Eurosurveillance最新文献

{"title":"Poliovirus detections in Europe - urgent action needed to keep Europe polio-free.","authors":"Pamela Rendi-Wagner, Hans Kluge","doi":"10.2807/1560-7917.ES.2025.30.4.2500076","DOIUrl":"10.2807/1560-7917.ES.2025.30.4.2500076","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 4","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outbreak of hantavirus disease caused by Puumala virus, Croatia, 2021.","authors":"Mari Rončević Filipović, Zlatko Trobonjača, Đurđica Cekinović Grbeša, Marinko Filipović, Melita Kukuljan, Ena Mršić, Vanja Tešić, Stela Živčić-Ćosić","doi":"10.2807/1560-7917.ES.2025.30.3.2400127","DOIUrl":"10.2807/1560-7917.ES.2025.30.3.2400127","url":null,"abstract":"<p><p>In 2021, a large outbreak of hantavirus disease (HAVID) in Croatia with 334 notified cases coincided with a COVID-19 wave and included patients from areas previously not considered endemic, challenging HAVID recognition and patient management. We analysed clinical and epidemiological data on all 254 patients with HAVID treated in the Clinical Hospital Center Rijeka (CHC Rijeka) between February and November 2021. Most patients (n = 246; 96.9%) had antibodies against Puumala virus, 212 (83.5%) were residents of endemic areas for HAVID, 93 (36.6%) reported occupational exposure and 86 (33.9%) had observed rodents or rodent excreta. Thirty-seven (14.6%) patients were not notified to the public health authorities. Most patients (n = 177; 69.7%) were male. The median age of the patients was 43 years (range: 17-79 years) in males and 54 years (range: 14-77 years) in females. More severe courses of disease were observed in males aged < 45 years than in older males and females of any age (OR = 2.27; 95% CI: 1.21-4.24; p < 0.005). Measures to prevent exposure, early detection and notification of cases and close collaboration between primary and secondary healthcare teams with public health personnel are essential to improve surveillance and prevent hantavirus outbreaks.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 3","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11914960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection and characterisation of high pathogenicity avian influenza virus (H5N1/H5N8) clade 2.3.4.4b, Hong Kong SAR, China, 2021 to 2024.","authors":"Wanying Sun, Ka Tim Choy, Ka Man Cheng, Christopher J Brackman, Samuel Ms Cheng, Thomas Hc Sit, Anne Cn Tse, Leslie D Sims, Haogao Gu, Amy Wy Tang, Andrew Nc Wong, Andrew Tl Tsang, Joe Ct Koo, Leo Lh Luk, Hui-Ling Yen, Malik Peris, Leo Lm Poon","doi":"10.2807/1560-7917.ES.2025.30.1.2400839","DOIUrl":"10.2807/1560-7917.ES.2025.30.1.2400839","url":null,"abstract":"<p><p>We isolated three genotypes of highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b from wild birds infected with H5N1 (n = 12) and H5N8 (n = 1) in Hong Kong SAR 2021-2024. Viruses from two spoonbills from late 2022 were genetically related to a virus from a human in China. Four tested viruses exhibited variable virulence in mice but were susceptible to approved antivirals. No neutralising antibody was detected in 63 age-stratified human sera, suggesting potential risk should the virus adapt to humans.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 1","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11719804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum for Euro Surveill. 2024;29(50).","authors":"","doi":"10.2807/1560-7917.ES.2025.30.1.250109e","DOIUrl":"10.2807/1560-7917.ES.2025.30.1.250109e","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 1","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11719801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring SARS-CoV-2 variants with complementary surveillance systems: risk evaluation of the Omicron JN.1 variant in France, August 2023 to January 2024.","authors":"Adriana Traore, Kelly Charniga, Sophie Grellet, Garance Terpant, Héléna Da Cruz, Anais Lamy, Nathalie Thomas, Gwladys Gbaguidi, Alizé Mercier, Julie Prudhomme, Benoit Visseaux, Vincent Vieillefond, Stéphanie Haim-Boukobza, Jean-Marc Giannoli, Javier Castro-Alvarez, Alain-Claude Kouamen, Marie-Anne Rameix-Welti, Samar Beirrera-Ibraim, Gregory Destras, Laurence Josset, Simon Cauchemez, Bruno Lina, Bruno Coignard, Justine Schaeffer, Vincent Enouf, Antonin Bal","doi":"10.2807/1560-7917.ES.2025.30.1.2400293","DOIUrl":"10.2807/1560-7917.ES.2025.30.1.2400293","url":null,"abstract":"<p><p>BackgroundEarly detection and characterisation of SARS-CoV-2 variants have been and continue to be essential for assessing their public health impact. In August 2023, Santé publique France implemented enhanced surveillance for BA.2.86 and sub-lineage JN.1 because of their genetic divergence from other variants and increased