European journal of preventive cardiology最新文献

{"title":"Chronotropic incompetency during stress echocardiography: a new paradigm for mortality and cardiac event prediction?","authors":"Attila Kardos, Casey Johnson, Paul Leeson","doi":"10.1093/eurjpc/zwaf550","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf550","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145250530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fueling Biomarker Discovery in Atrial Fibrillation: a case for Ketone Bodies?","authors":"Diego Penela, Giulio Falasconi, Eduard Guasch","doi":"10.1093/eurjpc/zwaf648","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf648","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-Specific Disparities in Lipid-Based Prediction of Major Cardiovascular Events.","authors":"L Schnetzer, A Muendlein, A Festa, C H Saely, H Drexel, A Leiherer","doi":"10.1093/eurjpc/zwaf646","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf646","url":null,"abstract":"<p><strong>Background: </strong>Lipid-based markers have a profound prognostic potential concerning cardiovascular diseases. However, differences in lipid levels between women and men are evident and it is unknown whether the differences also extend to the predictive power of the lipid markers. Therefore, this study aims to evaluate potential sex differences concerning the risk estimation of five topical lipid markers: low-density lipoprotein-cholesterol (LDL-C), remnant cholesterol, apolipoprotein A-1 (ApoA-1), the triglyceride/HDL-cholesterol (TG/HDL)-ratio, and ceramide scores (CERT1 and CERT2).</p><p><strong>Material and methods: </strong>In this prospective cohort study, the lipid markers were obtained for patients with high cardiovascular risk, who were followed for major cardiovascular events (MACE) for up to 14 years. The risk estimation was done for women (n=433) and age-matched men (n=433) separately using multiple performance and discrimination metrics.</p><p><strong>Results: </strong>Women showed higher LDL-C and ApoA-1 and lower remnant cholesterol and TG/HDL-ratio. Also, CERT1, but not CERT2, differed between the sexes, with women scoring slightly higher. During follow-up, MACE occurred in 25% of women and 37% of men. While an adjusted Cox regression demonstrated that remnant cholesterol significantly predicted MACE in both sexes, the ApoA-1 and TG/HDL-ratio was a predictor only in women, whereas ceramide-based scores predicted MACE solely in men. LDL-C showed no predictive potential in this high-risk cohort.</p><p><strong>Conclusion: </strong>To estimate cardiovascular risk, in several cases a sex-specific adaptation of lipid markers seems warranted.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of personalized step-count-based telerehabilitation during and after chemotherapy in breast cancer care.","authors":"Maarten Falter, Youri Bekhuis, Mauricio Milani, Sarah Coosemans, Marie Colson, Luka Herremans, Thibault Di Fiore, Ece Kizilkilic, Martijn Scherrenberg, Jeroen Mebis, Kristof Kempeneers, Ruta Jasaityte, Hanne Kindermans, Dominique Hansen, Guido Claessen, Paul Dendale, Jan Verwerft","doi":"10.1093/eurjpc/zwaf564","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf564","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145250500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerometer-Derived \"Weekend Warrior\" Physical Activity and Incident Cardiovascular Disease Among People with Diabetes.","authors":"Wenchang Yang, Puchen Zhou, Ruiqi Xia, Haiyang Dong, Xuan Wang, Hao Ma, Xiang Gao, Geng Zong","doi":"10.1093/eurjpc/zwaf632","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf632","url":null,"abstract":"<p><strong>Background: </strong>Current guidelines recommend ≥150 weekly minutes of moderate-to-vigorous physical activity (MVPA) for health, but how activity patterns affect outcomes is unclear. This study examined whether the \"weekend warrior\" (WW) pattern (i.e., most MVPA achieved over 1-2 days) was associated with a similar risk of incident cardiovascular disease (CVD) events as regular activity (RA) in adults with diabetes, using UK Biobank data.</p><p><strong>Methods: </strong>Physical activity was assessed via wrist-worn accelerometers and questionnaires. Participants were grouped by MVPA pattern and duration: WWs, RA, or inactive. Cox regression models estimated hazard ratios (HRs) and 95% CIs for associations between physical activity patterns and CVD incidence.</p><p><strong>Results: </strong>Among 3,061 participants with diabetes (mean [SD] age, 65.0 [7.1] years; 59.6% men), accelerometer-measured physical activity patterns were classified as WW (n=976), RA (n=503), and inactive (n=1,582). During a median follow-up of 6.6 years, a total of 254 (8.3%) incident CVD cases were identified. Compared with the inactive group, the multivariable-adjusted HRs for incident CVD in the RA and WW groups were 0.57 (95% CI: 0.38, 0.85) and 0.48 (95% CI: 0.34, 0.67), respectively. A comparison of WW versus RA for CVD risk showed no significant difference in the multivariable-adjusted HR of 0.85 (95% CI: 0.54, 1.34, p=0.50). Similar results were found in an additional analysis of 16,503 participants whose physical activity data were obtained via a questionnaire.</p><p><strong>Conclusion: </strong>This study shows that among participants with diabetes, WWs have a CVD risk similar to that of RA individuals, compared with inactive individuals.