European journal of preventive cardiology最新文献

{"title":"New Diagnosis of Diabetes in Patients with Myocardial Infarction or Stroke: A Systematic Review and Meta-analysis.","authors":"Marwa Douelrachad, Alexander Thistle, Hibo Rijal, Ari Ochuba, Calvin Ke, Charlotte Lee, Manav V Vyas","doi":"10.1093/eurjpc/zwaf286","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf286","url":null,"abstract":"<p><strong>Background: </strong>What proportion of patients with an acute myocardial infarction (MI) or stroke get a new diagnosis of diabetes (NDD) at the time of hospitalization is unclear.</p><p><strong>Methods: </strong>We systematically searched MEDLINE and Embase from database inception to January 30, 2025, to select English-language observational studies that included adult patients with MI or stroke and reported the number of patients with NDD. The denominator was patients without diabetes. Study quality was assessed using the Joanna Briggs Institute (JBI) checklist. Random effects meta-analyses were used to calculate the pooled proportion of NDD in patients with MI or stroke. Heterogeneity was explored in subgroup analyses, and any change over time was evaluated using meta-regression.</p><p><strong>Results: </strong>82 studies that included 9440 patients with NDD were identified. Included studies were of good methodological quality: 17 (22%) tested all eligible patients for diabetes, and 19 (23%) used registry-based samples. 16.0% (95% confidence interval, 14.3 to 17.7, n = 52) patients with MI had NDD, and 15.3% (95% CI 12.5 to 18.0, n = 30) patients with stroke had NDD, albeit with high heterogeneity. The pooled proportion was higher when OGTT was used to diagnose diabetes. The proportion of NDD did not change over the last 30 years (0.1% per year decline; 95% CI -0.3% to 0.1%).</p><p><strong>Conclusions: </strong>Among patients admitted with MI or stroke, one in six gets a new diagnosis of diabetes. Improving diabetes screening could help identify people before having a diabetes-related cardiovascular event.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Life's Essential 8 Score Reduces the Risk of Aortic Valve Calcification.","authors":"Man Gui, Shuohua Chen, Yihao Qi, Jianjiao Wang, Ying Gao, Ying Han, Jialing Deng, Maoxiang Zhao, Peipei Liu, Naihui Zhao, Lu Guo, Shouling Wu, Fengmei Xing","doi":"10.1093/eurjpc/zwaf285","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf285","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to investigate the association between Life's Essential 8 (LE8) and Aortic Valve Calcification (AVC) and to evaluate whether a high LE8 score can effectively reduce the risk of AVC.</p><p><strong>Methods: </strong>This study included 30,561 participants from the Kailuan cohort who completed the Kailuan health examination and underwent ultrasound evaluations. A multifactorial logistic regression analysis was used to assess the relationship between LE8 score and AVC, along with subgroup analyses and an analysis of the impact of each component of LE8 on AVC.</p><p><strong>Results: </strong>Among the 30,561 participants, 3,717(12.16%) cases of AVC were detected, with a detection rate of 12.16%. The detection rate of AVC significantly decreased with increased LE8 (P<0.001). The risk of AVC was reduced by 34% in the moderate Cardiovascular Health (CVH) group (OR=0.66, 95% CI 0.60-0.72) and by 63% in the high CVH group (OR=0.37, 95% CI 0.27-0.50). For each standard deviation increase in the LE8 score, the risk of AVC decreased by 23% (OR=0.77, 95% CI 0.74-0.80). Analysis of the individual components of LE8 revealed that diet, exercise, body mass index, blood lipids, blood glucose, and blood pressure were all associated with the reduced risk of AVC. In contrast, no impact of sleep and smoking on AVC risk was observed.</p><p><strong>Conclusions: </strong>The study indicates that a high LE8 score was associated with low AVC risk, suggesting a new prevention strategy through healthy behaviors and lifestyle changes.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal trend and attributable risk factors of cardiovascular disease burden for adults 55 years and older in 204 countries/territories from 1990 to 2021: an analysis for the Global Burden of Disease Study 2021.","authors":"Ming-Si Wang, Jing-Wen Deng, Wan-Yue Geng, Rui Zheng, Hui-Lin Xu, Ying Dong, Wei-Dong Huang, Yi-Lan Li","doi":"10.1093/eurjpc/zwae384","DOIUrl":"10.1093/eurjpc/zwae384","url":null,"abstract":"<p><strong>Aims: </strong>The ageing global population and overall population growth have significantly increased the burden of cardiovascular diseases (CVDs). This study aims to examine global temporal trends in the incidence, disability-adjusted life years (DALYs), and mortality rates of both overall and type-specific CVDs among adults aged 55 and older from 1990 to 2021, with a focus on identifying changes over time, regional disparities, and the key risk factors contributing to this burden.