Eurosurveillance最新文献

{"title":"Evaluation of European severe acute respiratory infection (SARI) surveillance, 27 European countries, 2022/23.","authors":"Diogo Fp Marques, Dory Kovacs, Miguel-Angel Sanchez-Ruiz, Ana Paula Rodrigues, Ausenda Machado, Clara Mazagatos, Susana Monge, Lisa Domegan, Joan O'Donnell, Mariette Hooiveld, Hanne-Dorthe Emborg, Baltazar Nunes, Carlos Carvalho, Angela Mc Rose","doi":"10.2807/1560-7917.ES.2025.30.20.2400655","DOIUrl":"10.2807/1560-7917.ES.2025.30.20.2400655","url":null,"abstract":"<p><p>BackgroundBetween 2020 and 2023, ECDC has supported 21 of 30 EU/EEA and six Western Balkan countries by enhancing severe acute respiratory infection (SARI) surveillance to monitor trends, detect unexpected events, evaluate public health interventions, identify risk factors and support vaccine effectiveness studies. Using diverse strategies, countries have implemented SARI surveillance and reported data at national/European levels.AimWe evaluated European-level SARI surveillance and provided recommendations to achieve objectives and improve key attribute performance.MethodsWe analysed 2022/23 surveillance data for completeness. We administered a questionnaire, targeting country-level representatives, to evaluate surveillance attributes (meeting objectives, usefulness, acceptability, timeliness, representativeness) and identify strengths, weaknesses, opportunities and threats.ResultsThirteen countries (13/27) reported data at European level. Data showed good overall completeness but varied across countries and some variables need improvement (vaccination, sequencing). The questionnaire was completed by all 27 countries. Most countries (23/27) reported that the system effectively monitored trends and considered it useful and acceptable (25/27), but only 16 found it timely and 14 representative. Challenges included insufficient case-based data, data linkage issues and insufficient data completeness. Slow/inefficient manual data extraction affected timeliness, while insufficient geographical coverage affected representativeness. Multi-pathogen surveillance was identified as the main strength, heterogeneity of systems the main weakness, improvements of hospital information systems the main opportunity, and lack of sustainable funding the main threat.ConclusionsSARI surveillance was perceived as effective in monitoring trends, useful and acceptable. To achieve additional objectives and enhance timeliness and representativeness, we recommend improving data completeness, digitalisation/automation and geographical coverage.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 20","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Users' experience of frameworks to support evidence-informed decision-making in public health: a scoping review.","authors":"Javier Bracchiglione, Yang Song, Jose F Meneses-Echávez, Helena de Carvalho Gomes, Barbara Albiger, Ivan Solà, David Rigau, Pablo Alonso-Coello","doi":"10.2807/1560-7917.ES.2025.30.19.2400184","DOIUrl":"10.2807/1560-7917.ES.2025.30.19.2400184","url":null,"abstract":"<p><p>BackgroundEvidence-informed decision-making in public health (PH) is a complex process requiring the consideration of multiple perspectives and contextual factors. Evidence-to-decision (EtD) frameworks are structured approaches aiming to improve decision-making by considering critical criteria, but users' experience has not been systematically synthesised.AimWe aim to summarise users' experiences of EtD frameworks used for PH.MethodsAs part of a broader scoping review, we identified 15 EtD frameworks for PH decision-making. We searched MEDLINE and Health Systems Evidence, conducted a hand search and citation search strategy for documents reporting users' experience of EtD frameworks and surveyed key stakeholders. We conducted a descriptive thematic synthesis, identifying main barriers and facilitators, complementing with surveys to relevant stakeholders.ResultsWe identified 12 studies reporting users' experience of two EtD frameworks: Grading of Recommendations Assessment, Development and Evaluation (n = 9) and World Health Organization INTEGRATe Evidence (n = 3). Both were perceived as structured approaches that enhanced the use of evidence while including contextual factors and facilitating consensus-building processes. Main barriers were lack of high-quality evidence for the effectiveness of PH interventions, limitations of the terminology or unclear boundaries between specific criteria, perceptions of missing criteria and the need for more guidance. Survey responses (n = 13) were consistent with these findings.ConclusionUsers of the two frameworks had an overall positive perception of the approaches, but several barriers remain. These experiences may change over time as the frameworks evolve. There is an evidence gap regarding users' experience for other EtD frameworks.