European journal of preventive cardiology最新文献

{"title":"Diabetes and cardiovascular risk: the ever-evolving scenario.","authors":"Remya Sudevan, Matthew Allison","doi":"10.1093/eurjpc/zwae266","DOIUrl":"10.1093/eurjpc/zwae266","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"384-385"},"PeriodicalIF":8.4,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in the association of lifestyle-related modifiable risk factors with incident cardiovascular disease between individuals with and without diabetes.","authors":"Kaoruko Komuro, Hidehiro Kaneko, Jin Komuro, Yuta Suzuki, Akira Okada, Atsushi Mizuno, Katsuhito Fujiu, Norifumi Takeda, Hiroyuki Morita, Koichi Node, Hideo Yasunaga, Norihiko Takeda, Masaki Ieda, Issei Komuro","doi":"10.1093/eurjpc/zwae221","DOIUrl":"10.1093/eurjpc/zwae221","url":null,"abstract":"<p><strong>Aims: </strong>Individuals with diabetes have a high risk of developing cardiovascular disease (CVD). Little was known whether the association between modifiable risk factors and incident CVD would change according to the presence of diabetes.</p><p><strong>Methods and results: </strong>In this study, we analysed 4 132 006 individuals including 173 262 individuals (4.2%) with diabetes registered in the JMDC Claims Database, and compared the association between modifiable risk factors and risk of CVD between individuals with and without diabetes. The median age was 44 years, and 57.5% were men. Multivariable Cox regression analyses showed that the relationship of obesity, hypertension, and dyslipidaemia with incident CVD was attenuated in individuals with diabetes, whereas that of non-ideal eating habits, smoking, and physical inactivity with incident CVD was pronounced in those with diabetes. The hazard ratio per 1-point increase in non-ideal lifestyle-related factors was 1.03 [95% confidence interval (CI), 1.03-1.04] in individuals with non-diabetes, whereas 1.09 (95% CI, 1.07-1.11) in individuals with diabetes (P-value for interaction < 0.001). Further, hazard ratios for developing CVD were 1.02 (95% CI, 1.01-1.04) in individuals not having diabetes, whereas 1.09 (95% CI, 1.04-1.13) in individuals having diabetes for the increase of lifestyle-related factors after 1-year follow-up (P-value for interaction 0.007).</p><p><strong>Conclusion: </strong>Our analysis utilizing a nationwide epidemiological dataset presented that the relationship of lifestyle-related factors with incident CVD would be pronounced in people having diabetes, suggesting that the maintenance of a healthy lifestyle would play a more important role in the development of CVD in individuals having diabetes.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"376-383"},"PeriodicalIF":8.4,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141467143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The capital importance of lifestyle and diet in cardiovascular disease prevention.","authors":"Marjan Walli-Attaei, Victor Aboyans","doi":"10.1093/eurjpc/zwaf131","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf131","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":"32 5","pages":"355-357"},"PeriodicalIF":8.4,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association and predictive value of immunoglobulin and complement levels for incident coronary heart disease: a nested case-control study in Chinese adults.","authors":"Qin Jiang, Rundong Niu, Jing Jiang, Hanyu Hu, Shiqi He, Hao Wang, Yu Yuan, Handong Yang, Chengwei Xu, Xiaomin Zhang, Meian He, Huan Guo, Xiang Cheng, Chaolong Wang, Tangchun Wu, Pinpin Long","doi":"10.1093/eurjpc/zwaf091","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf091","url":null,"abstract":"<p><strong>Aims: </strong>To investigate the associations of serum immunoglobulin (Ig) and complement levels with incident coronary heart disease (CHD), and to explore the potential mediating role of C-reactive protein (CRP).