Eurosurveillance最新文献

{"title":"Authors' response: Migrant tuberculosis in low-incidence Japan; introduction of pre-entry screening.","authors":"Gerard de Vries, Sarah Jackson, Brit Häcker, Teresa Domaszewska","doi":"10.2807/1560-7917.ES.2025.30.25.2500438","DOIUrl":"10.2807/1560-7917.ES.2025.30.25.2500438","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 25","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implicit bias in HIV testing based on indicator conditions in primary care: a population-based study in Catalonia, Spain, 2017 to 2021.","authors":"Cristina Agustí, Oriol Cunillera, Juanjo Mascort, Ricard Carrillo, Jordi Casabona","doi":"10.2807/1560-7917.ES.2025.30.24.2400585","DOIUrl":"10.2807/1560-7917.ES.2025.30.24.2400585","url":null,"abstract":"<p><p>BACKGROUNDHIV testing guided by indicator condition (IC) is recommended by the World Health Organization to facilitate earlier diagnosis. However, it is unclear to what extent these guidelines are followed in routine primary care (PC).AIMTo estimate the prevalence and distribution of ICs in PC in Catalonia, Spain, identify factors associated with, and prevalence of, an HIV test being administered, or not, within 4 months of IC diagnosis and assess trends over time.METHODSA population-based cross-sectional study was conducted using data from the Information System for the Development of Research in Primary Care, covering 5.8 million individuals in Catalonia. We identified IC episodes recorded from 1 January 2017 to 31 August 2021 among patients aged 16-65 years. For each IC episode, we assessed whether an HIV test was performed within 4 months.RESULTSWe identified 372,712 IC episodes; 84,694 (22.7%) led to an HIV test within 4 months. Testing was higher for: men (26.3% vs 19.4% for women); migrants (27.7% vs 21.3% for Spanish citizens); younger patients (29.2% for 16-30-year-olds vs 13.7% for those over 50 years). Testing rates were highest for episodes involving syphilis (68.4%), genital herpes (50.6%), chlamydia (48.2%) and gonorrhoea (43.1%). Factors associated with increased testing included male sex, higher socioeconomic deprivation area, presence of an acute sexually transmitted infection and multiple ICs.CONCLUSIONSubstantial gaps remain in HIV testing based on ICs in PC in Catalonia. Targeted interventions are needed to improve adherence to IC-guided testing, enabling early HIV diagnosis and treatment.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 24","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influenza vaccine effectiveness in Europe and the birth cohort effect against influenza A(H1N1)pdm09: VEBIS primary care multicentre study, 2023/24.","authors":"Esther Kissling, Marine Maurel, Francisco Pozo, Gloria Pérez-Gimeno, Silke Buda, Noémie Sève, Lisa Domegan, Mariëtte Hooiveld, Beatrix Oroszi, Iván Martínez-Baz, Raquel Guiomar, Neus Latorre-Margalef, Ivan Mlinarić, Mihaela Lazar, Jaume Giménez Duran, Ralf Dürrwald, Vincent Enouf, Adele McKenna, Marit de Lange, Gergő Túri, Camino Trobajo-Sanmartín, Verónica Gomez, Tove Samuelsson Hagey, Vesna Višekruna Vučina, Maria Carmen Cherciu, Miriam García Vazquez, Annika Erdwiens, Shirley Masse, Charlene Bennett, Adam Meijer, Katalin Kristóf, Jesús Castilla, Ana Paula Rodrigues, Sanja Kurečić Filipović, Alina Elena Ivanciuc, Sabrina Bacci, Marlena Kaczmarek","doi":"10.2807/1560-7917.ES.2025.30.23.2500011","DOIUrl":"10.2807/1560-7917.ES.2025.30.23.2500011","url":null,"abstract":"<p><p>IntroductionInfluenza A(H1N1)pdm09, A(H3N2) and B/Victoria viruses circulated in Europe in 2023/24, with A(H1N1)pdm09 dominance. First influenza infections in childhood may lead to different vaccine effectiveness (VE) in subsequent years.AimThe VEBIS primary care network estimated influenza VE in Europe using a multicentre test-negative study.MethodsPrimary care practitioners collected information and specimens from patients consulting with acute respiratory infection. We estimated VE against influenza (sub)type and clade, by age group and by year of age for A(H1N1)pdm09, using logistic regression.ResultsWe included 29,958 patients, with 3,054, 1,053 and 311 influenza A(H1N1)pdm09, A(H3N2) and B cases, respectively. All-age VE against influenza A(H1N1)pdm09 was 52% (95% CI: 44-59). By year of age, VE was 27% (95% CI: -2 to 47) at 44 years with peaks at 72% (95% CI: 52-84) and 54% (95% CI: 41-64) among children and those 65 years and older, respectively. All-age A(H1N1)pdm09 VE against clade 5a.2a was 41% (95% CI: 24-54) and -11% (95% CI: -69 to 26) against clade 5a.2a.1. The A(H3N2) VE was 35% (95% CI: 20-48) among all ages and ranged between 34% and 40% by age group. All-age VE against clade 2a.3a.1 was 38% (95% CI: 1-62). All-age VE against B/Victoria was 83% (95% CI: 65-94), ranging between 70 and 92% by age group.DiscussionThe 2023/24 VEBIS primary care VE against medically attended symptomatic influenza infection was high against influenza B/Victoria, but lower against influenza A(H1N1)pdm09 and A(H3N2). Clade- and age-specific effects may have played a role in the lower A(H1N1)pdm09 VE.