European Journal of Psychiatry最新文献

{"title":"\"Fluctuations in mental health symptoms from recruitment to baseline: implications for eligibility in clinical trials\"","authors":"Juliane Piasssechi de Bernardin Gonçalves , Homero Vallada , Giancarlo Lucchetti","doi":"10.1016/j.ejpsy.2025.100306","DOIUrl":"10.1016/j.ejpsy.2025.100306","url":null,"abstract":"","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 2","pages":"Article 100306"},"PeriodicalIF":2.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143620541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 12-month follow-up study of self-harming behaviors in a sample of adolescents","authors":"Javier Vera-Martínez , Francisco Díaz-Atienza , Pablo González-Domenech , Luis Gutiérrez-Rojas , Sara Jiménez-Fernández","doi":"10.1016/j.ejpsy.2025.100301","DOIUrl":"10.1016/j.ejpsy.2025.100301","url":null,"abstract":"","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 2","pages":"Article 100301"},"PeriodicalIF":2.5,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143580061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating an intervention program to reduce suicidal behavior in adolescents with psychiatric disorders: A protocol design","authors":"Veronica Fernandez-Rodrigues ,&nbsp;Wala Ayad-Ahmed ,&nbsp;Paola Marin-Santos ,&nbsp;Jose Manuel Lopez-Villatoro ,&nbsp;Alejandro de la Torre-Luque ,&nbsp;Teresa Bobes-Bascaran ,&nbsp;Jose Luis Carrasco ,&nbsp;Luis Olivares ,&nbsp;Marina Diaz-Marsa","doi":"10.1016/j.ejpsy.2025.100298","DOIUrl":"10.1016/j.ejpsy.2025.100298","url":null,"abstract":"<div><h3>Introduction</h3><div>Suicide is the leading cause of unnatural death in adolescents. In addition, between 7 and 17% of adolescents may engage in at least one suicide attempt, with prevalence being dramatically higher in adolescents with psychiatric pathology. Death by suicide is usually preceded by several attempts to take one's own life. Among the risk factors most consistently associated with suicidal intent is suicidal ideation. This study aims to evaluate the efficacy of the Self-Awareness of Mental Health (SAM) program enriching standard care, for adolescents at high suicide risk (mental disorder and high suicidal ideation).</div></div><div><h3>Methodology</h3><div>A randomized single-blind controlled clinical trial will be conducted with a sample of 116 adolescents with suicidal ideation and/or suicide attempt, referred by their psychiatrists from the Hospital Clínico San Carlos (Madrid, Spain). The cohort will be divided into two groups (an intervention group, in which the SAM intervention will be administered as an adjuvant to standard treatment; and a treatment-as-usual group). An extensive clinical assessment on risk factors for suicidal behavior and psychiatric symptoms will be applied up to four times: baseline, post (5 weeks), 3 and 6 months.</div></div><div><h3>Results</h3><div>Data collection is ongoing. This study will provide data on the effectiveness of the SAM intervention in reducing ideation, preventing the occurrence of suicide attempts, and mitigating emotional symptomatology, such as for anxiety and depression.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 2","pages":"Article 100298"},"PeriodicalIF":2.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic evidence of increased schizophrenia risk due to antidepressant use in European and East Asian populations","authors":"Zhiqiang Du ,&nbsp;Xiangjun Zhou ,&nbsp;Qin Zhou,&nbsp;Rongrong Lu,&nbsp;Ying Jiang,&nbsp;Haohao Zhu","doi":"10.1016/j.ejpsy.2025.100302","DOIUrl":"10.1016/j.ejpsy.2025.100302","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Understanding the relationship between antipsychotic drugs (ATDs) use and schizophrenia (SCZ) is crucial. Thus, the objective is to explore the bidirectional causal relationship between ATDs use and SCZ via Two-Sample Mendelian Randomization (TSMR) analysis, aiming to offer new insights for the clinical treatment of SCZ.</div></div><div><h3>Methods</h3><div>We employed data from Genome-Wide Association Studies (GWAS) and conducted TSMR analysis using the Inverse Variance Weighted (IVW) method. The results were evaluated using P-values, OR values, and 95% Confidence Intervals (95% CI) to assess the bidirectional causal relationship.