European Journal of Ophthalmology最新文献

Dual lamellar keratoplasty combined with phacoemulsification and intraocular Lens implantation in a case of severe chemical burn.

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-02-06 DOI: 10.1177/11206721251318065

Luis Fernández-Vega-Cueto, Carlos Lisa, Rosa Alvarado-Villacorta, José F Alfonso

{"title":"Dual lamellar keratoplasty combined with phacoemulsification and intraocular Lens implantation in a case of severe chemical burn.","authors":"Luis Fernández-Vega-Cueto, Carlos Lisa, Rosa Alvarado-Villacorta, José F Alfonso","doi":"10.1177/11206721251318065","DOIUrl":"https://doi.org/10.1177/11206721251318065","url":null,"abstract":"Purpose: To present successful visual rehabilitation of a patient who suffered from a severe chemical burn by performing a new alternative surgical approach termed dual lamellar keratoplasty combined with phacoemulsification and intraocular lens implantation.Methods: A 45-year-old man with a history of caustic soda eye injury in his left eye leading to a limbal stem cell deficiency, persistent epithelial defect, corneal scarring, and progressive vision loss was admitted. No posterior segment alterations were noted. Once the ocular surface was stabilized, simple limbal epithelial transplantation was performed; however, deep corneal scarring, Descemet folds, and lens opacity were detected. Therefore, 6 months later, simultaneously Deep anterior lamellar keratoplasty (DALK) and Descemet stripping with automated endothelial keratoplasty (DSAEK), combined with cataract surgery was performed for visual rehabilitation.Results: After 15 months of follow-up, anterior segment reconstruction was achieved, and visual acuity improved from hand motion to 0.5 LogMAR unit. No intraoperative or postoperative complications were noted.Conclusion: This new modified procedure seems to be efficacy and safe for visual rehabilitation avoiding open-sky surgery-related risks by combining DALK, DSAEK and cataract surgery in a case of severe ocular burn.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251318065"},"PeriodicalIF":1.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Real-world evidence of anti-VEGF therapies in patients with neovascular age-related macular degeneration in Italy: The RADIANCE study.

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-02-03 DOI: 10.1177/11206721241310628

Mariacristina Parravano, Francesco Viola, Massimo Nicolò, Stela Vujosevic, Laura Bianchino, Emilia Sicari, Giulia Villa, Paolo Lanzetta

{"title":"Real-world evidence of anti-VEGF therapies in patients with neovascular age-related macular degeneration in Italy: The RADIANCE study.","authors":"Mariacristina Parravano, Francesco Viola, Massimo Nicolò, Stela Vujosevic, Laura Bianchino, Emilia Sicari, Giulia Villa, Paolo Lanzetta","doi":"10.1177/11206721241310628","DOIUrl":"https://doi.org/10.1177/11206721241310628","url":null,"abstract":"Purpose: Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss, particularly neovascular AMD (nAMD). This study aimed to investigate the real-world treatment patterns, effectiveness, and safety of intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapies for anti-VEGF naïve nAMD patients in Italy.Methods: RADIANCE is a retrospective, observational, multicenter cohort study conducted at 13 clinical sites across Italy. The study enrolled all consecutive patients with nAMD, naïve to any intraocular anti-VEGF treatment and who initiated therapy with aflibercept, ranibizumab, or bevacizumab between January 2017 and November 2018. The primary objective of this study was to evaluate changes in visual acuity (VA) 52 weeks after initiating treatment with anti-VEGF.Results: A total of 405 patients were enrolled; of these, 263 patients had at least two VA measurements and were included in the completer analysis (CA) set. At 52 weeks, the median VA change from baseline in the CA set was +1 letter, with 41.1% showing ≥ 5-letter improvement. Stratified by anti-VEGF agent, no statistically significant differences were observed. Overall, patients received a median of 5.0 (25th-75th percentile 3-6) injections of the initial anti-VEGF agent during the first year. Patients receiving ≥ 6 injections in the first year showed better VA outcomes. Undertreatment was evident at decreasing injection frequency over time.Conclusion: The results of the RADIANCE study suggest an overall moderate effectiveness after 1 year of treatment with anti-VEGF in naïve patients with nAMD in Italy. Real-world outcomes demonstrated suboptimal treatment with no significant differences among anti-VEGF agents.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721241310628"},"PeriodicalIF":1.4,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful management of drug-resistant rhizobium radiobacter endophthalmitis: A case report.

