Coxsackievirus B4 (CV-B4) linked to four severe neonatal infections including one fatal, Northern Ireland, October 2024 to February 2025.

IF 9.9 2区医学 Q1 INFECTIOUS DISEASES

Eurosurveillance Pub Date : 2025-05-01 DOI:10.2807/1560-7917.ES.2025.30.21.2500317

Susan A Feeney, Marie Clare Crilly, Sharon Christie, Julie Lewis, Anne Eilis McColgan, Marc Niebel, James P McKenna

引用次数: 0

Abstract

We report four cases of severe neonatal non-polio enterovirus infection, requiring hospital admission. Infants presented to different regional hospitals across Northern Ireland from late 2024 to early 2025. Three had neonatal meningitis and one showed rapid demise, leading to sepsis, multi-organ failure and death at day 6 of life. All infants were less than 18 days old at presentation, two were considered congenital infections, with one presenting symptoms at birth. All infants had detectable enterovirus RNA, typed as coxsackievirus B4.

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柯萨奇病毒B4 （CV-B4）与2024年10月至2025年2月在北爱尔兰发生的4例严重新生儿感染有关，包括1例致命感染。

我们报告四例严重的新生儿非脊髓灰质炎肠道病毒感染，需要住院治疗。从2024年底到2025年初在北爱尔兰不同地区医院就诊的婴儿。其中3例患有新生儿脑膜炎，1例出现快速死亡，导致败血症、多器官衰竭，并在出生后第6天死亡。所有婴儿出生时均小于18天，其中2例被认为是先天性感染，1例在出生时出现症状。所有婴儿均可检测到柯萨奇病毒B4型肠病毒RNA。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Eurosurveillance INFECTIOUS DISEASES-

CiteScore

32.70

自引率

2.10%

发文量

430

审稿时长

3-8 weeks

期刊介绍： Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.