</div></div><div><h3>Results</h3><div>At the genetic level, we found a bidirectional positive correlation between European ATDs use and SCZ [OR: 1.283, 95% CI: 1.136–1.449; P = 5.73E-05] and [OR: 1.130, 95% CI: 1.082–1.180; P = 4.27E-08]. East Asian ATDs use and SCZ also showed a positive correlation [OR: 1.174, 95% CI: 1.038–1.328; P = 0.011], while no significant causal relationship was found between East Asian SCZ and ATDs use [OR: 1.004, 95% CI: 0.999–1.009; P = 0.161]. Sensitivity analysis further supported the robustness and reliability of these findings.</div></div><div><h3>Conclusion</h3><div>At the genetic level, we found that European and East Asian ATDs use may increase the risk of developing SCZ. This can help in formulating clinical medication strategies, where more caution may be needed in deciding whether to prescribe ATDs to SCZ patients. Additionally, we discovered that European SCZ might increase ATDs use, whereas no such risk was found in East Asians.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 2","pages":"Article 100302"},"PeriodicalIF":2.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between psychological pain and suicidal behaviour in a cohort of patients at high risk of suicide","authors":"Ana Pérez-Balaguer ,&nbsp;Inmaculada Peñuelas-Calvo ,&nbsp;Ana María de Granda-Beltrán ,&nbsp;Jimena María Merayo-Cano ,&nbsp;Berta Ezquerra ,&nbsp;Adrián Alacreu-Crespo ,&nbsp;Enrique Baca-García ,&nbsp;Alejandro Porras-Segovia","doi":"10.1016/j.ejpsy.2025.100299","DOIUrl":"10.1016/j.ejpsy.2025.100299","url":null,"abstract":"<div><h3>Background and Objectives</h3><div>Suicide is a major global public health issue. Pain, both psychological and physical, are potential risks factors for suicidal behaviour (SB). This study aims to explore the relationship between psychological and physical pain and SB in individuals at high risk of suicide.</div></div><div><h3>Methods</h3><div>This prospective cohort study included 322 participants recruited from emergency departments, psychiatric inpatient units, and outpatient mental health services in two hospitals in Madrid (Spain). Participants completed assessments at baseline and six months. Psychological and physical pain were measured using validated Visual Analog Scales (VAS). The primary outcome was the occurrence of suicidal events, documented through medical records and follow-up interviews. Kaplan-Meier survival analyses estimated the occurrence of suicidal events after 6 months of follow-up. Factors associated with suicidal events were analysed using univariate and multivariate Cox regression models to identify independent predictors of SB.</div></div><div><h3>Results</h3><div>Severe psychological pain in the previous 15 days was significantly associated with an increased risk of SB (<em>p</em> = 0.017), independently of depression severity. Younger age also emerged as a significant risk factor. No association was found between physical pain and SB.</div></div><div><h3>Conclusions</h3><div>Psychological pain is a key predictor of SB and should be a focus in suicide risk assessments. Further research is needed to improve measurement tools and develop targeted interventions in order to treat psychological pain effectively.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 3","pages":"Article 100299"},"PeriodicalIF":2.5,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143471241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in emergency health care due to suicidal behaviour in youth and adult populations","authors":"Sofía Abascal-Peiró ,&nbsp;Alejandro Porras-Segovia ,&nbsp;Blanca Margarit-Parrondo ,&nbsp;Enrique Baca-García","doi":"10.1016/j.ejpsy.2025.100296","DOIUrl":"10.1016/j.ejpsy.2025.100296","url":null,"abstract":"<div><h3>Background and Objectives</h3><div>Since the outbreak of the COVID-19 pandemic, there has been a significant increase in mental health-related ED visits, especially in child and adolescent population. This study aims to analyze trends in emergency care for mental health, including suicidal behaviour, in adolescents over seven years, and compare them with adults.