European Journal of Dentistry最新文献

{"title":"Histone H3K9 Methylation Is Differentially Modified in Odontogenic Cyst and Tumors.","authors":"Ekarat Phattarataratip, Aroonwan Lam-Ubol","doi":"10.1055/s-0044-1791681","DOIUrl":"https://doi.org/10.1055/s-0044-1791681","url":null,"abstract":"<p><strong>Objectives: </strong> Histone modification in odontogenic lesions is mostly unexplored. Trimethylation of histone H3 at lysine residue 9 (H3K9Me3) has been studied in various pathologic conditions and showed biological significance promising for future therapeutic application. This study aimed to investigate the level and clinical relevance of the H3K9Me3 histone modification in odontogenic cysts and tumors.</p><p><strong>Materials and methods: </strong> A total of 105 cases of odontogenic lesions, comprising 30 odontogenic keratocysts (OKCs), 30 adenomatoid odontogenic tumors (AOTs), 30 ameloblastomas, and 15 dental follicles, were included in the study. The paraffin-embedded tissues were immunohistochemically stained for H3K9Me3. Both the intensity and the distribution of staining were evaluated and calculated as H-score. The correlation between the H3K9Me3 expression and the clinical characteristics of each lesion was evaluated.</p><p><strong>Statistical analysis: </strong> The Kruskal-Wallis test followed by Bonferroni's correction was performed to assess the differences in H-score among groups. In addition, Pearson's chi-squared test or Mann-Whitney <i>U</i> test was used to analyze potential factors that could affect protein expression.</p><p><strong>Results: </strong> The reduced enamel epithelium of the dental follicle showed uniformly strong H3K9Me3 expression. All odontogenic cysts and tumors examined demonstrated a significantly reduced H3K9Me3 level compared with dental follicles. The AOT showed the lowest H3K9Me3 level, followed by OKC and ameloblastoma. Its immunoreactivity was mainly localized in the basal and parabasal cells of OKC and the whorled/duct-like structures of AOT. Ameloblastoma exhibited marked variation in the H3K9Me3 level among cases. Notably, the upregulated H3K9Me3 was related to multilocularity of OKC and ameloblastoma.</p><p><strong>Conclusions: </strong> Histone H3K9 methylation is differentially expressed in odontogenic cysts and tumors. This epigenetic modification may contribute to the pathogenesis and aggressive behavior of odontogenic lesions.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Cross-sectional Designs on Torsional Resistance of Endodontic Nickel-Titanium Files: A Finite Element Study.","authors":"Natchaphon Nanthaprathip, Sarita Morakul, Sirawut Hiran-Us, Pairod Singhatanadgid","doi":"10.1055/s-0044-1791785","DOIUrl":"https://doi.org/10.1055/s-0044-1791785","url":null,"abstract":"<p><strong>Objectives: </strong> This study aimed to assess the influence of two key design parameters on the torsional resistance of endodontic rotary files: the ratio of the equivalent radius (<i>re</i> ) to the polar moment of inertia (<i>J</i>), or <i>re</i> /<i>J</i> ratio, and the percentage of the inner core area. Understanding these factors can guide the development of files with improved performance during root canal procedures.</p><p><strong>Materials and methods: </strong> Finite element analysis was employed to simulate the behavior of rotary files under torsional loading conditions. This method allowed for the investigation of maximum shear stress across various cross-sections (D₄-D₁₆) of the files. The relationship between the <i>re</i> /<i>J</i> ratio and the maximum shear stress was also evaluated. To assess the impact of cross-sectional design modifications on stress distribution, the study analyzed files with progressively changing configurations.</p><p><strong>Results: </strong> Regions situated outside the inner core circle experienced lower shear stress compared with a circular shaft. Furthermore, a strong linear correlation was observed between the maximum shear stress experienced by the file, the applied torque during operation, and the <i>re</i> /<i>J</i> ratio. Significantly, the study established a connection between the percentage of the inner core area and the torsional resistance of the file. Files with a larger inner core area exhibited a lower coefficient (<i>C</i>) within a newly derived torsional formula. This lower <i>C</i> value directly translated to a reduction in the maximum shear stress experienced by the file. In essence, files with a higher percentage of inner core area demonstrated enhanced torsional resistance, allowing them to withstand higher torsional loads encountered during root canal procedures.