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 23","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12164280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144283076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Plasmodium falciparum</i> malaria in six travellers returning from Zanzibar to Italy, December 2023 to February 2025: a case series.","authors":"Claudia Palazzolo, Angela Corpolongo, Serena Vita, Alessandra D'Abramo, Gaetano Maffongelli, Patrizia De Marco, Jingjing Lin, Silvia D'Arezzo, Marco Cilliano, Maria Laura Pettinato, Maria Grazia Bocci, Emanuele Nicastri","doi":"10.2807/1560-7917.ES.2025.30.25.2500412","DOIUrl":"10.2807/1560-7917.ES.2025.30.25.2500412","url":null,"abstract":"<p><p>Between December 2023 and February 2025, six cases of <i>Plasmodium falciparum</i> malaria were reported in travellers returning to Italy from Zanzibar, a popular tourist destination often perceived as low risk. None had taken prophylaxis, five had severe malaria and two died. Diagnostic delays revealed a lack of clinical suspicion of malaria and awareness among travellers and healthcare professionals. These cases highlight the importance of malaria chemoprophylaxis and prevention for travellers to risk areas in Africa, clinical suspicion and rapid testing.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 25","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Responsive population-based cohorts as platforms for characterising pathogen- and population-level infection dynamics for epidemic prevention, preparedness and response.","authors":"Ivonne Morales, Van Kính Nguyen, Mirna Abd El Aziz, Ayten Sultanli, Till Bärnighausen, Heiko Becher, Sandra Ciesek, Beate Kampmann, Berit Lange, Jan Rupp, Simone Scheithauer, Helen Ward, André Karch, Claudia M Denkinger","doi":"10.2807/1560-7917.ES.2025.30.25.2400255","DOIUrl":"10.2807/1560-7917.ES.2025.30.25.2400255","url":null,"abstract":"<p><p>Establishing population-based cohorts is indispensable for effective epidemic prevention, preparedness and response. Existing passive surveillance systems face limitations in their capacity to promptly provide representative data for estimating disease burden and modelling disease transmission. This perspective paper introduces a framework for establishing a dynamic and responsive nationally representative population-based cohort, with Germany as an example country. We emphasise the need for comprehensive demographic representation, innovative strategies to address participant attrition, efficient data collection and testing using digital tools, as well as novel data integration and analysis methods. Financial considerations and cost estimates for cohort establishment are discussed, highlighting potential cost savings through integration with existing research infrastructures and digital approaches. The framework outlined for creating, operating and integrating the cohort within the broader epidemiological landscape illustrates the potential of a population-based cohort to offer timely, evidence-based insights for robust public health interventions during both epidemics and pandemics, as well as during inter-epidemic periods.