European journal of preventive cardiology最新文献_第4页

Sarcopenia : a new cardiovascular risk factor ? 肌肉减少症：一种新的心血管危险因素？

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-05-19 DOI: 10.1093/eurjpc/zwaf282

Olivier Hanon

引用次数: 0

Reply to "Oral Formulation and SGLT2i Interaction: Key Nuances in Semaglutide's Effect on Atrial Fibrillation". 回复“口服制剂和SGLT2i相互作用：西马鲁肽治疗心房颤动的关键细微差别”。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-05-19 DOI: 10.1093/eurjpc/zwaf298

Arturo Cesaro, Vincenzo Acerbo, Paolo Calabrò

引用次数: 0

The efficacy and safety of low dose colchicine in atherosclerotic cardiovascular disease - A systematic review and meta-analysis. 低剂量秋水仙碱治疗动脉粥样硬化性心血管疾病的疗效和安全性——一项系统综述和荟萃分析。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-05-16 DOI: 10.1093/eurjpc/zwaf302

Bradley Tucker, William J Tucker, Ji Soo Chung, Gemma A Figtree, Anthony Keech, Sanjay Patel

{"title":"The efficacy and safety of low dose colchicine in atherosclerotic cardiovascular disease - A systematic review and meta-analysis.","authors":"Bradley Tucker, William J Tucker, Ji Soo Chung, Gemma A Figtree, Anthony Keech, Sanjay Patel","doi":"10.1093/eurjpc/zwaf302","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf302","url":null,"abstract":"Aim: Colchicine has recently been approved for the treatment of atherosclerotic cardiovascular disease (ASCVD). Since then, three large trials of colchicine in ASCVD have failed to reach their primary endpoints.Method: A systematic search of PubMed, Embase and Cochrane Central Register of Controlled Trials was performed (PROSPERO registration: CRD42024616378). The primary endpoint of major adverse cardiovascular events (MACE) was defined as a composite of myocardial infarction, stroke and cardiovascular death. The key secondary endpoint of extended MACE (eMACE) was defined as MACE plus coronary revascularisation. Pooled estimates were calculated using a random-effects model and are presented as risk ratio (95% confidence interval).Results: 1624 articles were screened. 12 met inclusion criteria, yet one trial reported zero endpoint events in both arms. As such, 11 trials were included in the meta-analysis, with a total of 1983 primary endpoint events across 30,808 participants. Colchicine was associated with a 17% reduction in the incidence of MACE (0.83 [0.73, 0.95]; p=0.006) and 23% reduction in the incidence of eMACE (0.77 [0.63, 0.94]; p=0.01). This reduction was driven by a lower rate of myocardial infarction (0.78 [0.63, 0.95]; p=0.02) and coronary revascularisation (0.73 [0.55, 0.97]; p=0.03). There were also numerically fewer strokes in the colchicine treated population (0.81 [0.63, 1.04]; p=0.11). Colchicine had no effect on cardiovascular (0.96 [0.79, 1.15]; p=0.64) or non-cardiovascular mortality (1.04 [0.76, 1.41]; p=0.81).Conclusion: Colchicine reduces the risk of non-fatal ischaemic events in patients with ASCVD. Further studies are required to identify a population(s) who stands to benefit most from this promising therapy.","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Depression and Cardiovascular risk assessment: a multi-layered issue of equity and need? 抑郁症和心血管风险评估：一个多层次的公平和需求问题？

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-05-15 DOI: 10.1093/eurjpc/zwaf303

Caroline A Jackson

引用次数: 0

Cardiorespiratory fitness in adolescence and premature mortality: widespread bias identified using negative control outcomes and sibling comparisons. 青少年心肺健康与过早死亡：使用阴性对照结果和兄弟姐妹比较确定的广泛偏差。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-05-15 DOI: 10.1093/eurjpc/zwaf267

Marcel Ballin, Anna Nordström, Peter Nordström, Viktor Hugo Ahlqvist

引用次数: 0

Association between baseline adherence to a healthy lifestyle with ischemic and major cardiovascular events in patients with atrial fibrillation. 房颤患者基线坚持健康生活方式与缺血性和主要心血管事件的关系

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-05-14 DOI: 10.1093/eurjpc/zwaf287

Eva Soler-Espejo, María Pilar Ramos-Bratos, Eduardo González-Lozano, Gregory Y H Lip, Francisco Marín, José Miguel Rivera-Caravaca, Vanessa Roldán

