European Journal of Dentistry最新文献

{"title":"Effects of Different Dentin Surface Cleaning Protocols on Bond Strength of Dual-Cure Resin Cement Following Temporary Cementation.","authors":"Vichakorn Vongtavatchai, Boondarick Niyatiwatchanchai, Murali Srinivasan, Thantrira Porntaveetus, Junji Tagami, Anucharte Srijunbarl, Kornwasa Siripamitdul, Dusit Nantanapiboon","doi":"10.1055/s-0044-1800824","DOIUrl":"10.1055/s-0044-1800824","url":null,"abstract":"<p><p>The aim of this study was to compare the effectiveness of various cleaning protocols on the bond strength of dual-cure resin cement following temporary cementation.Fifty-two human third molars were sectioned to expose superficial dentin and divided into four groups: (1) fresh, noncontaminated dentin (control); (2) pumice cleaning; (3) pumice + sodium bicarbonate air polishing; and (4) pumice + 10-methacryloyloxydecyl dihydrogen phosphate (MDP) based cleaner. Groups 2, 3, and 4 were treated with noneugenol zinc oxide temporary cement, followed by their respective cleaning protocols. After the teeth were cleaned, the restorative procedure was performed. All dentin surfaces were then bonded with a composite restoration using dual-cure resin cement. Shear bond strength was tested using a universal testing machine until failure. Surface morphology was assessed using a scanning electron microscope (SEM), and energy-dispersive X-ray spectroscopy (EDS) was used to analyze the residual elements on the dentin surface.Group differences were analyzed using one-way analysis of variance (ANOVA), followed by Tamhane's post hoc test. Chi-squared tests were used to assess the differences in failure mode proportions among groups. All statistical analyses were conducted at a significance level of <i>p</i> < 0.05.ANOVA revealed significant differences in bond strength among the groups (<i>p</i> < 0.001). Post hoc analysis showed no significant difference in bond strength between the control group and the sodium bicarbonate air polishing or MDP-based cleaner groups. However, the pumice polishing group exhibited a significantly lower bond strength compared to all other groups (<i>p</i> < 0.001). SEM-EDS analysis confirmed incomplete removal of temporary cement with pumice polishing, as evidenced by residual cement and elevated levels of zinc and oxygen ions.Pumice polishing alone was insufficient for removing temporary cement, resulting in reduced bond strength of the subsequently applied resin cement. This study demonstrated that combining pumice with sodium bicarbonate air polishing or MDP-based cleaner effectively removed cement and restored bond strength to levels comparable to fresh, noncontaminated dentin.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"1025-1034"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness of Conventional and Advanced Aligning Archwires: The Insights of Two Randomized Clinical Trials.","authors":"Reyam M Noori, Omar K Ahmed, Ammar S Kadhum, Yassir A Yassir, Marco Di Blasio, Diana Russo, Marco Cicciù, Giuseppe Minervini","doi":"10.1055/s-0044-1795080","DOIUrl":"10.1055/s-0044-1795080","url":null,"abstract":"<p><p>This study aimed to compare the clinical effectiveness of four aligning archwires: Superelastic Nickel-Titanium (Superelastic-NiTi), SmartArch, Copper-Nickel-Titanium (Cu-NiTi), and Speed Tubular coaxial-Nickel-Titanium (Tubular coaxial-NiTi), regarding the alignment efficiency, associated perception of pain, and possibility of inducing root resorption.This study includes two randomized clinical trials run in parallel. Patients with 5 to 9 mm of mandibular anterior teeth crowding according to Little's irregularity index (LII) who needed fixed orthodontic appliances without extraction were randomly assigned to four groups of aligning archwires (each trial with two groups): 0.014-inch, 0.018-inch Superelastic-NiTi; 0.016-inch SmartArch; 0.014-inch, 0.018-inch Cu-NiTi; and 0.016-inch, 0.018-inch Tubular coaxial-NiTi. LII was measured pretreatment and every 4 weeks for the next 16 weeks. Pain perception was assessed using a visual analogue scale in the first 7 days after the placement of each archwire. Periapical radiographs for mandibular central incisors were taken pretreatment and after 16 weeks to assess root resorption. The alignment efficiency was tested using a repeated measures analysis of variance test with mixed factorial design (between and within-subject effect), while pain perception and root resorption were tested using the Kruskal-Wallis test and Wilcoxon signed-rank test.A total of 73 patients were recruited from different centers. The analysis included 64 patients who completed the trials. Neither clinical nor statistical significance was found between the groups regarding the alignment. Similarly, there was no significant difference between the four groups regarding pain perception and root resorption. However, root resorption was slightly more in the Superelastic-NiTi group than in the other groups.The short time that root resorption was reported.The four types of archwires performed comparably regarding the alignment efficiency, associated perception of pain, and the possibility of inducing root resorption.The trials included in this study were registered with ClinicalTrials.gov on May 26, 2022 (Registration number: NCT05391542) and August 18, 2022 (Registration number: NCT05510206).