European Journal of Ophthalmology最新文献

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Characterization and topographical analysis of choroidal caverns in young and healthy individuals. 年轻健康人脉络膜洞穴的特征和地形分析。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2024-10-15 DOI: 10.1177/11206721241289970
Serena Fragiotta, Lisa Toto, Mariacristina Parravano, Alberto Quarta, Michele Di Noia, Riccardo Sacconi, Darja Dobovsek Divjak, Federico Rissotto, Maria Sole Polito, Eliana Costanzo, Giuseppe Querques
{"title":"Characterization and topographical analysis of choroidal caverns in young and healthy individuals.","authors":"Serena Fragiotta, Lisa Toto, Mariacristina Parravano, Alberto Quarta, Michele Di Noia, Riccardo Sacconi, Darja Dobovsek Divjak, Federico Rissotto, Maria Sole Polito, Eliana Costanzo, Giuseppe Querques","doi":"10.1177/11206721241289970","DOIUrl":"https://doi.org/10.1177/11206721241289970","url":null,"abstract":"<p><strong>Purpose: </strong>To describe and clarify a possible pathogenetic origin for choroidal caverns in young healthy individuals through a topographical analysis using swept-source optical coherence tomography angiography (SS-OCTA).</p><p><strong>Methods: </strong>A cross-sectional evaluation of 44 healthy volunteers (44 eyes), aged 20-32 years with no systemic or ocular comorbidities. The topographical analysis of choroidal caverns was performed through a 15 × 15 mm volumetric scan cube using SS-OCTA (PLEX Elite 9000). The number, topographic localization within the perifovea and midperipheral retina, as well as the density of choroidal caverns in the area with the highest number, were analyzed. Factors influencing the presence of choroidal caverns were identified using a logistic regression model.</p><p><strong>Results: </strong>The overall prevalence of choroidal caverns was 18.2% in our cohort. The subjects exhibiting choroidal caverns presented a greater AXL (+1.19 mm, 95%CI: 0.09, 2.29). Areas with the highest density of caverns presented an average of 1.98 ± 1.01 caverns/mm<sup>2</sup>. On a qualitative evaluation, the area with the highest density was along the inferior vascular arcade in 6/8 (75%) eyes. The main predictor of choroidal cavern development was represented by AXL (adjusted risk ratio of 2.13, <i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>Choroidal caverns in young, healthy individuals may form due to mechanical stress in predisposed eyes, where an increased lateral and anteroposterior choroidal stretching due to globe elongation can result in the formation of these cavities. Future longitudinal studies are encouraged to understand their prognostic implications.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subthreshold micropulse laser treatment for autosomal recessive bestrophinopathy complicated by macular neovascularization. 阈下微脉冲激光治疗伴有黄斑新生血管的常染色体隐性富集蛋白病。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2024-10-15 DOI: 10.1177/11206721241291100
Rosa Buonamassa, Francesca Palumbo, Giacomo Boscia, Giacomo Scotti, Andrea Ferrara, Fabio De Vitis, Mariagrazia Pignataro, Alba Chiara Termite, Luca Landini, Giovanni Alessio, Francesco Boscia, Pasquale Viggiano
{"title":"Subthreshold micropulse laser treatment for autosomal recessive bestrophinopathy complicated by macular neovascularization.","authors":"Rosa Buonamassa, Francesca Palumbo, Giacomo Boscia, Giacomo Scotti, Andrea Ferrara, Fabio De Vitis, Mariagrazia Pignataro, Alba Chiara Termite, Luca Landini, Giovanni Alessio, Francesco Boscia, Pasquale Viggiano","doi":"10.1177/11206721241291100","DOIUrl":"https://doi.org/10.1177/11206721241291100","url":null,"abstract":"<p><strong>Purpose: </strong>To present a case of autosomal recessive bestrophinopathy (ARB) complicated by intraretinal fluid and subretinal fluid, successfully managed with navigated subthreshold micropulse laser (SML) treatment.