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 25","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular detection and isolation of clade Ib monkeypox virus, Canada, November 2024.","authors":"Mable Chan, Jonathan Audet, Jérémie Prévost, Karla Soriano, Kaylie Doan, Lauren Garnett, Yvon Deschambault, Sarah Medina, Marianne Stefopulos, Julia Paul, Santina Lee, Carol Kurbis, Bunmi Fatoye, Ana T Duggan, Katherine Eaton, Connor Chato, Darian Hole, Amber Papineau, Kerry Dust, Paul Van Caeseele, Yonette R Hercules, Shannon Gearhart, John Embil, Andrew Walkty, Donna Romaniuk, David Safronetz, James E Strong","doi":"10.2807/1560-7917.ES.2025.30.25.2500402","DOIUrl":"10.2807/1560-7917.ES.2025.30.25.2500402","url":null,"abstract":"<p><p>In November 2024, a case of clade Ib mpox was confirmed in Canada. Here, we describe the events that led to laboratory confirmation of clade Ib monkeypox virus (MPXV) and the public health response. Genomic analysis of the Canadian clade Ib MPXV revealed a number of APOBEC3-related mutations suggesting sustained human-to-human transmission. These findings expand the number of countries with travel-related clade Ib mpox and highlights the continued need for mpox monitoring of potential human adaptations or new transmission patterns.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 25","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hospital-onset bacteraemia and fungaemia as a novel automated surveillance indicator: results from four European university hospitals, 2018 to 2022.","authors":"Seven Js Aghdassi, Suzanne D van der Werff, Gaud Catho, Manon Brekelmans, Luis A Peña Diaz, Niccolò Buetti, Ferenc D Rüther, Daniel Teixeira, Daniel Sjöholm, Pontus Nauclér, Michael Behnke, Maaike Sm van Mourik","doi":"10.2807/1560-7917.ES.2025.30.24.2400613","DOIUrl":"10.2807/1560-7917.ES.2025.30.24.2400613","url":null,"abstract":"<p><p>BACKGROUNDConventional manual surveillance of healthcare-associated infections is labour-intensive and therefore often restricted to areas with high-risk patients. Fully automated surveillance of hospital-onset bacteraemia and fungaemia (HOB) may facilitate hospital-wide surveillance.AIMTo develop an algorithm and minimal dataset (MDS) required for automated surveillance of HOB and apply it to real-life routine data in four European hospitalsMETHODSThrough consensus discussion, a HOB definition with MDS suitable for automated surveillance was developed and applied in a retrospective multicentre observational study including all adult patients admitted to hospitals in the Netherlands, Germany, Sweden and Switzerland (2018-22). Annual HOB rates were calculated per 1,000 patient days for hospital, intensive care unit (ICU) and non-ICU settings.RESULTSHOB was defined as a positive blood culture with a recognised pathogen 2 or more days after hospital admission. For common commensals, two blood cultures with the same commensal within 2 days were required. HOB rates were comparable between the four hospitals (1.0-2.2/1,000 patient days). HOB rates were substantially higher in ICU than non-ICU settings, and HOB with common commensals accounted for 14.8-28.2% of all HOB. HOB rates per 1,000 patient days were consistent over time, but higher in 2020-21. HOB caused by <i>Staphylococcus aureus</i> comprised 8.4-16.0% of all HOB.CONCLUSIONAutomated HOB surveillance using a common definition was feasible and reproducible across four European hospitals. Future studies should investigate clinical relevance and preventability of HOB, and focus on strategies to make the automated HOB metric an actionable infection control tool.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 24","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of healthcare services preceding HIV diagnosis - missed opportunities for earlier diagnosis, Finland, 1996 to 2019.","authors":"Sanna Isosomppi, Mikaela Mutru, Jukka Ollgren, Henrikki Brummer-Korvenkontio, Kirsi Liitsola, Jussi Sutinen, Inka Aho, Pia Kivelä","doi":"10.2807/1560-7917.ES.2025.30.18.2400610","DOIUrl":"https://doi.org/10.2807/1560-7917.ES.2025.30.18.2400610","url":null,"abstract":"<p><p>BackgroundHIV testing based on indicator conditions is recommended to diagnose HIV earlier.AimOur aim was to assess opportunities for earlier diagnosis of HIV.MethodThis is a retrospective study on people living with HIV (PLWH) included in the national HIV register. We collected data on public primary outpatient healthcare (PHC) (2011-2019), secondary and tertiary outpatient healthcare (STHC), and all inpatient care (1996-2019) from the Care Register for Health Care from the presumed acquisition, estimated by CD4+ T-cell count at diagnosis, until the diagnosis of HIV.ResultsOf 907 PLWH diagnosed between 2011 and 2019, 522 (58%) had ≥ 1 healthcare contact at any level between HIV acquisition and > 30 days before diagnosis. At least one European Centre for Disease Prevention and Control (ECDC) indicator condition was recorded for 119 (23% of 522), and 112 (21%) were born in a high-prevalence country. In