Alessandro Meduri, Giovanni William Oliverio, Laura De Luca, Davide Borroni, Rino Frisina, Pasquale Aragona
{"title":"Anterior chamber retained lens fragments: A novel approach with Nd:Yag laser.","authors":"Alessandro Meduri, Giovanni William Oliverio, Laura De Luca, Davide Borroni, Rino Frisina, Pasquale Aragona","doi":"10.1177/11206721241280740","DOIUrl":"10.1177/11206721241280740","url":null,"abstract":"<p><p>The retention of lenticular fragments (LF), either cortical or nuclear, in the anterior chamber after cataract surgery are a rare but important complication that may lead to patient discomfort and visual decrease. In this multicenter case series, we report the use of Neodymium:Yag laser to fragment LF effectively in twenty patients. MethodsMulticenter retrospective case series of nd:Yag laser fragmentation of LF in twenty eyes at different clinics discovered after cataract surgery performed through phacoemulsification and implant of intraocular lens (IOL).ConclusionEarly nd:Yag laser procedure is a good option to use for retained lenticular fragments in the anterior chamber after cataract extraction, to reduce damages to the endothelium caused by the LF, to lower patient discomfort to re-enter surgery, to minimize costs of surgical re-intervention and to avoid possible inflammatory complications given by the retained fragments that may not be reabsorbed properly and may even present several years after primary surgery leading to damages to endothelium caused by the lenticular fragments and visual disturbances.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"917-921"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142079736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fundus autofluorescence after vitrectomy with ILM peeling and subfoveal injection in diabetic macular edema.","authors":"Zofia Nawrocka, Jerzy Nawrocki","doi":"10.1177/11206721241290264","DOIUrl":"https://doi.org/10.1177/11206721241290264","url":null,"abstract":"<p><p>PurposeTo determine whether subretinal injections cause defects in the RPE that are visible on fundus autofluorescence (FAF).MethodsThis retrospective study analyzed twenty-six eyes after vitrectomy with ILM peeling and subretinal injection of balanced salt solution for diabetic macular edema (DME). FAF was performed before and 36 months after surgery. Four FAF patterns were distinguished: grade 1 -normal autofluorescence, grade 2 -one or more hyperautofluorescent spots, grade 3 -central increased autofluorescence, grade 4 -central decreased autofluorescence.ResultsVisual acuity improved from 0.18 to 0.26 Snellen (<i>p</i> = 0.03). Retinal thickness decreased (<i>p</i> = 0.01). The injection site would not be possible to spot on postoperative FAF without reviewing surgical videos. Grade 1 pattern was visible in 31% operated and 36% fellow eyes, Grade 2 pattern was observed in 11% operated and in 43% fellow eyes, Grade 3 pattern in 31% operated and in 14% fellow eyes and grade 4 pattern in 31% operated and in 14% fellow eyes.ConclusionNo abnormal FAF patterns were observed at the subretinal injection sites. ILM peeling likely decreases the pressure required to perform the injection and protects the RPE from iatrogenic damage. Anomalous autofluorescence patterns are most likely associated with long-standing disease.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":"35 3","pages":"1036-1043"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anti-complement intravitreal agents for geographic atrophy: A missed opportunity for European patients?","authors":"Paolo Lanzetta","doi":"10.1177/11206721241310626","DOIUrl":"https://doi.org/10.1177/11206721241310626","url":null,"abstract":"","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":"35 3","pages":"NP63-NP64"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yun-Hee Choi, Nayoon Park, Seul-Ah Park, Juyang Kim, Jaehak Jung, Yoon-Hyeong Choi, Dong Hyun Kim
