European Journal of Ophthalmology最新文献_第5页

Transition programmes for children moving from paediatric to adult eye care services: A scoping review. 儿童从儿科到成人眼保健服务的过渡方案：范围审查。

IF 1.3 4区医学

European Journal of Ophthalmology Pub Date : 2026-11-01 Epub Date: 2026-06-19 DOI: 10.1177/11206721261462355

Ameeta Kumar, Shiama Balendra, Desta Bokre, Annegret H Dahlmann-Noor

{"title":"Transition programmes for children moving from paediatric to adult eye care services: A scoping review.","authors":"Ameeta Kumar, Shiama Balendra, Desta Bokre, Annegret H Dahlmann-Noor","doi":"10.1177/11206721261462355","DOIUrl":"10.1177/11206721261462355","url":null,"abstract":"PurposeFor young people, transition programmes between paediatric and adult services ensure continuity of care for young people while improving their confidence and autonomy in managing their health. Despite targeted support improving outcomes in other chronic conditions, the development of transition programmes in children's eye care remains limited. This scoping review aims to review published literature about transition programmes supporting young people in ophthalmic services.MethodsFollowing guidance from the Joanna Briggs Institute, we carried out a scoping review, searching Ovid MEDLINE, Ovid Embase and Cochrane Library databases to identify articles on transition programmes for young people from paediatric to adult eye care services. Two reviewers independently screened the titles and abstracts before reviewing the full text. We extracted data into a pre-specified extraction tool.ResultsOf 339 identified publications, five met the inclusion criteria. No publications specifically addressed transition programmes in ophthalmology. The included studies reported ophthalmic care within the context of systemic conditions. Two studies reported a transition programme for young people with type 1 diabetes, two rheumatological conditions, and one explored young people's views on the transition process in an eye/vision context.ConclusionThis review highlights the scarcity of reports about transition programmes relating to ophthalmology. Existing programmes in other specialities can provide a framework which could be adapted to ophthalmology. Further research is required to develop the use and impact of programmes in ophthalmology to ensure better outcomes for patients and healthcare providers.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1504-1511"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148276565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "Long-term surgical outcomes of primary silicone orbital implant after orbital evisceration in infectious versus non-infectious cases". 对“感染性与非感染性眼眶摘除术后一期硅胶眼眶植入的远期手术效果”的评论。

IF 1.3 4区医学

European Journal of Ophthalmology Pub Date : 2026-10-27 DOI: 10.1177/11206721261445280

Rupendra Chandrakar, Chandreshwar Prasad Sinha, Shrikant Naik

引用次数: 0

Selective preoperative evaluation in cataract surgery reduces costs, carbon footprint and time burden: A triple bottom line analysis. 选择性白内障手术术前评估降低成本，碳足迹和时间负担：三重底线分析。

IF 1.3 4区医学

European Journal of Ophthalmology Pub Date : 2026-10-24 DOI: 10.1177/11206721261501708

J Pascual-Prieto, B Burgos-Blasco, C Nieto-Gómez, S Alvarez-Gallego, J García-Feijoo

{"title":"Selective preoperative evaluation in cataract surgery reduces costs, carbon footprint and time burden: A triple bottom line analysis.","authors":"J Pascual-Prieto, B Burgos-Blasco, C Nieto-Gómez, S Alvarez-Gallego, J García-Feijoo","doi":"10.1177/11206721261501708","DOIUrl":"https://doi.org/10.1177/11206721261501708","url":null,"abstract":"PurposeTo evaluate the economic, environmental and social impact of selective versus routine preoperative evaluation in cataract surgery using a Triple Bottom Line (TBL) framework, and to assess whether selective testing affects perioperative safety outcomes.MethodsObservational comparative study including 1,519 patients (1,944 surgeries): a Routine Testing group (RT: 822 patients, 1,035 surgeries) and a Selective Testing group (ST: 697 patients, 909 surgeries). Preoperative evaluation in the ST group was reserved for patients with severe unstable systemic disease, inability to cooperate, or intolerance to the supine position. Economic, environmental and social outcomes were derived from hospital analytical accounting, a hybrid life cycle assessment, and a mobility survey.ResultsIntraoperative complication rates (2.71% vs 1.65%; OR 1.65, 95% CI 0.88-3.12) and surgical cancellations (1.83% vs 1.43%; OR 1.28, 95% CI 0.63-2.62) did not differ significantly between groups. The ST model reduced mean total cost per surgery from €101.71 to €46.88, carbon footprint from 33.92 to 15.63 kgCO2e, and preoperative time burden from 125.31 to 57.75 min, with an estimated productivity saving exceeding €33,000.ConclusionsSelective preoperative evaluation was not associated with a statistically significant increase in intraoperative complications or cancellations while delivering meaningful economic, environmental and social benefits, supporting its broader adoption in line with current clinical guidelines.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261501708"},"PeriodicalIF":1.3,"publicationDate":"2026-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149264580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benign lobular inner nuclear layer proliferation associated with congenital hypertrophy of the retinal pigment epithelium. 良性小叶内核层增生伴先天性视网膜色素上皮肥大。