</div></div><div><h3>Methods</h3><div>This observational and retrospective study included 33,376 visits, involving 12,159 individuals, to the ED for mental health issues between 2015 and 2021 from two hospitals in Madrid (Hospital Fundación Jiménez Díaz and Hospital Rey Juan Carlos). Sociodemographic and clinical data were collected from electronic health records. Logistic regression models were used to identify factors associated with presentations for suicidal behavior, with odds ratios (OR) and 95 % confidence intervals (95 %CI).</div></div><div><h3>Results</h3><div>In adults, presenting to the emergency department for suicidal behaviour was significantly associated with family history of suicide (OR=1.497, 95 %CI [1.250–1.794]), higher number of previous suicide attempts (OR=1.376, 95 %CI [1.331–1.422]), and substance intoxication (OR=1.317, 95 %CI [1.132–1.533. In children and adolescents, previous suicide attempts (OR=1.803, 95 %CI [1.485–2.189]), being female (OR=1.848, 95 %CI [1.281–2.666]) and older age (OR=1.113, 95 %CI [1.015–1.222]) were associated with higher odds of presenting for suicidal behaviour. Neurodevelopmental disorders were also significantly associated with increased odds of presenting for suicidal behaviour (OR=5.328, 95 %CI [2.353–12.063]), while psychotic disorders (OR=0.133, 95 %CI [0.032–0.548]) and anxiety disorders (OR=0.282, 95 %CI [0.128–0.622]) were linked to lower odds. In contrast to adults, the percentage of ED visits for suicidal behaviour in children and adolescents increased steadily over the study period, peaking at 30.3 % in 2020</div></div><div><h3>Conclusion</h3><div>These findings underscore the need for age- and gender-specific approaches in the management and prevention of suicidal crises in mental health emergency settings, with special attention to past suicidal behavior and family history as critical risk factors.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 3","pages":"Article 100296"},"PeriodicalIF":2.5,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143422027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Don't feel comfortable in your own skin? The relationship between body dissatisfaction and social media use – A meta-analytical approach","authors":"Thomas Vlasak ,&nbsp;Alfred Barth ,&nbsp;Christoph Augner","doi":"10.1016/j.ejpsy.2025.100297","DOIUrl":"10.1016/j.ejpsy.2025.100297","url":null,"abstract":"<div><h3>Objective</h3><div>This meta-analysis aims to clarify the relationship between body dissatisfaction (BD) and social media use.</div></div><div><h3>Methods</h3><div>We searched for relevant original studies via multiple data bases (i.e. Web of Science, Scopus, PubMed, etc.) until October 2023. Based on the included studies, we carried out a meta-analysis examining moderating effects and subgroup differences while testing the robustness of the relationship between BD and social media use against publication bias and influential cases.</div></div><div><h3>Results</h3><div>We included 18 studies with a total sample size of <em>n</em> = 24 384 participants with a mean age of 19.94 years (SD= 9.86) published from 2013 to 2022. Higher levels of social media use were significantly correlated with higher BD (<em>r</em> = 0.14 (95 % CI from 0.09 to 0.18, <em>p &lt;</em> .001). The positive association between social media use and BD is robust against outlier exclusion and considering heterogeneity (<em>r</em> = 0.13 (95 % prediction interval from 0.04 to 0.23, <em>p &lt;</em> .001).</div></div><div><h3>Conclusion</h3><div>Our results show that higher levels of social media use are significantly associated with higher BD. Key mechanisms behind the relationship are discussed.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 3","pages":"Article 100297"},"PeriodicalIF":2.5,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143403258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The growing phenomenon of sharenting and its implications for psychiatry","authors":"Luis M. Rojo-Bofill","doi":"10.1016/j.ejpsy.2025.100295","DOIUrl":"10.1016/j.ejpsy.2025.100295","url":null,"abstract":"","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 3","pages":"Article 100295"},"PeriodicalIF":2.5,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eating disorders and cardiovascular outcomes: A systematic review with meta-analysis","authors":"Cristiane Buzanello-Donin ,&nbsp;Monica Augusta Mombelli ,&nbsp;Márcia Rosângela Buzanello ,&nbsp;Clenise Maria Reis Capellani dos Santos ,&nbsp;Cassia Cristina Paes de Almeida ,&nbsp;Rogério da Luz ,&nbsp;Miguel Morita Fernandes da Silva","doi":"10.1016/j.ejpsy.2024.100274","DOIUrl":"10.1016/j.ejpsy.2024.100274","url":null,"abstract":"<div><h3>Background and objective</h3><div>To conduct a literature review to assess the association between eating disorders (ED), cardiovascular outcomes and all-cause mortality.