European journal of preventive cardiology最新文献

{"title":"Every activity at any intensity counts in cardiovascular prevention in individuals with cardiovascular disease.","authors":"Esmée A Bakker, Henner Hanssen","doi":"10.1093/eurjpc/zwae299","DOIUrl":"10.1093/eurjpc/zwae299","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"30-31"},"PeriodicalIF":8.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EJPC @ a glance: focus issue on intensity and personalization in physical activity for cardiovascular prevention.","authors":"Louis-Marie Desroche, Victor Aboyans","doi":"10.1093/eurjpc/zwae381","DOIUrl":"https://doi.org/10.1093/eurjpc/zwae381","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":"32 1","pages":"7-9"},"PeriodicalIF":8.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intensity or volume: the role of physical activity in longevity.","authors":"Fabian Schwendinger, Denis Infanger, Eric Lichtenstein, Timo Hinrichs, Raphael Knaier, Alex V Rowlands, Arno Schmidt-Trucksäss","doi":"10.1093/eurjpc/zwae295","DOIUrl":"10.1093/eurjpc/zwae295","url":null,"abstract":"<p><strong>Aims: </strong>To investigate how physical activity (PA) volume, intensity, duration, and fragmentation are associated with the risk of all-cause and cardiovascular disease mortality. To produce centile curves for PA volume and intensity representative of US adults.</p><p><strong>Methods and results: </strong>This study is based on the observational 2011-2014 National Health and Nutrition Examination Survey (NHANES). Adults (age, ≥20) with valid accelerometer, covariate, and mortality data were included. Average acceleration (AvAcc), intensity gradient (IG), and total PA served as proxies for volume, intensity, and duration of PA, respectively. Weighted Cox proportional hazard models estimated associations between outcome and PA metrics. In 7518 participants (52.0% women, weighted median age of 49), there were curvilinear inverse dose-response relationships of all-cause mortality risk (81-month follow-up) with both AvAcc [-14.4% (95% CI, -8.3 to -20.1%) risk reduction from 25th to 50th percentile] and IG [-37.1% (95% CI, -30.0 to -43.4%) risk reduction from 25th to 50th percentile], but for cardiovascular disease (CVD) mortality risk (n = 7016, 82-month follow-up) only with IG [-41.0% (95% CI, -26.7 to -52.4%) risk reduction from the 25th to 50th percentile]. These relationships plateau at AvAcc: ∼35-45 mg and IG: -2.7 to -2.5. Associations of PA with all-cause and cardiovascular disease mortality are primarily driven by intensity and secondary by volume. Centile curves for volume and intensity were generated.</p><p><strong>Conclusion: </strong>Intensity is a main driver of reduced mortality risk suggesting that the intensity of PA rather than the quantity matters for longevity. The centile curves offer guidance for achieving desirable PA levels for longevity.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"10-19"},"PeriodicalIF":8.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Cardiac rehabilitation registries around the globe: current status and future needs.","authors":"","doi":"10.1093/eurjpc/zwae397","DOIUrl":"https://doi.org/10.1093/eurjpc/zwae397","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Obesity and cardiovascular disease: an ESC clinical consensus statement.","authors":"","doi":"10.1093/eurjpc/zwae398","DOIUrl":"https://doi.org/10.1093/eurjpc/zwae398","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intensive screening for atrial fibrillation may not prevent recurrent stroke: a review of the current guidelines.","authors":"Thomas A Slater, Muzahir H Tayebjee","doi":"10.1093/eurjpc/zwad302","DOIUrl":"10.1093/eurjpc/zwad302","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"e127-e128"},"PeriodicalIF":8.4,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10321868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A randomized controlled implementation study integrating patient self-screening with a remote central monitoring system to screen community dwellers aged 75 years and older for atrial fibrillation.","authors":"Kam Cheong Wong, Tu N Nguyen, Simone Marschner, Samual Turnbull, Anupama Balasuriya Indrawansa, Rose White, Mason Jenner Burns, Vishal Gopal, Haeri Min, Desi Quintans, Amy von Huben, Steven A Trankle, Tim Usherwood, Richard I Lindley, Saurabh Kumar, Clara K Chow","doi":"10.1093/eurjpc/zwae312","DOIUrl":"10.1093/eurjpc/zwae312","url":null,"abstract":"<p><strong>Aims: </strong>Diagnosis of atrial fibrillation (AF) provides opportunities to reduce stroke risk. This study aimed to compare AF diagnosis rates, participant satisfaction, and feasibility of an electrocardiogram (ECG) self-screening virtual care system with usual care.