</p><p><strong>Obervations: </strong>A 25-year-old female was referred to our clinic by her ophthalmologist due to a diagnosis of reduced vision in both eyes. The patient presented with a visual acuity of 0.9 logMAR in both eyes. Structural optical coherence tomography (OCT) revealed bilateral intraretinal fluid (IRF) and subretinal fluid (SRF), while OCT angiography (OCT-A) demonstrated bilateral macular neovascularization (MNV). Following the initiation of intravitreal therapy with anti-VEGF agents, administered via monthly injections for one year, we observed no improvement in visual acuity or resolution of IRF and SRF. SML treatment was administered to both eyes in the macular region. At the 3-month follow-up visit, OCT revealed complete resolution of IRF in the right eye and partial resolution of IRF in the left eye, and best-corrected visual acuity (BCVA) improved from 0.9 logMAR to 0.7 logMAR.</p><p><strong>Conclusions and importance: </strong>In our case, SML emerges as a promising treatment modality for patients with ARB complicated by MNV who exhibit poor response to anti-VEGF therapy. However, further prospective studies with longer follow-up periods and larger cohorts are warranted to confirm the optimal treatment strategy in ARB.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Refractive outcomes following simultaneous silicone oil removal and ciliary sulcus intraocular lens implantation. 同时摘除硅油和植入睫状沟眼内晶状体后的屈光效果。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2024-10-15 DOI: 10.1177/11206721241287255
Dezhi Zheng, Zijing Huang, Zhiying Chen, Dingguo Huang, Weiqi Chen
{"title":"Refractive outcomes following simultaneous silicone oil removal and ciliary sulcus intraocular lens implantation.","authors":"Dezhi Zheng, Zijing Huang, Zhiying Chen, Dingguo Huang, Weiqi Chen","doi":"10.1177/11206721241287255","DOIUrl":"https://doi.org/10.1177/11206721241287255","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the refractive outcomes following the combined intervention of silicon oil (SO) removal and ciliary sulcus intraocular lens (IOL) implantation in aphakic eyes after phacovitrectomy.</p><p><strong>Methods: </strong>A retrospective examination of medical records from patients who underwent a combined procedure of SO removal and ciliary sulcus IOL implantation from 2019 to 2022 was performed. The primary outcomes of interest included uncorrected distance visual acuity (UDVA), predictive error (PE) and mean absolute predictive error (MAE). Subgroup analyses were performed to compare outcomes between patients with and without intraoperative posterior capsulotomy.</p><p><strong>Results: </strong>The cohort comprised 40 eyes from 40 patients, with a mean duration of SO tamponade of 5.17 ± 1.48 months. A significant improvement in UDVA was observed from 1.58 ± 0.31 logMAR to 0.99 ± 0.31 logMAR one month postoperatively (<i>P </i>< 0.01). The PE was -0.73 ± 0.86 diopters (D), and the MAE was 0.90 ± 0.67 D, with 37.50% and 57.50% of cases achieving PE within ±0.5 D and ±1.0 D, respectively. No significant differences in UDVA, PE, or MAE were found between the capsulotomy and non-capsulotomy subgroups (all <i>P </i>> 0.05). However, a lower proportion of eyes in the capsulotomy group achieved PE within ±1.0 D compared to the non-capsulotomy group one month postoperatively (38.90% vs. 72.70%, <i>P </i>= 0.03).</p><p><strong>Conclusions: </strong>The combined procedure of SO removal and sulcus IOL implantation resulted in a mild myopic shift in postoperative refraction. Intraoperative posterior capsulotomy seems to increase the lability of postoperative refractive outcomes.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complete retinal pigment epithelium and outer retinal atrophy: Is it really an end-stage atrophy? 完全性视网膜色素上皮和外层视网膜萎缩:它真的是终末期萎缩吗?
