European Journal of Applied Physiology最新文献

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Physiological and perceptual response to critical power anchored HIIT: a sex comparison study. 临界功率锚定 HIIT 的生理和知觉反应:性别比较研究。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2024-09-05 DOI: 10.1007/s00421-024-05600-5
Lauren J Pacitti, Joshua Laberge, Kaitlyn E Shikaze, Patrick J Drouin, Michael E Tschakovsky, Chris McGlory, Brendon J Gurd
{"title":"Physiological and perceptual response to critical power anchored HIIT: a sex comparison study.","authors":"Lauren J Pacitti, Joshua Laberge, Kaitlyn E Shikaze, Patrick J Drouin, Michael E Tschakovsky, Chris McGlory, Brendon J Gurd","doi":"10.1007/s00421-024-05600-5","DOIUrl":"https://doi.org/10.1007/s00421-024-05600-5","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to test the hypothesis that using threshold-based high intensity interval training (HIIT<sub>THR</sub>) prescribed at an intensity above critical power (CP) in males and females matched for maximal oxygen uptake ( <math><mover><mtext>V</mtext> <mo>˙</mo></mover> </math> O<sub>2</sub>max) (mL/kg lean mass/min) will yield no sex differences in time to fatigue.</p><p><strong>Methods: </strong>Thirteen males (mean ± SD: 22.0 ± 2.48 years, 181 ± 8.36 cm, 78.8 ± 11.4 kg) and eleven females (mean ± SD: 22.4 ± 2.69 years, 170 ± 5.73 cm, 65.2 ± 7.66 kg) initially undertook an incremental test to exhaustion to determine <math><mover><mtext>V</mtext> <mo>˙</mo></mover> </math> O<sub>2</sub>max, and a CP test. Then, one HIIT session (4 min on, 2 min off) was performed to exhaustion at the work rate associated with 105%CP. Acute physiological and cardiovascular responses were recorded.</p><p><strong>Results: </strong>No sex differences were recorded in time to fatigue [Female vs. Male (min): 36.0 ± 18.5 vs. 39.3 ± 16.3], heart rate, rate of perceived exertion, or %oxygenated [haem]. Females displayed lower %deoxygenated [haem] at the end of interval 1, 2, 3, and 4 [Female vs. Male (%): 89.4 ± 21.2 vs. 110 ± 27.3, 92.0 ± 21.5 vs. 115 ± 27.6, 87.1 ± 23.7 vs. 112 ± 22.8, 88.9 ± 26.3 vs. 113 ± 23.5]. Large interindividual variability in performance, and physiological and perceptual response were present despite the use of threshold-based prescription.</p><p><strong>Conclusion: </strong>The present study suggests that threshold-based prescription may help standardize the mean response exercise across sexes but does not eliminate physiological or perceptual variability. Furthermore, the lack of sex differences in TTF was accompanied by greater %deoxy[haem] in males, indicating tissue oxygenation is an unlikely determinant of HIIT performance. This study has been retrospectively registered at Trial Registration https://doi.org/10.17605/OSF.IO/KZVGC January 17th, 2023, following data collection but prior to data analyses.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantifying exercise intensity with fractal correlation properties of heart rate variability: a study on incremental and constant-speed running. 利用心率变异性的分形相关特性量化运动强度:对增量跑和匀速跑的研究。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2024-09-05 DOI: 10.1007/s00421-024-05592-2
C R van Rassel, O O Ajayi, K M Sales, C A Clermont, M Rummel, M J MacInnis
{"title":"Quantifying exercise intensity with fractal correlation properties of heart rate variability: a study on incremental and constant-speed running.","authors":"C R van Rassel, O O Ajayi, K M Sales, C A Clermont, M Rummel, M J MacInnis","doi":"10.1007/s00421-024-05592-2","DOIUrl":"https://doi.org/10.1007/s00421-024-05592-2","url":null,"abstract":"<p><p>The short-term scaling exponent of detrended fluctuation analysis (DFAα1) applied to interbeat intervals may provide a method to identify ventilatory thresholds and indicate systemic perturbation during prolonged exercise. The purposes of this study were to (i) identify the gas exchange threshold (GET) and respiratory compensation point (RCP) using DFAα1 values of 0.75 and 0.5 from incremental exercise, (ii) compare DFAα1 thresholds with DFAα1 measures during constant-speed running near the maximal lactate steady state (MLSS), and (iii) assess the repeatability of DFAα1 between MLSS trials. Twelve runners performed an incremental running test and constant-speed running 5% below, at, and 5% above the MLSS, plus a repeat trial at MLSS. During 30-min running trials near MLSS, DFAα1 responses were variable (i.e., 0.27-1.24) and affected by intensity (p = 0.031) and duration (p = 0.003). No difference in DFAα1 was detected between MLSS trials (p = 0.597). In the early phase (~ 8 min), DFAα1 measures at MLSS (0.71 [0.13]) remained higher than the DFAα1 identified at RCP from the incremental test (0.57 [0.13]; p = 0.024). In addition, following ~ 18 min of constant speed running at MLSS, DFAα1 measures (0.64 [0.14]) remained higher than 0.5 (p = 0.011)-the value thought to demarcate the boundaries between heavy and severe exercise intensities. Accordingly, using fixed DFAα1 values associated with the RCP from incremental exercise to guide constant-speed exercise training may produce a greater than expected exercise intensity, however; the dependency of DFAα1 on intensity and duration suggest its potential utility to quantify systemic perturbations imposed by continuous exercise.