{"title":"Lipoprotein (a) and atherosclerotic cardiovascular disease: does high-sensitive C-reactive protein contribute and quo vadis?","authors":"Daniel A Duprez, David R Jacobs","doi":"10.1093/eurjpc/zwaf015","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf015","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Positive medicine to prevent non-communicable disease.","authors":"Rachel E Climie, Jean-Philippe Empana","doi":"10.1093/eurjpc/zwaf003","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf003","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luigina Guasti, Stefano Fumagalli, Jonathan Afilalo, Tobias Geisler, Ana Abreu, Marco Ambrosetti, Sofie Gevaert, Ruxandra Christodorescu, Dimitri Richter, Victor Aboyans, Lucie Chastaingt, Michela Barisone, Paolo Severgnini, Riccardo Asteggiano, Marc Ferrini
{"title":"Cardiovascular diseases, prevention and management of complications in older adults and frail patients treated for elective or post-traumatic hip orthopaedic interventions.","authors":"Luigina Guasti, Stefano Fumagalli, Jonathan Afilalo, Tobias Geisler, Ana Abreu, Marco Ambrosetti, Sofie Gevaert, Ruxandra Christodorescu, Dimitri Richter, Victor Aboyans, Lucie Chastaingt, Michela Barisone, Paolo Severgnini, Riccardo Asteggiano, Marc Ferrini","doi":"10.1093/eurjpc/zwaf010","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf010","url":null,"abstract":"<p><p>Due to the aging population, focusing on healthy aging has become a global priority. Cardiovascular diseases (CVDs) and frailty, characterized by increased vulnerability to adverse stress and health events, interact synergistically in advanced age. In older adults, hip fractures are a frequent dramatic \"life-transition\" event. Conditions such as arrhythmias, orthostatic hypotension, heart failure, peripheral artery disease and adverse drug reactions may facilitate falls and thus bone fractures in older adults. Cardiovascular complications or the worsening of previous CVDs may increase the degree of frailty and disability following this surgery. The close relationship between older age, CVDs, frailty and orthopaedic surgery leads to the need to focus on the various phases of interventions in a multidisciplinary approach. This document aims to provide practical support to prevent cardiovascular complications in older and frail patients undergoing hip procedures by suggesting specific assessments and interventions. In particular, in pre-operative care the focus should be on the assessment and management of concomitant CVD and frailty, while immediate peri- and post-operative care should highlight specific concerns for anesthesia, prevention and management of thrombotic complications, specific nursing needs, including the prevention of infections and delirium, and the establishment of an integrated rehabilitation program focusing on CVDs and the risk of new falls, with a positive role for care-givers. Furthermore, by optimizing the \"hip surgery pathway\" the objective is to help avoid the deterioration of health and loss of independence that often result from this surgery through the correct management of cardiovascular patients in this peculiar context.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to Letter to the Editor titled, \"Does Evolocumab treatment reduce carotid intima-media thickness in paediatric patients with heterozygous familial hypercholesterolaemia?\" by Christian Saleh.","authors":"Albert Wiegman, Frederick J Raal, Ajay K Bhatia","doi":"10.1093/eurjpc/zwaf005","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf005","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142964295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intervention is Needed in PCOS for Prevention of Cardiovascular Diseases.","authors":"Felice L Gersh, Carl J Lavie, James H O'Keefe","doi":"10.1093/eurjpc/zwaf007","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf007","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142964293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of Heterozygous Familial Hypercholesterolemia in Children: Is Lower Better?","authors":"Vera Bittner","doi":"10.1093/eurjpc/zwaf008","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf008","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142964296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Would a weekly shot be enough to solve the obesity problem? A new denial of a complex reality.","authors":"Alexandre Duparc, Philippe Terral, Olivier Lairez","doi":"10.1093/eurjpc/zwaf002","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf002","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"eSports, exergames, and eAthletes: opportunities and challenges for preventive cardiology on a global scale.","authors":"Erik Fung, Antonio Pelliccia","doi":"10.1093/eurjpc/zwae245","DOIUrl":"10.1093/eurjpc/zwae245","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"88-90"},"PeriodicalIF":8.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicholas A Koemel, Matthew N Ahmadi, Raaj Kishore Biswas, Annemarie Koster, Andrew J Atkin, Angelo Sabag, Emmanuel Stamatakis
{"title":"Can incidental physical activity offset the deleterious associations of sedentary behaviour with major adverse cardiovascular events?","authors":"Nicholas A Koemel, Matthew N Ahmadi, Raaj Kishore Biswas, Annemarie Koster, Andrew J Atkin, Angelo Sabag, Emmanuel Stamatakis","doi":"10.1093/eurjpc/zwae316","DOIUrl":"10.1093/eurjpc/zwae316","url":null,"abstract":"<p><strong>Aims: </strong>Incidental physical activity as part of daily living may offer feasibility advantages over traditional exercise. We examined the joint associations of incidental physical activity and sedentary behaviour with major adverse cardiovascular events (MACE) risk.</p><p><strong>Methods and results: </strong>Analyses included 22 368 non-exercising adults from the UK Biobank accelerometry sub-study (median age [IQR]: 62.9 [11.6] years; 41.8% male). Physical activity and sedentary behaviour exposures were derived using a machine learning-based intensity and posture classification schema. We assessed the tertile-based joint associations of sedentary behaviour and the following: a) incidental vigorous (VPA), b) incidental moderate to vigorous (MVPA), c) vigorous intermittent lifestyle physical activity (VILPA; bouts lasting up to 1 min), and d) moderate to vigorous intermittent lifestyle physical activity (MV-ILPA; bouts lasting up to 3 min) with MACE risk. Over an 8.0-year median follow-up, 819 MACE events occurred. Compared to the highest physical activity and lowest sedentary time, high sedentary behaviour (>11.4 h/day) with low incidental VPA (<2.1 min/day) had an HR of 1.34 (95% CI: 0.98, 1.84) and low incidental MVPA (<21.8 min/day) had a 1.89 HR (95% CI: 1.42, 2.52) for MACE. Sedentary behaviour was not associated with MACE at medium and high levels of VPA or VILPA. Completing 4.1 min/day of VPA or VILPA may offset the MACE risk associated with high sedentary behaviour. Conversely, 31-65 min of incidental MVPA or 26-52 min of MV-ILPA per day largely attenuated the associations with MACE.</p><p><strong>Conclusion: </strong>Brief intermittent bursts of vigorous incidental physical activity may offset cardiovascular risks from high sedentary behaviour.</p><p><strong>Lay summary: </strong>Literature to date has examined the role of total or leisure time physical activity in mitigating the health risks associated with high sedentary behaviour. However, the vast majority of adults achieve their daily physical activity incidentally through day-to-day activities. In this study of 22 368 adults from the UK Biobank accelerometry sub-study, we provide the first investigation into whether a) incidental vigorous (VPA), b) incidental moderate to vigorous (MVPA), c) vigorous intermittent lifestyle physical activity (VILPA; bouts lasting up to 1 min), and d) moderate to vigorous intermittent lifestyle physical activity (MV-ILPA; bouts lasting up to 3 min) completed through normal daily living can offset the risk of major adverse cardiovascular events (MACE) associated with high sedentary behaviour (>11.4 h per day). We demonstrate that incidental VPA and MVPA may offset the MACE risk associated with high-sedentary behaviour even if accrued in brief bursts lasting <3 min. Completing 4.1 min/day of VPA or VILPA may offset the MACE risk associated with high sedentary behaviour.A daily duration of 31-65 min of incidental MVPA or 26-52 min of MV-","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"77-85"},"PeriodicalIF":8.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}