European Journal of Ophthalmology最新文献_第5页

Characteristics of submacular hemorrhage with bacillary layer detachment and intrabacillary hemorrhage. 白膜下出血伴乳头层脱落和毛细血管内出血的特征。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2024-11-15 DOI: 10.1177/11206721241300204

Ayushi Choudhary, Saloni Kapoor, Gaurang Sehgal, Priyanka Gandhi, Rupal Kathare, Vishma Prabhu, Prathiba Hande, Naresh Kumar Yadav, Jay Chhablani, Ramesh Venkatesh

{"title":"Characteristics of submacular hemorrhage with bacillary layer detachment and intrabacillary hemorrhage.","authors":"Ayushi Choudhary, Saloni Kapoor, Gaurang Sehgal, Priyanka Gandhi, Rupal Kathare, Vishma Prabhu, Prathiba Hande, Naresh Kumar Yadav, Jay Chhablani, Ramesh Venkatesh","doi":"10.1177/11206721241300204","DOIUrl":"10.1177/11206721241300204","url":null,"abstract":"PurposeTo study the outcomes of patients presenting with submacular hemorrhage (SMH) and bacillary layer detachment (BALAD) following intervention.MethodsThis retrospective study examined fundus photographs and optical coherence tomography (OCT) scans to identify treatment-naive SMH and BALAD cases. Two groups were formed: SMH cases with and without BALAD. The treatment outcomes of these cases were assessed.ResultsThirteen (65%) of the 20 eyes with SMH had BALAD. Blunt trauma was the most common cause of SMH (n = 10, 50%). Median age was 46 years (IQR range: 28-70). Demographic, clinical, or OCT imaging findings between the groups (p > 0.05) were comparable. Nine (45%) patients each underwent intravitreal gas injection alone or along with PPV and TpA injection. At 1-month post-treatment, VA improved (logMAR VA - 0.89; p = 0.017). BALADs and intrabacillary hemorrhage had resolved in eight (61%) cases. Intraretinal, subretinal, and sub-RPE fluids resolved in 100%, 70%, and 43% of cases, respectively. Eyes with resolved BALAD showed greater improvement in VA (logMAR VA - 0.98) than eyes with persisting BALAD (logMAR VA - 1.1) and resulted in significant decrease in central macular (p = 0.016) and retinal thicknesses (p = 0.031). SMH eyes without pre-treatment BALAD also observed statistically significant improvement in visual acuity following intervention (p = 0.031).ConclusionBALAD and intrabacillary hemorrhage in SMH are relatively common. A significant proportion of cases had their BALAD and intrabacillary haemorrhage resolved following treatment. Persistence of BALAD had no effect on VA.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1349-1357"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142617365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mental burden of ocular surface discomfort. 眼表不适的精神负担。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2024-12-18 DOI: 10.1177/11206721241305661

Antonio Di Zazzo, Chiara De Gregorio, Sara Spelta, Senol Demircan

引用次数: 0

Microvascular changes after proton beam radiotherapy for iris melanoma: An optical coherence tomography angiography study. 虹膜黑色素瘤质子束放疗后微血管变化：光学相干断层扫描血管造影研究。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2025-03-13 DOI: 10.1177/11206721251319822

Matteo Fallico, Antonio Longo, Teresio Avitabile, Pietro Alosi, Edoardo Dammino, Michele Reibaldi, Paola Marolo, Guglielmo Parisi, Niccolò Castellino, Vincenza Bonfiglio, Rosario Caltabiano, Giuseppe Broggi, Pietro Foti, Corrado Spatola, Marco Ragusa, Cristina Barbagallo, Enrico Borrelli, Andrea Russo

