European Journal of Ophthalmology最新文献

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The performance of ChatGPT-4 and Bing Chat in frequently asked questions about glaucoma.
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-02-19 DOI: 10.1177/11206721251321197
Levent Doğan, İbrahim Edhem Yılmaz
{"title":"The performance of ChatGPT-4 and Bing Chat in frequently asked questions about glaucoma.","authors":"Levent Doğan, İbrahim Edhem Yılmaz","doi":"10.1177/11206721251321197","DOIUrl":"https://doi.org/10.1177/11206721251321197","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the appropriateness and readability of the responses generated by ChatGPT-4 and Bing Chat to frequently asked questions about glaucoma.</p><p><strong>Method: </strong>Thirty-four questions were generated for this study. Each question was directed three times to a fresh ChatGPT-4 and Bing Chat interface. The obtained responses were categorised by two glaucoma specialists in terms of their appropriateness. Accuracy of the responses was evaluated using the Structure of the Observed Learning Outcome (SOLO) taxonomy. Readability of the responses was assessed using Flesch Reading Ease (FRE), Flesch Kincaid Grade Level (FKGL), Coleman-Liau Index (CLI), Simple Measure of Gobbledygook (SMOG), and Gunning- Fog Index (GFI).</p><p><strong>Results: </strong>The percentage of appropriate responses was 88.2% (30/34) and 79.2% (27/34) in ChatGPT-4 and Bing Chat, respectively. Both the ChatGPT-4 and Bing Chat interfaces provided at least one inappropriate response to 1 of the 34 questions. The SOLO test results for ChatGPT-3.5 and Bing Chat were 3.86 ± 0.41 and 3.70 ± 0.52, respectively. No statistically significant difference in performance was observed between both LLMs (<i>p</i> = 0.101). The mean count of words used when generating responses was 316.5 (± 85.1) and 61.6 (± 25.8) in ChatGPT-4 and Bing Chat, respectively (<i>p</i> < 0.05). According to FRE scores, the generated responses were suitable for only 4.5% and 33% of U.S. adults in ChatGPT-4 and Bing Chat, respectively (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>ChatGPT-4 and Bing Chat consistently provided appropriate responses to the questions. Both LLMs had low readability scores, but ChatGPT-4 provided more difficult responses in terms of readability.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251321197"},"PeriodicalIF":1.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frosted branch angiitis post COVID vaccine: A presumptive association with Behçet's disease.
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-02-19 DOI: 10.1177/11206721251321537
Victor Alegre-Ituarte, Bahram Bodaghi, Sara Touhami
{"title":"Frosted branch angiitis post COVID vaccine: A presumptive association with Behçet's disease.","authors":"Victor Alegre-Ituarte, Bahram Bodaghi, Sara Touhami","doi":"10.1177/11206721251321537","DOIUrl":"https://doi.org/10.1177/11206721251321537","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case highlighting the uncommon presentation of Frosted Branch Angiitis (FBA) in Behçet's Disease (BD), notably in a patient who received a COVID vaccine one month prior to the onset of symptoms. We explore the possible role of vaccination in unmasking BD.</p><p><strong>Methods: </strong>A comprehensive evaluation of a 45-year-old patient with FBA post-COVID vaccination was undertaken.</p><p><strong>Results: </strong>The patient exhibited characteristic features of FBA, with classic perivascular sheathing, optic disc edema, and retinal ischemia, which manifested one month after receiving the Pfizer/BioNTech COVID vaccine. Despite a history of recurrent oral aphthosis, systemic workup for autoimmune conditions was unremarkable. Diagnosis of presumptive Behçet's Disease was made based on clinical criteria. Treatment with intravenous methylprednisolone and infliximabn (5 mg/kg) led to complete resolution of ocular symptoms and retinal signs.</p><p><strong>Conclusion: </strong>FBA is an uncommon presentation of BD. This case also serves as a stark reminder of the potential consequences of vaccination on immune-mediated diseases. However, the correlation between FBA onset, COVID vaccination, and Behçet's Disease diagnosis necessitates cautious interpretation. Successful use of methylprednisolone and infliximab in achieving resolution of visual symptoms highlights potential therapeutic considerations in similar cases.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251321537"},"PeriodicalIF":1.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ophthalmic findings leading to diagnose chronic myeloid leukemia: A multimodal image case report.
