European Journal of Ophthalmology最新文献

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Comparison of 3-month clinical outcomes between two enhanced monofocal intraocular lenses: A single-center prospective study. 两种增强型单焦点眼内透镜 3 个月临床疗效的比较:单中心前瞻性研究。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2024-11-15 DOI: 10.1177/11206721241298031
Vito Spagnuolo, Giulio Vicini, Ginevra Marincolo, Alessandro Franchini, Fabrizio Giansanti, Cinzia Mazzini
{"title":"Comparison of 3-month clinical outcomes between two enhanced monofocal intraocular lenses: A single-center prospective study.","authors":"Vito Spagnuolo, Giulio Vicini, Ginevra Marincolo, Alessandro Franchini, Fabrizio Giansanti, Cinzia Mazzini","doi":"10.1177/11206721241298031","DOIUrl":"10.1177/11206721241298031","url":null,"abstract":"<p><p>PurposeThis study aims to compare the 3-month clinical outcomes between two enhanced monofocal intraocular lenses (IOLs) following cataract surgery.Setting: Eye Clinic of Careggi University Hospital, Florence, Italy.DesignSingle-center prospective study.MethodsWe included patients with cataract and corneal astigmatism less than 0.75 D, with no ocular comorbidities, who underwent unilateral cataract surgery with implantation of either the Tecnis Eyhance ICB00 (<i>N</i> = 25) or Evolux (<i>N</i> = 25) IOLs. Standard cataract procedures were performed without complications. The main outcome measures included uncorrected and corrected visual acuity at distance (4 m), intermediate (60 cm) and near (40 cm) at 3-month follow-up. Additionally, monocular defocus curves, aberrometric profiles, and perceptions of halo and glare were evaluated.ResultsThe study involved 50 patients (26 male, 24 female) with a mean age of 68 ± 8 years. Preoperative characteristics were similar between the groups, and no intraoperative or postoperative complications were reported. Statistically significant differences were observed between the groups, with the Evolux IOL showing superior results (<i>p</i> < 0.05) in terms of uncorrected and corrected visual acuity at near, intermediate, and distance, as well as in aberrometric profiles (lower-order aberration root-mean-square [RMS], higher-order aberration RMS, spherical equivalent RMS, and point spread function) and defocus curves.ConclusionsBased on our experience, while both IOLs offer substantial visual performance for intermediate and distance vision, the Evolux IOL demonstrated superior mean visual outcomes and objective parameters at the 3-month follow-up compared to the Tecnis Eyhance IOL. This indicates a potential advantage of the Evolux IOL in providing better visual performance.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"922-929"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142617367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in choroidal thickness and lamina cribrosa position in subjects with overdipper pattern of arterial pressure. 动脉压过低模式受试者脉络膜厚度和脉络膜嵴位置的变化。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2024-11-15 DOI: 10.1177/11206721241298126
A Cerveró, B Gutiérrez, C Cerveró, S Crespo, A Casado, J Riancho
{"title":"Changes in choroidal thickness and lamina cribrosa position in subjects with overdipper pattern of arterial pressure.","authors":"A Cerveró, B Gutiérrez, C Cerveró, S Crespo, A Casado, J Riancho","doi":"10.1177/11206721241298126","DOIUrl":"10.1177/11206721241298126","url":null,"abstract":"<p><p>IntroductionThe purpose is to analyze the changes produced in subjects with an overdipper pattern of ambulatory blood pressure monitoring with the aim of understanding the pathophysiology of normal tension glaucoma.MethodsA cross sectional study was performed in patients exhibiting overdipper and non-overdipper blood pressure patterns, respectively. Different optic parameters were assessed including the analysis of ganglion cell layer (GCL), peripapillary retinal nerve fiber layer (pRNFL) and Bruch's membrane opening-minimum rim width (BMO-MRW), as well as changes produced in choroidal thickness (CT) and lamina cribrosa (LC) position at two different periods