{"title":"Microvascular changes after proton beam radiotherapy for iris melanoma: An optical coherence tomography angiography study.","authors":"Matteo Fallico, Antonio Longo, Teresio Avitabile, Pietro Alosi, Edoardo Dammino, Michele Reibaldi, Paola Marolo, Guglielmo Parisi, Niccolò Castellino, Vincenza Bonfiglio, Rosario Caltabiano, Giuseppe Broggi, Pietro Foti, Corrado Spatola, Marco Ragusa, Cristina Barbagallo, Enrico Borrelli, Andrea Russo","doi":"10.1177/11206721251319822","DOIUrl":"10.1177/11206721251319822","url":null,"abstract":"PurposeTo evaluate macular and peripapillary microvascular changes after proton beam radiotherapy for iris melanoma using optical coherence tomography angiography (OCT-A).MethodsPatients treated with proton beam radiotherapy for iris melanoma were included in the iris melanoma group. Fellow eyes were used as controls. Vessel density (VD) of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) of the macula, radial peripapillary capillary plexus (RPCP) and foveal avascular zone (FAZ) were evaluated using OCT-A. Central macular thickness (CMT) and nerve fiber layer thickness (RNFL) were also investigated.ResultsA total of 11 patients were included. Vessel density in the whole SCP was comparable between treated eyes and untreated fellow eyes (p = 0.32). Vessel density in the whole DCP was lower in the iris melanoma group compared with untreated fellow eyes: 39% [standard deviation (SD) 1.9] versus 49% (SD 4.1), respectively (p < 0.001). Vessel density of the whole RPCP was lower in the iris melanoma group compared with untreated fellow eyes: 44% (SD 3.5) versus 48% (SD 2.2), respectively (p = 0.02). No differences between treated eyes and untreated fellow eyes were noted when evaluating FAZ, CMT and RNFL thickness.ConclusionIrradiation of the iris may determine vascular damage in the uveal tract, which, consequently, can affect the retinal vascular network. Changes in OCT-A parameters detected in DCP and RPCP may be early signs of microvascular impairment in these patients.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1382-1388"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of diplopia masquerading as ptosis: Unveiling a hidden clival chordoma. 伪装为上睑下垂的复视1例：揭露隐藏的斜坡脊索瘤。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2025-03-13 DOI: 10.1177/11206721251323631

Neslihan Sevimli, Güneş Taydaş, Beril Aycan Yağız

引用次数: 0

Evaluation of intraocular pressure and mean ocular perfusion pressure changes following intravitreal anti-VEGF injections. 玻璃体内注射抗vegf后眼压和平均眼灌注压变化的评价。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2025-02-21 DOI: 10.1177/11206721251318773

Benedetta Colizzi, Dario Romano, Sofia Lunardon, Lorenzo Sabbatini, Luca Mario Rossetti

{"title":"Evaluation of intraocular pressure and mean ocular perfusion pressure changes following intravitreal anti-VEGF injections.","authors":"Benedetta Colizzi, Dario Romano, Sofia Lunardon, Lorenzo Sabbatini, Luca Mario Rossetti","doi":"10.1177/11206721251318773","DOIUrl":"10.1177/11206721251318773","url":null,"abstract":"ObjectiveTo evaluate changes in intraocular pressure (IOP) and mean ocular perfusion pressure (MOPP) following intravitreal anti-VEGF injections (IVI) and to assess influencing factors.MethodsIn a prospective study, 119 eyes received anti-VEGF IVI, with 60 eyes treated in the supine position and 59 eyes in the seated position. IOP was assessed using an iCare IC200 rebound tonometer before, immediately after, and at 5 and 30 min post-injection. MOPP was calculated at the same time points. Ocular biometric and demographic data were collected to analyze their impact on IOP changes.ResultsIOP increased from 15.76 ± 4.34 mmHg at baseline to 49.79 ± 15.73 immidiately post-IVI, then decreased to 29.96 ± 10.55 at 5 min and 21.80 ± 7.36 at 30 min. MOPP dropped from 54.02 ± 10.7 mmHg to 35.7 ± 19.7 mmHg immediately post-IVI, recovering to 40.68 ± 15.9 at 5 min and 51.08 ± 12.2 at 30 min. Supine patients exhibited higher IOP, but maintained higher MOPP compared to seated patients. Only 25% of glaucoma patients returned to baseline IOP within 30 min, compared to 48.9% of non-glaucomatous patients (p = 0.02). Phakic patients have greater IOP changes across time, with significant differences at 5 min (p = 0.03).ConclusionIVI induced IOP increases and MOPP decreases are significant but normalized to baseline +2SD within 30 min in 67.77% and 97.52% of patients. Glaucomatous and phakic patients are at higher risk for prolonged IOP elevation, requiring careful management.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":"35 4","pages":"1272-1279"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prechoroidal cleft changes after intravitreal injections of Faricimab in treatment-naïve and nonresponders-to-aflibercept patients: A case series. 在treatment-naïve和对aflibercept无反应的患者中，玻璃体内注射Faricimab后脉络膜前裂的变化：一个病例系列。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2025-02-26 DOI: 10.1177/11206721251322541

