Eurosurveillance最新文献

{"title":"Job vacancy at the European Centre for Disease Prevention and Control (ECDC).","authors":"","doi":"10.2807/1560-7917.ES.2026.31.38.202609244","DOIUrl":"10.2807/1560-7917.ES.2026.31.38.202609244","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 38","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13615384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149037415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early impact of maternal RSV vaccination on bronchiolitis hospitalisation and critical care admissions in infants under age 3 months, England, September 2024 to March 2026.","authors":"Jonathan Broad, Matthew Wilson, Jaime Borjas-Howard, Merryn Voysey, Simon B Drysdale, Nick Andrews, Conall H Watson, Heather J Whitaker","doi":"10.2807/1560-7917.ES.2026.31.36.2600752","DOIUrl":"10.2807/1560-7917.ES.2026.31.36.2600752","url":null,"abstract":"<p><p>We conducted a time series analysis of hospitalisation and critical care admissions to evaluate the impact of maternal respiratory syncytial virus (RSV) vaccination in England from September 2024 to March 2026 in infants < 3 months of age. All bronchiolitis admissions decreased by 39.3% (IRR: 0.607, 95% CI: 0.576-0.640), and RSV bronchiolitis admissions by 62.6% (IRR: 0.374, 95% CI: 0.344-0.407). We estimated a 41.0% reduction in bronchiolitis critical care admissions (IRR: 0.590, 95% CI: 0.531-0.657). Maternal vaccine coverage was 55.1%. These findings support efforts to expand vaccine uptake.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 36","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and outcomes of adult patients hospitalised with RSV infection, influenza or COVID-19 in Belgium, winter seasons 2023/24 and 2024/25.","authors":"Yves Lafort, Cato Dambre, Yinthe Dockx, Anna Parys, Xavier Holemans, Marie-Pierre Parsy, Nicolas Dauby, Marijke Reynders, Marc Bourgeois, Arne Witdouck, Isabel Leroux-Roels, Eva Bernaert, Koen Magerman, Laura Cornelissen, Laurane De Mot","doi":"10.2807/1560-7917.ES.2026.31.37.2600088","DOIUrl":"10.2807/1560-7917.ES.2026.31.37.2600088","url":null,"abstract":"<p><p>BACKGROUNDSevere acute respiratory infections (SARI) cause substantial disease burden in older adults and those with comorbidities.AIMTo inform Belgian vaccination policies, we aimed to compare risk profiles and outcomes of influenza, COVID-19 and RSV infections and examine age-related differences.METHODSAdults (≥ 18 years) hospitalised with SARI in nine Belgian sentinel hospitals during the 2023/24 and 2024/25 winter seasons were included. Patients with laboratory-confirmed RSV infection, influenza or COVID-19 were compared in terms of demographics, comorbidities, complications and outcomes. Adults 18-64 years were compared with those ≥ 65 years. Multivariate analyses were applied.RESULTSAmong 2,806 patients, 535 (19.1%) had RSV infection, 1,694 (60.4%) influenza and 577 (20.6%) COVID-19. Patients with influenza were significantly younger (mean age 68.9 years) and had significantly fewer comorbidities (89.7%) than patients with RSV (73.8 years; 95.8%) or COVID-19 (74.0 years; 93.6%). Patients with COVID-19 experienced significantly fewer complications (40.8%) than patients with RSV (48.9%) or influenza (45.2%). Patients with RSV had higher in-hospital mortality (11.9%) than patients with influenza (7.3%; p = 0.089) or COVID-19 (6.9%; p = 0.037). Across pathogens, younger adults had relatively more comorbidities after adjusting for differences in the general population. They had shorter hospital stays and lower mortality, but higher intensive care unit admission rates.CONCLUSIONPatients with RSV infection had a disease course comparable to patients with influenza or COVID-19 and a higher mortality rate, especially with increasing age. These findings highlight the importance of RSV vaccination in older adults and those with comorbidities, alongside established vaccination strategies for seasonal influenza and COVID-19.