{"title":"Detection of microplastics in pterygium tissue: Implications for environmental hazards.","authors":"Yun-Hee Choi, Nayoon Park, Seul-Ah Park, Juyang Kim, Jaehak Jung, Yoon-Hyeong Choi, Dong Hyun Kim","doi":"10.1177/11206721241310467","DOIUrl":"https://doi.org/10.1177/11206721241310467","url":null,"abstract":"<p><p>PurposeThis study aimed to report a case of microplastics (MPs) detection in a pterygium patient's tissue.Case reportA pterygium specimen was obtained from the right eye of a 43-year-old woman by surgical removal of a recurred pterygium. The number, morphology, and material type of the MPs in pterygium were identified using Raman microscopy and scanning electron microscopy. Ten MPs were detected in the pterygium, which corresponded to polyethylene (PE) (n = 7), polystyrene (PS) (n = 2), and polypropylene (PP) (n = 1). The size of MPs ranged from 5-9 µm (n = 5, PE or PS), 10-19 µm (n = 4, PE), and 50-99 µm (n = 1, PP). All MPs were transparent and irregular fragments.ConclusionsThis study demonstrated the detection of MPs in the pterygium tissue. Our findings suggest that environmental hazards, such as MP, may be commonly exposed to the ocular surface.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":"35 3","pages":"NP10-NP13"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramin Salouti, Ali Azizi, Hesam Hashemian, Masoud Khorrami-Nejad, Qassim Alkhafaji, Kia Salouti, Maryam Ghoreyshi, M Hossein Nowroozzadeh
{"title":"A comparison of white-to-white measurements obtained by Anterion AS-OCT versus three optical devices in refractive surgery candidates.","authors":"Ramin Salouti, Ali Azizi, Hesam Hashemian, Masoud Khorrami-Nejad, Qassim Alkhafaji, Kia Salouti, Maryam Ghoreyshi, M Hossein Nowroozzadeh","doi":"10.1177/11206721241281876","DOIUrl":"10.1177/11206721241281876","url":null,"abstract":"<p><p>Background and ObjectivesTo assess the agreement between Anterion AS-OCT and three optical devices in measuring the white-to-white (WTW) diameter in candidates for refractive surgery.MethodsIn this cross-sectional prospective study, 129 right eyes of 129 normal individuals underwent consecutive scans with the Anterion, the Pentacam AXL, the IOLMaster 700, and the Orbscan IIz. Mean difference (MD), 95% limits of agreement (LoA), and concordance correlation coefficient (CCC) were calculated to assess agreement and interchangeability.ResultsThe mean age of participants was 30.4 ± 5.9 (range: 21-47) years. The mean WTW distance measured by the different instruments was as follows: 12.00 ± 0.42 mm (range, 10.57 to 13.05) using the Anterion, 11.87 ± 0.34 (11.10 to 12.80) using the Pentacam, 12.12 ± 0.44 (11.00 to 13.30) using the IOLMaster, and 11.73 ± 0.37 (11.00 to 13.10) using the Orbscan. The MD and 95% LoA for Anterion vs. Pentacam, IOLMaster, or Orbscan were [0.11; -0.31 to 0.54 mm], [-0.13; -0.93 to 0.66], and [0.25; -0.28 to 0.78], respectively. The corresponding CCCs were 0.803, 0.514, and 0.631.ConclusionsThis study found weak agreement between Anterion and Pentacam AXL, IOLMaster 700, and Orbscan IIz devices regarding WTW distance measurements in refractive surgery candidates. Therefore, it is not recommended to use Anterion's WTW measurements interchangeably with the other three devices, particularly for phakic intraocular lens sizing.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"902-909"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cyuan Yi Yeh, Kuan Chieh Chen, Yen Ju Chen, Sheng Fu Cheng
{"title":"Accelerated versus conventional corneal collagen cross-linking for keratoconus: A meta-analysis of randomized controlled trials.","authors":"Cyuan Yi Yeh, Kuan Chieh Chen, Yen Ju Chen, Sheng Fu Cheng","doi":"10.1177/11206721241298317","DOIUrl":"10.1177/11206721241298317","url":null,"abstract":"<p><p>PurposeTo systematically compare the effectiveness of conventional corneal collagen cross-linking (CCXL) protocols and accelerated corneal collagen cross-linking (ACXL) protocols in cases with progressive keratoconus.MethodsThe Cochrane library, EMBASE, MEDLINE, PubMed, and Web of Science databases were searched for randomized controlled trials (RCTs). Outcomes were clinical results and changes in corneal properties. Standardized mean differences (SMD) and 95% confidence interval (CI) were used to estimate the clinical consequences. All outcomes were distributed by different follow-up durations (6 months, 12 months, and > 12 months). We also compared maximum keratometry (Kmax) and best spectacle-corrected visual acuity (BCVA) in subgroups, which were categorized by the discrepant impregnation time period of riboflavin.ResultsWe included 14 RCTs that met the eligibility criteria in this meta-analysis. At the last follow-up, CCXL was superior in postoperative change in demarcation line (SMD: -1.573; 95% CI: -2.897 to -0.248) and in Kmax (SMD:0.302; 95% CI: 0.071 to 0.533), whereas ACXL provided a significantly lower reduction in central corneal thickness (SMD: 0.498; 95% CI: 0.125 to 0.871). No differences in the changes in uncorrected visual acuity, BCVA, manifest refraction spherical equivalent, corneal biomechanical properties, and the endothelial cell density were found among both groups.ConclusionCCXL was superior to ACXL in greater corneal flattening and deeper demarcation line, while ACXL seemed to cause less reduction in CCT and allow for earlier UDVA stability. To clearly define the comparative safety and clinical consequences of the different regimens of CXL, more RCTs are required.