</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"985-997"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Effects of Bead Formation on the Physicochemical and Biological Properties of Electrospun Poly(lactic-co-glycolic Acid) (PLGA) Membranes: A Comparative Analysis.","authors":"Saaid Al Shehadat, Aghila Rani, Ola Al Shehadat, Ensanya Ali Abou Neel, Sunaina Shetty Yadadi, Natheer Al-Rawi, Khalil Abdelrazik Khalil","doi":"10.1055/s-0045-1804885","DOIUrl":"10.1055/s-0045-1804885","url":null,"abstract":"<p><p>This study investigates the impact of bead formation on the properties of electrospun poly(lactic-co-glycolic acid) (PLGA) membranes, particularly mechanical strength, uniformity, and cell adhesion, challenging the conventional belief that bead-free membranes are superior.Three types of PLGA membranes were fabricated: beaded (B), fibrous (F), and a mixed (M) configuration of beads and fibers. Morphological, chemical, and surface characteristics were analyzed using scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), and water contact angle measurements. Human dental pulp stem cells (DPSCs) were used to assess <i>in vitro</i> cell adhesion, proliferation, and viability across the different membrane types.SEM imaging revealed distinct morphologies among the different membranes produced via electrospinning. FTIR analysis revealed no significant differences in the chemical composition of the membranes. Contact angle measurements indicated that membranes B and M became more hydrophilic over time, while membrane F remained relatively hydrophobic. All membranes supported DPSCs growth, with membrane M facilitating deeper cell infiltration into the scaffold, indicating enhanced cell integration. Viability assays revealed no significant differences in cell proliferation after 7 days, demonstrating that bead presence did not impair cell growth.These findings suggest that bead formation in PLGA membranes may offer advantages, such as improved hydrophilicity and enhanced cell infiltration, without compromising cell viability. This study challenges the notion that bead-free membranes are inherently superior and highlights the potential of bead morphology in optimizing electrospun PLGA scaffolds for biomedical applications.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"1193-1202"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Nurses in Enhancing Removable Dental Prostheses Hygiene.","authors":"Ahmad Al Jaghsi, Dinesh Rokaya","doi":"10.1055/s-0045-1802570","DOIUrl":"10.1055/s-0045-1802570","url":null,"abstract":"<p><p>Nurses contribute significantly to the management and prevention of oral diseases by educating patients on correct removable dental prostheses (RDP) cleaning techniques. This article aimed to present the role of nurses in enhancing RDP hygiene and provide a practical guide for nurses.A thorough literature search was done regarding the role of nurses in enhancing RDP hygiene and providing a practical guide for nurses in Google Scholar and PubMed from 1984 until 2024. All the English-language papers were included in this article. Publications included original research papers, review articles, and book chapters. The articles included were reviewed and added to this report.Good oral hygiene is crucial in preventing infections, enhancing patient comfort, and reducing health risks like pneumonia or gum disease that can result from inadequate RDP care. Hospitals and healthcare providers are encouraged to prioritize RDP care protocols, offering training and ensuring access to necessary cleaning supplies to support nurses in their care. Nurses have an important role in supporting proper care for patients using removable dentures.Through best practices in RDP cleaning, correct storage, educating patients on how to care for their RDP, proper documentation, and follow-up, nurses can make a significant improvement in patient health outcomes.