</p><p><strong>Methods and results: </strong>We analysed data from the Global Burden of Disease Study 2021, covering 204 countries and territories. Trends in age-standardized rates of incidence, DALY, and mortality for both overall and specific types of CVDs were assessed, alongside the impact of key risk factors. Between 1990 and 2021, global age-standardized incidence, DALY, and mortality rates showed a declining trend, with estimated annual percentage changes of -0.39, -1.30, and -1.11, respectively. However, due to overall population growth and ageing, the absolute number of CVD cases continued to rise. Regions with high-middle socio-demographic index (SDI) exhibited the highest incidence and mortality rates, while high SDI regions saw the greatest declines. Men had higher age-standardized rates of CVD incidence, DALY, and mortality compared with women. The burden increased with age, with the oldest age groups (80+ years) showing the highest rates. High systolic blood pressure was the leading modifiable risk factor, contributing to more than half of the CVD-related DALY globally. Other major risk factors included high LDL cholesterol, smoking, and ambient particulate matter pollution.</p><p><strong>Conclusion: </strong>While age-standardized rates of CVD incidence, DALY, and mortality have declined over the past three decades, the total burden of CVDs continues to rise due to population ageing and growth. These findings highlight the need for targeted prevention strategies in regions with high CVD burden, particularly those with lower socioeconomic status.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"539-552"},"PeriodicalIF":8.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142727362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation and improvements in cardiovascular risk estimation.","authors":"Ilham Benzidia, Victor Aboyans","doi":"10.1093/eurjpc/zwaf183","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf183","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":"32 7","pages":"513-515"},"PeriodicalIF":8.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"External validation and comparison of six cardiovascular risk prediction models in the Prospective Urban Rural Epidemiology (PURE)-Colombia study.","authors":"Jose P Lopez-Lopez, Angel A Garcia-Pena, Daniel Martinez-Bello, Ana M Gonzalez, Maritza Perez-Mayorga, Oscar Mauricio Muñoz Velandia, Gabriela Ruiz-Uribe, Alfonso Campo, Sumathy Rangarajan, Salim Yusuf, Patricio Lopez-Jaramillo","doi":"10.1093/eurjpc/zwae242","DOIUrl":"10.1093/eurjpc/zwae242","url":null,"abstract":"<p><strong>Aims: </strong>To externally validate the SCORE2, AHA/ACC pooled cohort equation (PCE), Framingham Risk Score (FRS), Non-Laboratory INTERHEART Risk Score (NL-IHRS), Globorisk-LAC, and WHO prediction models and compare their discrimination and calibration capacity.</p><p><strong>Methods and results: </strong>Validation in individuals aged 40-69 years with at least 10 years of follow-up and without baseline use of statins or cardiovascular diseases from the Prospective Urban Rural Epidemiology (PURE)-Colombia prospective cohort study. For discrimination, the C-statistic, and receiver operating characteristic curves with the integrated area under the curve (AUCi) were used and compared. For calibration, the smoothed time-to-event method was used, choosing a recalibration factor based on the integrated calibration index (ICI). In the NL-IHRS, linear regressions were used. In 3802 participants (59.1% women), baseline risk ranged from 4.8% (SCORE2 women) to 55.7% (NL-IHRS). After a mean follow-up of 13.2 years, 234 events were reported (4.8 cases per 1000 person-years). The C-statistic ranged between 0.637 (0.601-0.672) in NL-IHRS and 0.767 (0.657-0.877) in AHA/ACC PCE. Discrimination was similar between AUCi. In women, higher over-prediction was observed in the Globorisk-LAC (61%) and WHO (59%). In men, higher over-prediction was observed in FRS (72%) and AHA/ACC PCE (71%). Overestimations were corrected after multiplying by a factor derived from the ICI.</p><p><strong>Conclusion: </strong>Six prediction models had a similar discrimination capacity, supporting their use after multiplying by a correction factor. If blood tests are unavailable, NL-IHRS is a reasonable option. Our results suggest that these models could be used in other countries of Latin America after correcting the overestimations with a multiplying factor.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"564-572"},"PeriodicalIF":8.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12066169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of visit-to-visit lipid variability with coronary artery calcification and cardiovascular event in statin-naïve Koreans.","authors":"Jeonggyu Kang, Byung Jin Kim","doi":"10.1093/eurjpc/zwaf191","DOIUrl":"10.1093/eurjpc/zwaf191","url":null,"abstract":"<p><strong>Aims: </strong>This study investigated the association of visit-to-visit lipid variability with both coronary artery calcification (CAC) and cardiovascular event risk among statin-naïve individuals.