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-02-03 DOI: 10.1177/11206721251318398

Po-Ying Wu, Horng-Jiun Wu

{"title":"Successful management of drug-resistant rhizobium radiobacter endophthalmitis: A case report.","authors":"Po-Ying Wu, Horng-Jiun Wu","doi":"10.1177/11206721251318398","DOIUrl":"https://doi.org/10.1177/11206721251318398","url":null,"abstract":"Purpose: To report a unique case of post-cataract surgery endophthalmitis caused by Ceftazidime-resistant Rhizobium radiobacter, successfully managed with timely vitrectomy and intravitreal Levofloxacin.Case report: A healthy 73-year-old man underwent phacoemulsification and posterior chamber intraocular lens implantation in his left eye. Postoperative ocular examination (OE) one day after the surgery revealed no specific findings. However, on postoperative day 6, he presented with a painful and red left eye. Diagnosed with postoperative endophthalmitis on day 8 at another hospital, he received IVI of Ceftazidime and Vancomycin before being urgently referred to our hospital on the same day. Early vitrectomy and anterior chamber irrigation were performed timely when he arrived on day 8, with cultures identifying Ceftazidime-resistant Rhizobium radiobacter, sensitive to Levofloxacin. Repeated IVI of Levofloxacin (500 mcg/0.1 ml) ensued on post-cataract operative days 13 and 18. Six months post-cataract surgery, the corrected distance visual acuity of the left eye stabilized at 20/33, and OE remained stable.Conclusion: Early vitrectomy and vitreous culture prove effective in managing postoperative endophthalmitis in drug-resistant Rhizobium radiobacter. IVI of Levofloxacin, though rare, proved to be effective in treating Ceftazidime-resistant and Levofloxacin-sensitive pathogens in our case.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251318398"},"PeriodicalIF":1.4,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One-year results of double site versus single site rigid probe viscotrabeculotomy in primary congenital glaucoma.

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-01-29 DOI: 10.1177/11206721241310269

Eman M El Hefney, Eman A Atallah, Hanem Kishk, Ahmed S Elwehidy, Dina Abd Elfattah

{"title":"One-year results of double site versus single site rigid probe viscotrabeculotomy in primary congenital glaucoma.","authors":"Eman M El Hefney, Eman A Atallah, Hanem Kishk, Ahmed S Elwehidy, Dina Abd Elfattah","doi":"10.1177/11206721241310269","DOIUrl":"https://doi.org/10.1177/11206721241310269","url":null,"abstract":"Study purpose: to compare single- site viscotrabeculotomy in one eye and double-site rigid probe viscotrabeculotomy in the other eye of the same patient with Primary congenital glaucoma to evaluate the effect of the extent of angle treatment on success rate in the study's locality.Patients and methods: This prospective randomized study included 70 eyes of 35 children diagnosed with bilateral PCG who attended Mansoura Ophthalmic Center from June 2021 to July 2023. For each patient, one eye underwent single-site rigid probe viscotrabeculotomy (Group S: 35 eyes) and the fellow eye underwent double- site rigid probe viscotrabeculotomy (Group D: 35 eyes). At one-year follow up, complete success was defined as IOP >5 mmHg and ≤16 mmHg without any further IOP-lowering medications and qualified success when IOP ≤16 mmHg with using IOP-lowering medications. Failure was defined as IOP more than 16 mmHg despite the use of IOP-lowering medications, the need for other glaucoma surgery to control IOP or hypotony.Results: Single-site rigid probe viscotrabeculotomy showed a one-year complete success rate of 88.57% and for double-site viscotrabeculotomy was 91.43% but the difference was not statistically significant (p-value 0.9). There were no major complications in both groups, hyphema was the most common complication and was self-limited.Conclusion: Single-site viscotrabeculotomy shows comparable results to double-site viscotrabeculotomy in PCG preserving more than half of the angle in the former for a second possible angle surgery in recurrent cases.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721241310269"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143058468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Value of MRI-based radiomics models for predicting visual outcome in patients with MOG-optic neuritis: A preliminary study.