</p><p><strong>Conclusion: </strong> This study identified the <i>re</i> /<i>J</i> ratio and the percentage of inner core area as the most critical design factors influencing the torsional resistance of rotary files. Files with a lower <i>re</i> /<i>J</i> ratio and a larger inner core area experienced lower shear stress, resulting in enhanced torsional resistance and potentially reducing the risk of torsional fracture during use. These findings offer valuable insights for both clinicians selecting rotary files and manufacturers designing future iterations, ultimately contributing to improved safety and efficacy during root canal treatments.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Two Mini-implant Lengths in the Infrazygomatic Crest Region: A Randomized Clinical Trial.","authors":"Abbas F Alsaeedi, Mehdi Abdul-Hadi Alrubayee, Gautham Sivamurthy","doi":"10.1055/s-0044-1789015","DOIUrl":"https://doi.org/10.1055/s-0044-1789015","url":null,"abstract":"<p><strong>Objective: </strong>  Temporary anchorage devices (TADs) have revolutionized fixed orthodontic appliance treatment through anchorage controlling in the clinic and play an essential role in resolving many complex cases. Due to the limited space, there is a risk of injury to the roots while using interradicular microimplants. Therefore, the infrazygomatic crest (IZC) area can be an alternative mini-implant insertion site in the maxillary arch. The aim of the study was to evaluate the primary stability, pain perception, sinus penetration, late stability, and failure rate with two mini-implant lengths in the IZC area.</p><p><strong>Materials and methods: </strong> Forty-eight mini-implants (Tusk Dental Co., Ltd., Canada) with two different lengths (length/diameter: 12/2 and 14/2 mm) were grouped by length (24 per group) and inserted bilaterally into the IZC area of 24 patients. The data were statistically analyzed, considering a significance level of <i>p</i> < 0.05.</p><p><strong>Results: </strong> Sinus penetration prevalence did not differ significantly between 12-mm (54.2%) and 14-mm (62.5%) mini-implants (<i>p</i> > 0.05). Primary stability was significantly higher with the 14-mm mini-implants (<i>p</i> < 0.05). The failure rate did not differ significantly between the 12-mm (20.8%) and 14-mm (16.7%) mini-implants (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong> While the failure rate was similar between 12- and 14-mm mini-implants, the 14-mm mini-implants were more likely to damage adjacent structures. Therefore, shorter mini-implants should be preferred over longer mini-implants for most cases requiring IZC TADs.</p><p><strong>Trial registration id: </strong> ClinicalTrials.gov identifier: NCT06293872.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypoxia-Preconditioned Human Umbilical Cord Mesenchymal Stem Cells Transplantation Ameliorates Inflammation and Bone Regeneration in Peri-Implantitis Rat Model.","authors":"Mefina Kuntjoro, Nike Hendrijantini, Eric Priyo Prasetyo, Bambang Agustono, Guang Hong","doi":"10.1055/s-0044-1791530","DOIUrl":"https://doi.org/10.1055/s-0044-1791530","url":null,"abstract":"<p><strong>Objective: </strong> The failure of dental implant treatments is predominantly attributed to peri-implantitis, which entails chronic inflammation within the peri-implant tissue, ultimately leading to tissue degradation. Addressing this condition, human umbilical cord mesenchymal stem cell (hUCMSC) transplantation serves as a regenerative therapy; however, concerns regarding the viability and efficacy of transplanted cells in inflamed regions persist. Hypoxic preconditioning of hUCMSCs has emerged as a potential strategy for augmenting their regenerative and immunomodulatory capacities. This study aimed to evaluate the expression of inflammatory (tumor necrosis factor [TNF]-α) and bone regenerative biomarkers (nuclear factor of activated T-cell [NFATc1], osteocalcin, collagen type I alpha 1 [COL1α1]) within peri-implantitis models subsequent to the transplantation of hypoxia-preconditioned hUCMSCs.</p><p><strong>Materials and methods: </strong> Peri-implantitis models were established through the insertion of implants into the femur bone of 42 Wistar strain Rattus norvegicus, followed by intrasocket injection of lipopolysaccharide. The experimental animals were categorized into three groups (control, normoxia, and hypoxia) and underwent observation on days 14 and 28. The expression levels of TNF-α, NFATc1, COL1α1, and osteocalcin were evaluated using immunohistochemical staining, and the resulting data were subjected to one-way analysis of variance analysis (<i>p</i> < 0.05).</p><p><strong>Results: </strong> Transplantation of hypoxia-preconditioned hUCMSCs significantly ameliorated inflammation and osteoclastogenesis, as evidenced by significant reductions in TNF-α and NFATc1 expression compared with the control group. Furthermore, hypoxic preconditioning of hUCMSCs demonstrated a significant elevation in the expression of osteocalcin and COL1α1 relative to the control group.</p><p><strong>Conclusion: </strong> The transplantation of hypoxia-preconditioned hUCMSCs exhibited a capacity to ameliorate inflammation and enhance bone regenerative processes in peri-implantitis rat models.