{"title":"Association between baseline adherence to a healthy lifestyle with ischemic and major cardiovascular events in patients with atrial fibrillation.","authors":"Eva Soler-Espejo, María Pilar Ramos-Bratos, Eduardo González-Lozano, Gregory Y H Lip, Francisco Marín, José Miguel Rivera-Caravaca, Vanessa Roldán","doi":"10.1093/eurjpc/zwaf287","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf287","url":null,"abstract":"Aims: Managing modifiable risk factors and adherence to a healthy lifestyle are key in the holistic integrated care management of atrial fibrillation (AF). This study examines the relationship between a baseline healthy lifestyle and adverse clinical outcomes in AF patients.Methods: We included AF patients starting oral anticoagulation (OAC) between January 2016 and November 2021. Adherence to a healthy lifestyle was assessed at baseline using five modifiable lifestyle factors and patients were categorized into three groups based on points of adherence to modifiable factors: poor (0-8 points); moderate (9-12 points); high (13-17 points). The primary outcome was a composite of ischemic events, over a 2-years follow-up.Results: 3,266 AF patients were included (median age 77 [IQR 70-83] years), 52.8% female), and of these, 906 (27.7%) had high adherence. Incidence rate ratios were significantly lower in both the moderate adherence group (0.61; 95% CI 0.46-0.80) and the high adherence group (0.59; 95% CI 0.42-0.81) compared to the poor adherence group. Cox regression analyses adjusted for OAC type showed that high adherence to a healthy lifestyle significantly reduced the risk of composite ischemic events (aHR 0.58; 95% CI 0.42-0.79; p<0.001). After adjusting for additional risk factors, high adherence remained associated with lower risk of ischemic events (aHR 0.59; 95% CI 0.42-0.81; p=0.001). Similar results were observed for the secondary endpoints of MACE and ischemic stroke/TIA/systemic embolism; and in competing risk regression analyses.Conclusion: High baseline adherence to a healthy lifestyle reduced the risk of ischemic and major cardiovascular events in AF patients.","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A whisper from the endothelium: Can we hear it? 内皮细胞的低语：我们能听到吗？

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-05-14 DOI: 10.1093/eurjpc/zwaf299

Martin Bahls, Nicolle Kränkel

引用次数: 0

Comparison between the 6-minute walking test and gait speed during outpatient cardiac rehabilitation. 门诊心脏康复期间6分钟步行试验与步态速度的比较。

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-05-14 DOI: 10.1093/eurjpc/zwaf284

Duccio Rossini, Elio Venturini, Massimo Piepoli

引用次数: 0

Cardiovascular and Obstetric Safety of Pregnancy In Women With Premature Coronary Artery Disease. 早发冠心病妇女妊娠的心血管和产科安全

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-05-14 DOI: 10.1093/eurjpc/zwaf290

Meryem Mikou, Niki Procopi, Mathieu Kerneis, Johanne Silvain, Lise Legrand, Jacky Nizard, Gilles Montalescot, Michel Zeitouni

引用次数: 0

Burden and Long-term Impact of Pulmonary Embolism on Health-related Quality of Life: a Matched Cohort Study. 肺栓塞对健康相关生活质量的负担和长期影响：一项匹配队列研究

IF 8.4 2区医学

European journal of preventive cardiology Pub Date : 2025-05-14 DOI: 10.1093/eurjpc/zwaf307

Luca Valerio, Thomas Grochtdreis, Anna C Mavromanoli, Ioannis T Farmakis, Christina Abele, Thomas Neusius, Katharina Mohr, Konstantinos C Christodoulou, Lukas Hobohm, Karsten Keller, Alexander Konnopka, Stefano Barco, Stavros V Konstantinides

{"title":"Burden and Long-term Impact of Pulmonary Embolism on Health-related Quality of Life: a Matched Cohort Study.","authors":"Luca Valerio, Thomas Grochtdreis, Anna C Mavromanoli, Ioannis T Farmakis, Christina Abele, Thomas Neusius, Katharina Mohr, Konstantinos C Christodoulou, Lukas Hobohm, Karsten Keller, Alexander Konnopka, Stefano Barco, Stavros V Konstantinides","doi":"10.1093/eurjpc/zwaf307","DOIUrl":"https://doi.org/10.1093/eurjpc/zwaf307","url":null,"abstract":"Aims: It has not been conclusively established whether and to what extent pulmonary embolism (PE) affects health-related quality of life (HrQoL). We aimed to assess the long-term independent association of PE with HrQoL to provide reference values for interventional studies and support quantification of the burden of PE in terms of quality- or disability-adjusted life years (QALYs and DALYs).Methods: A total of 1005 patients from a prospective multicenter study, followed 3 and 12 months after PE, were successfully matched to 3058 individuals from the general population of the same country based on age, sex, and key comorbidities. Differences between acute PE survivors and matched controls in the ordinal EQ-5D-5L HrQoL dimensions were assessed using multivariable ordinal regression, in the HrQoL index (reflecting overall HrQoL) using multivariable-adjusted mixed linear regression. Both multiple imputation and complete case analysis were performed.Results: Compared with controls, patients reported worse HrQoL in the dimensions self-care, usual activities, and anxiety/depression, and worse HrQoL index at both 3 (adjusted difference -0.04 [95% CI: -0.06, -0.039] in a range from 0 to 1) and 12 months (-0.02 [95% CI: -0.04, -0.01]) in the imputation analysis. Complete case analysis showed similar results. The annual disability weight of PE for DALY calculation was conservatively estimated at 0.03 (95% CI: 0.02, 0.04).Conclusion: PE was independently associated with a moderate decrease in HrQoL, which persisted 12 months after the acute episode despite partial recovery over time. This degree of impairment is comparable to that imposed by several other cardiopulmonary diseases.","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0