European journal of preventive cardiology最新文献_第3页

Clarifying the Cognitive Mechanisms and Isolated Effects of Plaque Visualization in Cardiovascular Risk Reduction. 阐明斑块可视化在心血管风险降低中的认知机制和孤立效应。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-06-26 DOI: 10.1093/eurjpc/zwaf382

Abudula Aierken, Qian Zhao, Yasong Xiao

引用次数: 0

BMI during childhood and puberty - associations with blood pressure and hypertension. 儿童和青春期的身体质量指数——与血压和高血压的关系。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-06-25 DOI: 10.1093/eurjpc/zwaf376

Lina Lilja, Maria Bygdell, Jari Martikainen, Huiqi Li, Caroline Schmidt, Göran Bergström, Annika Rosengren, Claes Ohlsson, Jenny M Kindblom

{"title":"BMI during childhood and puberty - associations with blood pressure and hypertension.","authors":"Lina Lilja, Maria Bygdell, Jari Martikainen, Huiqi Li, Caroline Schmidt, Göran Bergström, Annika Rosengren, Claes Ohlsson, Jenny M Kindblom","doi":"10.1093/eurjpc/zwaf376","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf376","url":null,"abstract":"Aim: The present study aimed to evaluate the association between BMI during childhood and puberty and blood pressure and hypertension in midlife, and to explore midlife BMI as a potential mediator of these associations.Method: We linked the BMI Epidemiology Study Gothenburg (BEST) with developmental BMI, with the Swedish CArdioPulmonary bioImage Study (SCAPIS) with blood pressure and hypertension in midlife (n= 2394). The associations between childhood BMI (7-8 years) and pubertal BMI change (young adult BMI minus childhood BMI), and blood pressure and hypertension in midlife, were evaluated using linear or logistic regression models. Mediation analysis was conducted to evaluate the indirect effect, via midlife BMI, and the direct effect on blood pressure and hypertension. The analyses were adjusted for birth year and smoking.Results: The pubertal BMI change was positively associated with systolic and diastolic blood pressure and hypertension in midlife, independent of childhood BMI, in both men and women (p<0.01). For men but not for women, childhood BMI was positively associated with systolic and diastolic blood pressure in midlife, independent of the pubertal BMI change (p<0.01). No significant independent association was observed for childhood BMI with hypertension. Mediation analyses for the association between the pubertal BMI change and blood pressure and hypertension in midlife indicate that these associations were largely mediated by BMI in midlife.Conclusion: These findings indicate that high blood pressure may originate in early life. A life-course approach for targeted prevention, starting already during the developmental years, could reduce the risk of high blood pressure.","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Balancing Methodological Rigor and Clinical Relevance in Lipid Variability Research. 平衡方法的严谨性和临床相关性脂质变异性研究。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-06-25 DOI: 10.1093/eurjpc/zwaf372

Jeonggyu Kang, Byung Jin Kim

引用次数: 0

Exposure to ultra-processed food and risk of cardiovascular mortality: a prospective cohort study. 接触超加工食品与心血管死亡风险：一项前瞻性队列研究

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-06-25 DOI: 10.1093/eurjpc/zwaf378

Sarah Gauci, Mojtaba Lotfaliany, Priscila Machado, Allison Hodge, Elizabeth Gamage, Renata Bertazzi Levy, Maria Laura da Costa Louzada, Julie Redfern, Adrienne O'Neil, Wolfgang Marx, Melissa M Lane

