EurosurveillancePub Date : 2025-10-01DOI: 10.2807/1560-7917.ES.2025.30.39.2500251
Joyce Pijpers, Annika van Roon, Maarten Schipper, Marijn Stok, Susan van den Hof, Ruben van Gaalen, Susan Hahné, Hester de Melker
{"title":"The decrease in childhood vaccination coverage and its sociodemographic determinants, the Netherlands, birth cohorts 2008 to 2020.","authors":"Joyce Pijpers, Annika van Roon, Maarten Schipper, Marijn Stok, Susan van den Hof, Ruben van Gaalen, Susan Hahné, Hester de Melker","doi":"10.2807/1560-7917.ES.2025.30.39.2500251","DOIUrl":"10.2807/1560-7917.ES.2025.30.39.2500251","url":null,"abstract":"<p><p>INTRODUCTIONChildhood vaccination coverage has declined in recent years in many countries, including the Netherlands.AIMTo understand differences in coverage between population subgroups in the Netherlands over time, we studied sociodemographic factors associated with measles-mumps-rubella (MMR) and diphtheria-tetanus-pertussis-poliomyelitis (DTaP-IPV) vaccination.METHODSWe conducted a national retrospective database study including children born between 2008 and 2020. Individual-level data linkage allowed examination of associations of sociodemographic variables with MMR and DTaP-IPV vaccination status at age 2 years. We calculated coverage for each variable, stratified by birth cohort. Multivariable Poisson regression assessed independent associations and changes in coverage over time.RESULTSMMR coverage decreased in all population subgroups (overall 95% in cohort 2008 and 89% in cohort 2020), more substantially in some. In multivariable analysis, children of non-Dutch origin, particularly Moroccan and Turkish origin, showed more pronounced declines (respectively -25% and -12% as children of Dutch origin in cohort 2020). Among children not attending daycare and children living in larger families (≥ 4 children), coverage declined faster than in those attending daycare and living in smaller families (both -12% in cohort 2020). Coverage among children of self-employed mothers and children in the lowest income households was lower than among children of mothers in employment and the highest income households (respectively -8% and -7% in cohort 2020). Trends for DTaP-IPV vaccination were nearly identical.CONCLUSIONChildhood vaccination coverage in the Netherlands declined substantially, with increasing disparities between sociodemographic groups. Vaccination efforts should be prioritised to protect public health equitably.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 39","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Author's response: Peanut butter confirmed as the source of a case of infant botulism in the United Kingdom, 2024.","authors":"Corinne Fl Amar, Rosie J Crane, Shamez Ladhani, Dunstan Rajendram, Vanessa K Wong, Gauri Godbole","doi":"10.2807/1560-7917.ES.2025.30.40.2500757","DOIUrl":"10.2807/1560-7917.ES.2025.30.40.2500757","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 40","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12514438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurosurveillancePub Date : 2025-10-01DOI: 10.2807/1560-7917.ES.2025.30.40.251009a
{"title":"Addendum for Euro Surveill. 2025;30(36).","authors":"","doi":"10.2807/1560-7917.ES.2025.30.40.251009a","DOIUrl":"10.2807/1560-7917.ES.2025.30.40.251009a","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 40","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12514437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurosurveillancePub Date : 2025-10-01DOI: 10.2807/1560-7917.ES.2025.30.40.2500738
Regina Selb, Hana Tlapák, Kathleen Klaper, Susanne Buder, Klaus Jansen, Dagmar Heuer
{"title":"Autochthonous transmission of extensively drug-resistant <i>Neisseria gonorrhoeae</i> in Germany, 2025.","authors":"Regina Selb, Hana Tlapák, Kathleen Klaper, Susanne Buder, Klaus Jansen, Dagmar Heuer","doi":"10.2807/1560-7917.ES.2025.30.40.2500738","DOIUrl":"10.2807/1560-7917.ES.2025.30.40.2500738","url":null,"abstract":"<p><p>We report four confirmed autochthonously transmitted gonorrhoea cases in Germany in 2025, with <i>Neisseria gonorrhoeae</i> isolates exhibiting high-level azithromycin and cefixime resistance. Regarding ceftriaxone, isolates were susceptible for two cases and resistant for two, rendering the later extensively drug-resistant (XDR-NG). Cases, all heterosexual males, were in their late teens to mid-60s. Three isolates were MLST ST18091, with the mosaic <i>penA</i>-60.001 allele and the 23S rRNA A2045G mutation and were related to an XDR-NG detected in the United Kingdom in 2024.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 40","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12514436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurosurveillancePub Date : 2025-10-01DOI: 10.2807/1560-7917.ES.2025.30.39.2500270