</p><p><strong>Methods and results: </strong>We measured serum levels of IgA, IgE, IgG, IgM, complement 3 (C3), complement 4 (C4), and CRP in a nested case-control study within the Dongfeng-Tongji cohort, consisting of 1605 CHD cases and 1605 age- and sex-matched controls. We quantified the associations of serum Ig and complement levels with incident CHD using conditional logistic regression and restricted cubic spline models. Mediation analysis was conducted to explore the role of CRP in these associations. The additional predictive ability of an immune indicator score beyond traditional risk factors was also evaluated. Higher IgA and C3 levels were associated with an increased risk of CHD in a linear manner [odds ratio (OR) (95% confidence interval, CI): 1.35 (1.11-1.62), P = 0.002; OR (95% CI): 2.01 (1.17-3.44), P = 0.01, respectively]. Conversely, higher IgG exhibited a significant linear decrease in CHD risk [OR (95% CI): 0.55 (0.36-0.83), P = 0.005]. C-reactive protein mediated 5.70% and 12.51% in the associations of IgA and C3 with incident CHD, respectively. Adding an immune indicator score to the traditional risk model improved CHD prediction more effectively than adding CRP [area under receiver operating characteristic curve (AUC): 0.85% vs. 0.21%; net reclassification improvement (NRI): 15.33% vs. 7.85%; integrated discrimination improvement (IDI): 0.80% vs. 0.17%].</p><p><strong>Conclusion: </strong>Our study identified IgA and C3 as independent risk factors and IgG as a protective factor for CHD. These immune markers may improve CHD risk prediction beyond traditional and CRP models, highlighting their potential for better risk assessment.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Should we favour organic foods over non-organic products in cardiovascular disease prevention?","authors":"Anat Yaskolka Meir, Yutao Guo","doi":"10.1093/eurjpc/zwaf125","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf125","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Cardiovascular Disease Journals in Reporting Sex and Gender in Research.","authors":"C Noel Bairey Merz, Robert O Bonow, Mercedes Carnethon, Filippo Crea, Joseph A Hill, Harlan M Krumholz, Roxana Mehran, Erica S Spatz","doi":"10.1093/eurjpc/zwaf160","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf160","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occasional smoking is a risk factor for myocardial infarction in the population-based Tromsø Study, 2001-2021.","authors":"Sweta Tiwari, Ola Løvsletten, Bjarne K Jacobsen, Tom Wilsgaard, Ellisiv B Mathiesen, Henrik Schirmer, Inger T Gram, Jan Mannsverk, Maja-Lisa Løchen","doi":"10.1093/eurjpc/zwaf182","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf182","url":null,"abstract":"<p><strong>Aims: </strong>While the association between daily smoking and myocardial infarction (MI) risk is well-established, little is known concerning the relationship between occasional smoking and MI risk. In this Norwegian study, we aimed to investigate the risk of first-time MI among occasional smokers over a 20-year follow-up period.</p><p><strong>Methods: </strong>In this prospective cohort study, data on smoking habits and relevant risk factors were collected from 15,617 participants enrolled in the fifth and/or sixth survey of the Tromsø Study. Participants were followed up for the first MI from 2001 to 2021. Smoking, age, marriage/cohabitant status, body mass index, hypertension, cholesterol, alcohol consumption, education, physical activity and sex were included as covariates in Cox proportional hazard models.</p><p><strong>Results: </strong>At baseline, 9.2% participants were occasional smokers. Over the follow-up period, 1297 participants experienced their first MI. Adjusted for covariates, we observed a 41% increased MI risk among occasional smokers compared to never smokers (hazard ratio (HR) 1.41, 95% confidence interval (CI) 1.11 to 1.80). We noted a dose-response relationship in the hazards of smoking, categorized as never, former, occasional, and daily. Compared with never smokers, the relative risk of MI in occasional smokers was twice as high in women (HR 2.08, 95% CI 1.43 to 3.04) and 11% higher in men (HR 1.11, 95% CI 0.81 to 1.52).</p><p><strong>Conclusion: </strong>This study highlights an elevated risk of MI among occasional smokers, with higher relative risk in women. The result emphasizes that there is no safe threshold for smoking, underlining the importance of smoking cessation.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular Risk Assessment in Male and Female Patients With and Without Depression: an Electronic Health Record Evaluation in Wales.","authors":"Elizabeth A Ellins, Richard Summers, Ann John, David Pj Osborn, Keith Lloyd, Ashley Akbari, Michael B Gravenor, Julian P Halcox","doi":"10.1093/eurjpc/zwaf178","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf178","url":null,"abstract":"<p><strong>Aim: </strong>To investigate rates of cardiovascular risk factor assessment (blood pressure, lipid and QRISK score) in routine clinical practice for primary prevention of cardiovascular disease (CVD) in patients with and without depression.