{"title":"Exposure to ultra-processed food and risk of cardiovascular mortality: a prospective cohort study.","authors":"Sarah Gauci, Mojtaba Lotfaliany, Priscila Machado, Allison Hodge, Elizabeth Gamage, Renata Bertazzi Levy, Maria Laura da Costa Louzada, Julie Redfern, Adrienne O'Neil, Wolfgang Marx, Melissa M Lane","doi":"10.1093/eurjpc/zwaf378","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf378","url":null,"abstract":"Aims: There has been a global shift from nutrient-dense diets to an ultra-processed food pattern, which is linked to adverse health outcomes, including cardiovascular mortality. However, there is limited evidence in an Australian setting. Furthermore, many people in Australia have emigrated from countries with heart-healthy diets. This study explored the association between ultra-processed food exposure and cardiovascular mortality in an Australian cohort.Method and results: Data were derived from the Melbourne Collaborative Cohort Study. Food frequency questionnaire data collected at baseline were used to estimate ultra-processed food consumption according to the Nova classification system. Cardiovascular deaths were identified using data linkage between baseline (1990-94) and 31 March 2019. Fine and Gray competing risk models were fitted to assess the association between energy-adjusted ultra-processed food exposure and cardiovascular mortality, accounting for other types of mortality as competing risks. We included 39,544 participants (mean age 55.1 years at baseline, 60% female). During the follow-up period, which spanned 919,379 person-years and a median follow-up of 25.1 years, 4,229 cardiovascular deaths occurred. After adjusting for sociodemographic, lifestyle, and health-related factors, participants with the highest relative intake of ultra-processed food had 19% higher risk of cardiovascular mortality (Hazard Ratio high (quartile 4) vs. low (quartile 1) category = 1.19, 95% Confidence Intervals: 1.09 to 1.29, p-value for trend <0.001).Conclusions: Aligning with findings from the United States and Europe, higher exposure to the ultra-processed food pattern was prospectively associated with a higher risk of cardiovascular mortality.","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-Sensitivity C Reactive Protein Mediates Age-Related Vascular Dysfunction: The Rotterdam Study. 高敏C反应蛋白介导年龄相关血管功能障碍：鹿特丹研究

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-06-25 DOI: 10.1093/eurjpc/zwaf370

Soroush Mohammadi Jouabadi, Annique Claringbould, A H Jan Danser, Bruno H Stricker, Maryam Kavousi, Anton J M Roks, Fariba Ahmadizar

{"title":"High-Sensitivity C Reactive Protein Mediates Age-Related Vascular Dysfunction: The Rotterdam Study.","authors":"Soroush Mohammadi Jouabadi, Annique Claringbould, A H Jan Danser, Bruno H Stricker, Maryam Kavousi, Anton J M Roks, Fariba Ahmadizar","doi":"10.1093/eurjpc/zwaf370","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf370","url":null,"abstract":"Aim: To investigate the role of chronic low-grade systemic inflammation-specifically high-sensitivity C-reactive protein (hsCRP)-in mediating the relationship between aging and vascular dysfunction, and to assess its causal contribution relative to lipid metabolism. We also examined sex-specific mediation to evaluate differences in inflammatory pathways between men and women.Methods: We analyzed data from the Rotterdam Study, including 7,591 participants with longitudinal carotid intima-media thickness (cIMT) and 6,488 with cross-sectional pulse wave velocity (PWV) data. Mediation analysis assessed the roles of hsCRP, total cholesterol, and HDL in the age-vascular dysfunction association accompanied by sex-stratification. Two-sample Mendelian Randomization (MR) was conducted to explore the potential causal effects of hsCRP on vascular outcomes.Results: hsCRP significantly mediated the effect of age on cIMT (2.66%, p = 0.001) and PWV (2.56%, p = 4.95×10-9), with mediation magnitudes comparable to those of lipid markers and stronger in men compared to women. MR analyses provided genetic support for a potential causal relationship between hsCRP and PWV, but not cIMT.Conclusion: Systemic inflammation indexed by hsCRP appears to mediate and potentially contribute causally to age-related vascular stiffness particularly in men. These findings support the role of inflammation in functional vascular aging and suggest that anti-inflammatory strategies may complement lipid-lowering approaches in reducing cardiovascular risk.","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic Syndrome Adversely Impacts Mortality from Steatotic Liver disease. 代谢综合征对脂肪变性肝病死亡率有不利影响。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-06-25 DOI: 10.1093/eurjpc/zwaf364

Robert S Rosenson, Jeffrey I Mechanick

引用次数: 0

Beyond the mutation: unpacking cardiovascular risk in the familial hypercholesterolemia phenotype. 超越突变：揭示家族性高胆固醇血症表型的心血管风险。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-06-25 DOI: 10.1093/eurjpc/zwaf375

Stephanie Könemann, Kristin Lehnert, Martin Bahls

引用次数: 0

Colchicine in Atherosclerotic Cardiovascular Disease - Weighing up the evidence so far. 秋水仙碱在动脉粥样硬化性心血管疾病中的作用——权衡迄今为止的证据。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-06-25 DOI: 10.1093/eurjpc/zwaf380

Mau T Nguyen, Adam J Nelson, Peter J Psaltis

引用次数: 0

Vaccination in patients with heart failure in practice. 心力衰竭患者接种疫苗的实践。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-06-25 DOI: 10.1093/eurjpc/zwaf366

