European Journal of Ophthalmology最新文献_第2页

A case of orbital rheumatoid nodule. 眼眶类风湿性结节1例。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-03-23 DOI: 10.1177/11206721251324240

Irene Bermudez-Castellanos, Silvia Hernández García, Patricia Callejo Perez, Alicia Galindo-Ferreiro

引用次数: 0

Conjunctival impression cytology and tear film analysis in early-stage Parkinson's disease. 早期帕金森病的结膜印模细胞学和泪膜分析。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-03-19 DOI: 10.1177/11206721251330472

Ali Tezcan, Refik Oltulu, Pembe Oltulu, Ali Osman Gundogan, Selman Belviranli

{"title":"Conjunctival impression cytology and tear film analysis in early-stage Parkinson's disease.","authors":"Ali Tezcan, Refik Oltulu, Pembe Oltulu, Ali Osman Gundogan, Selman Belviranli","doi":"10.1177/11206721251330472","DOIUrl":"https://doi.org/10.1177/11206721251330472","url":null,"abstract":"PurposeWe aimed to evaluate conjunctival impression cytology (CIC) findings, tear parameters, and ocular surface in early-stage Parkinson's patients and compare the results with the control group.MethodsThis cross-sectional comparative study included 49 early-stage Parkinson's Disease (PD) patients and 45 healthy individuals as a control group. Clinical staging of Parkinson's patients was performed according to the Hoehn-Yahr Scale. Those with stages 1 and 2 were defined as early-stage PD. Ocular surface disease index (OSDI) questionnaire, tear breakup time (TBUT), Schirmer test, and CIC were applied to the patient and control groups.ResultsThere was no significant difference between the two groups in terms of mean age and gender (p = 0.606, p = 0.357, respectively). Schirmer test and TBUT results in the PD group were significantly lower compared to the control group (p < 0.001, p < 0.001). Meanwhile, the OSDI score and CIC stage of the PD group were significantly higher than that of the control group (p < 0.001, p < 0.001).ConclusionsIn early-stage PD, decreased TBUT and Schirmer test values, conjunctival goblet cell loss, and squamous metaplasia development indicate that the ocular surface is affected. Early diagnosis of dry eye in Parkinson's patients is important for preventing complications such as ocular surface damage and visual disturbances.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251330472"},"PeriodicalIF":1.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing oculoplastic care through telemedicine: AI, opportunities, and challenges. 通过远程医疗推进眼部整形护理：人工智能、机遇和挑战。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-03-18 DOI: 10.1177/11206721251328094

Akshay Gopinathan Nair, Mohammad Javed Ali

引用次数: 0

Assessment of the quality and diagnostic accuracy of patient self-generated photographs used in oculoplastic virtual clinics. 眼整形虚拟诊所中使用的患者自生成照片的质量和诊断准确性评估。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-03-17 DOI: 10.1177/11206721251325276

Gabriella Guevara, Mumta Kanda, Hardeep Kandola, Laxmi Raja, Swan Kang

{"title":"Assessment of the quality and diagnostic accuracy of patient self-generated photographs used in oculoplastic virtual clinics.","authors":"Gabriella Guevara, Mumta Kanda, Hardeep Kandola, Laxmi Raja, Swan Kang","doi":"10.1177/11206721251325276","DOIUrl":"https://doi.org/10.1177/11206721251325276","url":null,"abstract":"BackgroundA barrier to video consultation in oculoplastics is visualising pathology too small for video resolution. Patient self-generated photographs, which is well-documented in teledermatology but not in oculoplastics, may provide a solution.PurposeTo assess the quality and diagnostic accuracy of patient self-generated photographs of presumed benign eyelid pathology.Methods300 patients with suspected benign lid lesions emailed self-captured photographs that were reviewed by two independent reviewers for quality, focussing, and lighting. The photographs were used in a virtual clinic alongside video consultation. Accuracy of virtual clinic diagnosis was measured by comparison to biopsy or in-person diagnosis where available.Results895 photographs were submitted. 84.5% of these were graded as excellent or adequate quality and there was no statistical difference in image quality based on patient age. Concordance between observers for quality of photographs, measured using Cohen's kappa, was k = 0.77 (P = <0.01). Virtual clinic diagnosis was verified in 236 (78.7%) patients by biopsy or in-person review. Correct diagnosis was made in 80.5%. 99.1% of benign lesions were correctly identified as low-risk, 50% of pre-malignant lesions were identified as suspicious, and 100% of malignant lesions were correctly identified as cancerous.ConclusionsPatients of all ages can provide adequate quality photographs that can aid video consultations for benign lid lesions. We still recommend in-person review where suspicious features are present, or photo quality is suboptimal.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251325276"},"PeriodicalIF":1.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of clinical outcomes and vault between two types of posterior phakic intraocular lenses in correction of myopia and myopic astigmatism. 两种后晶状体人工晶状体矫正近视和近视散光的临床疗效比较。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-03-16 DOI: 10.1177/11206721251323642