</p><p><strong>Methods and results: </strong>This randomized controlled implementation study involving community-dwelling people aged ≥75 years was conducted from May 2021 to June 2023. Participants were given a handheld single-lead ECG device and trained to self-record ECGs once daily on weekdays for 12 months. The control group received usual care with their general practitioners in the first 6 months and participated in the subsequent 6 months. Atrial fibrillation diagnosis and participant satisfaction were assessed at 6 months. Two hundred participants (mean age 79.0 ± 3.4 years; 54.0% female; 72.5% urban) were enrolled. Atrial fibrillation was diagnosed in 10/97 (10.3%) intervention participants and 2/100 (2.0%) in the control group (odds ratio 5.6, 95% confidence interval 1.4-37.3, P = 0.03). In the intervention, 80% of AF cases were diagnosed within 3 months. 91/93 (97.9%) intervention participants and 55/93 (59.1%) control-waitlisted participants (P < 0.001) were satisfied with AF screening. Of the expected 20 days per month, the overall monthly median number of days participants self-recorded ECGs was 20 (interquartile range 17-22). Participants were confident using the device (93%), reported it was easy to use (98%), and found screening efficient (96%).</p><p><strong>Conclusion: </strong>Patient-led AF self-screening using single-lead ECG devices with a remote central monitoring system was feasible, acceptable, and effective in diagnosing AF among older people. This screening model could be adapted for implementation, interfacing with integrated care models within existing health systems.</p><p><strong>Registration: </strong>Australian New Zealand Clinical Trials Registry identifier: ACTRN12621000184875.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"2104-2114"},"PeriodicalIF":8.4,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenotypic characterization of people at risk of atrial fibrillation: protocol for the FIND-AF longitudinal cohort study.","authors":"Ali Wahab, Ramesh Nadarajah, Catherine Reynolds, Sheena Bennett, Edisemi Ambakederemo, Mohammad Harris, Tanina Younsi, Tobin Joseph, Keerthenan Raveendra, Adam Smith, Asad Bhatty, Gregory Y H Lip, Peter P Swoboda, Jianhua Wu, Chris P Gale","doi":"10.1093/eurjpc/zwae303","DOIUrl":"10.1093/eurjpc/zwae303","url":null,"abstract":"<p><strong>Aims: </strong>The Future Innovations in Novel Detection of Atrial Fibrillation (FIND-AF) longitudinal cohort study is a multi-centre prospective cohort study of patients identified at risk of atrial fibrillation (AF). The aim of the FIND-AF longitudinal cohort study is to provide multi-modal phenotypic characterization of these patients.</p><p><strong>Methods and results: </strong>A total of 1955 participants identified as at risk of AF by the FIND-AF algorithm from primary care electronic health record (EHR) data, aged 30 years and above and eligible for oral anticoagulation, will be recruited between October 2023 and November 2024 to receive home-based intermittent electrocardiogram monitoring. About 500 participants without diagnosed AF will then undergo cross-sectional phenotypic characterization including physical examination, symptoms assessment, serum blood biomarkers and echocardiography, and non-stress cardiac magnetic resonance imaging. Longitudinal information about cardio-renal-metabolic-pulmonary outcomes will be ascertained from linkages to EHR data. The study is funded by the British Heart Foundation (CC/22/250026). The study has ethical approval (North West-Greater Manchester South Research Ethics Committee reference 23/NW/0180). Findings will be announced at relevant conferences and published in peer-reviewed journals in line with the funder's open-access policy.</p><p><strong>Conclusion: </strong>The FIND-AF multi-centre prospective longitudinal cohort study aims to (i) provide evidence for the impact of comorbidities on AF genesis, (ii) uncover actionable targets to prevent AF, and (iii) act as a platform for cohort randomized clinical trials that investigate enhanced detection and prevention of AF.