Eurosurveillance最新文献

A multi-country outbreak of Salmonella Blockley associated with tomato consumption, July to October 2024. 2024年7月至10月，与食用番茄有关的布洛克利沙门氏菌在多国暴发。

IF 8.3 2区医学

Eurosurveillance Pub Date : 2026-10-01 DOI: 10.2807/1560-7917.ES.2026.31.40.2500862

Ann Hoban, Lucy Findlater, Ellen Heinsbroek, Juliette Cavaye, Anais Painset, Clare Maguire, Katie Thorley, Andrew Nelson, Lynda Browning, Derek Brown, Frieda Jorgensen, Jonathan Lighthill, Sandra Simon, Jean-Marc Collard, Nathalie Jourdan-Da Silva, Heather Charles, Jordan Putney, Thai-An Nguyen, Lesley Larkin, Gauri Godbole, Marie Chattaway

{"title":"A multi-country outbreak of Salmonella Blockley associated with tomato consumption, July to October 2024.","authors":"Ann Hoban, Lucy Findlater, Ellen Heinsbroek, Juliette Cavaye, Anais Painset, Clare Maguire, Katie Thorley, Andrew Nelson, Lynda Browning, Derek Brown, Frieda Jorgensen, Jonathan Lighthill, Sandra Simon, Jean-Marc Collard, Nathalie Jourdan-Da Silva, Heather Charles, Jordan Putney, Thai-An Nguyen, Lesley Larkin, Gauri Godbole, Marie Chattaway","doi":"10.2807/1560-7917.ES.2026.31.40.2500862","DOIUrl":"10.2807/1560-7917.ES.2026.31.40.2500862","url":null,"abstract":"Between July and October 2024, 216 cases with genetically related Salmonella Blockley sequence type 52 were identified in France (n = 56), Germany (n = 30), the United Kingdom (UK) (n = 129) and the United States (US) (n = 1). Case interviews in the UK identified tomatoes as a possible vehicle of infection. A rapid case-control study with 29 cases and 87 controls was conducted to investigate this hypothesis, using pre-existing control data. Multivariable, Firth penalised logistic regression was used to explore associations between illness, food exposures and retailers. Consumption of tomatoes and shopping at Retailer A (adjusted odds ratio (aOR) = 10.75; 95% confidence interval (CI): 1.52-103.16) was associated with being a case. Salmonella spp. was not detected in any of the 312 tomato samples tested by a standard culture method, but a low concentration of Salmonella DNA was detected in two enriched broths by PCR. These detections could not be confirmed by culture. Evidence derived from epidemiological, microbiological and food chain investigations in the UK identified imported tomatoes from Morocco as the most likely vehicle of infection.","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 40","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Timely evidence generation in epidemic response: lessons from an attempted analytical epidemiological investigation during an mpox outbreak, Ireland, 2022. 流行病应对中及时产生证据：从麻疹暴发期间试图进行的分析性流行病学调查中吸取的教训，爱尔兰，2022年。

IF 8.3 2区医学

Eurosurveillance Pub Date : 2026-10-01 DOI: 10.2807/1560-7917.ES.2026.31.39.2600170

Charlotte Salgaard Nielsen, Eve Robinson, Patricia Garvey, Kate O'Donnell, Noel McCarthy, Randal Parlour, Fiona Lyons, Derval Igoe