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of sprint interval training on post-fatigue mitochondrial rate in professional boxers. 短跑间歇训练对职业拳击运动员疲劳后线粒体速率的影响。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2024-09-03 DOI: 10.1007/s00421-024-05594-0
Andrew Usher, John Babraj
{"title":"Impact of sprint interval training on post-fatigue mitochondrial rate in professional boxers.","authors":"Andrew Usher, John Babraj","doi":"10.1007/s00421-024-05594-0","DOIUrl":"https://doi.org/10.1007/s00421-024-05594-0","url":null,"abstract":"<p><strong>Purpose: </strong>Professional boxing is a sport that requires a high aerobic capacity to prevent fatigue and allow athletes to perform over 4-12 rounds. Typically, athletes will go into a heavy training period in a pre-bout camp lasting 6 to 9 weeks. This study investigates the impact of 3 weeks of repeated Wingate sprint interval training, performed on standard gym ergometer bikes, on skeletal muscle endurance and mitochondrial function.</p><p><strong>Methods: </strong>Ten male professional boxers (age: 26 ± 4 years, height: 175 ± 5 cm, weight: 70 ± 5 kg) participated in the study. Baseline testing involved a NIRS monitor attached to the rectus femoris muscle prior to an incremental time to exhaustion test on a treadmill. After the treadmill test participants underwent a series of arterial occlusions to determine mitochondrial function post-volitional exhaustion. Participants then continued their own training for 3 weeks and then repeated baseline testing. After the second testing session, participants undertook three weekly sprint sessions consisting of 3 × 30 s maximal sprints with 60 s recovery. Testing was repeated 3 weeks later.</p><p><strong>Results: </strong>The time to exhaustion increased by > 6% after 3 weeks of sprint interval training as compared to baseline and control (p < 0.05). Skeletal muscle oxygen saturation (SmO<sub>2</sub>) at exhaustion was increased by 5.5% after 3 weeks of sprint interval training as compared to baseline and control (p = 0.008). Skeletal muscle mitochondrial rate post exhaustion was increased by 160% after 3 weeks of sprint interval training as compared to baseline and control (p < 0.001).</p><p><strong>Conclusion: </strong>The study demonstrated that SIT led to increased incremental time to exhaustion, higher SmO<sub>2</sub> levels at volitional exhaustion and increased mitochondrial rates in professional boxers. These findings suggest that SIT should be an integral part of a boxe's conditioning regimen to improve performance and safety within the ring.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Resistance training‑induced changes in muscle proteolysis and extracellular matrix remodeling biomarkers in the untrained and trained states. 更正:阻力训练诱导的肌肉蛋白质分解和细胞外基质重塑生物标志物在未训练和训练状态下的变化。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2024-09-01 DOI: 10.1007/s00421-024-05511-5
Maíra C Scarpelli, João G A Bergamasco, Joshua S Godwin, Paulo H C Mesquita, Talisson S Chaves, Deivid G Silva, Diego Bittencourt, Nathalia F Dias, Ricardo A Medalha Junior, Paulo C Carello Filho, Vitor Angleri, Luiz A R Costa, Andreas N Kavazis, Carlos Ugrinowitsch, Michael D Roberts, Cleiton A Libardi
{"title":"Correction to: Resistance training‑induced changes in muscle proteolysis and extracellular matrix remodeling biomarkers in the untrained and trained states.","authors":"Maíra C Scarpelli, João G A Bergamasco, Joshua S Godwin, Paulo H C Mesquita, Talisson S Chaves, Deivid G Silva, Diego Bittencourt, Nathalia F Dias, Ricardo A Medalha Junior, Paulo C Carello Filho, Vitor Angleri, Luiz A R Costa, Andreas N Kavazis, Carlos Ugrinowitsch, Michael D Roberts, Cleiton A Libardi","doi":"10.1007/s00421-024-05511-5","DOIUrl":"10.1007/s00421-024-05511-5","url":null,"abstract":"","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141327337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A scoping review of the effect of chronic stretch training on sleep quality in people with sleep disorders. 慢性拉伸训练对睡眠障碍患者睡眠质量影响的范围界定研究。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2024-09-01 Epub Date: 2024-06-26 DOI: 10.1007/s00421-024-05541-z
