Eurosurveillance最新文献

{"title":"Cluster of imported cutaneous leishmaniasis due to <i>Leishmania major</i> among travellers returning from central Tunisia, France, October 2025 to May 2026.","authors":"Morgane Andreoletti, Emilie Guemas, Eléna Charpentier, Judith Fillaux, Alexis Valentin, Pamela Chauvin, Antoine Berry, Xavier Iriart","doi":"10.2807/1560-7917.ES.2026.31.32.2600605","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2026.31.32.2600605","url":null,"abstract":"<p><p>Between October 2025 and May 2026, 28 patients with cutaneous leishmaniasis caused by <i>Leishmania major</i> were identified at Toulouse University Hospital, France, contrasting with fewer than three cases diagnosed annually in 2019-2024. Epidemiological investigations linked 24 cases to recent travel to Tunisia, with 19 reporting exposure in the governorate of Sidi Bouzid, endemic for zoonotic cutaneous leishmaniasis. These findings suggest increased transmission in central Tunisia and reinforce the need for surveillance of imported leishmaniasis in Europe.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 32","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13476725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between heavy rainfall and flooding events and infectious diseases in Europe: a rapid review, 2018 to 2025.","authors":"Nina Rise, Aura Georgina Aguirre-Beltran, Anna K Fotakis, Anne Christine Mariager Breschel, Katja Nyholm Andersen, Steen Ethelberg, Giorgia Solda, Agoritsa Baka, Favelle Lamb, Pikka Jokelainen, Jonathan Suk","doi":"10.2807/1560-7917.ES.2026.31.31.2500902","DOIUrl":"10.2807/1560-7917.ES.2026.31.31.2500902","url":null,"abstract":"<p><p>BACKGROUNDBecause of climate change, the frequency of extreme weather events, including heavy rainfall and flooding, is increasing in Europe. It is important to understand how such events affect infectious disease incidence to inform preparedness and response activities.AIMWe aimed to gather evidence of associations between heavy rainfall and flooding and infectious disease incidence in humans in Europe, as well as report preparedness and response measures.METHODSIn this rapid review, PubMed, Embase and the Cochrane Library were searched using a combination of keywords relevant to infectious diseases as well as to heavy rainfall and flooding to identify published literature and preprints. Articles published between 1 January 2018 and 15 June 2025 were eligible for inclusion.RESULTSFrom 897 records identified, 14 articles were included in the review. In particular, outbreaks of campylobacteriosis and cases of leptospirosis were reported following heavy rainfall and flooding events in Europe. Public health communication on awareness and hygienic practices was among the most commonly reported preparedness and response measure, while structural measures such as sanitary infrastructure and One Health surveillance systems were suggested.CONCLUSIONWhile heavy rainfall and flooding have been associated with outbreaks of infectious diseases in different parts of Europe, relatively few studies investigating these associations were identified in Europe despite wide search criteria, highlighting the need for further research to strengthen European preparedness and response measures.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 31","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13451863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148683900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimating the impact of doxycycline post-exposure prophylaxis on antibiotic consumption among men who have sex with men using PrEP in the EU/EEA.","authors":"Disa Hansson, Anastasia Pharris, Axel Jeremias Schmidt, Kai J Jonas, Ulrich Marcus, Diamantis Plachouras, Liselotte Diaz Högberg, Otilia Mårdh, Jose Canevari","doi":"10.2807/1560-7917.ES.2026.31.31.2500913","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2026.31.31.2500913","url":null,"abstract":"<p><p>BACKGROUNDDoxycycline post-exposure prophylaxis (doxy-PEP) has been shown to reduce the incidence of chlamydia and syphilis among men who have sex with men (MSM) at high risk of sexually transmitted infections (STIs). However, doxy-PEP adds antibiotic exposure and may select for tetracycline resistance in both target and bystander bacteria, raising concerns about antimicrobial resistance (AMR). Quantifying additional antibiotic consumption from doxy-PEP is important for assessing its potential AMR impact at