IF 1.3 4区医学

European Journal of Ophthalmology Pub Date : 2026-10-23 DOI: 10.1177/11206721261501707

Erdoğan Yaşar, Mustafa Değer Bilgeç, Saadet Gültekin Irgat, Orhan Altunel, Fatih Özcura

引用次数: 0

Fern-like corneal neovascularisation in end-stage neovascular glaucoma. 终末期新生血管性青光眼的蕨类角膜新生血管化。

IF 1.3 4区医学

European Journal of Ophthalmology Pub Date : 2026-10-22 DOI: 10.1177/11206721261501699

Vijayalakshmi A Senthilkumar, Aditi Vijay Bhosale

引用次数: 0

Apoptotic, oxidative stress, and endothelial signaling protein expression in lens epithelial cells of patients with pseudoexfoliation syndrome. 假性脱落综合征患者晶状体上皮细胞的凋亡、氧化应激和内皮信号蛋白表达。

IF 1.3 4区医学

European Journal of Ophthalmology Pub Date : 2026-10-21 DOI: 10.1177/11206721261499891

Kuddusi Teberik, Ilker Kiliccioglu, Bayram Meydan, Gorkem Dulger

{"title":"Apoptotic, oxidative stress, and endothelial signaling protein expression in lens epithelial cells of patients with pseudoexfoliation syndrome.","authors":"Kuddusi Teberik, Ilker Kiliccioglu, Bayram Meydan, Gorkem Dulger","doi":"10.1177/11206721261499891","DOIUrl":"https://doi.org/10.1177/11206721261499891","url":null,"abstract":"PurposePseudoexfoliation syndrome (PXS) is associated with increased lens epithelial cell apoptosis; however, the underlying molecular mechanisms at the protein level remain unclear. This study aimed to investigate apoptotic, nitric oxide, and endothelial signaling-related protein expression (Caspase-3, -8, -9, eNOS, and VEGF-B) in anterior lens capsule epithelial cells of PXS patients and age-matched controls.MethodsIn this prospective comparative study, anterior lens capsule specimens were obtained from 55 patients with PXS and 30 age-matched cataract controls during phacoemulsification surgery. PXS severity was graded (Grades 1-3) based on slit-lamp biomicroscopic findings. Caspase-3, Caspase-8, Caspase-9, eNOS, and VEGF-B protein levels were measured by ELISA. Marker levels were compared between PXS and control groups and further analyzed according to disease grade (Grades 1-3) within the PXS group.ResultsNo significant differences were observed between groups in age, gender distribution, cataract type, visual acuity, or intraocular pressure. Caspase-3, Caspase-9, VEGF-B, and eNOS levels were significantly higher in the PXS group compared to controls (P < 0.001). Caspase-8 levels did not differ significantly between groups (P = 0.711). In grade-based analysis, Caspase-3, Caspase-8, Caspase-9, and VEGF-B levels increased progressively from Grade 1 to Grade 3 (all P ≤ 0.003). In contrast, eNOS showed a decreasing profile across grades, with a significant reduction in Grade 3 versus Grade 1 (P = 0.01).ConclusionPXS is associated with significant alterations in apoptosis-related, nitric oxide-related, and endothelial signaling proteins in lens epithelial cells, with a distinct grade-dependent molecular pattern. These findings identify Caspase-3, Caspase-9, VEGF-B, and eNOS as potential severity-associated biomarkers and therapeutic targets in PXS pathogenesis.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261499891"},"PeriodicalIF":1.3,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual and anatomical outcomes of early versus delayed anti-VEGF switching after bevacizumab loading in diabetic macular oedema. 糖尿病黄斑水肿患者贝伐单抗负荷后早期与延迟抗vegf转换的视觉和解剖学结果

IF 1.3 4区医学

European Journal of Ophthalmology Pub Date : 2026-10-19 DOI: 10.1177/11206721261499885

Rukiye Kilic Ucgul, Kemal Tekin, Dogukan Temel, Furkan Karagoz, Busra Turpcuoglu, Merve Inanc Tekin, Kuddusi Teberik