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 37","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of nirsevimab-resistant RSV-B variants in children carrying the F:N201T substitution through genomic surveillance, Spain, 2025/26 season.","authors":"María Iglesias-Caballero, Jose A Infantes, Albert Campoy, Sara Camarero-Serrano, Silvia Moreno, Olga Cano, Germán Vallejo-Palma, Carmen González-Velasco, Cristina Gaona, Pedro Camacho-Martinez, Laura Merino-Diaz, Sonia Vázquez-Morón, Francisco Pozo, Jose A Lepe, Vicente Mas, Inmaculada Casas","doi":"10.2807/1560-7917.ES.2026.31.35.2600690","DOIUrl":"10.2807/1560-7917.ES.2026.31.35.2600690","url":null,"abstract":"<p><p>During Spain's 2025/26 RSV season, three children were infected with RSV-B viruses carrying the F protein N201T substitution. Two who received nirsevimab that season were hospitalised (one required intensive care); the third was treated previously. Recombinant expression studies confirmed reduced nirsevimab recognition. Genomic data indicated sporadic emergence across distinct RSV-B backgrounds rather than expansion of a single lineage. Findings highlight the importance of combining genomic surveillance with antigenic characterisation to detect and interpret variants with reduced susceptibility to antibody-based prevention.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 35","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autochthonous chikungunya virus (CHIKV) outbreak in the province of Modena, Emilia-Romagna region, Italy, August to October 2025: epidemiology, clinical features and virological findings.","authors":"Giada Rossini, Giulio Matteo, Paola Angelini, Mattia Calzolari, Rodolfo Veronesi, Alessandra Fantuzzi, Caterina Vocale, Silvia Galli, Liliana Gabrielli, Michele Dottori, Riccardo Mazzoli, Tommaso Filippini, Maurilia Marcacci, Guido Di Donato, Giovanna Mattei, Tiziana Lazzarotto","doi":"10.2807/1560-7917.ES.2026.31.36.2500962","DOIUrl":"10.2807/1560-7917.ES.2026.31.36.2500962","url":null,"abstract":"<p><p>Between 10 August and 31 October 2025, 343 cases (306 confirmed and 37 probable) of symptomatic autochthonous chikungunya virus (CHIKV) infection were notified in eight municipalities in the province of Modena, Emilia-Romagna region, northern Italy. The infection was diagnosed by detection of CHIKV RNA in blood and urine samples, and by detection of IgM antibodies against CHIKV. Most common symptoms were arthralgia (n = 326) and fever (n = 317). No fatalities were reported. Chikungunya virus RNA was detected in 39 (14.8%) of 263 pools of <i>Aedes albopictus</i> mosquitoes, thereby confirming local vector-borne transmission. Sequences from 11 case samples and two mosquito pools were whole genome sequenced. The viral strain belonged to the East/Central/South African (ECSA) lineage 2 and was closely related to the strains circulating in Reunion Island in 2024-25. The public health response included rapid vector control measures, reinforced epidemiological surveillance and multidisciplinary coordination between public health authorities and clinicians, laboratories and entomologists. This was one of the largest autochthonous CHIKV outbreaks ever recorded in a temperate European region. It highlights the critical importance of integrated, multidisciplinary preparedness and response for arboviral threats in non-endemic areas.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 36","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Celebrating 30 years of partnership with the European field epidemiology training programmes.","authors":"","doi":"10.2807/1560-7917.ES.2026.31.35.202609031","DOIUrl":"10.2807/1560-7917.ES.2026.31.35.202609031","url":null,"abstract":"","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 35","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging trends in invasive <i>Streptococcus dysgalactiae</i> subsp. <i>equisimilis</i> infections in Denmark, 2014 to 2024: a nationwide genomic and registry-based study.","authors":"Jana Grüttner, Aoife Ronayne, Raphael Niklaus Sieber, Thor Bech Johannesen, Zahraa Chayed, Esad Dzajic, Ulrich Stab Jensen, David Fuglsang-Damgaard, Marianna Konoy, Lars Lemming, Xiaohui Chen Nielsen, Emma Julia Petronella Nilsson Gram, Claus Østergaard, Michael Pedersen, Steen Hoffmann, Marc Stegger","doi":"10.2807/1560-7917.ES.2026.31.35.2500714","DOIUrl":"10.2807/1560-7917.ES.2026.31.35.2500714","url":null,"abstract":"<p><p>BACKGROUNDIncreasing incidence rates of invasive <i>Streptococcus dysgalactiae</i> subspecies <i>equisimilis</i> (iSDSE) have been detected worldwide.AIMWe aimed to investigate