European journal of preventive cardiology最新文献

{"title":"Reply to: Enhancing cardiac rehabilitation: addressing multidimensional aspects of frailty.","authors":"D Scott Kehler, Evan MacEachern, Nicholas Giacomantonio","doi":"10.1093/eurjpc/zwaf200","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf200","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discrepancies Between Office and Home Blood Pressure Targets in Patients with Hypertension According to the 2024 ESC Hypertension Guidelines.","authors":"Rodrigo Bezerra, Audes D M Feitosa, Vanildo S Guimarães-Neto, Alcino P Sá-Filho, Marco A Mota-Gomes, Annelise M G Paiva, Weimar S Barroso, Roberto D Miranda, Eduardo C D Barbosa, Andréa A Brandão, Remo H M Furtado, Luciano F Drager, Antonio Coca, Kazuomi Kario, Andrei C Sposito, Wilson Nadruz","doi":"10.1093/eurjpc/zwaf197","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf197","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time-to-first clinical benefit in heart failure with preserved ejection fraction: A reconstructed time-to-event meta-analysis of randomized controlled trials.","authors":"Christian Basile, Daniele Rodolico, Alessandro Villaschi, Mario Enrico Canonico, Ilaria Fucile, Giuseppe Giugliano, Costantino Mancusi, Carmine Morisco, Giovanni Esposito","doi":"10.1093/eurjpc/zwaf209","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf209","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic status and recurrent cardiovascular events: Preventing the worst or striving for the best?","authors":"Giovanni Civieri, Shady Abohashem","doi":"10.1093/eurjpc/zwaf190","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf190","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Role of Polygenic Risk Scores in Cardiovascular Risk Prediction: A Cross-Sectional Analysis from the Paracelsus 10,000 Cohort.","authors":"Bernhard Wernly, Patrick Langthaler, Barbara Fixl, Tobias Kiesslich, Ludmilla Kedenko, Vanessa Frey, Eugen Trinka, Bernhard Iglseder, Maria Flamm, Elmar Aigner, Bernhard Paulweber","doi":"10.1093/eurjpc/zwaf206","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf206","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality. SCORE2 may underestimate risk in those classified as low-to-moderate risk. Polygenic risk scores (PGS) capture genetic predisposition to CVD and could enhance traditional models. This study examines whether integrating PGS with SCORE2 improves the prediction of significant subclinical coronary atherosclerosis, defined as coronary artery calcium (CAC) >100.</p><p><strong>Methods: </strong>We analyzed data from 1,420 participants in the Paracelsus 10,000 cohort with available PGS, SCORE2, and CAC measurements. Predictive performance was compared across SCORE2 alone, PGS alone, and their combination, assessed using the Akaike Information Criterion (AIC) and area under the receiver operating characteristic curve (AUC). Decision Curve Analysis (DCA) was performed to evaluate clinical utility.</p><p><strong>Results: </strong>PGS improved the prediction of CAC >100 beyond SCORE2 alone, increasing the AUC from 0.662 to 0.738 in women and from 0.659 to 0.714 in men, with substantial Net Reclassification Improvement (NRI: women 0.649, men 0.450). The addition of PGS, particularly in the highest quintiles, significantly enhanced classification accuracy for CAC >100. Decision curve analysis demonstrated that using PGS as a continuous variable provided the highest net benefit at lower threshold probabilities, supporting its role in refining risk stratification, especially in low-to-moderate risk populations.</p><p><strong>Conclusion: </strong>PGS enhances SCORE2-based prediction of significant CAC. These findings highlight the potential of PGS to refine cardiovascular risk stratification, supporting targeted screening and prevention. Prospective validation, assessment of long-term cardiovascular outcomes, and cost-effectiveness analysis are warranted to guide clinical implementation.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sudden Arrhythmic Death Syndrome: Are We Missing the Clues in Women?","authors":"Orianne Weizman, Bo Gregers Winkel, Eloi Marijon","doi":"10.1093/eurjpc/zwaf215","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf215","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inconsistent Association Between Lipoprotein(a) and Coronary Artery Calcium.","authors":"Alexander C Razavi, Michael J Blaha, Harpreet S Bhatia","doi":"10.1093/eurjpc/zwaf196","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf196","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of ideal cardiovascular health and Life's Simple 7 metrics with incident heart failure among older men: the British Regional Heart Study.","authors":"Mehar Chawla, Olia Papacosta, Lucy Lennon, Ayesha Ahmed, Peter Whincup, S Goya Wannamethee","doi":"10.1093/eurjpc/zwaf216","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf216","url":null,"abstract":"<p><strong>Background: </strong>Ideal cardiovascular health (CVH) determined by categorisation of component Life's Simple 7 (LS7) metrics has been associated with reduced risk of heart failure (HF). However, few studies have explored the relationship between changes in CVH from middle to older age and HF incidence.