Spousal Education and Epigenetic Age Among Partnered Older Adults in the United States.

IF 1.4 4区医学 Q4 GERIATRICS & GERONTOLOGY

Experimental Aging Research Pub Date : 2025-06-04 DOI:10.1080/0361073X.2025.2515547

Manacy Pai, Yan-Liang Yu

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引用次数: 0

Abstract

Objectives: This study examined (1) the association between spousal education and epigenetic age acceleration among US older adults, and (2) whether this varies by their own education level and marital history.

Methods: Data from the 2016 Health and Retirement Study were utilized to explore the associations between spousal education and epigenetic age acceleration, measured with four second- and third-generation epigenetic clocks (i.e. GrimAge, PhenoAge, Zhang and DunedinPoAm38).

Results: Higher spousal education was associated with slower epigenetic aging in three of the four clocks, but only among individuals with at least 12 years of education. Moreover, the association between spousal education and slower epigenetic aging, particularly with the GrimAge clock, was stronger among those previously divorced or widowed.

Discussion: These findings imply well-educated spouses play a crucial role in slowing biological aging, underscoring the value of leveraging spousal education as an asset in managing later-life health and addressing age-related health disparities.

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美国有伴侣的老年人的配偶教育和表观遗传年龄。

目的：本研究考察了(1)美国老年人的配偶教育程度与表观遗传年龄加速之间的关系，以及(2)这种关系是否因其自身的教育水平和婚姻史而异。方法：利用2016年健康与退休研究的数据，通过四个第二代和第三代表观遗传时钟（GrimAge、PhenoAge、Zhang和DunedinPoAm38）来测量配偶教育与表观遗传年龄加速之间的关系。结果：配偶受教育程度越高，四个时钟中有三个时钟的表观遗传衰老速度越慢，但仅限于受教育程度至少为12年的个体。此外，配偶受教育程度与较慢的表观遗传衰老之间的联系，尤其是与格里麦格时钟之间的联系，在离婚或丧偶的人群中更为明显。讨论：这些发现表明，受过良好教育的配偶在减缓生物衰老方面发挥着至关重要的作用，强调了利用配偶教育作为管理晚年健康和解决与年龄有关的健康差距的资产的价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Experimental Aging Research 医学-老年医学

CiteScore

3.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Experimental Aging Research is a life span developmental and aging journal dealing with research on the aging process from a psychological and psychobiological perspective. It meets the need for a scholarly journal with refereed scientific papers dealing with age differences and age changes at any point in the adult life span. Areas of major focus include experimental psychology, neuropsychology, psychobiology, work research, ergonomics, and behavioral medicine. Original research, book reviews, monographs, and papers covering special topics are published.