of the day (early morning and evening).ResultsA total of 80 eyes (42 overdipper and 38 non-overdipper) were analyzed. A shortening of the distance at the beginning and end of the LC was objectified in the overdipper subjects (<i>p</i> < 0.003) as well as a statistically significant shift of the LC between morning and evening measurements in the overdipper subjects (<i>p</i> < 0.023). In addition, a significant thickening was found in 13 measurements of the horizontal and vertical plane CT (<i>p</i> < 0.029) of the overdipper subjects and a thickening of the CT in both groups in the morning. No significant differences in pRNFL, BMO-MRW and GCL measures were objectified.ConclusionsMorning assessment in overdipper subjects showed a deeper LC and a LC shift in comparison to evening values. In addition, an increase in CT was found in these subjects. Altogether, these findings could illustrate an etiopathogenic mechanism of the damage produced in normal tension glaucoma associated to the overdipper pattern.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"947-960"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142617362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corneal endothelial neovascularization and glaucoma in X-linked Alport syndrome. 角膜内皮新生血管与x连锁Alport综合征青光眼的关系。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2025-02-13 DOI: 10.1177/11206721251313663
Lin Zhou, Yao Zhang, Chaohua Tian, Jinying Liao, Houjue Yu, Li Tang
{"title":"Corneal endothelial neovascularization and glaucoma in X-linked Alport syndrome.","authors":"Lin Zhou, Yao Zhang, Chaohua Tian, Jinying Liao, Houjue Yu, Li Tang","doi":"10.1177/11206721251313663","DOIUrl":"10.1177/11206721251313663","url":null,"abstract":"<p><p>IntroductionVariants in <i>COL4A5</i> are responsible for X-linked Alport syndrome. It is characterized by kidney disease, sensorineural hearing loss and variable ocular abnormalities. In this case, a woman with corneal endothelial neovascularization, glaucoma, nuclear cataract, temporal retinal thinning, and renal defects was identified with a variant in <i>COL4A5</i>.Case presentationWe described a 64-year-old woman who was referred to our Eye Clinic due to a progressive decline in vision in both eyes over the course of two years. Corneal endothelial neovascularization, elevated intraocular pressure (31.2 mmHg and 27.8 mmHg in the right and left eyes, respectively), lens opacity, an increased cup-to-disc (C/D) ratio (0.8 in both eyes), and thinner retinal nerve fiber layer were detected upon examination. Concurrently, microscopic hematuria and proteinuria were observed. Following phacoemulsification and the administration of Latanoprost, intraocular pressure returned to within the normal range. Whole exome sequencing revealed a novel hemizygous missense pathogenic variant in COL4A5 (c.3980G > T (p.G1327V)). Importantly, this particular variant was not identified in the healthy daughter of the proband, underscoring its potential relevance to the observed clinical manifestations.ConclusionsOur study reports a novel phenotype observed in a 64-year-old woman, featuring corneal endothelial neovascularization and glaucoma, which has been linked to X-linked Alport syndrome caused by variants in <i>COL4A5</i>. This discovery contributes to the broadening of our understanding of the clinical heterogeneity associated with <i>COL4A5</i> variants.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"NP1-NP6"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between controlling nutritional status score and diabetic retinopathy: Data from National Health and Nutrition Examination Survey. 控制营养状况评分与糖尿病视网膜病变的关系:来自全国健康与营养检查调查的数据。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2024-10-17 DOI: 10.1177/11206721241289971
Yimeng Ruan, Ping Zhang, Xinru Jia, Shanshan Hua, Dongwei Yao