Alimoradi Mohammad, Hosseini Elham, Konrad Andreas
{"title":"A scoping review of the effect of chronic stretch training on sleep quality in people with sleep disorders.","authors":"Alimoradi Mohammad, Hosseini Elham, Konrad Andreas","doi":"10.1007/s00421-024-05541-z","DOIUrl":"10.1007/s00421-024-05541-z","url":null,"abstract":"<p><strong>Purpose: </strong>The widespread and health-detrimental sleep disorders have resulted in stretching exercises being investigated as a non-drug solution for enhanced sleep quality. However, a comprehensive understanding of the impact of stretching exercises on individuals with sleep disorders is lacking.</p><p><strong>Methods: </strong>This scoping review systematically maps the existing literature and identifies research gaps on the impact of stretching exercises on sleep quality in individuals with sleep disorders.</p><p><strong>Results: </strong>Sixteen eligible studies were included, where the weighted mean changes indicate a positive trend in sleep quality improvement, ranging from trivial to very large magnitudes. However, concerning the individual study results only 5 out of 16 studies reported significant improvements. Notable enhancements include a small 1.22% overall sleep quality improvement, a large 6.51% reduction in insomnia severity, a large 8.88% increase in sleep efficiency, a moderate 4.36% decrease in sleep onset latency, a large 8.27% decrease in wake after sleep onset, and a very large 14.70% improvement in total sleep time. Trivial changes are noted in sleep duration (0.58%), sleep disturbance reduction (0.07%), and daytime dysfunction reduction (0.19%). Likely mechanisms for the improvement of sleep include autonomic nervous system modulation, muscle tension relief, cortisol regulation, enhanced blood circulation, and psychological benefits such as stress reduction and mood enhancement.</p><p><strong>Conclusion: </strong>There is little evidence that stretching exercises positively impact sleep quality in individuals with sleep disorders. Additionally, further research is vital for designing optimal protocols, understanding of the long-term effects, and clarification of the mechanisms.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of static and dynamic stretching on deep fascia stiffness: a randomized, controlled cross-over study. 静态和动态拉伸对深筋膜僵硬的影响:随机对照交叉研究。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2024-09-01 Epub Date: 2024-04-30 DOI: 10.1007/s00421-024-05495-2
Konstantin Warneke, Thomas Rabitsch, Patrik Dobert, Jan Wilke
{"title":"The effects of static and dynamic stretching on deep fascia stiffness: a randomized, controlled cross-over study.","authors":"Konstantin Warneke, Thomas Rabitsch, Patrik Dobert, Jan Wilke","doi":"10.1007/s00421-024-05495-2","DOIUrl":"10.1007/s00421-024-05495-2","url":null,"abstract":"<p><strong>Aim: </strong>Previous stretching studies mostly investigated effects on the skeletal muscle but comprehensive explorations regarding the role of the connective tissue are scarce. Since the deep fascia has been demonstrated to be sensitive to mechanical tension, it was hypothesized that the fascia would also respond to stretching, contributing to enhanced range of motion (ROM).</p><p><strong>Methods: </strong>Forty (40) recreationally active participants (male: n = 25, female: n = 15) were included in the randomized controlled cross-over trial and allocated to different groups performing 5 min static (STAT) or dynamic (DYN) plantar flexor stretching or control condition (CC) in a random order. Pre- and immediately post-intervention, muscle and fascia stiffness, as well as muscle and fascia thickness were measured using high-resolution ultrasound and strain elastography. ROM was assessed in the ankle joint via the knee to wall test (KtW) and goniometer.</p><p><strong>Results: </strong>STAT reduced both, muscle and fascia stiffness (d = 0.78 and 0.42, p < 0.001, respectively), while DYN did not reduce stiffness compared to the control condition (p = 0.11-0.41). While both conditions showed significant increases in the KtW (d = 0.43-0.46, p = 0.02-0.04), no significant differences to the CC were observed for the isolated ROM testing (p = 0.09 and 0.77). There was a small correlation between fascia stiffness decreases and ROM increases (r = - 0.25, p = 0.006) but no association was found between muscle stiffness decreases and ROM increases (p = 0.13-0.40).</p><p><strong>Conclusion: </strong>Our study is the first to reveal stretch-induced changes in fascia stiffness. Changes of fascia`s but not muscle`s mechanical properties may contribute to increased ROM following stretching.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age-related effects of neuromuscular fatigue and acute recovery responses on maximal and rapid torque measures of the leg extensors and flexors. 与年龄有关的神经肌肉疲劳和急性恢复反应对腿部伸肌和屈肌最大扭矩和快速扭矩测量的影响。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2024-09-01 Epub Date: 2024-05-03 DOI: 10.1007/s00421-024-05493-4