prevalence.AimTo detail how combining epidemiological and laboratory data sources, targeted investigations and modelling enabled comprehensive characterisation of sub-lineage JN.1.MethodsData were collected from epidemiological investigations using a standardised questionnaire and from routine and novel (RELAB network) surveillance systems. JN.1 cases were compared with cases infected with previously circulating variants, such as EG.5, BA.4/BA.5 and other BA.2.86 sub-lineages. The growth rate and doubling time of JN.1 were estimated.ResultsJN.1 was first detected in September 2023 in the Île-de-France region, France, and spread widely across the country. By late November, doubling time was estimated to be 8.6 to 26.4 days depending on the region. For all data sources, cases infected by JN.1 showed similar demographics, rates of hospitalisation and RT-PCR cycle threshold values compared with those infected by previous variants. JN.1 cases also had older median age (54 years; 40-71 vs 47 years; 30-59), more frequent reports of feverish feeling and less frequent cough or nausea compared with BA.4/BA.5 cases. JN.1 cases had significantly higher frequency of anosmia compared with other BA.2.86 cases.ConclusionCombining different data sources played a key role in detecting emerging variant JN.1, for which no evidence of increased public health impact was found despite its genetic divergence.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 1","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11719805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of vaccine-derived poliovirus type 2 from sewage samples and public health response, Poland, November to December 2024.","authors":"Magdalena Wieczorek, Beata Gad, Arleta Krzysztoszek, Paulina Kłosiewicz, Kinga Oleksiak, Bartosz Zaborski, Paweł Grzesiowski, Katarzyna Tkaczuk, Anna Baumann-Popczyk","doi":"10.2807/1560-7917.ES.2025.30.1.2400805","DOIUrl":"10.2807/1560-7917.ES.2025.30.1.2400805","url":null,"abstract":"<p><p>In October and December 2024, circulating vaccine-derived poliovirus type 2 (cVDPV2) was detected from two wastewater samples in Poland during routine environmental surveillance. The first isolate was characterised and matched previous cVDPV2 isolates detected in Spain in September, as well as in Germany, Finland, and the United Kingdom in November and December 2024. In response to the event, active surveillance for acute flaccid paralysis (AFP) has been strengthened, and the frequency of environmental sample collection has been increased.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 1","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11719809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal acute liver failure cases with echovirus 11 infections, Japan, August to November 2024.","authors":"Tatsuki Ikuse, Toshihiro Matsui, Kensuke Shoji, Naoko Kono, Masaki Yamada, Chikara Ogimi, Chika Takahashi, Takanori Funaki, Kentaro Ide, Shotaro Matsumoto, Reiko Ito, Rinshu Shimabukuro, Yoshihiro Gocho, Itaru Hayakawa, Takashi Ishikawa, Seisuke Sakamoto, Mureo Kasahara, Takashi Igarashi","doi":"10.2807/1560-7917.ES.2025.30.1.2400822","DOIUrl":"10.2807/1560-7917.ES.2025.30.1.2400822","url":null,"abstract":"<p><p>In 2022-23, several European countries reported paediatric acute liver failure (ALF) with enterovirus infection. In August-November 2024, three neonatal cases of ALF with echovirus 11 (E11) were reported in Tokyo, Japan. All neonates developed irreversible multiple-organ failure and died. The E11 strain belonged to the new lineage 1, which was the same as strains isolated from neonatal ALF cases in Europe in 2022-23.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 1","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11719806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One health investigation following a cluster of Crimean-Congo haemorrhagic fever, North Macedonia, July to November 2023.","authors":"Dejan Jakimovski, Pavle Banović, Katerina Spasovska, Goran Rangelov, Marija Cvetanovska, Fadil Cana, Verica Simin, Ivana Bogdan, Dragana Mijatović, Aleksandar Cvetkovikj, Igor Djadjovski, Iva Christova, Eleftherios Meletis, Polychronis Kostoulas, Brigitta Zana, Zsófia Lanszki, Tamás Görföl, Zsófia Tauber, Gabor Kemenesi","doi":"10.2807/1560-7917.ES.2025.30.4.2400286","DOIUrl":"10.2807/1560-7917.ES.2025.30.4.2400286","url":null,"abstract":"<p><p>BackgroundCrimean-Congo haemorrhagic fever (CCHF) is a severe illness characterised by fever, bleeding and high case-fatality rates. The disease is caused by CCHF virus (CCHFV), transmitted by ticks and infectious body fluids and tissues.AimAfter CCHF was diagnosed in three persons in 2023, we aimed to investigate the presence of antibodies against CCHFV in