Alexandre Chingan, Adil El Maftouhi, M Gobeaut, Pauline El Kaim, Christophe Baudouin, Liem Trinh

{"title":"Comparison of clinical outcomes and vault between two types of posterior phakic intraocular lenses in correction of myopia and myopic astigmatism.","authors":"Alexandre Chingan, Adil El Maftouhi, M Gobeaut, Pauline El Kaim, Christophe Baudouin, Liem Trinh","doi":"10.1177/11206721251323642","DOIUrl":"https://doi.org/10.1177/11206721251323642","url":null,"abstract":"PurposeTo compare refractive and clinical outcomes of two posterior chamber phakic intraocular lenses (pIOLs) for correction of myopia and myopic astigmatism. To evaluate the vault and its variance for the phakic lenses by anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM).SettingQuinze-Vingts National Ophthalmology Hospital, Paris, France.Designretrospective case seriesMethodsPatients received an Implantable Collamer Lens (V5 EVO + ICL, Staar surgical AG, Switzerland) or Intraocular Phakic Contact Lens (V2.0 IPCL Caregroup Sight Solution, India). AS-OCT, optical biometry and corneal topography were performed to measure biometric parameters and evaluate post-operative vault.Results12 eyes received an ICL and 14 eyes an IPCL. At 12 months postoperatively, the mean UDVAs were 0.06 ± 0.18 logMAR and 0.16 ± 0.23 logMAR in the ICL and IPCL groups, respectively (p = 0.30). No eye lost CDVA in either group. By AS-OCT, the mean vault was 335.33 ± 165.83 μm and 532.64 ± 167.25 μm in the ICL and IPCL groups, respectively (p = 0.006). By UBM, the mean vault was 355.6 ± 136.6 μm and 509.3 ± 180.79 μm in the ICL and IPCL groups, respectively (p = 0.041).ConclusionsICL and IPCL offer similar refractive and clinical outcomes. IPCL tends to display a more consistent vault with less variation from one patient to another.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251323642"},"PeriodicalIF":1.4,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Translating the renoprotective effects of SGLT2 inhibitors to the diabetic retina. SGLT2抑制剂对糖尿病视网膜的保护作用。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-03-16 DOI: 10.1177/11206721251327647

Maria S Varughese, Lakshminarayanan Varadhan

引用次数: 0

Correlation between aqueous flare levels and anti-VEGF treatment response in wet age-related macular degeneration. 湿性年龄相关性黄斑变性患者水耀斑水平与抗vegf治疗反应的相关性。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-03-16 DOI: 10.1177/11206721251327648

