{"title":"Correction to: Systematic Coronary Risk Evaluation 2 for Older Persons: 10 years risk validation, clinical utility, and potential improvement.","authors":"","doi":"10.1093/eurjpc/zwaf172","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf172","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143729544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"All in the family: A referral strategy for screening relatives of individuals with premature coronary artery disease.","authors":"Josh Solomon, Michael Goldfarb","doi":"10.1093/eurjpc/zwaf181","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf181","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Panos E Vardas, Emmanouil P Vardas, Lampros K Michalis
{"title":"Leveraging Deep Learning for Urban Health Insights: Transforming Street-Level Imagery into Cardiovascular Risk Indicators.","authors":"Panos E Vardas, Emmanouil P Vardas, Lampros K Michalis","doi":"10.1093/eurjpc/zwaf148","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf148","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Serenella Castelvecchio, Rossella Nappi, Lucia Ramputi, Rosanna Cardani, Daniela Mazzaccaro, Guendalina Graffigna, Sara Boveri, Valentina Milani, Irene Baroni, Arianna Magon, Gianluca Conte, Manuel B Trevisan, Ambra Cerri, Giada De Angeli, Giulia Paglione, Massimo Piepoli, Lorenzo Menicanti, Rosario Caruso
{"title":"Different patterns of lifestyles, socio-demography, clinical patterns, and cardiovascular health awareness among women. Results from the \"Call for Women\" population-based survey.","authors":"Serenella Castelvecchio, Rossella Nappi, Lucia Ramputi, Rosanna Cardani, Daniela Mazzaccaro, Guendalina Graffigna, Sara Boveri, Valentina Milani, Irene Baroni, Arianna Magon, Gianluca Conte, Manuel B Trevisan, Ambra Cerri, Giada De Angeli, Giulia Paglione, Massimo Piepoli, Lorenzo Menicanti, Rosario Caruso","doi":"10.1093/eurjpc/zwaf174","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf174","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Remnant cholesterol, inflammation and atherosclerosis.","authors":"Liam R Brunham","doi":"10.1093/eurjpc/zwaf098","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf098","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolle Kränkel, Aycen Koc, Bita Astan, Sabine Kaczmarek, Kristin Lehnert, Anke Hannemann, Nele Friedrich, Kathrin Budde, Ann-Kristin Henning, Grazyna Domanska, Arash Haghikia, Stefan Gross, Christian Templin, Ulf Landmesser, Stephan B Felix, Marcus Dörr, Martin Bahls
{"title":"Immune-metabolic response to acute exercise in patients with heart failure with reduced ejection fraction.","authors":"Nicolle Kränkel, Aycen Koc, Bita Astan, Sabine Kaczmarek, Kristin Lehnert, Anke Hannemann, Nele Friedrich, Kathrin Budde, Ann-Kristin Henning, Grazyna Domanska, Arash Haghikia, Stefan Gross, Christian Templin, Ulf Landmesser, Stephan B Felix, Marcus Dörr, Martin Bahls","doi":"10.1093/eurjpc/zwaf171","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf171","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vasiliki Lagou, Arno Greyling, Mario Ferruzzi, Simon S Skene, Joy Dubost, Ayse Demirkan, Inga Prokopenko, Julie Shlisky, Ana Rodriguez-Mateos, Christian Heiss
{"title":"Impact of flavan-3-ols on blood pressure and endothelial function in diverse populations: a systematic review and meta-analysis of randomised controlled trials.","authors":"Vasiliki Lagou, Arno Greyling, Mario Ferruzzi, Simon S Skene, Joy Dubost, Ayse Demirkan, Inga Prokopenko, Julie Shlisky, Ana Rodriguez-Mateos, Christian Heiss","doi":"10.1093/eurjpc/zwaf173","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf173","url":null,"abstract":"<p><strong>Background and aims: </strong>Flavan-3-ols, found in cocoa, tea, and certain fruits, show promise in improving blood pressure (BP) and vascular function, but are currently not used for cardiovascular prevention. This meta-analysis evaluated the effects of flavan-3-ol-rich interventions on BP and endothelial function.</p><p><strong>Methods: </strong>PubMed was searched for randomized controlled trials (RCTs) published 1946-03/2024 on BP and flow-mediated dilation (FMD) after flavan-3-ol-rich food, beverage, or supplement intake. Random-effects meta-analysis of 109 publications including 145 RCTs and 5,205 participants was performed. (PROSPERO:CRD42023454691).