iSDSE infection incidence rates in Denmark during 2014-2024, and characterise the genomic population structure of a subset of iSDSE isolates and their antimicrobial resistance (AMR).METHODSUsing national register data, we estimated overall and sex-/age-stratified iSDSE incidences during 2014-2024, by retrospectively identifying cases of invasive infections with group C and G streptococci or <i>S. dysgalactiae</i> (including specified as subspecies <i>equisimilis</i>). From the voluntary national beta-haemolytic streptococci laboratory surveillance system, whole-genome-sequenced isolates from August 2020-September 2022 were used to investigate the iSDSE genomic population structure. Susceptibility to penicillin, erythromycin and clindamycin was determined and AMR genes identified.RESULTSDuring 2014-2024, iSDSE incidence rates increased significantly (linear trend analysis p < 0.001) with mean annual incidence ranging between 10.3 and 16.4 per 100,000, peaking in 2023. Incidence was higher in males, increasing with older age. Nearly 75% of the 1,223 iSDSE isolates belonged to four of 14 genetic clusters. Sequence types (STs) ST20 and ST17 were most prevalent, while <i>emm</i>-type <i>stG62647</i>, a variant associated internationally with higher virulence, dominated. All isolates were phenotypically susceptible to penicillin but approximately 10% were respectively erythromycin and clindamycin resistant. High erythromycin resistance prevalence (57%; 39/68), coinciding with gene <i>ermA</i>, occurred in one genetic cluster.CONCLUSIONThe findings illustrate the need for national registry-based surveillance to detect epidemiological changes and potential outbreaks. Further, continuous genomic surveillance can monitor the occurrence and expansion of genetic clades and AMR genes.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 35","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thirty years of an advanced field epidemiology training programme: a mixed-methods evaluation, Germany, 1996 to 2025.","authors":"Simon Brinkwirth, Lena Ella Schneider, Ida Sperle, Petra von Berenberg-Gossler, Katharina Alpers, Sofie Gillesberg Lassen","doi":"10.2807/1560-7917.ES.2026.31.35.2600395","DOIUrl":"10.2807/1560-7917.ES.2026.31.35.2600395","url":null,"abstract":"<p><p>INTRODUCTIONField epidemiology training programmes (FETPs) strengthen public health workforce capacity for infectious disease surveillance and outbreak response. The Postgraduate Training for Applied Epidemiology (PAE) is a 2-year FETP aligned with European and global training standards.AIMWe evaluated the contribution of PAE to a strengthened public health workforce for infection protection in Germany.METHODSOur evaluation consisted of three components: a semi-structured desk review of programme outputs (1996-2025), an online graduate survey (cohorts 1996-2023), and an online workshop with experts from local, federal state and national health authorities. We analysed quantitative data descriptively, and qualitative data through a simplified content analysis.RESULTSBy December 2025, PAE had 126 graduates with the following outputs: 197 peer-reviewed publications, 193 accepted conference abstracts, and 205 conducted outbreak investigations. In total, 72% (91/126) graduates responded to the survey. Most respondents remained in the German public health workforce (70%; 64/91), reported high satisfaction (90%; 82/91), and would recommend the programme (96%; 87/91). Graduates reported roles in crisis and outbreak management (70%; 64/91), holding leadership roles (59%; 54/91), and engaging in knowledge dissemination (86%; 78/91). Qualitative findings highlighted shared methodological approaches and technical language, and strong networks as key facilitators of collaboration across all levels of the German public health service.CONCLUSIONWe found that PAE contributes to strengthening and sustaining an infection protection workforce in Germany that regularly applies and disseminates learnt skills. Most graduates have held or currently hold leadership roles and frequently contribute to outbreak and public health crisis management.