</p><p><strong>Aims: </strong>We aim to investigate the association between LS7 metrics and their impact on HF incidence in older men. Additionally, we explore whether changes in CVH scores between middle and older age were associated with subsequent HF risk.</p><p><strong>Methods: </strong>The British Regional Heart Study is a prospective study of 7735 men, aged 40-59y at enrolment (1978-1980) from 24 British towns. Information on LS7 metrics was gathered at initial recruitment and again at re-examination 20y later. Follow-up for HF was conducted from re-examination onwards.</p><p><strong>Results: </strong>Among 3698 men (60-79y) without prior myocardial infarction or HF, 369 developed HF during a median follow-up of 15.8y. Ideal CVH was associated with significantly lower risk of HF relative to poor CVH after adjusting for age, social class and alcohol intake (HR 95%CI = 0.51 0.38-0.68). Men who maintained high CVH scores between baseline and 20y re-examination (high-high group) showed a significant 33% reduction in risk of HF (HR 95%CI= 0.67 0.51-0.87) compared to those with consistently low CVH scores. These associations persisted after adjustment for competing mortality.</p><p><strong>Conclusions: </strong>Our results highlight that a consistently healthy lifestyle, as reflected in a better CVH score maintained over an adult lifetime, is associated with lower HF risk in older men.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Living Close to Risk: Disentangling Associations of the Residential Exposome and Socioeconomic Disparities with Coronary Artery Disease.","authors":"Geyner Andres Gaona, Shady Abohashem, Seth S Martin","doi":"10.1093/eurjpc/zwaf199","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf199","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intensive systolic blood pressure control in patients with or without worsening renal function.","authors":"Xiaoli Xu, Xiaoyun Zhang, Siyu Wang, Kan Wang, Yu Xiang, Yuanyue Zhu, Xuan Zhao, Yueyue Wang, Xi Meng, Zhiyun Zhao, Tiange Wang, Jie Zheng, Min Xu, Jieli Lu, Mian Li, Weiqing Wang, Guang Ning, Yufang Bi, Yu Xu","doi":"10.1093/eurjpc/zwaf184","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf184","url":null,"abstract":"<p><strong>Aims: </strong>Intensive systolic blood pressure (BP) control is associated with a lower risk of cardiovascular disease (CVD) but an increased risk of worsening renal function (WRF). This study aimed to investigate whether intensive BP control should be continued after WRF.</p><p><strong>Methods: </strong>We performed a post hoc analysis of SPRINT (Systolic Blood Pressure Intervention Trial). WRF was defined as an eGFR decline of ≥30% during follow-up from baseline. The associations between WRF, efficacy and safety outcomes, and BP treatment were evaluated using time updated Cox proportional hazard models.</p><p><strong>Results: </strong>Among 9,211 participants included in this analysis, 1,310 participants (14.2%) experienced WRF during follow-up. The intensive BP treatment significantly reduced the risk of the primary outcome compared with the standard BP treatment among patients with WRF (HR: 0.54; 95% CI: 0.32-0.90) and without WRF (HR: 0.82; 95% CI: 0.68-0.98; P  interaction = 0.224). In addition, the intensive BP treatment significantly reduced the risk of all-cause death among patients with WRF (HR: 0.40; 95% CI: 0.23-0.68), but not among patients without WRF (HR: 0.84; 95% CI: 0.67-1.07; P  interaction = 0.046). Risks of safety events were similar between BP treatment groups among patients with and without WRF. Results were similar among participants who experienced WRF early or late during the intervention.</p><p><strong>Conclusion: </strong>Intensive BP treatment increased the risk of WRF compared with standard BP treatment. However, intensive BP treatment was associated with reduced risks of CVD and all-cause mortality compared with standard BP treatment in patients experiencing WRF, without increasing adverse events.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}