Pinja Sutinen, Sohee Jeon, Piotr Kanclerz, Raimo Tuuminen

{"title":"Correlation between aqueous flare levels and anti-VEGF treatment response in wet age-related macular degeneration.","authors":"Pinja Sutinen, Sohee Jeon, Piotr Kanclerz, Raimo Tuuminen","doi":"10.1177/11206721251327648","DOIUrl":"https://doi.org/10.1177/11206721251327648","url":null,"abstract":"PurposeTo analyze the association between aqueous flare and wet age-related macular degeneration (AMD) activity during anti-VEGF treatment using the treat-and-extend (T&E) protocol.MethodsA single-centre study consisting of 84 eyes of 84 patients with wet AMD and 17 eyes of 17 patients with dry AMD at Ophthalmology Unit, Mehiläinen Hospital, Helsinki, Finland. Aqueous flare levels were recorded with a laser flare meter. Inclusion criteria was a minimum of six anti-VEGF doses given before enrollment to the study.ResultsAqueous flare levels inversely correlated with the anti-VEGF treatment interval (R2 = 0.16, P < 0.001). In the group with a 4-6-week treatment interval the aqueous flare was 13.6 ± 8.3 photon units (pu)/ms compared to 7.9 ± 2.9 pu/ms (P = 0.008), 7.8 ± 3.5 pu/ms (P = 0.006), and 7.2 ± 3.8 pu/ms (P = 0.002) among patients with 7-9-week, 10-12-week, and 13-16-week intervals, respectively. Aqueous flare was 15.4 ± 8.5 pu/ms in the group whose treatment intervals were shortened, compared to 8.6 ± 3.8 pu/ms (P = 0.003) and 7.3 ± 3.3 pu/ms (P < 0.001) in the groups where the treatment intervals were maintained or extended, respectively. Furthermore, aqueous flare levels correlated with the macular volume (R2 = 0.07, P = 0.018). Regarding macular activity, the presence of intraretinal fluid associated with higher aqueous flare levels (13.8 ± 8.6 pu/ms) compared to those without it (8.0 ± 4.0 pu/ms; P < 0.001). Patient age, pseudophakia or the anti-VEGF agent did not associate with the aqueous flare levels.ConclusionsAqueous flare measurements correlated with wet AMD activity during anti-VEGF treatment. Aqueous flare could be used to help evaluate the state of wet AMD patients and assist in decisions regarding anti-VEGF treatment modifications.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251327648"},"PeriodicalIF":1.4,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of CD15 in the bulbar conjunctiva among T2DM patients with ocular surface damage. T2DM伴眼表损伤患者球结膜中CD15的表达。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-03-16 DOI: 10.1177/11206721251327642

Tetiana Zhmud, Stefano Barabino, Galyna Drozhzhyna

{"title":"Expression of CD15 in the bulbar conjunctiva among T2DM patients with ocular surface damage.","authors":"Tetiana Zhmud, Stefano Barabino, Galyna Drozhzhyna","doi":"10.1177/11206721251327642","DOIUrl":"https://doi.org/10.1177/11206721251327642","url":null,"abstract":"BackgroundType 2 diabetes mellitus (T2DM) is a chronic metabolic disorder, which induces ocular surface damage due to low-grade inflammation.AimTo detect and evaluate relative epithelial expression of CD15 in bulbar conjunctiva among patients with and without T2DM based on results of conjunctival impression cytology (CIC), in order to study its role in conjunctival parainflammation related to T2DM.Materials and methodsWe conducted a prospective observational study from March 2023 to December 2023. Forty-eight T2DM patients (96 eyes) were enrolled into a study group. The control group included forty (80 eyes) age- and sex-matched healthy volunteers. All patients underwent conjunctival impression cytology (CIC) and expression of CD15 in bulbar conjunctiva.ResultsExpression of CD15 was detected on epithelial cells in 95% of samples in the study group and 15% of the controls, is statistically significant (p = 0.0000). Mean expression of CD was at 0.96 ± 1.28%, and it was significantly different from the study group with the same Nelson's grade - 3.81 ± 1.48% (p = 0.0351). CD 15 values were significantly higher between Nelson II and III in the study group (3.81 ± 1.48; 7.72 ± 1.65; p = 0.0000, respectively).ConclusionsThe research shows that T2DM patients are prone to increased epithelial expression of CD 15 compared to healthy controls. Relative expression of CD15 may be utilized as a potential marker to evaluate topical treatment outcomes of ocular surface damage in T2DM.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251327642"},"PeriodicalIF":1.4,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Roth spots revealing pernicious anemia in a diabetic patient. 罗斯斑点显示糖尿病患者的恶性贫血。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-03-16 DOI: 10.1177/11206721251323306

Victoria Marechal, Francesca Amoroso, Mathilde M Goudot, Rania Lakraa, Eric Souied