</p><p><strong>Methods: </strong>A retrospective observational cohort study using electronic health record data sources was carried out. Rates of blood pressure measurement, lipid checks and QRISK documentation in primary care were calculated for non-depressed, and patients prior and subsequent to depression diagnosis. Poisson regression adjusting for age and sex was used to explore associations between depression status and rate of assessment. Differences in rates of assessment by deprivation and location of residence (urban/rural) were also explored.</p><p><strong>Results: </strong>Of 2,290,075 patients, 176,062 had depression diagnosed. Patients with depression had blood pressure and lipid levels checked and QRISK score documented more frequently, after adjustment for sex and age group. Sex differences were noted, with younger females more likely to have blood pressure assessment and males more likely to have lipid levels checked, irrespective of depression status. There were significant three-way interactions between depression*sex*age group for all outcomes, with sex difference in blood pressure assessment highly dependent on age, and sex/depression status difference in lipid assessment most notable in the 60-74 age group.</p><p><strong>Conclusion: </strong>Patients with depression are more likely to have their blood pressure, lipid levels and QRISK documented than patients without depression. Sex differences in assessment of blood pressure and lipid assessments may also impact on future cardiovascular risk management, providing opportunities for potential improvements in assessment of risk factors.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Z-drugs are associated with cardiovascular outcomes among patients with heart failure: a population-based cohort study in Hong Kong.","authors":"Hai-Yue Yang, Qing-Wen Ren, An-Ping Cai, Jia-Yi Huang, Ran Guo, Wen-Li Gu, Jing-Nan Zhang, Xin-Li Li, Ren-Qiang Yang, Kai-Hang Yiu","doi":"10.1093/eurjpc/zwaf128","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf128","url":null,"abstract":"<p><strong>Aims: </strong>Patients with heart failure (HF) often suffered from concomitant insomnia. Non-benzodiazepine GABA receptor agonists (Z-drugs) are hypnotics commonly used for treating insomnia. The effect of Z-drugs on the outcomes of patients with HF is nonetheless sparse. Our study aims to investigate the association of Z-drugs and the risks of adverse cardiovascular outcomes in the HF population.</p><p><strong>Methods and results: </strong>A total of 202 585 patients (mean age 73.24, 47.8% male) diagnosed with HF between 2001 and 2020 were identified from Hong Kong Clinical Data Analysis Reporting System. Propensity score matching and competing risk regression with Cox proportional hazard models were performed to evaluate the use of Z-drugs (n = 14 765, 7.3%) and the risks of primary composite endpoint of HF rehospitalization and cardiovascular death (CVD), HF rehospitalization, CVD, and all-cause mortality. Over a median follow-up of 10.5 years (interquartile range 5.7-15.8 years), use of Z-drugs was correlated with 21% higher risk of primary composite endpoint [multivariable adjusted sub-distribution hazard ratio (SHR): 1.21, 95% confidence interval (CI): 1.18-1.24], 21% higher risk of HF rehospitalization (SHR: 1.21, 95% CI: 1.17-1.24), 11% higher risk of CVD (SHR: 1.11, 95% CI: 1.07-1.15), and 15% higher risk of all-cause mortality (HR: 1.15, 95% CI: 1.11-1.18). A duration-dependent relationship was also observed, with worse outcomes seen in long-term use compared with short-term use.</p><p><strong>Conclusion: </strong>Our findings suggest that the use of Z-drugs increases the risks of adverse cardiovascular outcomes among patients with HF.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary dicarbonyl compounds: independently cardioprotective or beneficial by association?","authors":"Nicole J Kellow","doi":"10.1093/eurjpc/zwaf179","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf179","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}