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-01-28 DOI: 10.1177/11206721251315784

Buhuan Zhang, Xiaoxia Chen, Yuru Dong, Muqing Liu, Sihan Du, Wenjuan Han, Ju Ye, Guisheng Wang

{"title":"Value of MRI-based radiomics models for predicting visual outcome in patients with MOG-optic neuritis: A preliminary study.","authors":"Buhuan Zhang, Xiaoxia Chen, Yuru Dong, Muqing Liu, Sihan Du, Wenjuan Han, Ju Ye, Guisheng Wang","doi":"10.1177/11206721251315784","DOIUrl":"https://doi.org/10.1177/11206721251315784","url":null,"abstract":"Purpose: To investigate the predictive value of MRI-based radiomics models for the recovery of visual acuity after 12 months in patients with acute phase MOG-optic neuritis(MOG-ON).Materials and methods: Clinical and MRI imaging data were collected consecutively from January 2021 to April 2022 from patients with acute stage MOG-ON, and the visual acuity of patients were followed up after 12 months. After stratified random sampling, patients were divided into training and test sets, and prediction models based on CE-T1WI, FS-T2WI, and combined CE-T1WI and FS-T2WI were developed.Results: A total of 34 eyes were included, the visual acuity recovery group included 26 eyes, and the visual acuity non-recovery group included 8 eyes. The training set included 23 eyes (18 from the visual acuity recovery group and 5 from the visual acuity non-recovery group) and the test set included 11 eyes (8 from the visual acuity recovery group and 3 from the visual acuity non-recovery group). The differences in gender, age, proportion of patients with visual acuity recovery, and lesion length between the training and test sets were not statistically significant(P＜0.05). The CE-T1WI-based radiomics model had highest predictive efficacy for visual acuity recovery after 12 months in patients with MOG-ON (AUC = 0.917), followed by the combined CE-T1WI and FS-T2WI-based radiomics model (AUC = 0.838), while the FS-T2WI-based radiomics model had the worst predictive efficacy (AUC = 0.583).Conclusions: MRI-based radiomics models have high value in predicting visual acuity recovery after 12 months in patients with acute stage MOG-ON, especially CE-T1WI.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251315784"},"PeriodicalIF":1.4,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orbital textiloma: Two case reports and a literature review.

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-01-27 DOI: 10.1177/11206721251316615

Mostafa M Diab, Ahmed A Ismail, Adel Alsuhaibani

引用次数: 0

Anterior chamber morphological and refractive outcomes following phacoemulsification in pseudoexfoliative eyes: A case-control study.

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-01-23 DOI: 10.1177/11206721241310345

Bruna Cunha, Pedro Gil, Catarina Barão, Diogo Hipólito-Fernandes, Vítor Maduro, João Feijão, Nuno Alves

{"title":"Anterior chamber morphological and refractive outcomes following phacoemulsification in pseudoexfoliative eyes: A case-control study.","authors":"Bruna Cunha, Pedro Gil, Catarina Barão, Diogo Hipólito-Fernandes, Vítor Maduro, João Feijão, Nuno Alves","doi":"10.1177/11206721241310345","DOIUrl":"https://doi.org/10.1177/11206721241310345","url":null,"abstract":"Purpose: To compare changes in angle morphology, anterior chamber depth (ACD) and refractive prediction error (PE) after phacoemulsification between pseudoexfoliative (PEX) and non-PEX eyes.Methods: Prospective case-control study of eyes submitted to cataract surgery. Biometric data and angle parameters - Anterior Chamber Angle (ACA), Angle Opening Distance (AOD), Scleral Spur Angles (SSA) and Trabecular Iris Space Area (TISA) - were measured preoperatively and 1-month postoperatively through swept-source anterior segment optical coherence tomography. Postoperative refractive prediction error (PE) was calculated using an optimized A-constant and the Kane formula.Results: Sixty eyes (30 PEX and 30 non-PEX) of 60 patients were included. Preoperative angle analysis revealed a lower ACA, AOD, SSA and TISA in PEX group (p < 0.05), without biometric differences (p > 0.05). A tendency for a higher magnitude of morphometric angle changes in PEX eyes was observed, with a superior increase of SSA at 500 µm (0°) and TISA at 750 µm (0°) (p = 0.030 and p = 0.041, respectively). The anterior chamber deepened in both groups (p = 0.01), with arithmetic and percentile change being higher in PEX group (p = 0.017 and p = 0.047, respectively). A significant PE hyperopic shift was observed (p = 0.035) only in PEX group.Conclusions: Pseudoexfoliative eyes with cataract have narrower angles, revealing a tendency for higher angle opening after surgery, along with an increased ACD deepening compared to non-PEX eyes, which may be explained by PEX-associated zonular laxity. Moreover, a significant hyperopic shift was observed in PEX eyes, a relevant fact to take into consideration when selecting intraocular lens power.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721241310345"},"PeriodicalIF":1.4,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety and efficacy of a modified suprachoroidal silicone tube shunt implant in primary open angle and pseudo-exfoliative glaucoma. 改良的脉络膜上硅胶管分流术治疗原发性开角型和假剥脱性青光眼的安全性和有效性。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-01-22 DOI: 10.1177/11206721251314532