population level.AIMWe estimated the potential increase in doxycycline consumption attributable to doxy-PEP among MSM using HIV pre-exposure prophylaxis (PrEP) in the European Union and European Economic Area (EU/EEA) and compared it with overall doxycycline and tetracycline-class consumption.METHODSWe used Monte Carlo simulation to estimate annual doxycycline use from doxy-PEP among MSM using PrEP. We estimated population size from the 2024 European MSM Internet Survey and derived doxy-PEP uptake and prescribing frequency from expert elicitation. Estimated consumption in defined daily doses (DDD) per year was compared with tetracycline-class and doxycycline antibiotic use reported by the European Surveillance of Antimicrobial Consumption Network.RESULTSDoxy-PEP among MSM using PrEP in the EU/EEA could result in an estimated 4.4 million DDDs of doxycycline annually (95% credible interval (CrI): 0.5-18.1 million), corresponding to a 1.9% increase (95% CrI: 0.2-7.7) relative to 2023 doxycycline consumption.CONCLUSIONThe estimated Doxy-PEP use constitutes a non-negligible share of total doxycycline consumption in the EU/EEA. Monitoring doxy-PEP uptake and AMR indicators will be essential as more countries consider integrating this intervention into STI prevention strategies.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 31","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148683888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of minimum inhibitory concentrations of azithromycin, ceftriaxone and ciprofloxacin for <i>Neisseria gonorrhoeae</i> from antimicrobial resistance sentinel surveillance, Germany, 2014 to 2023.","authors":"Lena Böff, Kathleen Klaper, Achim Dörre, Annemarie Pantke, Susanne Buder, Sandra Dudareva, Viviane Bremer, Dagmar Heuer, Klaus Jansen, Regina Selb","doi":"10.2807/1560-7917.ES.2026.31.34.2500803","DOIUrl":"10.2807/1560-7917.ES.2026.31.34.2500803","url":null,"abstract":"<p><p>BACKGROUND<i>Neisseria gonorrhoeae</i> (NG), the pathogen causing the sexually transmitted infection (STI) gonorrhoea, shows increasing antimicrobial resistance threatening recommended treatments.AIMWe examined temporal trends in antibiotic susceptibility of NG isolates in Germany and possible shifts in sexual networks.METHODSWe analysed annual data from the German antimicrobial resistance sentinel surveillance programme Go-Surv-AMR (2014-2023). Isolates were tested by E-test for phenotypic susceptibility to azithromycin (AZM), ceftriaxone (CRO) and ciprofloxacin (CIP) to determine minimum inhibitory concentrations (MIC). We described patient demographics and calculated MIC metrics by year, sex, age group and specimen type. We assessed differences in yearly MIC distributions using Kolmogorov-Smirnov tests and analysed temporal trends by fitting beta distributions to log-transformed MIC by antibiotic and epidemiological group.RESULTSWe collected 5,421 NG isolates from across Germany, primarily from males (n = 4,704) and from urethral specimens (n = 4,060). From 2016 to 2023, median AZM MIC nearly quadrupled in female and male isolates (0.12-0.45 mg/L). Median CRO MIC remained low overall (≤ 0.009 mg/L) but increased significantly in males in 2022-2023, especially in extragenital/screening isolates. Median CIP MIC increased (0.003-0.0057 mg/L), most pronounced in male extragenital/screening isolates.CONCLUSIONAcross the examined decade, NG showed subtle increases in MIC in extragenital/screening isolates from males, possibly reflecting decreasing antibiotic susceptibility in groups that regularly undergo STI screening. Rising AZM MIC suggests early spread of resistant strains. This highlights the need for continued surveillance, consistent susceptibility testing, targeted education for vulnerable groups, promotion of condom use, and potential vaccination.