{"title":"Association between controlling nutritional status score and diabetic retinopathy: Data from National Health and Nutrition Examination Survey.","authors":"Yimeng Ruan, Ping Zhang, Xinru Jia, Shanshan Hua, Dongwei Yao","doi":"10.1177/11206721241289971","DOIUrl":"10.1177/11206721241289971","url":null,"abstract":"<p><p>ObjectiveThis study aimed to examine the association between controlling nutritional status (CONUT) score and diabetic retinopathy (DR) risk, as well as investigate the impact of CONUT score on mortality risk among DR patients.MethodsThis retrospective study included 5,256 patients with diabetes from National Health and Nutrition Examination Surveys. These participants were classified into two groups: the DR group (<i>n</i> = 641) and the non-DR group (<i>n</i> = 4,615). We used weighted univariate and multivariate logistic regression models to assess the correlation of CONUT score and DR risk. Weighted univariate and multivariate Cox models were adopted to explore the association of CONUT score with all-cause mortality and cardiovascular disease (CVD)-related mortality in patients with DR.Results305 patients diagnosed with DR had died by the end of the follow-up period, among whom 111 individuals died due to CVD. After adjusting all potential confounding factors, there was an association between CONUT score and DR development in patients with diabetes [odd ratio (OR) = 1.18, 95% confidence interval (CI): 1.05-1.33]. Additionally, CONUT score was found to be associated with all-cause mortality of patients with DR [hazard ratio (HR) = 1.11, 95%CI: 1.01-1.22, <i>P</i>= 0.041]. However, there was no significant difference in the CONUT score and CVD-related mortality of patients with DR.ConclusionsCONUT score may be a valuable tool for assessing the risk of developing DR, and predicting prognosis in patients with DR. However, as this was a cross-sectional study, we cannot infer the causality of CONUT score and DR risk.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1082-1090"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization and topographical analysis of choroidal caverns in young and healthy individuals. 年轻健康人脉络膜洞穴的特征和地形分析。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2024-10-15 DOI: 10.1177/11206721241289970
Serena Fragiotta, Lisa Toto, Mariacristina Parravano, Alberto Quarta, Michele Di Noia, Riccardo Sacconi, Darja Dobovsek Divjak, Federico Rissotto, Maria Sole Polito, Eliana Costanzo, Giuseppe Querques
{"title":"Characterization and topographical analysis of choroidal caverns in young and healthy individuals.","authors":"Serena Fragiotta, Lisa Toto, Mariacristina Parravano, Alberto Quarta, Michele Di Noia, Riccardo Sacconi, Darja Dobovsek Divjak, Federico Rissotto, Maria Sole Polito, Eliana Costanzo, Giuseppe Querques","doi":"10.1177/11206721241289970","DOIUrl":"10.1177/11206721241289970","url":null,"abstract":"<p><p>PurposeTo describe and clarify a possible pathogenetic origin for choroidal caverns in young healthy individuals through a topographical analysis using swept-source optical coherence tomography angiography (SS-OCTA).MethodsA cross-sectional evaluation of 44 healthy volunteers (44 eyes), aged 20-32 years with no systemic or ocular comorbidities. The topographical analysis of choroidal caverns was performed through a 15 × 15 mm volumetric scan cube using SS-OCTA (PLEX Elite 9000). The number, topographic localization within the perifovea and midperipheral retina, as well as the density of choroidal caverns in the area with the highest number, were analyzed. Factors influencing the presence of choroidal caverns were identified using a logistic regression model.ResultsThe overall prevalence of choroidal caverns was 18.2% in our cohort. The subjects exhibiting choroidal caverns presented a greater AXL (+1.19 mm, 95%CI: 0.09, 2.29). Areas with the highest density of caverns presented an average of 1.98 ± 1.01 caverns/mm<sup>2</sup>. On a qualitative evaluation, the area with the highest density was along the inferior vascular arcade in 6/8 (75%) eyes. The main predictor of choroidal cavern development was represented by AXL (adjusted risk ratio of 2.13, <i>P</i> = 0.02).ConclusionChoroidal caverns in young, healthy individuals may form due to mechanical stress in predisposed eyes, where an increased lateral and anteroposterior choroidal stretching due to globe elongation can result in the formation of these cavities. Future longitudinal studies are encouraged to understand their prognostic implications.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1029-1035"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of ranibizumab and aflibercept on reducing maximum diameter of largest cyst in diabetic cystoid macular edema: MARMASIA study group. 雷尼珠单抗和阿夫利拜因对缩小糖尿病囊样黄斑水肿最大囊肿直径的疗效:MARMASIA研究小组。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2024-09-05 DOI: 10.1177/11206721241280737