{"title":"Timely evidence generation in epidemic response: lessons from an attempted analytical epidemiological investigation during an mpox outbreak, Ireland, 2022.","authors":"Charlotte Salgaard Nielsen, Eve Robinson, Patricia Garvey, Kate O'Donnell, Noel McCarthy, Randal Parlour, Fiona Lyons, Derval Igoe","doi":"10.2807/1560-7917.ES.2026.31.39.2600170","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2026.31.39.2600170","url":null,"abstract":"The emergence of mpox cases in Ireland in May 2022 triggered an urgent public health response, including an attempted analytical epidemiological investigation aimed at informing vaccination strategies and risk communication, particularly among gay, bisexual and other men who have sex with men. At the time of implementation, case numbers had declined to an extent that limited recruitment, resulting in early suspension of data collection. We present a structured reflection of the investigation, drawing on a lessons learnt review and the experiences of those involved, to offer actionable recommendations to strengthen evidence generation in future outbreak preparedness and response efforts. Key lessons include the critical importance of stakeholder engagement, clear governance and legal frameworks, and the need for enhanced procedural preparedness and pre-established surge capacity arrangements to enable rapid analytical investigations during health emergencies. These insights align closely with Ireland's National Health Protection Strategy and the extended mandate of the European Centre for Disease Prevention and Control. Beyond existing international frameworks for outbreak preparedness, this reflection highlights the practical implementation barriers that must be addressed to enable timely and coordinated epidemiological investigations across Europe.","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 39","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High levels of domestic transmission and drug resistance -analysis of national surveillance data for shigellosis, the Netherlands, 2018 to 2024. 国内传播和耐药水平高——2018年至2024年荷兰志贺氏菌病国家监测数据分析

IF 8.3 2区医学

Eurosurveillance Pub Date : 2026-10-01 DOI: 10.2807/1560-7917.ES.2026.31.41.2600075

Boas van der Putten, Hendrik Sauskojus, Anouk Meijs, Daan Notermans, Maren Lanzl, Eelco Franz, Maaike van den Beld, Roan Pijnacker

{"title":"High levels of domestic transmission and drug resistance -analysis of national surveillance data for shigellosis, the Netherlands, 2018 to 2024.","authors":"Boas van der Putten, Hendrik Sauskojus, Anouk Meijs, Daan Notermans, Maren Lanzl, Eelco Franz, Maaike van den Beld, Roan Pijnacker","doi":"10.2807/1560-7917.ES.2026.31.41.2600075","DOIUrl":"10.2807/1560-7917.ES.2026.31.41.2600075","url":null,"abstract":"BACKGROUNDAntimicrobial resistance (AMR) among Shigella species is increasing, which is concerning. Strengthening surveillance is key to obtaining accurate, timely and actionable data on shigellosis.AIMWe aimed to describe Dutch national shigellosis surveillance data from 2018 to 2024, spanning the implementation of national genomic surveillance in 2022.METHODSWe described notified shigellosis cases and used logistic regression models to analyse associations between shigellosis and age, sex, year of infection, province, MSM (men who have sex with men) association, travel status, severity of disease and Shigella species.RESULTSIn 2018-2024, 3,020 shigellosis cases were notified. Incidence of shigellosis decreased during the COVID-19 pandemic years 2020-2021 but returned to pre-pandemic incidence in 2023 and 2024. Most cases were males (n = 1,887; 62.5%). Of the 1,731 cases with available data, 732 (42.3%) reported recent contact with MSM, representing 24.2% of all shigellosis cases. The proportion of extensive drug resistant (XDR) isolates increased from 2018 (1/58) to 2023 (24/109; 22.0%) (p < 0.001). Cases were more likely to be part of a cluster if they reported a recent MSM contact (p < 0.001) or harboured an XDR isolate (p < 0.001). Cases with recent MSM contact were more likely to harbour an XDR strain (p < 0.001).CONCLUSIONImplementation of genomic surveillance facilitated detection of clusters, provided more timely data on AMR and allowed for more detailed analyses of risk factors for Shigella transmission. Continued intervention efforts promoting hygiene and raising awareness on shigellosis and AMR are important to curb the increase of XDR shigellosis.","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 41","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends and risk factors associated with hepatitis A severity and mortality in French hospitals: a national population-based study, 2013 to 2024. 法国医院中与甲型肝炎严重程度和死亡率相关的趋势和危险因素：2013年至2024年一项基于全国人群的研究

IF 8.3 2区医学

Eurosurveillance Pub Date : 2026-10-01 DOI: 10.2807/1560-7917.ES.2026.31.39.2500858

Anne-Marie Roque-Afonso, Charlotte Mouliade, Lucia Parlati, Nathalie Goutté, Julie Figoni, Samir Bouam, Philippe Sogni, Vincent Mallet