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 35","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13545520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An outbreak of Panton-Valentine leucocidin-producing meticillin-resistant <i>Staphylococcus aureus</i> skin and soft tissue infection associated with bouncy castle use, Ireland, 2025.","authors":"Domhnall McGlacken-Byrne, Gráinne Brennan, Eimear Kitt, Keith Ian Quintyne, Eimear Brannigan, Máirín Boland, Andrea King, Michael Barrett, Noelle O'Loughlin, Desmond Hickey","doi":"10.2807/1560-7917.ES.2026.31.36.2500975","DOIUrl":"10.2807/1560-7917.ES.2026.31.36.2500975","url":null,"abstract":"<p><p>We describe an outbreak of Panton-Valentine leucocidin (PVL) producing community-acquired meticillin-resistant <i>Staphylococcus aureus</i> (CA-MRSA) in children and adolescents in eastern Ireland, associated with bouncy castle use. Regional public health authorities were notified in autumn 2025 of several hospital presentations by children and adolescents with skin and soft tissue infection (SSTI). An outbreak was declared. Phone interviews were conducted with a parent or guardian of each case, obtaining demographic, clinical and exposure information. All 48 identified cases were children and adolescents. Of these, 47 attended the same outdoor social gathering in autumn 2025 which featured bouncy castle play. Case definitions were drafted and iteratively refined. The commonest affected body site was the legs, particularly thighs. Thirty-three cases were treated by their general practitioner (GP). A further 15 attended a hospital emergency department or day ward, of whom four were hospitalised, with no deaths. All confirmed cases exhibited an identical strain type, t016-ST22-MRSA-IV, which was PVL-producing. This strain has been described as hypervirulent but is rare in Ireland. The causal isolate exhibited a distinctive antibiogram. Key control measures for this complex outbreak included early recognition of linked cases, rapid delivery of clinical care, and infection prevention and control measures.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 36","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying socioeconomic characteristics of pregnant women aged 15-50 years diagnosed with HIV during pregnancy, the Netherlands, 2016 to 2023.","authors":"Colette Smit, Vita Jongen, Jeannine Nellen, Tania Mudrikova, Elisabeth van Leeuwen, Nina Schat, Rosan van Zoest, Ard van Sighem, Eline Op de Coul, Marc van der Valk","doi":"10.2807/1560-7917.ES.2026.31.37.2600048","DOIUrl":"10.2807/1560-7917.ES.2026.31.37.2600048","url":null,"abstract":"<p><p>BACKGROUNDPregnant women in the Netherlands are screened for HIV during the first trimester. Insight into characteristics of women diagnosed with HIV may help identify groups who could benefit from testing strategies.AIMWe assessed the contribution of HIV diagnoses during pregnancy to the total number of diagnoses among women in the Netherlands between 2016 and 2023 and identified socioeconomic characteristics of women with an antenatal diagnosis.METHODSIn a cross-sectional analysis, we selected women aged 15-50 years registered in the national ATHENA cohort and diagnosed with HIV in the Netherlands. Each pregnant woman with HIV was matched by year of pregnancy to three pregnant women without HIV from the general population using non-public registry data from Statistics Netherlands. Characteristics were examined using multivariable logistic regression.RESULTSNinety-two of 523 women with HIV were diagnosed during pregnancy. These women less often had an advanced HIV infection than non-pregnant women with HIV (22 vs. 47%). Eighty-three of 92 pregnant women with HIV were matched with 249 pregnant women without HIV. Being diagnosed during pregnancy was associated with first- (aOR: 14.1; 95% CI: 6.45-30.6) or second-generation migration background (aOR: 5.38; 95% CI:2.02-11.0), income below the poverty line (aOR: 3.46; 95% CI: 1.28-9.34) and living in a single-parent household (aOR: 3.46; 95% CI: 1.52-7.88).CONCLUSIONAntenatal HIV diagnoses accounted for a substantial part of diagnoses among women; pregnant women were less likely to present with advanced-stage disease. These findings show the importance of universal antenatal HIV screening.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":"31 37","pages":""},"PeriodicalIF":8.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}