Nikoloz Labauri, Tekla Mamageishvili, Ana Vachiberidze, Monika Zalinian, Lika Svanadze, Luka Sabanadze, Orkhan Huseynov, Tamar Sulkhanishvili, Maka Labauri, Marine Shakarashvili, Mikheil Omiadze, Yoram Solberg

{"title":"Safety and efficacy of a modified suprachoroidal silicone tube shunt implant in primary open angle and pseudo-exfoliative glaucoma.","authors":"Nikoloz Labauri, Tekla Mamageishvili, Ana Vachiberidze, Monika Zalinian, Lika Svanadze, Luka Sabanadze, Orkhan Huseynov, Tamar Sulkhanishvili, Maka Labauri, Marine Shakarashvili, Mikheil Omiadze, Yoram Solberg","doi":"10.1177/11206721251314532","DOIUrl":"https://doi.org/10.1177/11206721251314532","url":null,"abstract":"Purpose: To assess the safety and efficacy of a modified suprachoroidal silicone tube (SST) shunt in patients with primary open-angle glaucoma (POAG) and pseudo-exfoliative glaucoma (PXG) in this experimental study.Methods: In this single-center, retrospective longitudinal data analysis 66 eyes of 59 patients having POAG and PXG were included and treated with modified SST shunt in combination with cataract or as a stand-alone procedure. Pre- and postoperative intraocular pressure (IOP), best corrected visual acuity (BCVA), C/D ratio and ocular adverse events (AEs) were assessed in all participants.Results: The average follow-up period was 18.56 ± 7.93 months. Mean baseline IOP reduced from 27.02 ± 5.43 mmHg to 13.23 ± 3.70 mmHg (p < 0.001). Mean number of ocular hypotensive medications reduced from 3.17 ± 0.89 to 1.83 ± 1.44 (p < 0.001). BCVA remained stable in 49 eyes (74.2%) throughout the follow-up period. Mean baseline BCVA of 0.73 ± 0.27 slightly declined to 0.68 ± 0.30 at the final follow-up (p < 0.001). Three adverse events of special interest (AESI) were observed hypotonic maculopathy, anterior chamber inflammation with pupillary membranes, and macular edema. None of these events was related to the SST shunt. Other complications such as intra and early postoperative hyphema in 3 and tube-iris contact causing slight corectopia in 2 cases were noted.Conclusions: The surgical technique and device studied in this work demonstrated a good safety profile and signal of efficacy. This device may serve as a bridge between minimally invasive glaucoma surgeries (MIGS) and conventional filtering or episcleral tube shunt surgeries. A larger scale prospective trial is planned.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251314532"},"PeriodicalIF":1.4,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A face-to-face survey on the practice of ophthalmic clinicians in the management of dry eye disease in patients undergoing cataract surgery. 面对面调查眼科临床医生在白内障手术患者干眼病管理中的做法。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-01-21 DOI: 10.1177/11206721241312249

Khayam Naderi, Laura Maubon, Chun Fung Jeffrey Lam, Harry Roberts, Vishal Shah, Darshak S Patel, David O'Brart