{"title":"Trends and risk factors associated with hepatitis A severity and mortality in French hospitals: a national population-based study, 2013 to 2024.","authors":"Anne-Marie Roque-Afonso, Charlotte Mouliade, Lucia Parlati, Nathalie Goutté, Julie Figoni, Samir Bouam, Philippe Sogni, Vincent Mallet","doi":"10.2807/1560-7917.ES.2026.31.39.2500858","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2026.31.39.2500858","url":null,"abstract":"BACKGROUNDAs hepatitis A (HA) incidence declines in Europe and HA virus infections occur later in life, severe disease frequency may increase.AIMAmong patients hospitalised for HA in France during 2013-2024, we investigated disease severity and mortality associated-risk factors and temporal trends.METHODSInternational Classification of Diseases, 10th Revision codes B150 or B159 as primary discharge diagnosis enabled identifying HA cases from the National Discharge Data Set. Risk factors for severity (hepatic and/or extrahepatic organ failure within 12 weeks post-admission) and mortality were assessed using adjusted odds ratios in original and propensity-matched samples. Trends were determined across five periods covering an HA epidemic in 2017 and the COVID-19 pandemic, with 2013-2016 as reference.RESULTSAmong 7,923 cases (60.6% male, 39.4% female; median age: 30 years), 28.7% (n = 2,277) developed severe HA, and 1.30% (n = 103) died. Severe HA was associated with older age (+ 15% per decade over 30 years, p < 0.001), male sex (+ 38%, p < 0.001), smoking (+ 23%, p = 0.031), risk factors for chronic liver disease (+ 29%, p = 0.041), and cirrhosis (+ 40%, p = 0.054). Mortality was associated with cirrhosis (2.90-fold increase, p = 0.004), Charlson Comorbidity Index (CCI) ≥ 3 (12.3-fold increase, p < 0.001), and modestly with age (+ 24%, p = 0.005), reaching + 90% (p < 0.001) in models without CCI, indicating a considerable comorbidity effect. From 2013-2016, severe HA and HA-related death risks respectively increased 57% (p < 0.001) and 1.96-fold (p = 0.016) in 2021-2024.CONCLUSIONSSevere HA frequency and mortality increased in French hospitals since 2013. Age and male sex were associated with severe disease, and high CCI with mortality. A more extensive, or even universal, vaccination policy could be considered.","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 39","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in age composition and epidemiology of candidaemia, Iceland, 2012 to 2023. 冰岛2012 - 2023年念珠菌病年龄构成及流行病学变化

IF 8.3 2区医学

Eurosurveillance Pub Date : 2026-10-01 DOI: 10.2807/1560-7917.ES.2026.31.40.2600120

Lena Ros Asmundsdottir, Johanna Gudrun Bergthorsdottir, Andri Oddur Steinarsson, Magnus Gottfredsson

{"title":"Changes in age composition and epidemiology of candidaemia, Iceland, 2012 to 2023.","authors":"Lena Ros Asmundsdottir, Johanna Gudrun Bergthorsdottir, Andri Oddur Steinarsson, Magnus Gottfredsson","doi":"10.2807/1560-7917.ES.2026.31.40.2600120","DOIUrl":"10.2807/1560-7917.ES.2026.31.40.2600120","url":null,"abstract":"BACKGROUNDCandidaemia places a substantial burden on healthcare systems. Long-term, population-based studies of candidaemia rates with appropriate adjustments for changes in age composition are lacking.AIMWe aimed to determine trends in candidaemia incidence rates, species distribution, antifungal susceptibility, and concurrent antifungal use in Iceland between 2012 and 2023, as well as long-term (2000-2023) trends in age-standardised incidence rates (ASRs).METHODSWe analysed patient data with blood cultures positive for Candida species, or yeasts previously assigned to the genus Candida. We calculated ASRs, standardised to the 2023 Icelandic population, and performed susceptibility testing on all available isolates.RESULTSOverall, we identified 207 candidaemia episodes in 193 patients. The average ASR was 5.2 cases per 100,000 population. The ASR increased significantly from 2012 to 2023 (incidence rate ratio (IRR) = 1.07; p = 0.001), mainly driven by increased rates among males (IRR = 1.10; p = 0.001). From 2000 to 2023, the ASR remained stable (average 5.8/100,000; IRR = 1.00). The ASR was higher among males, both during 2012-2023 (p = 0.014) and long-term (2000-2023, p = 0.001). Age-specific incidence rate was highest among > 80-year-old males (44.0/100,000). Candida albicans was the most frequent species (41.0%), followed by Nakaseomyces glabratus (27.2%) and Candida tropicalis (11.1%). Fluconazole susceptibility remained high (C. albicans 99%, C. tropicalis 75%, Candida parapsilosis 100%), and echinocandin resistance was rare (1.9%).CONCLUSIONDespite an apparent increase from 2012 to 2023, candidaemia incidence in Iceland has remained stable in a long-term (24-year) perspective, when appropriate adjustments are made for the ageing population. Concurrently, the epidemiology has shifted towards non-albicans Candida infections.","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 40","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the impact of the COVID-19 pandemic on routine childhood vaccination uptake, the Netherlands, 2016 to 2025. 评估2016 - 2025年荷兰COVID-19大流行对儿童常规疫苗接种率的影响