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"785-798"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142617356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful management of drug-resistant rhizobium radiobacter endophthalmitis: A case report.","authors":"Po-Ying Wu, Horng-Jiun Wu","doi":"10.1177/11206721251318398","DOIUrl":"10.1177/11206721251318398","url":null,"abstract":"<p><p>PurposeTo report a unique case of post-cataract surgery endophthalmitis caused by Ceftazidime-resistant Rhizobium radiobacter, successfully managed with timely vitrectomy and intravitreal LevofloxacinCase reportA healthy 73-year-old man underwent phacoemulsification and posterior chamber intraocular lens implantation in his left eye. Postoperative ocular examination (OE) one day after the surgery revealed no specific findings. However, on postoperative day 6, he presented with a painful and red left eye. Diagnosed with postoperative endophthalmitis on day 8 at another hospital, he received IVI of Ceftazidime and Vancomycin before being urgently referred to our hospital on the same day. Early vitrectomy and anterior chamber irrigation were performed timely when he arrived on day 8, with cultures identifying Ceftazidime-resistant Rhizobium radiobacter, sensitive to Levofloxacin. Repeated IVI of Levofloxacin (500 mcg/0.1 ml) ensued on post-cataract operative days 13 and 18. Six months post-cataract surgery, the corrected distance visual acuity of the left eye stabilized at 20/33, and OE remained stable.ConclusionEarly vitrectomy and vitreous culture prove effective in managing postoperative endophthalmitis in drug-resistant Rhizobium radiobacter. IVI of Levofloxacin, though rare, proved to be effective in treating Ceftazidime-resistant and Levofloxacin-sensitive pathogens in our case.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"NP42-NP45"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation between macular sensitivity and kidney function in patients with diabetes.","authors":"Antoaneta Adžić Zečević, Valentina Vujović Kalinić, Zorica Potpara, Ksenija Zečević","doi":"10.1177/11206721241286563","DOIUrl":"10.1177/11206721241286563","url":null,"abstract":"<p><p>PurposeThe aim of this study is to investigate the correlation between kidney function in patients with diabetes and macular sensitivity at central 10° using microperimetry.MethodsA cross-sectional study was carried out on 30 diabetic patients (58 eyes). A full-threshold microperimetry of the central 10° of retina (the macula) was performed on all subjects, consisting of 37 measurement points, using a 4-2 representation strategy. Macular sensitivity was expressed as the average threshold value in decibels for the entire field tested. The correlation between macular sensitivity and GFR, as well as microalbuminuria, blood glucose and HbA1c, was calculated using Pearson correlation rank.ResultsA significant positive correlation was observed between GFR and macular sensitivity among both male and female study subjects. For male participants, the correlation was measured to r([16]) = [.615], <i>p</i> = [<.007] and r([15]) = [.844], <i>p</i> = [<.001] for the left and right eyes, respectively. As for female participants, the correlation was r ([9]) = [.903], <i>p</i> = [<.001] and r([10]) = [.941], <i>p</i> = [<.001] for the left and right eyes, respectively. The correlation between macular sensitivity and the following variables was statistically insignificant: microalbuminuria, blood glucose, and HbA1c.ConclusionDespite intact visual acuity measured on standard ophthalmic examination, patients with impaired kidney function had decreased macular sensitivity. This emphasizes the importance of microperimetry in preventative care and detection of early signs of diabetic retinopathy. Furthermore, we should consider the use of microperimetry as an auxiliary tool for monitoring kidney function in diabetics.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1013-1019"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Chen, Hua Fan, Qingwen Yu, Ting Tang, Xuhan Tong, Siqi Hu, Yao You, Shenghui Zhang, Chen Chen, Jiake Tang, Hu Wang, Xinyan Fu, Xingwei Zhang, Mingwei Wang, Yongran Cheng