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 19","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12083067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coxsackievirus B4 (CV-B4) linked to four severe neonatal infections including one fatal, Northern Ireland, October 2024 to February 2025.","authors":"Susan A Feeney, Marie Clare Crilly, Sharon Christie, Julie Lewis, Anne Eilis McColgan, Marc Niebel, James P McKenna","doi":"10.2807/1560-7917.ES.2025.30.21.2500317","DOIUrl":"10.2807/1560-7917.ES.2025.30.21.2500317","url":null,"abstract":"<p><p>We report four cases of severe neonatal non-polio enterovirus infection, requiring hospital admission. Infants presented to different regional hospitals across Northern Ireland from late 2024 to early 2025. Three had neonatal meningitis and one showed rapid demise, leading to sepsis, multi-organ failure and death at day 6 of life. All infants were less than 18 days old at presentation, two were considered congenital infections, with one presenting symptoms at birth. All infants had detectable enterovirus RNA, typed as coxsackievirus B4.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 21","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum for Euro Surveill. 2025;30(16).","authors":"","doi":"10.2807/1560-7917.ES.2024.30.17.250501e","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2024.30.17.250501e","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 17","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multi-country outbreak of <i>Salmonella</i> Mbandaka linked to pre-cooked, frozen chicken meat in ready-to-eat products, Finland, 2022 to 2023.","authors":"Ana Cristina Gonzalez-Perez, Heidi Landgren, Anni Vainio, Wioleta Kitowska, Annika Pihlajasaari, Elina Leinonen, Henry Kuronen, Taru Lienemann, Heli Tapanainen, Niina E Kaartinen, Jelena Rjabinina, Jelena Sõgel, Ruska Rimhanen-Finne","doi":"10.2807/1560-7917.ES.2025.30.17.2400602","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2025.30.17.2400602","url":null,"abstract":"<p><p>In May 2022, the Finnish Institute for Health and Welfare observed an increase in <i>Salmonella</i> Mbandaka cases. Whole genome sequencing (WGS) linked the outbreak strain to a previously reported strain in the United Kingdom. From April 2022 to January 2023, 97 cases were reported across 18 of Finland's 21 hospital districts, with a median age of 27 years (range <1-74 years) and 61% female cases. Based on trawling interviews and national food consumption data, cases were more likely to have eaten at a restaurant or takeaway (odds ratio (OR) = 115; 95% confidence interval (CI): 52-256; p < 0.001) or consumed poultry products (OR = 28; 95% CI: 7-115; p < 0.001). A case-case study linked cases with consumption of ready-to-eat products containing chicken from a specific company (OR = 28; 95% CI: 1.9-1,361; p = 0.004). Traceback investigations identified a pre-cooked, frozen chicken meat product from a country outside the European Union as the likely source. <i>Salmonella</i> Mbandaka was isolated from cases and linked by WGS to this chicken meat product. Our findings highlight the potential health risk of pre-cooked chicken meat containing <i>Salmonella</i> and the value of case-case studies and product images to assist recall during food-borne outbreak investigations.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 17","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Air and surface sampling for clade Ib monkeypox virus in United Kingdom hospitals, 2024 to 2025.","authors":"Barry Atkinson, Susan Gould, Ian Nicholls, Khanzadi Nazneen Manzoor, Jack Smith, Andrew J Hindle, Anne J Tunbridge, Joby Cole, Paul Collini, Alejandra Alonso, Geraldine O'Hara, Cecilia Tuudah, Jonathan A Otter, Berkin Hack, Caroline Taylor, Thomas Pottage, Tom Fletcher, Jake Dunning","doi":"10.2807/1560-7917.ES.2025.30.19.2500288","DOIUrl":"10.2807/1560-7917.ES.2025.30.19.2500288","url":null,"abstract":"<p><p>Air and surface sampling was performed in isolation rooms of seven patients with clade Ib mpox admitted to high consequence infectious disease centres in the United Kingdom. We detected monkeypox virus (MPXV) DNA in 66/90 surfaces samples and 1/14 air samples; replication competent MPXV was identified in 4/21 surface samples selected for viral isolation. These findings demonstrate that viable clade Ib MPXV contamination can occur during treatment of clade Ib mpox patients reinforcing the importance of infection prevention and control measures.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 19","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12083069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic impact of RSV infections in young children attending primary care: a prospective cohort study in five European countries, 2021 to 2023.","authors":"Valérie Dv Sankatsing, Sarah F Hak, Joanne G Wildenbeest, Roderick P Venekamp, Mauro Pistello, Caterina Rizzo, Santiago Alfayate-Miguélez, Daan Van Brusselen, Marta Carballal-Mariño, Uy Hoang, Rolf Kramer, Simon de Lusignan, Oliver Martyn, Marc Raes, Adam Meijer, Jojanneke van Summeren","doi":"10.2807/1560-7917.ES.2025.30.20.2400797","DOIUrl":"10.2807/1560-7917.ES.2025.30.20.2400797","url":null,"abstract":"<p><p>BackgroundData on economic costs of respiratory syncytial virus (RSV) infections among children in primary care are scarce, although most RSV-infections are managed in this setting.AimTo estimate outpatient costs for RSV-positive children aged < 5 years.MethodsIn the RSV ComNet prospective cohort, children < 5 years with acute respiratory infection were recruited for RSV