IF 8.3 2区医学

Eurosurveillance Pub Date : 2026-10-01 DOI: 10.2807/1560-7917.ES.2026.31.40.2600159

Joyce Pijpers, Manon Haverkate, Ruben van Gaalen, Susan Hahné, Hester de Melker, Susan van den Hof

{"title":"Assessing the impact of the COVID-19 pandemic on routine childhood vaccination uptake, the Netherlands, 2016 to 2025.","authors":"Joyce Pijpers, Manon Haverkate, Ruben van Gaalen, Susan Hahné, Hester de Melker, Susan van den Hof","doi":"10.2807/1560-7917.ES.2026.31.40.2600159","DOIUrl":"10.2807/1560-7917.ES.2026.31.40.2600159","url":null,"abstract":"BACKGROUNDThe Netherlands has experienced a decline in routine childhood vaccination uptake during and after the COVID-19 pandemic, with emerging evidence of reduced parental vaccine confidence.AIMTo evaluate the immediate and long-term impact of the COVID-19 pandemic on first-dose diphtheria-tetanus-pertussis-poliomyelitis (DTaP-IPV) vaccination uptake.METHODSWe conducted a retrospective nationwide cohort study including all children born in the Netherlands in 2016-2024. First-dose DTaP-IPV vaccination status by age 6 months was obtained from the national immunisation register. National trends in vaccination uptake across pre-pandemic, pandemic and post-pandemic periods were assessed using interrupted time series analyses (ITS). To further assess the independent effects of the pandemic, matched-sibling analysis compared vaccination uptake within families before, during and after the pandemic.RESULTSITS showed significant immediate decreases in vaccination uptake both at the start and end of the pandemic, accompanied by a continuing downward trend during the pandemic (OR: 0.984; 95% CI: 0.981-0.986) that further declined after its end (OR: 0.995; 95% CI: 0.993-0.998). In the matched-sibling analysis, children eligible during and after the pandemic had lower odds of being vaccinated (pandemic: OR: 0.66; 95% CI: 0.55-0.80; post-pandemic: OR: 0.20; 95% CI: 0.17-0.25) compared with their pre-pandemic siblings. Also, later birth order was associated with lower odds compared with first-born siblings (second-born: OR: 0.42; 95% CI: 0.37-0.48).CONCLUSIONSBoth analyses indicate a negative impact of the COVID-19 pandemic on childhood vaccination uptake, which may reflect lingering pandemic effects and/or new post-pandemic factors, highlighting the need for further research into the drivers of vaccination uptake changes in the post-pandemic era.","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 40","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding vaccination against human papillomavirus (HPV): knowledge and perceptions among parents or guardians and healthcare workers, Germany, 2023. 了解人乳头瘤病毒（HPV）疫苗接种：父母或监护人和卫生保健工作者的知识和观念，德国，2023

IF 8.3 2区医学

Eurosurveillance Pub Date : 2026-10-01 DOI: 10.2807/1560-7917.ES.2026.31.41.2500910

Nora Katharina Schmid-Küpke, Elisa Wulkotte, Yvonne Bichel, Heike Kramer, Johannes Lachmann, Andrea Mais, Philipp Schmid, Jule Marie Schmitz, Ole Wichmann, Anja Takla