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"2099-2103"},"PeriodicalIF":8.4,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smoking timing, genetic susceptibility, and the risk of incident atrial fibrillation: a large prospective cohort study.","authors":"Jian Zhou, Ying Hu, Rui Tang, Minghao Kou, Xuan Wang, Hao Ma, Xiang Li, Yoriko Heianza, Lu Qi","doi":"10.1093/eurjpc/zwae270","DOIUrl":"10.1093/eurjpc/zwae270","url":null,"abstract":"<p><strong>Aims: </strong>Although smoking is a well-known risk factor for atrial fibrillation (AF), the association of smoking timing with AF risk remains unclear. This study aimed to prospectively investigate the association of smoking timing with the risk of incident AF and test the modification effect of genetic susceptibility.</p><p><strong>Methods and results: </strong>A total of 305 627 participants with detailed information for time from waking to the first cigarette were enrolled from UK Biobank database. The Cox proportional hazard model was employed to assess the relationship between smoking timing and AF risk. The weighted genetic risk score for AF was calculated. Over a median 12.2-year follow-up, 13 410 AF cases were documented. Compared with non-smokers, time from waking to the first cigarette showed gradient inverse associations with the risk of incident AF (P-trend <0.001). The adjusted hazard ratio related to smoking timing was 1.13 [95% confidence interval (CI): 0.96-1.34] for >120 min, 1.20 (95% CI: 1.01-1.42) for 61-120 min, 1.34 (95% CI: 1.19-1.51) for 30-60 min, 1.43 (95% CI: 1.26-1.63) for 5-15 min, and 1.49 (95% CI: 1.24-1.63) for <5 min, respectively. Additionally, we found that the increased risk of AF related to shorter time from waking to the first cigarette was strengthened by the genetic susceptibility to AF.</p><p><strong>Conclusion: </strong>Our findings suggest gradient inverse association between time from waking to the first cigarette and risk of incident AF, and the association is strengthened by the genetic susceptibility to AF.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":"2086-2096"},"PeriodicalIF":8.4,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142043891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of age and sex on the diagnostic yield of inherited cardiac conditions in sudden arrhythmic death syndrome decedents.","authors":"Belinda Gray, Elijah R Behr, Efstathios Papatheodorou, Athanasios Bakalakos, Hariharan Raju, Yanushi D Wijeyeratne, Gherardo Finocchiaro, Aneil Malhotra, Nicola Whiffin, James S Ware, Maria Tome Esteban, Mary N Sheppard, Sanjay Sharma, Michael Papadakis","doi":"10.1093/eurjpc/zwae389","DOIUrl":"https://doi.org/10.1093/eurjpc/zwae389","url":null,"abstract":"<p><strong>Aims: </strong>Sudden arrhythmic death syndrome (SADS) refers to a sudden death, which remains unexplained despite comprehensive post-mortem examination and a toxicological screen. We aimed to investigate the impact of age and sex on the overall diagnostic yield and underlying aetiology in decedents with SADS using a combined approach of familial evaluation (FE) and molecular autopsy (MA).</p><p><strong>Methods and results: </strong>Consecutive referrals to a single centre for FE only, MA only or both, following a SADS death were included. First-degree family members underwent comprehensive FE and decedents with post-mortem DNA were sequenced with a 36 cardiac gene panel for MA. A Bayesian framework for analysis was performed to identify associations. Among 760 SADS decedents (66% male; mean age 31 ± 12 years) the overall diagnostic yield for an inherited cardiac condition was 37% (32-42%) and 9% (6-12%) for FE and MA cohorts. In a subset where both FE and MA were performed the diagnostic yield was 45% (38-61%). The relative risk of an FE diagnosis of long QT syndrome (LQTS) or Catecholaminergic polymorphic ventricular tachycardia (CPVT) vs. remaining unexplained declined by 5.6% [RR 0.94 (0.91-0.98)] and by 11% [RR 0.89 (0.81-0.97)], for each year increase in age. Females were more likely to have a diagnosis by both FE [40% (34-45%) vs. 36% (31-41%)] and MA [15% (10-21%) vs. 6% (3-8%)]. Females [8.1% (4.1-13.4%)], were more likely to be diagnosed with LQTS than males [1.2% (0.2-2.7%)] in the MA cohort.</p><p><strong>Conclusion: </strong>After a SADS death, the diagnostic yield of comprehensive FE, MA, or both in an expert setting can be up to 45% with a combined approach. Females had higher diagnostic yield than males, most notable with LQTS. CPVT and LQTS diagnoses declined with increasing age. These data highlight the relative utility of FE and MA depending on age and sex for determining underlying diagnoses following SADS deaths.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}