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145250579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontitis and Atrial Fibrillation.","authors":"Stanisław Surma, Gregory Y H Lip","doi":"10.1093/eurjpc/zwaf626","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf626","url":null,"abstract":"<p><p>Periodontitis is one of the most common inflammatory diseases worldwide, affecting over half of the population. It is a focus of chronic low-grade systemic inflammation, which is thought to contribute to the pathogenesis of cardiovascular diseases, including atrial fibrillation (AF), the most common supraventricular arrhythmia. A review of available epidemiological and pathophysiological studies, despite existing methodological limitations, indicates that individuals with moderate to severe periodontitis have a significantly higher risk of developing AF, and in patients already suffering from AF, the presence of periodontitis is associated with a poorer prognosis: a higher risk of recurrent arrhythmia, stroke, and cardiovascular events. Multiple mechanisms linking both diseases have been identified, including chronic immune activation, proinflammatory cytokines (CRP, IL-6, TNF-α), autoimmunity, atrial fibrosis, and the direct effects of oral pathogens (e.g., Porphyromonas gingivalis) on myocardial tissue. Furthermore, these diseases share many risk factors: obesity, diabetes, smoking, and low socioeconomic status. Scientific evidence indicates that periodontal treatment (scaling, periodontal therapy, improved oral hygiene) significantly reduces inflammatory markers and the risk of AF. The authors propose that oral health be considered as part of integrated care for patients with AF (ABC pathway). Despite the growing body of evidence, current cardiology guidelines do not address the role of periodontitis, indicating the need for updated standards of care. This narrative review summarizes the current knowledge regarding the relationship between periodontitis and AF.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145250550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How can we prevent the negative impact of adverse childhood and adolescent events on cardiovascular health?","authors":"Christian Albus","doi":"10.1093/eurjpc/zwaf640","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf640","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy in Women with Turner Syndrome: Balancing Reproductive Advances with Maternal Safety.","authors":"Andreina Carbone, Nupoor Narula, Eduardo Bossone","doi":"10.1093/eurjpc/zwaf642","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf642","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prognostic value of expiratory carbon monoxide level for outcome prediction after myocardial infarction.","authors":"Antoine Léquipar, Manveer Singh, Jean Guillaume Dillinger, Antonin Trimaille, Claire Bouleti, Clément Delmas, Guillaume Schurtz, Sonia Houssany-Pissot, Reza Rossanaly Vasram, Edouard Gerbaud, Damien Millischer, Amine El Ouahidi, Nabil Bouali, Emmanuel Gall, Christophe Thuaire, François Roubille, Nathalie Noirclerc, Stéphane Andrieu, Charles Fauvel, Alexandre Lafont, Sebastian Voicu, Nathan El Bèze, Charly Alizadeh, Paul Guiraud-Chaumeil, Jeremy Florence, Solenn Toupin, Victor Aboyans, Eric Vicaut, Théo Pezel, Patrick Henry","doi":"10.1093/eurjpc/zwaf559","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf559","url":null,"abstract":"<p><strong>Aims: </strong>To assess the prognostic value of expiratory carbon monoxide (CO) levels in patients admitted for myocardial infarction (MI).</p><p><strong>Methods and results: </strong>In this prospective study, expiratory CO levels were measured upon admission in consecutive patients hospitalized for MI across 39 centres. The primary outcome was 1-year all-cause death. Secondary outcomes included 1-year major adverse cardiac events (MACEs: cardiovascular death and recurrent MI) and in-hospital major adverse events (MAEs: death, severe ventricular arrhythmia, cardiogenic shock, and the need for mechanical ventilation). The prognostic value of expiratory CO levels was further evaluated using machine learning (ML) analysis. Among 717 patients (64 ± 13 years; 75% males; 33% active smokers; 43% ST-elevation MI), elevated expiratory CO levels (>11 ppm) were found in 79 patients (11%). Patients with elevated CO levels had a higher rate of 1-year all-cause mortality compared with those without (16.5% vs. 5.2%, P < 0.001). Elevated CO levels were independently associated with 1-year all-cause death across various adjustment models: comorbidities [odds ratio (95% confidence interval): 3.6 (1.7-7.5)], clinical parameters of in-hospital severity [4.5 (2.3-8.8)], and respiratory parameters [6.3 (3.1-12.8)]. Elevated CO levels were also independently associated with a significant increase in 1-year MACEs and in-hospital MAEs. Machine learning analysis identified CO level as one of the most important predictors of adverse events, compared with other known prognosticators.</p><p><strong>Conclusion: </strong>This is the first study to demonstrate that elevated expiratory CO levels upon admission are independently associated with an increased risk of 1-year all-cause mortality, 1-year MACEs, and in-hospital MAEs in patients hospitalized for MI.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opioids and Cardiovascular Health - The Past, Present and Future?","authors":"Ruairidh Duke, Rheure Alves-Lopes, Patrice Forget","doi":"10.1093/eurjpc/zwaf635","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf635","url":null,"abstract":"","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}