healthcare workers (HCW), sheep and goats, and of CCHFV in ticks, in an area in North Macedonia and characterise virus strains.MethodsIn 2023, we collected blood samples from HCWs involved in treating CCHF patients and sera and ticks from sheep and goats in the village in North Macedonia where the index case resided. The blood samples were analysed by ELISA. Ticks were tested for presence of CCHFV, and the virus from a CCHF case was sequenced.ResultsSamples from four of 52 HCWs and 10 of 17 small ruminants had antibodies against CCHFV. The virus was not detected from any of the 24 <i>Rhipicephalus bursa</i> ticks. The virus strain from the index case clustered with regional strains within the Europe-1 lineage (genotype V) group and was closest to strains from Kosovo‡.ConclusionThis report shows CCHFV is endemic in North Macedonia. Raising awareness of the risk factors and educating people about the measures they can take to reduce exposure to the virus is important. Healthcare workers need to be aware of the disease. Early detection, robust diagnostic methods, surveillance and collaborative efforts are necessary to prevent and control CCHF in the affected regions.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 4","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple variants of tick-borne encephalitis virus in voles, mice and ticks, the Netherlands, 2021 to 2023.","authors":"Emily L Pascoe, Julian W Bakker, Sara R Wijburg, Ankje de Vries, Hein Sprong, Matteo Marcantonio, Daniel Lang, Gerhard Dobler, Clara F Köhler, Helen J Esser, Constantianus Jm Koenraadt","doi":"10.2807/1560-7917.ES.2025.30.4.2400247","DOIUrl":"10.2807/1560-7917.ES.2025.30.4.2400247","url":null,"abstract":"<p><p>BackgroundTick-borne encephalitis (TBE) can be a severe neurological disease. Identifying ecological factors that may facilitate tick-borne encephalitis virus (TBEV) circulation in the Netherlands could improve awareness and detection.AimWe aimed to identify ecological factors affecting TBEV circulation in the Netherlands and to determine if there is sustained circulation and spread of the virus.MethodsBetween June and September 2021, rodents and ticks from three previously TBEV-positive locations were tested for TBEV by PCR. We sequenced TBEV and compared the sequences with previous and subsequent sequences from the Netherlands and other countries to investigate the spread of TBEV-variants.ResultsWe captured 383 rodents, 928 feeding ticks and 1,571 questing <i>Ixodes</i> ticks and detected TBEV from six (three <i>Apodemus sylvaticus</i> and three <i>Clethrionomys glareolus</i>) (2.9%) of 206 tested rodents and two (0.9%) of 215 questing tick pools. Detection of TBEV was associated with questing tick density (Mann-Whitney U test  = 81.5; 95% confidence interval (CI): - 3.7-6.3 × 10-5; p = 0.05). Tick larvae (odds ratio (OR) = 9.0; 95% CI: 2.8-38.2; p < 0.01) and nymphs (OR = 3.8; 95% CI: 1.3-13.6; p < 0.01) were more frequent on <i>A. sylvaticus</i> than on <i>C. glareolus.</i> Sequence comparisons suggest multiple introductions and local circulation of TBEV but no spread among locations.ConclusionTick-borne encephalitis virus occurs in diverse woodlands in the Netherlands, posing a risk to those frequenting these areas. Surveillance for the early detection and monitoring of TBEV spread, along with public awareness campaigns on preventive measures, should continue. Recognition of TBE symptoms and supportive diagnostics should be made available nationwide.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 4","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges of the public health response to a rare case of non-autochthonous <i>Mycobacterium leprae</i>, Ireland, 2024.","authors":"Rebecca Marshall, Eddie Horgan, Hugh Duane, Annette Dillon, Nadra Nurdin, Sarah O'Connell, Corinna Sadlier, Anne Dee, Anne Sheahan, Peter Barrett","doi":"10.2807/1560-7917.ES.2025.30.3.2500033","DOIUrl":"10.2807/1560-7917.ES.2025.30.3.2500033","url":null,"abstract":"<p><p>This case report details the public health response to a multibacillary leprosy case in Ireland. The case presented with hypopigmented skin lesions and neurological symptoms. Challenges included delayed recognition in the clinical setting, contact tracing within a congregate setting and lack of specific Irish guidelines. Comprehensive contact tracing, chemoprophylaxis and follow-up care were implemented, guided by international protocols. This case underscores the need for tailored guidelines and stigma mitigation strategies for this neglected tropical disease in non-endemic regions.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 3","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11914959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}