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Postorthodontic Occlusal Force Distributions between Nonextraction and Extraction Treatment Approaches of Premolars for Orthodontic Treatment by Using T-Scan III System.","authors":"Ratchawan Tansalarak, Nattapat Khamnuengsitthi, Mayurach Pipatphatsakorn","doi":"10.1055/s-0044-1789002","DOIUrl":"https://doi.org/10.1055/s-0044-1789002","url":null,"abstract":"<p><strong>Objective: </strong> To compare bite force distributions in corresponding mouth regions between postorthodontic patients who underwent nonextraction and extraction approaches using the T-Scan III system (Tekscan, Inc, Massachusetts, United States).</p><p><strong>Materials and methods: </strong> Thirty-six postorthodontic patients were divided into two groups: (1) 18 subjects with the nonextraction treatment and (2) 18 subjects with the extraction of four first-premolar treatments. The measurements were performed using the T-Scan to collect the occlusal bite force at the maximal intercuspal position to generate the bite force in the anterior region (incisors and canines) and posterior region (premolars and molars), the bite force in individual teeth, and the anteroposterior bite force ratio (A-P ratio).</p><p><strong>Statistical analysis: </strong> The mean bite force in each region, individual teeth, and the A-P ratio were compared between the two groups by the Mann-Whitney's <i>U</i>-tests. Within-group comparisons of the mean bite force in each region were performed using Wilcoxon's signed rank tests.</p><p><strong>Results: </strong> The bite force in anterior and posterior regions, and the A-P ratio of the nonextraction group show no significant difference compared with the extraction group (<i>p</i> > 0.05). For individual teeth (central incisors, lateral incisors, canines, second premolars, first molars, and second molars), each tooth exhibited nonsignificantly different bite forces (<i>p</i> > 0.05) except for the second molars. The second molars in the nonextraction group had significantly less bite force than in the extraction group (<i>p</i> = 0.001). The comparison of occlusal bite force between the right and left sides showed that in the nonextraction group, the right side had significantly greater force (<i>p</i> < 0.05). In the extraction group, there was no significant difference between the sides (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong> Both nonextraction and extraction orthodontic treated patients exhibited the similar bite force distribution patterns in regions and individual teeth except for the higher occlusal force on the second molars in the extractions compared with the nonextractions.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Cryotherapy and Occlusal Reduction on Postoperative Endodontic Pain in Mandibular First Molars with Symptomatic Apical Periodontitis: A Prospective, Parallel, Double-Blinded Randomized Controlled Trial.","authors":"Lana Almasoud, Tarek Elsewify, Ranya Elemam, Bassem Eid","doi":"10.1055/s-0044-1791219","DOIUrl":"https://doi.org/10.1055/s-0044-1791219","url":null,"abstract":"<p><strong>Objectives: </strong> This study aimed to compare the intensity of postoperative pain following the final rinse using cold saline compared with room temperature saline and occlusal reduction.</p><p><strong>Materials and methods: </strong> A prospective, parallel, double-blinded randomized controlled trial was conducted on 69 first mandibular molars diagnosed with symptomatic irreversible pulpitis and symptomatic apical periodontitis. Single-visit root canal treatment was performed; access cavity preparations and chemomechanical preparations were carried out using the ProTaper Gold rotary system under copious irrigation using 3% sodium hypochlorite and 17% EDTA. The patients were divided into three groups (<i>n</i> = 23): control group: room temperature saline (25°C) final rinse without occlusal reduction; cryotherapy group: cold saline (2.5-4°C) final rinse without occlusal reduction; and occlusal reduction group: room temperature saline with occlusal reduction. Pain scores were recorded using the visual analog scale preoperatively and postoperatively via telephone at 6, 24, 48, 72 hours, and 7 days intervals. Age data were analyzed using one-way analysis of variance followed by Tukey's post hoc test. Pain score data were analyzed using Kruskal-Wallis' test followed by Dunn's post hoc test for intergroup comparisons and Friedman's test followed by Nemenyi's post hoc test for intragroup comparisons. Correlations were analyzed using Spearman's rank-order correlation coefficient. The significance level was set at <i>p</i> < 0.05 within all tests.</p><p><strong>Results: </strong> Cryotherapy reduced postoperative pain compared with the control group with a statistically significant difference at 24 hours only (<i>p</i> = 0.016). At other intervals, no statistically significant difference in pain score was measured between all three groups (<i>p</i> > 0.05). After 7 days, all patients recorded a zero pain score.