{"title":"Understanding vaccination against human papillomavirus (HPV): knowledge and perceptions among parents or guardians and healthcare workers, Germany, 2023.","authors":"Nora Katharina Schmid-Küpke, Elisa Wulkotte, Yvonne Bichel, Heike Kramer, Johannes Lachmann, Andrea Mais, Philipp Schmid, Jule Marie Schmitz, Ole Wichmann, Anja Takla","doi":"10.2807/1560-7917.ES.2026.31.41.2500910","DOIUrl":"10.2807/1560-7917.ES.2026.31.41.2500910","url":null,"abstract":"BACKGROUNDVaccination against human papillomavirus (HPV) is effective against certain types of cancer. Despite longstanding vaccination recommendation, HPV vaccination has the lowest coverage among all recommended vaccines for children and adolescents in Germany, with notable differences between sexes.AIMWe aimed to investigate attitudes towards vaccination against HPV and HPV-related knowledge among parents or guardians and healthcare workers (HCW) in Germany, alongside vaccination intentions and determinants in parents/guardians and vaccination counselling in HCWs.METHODSIn autumn 2023, we conducted telephone interviews with 1,508 parents/guardians of children and adolescents aged 9-14 years and 503 HCWs from paediatric practices. We used weighting and analysed the responses with t test and ANOVA.RESULTSOverall, 34.5% children of the interviewed parents/guardians were already vaccinated against HPV, while 24.8% of parents/guardians reported a high intention, 5.6% opposed to vaccination and 35.2% were considered vaccine hesitant. Parents/guardians and HCWs considered vaccination of females more important than of males (p < 0.001). Parents/guardians exhibited knowledge gaps, for example, by overestimating alternative measures (e.g. condom use) for cancer prevention; HCWs expressed uncertainties about the risk of HPV infection. Vaccination decisions were most strongly influenced by the paediatricians the parents/guardians consulted. Although 97% of HCWs reported recommending the vaccine, only 43.7% of parents/guardians recalled receiving a recommendation.CONCLUSIONThese findings highlight the need for tailored vaccination communication, alongside timely, active physician recommendations and appropriate education to support HPV vaccination decisions.","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 41","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two incursions, two viruses: emergence of a second novel Shamonda virus clade, Germany, 2026. 两次入侵，两种病毒：第二种新型Shamonda病毒分支的出现，德国，2026。

IF 8.3 2区医学

Eurosurveillance Pub Date : 2026-10-01 DOI: 10.2807/1560-7917.ES.2026.31.39.2600756

Kerstin Wernike, Florian Pfaff, Sophie Zeiske, Dirk Höper, Martin Beer

引用次数: 0

Nosocomial outbreak of Ralstonia mannitolilytica associated with prefilled saline flush syringes distributed in Europe, Germany, March to September 2026. 2026年3月至9月在欧洲和德国分布的与预充盐水冲洗注射器相关的溶甘露醇拉尔斯顿菌的院内暴发

IF 8.3 2区医学

Eurosurveillance Pub Date : 2026-10-01 DOI: 10.2807/1560-7917.ES.2026.31.40.2600819

Sofia Burdi, Lukas Herrmann, Sophia N Koerdt, Silver A Wolf, Sandra Appelt, Mirco Sandfort, Barbara Maier, Sandra Reuter, Martin J Hug, Nicholas Jakob Böhm, Gizem Karadag, Georg Berndt, Achim Dörre, Vera Schwierzeck, Linda Behrends, Pascal Kreuzer, Julia Kuhn, Lukas Murajda, Saskia Roßbach, Susanne Kolbe-Busch, Cornelia Seidel, Patrick Jung, Grettel Chanto Chacón, Irina Zuschneid, Somayyeh Sedaghatjoo, Maximilian Driller Povill, Holger C Scholz, Alexander Mellmann, Tim Eckmanns, Josef Zündorf, Michael Hogardt, Sebastian Haller