Brennan J Thompson, Eric C Conchola, Kimberly A Clevenger
{"title":"Age-related effects of neuromuscular fatigue and acute recovery responses on maximal and rapid torque measures of the leg extensors and flexors.","authors":"Brennan J Thompson, Eric C Conchola, Kimberly A Clevenger","doi":"10.1007/s00421-024-05493-4","DOIUrl":"10.1007/s00421-024-05493-4","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the effects of neuromuscular fatigue and recovery on maximal and rapid torque characteristics in young and old men for the leg extensors and flexors.</p><p><strong>Methods: </strong>Twenty-one young (age = 24.8 years) and 19 old (72.1 years) men performed maximal voluntary contractions (MVCs) before and at 0, 7, 15, and 30 min following an intermittent submaximal fatigue task. Outcome measures included endurance time, maximal (peak torque; PT) and rapid (absolute and normalized rate of torque development; RTD and nRTD) torque characteristics.</p><p><strong>Results: </strong>The old men had greater endurance times than the young men. Differential recovery patterns were observed for PT, and early and late RTD phases between the leg extensor and flexor muscle groups such that the early rapid torque variables and the flexors demonstrated slower recovery compared to later rapid torque variables and the extensors. The normalized RTD variables were reduced less after the fatigue task and differential muscle and age effects were observed where the flexors were reduced more at the early phase (nRTD1/6) compared to the extensors, however, for the later phase (nRTD2/3) the young men exhibited a greater reduction compared to the old men.</p><p><strong>Conclusions: </strong>Dissimilar fatigue recovery patterns across different phases of RTD, lower limb muscles, and age groups may have important fatigue-related performance and injury risk implications across the adult lifespan.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unfolding the role of exercise in the management of sleep disorders. 揭示运动在治疗睡眠障碍中的作用。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2024-09-01 Epub Date: 2024-07-20 DOI: 10.1007/s00421-024-05556-6
Christoforos D Giannaki, Giorgos K Sakkas, Georgios M Hadjigeorgiou, Mauro Manconi, Panagiotis Bargiotas
{"title":"Unfolding the role of exercise in the management of sleep disorders.","authors":"Christoforos D Giannaki, Giorgos K Sakkas, Georgios M Hadjigeorgiou, Mauro Manconi, Panagiotis Bargiotas","doi":"10.1007/s00421-024-05556-6","DOIUrl":"10.1007/s00421-024-05556-6","url":null,"abstract":"<p><p>Sleep disorders are prevalent among the general population and even more in individuals suffering from chronic diseases. Recent data reveal promising effects of physical exercise as a non-pharmacological approach for improving sleep and managing various sleep disorders. However, more studies with proper design and methodology should be conducted in the future to obtain a clearer understanding of the subject. The role of exercise in preventing and improving sleep disorders is probably much higher than what is currently exploited. To fully exploit the potential benefit of physical activity on sleep disorders in the future, it is necessary to identify the relevant tools to assess sleep-wake disorders and establish specific exercise protocols tailored to different sleep disorders. The present manuscript aims to review the literature on the use of exercise in managing selected sleep disorders. Regular exercise, including short-term aerobic activity, resistance training, and mind-body exercises, can effectively improve sleep quality, particularly in cases of insomnia and sleep-disordered breathing. Additionally, increasing evidence supports the effectiveness of aerobic and strength training, and body-mind exercises such as yoga in managing sleep-related movement disorders. Exercise can be a safe, affordable, and efficient tool in enhancing sleep quality and improving sleep disorders. Per se, regular exercise could play an adjuvant role alongside with established therapies, or a valid alternative when the pharmacological approach is limited by side effects, interactions, or inefficacy. More research is needed to define how exercise affects the physiology of sleep, and consequently how to use exercise in patients with sleep disorders.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141731091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of chronotropic incompetence on physiologic responses during progressive exercise in people with Parkinson's disease. 帕金森病患者在进行渐进式运动时,时相失调对生理反应的影响。