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 34","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13525358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-country study on the impact of a revised consensus definition of late HIV diagnosis, Europe, 2022 to 2023.","authors":"Peter D Kirwan, Annemarie R Stengaard, Johanna Brännström, Dominique Van Beckhoven, Ard van Sighem, Eline Lm Op de Coul, Barbara Gunsenheimer-Bartmeyer, Uwe Koppe, Helena Cortes-Martins, Vítor Cabral Veríssimo, Marek Malý, Maria Wessman, Chrysa Tsiara, Georgios Ferentinos, Barbara Suligoi, Vincenza Regine, Lucia Pugliese, Sophie Grabar, Ann K Sullivan, Juliana Reyes-Urueña, Anastasia Pharris, Giorgi Kuchukhidze, Ole Kirk, Sara Croxford, Dorthe Raben","doi":"10.2807/1560-7917.ES.2026.31.32.2500921","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2026.31.32.2500921","url":null,"abstract":"<p><p>BACKGROUNDWith improvements in test sensitivity and testing frequency, more people in Europe are diagnosed during the HIV acute/seroconversion phase, when their CD4+ T-cell count can be temporarily low.AIMWe piloted a revised definition of late HIV diagnosis for surveillance which considers laboratory markers, evidence of HIV test negativity in the past year and clinical evidence of recent HIV acquisition, to better distinguish between people diagnosed late and those diagnosed during the acute/seroconversion phase.METHODSWe collected pseudonymised HIV diagnosis records for 2022 and 2023 from nine European countries (Belgium, Czechia, Denmark, Germany, Greece, Italy, the Netherlands, Portugal and Sweden). We applied the revised definition to reclassify those with evidence of recently acquired HIV as 'not late' and calculated the corresponding correction factor by country and demographic group. Individuals with a previous diagnosis were excluded from the analysis.RESULTSAmong 10,220 individuals with a CD4+ T-cell count at diagnosis, 56% (5,689/10,220) had a CD4+ T-cell count < 350 cells/µL or an AIDS-defining event at diagnosis. Applying the revised definition reduced the late diagnosis proportion from 56% to 50%, a correction factor of 9% (535/5,689). The correction factor ranged between 3% and 25% across countries and was higher for younger ages and for gay, bisexual and other men who have sex with men, compared with other groups.CONCLUSIONSWithout reclassification, late HIV diagnosis proportions are overestimated. We provide recommendations and validity considerations for countries intending to use the revised definition.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 32","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13476726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transient Andes orthohantavirus RNA detection in an asymptomatic healthcare worker following indirect exposure during hospital care of an imported case, the Netherlands, 2026.","authors":"Alma Tostmann, Annelies Brilman, Loek Smits, Bram Huizer, Chantal Reusken, Margreet Te Wierik, Helma Ruijs, Corine Geurts van Kessel, Marloes Mattijssen, Manon Tingen-Wieland, Olga Coenen-Bouwman, Matthew McCall, Esmée Ruizendaal, Ingrid van Schalen, Karin Ellen Veldkamp, Rosa van Mansfeld, Annemiek van der Eijk, Heiman Fl Wertheim, Chantal P Rovers","doi":"10.2807/1560-7917.ES.2026.31.31.2600580","DOIUrl":"10.2807/1560-7917.ES.2026.31.31.2600580","url":null,"abstract":"<p><p>Following an outbreak of Andes hantavirus (ANDV) infections on a cruise ship in May 2026, a healthcare worker not directly involved in caring for an imported ANDV case in the Netherlands had a single low-positive ANDV PCR result. The healthcare worker remained asymptomatic, showed no seroconversion, and all subsequent samples tested negative. We describe a retrospective investigation, including detailed reconstruction of potential transmission routes. Our finding may indicate that asymptomatic ANDV infections with low-level viraemia can occur after indirect exposure.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 31","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13451862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148683898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor: Autochthonous transmission patterns of dengue virus serotype 2 in Italy: evidence from outbreaks in 2024.","authors":"Maíra Aguiar, Giulio Pisaneschi, Piero Manfredi, Alberto Landi, Nico Stollenwerk","doi":"10.2807/1560-7917.ES.2026.31.34.2600706","DOIUrl":"10.2807/1560-7917.ES.2026.31.34.2600706","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 34","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13525355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaccine safety surveillance during an mpox outbreak, Germany, June 2022 to February 2024.","authors":"Doris Oberle, Alexandra Hofmann, Klaus Jansen, Uwe Koppe, Raskit Lachmann, Renz Streit","doi":"10.2807/1560-7917.ES.2026.31.30.2500843","DOIUrl":"10.2807/1560-7917.ES.2026.31.30.2500843","url":null,"abstract":"<p><p>BACKGROUNDIn May 2022, first cases of mpox clade IIb were detected in Germany, and MVA-BN vaccine was available from June 2022 onwards. Vaccination has been