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2024-10-15 DOI: 10.1177/11206721241290263
Juan Santamaría, Fernando Pagani, Jordi Monés
{"title":"Complete retinal pigment epithelium and outer retinal atrophy: Is it really an end-stage atrophy?","authors":"Juan Santamaría, Fernando Pagani, Jordi Monés","doi":"10.1177/11206721241290263","DOIUrl":"https://doi.org/10.1177/11206721241290263","url":null,"abstract":"<p><p>Geographic atrophy (GA), a late manifestation of age-related macular degeneration (AMD), leads to irreversible vision loss. Early identification of precursor lesions, such as incomplete and complete retinal pigment epithelium and outer retinal atrophy (iRORA and cRORA), is crucial for predicting GA formation. The latter stage has been associated with irreversible and progressive changes, and the eventual development of a dense scotoma on the compromised area. We present an 80-year-old woman with AMD in both eyes, demonstrating progressive changes over a 2-year follow-up. While the right eye developed cRORA with vision decline, the left eye exhibited unexpected restoration of the outer retinal layers within the cRORA lesion. This finding challenges the notion of \"end-stage atrophy\" in GA development and highlights the potential reversibility of early atrophic lesions. Recognizing these dynamics has implications for the development of targeted therapies aimed at preserving vision in AMD's early stages.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of postoperative outcomes after cataract surgery in patients with Juvenile Idiopathic Arthritis-Associated Uveitis. 评估青少年特发性关节炎相关葡萄膜炎患者白内障手术后的效果。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2024-10-15 DOI: 10.1177/11206721241290272
Gentian Bajraktari, Tomislav Jukić, Miro Kalauz, Martin Oroz, Andrea Radolović Bertetić, Nenad Vukojević
{"title":"Evaluation of postoperative outcomes after cataract surgery in patients with Juvenile Idiopathic Arthritis-Associated Uveitis.","authors":"Gentian Bajraktari, Tomislav Jukić, Miro Kalauz, Martin Oroz, Andrea Radolović Bertetić, Nenad Vukojević","doi":"10.1177/11206721241290272","DOIUrl":"https://doi.org/10.1177/11206721241290272","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the postoperative outcomes of cataract surgery and intraocular lens (IOL) implantation on visual outcomes and complications in pediatric patients with Juvenile Idiopathic Arthritis-Associated Uveitis.</p><p><strong>Methods: </strong>This study included 25 patients (30 eyes) with uveitis and cataracts who underwent cataract surgery. The study was conducted as a retrospective study. Patients were divided into two groups based on their preoperative treatment: those who received immunomodulatory therapy (IMT) along with systemic corticosteroids and those who received IMT in combination with a biologic therapy. Best corrected visual acuity (BCVA), intraocular pressure (IOP), central macular thickness (CMT), macular volume (MV), and postoperative complications were assessed at various time points up to 12 months. All surgeries were performed by a single surgeon.</p><p><strong>Results: </strong>Significant improvement in BCVA were observed postoperatively in both study groups, with approximately 80% of eyes showing improvement. Mean BCVA improved from 0.89 ± 0.63 to 0.37 ± 0.33 in group 1and from 0.82 ± 0.68 to 0.35 ± 0.31 in group 2 after 12 months. Postoperatively, there was a decrease in mean IOP, with no significant variance observed between the two groups. Complications were observed in 73% of cases, including posterior capsular opacification (PCO), secondary glaucoma, and macular edema (ME), but did not significantly differ between groups.</p><p><strong>Conclusion: </strong>Cataract surgery in children with uveitis associated with JIA presents significant challenges due to the risk of postoperative complications, even with adequate preoperative and postoperative care. The similar improvement in BCVA observed in both groups suggests that different systemic therapies were sufficient for satisfactory control of inflammation before and after surgery.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Refining delivery and positioning: A modified approach to FIL SSF intraocular lens implantation using the "full reverse" technique. 改进输送和定位:使用 "完全反向 "技术进行 FIL SSF 眼内透镜植入的改良方法。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2024-10-15 DOI: 10.1177/11206721241291106
Enea Chisci, Giulia Torregrossa, Salvatore Torregrossa, Alberto La Mantia