</p><p><strong>Methods and results: </strong>We conducted a cross-sectional analysis of 59 879 participants whose lipid profiles were measured 4-6 times before or on the day of CAC scanning and a cohort study of 85 359 individuals who underwent at least five lipid tests with additional follow-up to identify cardiovascular events. Lipid variability was quantified using standard deviation, coefficient of variation, and variability independent of the mean (VIM). Cardiovascular events were identified using self-reported coronary artery disease and stroke. Among lipid profiles, the highest quartile of low-density lipoprotein cholesterol (LDL-C) variability (VIM) showed a 1.42-fold increased CAC score [95% confidence interval (CI): 1.22-1.65] compared to the lowest quartile. Furthermore, the VIM for total cholesterol, triglyceride, and non-high-density lipoprotein cholesterol levels was positively associated with CAC scores. During a median follow-up of 2.8 years, 664 cases of cardiovascular events were identified. Among the lipid profiles, only LDL-C variability was associated with an increased risk of cardiovascular events, with a hazard ratio of 1.41 (95% CI: 1.13-1.75) for those with the highest VIM variability.</p><p><strong>Conclusion: </strong>These findings suggest that visit-to-visit lipid variability is independently associated with subclinical coronary atherosclerosis and cardiovascular risk in statin-naïve individuals. Clinicians need to be aware of the potential implications of lipid variability and consider monitoring lipid fluctuations as part of a comprehensive cardiovascular risk assessment.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of variability in risk factors on cardiovascular disease outcomes in type 2 diabetes mellitus.","authors":"Jamol Uzokov","doi":"10.1093/eurjpc/zwad181","DOIUrl":"10.1093/eurjpc/zwad181","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"610-611"},"PeriodicalIF":8.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9605299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter by Wu et al Regarding Article, \"A comprehensive analysis of the impact of high-intensity interval vs. moderate-intensity continuous training on global and regional myocardial function in patients early after acute myocardial infarction-the STRAICT randomized controlled trial\".","authors":"HuiHui Wu, Zhihai Jiang, Lei Zheng","doi":"10.1093/eurjpc/zwaf289","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf289","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging continents: recalibration of SCORE2-Diabetes to China.","authors":"Jannick A N Dorresteijn","doi":"10.1093/eurjpc/zwaf291","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf291","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adding traditional and emerging biomarkers for risk assessment in secondary prevention: a prospective cohort study of 20 656 patients with cardiovascular disease.","authors":"Ike Dhiah Rochmawati, Salil Deo, Jennifer S Lees, Patrick B Mark, Naveed Sattar, Carlos Celis-Morales, Jill P Pell, Paul Welsh, Frederick K Ho","doi":"10.1093/eurjpc/zwae352","DOIUrl":"10.1093/eurjpc/zwae352","url":null,"abstract":"<p><strong>Aims: </strong>This study aims to explore whether conventional and emerging biomarkers could improve risk discrimination and calibration in the secondary prevention of recurrent atherosclerotic cardiovascular disease (ASCVD), based on a model using predictors from SMART2 (Secondary Manifestations of ARTerial Disease).</p><p><strong>Methods and results: </strong>In a cohort of 20 658 UK Biobank participants with medical history of ASCVD, we analysed any improvement in C indices and net reclassification index (NRI) for future ASCVD events, following addition of lipoprotein A (LP-a), apolipoprotein B, Cystatin C, Hemoglobin A1c (HbA1c), gamma-glutamyl transferase (GGT), aspartate aminotransferase (AST), alanine aminotransferase, and alkaline phosphatase (ALP), to a model with predictors used in SMART2 for the outcome of recurrent major cardiovascular event. We also examined any improvement in C indices and NRIs replacing creatinine-based estimated glomerular filtration rate (eGFR) with Cystatin C-based estimates. Calibration plots between different models were also compared. Compared with the baseline model (C index = 0.663), modest increments in C indices were observed when adding HbA1c (ΔC = 0.0064, P < 0.001), Cystatin C (ΔC = 0.0037, P < 0.001), GGT (ΔC = 0.0023, P < 0.001), AST (ΔC = 0.0007, P < 0.005) or ALP (ΔC = 0.0010, P < 0.001) or replacing eGFRCr with eGFRCysC (ΔC = 0.0036, P < 0.001) or eGFRCr-CysC (ΔC = 0.00336, P < 0.001). Similarly, the strongest improvements in NRI were observed with the addition of HbA1c (NRI = 0.014) or Cystatin C (NRI = 0.006) or replacing eGFRCr with eGFRCr-CysC (NRI = 0.001) or eGFRCysC (NRI = 0.002). There was no evidence that adding biomarkers modified calibration.</p><p><strong>Conclusion: </strong>Adding several biomarkers, most notably Cystatin C and HbA1c, but not LP-a, in a model using SMART2 predictors modestly improved discrimination.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"585-595"},"PeriodicalIF":8.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}