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"1205-1214"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of Lip, Tongue, Masseter, and Temporalis Muscle Contractions with Electromyography Tools as an Early Diagnostic Medium for Dentoalveolar Malocclusion.","authors":"Harun Achmad, Intan Sari Areni, Sumintarti Sumintarti, Sri Ramadhany, Reza Ardiansya, Sarwo Edy, Wesley Kuandinata","doi":"10.1055/s-0044-1795124","DOIUrl":"10.1055/s-0044-1795124","url":null,"abstract":"<p><p>This study aims to detect early class I, II, and III malocclusions through the muscle strength of the lips, tongue, masseter, and temporalis.The study subjects were 30 pediatric patients with predetermined criteria. The subjects were divided into class I, II, and III malocclusions where each classification of malocclusion amounted to 10 people. Subjects were differentiated according to gender and age. Tongue pressure during swallowing was recorded by a palatal measurement sensor system. The strength of the activity was assessed when the lip muscles resisted as hard as possible the traction plate placed between the teeth and the lips, then the force was connected to an electromyograph (EMG) to be measured. Temporal and masseter muscle contractions were assessed when the muscles performed swallowing, chewing, mouth opening, resting, mouth closing, and biting movements.Data analysis using the SPSS application was performed with the ANOVA test if the data distribution was normal, and if the data distribution was not normal, then the Kruskal-Wallis test was used. Significant data were evaluated by post-hoc tests using least significant difference if the data distribution was normal or the Mann-Whitney test if the data distribution was not normal.It was found that there was a significant difference in the left masseter muscle and left temporalis muscle.EMG can be considered as a tool to detect class I, II, and III malocclusions through muscle contraction. Biting and chewing positions have satisfactory EMG examination results for malocclusion detection. Age and gender of the child may affect the results of EMG examination in certain conditions.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"998-1007"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histological Assessment of the Anti-Inflammatory Effectiveness of Peperomia pellucida Extract Administered to the Gingival Sulcus in Rats Induced with Periodontitis.","authors":"Dewi Lidya Ichwana Nasution, Sri Tjahajawati, Ratna Indriyanti, Amaliya Amaliya, Widya Irsyad, Indah Puti Sabirin","doi":"10.1055/s-0045-1802950","DOIUrl":"10.1055/s-0045-1802950","url":null,"abstract":"<p><p>This study aims to assess the impact of <i>Peperomia pellucida</i> extract on periodontitis in rats, using the Papillary Bleeding Index (PBI), gingival index (GI), and histological evaluation of key inflammatory cells such as osteoclasts, osteoblasts, polymorphonuclear neutrophils (PMNs), macrophages, and fibroblasts to explore its potential in reducing inflammation and preserving periodontal tissue.The extract was prepared using the reflux method with 96% ethanol as a solvent, followed by phytochemical screening and antibacterial testing via the disk diffusion method. This <i>in vivo</i> study utilized a posttest control group experiment with 24 Wistar rats, divided into four groups: nonperiodontitis, no-treatment, chlorhexidine-treated (CHX), and extract-treated groups, with the latter three groups induced with periodontitis. Induction was performed using a 0.3-mm ligature wire and plaque from periodontitis patients, along with nicotine administration (0.001 mg/L) for 7 days. The extract group received a topical application of 2.5 µL of <i>P. pellucida</i> leaf extract, while the CHX group was administered 0.05 mL of CHX daily for 1 week. Observations of GI and PBI were made on days 0, 3, 5, and 7. Histological changes were assessed on day 7 by evaluating the cell counts of osteoclasts, osteoblasts, fibroblasts, macrophages, and PMNs.Data were analyzed using one-way analysis of variance and Kruskal-Wallis with Mann-Whitney post hoc tests for pairwise comparisons.Phytochemical analysis confirmed the presence of alkaloids, polyphenols, tannins, flavonoids, quinones, monoterpenoids, and sesquiterpenoids in <i>P. pellucida</i> extract. The extract demonstrated antibacterial activity against <i>Porphyromonas gingivalis</i>, a key pathogen in periodontitis. Clinical and histological assessments showed significant improvements in the extract-treated group, with outcomes comparable to the CHX-treated group after 7 days.Based on these findings, <i>P. pellucida</i> (L.) Kunth extract contains phytochemicals and exhibits antibacterial and anti-inflammatory properties, as demonstrated by clinical and histological parameters in rats induced with periodontitis.