recommended by the Standing Committee on Vaccination (STIKO) since June 2022 to contain monkeypox virus infection and prevent disease.AIMOur primary aim was to evaluate the safety of the mpox vaccine Jynneos (modified Vaccinia Ankara, Bavaria-Nordic, MVA-BN) after the rollout of the vaccination campaign in Germany from June 2022 to February 2024; a secondary aim was to describe mpox cases and vaccinations.METHODSTo identify cases and persons with adverse events following immunisation (AEFIs), we used existing surveillance systems. A voluntary system was implemented in June 2022 to monitor mpox vaccination. We performed a descriptive analysis of cases, vaccinations, individual case safety reports (ICSRs) and AEFIs.RESULTSUntil 29 February 2024, 3,807 mpox cases were notified (data retrieved July 2024). According to the voluntary mpox vaccination monitoring, a total of 78,739 mpox vaccine doses of Jynneos were administered. A search of the national AEFI database identified 32 ICSRs, of which seven were serious. A total of 87 AEFIs were reported, most of which were local or systemic reactions that are generally associated with vaccination. The overall adverse event reporting rate adjusted for missing information on vaccine utilisation in one of 16 federal states was 98.7 adverse events per 100,000 doses.CONCLUSIONThe safety profile of the MVA-BN vaccine was in line with the summary of product characteristics. No new safety signals were identified.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 30","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13428197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148629827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author's correction for Euro Surveill. 2026;31(25).","authors":"","doi":"10.2807/1560-7917.ES.2026.31.26.260702c","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2026.31.26.260702c","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 26","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National automated surveillance of hospital onset bacteraemia and fungaemia using data from the national antimicrobial resistance surveillance system: a retrospective exploratory evaluation, the Netherlands, 2018 to 2023.","authors":"Manon Brekelmans, Tjallie van der Kooi, Annelot F Schoffelen, Rony E Zoetigheid, Maaike Sm van Mourik, Sabine de Greeff, Stephanie van Rooden","doi":"10.2807/1560-7917.ES.2026.31.28.2500881","DOIUrl":"10.2807/1560-7917.ES.2026.31.28.2500881","url":null,"abstract":"<p><p>BACKGROUNDHospital-onset bacteraemia and fungaemia (HOB) is a new target for automated surveillance of healthcare-associated infections.AIMWe aimed to evaluate (i) whether data from a national laboratory-based antimicrobial resistance (AMR) surveillance system (ISIS-AR) are a suitable source for fully automated HOB surveillance and (ii) whether the derived HOB rates from automated surveillance are a useful measure for national surveillance.METHODSWe applied an algorithm based on a consensus HOB definition to ISIS-AR data from 2018 to 2023. We performed: (i) technical evaluation of the data to determine their suitability for automated HOB surveillance, (ii) outcome validation of automatically identified HOB cases in four hospitals, and (iii) qualitative interviews with stakeholders on the anticipated value of HOB surveillance.RESULTSMost parameters required for HOB identification were present, except for hospital admission dates (≥ 80% available in only 14 hospitals). Outcome validation showed accurate identification of HOBs caused by pathogens (non-commensals), but identification of HOBs caused by common commensals varied between hospitals, reflecting laboratory policy differences. Interviewees emphasised that feedback from national HOB surveillance to hospitals can be valuable for monitoring local trends, as signal for in-depth investigations and benchmarking.CONCLUSIONDutch national automated HOB surveillance based on secondary use of national AMR surveillance data for pathogen-related HOBs is feasible, particularly if recording admission date is improved. Understanding local routine care and diagnostic practices is crucial for the interpretation of results. The main usefulness is expected at hospital level, while its value for national trend monitoring needs further study.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 28","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13379685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}