{"title":"Refining delivery and positioning: A modified approach to FIL SSF intraocular lens implantation using the \"full reverse\" technique.","authors":"Enea Chisci, Giulia Torregrossa, Salvatore Torregrossa, Alberto La Mantia","doi":"10.1177/11206721241291106","DOIUrl":"10.1177/11206721241291106","url":null,"abstract":"<p><strong>Purpose: </strong>To present a modified surgical technique for implantation of the sutureless scleral-fixated hydrophilic intraocular lens (FIL SSF).</p><p><strong>Methods: </strong>Single surgeon retrospective case series and review of surgical videos with step-by-step technique analysis. Uncorrected and best corrected visual acuity (UCVA and BCVA), refractive error (spherical equivalent), full clinical examination with intraocular pressure (IOP) measurement, endothelial cell density on corneal specular microscopy and macular optical coherence tomography (OCT) were recorded at baseline, 1, 4 and 8 weeks postoperatively.</p><p><strong>Results: </strong>The FIL SSF IOLs were successfully implanted using the so-called \"full reverse\" technique, having the lens loaded in the injector in an upside-down fashion, as opposed to IOL technical specifications. In all cases, the FIL SSF IOL was properly placed in the ciliary sulcus, well-centered and without signs of tilt. Follow up figures at 2 months are consistent with published data, confirming the potential benefits of the new implantation technique.</p><p><strong>Conclusion: </strong>In our preliminary experience, the \"full reverse\" technique of the FIL SSF IOL has proven effective in preventing incorrect IOL orientation in 100% of cases. However, larger prospective controlled studies and longer follow up are required to either support or disprove our results.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric refractive surgery: Review article. 小儿屈光手术:评论文章。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2024-10-13 DOI: 10.1177/11206721241290261
Maan Alkharashi, Moath Alowairdhi, Norah Albdaya, Rakan Alzabadin
{"title":"Pediatric refractive surgery: Review article.","authors":"Maan Alkharashi, Moath Alowairdhi, Norah Albdaya, Rakan Alzabadin","doi":"10.1177/11206721241290261","DOIUrl":"https://doi.org/10.1177/11206721241290261","url":null,"abstract":"<p><p>Refractive surgery is one of the most commonly performed elective procedures in ophthalmology; it is mostly performed in patients who are older than 18 years of age. This routine procedure has been time-tested and is proven to be both safe and effective in adults. However, little is known about the safety and efficacy of refractive surgery in pediatric patients. Granted, refractive surgery should not be used in kids merely for the purpose of avoiding spectacles wear, but it can be of valuable help is preserving vision in patients with amblyopia and accommodative esotropia who otherwise couldn't comply with traditional management options. Refractive surgery in pediatric patients is a complex and challenging field due to the unique characteristics of their developing eyes. This review article aims to provide an overview of the current literature on refractive surgery in pediatric patients, focusing on the different surgical options, the advantages and disadvantages of each procedure.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal imaging-based treatment recommendations for managing submacular hemorrhage. 基于多模态成像的白内障下出血治疗建议。
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2024-10-09 DOI: 10.1177/11206721241290267
Ramesh Venkatesh, Vishma Prabhu, Jay Chhablani
{"title":"Multimodal imaging-based treatment recommendations for managing submacular hemorrhage.","authors":"Ramesh Venkatesh, Vishma Prabhu, Jay Chhablani","doi":"10.1177/11206721241290267","DOIUrl":"https://doi.org/10.1177/11206721241290267","url":null,"abstract":"<p><p>Submacular haemorrhage (SMH) is an emergency, and the most important immediate action in the treatment of SMH is the early displacement or evacuation of subretinal heme from below the fovea, followed by simultaneous or sequential treatment of the underlying cause. Photoreceptor damage can occur immediately after the onset of SMH for a variety of reasons, including toxins released from the blood, the diffusion barrier created by the blood for oxygen delivery and nutrition to the outer retinal layers, and shearing forces on the outer retinal layers, resulting in permanent visual deterioration. A clinician's decision to treat SMH is influenced by a number of factors, including presenting visual acuity, duration of visual symptoms, SMH aetiology and characteristics, availability of intraocular gases and tissue plasminogen activator, and pars plana vitrectomy facilities. For many clinicians, the duration of visual symptoms is the most important and first consideration when planning SMH treatment. Very little emphasis is given to the SMH's imaging characteristics. Currently, there are several treatment options for SMH removal. There is a need to develop a simplified treatment algorithm for SMH that is less reliant on the patient's visual complaints, considers heme characteristics on basic retinal imaging, and has the potential to achieve uniform and predictable treatment outcomes in real-world situations. In this short article, we discuss the various factors that can assist clinicians in the management of SMH and present a simplified treatment algorithm based on the SMH's retinal imaging characteristics.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal structural changes in central serous chorioretinopathy: A multimodal imaging-based study. 中心性浆液性脉络膜视网膜病变的纵向结构变化:基于多模态成像的研究