Ecem Önder Tokuç, V Levent Karabaş, Mehmet Orkun Sevik, Fatih Bilgehan Kaplan, Işıl Kutlutürk Karagöz, Hatice Selen Kanar, Uğur Yayla, Ayşe Demirciler Sönmez, Aslan Aykut, Utku Limon, Erdinç Bozkurt, Işılay Özsoy Saygın, Tuğba Aydoğan Gezginaslan, Nimet Yeşim Erçalık, Esra Kumral Türkseven, Özlem Aydın Öncü, Erkan Çelik, Ece Başaran Emengen, Abdullah Özkaya, Banu Açıkalın Öncel, Nursal Melda Yenerel, Özlem Şahin
{"title":"Efficacy of ranibizumab and aflibercept on reducing maximum diameter of largest cyst in diabetic cystoid macular edema: MARMASIA study group.","authors":"Ecem Önder Tokuç, V Levent Karabaş, Mehmet Orkun Sevik, Fatih Bilgehan Kaplan, Işıl Kutlutürk Karagöz, Hatice Selen Kanar, Uğur Yayla, Ayşe Demirciler Sönmez, Aslan Aykut, Utku Limon, Erdinç Bozkurt, Işılay Özsoy Saygın, Tuğba Aydoğan Gezginaslan, Nimet Yeşim Erçalık, Esra Kumral Türkseven, Özlem Aydın Öncü, Erkan Çelik, Ece Başaran Emengen, Abdullah Özkaya, Banu Açıkalın Öncel, Nursal Melda Yenerel, Özlem Şahin","doi":"10.1177/11206721241280737","DOIUrl":"10.1177/11206721241280737","url":null,"abstract":"<p><p>PurposeThis study aimed to compare the effect of intravitreal aflibercept (IVA) and ranibizumab (IVR) on the maximal diameter of the largest intraretinal cyst (mdIRC), indicating chronicity in patients with diabetic cystoid macular edema (CME).MethodsThis retrospective, comparative study included a subgroup of patients from the MARMASIA Study with treatment-naïve diabetic CME who had IVA (IVA group) or IVR (IVR group) on a pro re nata regimen after a loading dose of 3-monthly injections and followed-up for 24 months. Best-corrected visual acuity (logMAR), central macular thickness (CMT, µm), and mdIRC (µm) and their changes during the study period in the IVA and IVR groups were compared.ResultsA total of 175 eyes (65 [37.1%] in IVA and 110 [62.9%] in IVR group) of 113 patients were included in the study analysis. Both groups had statistically significant improvements in BCVA and CMT during the follow-up (p < 0.05 for all), which were comparable between the groups at each time point. However, the mean reduction in mdIRCs was consistently and significantly higher in the IVA group compared to the IVR group at each follow-up examination (F[1, 3.52] = 6.93, p = 0.009).ConclusionIVA seems to have a greater impact in reducing cyst sizes than IVR in diabetic CME.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"980-989"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the visual function with the continuous transitional focus intraocular lens Precizon Presbyopic. 使用连续过渡聚焦眼内透镜 Precizon Presbyopic 分析视觉功能。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2024-11-03 DOI: 10.1177/11206721241293830
Luis León-Ibáñez, David P Piñero
{"title":"Analysis of the visual function with the continuous transitional focus intraocular lens Precizon Presbyopic.","authors":"Luis León-Ibáñez, David P Piñero","doi":"10.1177/11206721241293830","DOIUrl":"10.1177/11206721241293830","url":null,"abstract":"<p><p>PurposeTo evaluate the clinical outcomes of a refractive multi-segmented continuous transitional focus intraocular lens (IOL), analyzing the potential influence of patient pupil dynamics on these outcomes.MethodsRetrospective consecutive case series study enrolling 40 eyes (20 patients, 47-81 years) implanted with the Precizon Presbyopic IOL (Ophtec BV). The following clinical outcomes were analyzed during a mean follow-up of 12.1 months (2-24 months): visual acuity, refraction, contrast sensitivity (CS) under photopic and mesopic conditions, binocular defocus curve and evaluation of the perception of disturbing visual symptoms with a validated questionnaire.ResultsMean binocular uncorrected distance (UDVA), distance-corrected intermediate (DCIVA), uncorrected near (UNVA) and distance-corrected near visual acuities (DCNVA) were -0.09 ± 0.07, 0.04 ± 0.05, 0.17 ± 0.12, and 0.15 ± 0.10 logMAR, respectively. In the binocular defocus curve, mean distance-corrected visual acuity was over 0.20 logMAR for defocus levels from +1.50 to -3.00 D. No significant correlations of photopic pupil diameter with postoperative visual data were found (-0.165 ≤ r ≤ 0.192, p ≥ 0.235). Moderate correlations of mesopic pupil size were found with visual acuities for the defocus levels of -2.50 (<i>r</i> = 0.454, <i>p</i> = 0.003), -3.00 (<i>r</i> = 0.609, <i>p</i> < 0.001), -3.50 (<i>r</i> = 0.519, <i>p</i> < 0.001), and -4.00 D (<i>r</i> = 0.403, <i>p</i> = 0.010). Only significant differences were found between mesopic and photopic CS for 12 cycles/degree (<i>p</i> = 0.010). No cases of severe glare or halos were detected. In contrast, 10% of patients referred the severe perception of starbursts postoperatively. Full spectacle independence was referred by almost all patients (90%).ConclusionsThe IOL demonstrates effective visual restoration at various distances, characterized by high levels of visual quality and minimal dependence on pupil dynamics.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"930-937"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Removable regulating sutures during trabeculectomy for a safer and more effective intraocular pressure control. 在小梁切除术中使用可拆卸的调节缝合线,可更安全、更有效地控制眼压。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2024-08-14 DOI: 10.1177/11206721241276573
Alfonso Savastano, Emanuele Maiola, Matteo Mario Carlà, Gloria Gambini, Francesco Boselli, Federico Giannuzzi, Clara Rizzo, Stanislao Rizzo
{"title":"Removable regulating sutures during trabeculectomy for a safer and more effective intraocular pressure control.","authors":"Alfonso Savastano, Emanuele Maiola, Matteo Mario Carlà, Gloria Gambini, Francesco Boselli, Federico Giannuzzi, Clara Rizzo, Stanislao Rizzo","doi":"10.1177/11206721241276573","DOIUrl":"10.1177/11206721241276573","url":null,"abstract":"<p><p>PurposeComparing the effect of standard trabeculectomy with direct sutures versus trabeculectomy with compression and everting sutures.MethodsMono-centric randomized prospective comparative study on 38 glaucomatous eyes undergoing trabeculectomy: 19 with standard fixed sutures (group A) and 19 withremovable regulating sutures (group B). Preoperatively and at day-7, 1-month, 2-months, 3-months and 6-months after surgery, we recorded best-corrected visual acuity (BCVA), intraocular pressure (IOP) and possible complications. Complete, partial success and failure rates were recorded at the end of the study.ResultsIn group B, we pulled everting sutures with the \"horse bridle\" technique at the 14<sup>th</sup> day, and successively removed all sutures between the 14<sup>th</sup>-30<sup>th</sup> post-operative day. At month-1, we recorded a significant IOP reduction in both groups (mean reduction of 11.5 mmHg for group A and of 14.4 mmHg for Group B, p = 0.001 and p < 0.0001, respectively). Furthermore, group B showed a significantly lower IOP than group A (-4.2 mmHg, 95% confidence interval [CI] -7.0 to -0.5 mmHg for group B, p = 0.01). At 2, 3 and 6-months, no significant IOP differences were reported between the two groups (all p > 0.05), but failure rate was higher for group A (21%) than for group B (11%). No differences in visual outcomes at any timepoints were noted.ConclusionsTrabeculectomy with removable regulating sutures showed a good safety profile, comparable to standard trabeculectomy. Moreover, we reported a lower IOP one month postoperatively, suggesting this technique may optimize early management of trabeculectomy.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"961-971"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric refractive surgery: Review article. 小儿屈光手术:评论文章。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2024-10-13 DOI: 10.1177/11206721241290261