{"title":"Roth spots revealing pernicious anemia in a diabetic patient.","authors":"Victoria Marechal, Francesca Amoroso, Mathilde M Goudot, Rania Lakraa, Eric Souied","doi":"10.1177/11206721251323306","DOIUrl":"https://doi.org/10.1177/11206721251323306","url":null,"abstract":"PurposeTo report a case of pernicious anemia in a patient presenting with white-centered hemorrhages.MethodCase report.ResultsA 64-year-old man with uncontrolled hypertension, insulin-dependent type 2 diabetes, dyslipidemia, and diabetic retinopathy presented with significant bilateral visual acuity reduction. Ophthalmological examination revealed severe diabetic maculopathy, multiple peripapillary Roth spots and hemorrhages. Laboratory tests identified macrocytic anemia with severe vitamin B12 deficiency and an endoscopic biopsy of the gastric fundus led to the diagnosis of pernicious anemia. The patient received blood transfusion, vitamin B12 supplementation and underwent intravitreal anti-VEGF (aflibercept) injections and retinal panphotocoagulation. Over two months, the patient exhibited marked improvement in visual acuity and partial resolution of retinal abnormalities.ConclusionRoth spots are a nonspecific sign that can be found in various pathologies, sometimes severe, such as pernicious anemia. In those cases, adequate vitamin B12 supplementation can resolve the signs and symptoms. Therefore, it is vital to carry out a comprehensive systemic etiological work-up to quickly treat the underlying cause, keeping in mind that multiple pathologies may coexist.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721251323306"},"PeriodicalIF":1.4,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The novel triangular suture technique for intraocular Lens fixation in patients with pseudoexfoliation syndrome suffering from dislocation: Case series. 新型三角缝线技术用于脱位性假脱落综合征患者的人工晶状体固定：病例系列。

IF 1.4 4区医学

European Journal of Ophthalmology Pub Date : 2025-03-13 DOI: 10.1177/11206721241310468

Nir Erdinest, Yossi Eshel, Ori Saban, Edward Averbukh, Samer Khateb, Itay Lavy

{"title":"The novel triangular suture technique for intraocular Lens fixation in patients with pseudoexfoliation syndrome suffering from dislocation: Case series.","authors":"Nir Erdinest, Yossi Eshel, Ori Saban, Edward Averbukh, Samer Khateb, Itay Lavy","doi":"10.1177/11206721241310468","DOIUrl":"https://doi.org/10.1177/11206721241310468","url":null,"abstract":"IntroductionThe current case series presents the triangular suture technique (TST) for managing intraocular lens (IOL) subluxation in pseudoexfoliation (PXF) syndrome patients, a condition increasing the risk of IOL dislocation post-cataract surgery. The series includes three PXF patients treated with TST for dislocated IOLs.Case descriptionThe first case is an 88-years old woman with recurrent IOL dislocation post-Hoffman pocket fixation. TST resulted in successful IOL centration and significant visual acuity improvement, with uncorrected visual acuity (UCVA) improving from 6/60 to 6/15 and best-corrected visual acuity (BCVA) reaching 6/7.5 at three months. The surgery took 21 min with no major complications. The second case involves a 90-year-old man with posterior IOL dislocation and poor vision (UCVA of counting fingers at 1 meter). TST achieved good IOL repositioning and improved BCVA to 6/20 at three weeks. The last case presents an 82 years old woman with PXF and glaucoma, experiencing IOL subluxation post-traumatic cataract surgery. TST successfully centralized the IOL, improving non-corrected visual acuity from 6/30 to 6/10 at six weeks, and BCVA to 6/6.67 at four years. Intraocular pressure remained well-controlled.ConclusionsThis series highlights TST as an effective and safe solution for IOL subluxations in PXF patients, with successful outcomes in all cases. TST offers ease of learning and faster execution, suitable for anterior segment surgeons without extensive vitreoretinal experience. Further studies are needed to confirm the long-term efficacy and safety of TST, ideally involving larger cohorts and longer follow-ups.","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721241310468"},"PeriodicalIF":1.4,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0