testing through primary care physicians in Belgium, Italy, the Netherlands, Spain and the United Kingdom (UK) during RSV seasons 2020/21 (UK only), 2021/22 and 2022/23. Outpatient healthcare utilisation and parental work absence were assessed over 30 days through parental questionnaires. Average costs per RSV episode were calculated from outpatient healthcare sector and societal perspectives, stratified by country and age.ResultsWe included 3,414 children and 1,124 (33%) tested RSV-positive. Physicians completed reports for 878 episodes, with follow-up questionnaire data for 819 (93%). Outpatient costs ranged from EUR 97 (95% CI: 91-104) in the Netherlands to EUR 300 (95% CI: 287-312) in Spain and were higher for infants than children aged 1-5 years. Societal costs ranged from EUR 454 (95% CI: 418-494) in the UK to EUR 994 (95% CI: 938-1,053) in Belgium. For children aged 1-5 years, societal costs were primarily driven by parental work absence. In infants, the main societal cost driver varied by country, but overall outpatient healthcare costs represented a higher proportion of societal costs vs older children.ConclusionRSV infections in children attending primary care result in substantial economic costs per episode, although differences exist across countries. This study provides essential data to inform cost-effectiveness analyses on novel RSV immunisations.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 20","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addendum for Euro Surveill. 2025;30(21).","authors":"","doi":"10.2807/1560-7917.ES.2025.30.21.250529A","DOIUrl":"10.2807/1560-7917.ES.2025.30.21.250529A","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 21","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological characteristics and trends of notified enteric fevers in Germany, 2001 to 2023.","authors":"Julia Enkelmann, Sandra Simon, Eva Trost, Klaus Stark, Christina Frank","doi":"10.2807/1560-7917.ES.2025.30.14.2400314","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2025.30.14.2400314","url":null,"abstract":"<p><p>BackgroundEnteric fevers (EF) are caused by infections with <i>Salmonella</i> Typhi (STY) or <i>Salmonella</i> Paratyphi (SP) A-C (except the SPB enteric pathovar) and exhibit increasing antimicrobial resistance (AMR). Notification is mandatory in Germany.AimTo describe characteristics and trends of notified EF cases in Germany.MethodsWe analysed German EF notifications 2001-2023 fulfilling the case definition. We calculated numbers of imported EF cases per 100,000 air travellers by country of exposure 2012-2023.ResultsIn 2001-2023, 2,670 confirmed EF cases were notified: 56% (1,498/2,670) STY, 44% (1,172/2,670) SP, with seasonal peaks in April-May and August-September. Aside from years with COVID-19-related travel restrictions, STY notifications were stable, while SP notifications decreased. Median age of EF cases was 26 years (range: 0-93) and 55% (1,458/2,663) were male. Of cases with information, 93% (2,491/2,670) had fever, 71% (1,906/2,670) diarrhoea, 78% (2,033/2,607) were hospitalised (STY: 85% (1,234/1,459) vs SP: 70% (799/1,148), p < 0.001) and four died (two STY, one SPA, one SPB). Of STY cases, 7% (88/1,221) reported vaccination. Overall, 86% (2,251/2,613) of cases acquired EF abroad, most commonly in India, Pakistan and Türkiye. Ciprofloxacin resistance was reported for 50/59 STY and 16/18 SPA cases and cefotaxime resistance for 10/57 STY cases (exposure: Pakistan (9/10), India (1/10)) with information since 2017. We also report outbreaks and incidence among travellers.ConclusionsMost cases were imported and had high hospitalisation rates and AMR. Typhoid vaccination was underutilised, highlighting that additional ways to reach at-risk travellers with information and vaccination offers are needed.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 14","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergence of <i>Salmonella enterica</i> carrying <i>bla</i> _OXA-181 carbapenemase gene, Italy, 2021 to 2024.","authors":"Luca Bolzoni, Erika Scaltriti, Chiara Bracchi, Sara Angelone, Ilaria Menozzi, Roberta Taddei, Patricia Alba, Virginia Carfora, Elena Lavinia Diaconu, Marina Morganti, Alessandra Dodi, Melissa Berni, Laura Manni, Massimiliano Vinci, Martina Tambassi, Laura Mazzera, Irene Venturelli, Simone Ambretti, Antonio Battisti, Stefano Pongolini","doi":"10.2807/1560-7917.ES.2025.30.13.2500175","DOIUrl":"10.2807/1560-7917.ES.2025.30.13.2500175","url":null,"abstract":"<p><p>Between 2021 and 2024, we detected carbapenemase gene <i>blaOXA-181</i> in 16 of 11,398 <i>Salmonella enterica</i> (SE) isolates: 10 SE 1,4,[5],12:i:-, three Bovismorbificans, two London and one Rissen from pigs, humans, pork meat and wild roe deer. The gene was first detected in pig isolates, later in humans, suggesting zoonotic transmission. Phylogenetic analysis indicated that horizontal transfer, mainly through plasmids, contributed to the spread. These findings highlight a possible emerging public health threat and the importance of One Health surveillance.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 13","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11969965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}