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"1092-1105"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Internalization and Colocalization of a Polyclonal Antibody Against Porphyromonas gingivalis FimA type I in Infected Cells.","authors":"Napaporn Apiratmateekul, Kusuma Jamdee, Chantarapim Pinnork, Nawarat Khumyat, Niratcha Chaisomboon, Jantipa Jobsri","doi":"10.1055/s-0044-1801302","DOIUrl":"10.1055/s-0044-1801302","url":null,"abstract":"<p><p>The aim of this work was to investigate the effect of a rabbit polyclonal antibody specific to <i>Porphyromonas gingivalis</i> FimA type I (FimI) protein internalized into <i>P. gingivalis</i> infected cells.Rabbits were immunized with <i>P. gingivalis</i> FimI protein and the serum was collected for immunoglobulin (Ig) purification. For visualization of the antibody inside the cells, it was labeled with Cy3 dye. Live <i>P. gingivalis</i> was labeled with PKH67 dye. Rabbit anti-FimI Ig-Cy3 was internalized into H357 cells infected with <i>P. gingivalis</i>-PKH67 by electroporation or coincubation. Location of the Ig or <i>P. gingivalis</i> was observed under fluorescence microscope or confocal microscope. Percentage of <i>P. gingivalis</i>-PKH67 infected cells was analyzed by flow cytometry.Normality of data distribution was tested by Shapiro-Wilk test. The data failed normality test and were further analyzed by Kolmogorov-Smirnov test.Rabbit anti-<i>P. gingivalis</i> FimI Ig-Cy3 and <i>P. gingivalis</i>-PKH67 were both located next to the nucleus. The rabbit anti-FimI Ig-Cy3 was able to enter H357 cells after the cells were cultured in the medium containing the labeled Ig for 16 hours. The location of the Ig was near the nucleus as found in cells electroporated with the Ig-Cy3. The percentage of <i>P. gingivalis</i>-PKH67 infected cells seemed to be decreased after the infected cells internalized anti-FimI Ig by electroporation. However, it was not statistically significance.Rabbit anti-<i>P. gingivalis</i> FimI Ig and <i>P. gingivalis</i> was colocalized near the nucleus. And the rabbit anti-FimI Ig was able to enter H357 cells by coincubation method.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"1078-1083"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Conditions, Salivary pH, Flow Rate, Phosphate Level, and Phosphorus Intake of Pre- and Postmenopausal Women.","authors":"Sri Tjahajawati, Anggun Rafisa, Namira Vahra Khairunnisa Aldrin, Hening Tjaturina Pramesti","doi":"10.1055/s-0044-1795076","DOIUrl":"10.1055/s-0044-1795076","url":null,"abstract":"<p><p>This study aimed to investigate salivary parameters, including pH, flow rate, phosphate levels, and phosphorus intake, to explore potential variations between postmenopausal and premenopausal women.This study included 68 postmenopausal and 94 premenopausal women. Inclusion criteria comprised women aged 45 to 65 years with a minimum menopausal duration of 2 years and women aged 21 to 40 years for premenopausal participants. Exclusion criteria involved systemic diseases and any dental treatments received in the last 6 months. Direct observation facilitated the visual detection of intraoral inflammation, ulcers, plaque, calculus, dental mobility, and caries. A questionnaire covering demographic data, dental pain, xerostomia, burning sensation, ulcer etiology and duration, and gingival bleeding etiology was administered. Phosphorus intake was assessed using a semiquantitative food frequency questionnaire. Unstimulated whole saliva, collected by spitting, was analyzed for various salivary parameters, such as pH, flow rate, and phosphate level. The atomic absorption spectrophotometer was used to determine subjects' salivary phosphate level.The difference in intraoral conditions between groups was analyzed using the chi-square or Fisher's exact test. For the comparison of salivary parameters and phosphorus intake between study groups, the ANOVA: univariate general linear model was utilized. The correlation between salivary phosphate levels and age, body mass index (BMI), blood pressure, and phosphorus intake was examined using Spearman's rank correlation.The postmenopausal group demonstrated a significantly higher prevalence (<i>p</i> < 0.005) of gingival swelling, gingival discoloration, gingival recession, plaque, calculus, caries, tooth mobility, xerostomia, and burning sensation. Following adjustments for age, BMI, and blood pressure, a statistically significant difference in salivary flow rate between groups was observed (<i>p</i> = 0.008). No significant differences were found in salivary pH (<i>p</i> = 0.764), salivary phosphate level (<i>p</i> = 0.142), or phosphorus intake (<i>p</i> = 0.323) between the two groups. There was no significant correlation between salivary phosphate levels and age (<i>p</i> = 0.747), BMI (<i>p</i> = 0.308), systolic blood pressure (<i>p</i> = 0.747), diastolic blood pressure (<i>p</i> = 0.622), and phosphorus intake (0.829) in both groups.Postmenopausal women exhibited a lower salivary flow rate compared with premenopausal women. No differences or correlations were observed in salivary phosphate level and phosphorus intake between the two groups.