</p><p><strong>Conclusion: </strong> Cryotherapy was as effective as the occlusal reduction in reducing postoperative pain in cases of symptomatic irreversible pulpitis with symptomatic apical periodontitis, significantly more than the control group.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Regenerative Endodontic Therapy of a Dens Evaginatus Mandibular Second Premolar with an Acute Apical Abscess and Extensive Periapical Bone Loss: A Case Report.","authors":"Francesco J DeMayo, Jackson T Seagroves, Takashi Komabayashi","doi":"10.1055/s-0044-1791218","DOIUrl":"https://doi.org/10.1055/s-0044-1791218","url":null,"abstract":"<p><p>Regenerative endodontics is a rapidly growing field within dentistry that aims to replace damaged tooth structures and cells of the pulp-dentin complex. This case report presents the successful management of an immature permanent second mandibular premolar with an acute apical abscess and extensive apical bone loss caused by a dens evaginatus. This tooth was unexpectedly treated with long-term calcium hydroxide (Ca(OH)₂) that was replenished several times over 6 months. During the treatment process, this tooth became reinflamed developing a chronic apical abscess after resolution of the initial acute apical abscess, which resulted in the replacement and prolonged use of Ca(OH)₂. The final regenerative procedures were completed using a bioceramic fast set putty placed directly over the blood clot and an occlusal composite restoration. At the 6-month follow-up, the patient was asymptomatic with a fully healed radiographic lesion, new periodontal ligament, and the apex closed with thickening of the mesial and distal aspects of the root. At the 15-month follow-up, the patient remained asymptomatic with continued evidence of radiographic development of the apical aspect of this tooth, displaying root end closure and thickening. This is a unique case report of the management of a complex infection process in an immature tooth with regenerative techniques with repeated and long-term use of Ca(OH)₂. This novel report provides dental practitioners with a new potential protocol for the management of these immature cases with advanced periapical infections that require extensive disinfection to have successful outcomes.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142406271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-Etching Ceramic Primer Affects Surface Topography and Roughness of Two Zirconia-Reinforced Lithium Silicate Ceramics.","authors":"Feras Alhalabi","doi":"10.1055/s-0044-1787283","DOIUrl":"https://doi.org/10.1055/s-0044-1787283","url":null,"abstract":"<p><strong>Objective: </strong> This article evaluates the etching efficacy of a self-etching ceramic primer (SECP) on zirconia-reinforced lithium silicate (ZLS) ceramics.</p><p><strong>Materials and methods: </strong> Celtra Duo (DeguDent GmbH, Hanau-Wolfgang, Germany) and Vita Suprinity (Vita Zahnfabrik, Bad Säckingen, Germany) were used in this study. A total of 36 ceramic slices were prepared from each ceramic material and randomly distributed into three groups according to the surface treatment applied (<i>n</i> = 12 per group). Group 1 (polished) was polished with silicon carbide paper discs and did not undergo any surface treatment; group 2 (SECP) was surface treated with SECP (Monobond Etch and Prime, Ivoclar Vivadent, Schaan, Liechtenstein); group 3 (hydrofluoric acid [HF]) was surface treated with 4.7% HF etching. Half of the specimens (<i>n</i> = 6) from each group were gold-sputtered, and the surface topographic alterations were evaluated by scanning electron microscopy at magnifications of 5,000× and 10,000 × . The surface roughness of the other half (<i>n</i> = 6) from each group was tested using a three-dimensional optical profiler. Data were statistically analyzed using two-way analysis of variance and Tukey's multiple comparisons test.</p><p><strong>Results: </strong> Both SECP and HF etching surface treatments resulted in a statistically significant increase (<i>p</i> < 0.05) in the surface roughness of both ceramic materials, compared to that of their respective control group specimens (polished). HF etching resulted in a significant dissolution of the glassy phase of each ceramic.</p><p><strong>Conclusion: </strong> SECP can effectively etch ZLS ceramics. The etching patterns created after the application of SECP were mild compared to those produced by HF etching. The topographic surface features of ceramics are affected by both, surface treatment and material composition.