Functional impairments in attention-deficit/hyperactivity disorder and emotional dysregulation subgroups: A latent profile analysis in a large cohort of 13,207 children and adolescents

IF 2.5 4区医学 Q2 PSYCHIATRY

European Journal of Psychiatry Pub Date : 2025-04-11 DOI:10.1016/j.ejpsy.2025.100310

Wenyan Zhang , Xiaohui Song , Xianbin Wang , Zhongliang Jiang , Xu Hong , Tianyuan Lei , Yonghua Cui

{"title":"Functional impairments in attention-deficit/hyperactivity disorder and emotional dysregulation subgroups: A latent profile analysis in a large cohort of 13,207 children and adolescents","authors":"Wenyan Zhang , Xiaohui Song , Xianbin Wang , Zhongliang Jiang , Xu Hong , Tianyuan Lei , Yonghua Cui","doi":"10.1016/j.ejpsy.2025.100310","DOIUrl":null,"url":null,"abstract":"<div><h3>Background and objectives</h3><div>The co-occurrence of attention-deficit/hyperactivity disorder (ADHD) symptoms and emotional dysregulation is highly prevalent. This study aims to explore potential subgroups within child and adolescent cohorts concerning ADHD symptoms and emotional dysregulation.</div></div><div><h3>Methods</h3><div>The sample comprised 13,207 children and adolescents aged 4–16 years diagnosed with ADHD recruited from outpatient services at the Beijing Children's Hospital. Latent profile analysis (LPA) was used to identify subgroups based on ADHD symptoms and emotional dysregulation across different age groups (children, 4–9 years, vs. adolescents, 10–16 years). Furthermore, analysis of covariance (ANCOVA) was employed to compare differences in behavioral problems, cognitive impairments, and social dysfunctions among these subgroups.</div></div><div><h3>Results</h3><div>We identified four distinct latent subgroups in children and three in adolescents. Significant differences in behavioral problems, cognitive impairments, and social dysfunctions were observed across these subgroups in both cohorts. Subgroups with high levels of ADHD symptoms and emotional dysregulation exhibited more severe functional impairments across both age groups.</div></div><div><h3>Conclusions</h3><div>This study highlights developmental variations in the relationship between ADHD symptoms and emotional dysregulation, underscoring the need for tailored interventions based on age-specific profiles.</div></div>","PeriodicalId":12045,"journal":{"name":"European Journal of Psychiatry","volume":"39 3","pages":"Article 100310"},"PeriodicalIF":2.5000,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Psychiatry","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0213616325000217","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

Abstract

Background and objectives

The co-occurrence of attention-deficit/hyperactivity disorder (ADHD) symptoms and emotional dysregulation is highly prevalent. This study aims to explore potential subgroups within child and adolescent cohorts concerning ADHD symptoms and emotional dysregulation.

Methods

The sample comprised 13,207 children and adolescents aged 4–16 years diagnosed with ADHD recruited from outpatient services at the Beijing Children's Hospital. Latent profile analysis (LPA) was used to identify subgroups based on ADHD symptoms and emotional dysregulation across different age groups (children, 4–9 years, vs. adolescents, 10–16 years). Furthermore, analysis of covariance (ANCOVA) was employed to compare differences in behavioral problems, cognitive impairments, and social dysfunctions among these subgroups.

Results

We identified four distinct latent subgroups in children and three in adolescents. Significant differences in behavioral problems, cognitive impairments, and social dysfunctions were observed across these subgroups in both cohorts. Subgroups with high levels of ADHD symptoms and emotional dysregulation exhibited more severe functional impairments across both age groups.

Conclusions

This study highlights developmental variations in the relationship between ADHD symptoms and emotional dysregulation, underscoring the need for tailored interventions based on age-specific profiles.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

European Journal of Psychiatry PSYCHIATRY-

CiteScore

2.90

自引率

0.00%

发文量

审稿时长

43 days

期刊介绍： The European journal of psychiatry is a quarterly publication founded in 1986 and directed by Professor Seva until his death in 2004. It was originally intended to report “the scientific activity of European psychiatrists” and “to bring about a greater degree of communication” among them. However, “since scientific knowledge has no geographical or cultural boundaries, is open to contributions from all over the world”. These principles are maintained in the new stage of the journal, now expanded with the help of an American editor.