Elisa Stradiotto, Alessandro Feo, Giovanni Ottonelli, Vanessa Ferraro, Claudia Del Turco, Claudio Panico, Mario R Romano, Carlo La Spina

{"title":"Prechoroidal cleft changes after intravitreal injections of Faricimab in treatment-naïve and nonresponders-to-aflibercept patients: A case series.","authors":"Elisa Stradiotto, Alessandro Feo, Giovanni Ottonelli, Vanessa Ferraro, Claudia Del Turco, Claudio Panico, Mario R Romano, Carlo La Spina","doi":"10.1177/11206721251322541","DOIUrl":"10.1177/11206721251322541","url":null,"abstract":"PurposeTo describe the clinical and optical coherence tomography (OCT) changes of prechoroidal cleft in treatment-naïve and non-naïve neovascular age-related macular degeneration (nAMD) treated with Faricimab intravitreal injections.MethodsA case series (4 eyes from 4 patients).ResultsCases 1 and 2 were diagnosed with treatment-naïve nAMD. Case 1 showed minimal prechoroidal cleft persistence after treatment with visual acuity stabilization. Case 2 showed prechoroidal cleft resolution, followed by its recurrence with neovascular reactivation. Cases 3 and 4 had a history of nAMD unresponsive to Aflibercept therapy. In Case 3, prechoroidal cleft reappearance occurred simultaneously to neovascular reactivation. In Case 4 prechoroidal cleft resolved rapidly after switching to Faricimab, but this was complicated by the development of a retinal pigment epithelium (RPE) tear.ConclusionIn this report, we highlight the importance of prechoroidal cleft as a negative prognostic OCT biomarker despite the increasingly proved efficacy of Faricimab. Pigment epithelium detachment height may correlate with the size of prechoroidal cleft and macular neovascularization (MNV) activity. Further studies are needed to better elucidate the prognostic significance of prechoroidal cleft after Faricimab therapy.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"NP16-NP20"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are optic nerve head and choroidal circulation affected by eye movements? 视神经头和脉络膜循环是否受眼球运动的影响？

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2024-11-10 DOI: 10.1177/11206721241298127

Pınar Orenc, Elvan Yalcin

{"title":"Are optic nerve head and choroidal circulation affected by eye movements?","authors":"Pınar Orenc, Elvan Yalcin","doi":"10.1177/11206721241298127","DOIUrl":"10.1177/11206721241298127","url":null,"abstract":"AimAlthough it has been reported that the optic nerve can be mechanically affected by the eye's horizontal movements, studies examining horizontal movements with optical coherence tomography angiography (OCTA) have only recently begun to emerge. This study aimed to investigate whether there are changes in the OCTA data of healthy individuals in the primary gaze, abduction, and adduction.MethodThirty volunteers (15-73 years old) were included in this prospectively designed study. Radial peripapillary capillary density parameters (RPCD) taken with OCTA in cases of primary gaze, abduction, and adduction were examined. With the OCTA device Angio Disc QuickVue that was used in the study, 3 main vessel structures could be examined.ResultIn the patients' primary, abduction, and adduction positions, a difference was observed only in the superior hemifield area of the left eye (P = 0.032). The superior hemifield all vessels vessel densities (AV VD) were 60.1 ± 2.7 in the central gaze, 59.9 ± 2.6 in the adduction, and 60.8 ± 2.6 in the abduction positions, with a relative decrease observed in adduction. This was also related to age. No difference was detected in terms of the other RPCD parameters.ConclusionIn healthy individuals, short-term horizontal eye movements may not result in significant changes except for superior hemifield in OCTA data.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1389-1393"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142617359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quality of vision with monofocal intraocular lens after cataract surgery: Comprehensive evaluation and graphical illustration. 白内障手术后单焦点人工晶状体的视力质量：综合评价和图解。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2024-12-20 DOI: 10.1177/11206721241306156