Maan Alkharashi, Moath Alowairdhi, Norah Albdaya, Rakan Alzabadin
{"title":"Pediatric refractive surgery: Review article.","authors":"Maan Alkharashi, Moath Alowairdhi, Norah Albdaya, Rakan Alzabadin","doi":"10.1177/11206721241290261","DOIUrl":"10.1177/11206721241290261","url":null,"abstract":"<p><p>Refractive surgery is one of the most commonly performed elective procedures in ophthalmology; it is mostly performed in patients who are older than 18 years of age. This routine procedure has been time-tested and is proven to be both safe and effective in adults. However, little is known about the safety and efficacy of refractive surgery in pediatric patients. Granted, refractive surgery should not be used in kids merely for the purpose of avoiding spectacles wear, but it can be of valuable help is preserving vision in patients with amblyopia and accommodative esotropia who otherwise couldn't comply with traditional management options. Refractive surgery in pediatric patients is a complex and challenging field due to the unique characteristics of their developing eyes. This review article aims to provide an overview of the current literature on refractive surgery in pediatric patients, focusing on the different surgical options, the advantages and disadvantages of each procedure.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"799-808"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geographic atrophy progression secondary to age-related macular degeneration: Five years of follow-up. 继发于老年性黄斑变性的地理萎缩进展:五年随访
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2024-10-24 DOI: 10.1177/11206721241287252
Elham Sadeghi, Nicola Valsecchi, Sharat Chandra Vupparaboina, Kunaal Mehrotra, Kiran Kumar Vupparaboina, Sandeep Chandra Bollepalli, Jose-Alain Sahel, Andrew W Eller, Jay Chhablani
{"title":"Geographic atrophy progression secondary to age-related macular degeneration: Five years of follow-up.","authors":"Elham Sadeghi, Nicola Valsecchi, Sharat Chandra Vupparaboina, Kunaal Mehrotra, Kiran Kumar Vupparaboina, Sandeep Chandra Bollepalli, Jose-Alain Sahel, Andrew W Eller, Jay Chhablani","doi":"10.1177/11206721241287252","DOIUrl":"10.1177/11206721241287252","url":null,"abstract":"<p><p>PurposeTo study the progression of geographic atrophy (GA) secondary to age-related macular degeneration over a five-year follow-up.MethodsEyes with GA included to assess demographic data, yearly optical coherence tomography (OCT) findings and the GA growth rate on infra-red (IR) images.ResultsA total of 41 eyes of 29 patients were included with a mean age of 81.76 ± 6.37 at baseline, and 65.51% were females. Over five years, there was a significant increase in the mean GA area from 8.44 ± 8.98 mm² to 13.32 ± 10.07 mm² (P < 0.001), with an annual growth rate of 1.14 ± 0.78 mm². The annual growth rates in females were slightly higher compared to males (1.29 ± 0.89 mm2 vs 0.96 ± 0.49 mm2, p = 0.569), and in smokers was slightly higher than non-smokers (1.35 ± 0.85 mm2 vs 0.94 ± 0.66 mm2, p = 0.100). Larger GA areas at the baseline showed higher GA progression in mm<sup>2</sup> per year (P = 0.04). Smaller GA areas and fovea-spared GA at the baseline exhibited a larger percentage increase (P < 0.001 and P = 0.015, respectively). There was a lower GA progression rate in eyes with outer retinal tubulations (ORT) (P = 0.027), yet no significant correlation was found between GA progression and other OCT features.ConclusionsSmaller, fovea-sparing GA eyes experienced a more substantial proportional increase over five years. Also, The presence of ORT was associated with a slower rate of GA progression. Additionally, we observed a trend of faster GA growth in smokers and female genders.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"996-1004"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142497541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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