total, 384 of 907 (42%) had visited a PHC physician, and 58% of those with CD4+ T-cell count < 200 cells/μL at diagnosis. Of 2,082 PLWH diagnosed between 1996 and 2019, 869 (42%) had STHC outpatient contacts > 30 days before diagnosis, 18% with ≥ 1 ECDC indicator condition, and 367 (18%) had been hospitalised, 20% with ≥ 1 ECDC indicator condition. The most common ECDC indicator conditions > 30 days before diagnosis at all levels of healthcare were pneumonia, sexually transmitted infections, unexplained fever, herpes zoster, pregnancy and lymphadenopathy.ConclusionWe recommend enhancing indicator condition-based HIV testing by all healthcare providers, particularly for gonorrhoea, syphilis and, for persons younger than 50 years, also herpes zoster and lymphadenopathy.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 18","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12066979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human infections with Eurasian avian-like swine influenza virus detected by coincidence via routine respiratory surveillance systems, the Netherlands, 2020 to 2023.","authors":"Dirk Eggink, Annelies Kroneman, Jozef Dingemans, Gabriel Goderski, Sharon van den Brink, Mariam Bagheri, Pascal Lexmond, Mark Pronk, Erhard van der Vries, Evelien Germeraad, Diederik Brandwagt, Manon Houben, Mariëtte van Hooiveld, Joke van der Giessen, Rianne van Gageldonk-Lafeber, Ron Fouchier, Adam Meijer","doi":"10.2807/1560-7917.ES.2025.30.19.2400662","DOIUrl":"10.2807/1560-7917.ES.2025.30.19.2400662","url":null,"abstract":"<p><p>BackgroundZoonotic influenza, including infections with avian and swine influenza A viruses (swIAV), is a notifiable disease in the Netherlands. Human cases infected with swIAV have previously been rarely detected in the Netherlands.AimWe aimed to describe detection and characterisation of Eurasian avian-like swIAV infections in humans in the Netherlands 2020-2023.MethodsThe Dutch National Influenza Center coordinates different activities to monitor respiratory infections and circulating human influenza viruses. This monitoring includes sentinel surveillance in general practitioner practices, community participatory surveillance and characterisation of influenza viruses received from diagnostic laboratories. A subset of the specimens positive for influenza A virus from the monitoring activities are sent for further characterisation. We characterised swIAV from human patients using whole genome sequencing, tested the viruses for antiviral susceptibility and in haemagglutination inhibition assays for antigenic characterisation and compared them with previous detections from humans and pigs.ResultsAvian-like swine influenza virus was detected in three persons presenting with mild respiratory symptoms, and all recovered fully. Only one patient had close contact with pigs shortly before the start of symptoms. Sequence analyses of the viruses showed clustering with swAIV from pigs in a recently initiated surveillance system on pig farms.ConclusionsThese human cases show that swIAV viruses with zoonotic potential are enzootic in the Netherlands. Finding them by coincidence suggests human infections might occur more frequently than noticed.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 19","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12083066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Klebsiella aerogenes</i> ST117 causing folliculitis in men having sex with men, Belgium, February 2025.","authors":"Nicolas Yin, Jonathan Krygier, Célestin Mairesse, Agnès Libois, Sophie Quoilin, Delphine Martiny","doi":"10.2807/1560-7917.ES.2025.30.20.2500304","DOIUrl":"10.2807/1560-7917.ES.2025.30.20.2500304","url":null,"abstract":"<p><p><i>Klebsiella aerogenes</i> has recently been reported as a causative agent of folliculitis in men who have sex with men (MSM). We present four cases of folliculitis in MSM diagnosed in Brussels, Belgium. Patients were aged between 25 and 50 years, and all were infected by a single multilocus sequence type (ST117) strain. This strain carried the yersiniabactin siderophore genes. Following a preliminary treatment by sulfamethoxazole-trimethoprim for 7-14 days, all patients experienced a recurrence of symptoms, necessitating an extended therapeutic regimen.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"30 20","pages":""},"PeriodicalIF":9.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}