Papi
{"title":"Association Between Oral Health Status and DMFT Index with Cognitive Dysfunction in Community-Dwelling Older Adults with Type 2 Diabetes: A Cross-Sectional Study.","authors":"Zahra Khalili, Afshin Mozafarimanesh, Hadi Najafi, Ahmad Vakili-Basir, Maedeh Salehi Sarookollaei, Shahab Papi","doi":"10.1080/0361073X.2025.2455325","DOIUrl":"https://doi.org/10.1080/0361073X.2025.2455325","url":null,"abstract":"<p><strong>Objective: </strong>Cognitive dysfunction is a significant issue in old age and can cause many problems in older adults, especially those with diabetes. This study aimed to investigate the association between oral health status and DMFT index with cognitive dysfunction in community-dwelling older adults with T2D (type 2 diabetes).</p><p><strong>Methods: </strong>This was a cross-sectional study that included 245 older people aged 60 years and older with T2D, visiting healthcare centers in north of Iran, using the cluster sampling method. Data collection tools included clinical-demographic questionnaire, the Geriatric Oral Health Assessment Index (GOHAI) and the Mini-Mental State Examination (MMSE) questionnaire. A P-value <.05 was considered significant.</p><p><strong>Results: </strong>The mean age of older adults in this study was 64.86 ± 3.99 years. The mean and standard deviation for the DMFT index, GOHAI index and MMSE scale were 9.39 ± 3.83, 34.29 ± 17.93 and 15.18 ± 10.04 respectively. The results showed statistically significant relationship between poor oral health status and the cognitive status of older adults with T2D (<i>p</i> < .001). Additionally, the relationship between oral health index domains (physical function, psychosocial function and pain) and cognitive status in older adults was significant (<i>p</i> < .001). Another finding indicated an inverse and significant relationship between the DMFT index and cognitive dysfunction in older adults (<i>p</i> < .001).</p><p><strong>Conclusion: </strong>Poor oral health was associated with cognitive dysfunction among the community-dwelling older adults with T2D. Given the high prevalence of T2D in older adults and the critical importance of oral and dental health for cognition, it is necessary to develop interventions to improve oral health in older adults with T2D.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"1-12"},"PeriodicalIF":1.4,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tara T Lineweaver, Annie C Wetli, Coty Nicoson, Ashley J Tucker, Christopher Hertzog
{"title":"Exposure to Memory-Relevant versus Memory-Irrelevant Aging Stereotypes Differentially Affects Memory Self-Perceptions and Memory Test Scores of Young, Middle, and Older Age Adults.","authors":"Tara T Lineweaver, Annie C Wetli, Coty Nicoson, Ashley J Tucker, Christopher Hertzog","doi":"10.1080/0361073X.2023.2295202","DOIUrl":"10.1080/0361073X.2023.2295202","url":null,"abstract":"<p><p>This study examined the combined influence of assimilation and contrast effects on the memory self-efficacy and objective memory of young (ages 18-25, <i>n</i> = 114), middle-age (ages 26-59, <i>n</i> = 48), and older (ages 60-98, <i>n</i> = 59) adults. We reminded participants that they matched positive, not negative, memory-relevant or memory-irrelevant stereotypes of aging either before (experimental conditions) or after (control condition) they completed a memory self-efficacy questionnaire and took a memory test. Participants exposed to memory-relevant aging stereotypes prior to other measures reported higher memory self-efficacy than those exposed to memory-irrelevant stereotypes; this effect did not depend on age group. In contrast, the effect of stereotype exposure on memory performance differed with age. Young and older, but not middle-aged, adults showed differences in their memory scores depending on whether they were exposed to memory-relevant, memory-irrelevant or no aging stereotypes. In general, exposure to stereotypes (particularly those relevant to memory) had a negative influence on memory that contrasted with its positive effect on memory self-efficacy. Together, these results indicate that exposure to aging stereotypes can have opposing effects on the memory self-efficacy and objective test performance of adults of various ages and that the relevance of the stereotypes to the cognitive domain being assessed matters.</p>","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":" ","pages":"73-91"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138829120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}