Experimental Aging Research最新文献_第2页

The Effects of Vitamin D on Movement and Cognitive Function in Senile Mice After Sevoflurane Anaesthesia. 维生素D对七氟醚麻醉后老年小鼠运动和认知功能的影响。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-11-22 DOI: 10.1080/0361073X.2023.2282350

Jialei Zhang, Xiaoling Zhang, Jun Zhao, Jie Wu

{"title":"The Effects of Vitamin D on Movement and Cognitive Function in Senile Mice After Sevoflurane Anaesthesia.","authors":"Jialei Zhang, Xiaoling Zhang, Jun Zhao, Jie Wu","doi":"10.1080/0361073X.2023.2282350","DOIUrl":"10.1080/0361073X.2023.2282350","url":null,"abstract":"Background: Vitamin D (VD) is a neuroactive steroid involved in many brain functions, such as neurotrophic, neuroimmune control and neurotransmission, which affects the growth and function of the brain. The purpose of this study is to explore the effect of VD on motor and cognitive function of aged mice after sevoflurane anesthesia.Method: We established sevoflurane anesthesia model and VD(-) and VD(+) mice model. The VD concentration of mice in each group was determined by enzyme-linked immunosorbent assay (ELISA). An open-field test was used to evaluate the mice's capacity for movement and exploration. A Y-maze test was used to gauge the mice's short-term memory. The primary purpose of the water-maze experiment was to examine mice's long-term spatial memory.Results: The ELISA results showed that the model was successfully constructed. In the open-field test, VD increased the exercise distance of mice (P < .05). In the Y-maze experiment, VD improved short-term memory impairment in mice (P < .05). In the water-maze test, VD increased the activity time and platform crossing number of mice in the target quadrant. (P < .05).Conclusion: Sevoflurane anesthesia caused cognitive dysfunction in aged mice, including reduced learning ability, memory loss, lower motor and exploratory abilities and depression, and VD deficiency aggravated these impairments. By supplementing with VD, learning ability and long-term memory were enhanced, motor and exploratory abilities were improved, and depression levels were reduced. Anxiety was also improved.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138290692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Autobiographical Resilience Memories in Emotion Regulation: An Account of Age Differences in Mnemonic and Positive Reappraisal. 自传体复原记忆在情绪调节中的作用：记忆和积极再评价的年龄差异说明

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-09-10 DOI: 10.1080/0361073X.2023.2254659

Irina Orlovsky, Rebecca E Ready, Angela Gutchess, Kristin Heideman, Bruna Martins-Klein

{"title":"The Role of Autobiographical Resilience Memories in Emotion Regulation: An Account of Age Differences in Mnemonic and Positive Reappraisal.","authors":"Irina Orlovsky, Rebecca E Ready, Angela Gutchess, Kristin Heideman, Bruna Martins-Klein","doi":"10.1080/0361073X.2023.2254659","DOIUrl":"10.1080/0361073X.2023.2254659","url":null,"abstract":"A lifetime of resilience through emotionally challenging experiences may benefit older adults, lending to emotion regulation mastery with time. Yet the influence of autobiographical experiences on momentary reappraisal, the reinterpretation of negative stimuli as more positive, has never been empirically tested. This online study examined the extent to which associating life memories of resilience with novel negative scenarios enhanced reappraisal efficacy and reduced difficulty to reappraise. Younger and older adults reappraised negative images by associating reappraisals to freely selected autobiographical resilience memories, cued autobiographical resilience memories, or by finding situational silver linings without mnemonic association (control). Changes in image emotional intensity ratings revealed no difference across reappraisal conditions for younger adults, while older adults most effectively down-regulated emotional intensity using the control reappraisal strategy. Older adults found autobiographical memories more helpful for mood regulation and less difficult to implement, and identified greater similarities between novel negative scenarios and their memories than younger adults. Surprisingly, greater similarity between resilience memories and negative images was associated with lower reappraisal efficacy for both age groups. Findings demonstrate the age-equivalent benefits of utilizing reappraisals associated with past narratives of resilience and suggest a sacrifice of immediate hedonic benefit for disproportionately greater subjective benefits with age.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10924802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10204369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Affective Touch: A Comparison Between Two Groups of Younger and Older Females. 对情感接触的评估：两组年轻女性与老年女性的比较。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-08-28 DOI: 10.1080/0361073X.2023.2250225