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-02-18 DOI: 10.1177/11206721251321534
Andrea Hoyos, Juan Carlos Lugo, Valentina Pérez-Vergara
{"title":"Ophthalmic findings leading to diagnose chronic myeloid leukemia: A multimodal image case report.","authors":"Andrea Hoyos, Juan Carlos Lugo, Valentina Pérez-Vergara","doi":"10.1177/11206721251321534","DOIUrl":"https://doi.org/10.1177/11206721251321534","url":null,"abstract":"<p><strong>Purpose: </strong>Chronic myeloid leukemia (CML) is a rare malignant myeloproliferative disorder characterized by the presence of the Philadelphia chromosome, a reciprocal translocation between chromosomes 9 and 22. Ocular manifestations in CML are infrequent but can be the initial indicators of the disease. We report the case of a 28-year-old male patient with suspected hyperviscosity syndrome secondary to CML, based on fundus findings and supported by multimodal imaging.</p><p><strong>Methods: </strong>Multimodal imaging was performed to assess the ocular manifestations, before and after treatment.</p><p><strong>Results: </strong>The patient presented with posterior segment findings consistent with hyperviscosity syndrome, including retinal hemorrhages, vascular dilation, and tortuosity as demonstrated by multimodal imaging techniques. Further investigations confirmed the diagnosis of CML, and treatment with hydroxyurea, allopurinol, and imatinib led to a significant improvement in visual acuity and resolution of posterior segment findings.</p><p><strong>Conclusion: </strong>Ocular manifestations in CML vary widely and include both anterior and posterior segment involvement. Regular ophthalmic examinations are essential for the early detection of relapses or complications. This case underscores the importance of interdisciplinary collaboration between ophthalmologists and hematologists for the timely diagnosis and management of ocular manifestations in CML.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251321534"},"PeriodicalIF":1.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Face-up vs face-down positioning after rhegmatogenous macula-off retinal detachment surgery: Hypothesis of better recovery.
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-02-16 DOI: 10.1177/11206721251318764
Alfonso Savastano, Valerio Calabresi, Emanuele Crincoli, Maria Cristina Savastano, Umberto De Vico Umberto, Nicola Claudio D'Onofrio, Stanislao Rizzo, Andrea Govetto
{"title":"Face-up vs face-down positioning after rhegmatogenous macula-off retinal detachment surgery: Hypothesis of better recovery.","authors":"Alfonso Savastano, Valerio Calabresi, Emanuele Crincoli, Maria Cristina Savastano, Umberto De Vico Umberto, Nicola Claudio D'Onofrio, Stanislao Rizzo, Andrea Govetto","doi":"10.1177/11206721251318764","DOIUrl":"https://doi.org/10.1177/11206721251318764","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the differences between two distinct patient postoperative positions following rhegmatogenous macula-off retinal detachment surgery.</p><p><strong>Methods: </strong>In this consecutive clinical study, 26 patients were placed in either the face-up or face-down postoperative position group. Postoperative follow-ups were conducted at 1, 3, and 6 months using type 1 M-CHARTS, best-corrected visual acuity (BCVA), intraocular pressure, and optical coherence tomography imaging to evaluate the functional and anatomical outcomes after surgery.</p><p><strong>Results: </strong>The average vision recovery at 6 months was 0.35159 +/- 0.30945 logarithm of the minimum angle of resolution (logMAR) for the face-up group and 0.81521+/- 0.46662 logMAR for the face-down group. At 6 months, the average horizontal type 1 M-CHARTS for the face-up group was 0.1615 +/- 0.1710 and 0.2846 +/- 0.2828 for the face-down group; and the average vertical type 1 M-CHARTS was 0.1615 +/- 0.1557 for the face-up group and 0.2846 +/- 0.1725 for the face-down group.</p><p><strong>Conclusion: </strong>The face-up position demonstrated significant improvement in both metamorphopsia and BCVA, suggesting that slow reattachment of photoreceptors on the retinal pigment epithelium layer can result in better quality of sight recovery.Further studies with larger sample sizes are warranted to confirm these results.The study adhered to the guidelines of the Declaration of Helsinki.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251318764"},"PeriodicalIF":1.4,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corneal endothelial neovascularization and glaucoma in X-linked Alport syndrome.