{"title":"Visual and anatomical outcomes of early versus delayed anti-VEGF switching after bevacizumab loading in diabetic macular oedema.","authors":"Rukiye Kilic Ucgul, Kemal Tekin, Dogukan Temel, Furkan Karagoz, Busra Turpcuoglu, Merve Inanc Tekin, Kuddusi Teberik","doi":"10.1177/11206721261499885","DOIUrl":"https://doi.org/10.1177/11206721261499885","url":null,"abstract":"PurposeTo compare 24-month visual and anatomical outcomes associated with early versus delayed switching from bevacizumab in treatment-naive eyes with center-involving diabetic macular edema (DME) and suboptimal early response.MethodsThis retrospective cohort included 87 eyes with inadequate response (<5 ETDRS-letter gain and/or <20% central macular thickness [CMT] reduction) after three monthly bevacizumab injections. In a month-3 landmark analysis, eyes were classified by the month-3 treatment decision as immediate switch (n = 37) or continued bevacizumab with later switching (n = 50). An observed-timing comparison excluded eyes switched at months 4-5 (n = 7) and compared early switch (month 3; n = 37) with delayed switch (month ≥6; n = 43) to aflibercept 2 mg or ranibizumab. Outcomes from the month-3 decision point were evaluated using adjusted mixed-effects models with categorical time.ResultsAt month 3, BCVA (0.42 versus 0.45 logMAR) and CMT (437 versus 408 µm) were similar in the early- and delayed-switch groups. In the landmark analysis, adjusted 24-month differences were -0.07 logMAR (95% CI, -0.17 to 0.03; P = 0.171), equivalent to 3.5 ETDRS letters favoring immediate switching (95% CI, -1.5 to 8.5), and -36 µm (95% CI, -71 to -1; P = 0.044). In the observed-timing comparison, they were -0.08 logMAR (4.0 letters; 95% CI, -1.5 to 9.5; P = 0.154) and -39 µm (95% CI, -77 to -1; P = 0.044). A ≥ 20% CMT reduction at month 24 occurred in 62.2% versus 37.2%. Total injections numbered 11.2 ± 2.4 versus 14.5 ± 2.6.ConclusionsEarlier switching was associated with greater anatomical improvement in both analyses. A 24-month visual advantage was not demonstrated, although a clinically meaningful benefit could not be excluded.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261499885"},"PeriodicalIF":1.3,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Commentary on: "Optimizing topical glaucoma treatment outcomes: When less is better. A review on the clinical benefits of reducing treatment burden in glaucoma management". 评论：“优化局部青光眼治疗效果：越少越好。减轻青光眼治疗负担的临床获益综述。

IF 1.3 4区医学

European Journal of Ophthalmology Pub Date : 2026-10-16 DOI: 10.1177/11206721261473757

Louis Arnould

引用次数: 0

Adult presentation of a congenital zonular cataract. 成人一例先天性带状白内障。

IF 1.3 4区医学

European Journal of Ophthalmology Pub Date : 2026-10-14 DOI: 10.1177/11206721261499882

Aayush Majumdar, Vibha Dhiman

引用次数: 0

Pretreatment MRI radiomics for predicting recurrence and metastasis after hypofractionated stereotactic radiosurgery in uveal melanoma. 预处理MRI放射组学预测葡萄膜黑色素瘤低分割立体定向放射手术后复发和转移。

IF 1.3 4区医学

European Journal of Ophthalmology Pub Date : 2026-10-12 DOI: 10.1177/11206721261495745

Yusuf Baytar, Firat Atak, Gozde Yazici, Irem Koc, Hayyam Kiratli, Elif Gunay Bulut

{"title":"Pretreatment MRI radiomics for predicting recurrence and metastasis after hypofractionated stereotactic radiosurgery in uveal melanoma.","authors":"Yusuf Baytar, Firat Atak, Gozde Yazici, Irem Koc, Hayyam Kiratli, Elif Gunay Bulut","doi":"10.1177/11206721261495745","DOIUrl":"https://doi.org/10.1177/11206721261495745","url":null,"abstract":"PurposeTo develop and internally evaluate pretreatment MR-based radiomics models for predicting local recurrence and metastasis after hypofractionated stereotactic radiosurgery (SRS) for uveal melanoma.MethodsThis retrospective study analyzed pretreatment MRI (T1-weighted, T2-weighted, contrast-enhanced T1-weighted) of 88 SRS-treated UM patients. Tumors were segmented on the axial slice with the greatest cross-sectional area, and 854 radiomic features were extracted for each sequence. After inter-observer reproducibility filtering (ICC ≥ 0.80) and elastic-net feature selection, separate Gaussian Naive Bayes models for local recurrence and metastasis were developed using the retained features with a 70:30 train-test split. SMOTE was applied within training folds to address class imbalance. Held-out test set performance was assessed using AUC, F1 score, accuracy, sensitivity, specificity, and predictive values.ResultsThe local-recurrence model achieved an AUC of 0.958, accuracy of 0.889, sensitivity of 1.00 (3/3), and specificity of 0.875 (21/24). The metastasis model showed limited discrimination (AUC, 0.528; accuracy, 0.815; sensitivity, 0.333 [1/3]; specificity, 0.875 [21/24]). Among three-fraction treatments, a total dose >45 Gy was associated with less local recurrence (p = 0.010), whereas no other clinical variable was significantly associated with either outcome.ConclusionMRI radiomics showed promising discrimination for local recurrence but limited discrimination for metastasis. These findings should be interpreted with caution given the small number of events in the test set and warrant external validation in larger cohorts.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261495745"},"PeriodicalIF":1.3,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0