</p><p><strong>Results: </strong>Flavan-3-ol interventions included epicatechin, epigallocatechin-gallate, cocoa products, tea, grape extract, and apples delivering 586 mg (95%CI 510,662) total flavan-3-ols. Interventions decreased office (-2.8 [95%CI -3.9, -1.7]/-2.0 [-2.6, -1.3] mmHg) and 24h-ambulatory BP (-3.7 [-5.8, -1.6]/-2.6 [-4.5, -0.8] mmHg) after chronic repetitive consumption. Effects were larger with elevated and hypertensive baseline BP or categorical hypertension (office: -5.9 [-10.0, -1.8]/-2.7 [-4.4, -1.0] mmHg, 24h-ABP: -6.8 [-16.3,2.8]/-5.1 [-12.5,2.2] mmHg). Meta-regression analysis confirmed that the magnitude of BP lowering was inversely related to baseline BP, but not to proportion of participants with CVD, diabetes mellitus, and study duration across all studies, and was dose-dependently related to epicatechin dose only in cocoa studies. FMD increased after acute (+2.0% [1.6,2.3]) and repetitive (+1.7% [1.3,2.2]) consumption independent of BP. Reported adverse events were minor and low (0.4%). The considerable heterogeneity of effect sizes (I2>50%) between studies was not explained by the investigated factors limiting the strength of evidence to 'moderate'.</p><p><strong>Conclusions: </strong>Flavan-3-ol-rich foods considerably reduce elevated BP and improve endothelial function independent of blood pressure supporting their use for cardiovascular prevention.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jung-Kyu Han, Kyungdo Han, You-Jeong Ki, Jin-Eun Song, Doyeon Hwang, Jeehoon Kang, Han-Mo Yang, Kyung Woo Park, Hyun-Jae Kang, Bon-Kwon Koo, Hyo-Soo Kim
{"title":"Aerobic Exercise and Cardiovascular Outcomes in Patients with Diabetes Undergoing Percutaneous Coronary Intervention: A Nationwide Population-based Study.","authors":"Jung-Kyu Han, Kyungdo Han, You-Jeong Ki, Jin-Eun Song, Doyeon Hwang, Jeehoon Kang, Han-Mo Yang, Kyung Woo Park, Hyun-Jae Kang, Bon-Kwon Koo, Hyo-Soo Kim","doi":"10.1093/eurjpc/zwaf170","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf170","url":null,"abstract":"<p><strong>Aims: </strong>We investigated the impact of aerobic exercise on clinical outcomes in patients with diabetes undergoing percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>We analyzed a nationwide prospective population database from the Korean National Health Insurance System. We included 8,225 patients with diabetes who had undergone PCI and documented their aerobic exercise habits before and after the procedure (mean interval: 2.0 years). The patients were categorized into four groups: persistent non-exercisers, new exercisers, exercise discontinuers, and exercise maintainers. The primary outcome was major adverse cardiovascular events (MACE), a composite of all-cause death, myocardial infarction, revascularization, and heart failure. We assessed the risk of clinical events using inverse probability-weighted Cox proportional hazards models.</p><p><strong>Results: </strong>During a mean follow-up of 4.9 years, exercise maintainers, discontinuers, and new exercisers were associated with a significantly lower risk of MACE compared to non-exercisers. The lowest risk was observed in exercise maintainers (maintainers: aHR, 0.78; 95%CI, 0.71-0.86; discontinuers: aHR, 0.88; 95%CI, 0.79-0.98; new exercisers: aHR 0.89; 95%CI, 0.80-1.00). A J-curve relationship between the amount of aerobic exercise and adverse clinical outcomes was observed, with the lowest risk identified at 1,000-1,499 MET-min/week. Benefits diminished with exercise intensity ≥1500 MET-min/week.</p><p><strong>Conclusion: </strong>Aerobic exercise maintenance after PCI was associated with a reduced risk of cardiovascular events in patients with diabetes, with a moderate amount of exercise providing maximal benefit. Therefore, aerobic exercise is advisable for patients with diabetes undergoing PCI, and the optimal exercise dosage warrants further research.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exercise in carriers of truncated Titin variants: more evidence before the greenlight.","authors":"K M Karaye, K Sliwa","doi":"10.1093/eurjpc/zwaf161","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf161","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}