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-02-13 DOI: 10.1177/11206721251313663
Lin Zhou, Yao Zhang, Chaohua Tian, Jinying Liao, Houjue Yu, Li Tang
{"title":"Corneal endothelial neovascularization and glaucoma in X-linked Alport syndrome.","authors":"Lin Zhou, Yao Zhang, Chaohua Tian, Jinying Liao, Houjue Yu, Li Tang","doi":"10.1177/11206721251313663","DOIUrl":"https://doi.org/10.1177/11206721251313663","url":null,"abstract":"<p><strong>Introduction: </strong>Variants in <i>COL4A5</i> are responsible for X-linked Alport syndrome. It is characterized by kidney disease, sensorineural hearing loss and variable ocular abnormalities. In this case, a woman with corneal endothelial neovascularization, glaucoma, nuclear cataract, temporal retinal thinning, and renal defects was identified with a variant in <i>COL4A5</i>.</p><p><strong>Case presentation: </strong>We described a 64-year-old woman who was referred to our Eye Clinic due to a progressive decline in vision in both eyes over the course of two years. Corneal endothelial neovascularization, elevated intraocular pressure (31.2 mmHg and 27.8 mmHg in the right and left eyes, respectively), lens opacity, an increased cup-to-disc (C/D) ratio (0.8 in both eyes), and thinner retinal nerve fiber layer were detected upon examination. Concurrently, microscopic hematuria and proteinuria were observed. Following phacoemulsification and the administration of Latanoprost, intraocular pressure returned to within the normal range. Whole exome sequencing revealed a novel hemizygous missense pathogenic variant in COL4A5 (c.3980G > T (p.G1327V)). Importantly, this particular variant was not identified in the healthy daughter of the proband, underscoring its potential relevance to the observed clinical manifestations.</p><p><strong>Conclusions: </strong>Our study reports a novel phenotype observed in a 64-year-old woman, featuring corneal endothelial neovascularization and glaucoma, which has been linked to X-linked Alport syndrome caused by variants in <i>COL4A5</i>. This discovery contributes to the broadening of our understanding of the clinical heterogeneity associated with <i>COL4A5</i> variants.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251313663"},"PeriodicalIF":1.4,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nepafenac role in macular swelling prevention and in visual outcome after cataract surgery - a systematic review and meta-analysis.
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-02-12 DOI: 10.1177/11206721251317652
Malaz Almasri, Amjad Ghareeb, Abdulrahman Ismaiel, Daniel-Corneliu Leucuta, Simona Delia Nicoara
{"title":"Nepafenac role in macular swelling prevention and in visual outcome after cataract surgery - a systematic review and meta-analysis.","authors":"Malaz Almasri, Amjad Ghareeb, Abdulrahman Ismaiel, Daniel-Corneliu Leucuta, Simona Delia Nicoara","doi":"10.1177/11206721251317652","DOIUrl":"https://doi.org/10.1177/11206721251317652","url":null,"abstract":"<p><strong>Purpose: </strong>To compare Nepafenac effect on foveal thickness (FT), total macular volume (TMV), and BCVA after cataract surgery when added to the common regimen of topical steroids perioperatively.</p><p><strong>Methods: </strong>PubMed, Scopus, EMBASE, the Cochrane Library, and ClinicalTrials.gov were searched systematically on April 28, 2022, for RCTs. Our primary outcome was the change in FT at final follow-up visits. We also considered FT at different follow-up durations, TMV, and visual outcome. We summarized our analyses by calculating the mean differences (MD) with associated 95% confidence intervals (CI) using restricted maximum likelihood in random effects models for continuous outcomes. The individual trials were evaluated for quality utilizing the Cochrane Collaboration's risk of bias assessment tool.