François Roubille, Nicolas Chapet, Camille Roubille, Marc Villacèque, Clément Delmas, Muriel Salvat, Frédéric Mouquet, Thibaud Damy, Jean-Michel Tartiere, Emmanuelle Berthelot, Peter Libby, Gianluigi Savarese, Paul Loubet, Nicolas Girerd

{"title":"Vaccination in patients with heart failure in practice.","authors":"François Roubille, Nicolas Chapet, Camille Roubille, Marc Villacèque, Clément Delmas, Muriel Salvat, Frédéric Mouquet, Thibaud Damy, Jean-Michel Tartiere, Emmanuelle Berthelot, Peter Libby, Gianluigi Savarese, Paul Loubet, Nicolas Girerd","doi":"10.1093/eurjpc/zwaf366","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf366","url":null,"abstract":"This narrative review underscores the pivotal role of vaccination in mitigating respiratory infections and associated acute decompensations in heart failure (HF) patients. It highlights the necessity for heightened awareness and proactive engagement among healthcare providers to bridge vaccination gaps and enhance preventive care for HF patients. Respiratory pathogens, such as influenza, pneumococcus, SARS-CoV2, and Herpes zoster virus (VZV), instigate systemic inflammation and increase cardiovascular events, markedly elevating the risk of HF and strokes, especially in individuals with preexisting conditions. Respiratory infections further amplify the risk of thrombotic events in HF patients through mechanisms involving a heightened procoagulant status due to inflammation. Systemic inflammation often accompanies HF, contributing to its progression, complications, and acute episodes, particularly during respiratory infections. While promising therapeutic approaches are under development, the review aims to provide a comprehensive overview of the pathophysiology linking inflammation, infection, and HF. The review then explores current clinical knowledge on the protective effects of vaccines against respiratory diseases (influenza, pneumococcal infection, SARS-CoV2, RSV, and emerging pathogens) in HF patients, along with the key applicable guidelines. It also offers strategies to enhance vaccination coverage in HF patients, highlighting practical issues pertinent to daily clinical practice.","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of excess mortality between atrial fibrillation, heart failure, myocardial infarction, and stroke: trends over 2000-2022. 心房颤动、心力衰竭、心肌梗死和中风之间超额死亡率的比较：2000-2022年的趋势。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-06-25 DOI: 10.1093/eurjpc/zwaf371

Nicklas Vinter, Søren Paaske Johnsen, Gregory Y H Lip, Emelia J Benjamin, Lars Frost, Ludovic Trinquart

{"title":"Comparison of excess mortality between atrial fibrillation, heart failure, myocardial infarction, and stroke: trends over 2000-2022.","authors":"Nicklas Vinter, Søren Paaske Johnsen, Gregory Y H Lip, Emelia J Benjamin, Lars Frost, Ludovic Trinquart","doi":"10.1093/eurjpc/zwaf371","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf371","url":null,"abstract":"Background and aims: Monitoring trends in mortality of atrial fibrillation (AF) in comparison with other major cardiovascular conditions indirectly gives insights into the relative progress in management. We examined trends in relative survival metrics of AF compared with heart failure (HF), myocardial infarction (MI), and stroke.Methods: This nationwide cohort study included all individuals newly diagnosed with AF, HF, MI, or stroke between 2000-2021. Relative survival and excess mortality rates were examined at 1, 5, and 10 years after diagnosis. The general Danish population served as the comparator, adjusted for age, sex, and calendar year.Results: The study included 364,199 patients with AF, 242,570 with HF, 172,552 with MI, and 281,407 with stroke. For relative survival, AF had the smallest average improvement over calendar years at 1 and 5 years after diagnosis (0.35% and 0.58% per year), while at 10 years, AF, MI, and stroke had the smallest average improvements (0.77%, 0.72%, and 0.80% per year). For excess mortality rate, AF and stroke had the smallest average improvements over calendar years at 1 year (-1.02 and -0.96 additional deaths per 1000 person-years per year) and MI at 5 years (-0.13 additional deaths per 1000 person-years per year). No average improvement was observed in the 10-year excess mortality rate for MI.Conclusions: AF was the condition or was among those with the smallest improvement in relative survival and AF and stroke showed the smallest improvement in 1-year excess mortality. The findings highlight the need for renewed efforts in prevention, early detection, and post-acute care for these conditions.","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0