Taimoor Hasan, Ewan Wilkinson, Valérie Decraene, Ariadni Kouzeli, Cheryl Gibbons, Vera Chua, Roberto Vivancos, Sam Ghebrehewet
{"title":"Impact of vaccination on pertussis-related hospital admissions in children in Scotland from January 2013 to July 2024: a cohort study.","authors":"Taimoor Hasan, Ewan Wilkinson, Valérie Decraene, Ariadni Kouzeli, Cheryl Gibbons, Vera Chua, Roberto Vivancos, Sam Ghebrehewet","doi":"10.2807/1560-7917.ES.2025.30.39.2500270","DOIUrl":"10.2807/1560-7917.ES.2025.30.39.2500270","url":null,"abstract":"<p><p>BACKGROUNDIn Scotland, the number of pertussis infections recorded in children in 2024 was the highest of any year in the last decade. The protective role of vaccination against severe infection and associated hospitalisations has not been assessed.AIMTo investigate the effect of vaccination and sociodemographic factors on pertussis-related hospitalisations in Scottish children aged under 18 years.METHODSIn a retrospective cohort study, laboratory-confirmed pertussis cases from January 2013 to July 2024 were extracted from the national electronic surveillance system and linked to hospitalisation data from Scottish Morbidity Records and vaccination data from the national immunisations database. The outcome was a pertussis-associated hospitalisation. Multivariable logistic regression was used to calculate odds ratios (OR) for the association between vaccination status and hospitalisation, adjusted for age, sex, ethnicity and deprivation status.RESULTSThere were 3,982 laboratory-confirmed cases of pertussis during the study period. Children fully vaccinated for age had significantly lower odds of hospitalisations than unvaccinated children (adjusted OR (aOR): 0.31; 95% CI: 0.21-0.46). Being partially vaccinated for age did not significantly reduce hospitalisations relative to unvaccinated children (aOR: 0.80; 95% CI: 0.47-1.33). In the univariable analysis, children living in the most deprived areas had significantly more hospitalisations than those in the least deprived areas (OR: 3.90; 95% CI: 2.41-6.56). This association was not significant when adjusted for the effect of vaccination (aOR: 1.47; 95% CI: 0.84-2.66).CONCLUSIONSFully vaccinated children had significantly lower odds of hospitalisation, indicative of less severe disease. This emphasises the importance of fully vaccinating children according to the childhood immunisation schedule.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 39","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurosurveillancePub Date : 2025-10-01DOI: 10.2807/1560-7917.ES.2025.30.39.2500096
Sarah van de Berg, Andreas Beyerlein, Johannes Stephani, Beatrix Bäumler-Merl, Manuela Jäger, Dagmar Königer, Ruprecht Schmidt-Ott
{"title":"Tuberculosis contact investigation: an evaluation of yield and guideline adherence, Upper Bavaria, Germany, 2018 to 2022.","authors":"Sarah van de Berg, Andreas Beyerlein, Johannes Stephani, Beatrix Bäumler-Merl, Manuela Jäger, Dagmar Königer, Ruprecht Schmidt-Ott","doi":"10.2807/1560-7917.ES.2025.30.39.2500096","DOIUrl":"10.2807/1560-7917.ES.2025.30.39.2500096","url":null,"abstract":"<p><p>BACKGROUNDContact investigation of index cases is important for tuberculosis (TB) control in low-incidence countries, yet key performance metrics have not been evaluated in Germany.AIMWe aimed to assess the yield of TB contact investigations, compliance with national guidelines and risk factors for infection among contacts.METHODSWe analysed anonymised data of TB patients and their contacts collected between 2018 and 2022 in Upper Bavaria, Germany. We assessed testing coverage, latent TB infection (LTBI), TB yield, primary prophylaxis and preventive treatment coverage. Risk factors for <i>M. tuberculosis</i> infection (positive tuberculin skin test (TST) / interferon-gamma release assay (IGRA) and/or TB diagnosis) among contacts were identified using multivariable logistic regression and classification tree.RESULTSOf the 2,186 contacts of 174 TB patients, 2,022 (92.5%) had a valid TST/IGRA result and/or a TB diagnosis. Of these, 308 (15.2%) had <i>M. tuberculosis</i> infection, including 10 (0.5%) with TB. Of 241 contacts with LTBI, 66 (28.2%) completed preventive treatment. Among 124 children < 5 years, testing coverage was 75.8%, 16.9% received an immediate chest X-ray and 72.7% primary prophylaxis. Key predictors of infection were born outside Germany (odds ratio (OR) = 2.85; 95% confidence interval (CI): 1.94-4.21) and exposure in community housing (OR = 2.65; 95% CI: 1.65-4.30; reference: exposure at work) or household/family (OR = 2.62; 95% CI: 1.74-4.00).CONCLUSIONWe observed high screening coverage of contacts and yield and risk factors comparable to other low-incidence settings. There is room for improvement regarding preventive treatment and screening of children < 5 years.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 39","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurosurveillancePub Date : 2025-10-01DOI: 10.2807/1560-7917.ES.2025.30.41.2400804
Sophie Raguet, Christophe Ginevra, Ghislaine Descours, Clémence Augustin, Astrid Rebert-Placide, Michel Vernay, Sophie Jarraud, Christine Campèse
{"title":"A community Legionnaires' disease outbreak linked to a collective biomass condensing boiler, France, 2019.","authors":"Sophie Raguet, Christophe Ginevra, Ghislaine Descours, Clémence Augustin, Astrid Rebert-Placide, Michel Vernay, Sophie Jarraud, Christine Campèse","doi":"10.2807/1560-7917.ES.2025.30.41.2400804","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2025.30.41.2400804","url":null,"abstract":"<p><p>Between 1 November and 12 December 2019, a Legionnaires' disease (LD) outbreak occurred in the Strasbourg metropolitan area, France. Epidemiological, environmental and genomic investigations (nested sequence-based typing and whole genome sequencing (WGS)) were undertaken to locate the outbreak source, characterise the causal <i>Legionella</i> strain, and understand its spread. Through a positive urinary antigen test, 28 cases (14 male; 14 female) with 70 years median age (range: 42-88 years) were diagnosed. Two died. For nine cases, typing revealed <i>L. pneumophila</i> serogroup 1 (Lp 1) sequence type (ST) 62 infection. Mapping where cases were during their incubation period pointed to a place south-west of Strasbourg city as the outbreak epicentre. There, in the biomass condensing boiler of a heating plant, high Lp 1 contamination levels (105-106 CFU/L) were discovered. Eight environmental Lp 1 isolates from inside the plant were ST62. Analysing WGS data from these isolates and the nine Lp 1 ST62 clinical isolates, found their sequences clustering with zero to two single nt polymorphisms. Sub-optimal maintenance and warm weather before the boiler started operating may have allowed Lp 1 proliferation within, with boiler fumes subsequently disseminating Lp 1, thereby exposing people. This outbreak highlights potential LD risks arising from innovative energy-saving heat production processes designed to reduce greenhouse gas emissions.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 41","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145307354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurosurveillancePub Date : 2025-10-01DOI: 10.2807/1560-7917.ES.2025.30.39.202510027
{"title":"Job vacancy at the European Centre for Disease Prevention and Control (ECDC).","authors":"","doi":"10.2807/1560-7917.ES.2025.30.39.202510027","DOIUrl":"10.2807/1560-7917.ES.2025.30.39.202510027","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 39","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurosurveillancePub Date : 2025-10-01DOI: 10.2807/1560-7917.ES.2025.30.41.2400719
Nuria Labiod, Mª Paz Sánchez-Seco, Josune Goikoetxea, Nelly Daniela Zurita, Francesca F Norman, Miguel M Martínez, Pedro Alonso Alonso, Araceli Hernández-Betancor, Marco Antonio Sempere-Alcocer, Zaira Moure, Maria Dolores Ocete, Maria Rosario Vicente, Fernando de la Calle-Prieto, Mikel Gallego, Laura Cardeñoso Domingo, Juan Carlos Galán, Daniel Camprubí-Ferrer, Carlos Meilán, Isabel Perez-Hernandez, Itxasne Cabezón, Francisco Javier Hernández, Enrique Bernal, Ana Vázquez