</p><p><strong>Results: </strong>Twenty-four RCTs totaling 4716 eyes were eligible. A significant difference was found between Nepafenac group and control group in the change in FT at final follow-up visit (MD, -11.622; 95% Cl [-17.475, -5.769]), at one week follow-up visit (MD, -6.409; 95% Cl [-13.148, 0.330]), at one month follow-up visit (MD, -9.090; 95% Cl [-13.260, -4.919]), at two months (MD, -5.769; 95% Cl (-22.477, -10.939]), and at three-month follow-up visit (MD, -12.913; 95% Cl [-22.254, -3.572]). However, there was no significant difference between the two groups regarding change in TMV at final follow-up visit. Nevertheless, a significant difference was found between the two groups regarding post-operative BCVA only at three-month follow-up visit.</p><p><strong>Conclusion: </strong>Topical Nepafenac in addition to topical steroid is superior to the common regimen of topical steroid alone perioperatively in the prevention of macular swelling.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251317652"},"PeriodicalIF":1.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Torpedo maculopathy in a patient with DeSanto-Shinawi syndrome.
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-02-12 DOI: 10.1177/11206721251313840
Sergio Petroni, Gino Catena, Giancarlo Iarossi, Matteo Federici, Gaetano Zinzanella, Carlo Maria De Sanctis, Paola Valente, Luca Buzzonetti
{"title":"Torpedo maculopathy in a patient with DeSanto-Shinawi syndrome.","authors":"Sergio Petroni, Gino Catena, Giancarlo Iarossi, Matteo Federici, Gaetano Zinzanella, Carlo Maria De Sanctis, Paola Valente, Luca Buzzonetti","doi":"10.1177/11206721251313840","DOIUrl":"https://doi.org/10.1177/11206721251313840","url":null,"abstract":"<p><strong>Introduction: </strong>Torpedo maculopathy (TM) is a rare, typically benign and congenital anomaly of the retinal pigment epithelium (RPE) characterized by a torpedo-shaped lesion in the macula. DeSanto-Shinawi syndrome (DESS) is an equally rare genetic disorder caused by mutations in the WAC gene, presenting with intellectual disability, dysmorphic features, and growth retardation.</p><p><strong>Case description: </strong>This report illustrates the case of monolateral TM in a patient with DESS. The genetic and phenotypic characteristic were described and correlated with retinal features, assessed by means of retinography, spectral domain OCT (SD-OCT) and fluorescein angiography (FA).</p><p><strong>Conclusion: </strong>This case report discusses the unusual co-occurrence of TM in a patient diagnosed with DESS, contributing to the sparse literature on this association and expanding the phenotypic spectrum of both conditions.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251313840"},"PeriodicalIF":1.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report.
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-02-12 DOI: 10.1177/11206721241310629
Clara Rizzo, Maria Cristina Savastano, Raphael Kilian, Stanislao Rizzo
{"title":"Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report.","authors":"Clara Rizzo, Maria Cristina Savastano, Raphael Kilian, Stanislao Rizzo","doi":"10.1177/11206721241310629","DOIUrl":"https://doi.org/10.1177/11206721241310629","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate anatomical and functional outcomes of Faricimab therapy on a case of polypoidal choroidal vasculopathy (PCV) refractory to previous treatments.</p><p><strong>Major findings: </strong>A 56-year-old patient with PCV presenting with a large pigment epithelial detachment (PED) showed best-corrected visual acuity (BCVA) improvement, subretinal fluid (SRF) reduction and PED height reduction at 2 months follow up after a loading phase of 4 monthly Faricimab injections. The patient had previously undergone Aflibercept, Brolucizumab and photodynamic therapy (PDT) treatments with a suboptimal response.</p><p><strong>Conclusion: </strong>Despite Faricimab proving itself as an efficient alternative in a case of PCV poorly responsive to previous treatments, definite evidence still needs to be confirmed in larger studies.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721241310629"},"PeriodicalIF":1.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual lamellar keratoplasty combined with phacoemulsification and intraocular Lens implantation in a case of severe chemical burn.