{"title":"A face-to-face survey on the practice of ophthalmic clinicians in the management of dry eye disease in patients undergoing cataract surgery.","authors":"Khayam Naderi, Laura Maubon, Chun Fung Jeffrey Lam, Harry Roberts, Vishal Shah, Darshak S Patel, David O'Brart","doi":"10.1177/11206721241312249","DOIUrl":"https://doi.org/10.1177/11206721241312249","url":null,"abstract":"Introduction: Dry eye disease (DED) can impact the accuracy of biometry measurements prior to cataract surgery (CS), influence visual performance post-CS, and can be exacerbated by CS. We performed a survey to evaluate the DED practice of clinicians directly caring for CS patients.Design: Prospective face-to-face survey.Method: Face-to-face survey consisting of 12 questions relating to CS clinicians' estimations of DED pre- and post-CS, dry eye tests performed, and the management of DED.Result: There were one hundred and twenty-seven responders (39% consultants, 37% trainees/fellows, 8% associate specialists, 6% specialty doctors, 8% optometrists, 2% nurse specialists), with a 100% response rate. Sixty-seven percent routinely assessed for DED pre-CS, with 81% anticipating mild to moderative negative effects of CS on DED. Approximately 75% estimated that over 10% of pre-operative patients had asymptomatic DED, with another 10% or more suffering symptomatic DED. Almost 80% estimated that 10% or more of patients suffered DED post-CS. More DED tests were performed pre- compared to post-operatively (p = 0.02). More consultants performed dry eye tests post-operatively compared to non-consultants (p = 0.02). Most common treatment options included lubricating drops (95%), lid hygiene (75%) and night ointment/gels (54%). Seventy-six percent of surgeons performing CS stated they coated the ocular surface with an ophthalmic visco-surgical device and 34% limited intra-operative light exposure peri-operatively to limit DED.Discussion: Despite the anticipated negative effects of CS on DED, 1 in 3 clinicians in our survey were not assessing routinely for DED prior to CS, and fewer dry eye tests were performed post-operatively compared to pre-surgery.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721241312249"},"PeriodicalIF":1.4,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

H syndrome with bilateral choroidal osteoma: Coincidence or association? H综合征伴双侧脉络膜骨瘤：巧合还是关联？

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-01-21 DOI: 10.1177/11206721251314531

Ayna Sariyeva Ismayilov, Derya Doğanay, Mahmut Oğuz Ulusoy, Okan Akacı, Ali Topak, Muhsin Elmas

{"title":"H syndrome with bilateral choroidal osteoma: Coincidence or association?","authors":"Ayna Sariyeva Ismayilov, Derya Doğanay, Mahmut Oğuz Ulusoy, Okan Akacı, Ali Topak, Muhsin Elmas","doi":"10.1177/11206721251314531","DOIUrl":"https://doi.org/10.1177/11206721251314531","url":null,"abstract":"Purpose: To report a case with bilateral corneal arcus and bilateral choroidal osteoma associated with H syndrome.Methods: Descriptive case report.Results: A 16-year-old girl with H syndrome was followed up in the pediatric nephrology clinic for chronic renal failure and was consulted to the ophthalmology clinic. She had low vision for more than 5 years. Slit lamp examination revealed bilateral corneal arcus . Lens and iris were normal. Axial length was 19.99 mm in the right eye and 21.85 mm in the left eye. A bilateral orange-yellow plaque was noted in the posterior pole in the funduscopic examination. Fundus autofluorescence (FAF) showed a bilateral diffuse macular hipoautofluorescence area in correspondence with the decalcified portion of the mass. Optical coherence tomography (OCT) showed a bilateral choroidal mass with a dome-shaped pushing effect on the overlying retina and damage to the outer layers of the retina. Fluorescein angiography (FA) with bilateral patchy diffuse late hyperfluorescence and B scan ultrasonography showed a bilateral solid highly reflective choroidal mass with acoustic shadowing. Orbital computerized tomography (CT) scans showed bilateral hyperdense plaques in the posterior pole. A diagnosis of choroidal osteomas was made for both eyes.Conclusions: This report presents a case with bilateral corneal arcus and bilateral choroidal osteoma associated with H syndrome that has not been previously reported in the literature. Patients diagnosed with this syndrome should undergo routine eye examination, and due to the progressive nature of histiocytosis, they should also be followed closely ophthalmologically.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251314531"},"PeriodicalIF":1.4,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0