Carina Schlintl, Anne Schienle

{"title":"Evaluation of Affective Touch: A Comparison Between Two Groups of Younger and Older Females.","authors":"Carina Schlintl, Anne Schienle","doi":"10.1080/0361073X.2023.2250225","DOIUrl":"10.1080/0361073X.2023.2250225","url":null,"abstract":"Background: Caress-like touch activates C-tactile (CT) afferents present in the skin of humans. It is generally assumed that this type of touch provides beneficial effects throughout the lifespan. However, little is known about its processing in later adulthood. Moreover, emotional responses to interpersonal vs. self-touch have not been investigated in older adults.Method: A total of 132 females from two age groups (older: 60-96 years; younger: 18-30) participated in a well-validated method of tactile stimulation, in which CT-optimal vs. nonoptimal soft brushing (3 cm/s vs. 30 cm/s) was administered on the forearms of the participants, once by a female experimenter and once by the participant themselves. All participants rated their affective state in each of the conditions and tactile acuity was assessed.Results: Relative to the younger group, older participants rated touch as more pleasant, independent of type (CT-optimal, non-optimal) and origin (experimenter, self). In the older group, the emotional differentiation of CT-optimal vs. non-optimal touch was reduced, which was associated with reduced tactile acuity.Conclusion: This study revealed an age-dependent enhancement of the perceived pleasantness of (self)touch. Interventions with auditory-guided CT-optimal self-touch could be easily implemented as part of training programs for older adults.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10113165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How Distracting Events Influence Young and Older adults' Arithmetic Performance? 分心事件如何影响年轻人和老年人的算术成绩？

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-09-07 DOI: 10.1080/0361073X.2023.2250224

Patrick Lemaire

{"title":"How Distracting Events Influence Young and Older adults' Arithmetic Performance?","authors":"Patrick Lemaire","doi":"10.1080/0361073X.2023.2250224","DOIUrl":"10.1080/0361073X.2023.2250224","url":null,"abstract":"In this study, I investigated the role of distraction on arithmetic performance and whether this role changes with aging during adulthood. Young and older adults were asked to verify one-digit addition problems (Expt. 1) or to estimate the results of two-digit multiplication problems (Expt. 2). In both experiments, true and false simple problems (Expt. 1) or easier and harder complex problems (Expt. 2) were displayed superimposed or not on irrelevant, emotionally neutral pictures (e.g. mushrooms). In both simple and complex arithmetic, young and older adults obtained poorer arithmetic performance under distraction relative to no-distraction conditions. Most interesting, deleterious effects of irrelevant stimuli on arithmetic performance were larger in older than in young adults. Moreover, magnitude of distraction effects increased with longer solution latencies in young (but not in older) adults while solving complex arithmetic problems. These findings have important implications for furthering our understanding of the role of distraction on cognitive performance in general, and arithmetic performance in particular, as well as age-related differences in this role.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10161785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Behavioral and Neurological Effects of Edaravone and Noscapine in Albino Wistar Rats. 依达拉奉和诺卡平对白化 Wistar 大鼠行为和神经系统的影响

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-08-24 DOI: 10.1080/0361073X.2023.2250227

Mamsa Rumaiza Hafizur Rehman, Angel Pavalu Godad, Gaurav Mahesh Doshi

引用次数: 0

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-07-29 DOI: 10.1080/0361073X.2023.2241333

Eva Marie Wieschen, Aalim Makani, Stefan T Radev, Andreas Voss, Julia Spaniol

{"title":"Age-Related Differences in Decision-Making: Evidence Accumulation is More Gradual in Older Age.","authors":"Eva Marie Wieschen, Aalim Makani, Stefan T Radev, Andreas Voss, Julia Spaniol","doi":"10.1080/0361073X.2023.2241333","DOIUrl":"10.1080/0361073X.2023.2241333","url":null,"abstract":"Older adults tend to exhibit longer response times than younger adults in choice tasks across cognitive domains, such as perception, attention, and memory. The diffusion model has emerged as a standard model for analyzing age differences in choice behavior. Applications of the diffusion model to choice data from younger and older adults indicate that age-related slowing is driven by a more cautious response style and slower non-decisional processes, rather than by age differences in the rate of information accumulation. The Lévy flight model, a new evidence accumulation model that extends the diffusion model, was recently developed to account for differences in response times for correct and error responses. In the Lévy flight model, larger jumps in evidence accumulation can be accommodated compared to the diffusion model. It is currently unknown whether younger and older adults differ with respect to the jumpiness of evidence accumulation. In the current study, younger and older adults (N = 40 per age group) completed a letter-number-discrimination task. Results indicate that older adults show a more gradual (less \"jumpy\") pattern of evidence accumulation compared to younger adults. Implications for research on cognitive aging are discussed.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9891985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Investigation of Affective Personality Traits in Alzheimer's Disease: SEEKING as a Possible Predictor for Early-Stage Alzheimer's Dementia. 阿尔茨海默氏症患者的情感人格特质调查：SEEKING 作为早期阿尔茨海默氏症痴呆症的可能预测因子。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-09-11 DOI: 10.1080/0361073X.2023.2256629

Ezgi Soncu Buyukiscan, Elif Yildirim, Asli Demirtas-Tatlidede, Basar Bilgic, Hakan Gurvit