Jorge Fs Henriques, Marisa A Duarte, Tatiana Sm Queirós, Rita Coimbra, Francisco Caramelo, Andreia Fm Rosa, Conceição L Lobo Fonseca, Joaquim Cn Murta

{"title":"Quality of vision with monofocal intraocular lens after cataract surgery: Comprehensive evaluation and graphical illustration.","authors":"Jorge Fs Henriques, Marisa A Duarte, Tatiana Sm Queirós, Rita Coimbra, Francisco Caramelo, Andreia Fm Rosa, Conceição L Lobo Fonseca, Joaquim Cn Murta","doi":"10.1177/11206721241306156","DOIUrl":"10.1177/11206721241306156","url":null,"abstract":"PurposeTo comprehensively characterize the quality of vision (QV) in an otherwise healthy population undergoing bilateral consecutive cataract surgery with the implantation of a monofocal intraocular lens (IOL) and to propose a graphical illustration.SettingCentro Hospitalar e Universitário de Coimbra, Portugal.DesignCross-sectional study.MethodsThis study included patients that underwent sequential bilateral cataract surgery with implantation of a monofocal acrylic foldable single-piece IOL. Patients were evaluated at the 3rd postoperative month in terms of bilateral uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA) and corrected near visual acuity (CNVA); sphero-cylindrical refraction; bilateral reading speed and contrast sensitivity function (CSF); corneal topography/tomography; aberrometry; pupillometry; negative dysphotopsia (ND); Catquest-9SF and Quality of Vision (QoV) questionnaires.ResultsBoth eyes from 26 (n = 26) consecutive patients with mean age of 68 years ± 6.68 were included. UDVA mean was logMAR = 0.01 ± 0.04, and CDVA was logMAR = 0.00 ± 0.04. The average reading speed was 110.42 words/minute. The CSF showed a descendent curve for higher spatial frequencies and was lower with glare. ND was present in 1.92% of the patients. Catquest-9SF mean was 95.46% and QoV mean score was 4.48 points. A radar graph showing median scores across the multiple variables assessed was produced demonstrating a wide panorama of QV.ConclusionPatients' satisfaction was correlated with CSF, reading speed, CNVA and residual spherical equivalent. To the author's best knowledge, this study establishes, for the first time, a comprehensive panorama of visual performance through a radar graph that can be utilized to describe the QV.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1187-1194"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety and efficacy of a modified suprachoroidal silicone tube shunt implant in primary open angle and pseudo-exfoliative glaucoma. 改良的脉络膜上硅胶管分流术治疗原发性开角型和假剥脱性青光眼的安全性和有效性。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2025-01-22 DOI: 10.1177/11206721251314532

Nikoloz Labauri, Tekla Mamageishvili, Ana Vachiberidze, Monika Zalinian, Lika Svanadze, Luka Sabanadze, Orkhan Huseynov, Tamar Sulkhanishvili, Maka Labauri, Marine Shakarashvili, Mikheil Omiadze, Yoram Solberg