</div></div><div><h3>Methods</h3><div>Observational studies that presented a measure of association between mortality (or cardiac outcomes) and EDs in adult or adolescent patients were included. The databases PubMed, Web of Science, EMBASE, Livivo, Scopus, PsycINFO and Lilacs were consulted. The random effect was adopted to group the findings of the primary studies in the meta-analysis using the Hazzard Ratio (HR) as a measure of association.</div></div><div><h3>Results</h3><div>The meta-analysis with 50,263 patients with ED showed a higher risk of mortality from all causes in patients compared to controls. The associated risk of death from all causes was higher with anorexia (AN) compared to other ED (AN: HR 5.38; 95 %CI 4.42 to 6.56; binge ED: HR 2.48; 95 %CI 1.13 to 5.46; bulimia: HR 2.21; 95 %CI 1.70 to 2.87). Additionally, one study demonstrated an association between bulimia and an increased risk of developing cardiovascular disease (HR 4.25; 95 %CI 2.98 to 6.07) and another study showed a higher risk of cardiovascular events in people with bulimia than in healthy controls (HR 1.4; 95 %CI 0.7 to 2.8). Finally, a higher risk of cardiovascular events in people with AN (HR 10.4; 95 %CI 2.6 to 41.6) was demonstrated in one study, when compared to healthy controls.</div></div><div><h3>Conclusions</h3><div>There is an association between EDs and all-cause mortality, with AN being associated with the highest risk, followed by binge ED and bulimia.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 2","pages":"Article 100274"},"PeriodicalIF":2.5,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143172281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of bright light therapy in patients suffering from unipolar or bipolar depression; A naturalistic study","authors":"M.A. Riedinger ,&nbsp;G.E. van Son ,&nbsp;N.J.A. van der Wee ,&nbsp;E.J. Giltay ,&nbsp;M. de Leeuw","doi":"10.1016/j.ejpsy.2025.100294","DOIUrl":"10.1016/j.ejpsy.2025.100294","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Depressive disorders, both unipolar (MDD) and bipolar (BD), impact patients and society greatly. In bipolar depression and seasonal affective disorder the episodic nature and periodicity relate to changes in circadian rhythms. Bright light therapy (BLT) is thought to ameliorate symptoms of depression through its influence on circadian rhythms. Effectiveness of BLT has not been thoroughly established in real-world clinical samples.</div></div><div><h3>Methods</h3><div>For seventy-four patients with depression Inventory of Depressive Symptoms – Self Rated (IDS-SR) scores were available through Routine Outcome Monitoring (ROM) used in BLT in the outpatient clinic for mood disorders. Patients received one or two weeks of add-on BLT as usual care. Patients suffering from MDD (<em>n</em> = 33, 60.6 % female, mean age 36.1 ± 11.5 years) were compared to patients suffering from BD (<em>n</em> = 41, 70.7 % female, mean age 45.0 ± 14.5 years) and changes in individual symptoms were analyzed for these two groups as well as the whole cohort.</div></div><div><h3>Results</h3><div>IDS-SR scores decreased significantly in both groups of patients and did not differ in effect size between the groups. Explorative analyses of the effects on individual items of the IDS-SR showed that items related to core symptoms of depression such a as mood, concentration and energy level showed the largest improvements.</div></div><div><h3>Conclusion</h3><div>Self-report depressive symptoms in patients suffering from either MDD or BD decreased in this naturalistic cohort after receiving BLT.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 3","pages":"Article 100294"},"PeriodicalIF":2.5,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143136440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}