{"title":"Nosocomial outbreak of Ralstonia mannitolilytica associated with prefilled saline flush syringes distributed in Europe, Germany, March to September 2026.","authors":"Sofia Burdi, Lukas Herrmann, Sophia N Koerdt, Silver A Wolf, Sandra Appelt, Mirco Sandfort, Barbara Maier, Sandra Reuter, Martin J Hug, Nicholas Jakob Böhm, Gizem Karadag, Georg Berndt, Achim Dörre, Vera Schwierzeck, Linda Behrends, Pascal Kreuzer, Julia Kuhn, Lukas Murajda, Saskia Roßbach, Susanne Kolbe-Busch, Cornelia Seidel, Patrick Jung, Grettel Chanto Chacón, Irina Zuschneid, Somayyeh Sedaghatjoo, Maximilian Driller Povill, Holger C Scholz, Alexander Mellmann, Tim Eckmanns, Josef Zündorf, Michael Hogardt, Sebastian Haller","doi":"10.2807/1560-7917.ES.2026.31.40.2600819","DOIUrl":"10.2807/1560-7917.ES.2026.31.40.2600819","url":null,"abstract":"A nosocomial outbreak of Ralstonia mannitolilytica bloodstream infections in Germany from March to September 2026 included 16 cases (≤ 6 allelic differences using core genome multilocus sequence typing) across seven hospitals. Epidemiological investigations supported by a large language model, identified prefilled saline flush syringes of one manufacturer as common exposure across all cases. The manufacturer initiated a temporary quarantine and suspension of use of this product. Because it was distributed to other countries, cases may have occurred elsewhere, prompting this report.","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 40","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elimination of congenital syphilis: a nationwide register-based study, Denmark, 2010 to 2024. 消除先天性梅毒：2010年至2024年丹麦一项基于全国登记的研究。

IF 8.3 2区医学

Eurosurveillance Pub Date : 2026-09-01 DOI: 10.2807/1560-7917.ES.2026.31.35.2600031

Ulrik Lausten-Thomsen, Steen Hoffmann, Paula Louise Hedley, Lene Holm Harritshøj, Jan Gorm Lisby, Marie Bækvad-Hansen, Michael Christiansen, Maria Wessman

{"title":"Elimination of congenital syphilis: a nationwide register-based study, Denmark, 2010 to 2024.","authors":"Ulrik Lausten-Thomsen, Steen Hoffmann, Paula Louise Hedley, Lene Holm Harritshøj, Jan Gorm Lisby, Marie Bækvad-Hansen, Michael Christiansen, Maria Wessman","doi":"10.2807/1560-7917.ES.2026.31.35.2600031","DOIUrl":"10.2807/1560-7917.ES.2026.31.35.2600031","url":null,"abstract":"BACKGROUNDCongenital syphilis is a potentially serious, but preventable infection. Several European countries have recently reported increasing trends.AIMThis study assessed national incidence and temporal trends of congenital syphilis and prevalence of pregnancies with active syphilis in Denmark between 2010 and 2024.METHODSUsing nationwide individual-level data linked through civil registration numbers across Danish health and population registers, we identified all maternal and congenital syphilis cases among live-born children born in Denmark from 2010 to 2024. We calculated annual incidence per 10,000 live births and analysed temporal trends and annual percent change (APC) with 95% confidence intervals (CI), using Poisson or negative binomial regression models.RESULTSFive infants with confirmed congenital syphilis were recorded among 894,345 live births, corresponding to an incidence of 0.6 per 100,000 (95% CI: 0.2-1.4). No infants with congenital syphilis were identified after 2016. For each infant, a plausible explanation for screening failure was identified: two women arrived in Denmark late in pregnancy, two were infected late in pregnancy. None of these events reflected failure of the first-trimester screening algorithm itself. One event was due to a reporting irregularity. Poisson regression showed a decreasing trend (APC = -21.7%; 95% CI: -43.4 to -1.0). Active syphilis infection occurred in 172 pregnancies, amounting to 20.0 per 100,000 live births (95% CI: 17.2-23.2) with no temporal changes.CONCLUSIONSCongenital syphilis is now eliminated in Denmark. The incidence of pregnancies with active syphilis infection remained stable despite increasing syphilis prevalence in the general population, confirming the continued effectiveness of the Danish national antenatal syphilis screening programme.","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 35","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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