{"title":"Case series of Oropouche fever among travellers returning from Cuba to Spain, 2024.","authors":"Nuria Labiod, Mª Paz Sánchez-Seco, Josune Goikoetxea, Nelly Daniela Zurita, Francesca F Norman, Miguel M Martínez, Pedro Alonso Alonso, Araceli Hernández-Betancor, Marco Antonio Sempere-Alcocer, Zaira Moure, Maria Dolores Ocete, Maria Rosario Vicente, Fernando de la Calle-Prieto, Mikel Gallego, Laura Cardeñoso Domingo, Juan Carlos Galán, Daniel Camprubí-Ferrer, Carlos Meilán, Isabel Perez-Hernandez, Itxasne Cabezón, Francisco Javier Hernández, Enrique Bernal, Ana Vázquez","doi":"10.2807/1560-7917.ES.2025.30.41.2400719","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2025.30.41.2400719","url":null,"abstract":"<p><p>Oropouche fever is a vector-borne disease endemic in Central and South America. Infection with Oropouche virus (OROV) was confirmed in June and July 2024 in 13 patients travelling from Cuba to Spain. These patients presented fever, headache, myalgia and arthralgia, and three patients exhibited a biphasic course, with two developing transient neurological symptoms. Oropouche virus infection was diagnosed using reverse transcription quantitative PCR (RT-qPCR) and neutralisation tests. Viral RNA was detected in specimens from serum, urine, plasma and whole blood; from four urine samples up to 24 days post-symptom onset. Phylogenetic analysis of one OROV strain (OROV SP2024) isolated from one patient, demonstrated it clustered closely with reassortant strains circulating in Brazil and imported cases in Italy. These findings underscore the importance of including OROV in the differential diagnosis of febrile illnesses in returning travellers and demonstrate the diagnostic value of analysing multiple sample types. Enhanced clinical awareness and diagnostic capacity are essential to improve detection and surveillance of OROV among international travellers from affected regions.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 41","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145307356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurosurveillancePub Date : 2025-10-01DOI: 10.2807/1560-7917.ES.2025.30.39.2500026
Sara Farina, Alessandra Maio, Andrea Zaino, Luigi Russo, Walter Ricciardi, Roberto Ieraci, Leonardo Villani
{"title":"A review of childhood rotavirus vaccination policies and a presentation of vaccine coverage trends at national and regional level, Italy, 2016 to 2023.","authors":"Sara Farina, Alessandra Maio, Andrea Zaino, Luigi Russo, Walter Ricciardi, Roberto Ieraci, Leonardo Villani","doi":"10.2807/1560-7917.ES.2025.30.39.2500026","DOIUrl":"10.2807/1560-7917.ES.2025.30.39.2500026","url":null,"abstract":"<p><p>BACKGROUNDRotavirus is a main gastroenteritis cause in children ≤ 5 years old. In 2017, when few Italian regions had rotavirus vaccination programmes, rotavirus vaccines were included in the National Plan for Preventive Vaccination (PNPV). Although all Italian regions follow the PNPV, they each decide how to implement it, contributing to rotavirus vaccination coverage differences across the country.AIMThe objective was to assess rotavirus vaccination national/regional policies in Italy and, between 2016 and 2023, vaccination coverage trends at national and regional level.METHODSScientific and grey literature was systematically reviewed for reports on Italian national/regional policies or programmes concerning rotavirus vaccination. Their key features and strategies to increase vaccination coverage were recorded. Vaccination coverage data originating from the Ministry of Health, were analysed descriptively, or with linear regression, for national and regional trends.RESULTSAmong 418 policy/programme reports identified, 25 were included. Between 2013 and 2015, Sicilia, Calabria and Puglia had already initiated universal vaccination programmes. The PNPV 2017-19 standardised regions' offer of rotavirus vaccination. Between 2016 and 2023, vaccination coverage in Italy significantly increased (p = 0.0005) from 10.5% to 70.76%, with a 140% rise in 2019-20. Regional coverage disparities existed. Throughout 2016-23, most central Italian regions had annual coverages below national values. Bolzano annual coverage was consistently < 50%, while in Veneto, coverage reached 85.10% in 2021. In 2023, five regions had > 80% coverage.CONCLUSIONSWhile rotavirus vaccination coverage improved in Italy in 2016-23, regional disparities persist. Addressing these requires overcoming logistical and societal challenges, as well as harmonised policies.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 39","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}