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-02-06 DOI: 10.1177/11206721251318065
Luis Fernández-Vega-Cueto, Carlos Lisa, Rosa Alvarado-Villacorta, José F Alfonso
{"title":"Dual lamellar keratoplasty combined with phacoemulsification and intraocular Lens implantation in a case of severe chemical burn.","authors":"Luis Fernández-Vega-Cueto, Carlos Lisa, Rosa Alvarado-Villacorta, José F Alfonso","doi":"10.1177/11206721251318065","DOIUrl":"https://doi.org/10.1177/11206721251318065","url":null,"abstract":"<p><strong>Purpose: </strong>To present successful visual rehabilitation of a patient who suffered from a severe chemical burn by performing a new alternative surgical approach termed dual lamellar keratoplasty combined with phacoemulsification and intraocular lens implantation.</p><p><strong>Methods: </strong>A 45-year-old man with a history of caustic soda eye injury in his left eye leading to a limbal stem cell deficiency, persistent epithelial defect, corneal scarring, and progressive vision loss was admitted. No posterior segment alterations were noted. Once the ocular surface was stabilized, simple limbal epithelial transplantation was performed; however, deep corneal scarring, Descemet folds, and lens opacity were detected. Therefore, 6 months later, simultaneously Deep anterior lamellar keratoplasty (DALK) and Descemet stripping with automated endothelial keratoplasty (DSAEK), combined with cataract surgery was performed for visual rehabilitation.</p><p><strong>Results: </strong>After 15 months of follow-up, anterior segment reconstruction was achieved, and visual acuity improved from hand motion to 0.5 LogMAR unit. No intraoperative or postoperative complications were noted.</p><p><strong>Conclusion: </strong>This new modified procedure seems to be efficacy and safe for visual rehabilitation avoiding open-sky surgery-related risks by combining DALK, DSAEK and cataract surgery in a case of severe ocular burn.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251318065"},"PeriodicalIF":1.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful management of drug-resistant rhizobium radiobacter endophthalmitis: A case report.
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2025-02-03 DOI: 10.1177/11206721251318398
Po-Ying Wu, Horng-Jiun Wu
{"title":"Successful management of drug-resistant rhizobium radiobacter endophthalmitis: A case report.","authors":"Po-Ying Wu, Horng-Jiun Wu","doi":"10.1177/11206721251318398","DOIUrl":"https://doi.org/10.1177/11206721251318398","url":null,"abstract":"<p><strong>Purpose: </strong>To report a unique case of post-cataract surgery endophthalmitis caused by Ceftazidime-resistant Rhizobium radiobacter, successfully managed with timely vitrectomy and intravitreal Levofloxacin.</p><p><strong>Case report: </strong>A healthy 73-year-old man underwent phacoemulsification and posterior chamber intraocular lens implantation in his left eye. Postoperative ocular examination (OE) one day after the surgery revealed no specific findings. However, on postoperative day 6, he presented with a painful and red left eye. Diagnosed with postoperative endophthalmitis on day 8 at another hospital, he received IVI of Ceftazidime and Vancomycin before being urgently referred to our hospital on the same day. Early vitrectomy and anterior chamber irrigation were performed timely when he arrived on day 8, with cultures identifying Ceftazidime-resistant Rhizobium radiobacter, sensitive to Levofloxacin. Repeated IVI of Levofloxacin (500 mcg/0.1 ml) ensued on post-cataract operative days 13 and 18. Six months post-cataract surgery, the corrected distance visual acuity of the left eye stabilized at 20/33, and OE remained stable.</p><p><strong>Conclusion: </strong>Early vitrectomy and vitreous culture prove effective in managing postoperative endophthalmitis in drug-resistant Rhizobium radiobacter. IVI of Levofloxacin, though rare, proved to be effective in treating Ceftazidime-resistant and Levofloxacin-sensitive pathogens in our case.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251318398"},"PeriodicalIF":1.4,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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