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2024-09-01 Epub Date: 2024-04-29 DOI: 10.1007/s00421-024-05492-5
Tone Ricardo Benevides Panassollo, Sue Lord, Usman Rashid, Denise Taylor, Grant Mawston
{"title":"The effect of chronotropic incompetence on physiologic responses during progressive exercise in people with Parkinson's disease.","authors":"Tone Ricardo Benevides Panassollo, Sue Lord, Usman Rashid, Denise Taylor, Grant Mawston","doi":"10.1007/s00421-024-05492-5","DOIUrl":"10.1007/s00421-024-05492-5","url":null,"abstract":"<p><strong>Purpose: </strong>Heart rate (HR) response is likely to vary in people with Parkinson's disease (PD), particularly for those with chronotropic incompetence (CI). This study explores the impact of CI on HR and metabolic responses during cardiopulmonary exercise test (CPET) in people with PD, and its implications for exercise intensity prescription.</p><p><strong>Methods: </strong>Twenty-eight participants with mild PD and seventeen healthy controls underwent CPET to identify the presence or absence of CI. HR and metabolic responses were measured at submaximal (first (VT1) and second (VT2) ventilatory thresholds), and at peak exercise. Main outcome measures were HR, oxygen consumption (VO<sub>2</sub>), and changes in HR responses (HR/WR slope) to an increase in exercise demand.</p><p><strong>Results: </strong>CI was present in 13 (46%) PD participants (PDCI), who during CPET, exhibited blunted HR responses compared to controls and PD non-CI beyond 60% of maximal workload (p ≤ 0.05). PDCI presented a significantly lower HR at VT2, and peak exercise compared to PD non-CI and controls (p ≤ 0.001). VO<sub>2</sub> was significantly lower in PDCI than PD non-CI and controls at VT2 (p = 0.003 and p = 0.036, respectively) and at peak exercise (p = 0.001 and p = 0.023, respectively).</p><p><strong>Conclusion: </strong>Although poorly understood, the presence of CI in PD and its effect on HR and metabolic responses during incremental exercise is significant and important to consider when programming aerobic exercises.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can non-invasive motor unit analysis reveal distinct neural strategies of force production in young with uncomplicated type 1 diabetes? 非侵入性运动单元分析能否揭示无并发症的 1 型糖尿病患者的不同发力神经策略?
IF 2.8 3区 医学
European Journal of Applied Physiology Pub Date : 2024-08-30 DOI: 10.1007/s00421-024-05595-z
Giacomo Valli, Rui Wu, Dean Minnock, Giuseppe Sirago, Giosuè Annibalini, Andrea Casolo, Alessandro Del Vecchio, Luana Toniolo, Elena Barbieri, Giuseppe De Vito
{"title":"Can non-invasive motor unit analysis reveal distinct neural strategies of force production in young with uncomplicated type 1 diabetes?","authors":"Giacomo Valli, Rui Wu, Dean Minnock, Giuseppe Sirago, Giosuè Annibalini, Andrea Casolo, Alessandro Del Vecchio, Luana Toniolo, Elena Barbieri, Giuseppe De Vito","doi":"10.1007/s00421-024-05595-z","DOIUrl":"https://doi.org/10.1007/s00421-024-05595-z","url":null,"abstract":"<p><strong>Purpose: </strong>to investigate the early consequences of type 1 diabetes (T1D) on the neural strategies of muscle force production.</p><p><strong>Methods: </strong>motor unit (MU) activity was recorded from the vastus lateralis muscle with High-Density surface Electromyography during isometric knee extension at 20 and 40% of maximum voluntary contraction (MVC) in 8 T1D (4 males, 4 females, 30.5 ± 3.6 years) and 8 matched control (4 males, 4 females, 27.3 ± 5.9 years) participants. Muscle biopsies were also collected from vastus lateralis for fiber type analysis, including myosin heavy chain (MyHC) isoform content via protein and mRNA expression.</p><p><strong>Results: </strong>MVC was comparable between groups as well as MU conduction velocity, action potentials' amplitude and proportions of MyHC protein isoforms. Nonetheless, MU discharge rate, relative derecruitment thresholds and mRNA expression of MyHC isoform I were lower in T1D.</p><p><strong>Conclusions: </strong>young people with uncomplicated T1D present a different neural control of muscle force production. Furthermore, differences are detectable non-invasively in absence of any functional manifestation (i.e., force production and fiber type distribution). These novel findings suggest that T1D has early consequences on the neuromuscular system and highlights the necessity of a better characterization of neural control in this population.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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