{"title":"Safety and efficacy of a modified suprachoroidal silicone tube shunt implant in primary open angle and pseudo-exfoliative glaucoma.","authors":"Nikoloz Labauri, Tekla Mamageishvili, Ana Vachiberidze, Monika Zalinian, Lika Svanadze, Luka Sabanadze, Orkhan Huseynov, Tamar Sulkhanishvili, Maka Labauri, Marine Shakarashvili, Mikheil Omiadze, Yoram Solberg","doi":"10.1177/11206721251314532","DOIUrl":"10.1177/11206721251314532","url":null,"abstract":"PurposeTo assess the safety and efficacy of a modified suprachoroidal silicone tube (SST) shunt in patients with primary open-angle glaucoma (POAG) and pseudo-exfoliative glaucoma (PXG) in this experimental study.MethodsIn this single-center, retrospective longitudinal data analysis 66 eyes of 59 patients having POAG and PXG were included and treated with modified SST shunt in combination with cataract or as a stand-alone procedure. Pre- and postoperative intraocular pressure (IOP), best corrected visual acuity (BCVA), C/D ratio and ocular adverse events (AEs) were assessed in all participants.ResultsThe average follow-up period was 18.56 ± 7.93 months. Mean baseline IOP reduced from 27.02 ± 5.43 mmHg to 13.23 ± 3.70 mmHg (p < 0.001). Mean number of ocular hypotensive medications reduced from 3.17 ± 0.89 to 1.83 ± 1.44 (p < 0.001). BCVA remained stable in 49 eyes (74.2%) throughout the follow-up period. Mean baseline BCVA of 0.73 ± 0.27 slightly declined to 0.68 ± 0.30 at the final follow-up (p < 0.001). Three adverse events of special interest (AESI) were observed hypotonic maculopathy, anterior chamber inflammation with pupillary membranes, and macular edema. None of these events was related to the SST shunt. Other complications such as intra and early postoperative hyphema in 3 and tube-iris contact causing slight corectopia in 2 cases were noted.ConclusionsThe surgical technique and device studied in this work demonstrated a good safety profile and signal of efficacy. This device may serve as a bridge between minimally invasive glaucoma surgeries (MIGS) and conventional filtering or episcleral tube shunt surgeries. A larger scale prospective trial is planned.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1314-1322"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of mitomycin C on surgical outcomes of PAUL glaucoma implant in neovascular glaucoma: 12-month follow-up results. 丝裂霉素C对PAUL青光眼植入治疗新生血管性青光眼手术疗效的影响：12个月随访结果

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2025-01-17 DOI: 10.1177/11206721251313835

Ali Olgun, Murat Karapapak

{"title":"Impact of mitomycin C on surgical outcomes of PAUL glaucoma implant in neovascular glaucoma: 12-month follow-up results.","authors":"Ali Olgun, Murat Karapapak","doi":"10.1177/11206721251313835","DOIUrl":"10.1177/11206721251313835","url":null,"abstract":"PurposeTo evaluate the effectiveness of the PAUL Glaucoma Implant (PGI) and the adjunctive impact of intraoperative Mitomycin C (MMC) on surgical outcomes in patients with neovascular glaucoma (NVG).MethodsThis retrospective, comparative study included NVG patients who underwent PGI implantation. The cohort was divided into two groups: Group 1 (PGI without MMC) and Group 2 (PGI with MMC). Inclusion criteria encompassed a minimum 12-month postoperative follow-up and preoperative light perception. Surgical success was defined as maintaining intraocular pressure (IOP) between 6-21 mmHg without additional surgical intervention from the third month to the end of the 12-month follow-up. Failure due to hypotony was defined as an IOP ≤5 mmHg.ResultsThe study enrolled a total of eighty-one patients, with 40 patients in Group 1 and 41 in Group 2. There were no significant differences in the demographic data and baseline ocular characteristics between the groups. Group 1 required more medications at 1, 3, 6, and 12 months (p < 0.05 for all). Surgical success rates at 12 months were 85% for Group 1 and 87.8% for Group 2, with no statistically significant difference between the groups (p = 0.140). Group 2 demonstrated a lower frequency of additional glaucoma procedures (p = 0.003) and delayed ripcord suture removal (p = 0.0001).ConclusionsIncorporating MMC as an adjunct to PGI implantation may improve IOP control and decrease the requirement for additional medications and surgical interventions in NVG patients. However, there was no statistically significant difference between the two groups in terms of the surgical success criterion.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1305-1313"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0