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2024-10-03 DOI: 10.1177/11206721241287253
Niroj Kumar Sahoo, Joshua Ong, Amrish Selvam, Dmitri Maltsev, Riccardo Sacconi, Ramesh Venkatesh, Nikitha Gurram Reddy, Shivam Madan, Beatrice Tombolini, Luiz H Lima, Varsha Pramil, Giridhar Anantharaman, Antonio Marcelo Casella, Gerardo Ledesma-Gil, Nadia Waheed, Enrico Borrelli, Giuseppe Querques, Jay Chhablani
{"title":"Longitudinal structural changes in central serous chorioretinopathy: A multimodal imaging-based study.","authors":"Niroj Kumar Sahoo, Joshua Ong, Amrish Selvam, Dmitri Maltsev, Riccardo Sacconi, Ramesh Venkatesh, Nikitha Gurram Reddy, Shivam Madan, Beatrice Tombolini, Luiz H Lima, Varsha Pramil, Giridhar Anantharaman, Antonio Marcelo Casella, Gerardo Ledesma-Gil, Nadia Waheed, Enrico Borrelli, Giuseppe Querques, Jay Chhablani","doi":"10.1177/11206721241287253","DOIUrl":"https://doi.org/10.1177/11206721241287253","url":null,"abstract":"<p><strong>Purpose: </strong>To analyse the longitudinal changes in imaging parameters in eyes with acute or chronic central serous chorioretinopathy (CSCR).</p><p><strong>Methods: </strong>This was a multicentric, retrospective, longitudinal, observational study in patients with a diagnosis of CSCR and having at least 4 years of follow-up. Trend in choroidal thickness (CT), area of double layer sign (DLS), area of retinal pigment epithelium (RPE) alterations, and area of hyper-autofluorescence were analysed.</p><p><strong>Results: </strong>A total of 175 eyes of 146 patients with a mean age of 52.9 ± 12.5 years were included. Fifty-two eyes had acute and 123 had chronic CSCR at baseline. There was an overall decreasing trend of CT values during follow up (from 354.4 ± 74.8 at baseline to 343.2 ± 109.4 at final visit). There was a steady rise in DLS width and RPE alteration in the overall cohort (from 811.7 ± 760.6 microns and 3.5 ± 3.3 disc areas respectively at baseline to 1209.1 ± 1113.18 microns, 4.1 ± 3.6 disc areas at final visit). An initial rise in hyper-autofluorescent area followed by steady fall was seen in chronic CSCR. A significant positive correlation (r = 0.54, p = 0.004) was seen between change in DLS width and change in area of hyper-autofluorescence. On linear regression analysis, lower CMT and absence of intraretinal fluid at baseline were associated with greater increase in RPE abnormalities.</p><p><strong>Conclusion: </strong>Acute and chronic CSCR had different pattern of change in imaging parameters with area of RPE alterations in acute CSCR not reaching values close to that of chronic CSCR eyes even after long follow up.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinico-radiological features of optic nerve sheath schwannoma: Review and illustrative case. 视神经鞘分裂瘤的临床放射学特征:回顾与病例举例
IF 1.4 4区 医学
European Journal of Ophthalmology Pub Date : 2024-09-28 DOI: 10.1177/11206721241287575
Clare Quigley, Jessica Y Tong, Alexander S Zhang, Alkis J Psaltis, Dinesh Selva
{"title":"Clinico-radiological features of optic nerve sheath schwannoma: Review and illustrative case.","authors":"Clare Quigley, Jessica Y Tong, Alexander S Zhang, Alkis J Psaltis, Dinesh Selva","doi":"10.1177/11206721241287575","DOIUrl":"https://doi.org/10.1177/11206721241287575","url":null,"abstract":"<p><p>The optic nerve sheath is a rare site for schwannoma, to our knowledge 19 optic nerve sheath schwannoma (ONSS) cases have been reported. Difficulty can arise in diagnosis as imaging findings can be relatively non-specific. We describe a case of ONSS that mimicked orbital cavernous venous malformation pre-operatively. A 43-year-old woman presented with right subacute visual loss, reduced vision to 6/48 and signs of optic neuropathy. Endocapsular excision of the mass, which was adherent to the optic nerve, was accomplished from an endoscopic endonasal approach utilizing a 5-hand technique of retrocaruncular dissection. Histology showed spindle-shaped tumour cells with S100 positivity, consistent with ONSS. At 6 months post-operatively vision had improved to 6/6. We show that an endoscopic endonasal approach, augmented by transcaruncular retraction, can be utilized to excise ONSS with an excellent outcome. We review published cases of ONSS, including demographic and clinical features, differential diagnosis based on radiological features, and described outcomes, which are generally poor.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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