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"979-984"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical Elements and Thickness of Candida albicans Biofilm Induced by Glucose, Lactose, Protein, and Iron.","authors":"Indah Listiana Kriswandini, Sidarningsih Sidarningsih, Prawati Nuraini, Nur Mega Dwi Y, Mohammed Ahmed Aljunaid, Oki Fadhila","doi":"10.1055/s-0045-1808261","DOIUrl":"10.1055/s-0045-1808261","url":null,"abstract":"<p><p>Health is the most important aspect that needs to be considered, and the oral cavity cannot be separated from other parts. <i>Candida albicans</i> is a normal flora in the oral cavity that is a major cause of oral candidiasis. Research on biofilms can help prevent oral candidiasis infection in the community. Biofilms are involved in the pathogenesis and could be examined using an electron and fluorescence microscope, which can analyze the whole biofilm in actual conditions. This study aims to determine the chemical elements and thickness of <i>Candida albicans</i> biofilms induced by glucose, lactose, soy protein, and iron.This analytic observational study was carried out by observing the chemical elements and thickness of the biofilm by scanning electron microscopy with energy dispersive X-ray (SEM-EDX) and confocal laser scanning microscopy (CLSM). SEM-EDX data analysis used the EDAX APEX software and CLSM used the Olympus FluoView ver 4.2.a.SEM-EDX examination showed the formation of <i>Candida albicans</i> biofilm induced by glucose, lactose, soy protein, and iron with similarity in the percentage of the most constituent chemical elements, namely, oxygen, carbon, nitrogen, and phosphorus, and the least were sulfur. The thickest biofilm was found in the induction of iron, glucose, and lactose, and the thinnest was soy protein.The chemical elements of <i>Candida albicans</i> biofilm induced by four different inducers has the same percentage of the composition of elements, namely, oxygen, carbon, nitrogen, and phosphorus, and the least were sulfur and the thickest biofilm was by the induction of iron, glucose, and lactose, and the thinnest was by soy protein.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"1120-1126"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnesium Infusion on Dental Implants and Its Impact on Osseointegration and Biofilm Development: A Review.","authors":"Dyah Anindya Widyasrini, Mutiara Annisa, Siti Sunarintyas, Lakshman Samaranayake, Widowati Siswomihardjo","doi":"10.1055/s-0045-1806958","DOIUrl":"10.1055/s-0045-1806958","url":null,"abstract":"<p><p>Dental implants have gained global popularity as a treatment option for tooth loss. The success of dental implants depends on their optimal integration into the tissues of the alveolar bone and the periodontium. However, several factors can hinder the proper osseointegration of implants, with the growth of biofilm on the implant surface and subsequent peri-implant infections being significant concerns. To overcome this challenge, researchers have explored the incorporation of antimicrobial agents onto metallic implant surfaces to mitigate biofilm growth. Ideally these agents should promote osteogenesis while exhibiting antibacterial effects. Magnesium (Mg) has emerged as a promising dual-function implant coating due to its osteogenic and antibacterial properties. Despite several studies, the precise mechanisms behind osteoinductive and antimicrobial effect of Mg is unclear, as yet. This review aims to collate and discuss the utility of Mg as a dental implant coating, its impact on the osteogenic process, potential in mitigating microbial growth, and prospects for the future. A comprehensive literature search was conducted across several databases and the findings reveal the promise of Mg as a dual-function dental implant coating material, both as a standalone agent and in combination with other materials. The antibacterial effect of Mg is likely to be due to its (1) toxicity particularly at high concentrations, (2) the production or reactive oxygen species, and (3) pH modulation, while the osteoinductive effect is due to a complex series of cellular and biochemical pathways. Despite its potential both as a standalone and composite coating, challenges such as degradation rate, leaching, and long-term stability must be addressed. Further research is needed to understand the utility of Mg as an implant coating material, particularly in relation to its antibacterial activity, osseointegration, and longevity in the oral milieu.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"869-881"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}