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142406270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Two Different Intraoral Polishing Systems on Surface Roughness, Color Stability, and Bacterial Accumulation of Zirconia-Reinforced Lithium Silicate Ceramic.","authors":"Fatma Makkeyah, Dina Mohamed Moustafa, Mahmoud M Bakr, Mahmoud Al Ankily","doi":"10.1055/s-0044-1779423","DOIUrl":"10.1055/s-0044-1779423","url":null,"abstract":"<p><strong>Objective: </strong> The aim of this study was to investigate the effects of two intraoral polishing methods on zirconia-reinforced lithium silicate ceramic after ultrasonic scaling.</p><p><strong>Materials and methods: </strong> Thirty disc-shaped samples of zirconia-reinforced lithium silicate were constructed. Freshly extracted bovine teeth were collected and cleaned then the discs were cemented into a cavity prepared onto their labial surface. The samples were divided into three groups (10 samples per group); S: Scaling only, SE: Scaling followed by polishing using Eve Diapro lithium disilicate polishers, SD: Scaling followed by polishing using Diatech ShapeGuard ceramic polishing plus kit. The surface roughness was evaluated after scaling and polishing the samples. For color stability, the samples were stored for 12 days at 37°C in an incubator to simulate 1-year consumption of coffee. L*a*b* color parameters were assessed using VITA Easyshade Advance 4.0 before and after the staining procedure and the color difference was measured. Finally, bacterial accumulation was evaluated by incubating the samples with a suspension of <i>Streptococcus mutans</i> ( <i>S. mutans</i>), after that the <i>S. mutans</i> colonies were counted to obtain the values of colony-forming units (CFU). The final overall roughness, change in color and bacterial count were compared between all groups using one-way ANOVA and Tukey's post-hoc analysis. The Pearson correlation coefficient was used to determine the correlation between continuous variables. The cutoff for significance was chosen at <i>p</i> ≤ 0.05.</p><p><strong>Results: </strong> Scaling induced surface roughness of the zirconia-reinforced lithium silicate ceramic was significantly decreased after using both intraoral polishing systems and this was accompanied by a significant decrease in color change and bacterial count.</p><p><strong>Conclusion: </strong> Intraoral polishing techniques can reduce the roughness of the surface of zirconia reinforced lithium silicate restorations induced due to scaling and subsequently reduce the stainability and bacterial accumulation.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"1069-1075"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11479737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140331666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Genetics and Gene Polymorphism on Biological Complications for Dental Implant Survival: A Review.","authors":"Marcella Santos Januzzi, Daniela Micheline Dos Santos, Cleber Davi Del Rei Daltro Rosa, Karina Helga Leal Turcio, Clóvis Lamartine de Moraes Melo Neto, Maria Eduarda da Silva Fernandes, André Pinheiro de Magalhães Bertoz, Manuel Martin Adriazola Ique, Marcelo Coelho Goiato","doi":"10.1055/s-0044-1787820","DOIUrl":"10.1055/s-0044-1787820","url":null,"abstract":"<p><p>The objective of this review is to expose the main genetic changes and genetic polymorphisms that may or may not be associated with greater susceptibility to reduced survival of dental implants and, consequently, to their loss. Case-control studies that fully portrayed the specific types of genetic polymorphisms that may be associated with dental implant failure were included by searching in the PubMed, Scopus, and Web of Science databases from 2010 to 2023. The following descriptors and their combinations in English were used to search for articles: \"dental implants,\" \"bone genes,\" \"genetics,\" \"polymorphism genetics,\" \"genetic risk factor,\" and \"interleukin.\" The initial search resulted in 107 results (PubMed <i>n</i> = 47, Scopus <i>n</i> = 14, and Web of Science <i>n</i> = 46). After a manual search, reviewing each article's title and abstract, and excluding duplicates, systematic reviews, and literature reviews, 30 articles were selected. After reading these 30 articles in full, 18 studies that did not describe the specific genetic polymorphism in relation to dental implant survival were excluded. Therefore, 12 articles were included in this review. The genetic polymorphisms of interleukin (IL)-1A, IL-1B, IL-4, IL-6, IL-10, IL-1 receptor antagonist, tumor necrosis factor-α, receptor activator of nuclear factor kappa B legend, and cluster of differentiation 14 were analyzed in the included studies. In seven of the studies, a statistically significant correlation between genetic polymorphisms and dental implant failure was observed. Of the polymorphisms studied, IL-1A (-899), IL-1B (+3954), and IL-4 (+33) showed a greater association with dental implant loss.</p>","PeriodicalId":12028,"journal":{"name":"European Journal of Dentistry","volume":" ","pages":"971-975"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11479735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}