{"title":"An Investigation of Affective Personality Traits in Alzheimer's Disease: SEEKING as a Possible Predictor for Early-Stage Alzheimer's Dementia.","authors":"Ezgi Soncu Buyukiscan, Elif Yildirim, Asli Demirtas-Tatlidede, Basar Bilgic, Hakan Gurvit","doi":"10.1080/0361073X.2023.2256629","DOIUrl":"10.1080/0361073X.2023.2256629","url":null,"abstract":"Objective: The aim of the current study was to investigate affective personality traits in Alzheimer's disease, a neurodegenerative condition mainly characterized by episodic memory impairment.Method: The sample included 69 participants from 3 diagnostic categories. Twenty-five participants were diagnosed with subjective cognitive impairment (SCI), 26 participants were diagnosed with mild cognitive impairment of the amnestic type (aMCI), and the remaining 18 participants were diagnosed with early-stage Alzheimer's dementia (ADD). Diagnostic labels were given as a result of detailed neurological, neuropsychological, and neuroradiological assessment. Affective personality traits were assessed via Affective Neuroscience Personality Scales (ANPS).Results: The only significant intergroup difference was obtained for the SEEKING subscale of ANPS. Here, ADD group scored significantly lower compared to the SCI group. The results of logistic regression analysis also indicated that SEEKING score successfully predicted early-stage ADD diagnosis.Conclusion: The results suggest that a specific personality constellation characterized by reduced investment in the outside world might be associated with Alzheimer's disease, either as a risk factor or a byproduct of the neurodegenerative process initiated by AD pathology.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10214922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low 25-Hydroxyvitamin D [25(OH)D] Levels as a Predictor of Depressive Symptoms: Evidence from Community-Dwelling Older Adults Population in Mexico City. 低25-羟基维生素D[25（OH）D]水平作为抑郁症状的预测因素：来自墨西哥城社区居住老年人的证据。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-10-13 DOI: 10.1080/0361073X.2023.2269803

Graciela Llanos-Becerra, Eduardo Dávila-Godínez, Norma Torres-Carrillo, Oscar Rosas-Carrasco, Elena Sandoval-Pinto, Raúl Beltrán-Ramírez, Nora Magdalena Torres-Carrillo

{"title":"Low 25-Hydroxyvitamin D [25(OH)D] Levels as a Predictor of Depressive Symptoms: Evidence from Community-Dwelling Older Adults Population in Mexico City.","authors":"Graciela Llanos-Becerra, Eduardo Dávila-Godínez, Norma Torres-Carrillo, Oscar Rosas-Carrasco, Elena Sandoval-Pinto, Raúl Beltrán-Ramírez, Nora Magdalena Torres-Carrillo","doi":"10.1080/0361073X.2023.2269803","DOIUrl":"10.1080/0361073X.2023.2269803","url":null,"abstract":"Objective: The purpose of this study was to assess the association between serum 25-hydroxyvitamin D [25(OH)D] levels and depressive symptoms in Mexican older adults 70 years and older.Methods: A total of 326 adults aged 70 or older from Coyoacán Cohort Study were included in this study. The depressive symptoms were assessing by Center for Epidemiologic Studies Depression Scale (CES-D) and serum 25-hydroxyvitamin D [25(OH)D] levels were measured by commercially available enzyme-linked immunosorbent assay (ELISA).Results: Overall, the prevalence of depressive symptoms was 36.5%. The mean age was 79 years, and 53.4% were women. The total serum 25-hydroxyvitamin D [25(OH)D] levels were lower in older adults with depressive symptoms when compared with older adults without depressive symptoms (p = .006). Logistic regression models showed a significant association between low serum 25(OH)D levels and depressive symptoms even after adjusting for potential confounders (OR = 2.453; 95% CI:1.218-4.939; p = .012). In addition, linear regression model to predict the effect of 25-hydroxyvitamin D [25(OH)D] levels on the CES-D score as a continuous variable, was statistically significant [F(1,324) = 8.54, p = .004], and the R-squared value was .026, indicating that this regression model explains 2.6% of the change in the CES-D score.Conclusion: These results suggest that older Mexican adults with lower serum 25-hydroxyvitamin D [25(OH)D] levels are at higher risk of presenting depressive symptoms.","PeriodicalId":12240,"journal":{"name":"Experimental Aging Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41196038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Interviewer Age on the Reminiscence Bump in Older adults' Autobiographical Memories. 采访者年龄对老年人自传记忆中回忆起伏的影响。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-11-06 DOI: 10.1080/0361073X.2023.2269802

Yoko Sakata

引用次数: 0

Effect of Perceptions of Future Time on Implicit and Explicit Memory in Older Adults. 对未来时间的感知对老年人内隐和外显记忆的影响。

IF 1.4 4区医学

Experimental Aging Research Pub Date : 2024-10-01 Epub Date: 2023-11-07 DOI: 10.1080/0361073X.2023.2269801

Aurélia Bugaiska, Patrick Bonin, Julie Ferreira, Arnaud Witt

引用次数: 0