{"title":"Estimates and trends in the global burden of glaucoma influenced by metabolic risk factors from Global Burden of Disease Study between 1990 to 2019.","authors":"Juan Chen, Hua Fan, Qingwen Yu, Ting Tang, Xuhan Tong, Siqi Hu, Yao You, Shenghui Zhang, Chen Chen, Jiake Tang, Hu Wang, Xinyan Fu, Xingwei Zhang, Mingwei Wang, Yongran Cheng","doi":"10.1177/11206721241298022","DOIUrl":"10.1177/11206721241298022","url":null,"abstract":"<p><p>PurposeGlaucoma is an irreversible eye disease that causes blindness, which not only causes visual impairment and economic burden to patients, but also increases the social burden. This study aimed to estimate the global burden of glaucoma due to metabolic risk over the past 30 years.MethodsThe number and rate of deaths, disability-adjusted life years (DALYs), and age-standardized rates (ASRs) for metabolic risk factors-induced glaucoma were extracted. The estimated annual percentage changes (EAPCs) for ASRs were calculated using a generalized linear model with a Gaussian distribution to quantify the temporal trends in the global burden of metabolic risk factor-attributed glaucoma. The strength and direction of the association between the sociodemographic index (SDI) and the DALY rate were measured using Spearman's rank-order correlation.ResultsApproximately 0.07% of the global DALYs of glaucoma in 1990 were associated with metabolic risk factors, which increased to 0.1% in 2019. From 1990 to 2019, the global DALY cases of glaucoma caused by metabolic risk factors and the global burden of DALYs increased, whereas the DALY rate decreased with a higher SDI regional grade. The ASR of glaucoma disability loss years with a metabolic high risk increased with age, reaching the highest in the >85-year-old age group.ConclusionThe burden of glaucoma caused by metabolic risk factors has increased over the past three decades, especially in regions with a low SDI and in old-age groups.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"972-979"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142617377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paras P Shah, Samuel M Gelnick, Daniel Zhu, Jules A Winokur, Prachi Dua, Howard D Pomeranz, Thomas Perera, Matthew G Gorski
{"title":"Efficacy of a portable non-mydriatic fundus camera for \"rule-out papilledema\" consultations: A prospective study.","authors":"Paras P Shah, Samuel M Gelnick, Daniel Zhu, Jules A Winokur, Prachi Dua, Howard D Pomeranz, Thomas Perera, Matthew G Gorski","doi":"10.1177/11206721241292105","DOIUrl":"10.1177/11206721241292105","url":null,"abstract":"<p><p>PurposeOphthalmology is frequently consulted to \"rule-out papilledema.\" We assessed the efficacy of a portable, non-mydriatic fundus camera in detecting optic disc edema in the inpatient and emergency room settings during \"rule-out papilledema\" consultations, comparing to the gold standard dilated fundus examination (DFE).MethodsThis prospective, blinded, cohort study included 124 non-mydriatic fundus photographs (62 patients) that were obtained over the 11-month enrollment period. The images, along with a brief clinical history, were evaluated independently by an attending neuro-ophthalmologist (NO), general ophthalmologist (GO), emergency room (ER) physician, and ophthalmology resident (OR), for the presence of disc edema and indication for consultation. Results were compared to DFE. Sensitivity, specificity, and area under receiver operating characteristic (ROC) curves were determined to evaluate the efficacy of the camera.ResultsOn DFE, disc edema was present in 51 eyes (41.1%). Compared to DFE, NO assessment had the greatest combined sensitivity (84.3%) and specificity (97.3%) for the detection of disc edema, followed by that of GO (sensitivity 77.4%, specificity 100%), OR (sensitivity 96.1%, specificity 80.8%), and ER clinician (sensitivity 68.6%, specificity 89.0%). Areas under ROC curves for NO, GO, OR, and ER physician were all statistically significant for the detection of disc edema (0.908, <i>P</i> < 0.001; 0.892, <i>P</i> < 0.001; 0.885, <i>P</i> < 0.001; 0.788, <i>P</i> < 0.001, respectively).ConclusionClinicians were able to correctly identify optic disc edema using non-mydriatic fundus photography. Non-mydriatic fundus photography may be an effective inpatient or telemedicine tool to assess for optic disc edema.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"1122-1129"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}