European Journal of Ophthalmology最新文献

{"title":"Enhanced visualisation of choroidal osteoma architecture in emboss imaging.","authors":"Udayasree Orugonda, Vaishnavi Patil, Sindhu Nandini Sahoo, Sourabh Prasad Behera, Somy Purohit, Chitaranjan Mishra","doi":"10.1177/11206721261492940","DOIUrl":"https://doi.org/10.1177/11206721261492940","url":null,"abstract":"","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261492940"},"PeriodicalIF":1.3,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149080045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The amalric sign: A clue to giant cell arteritis.","authors":"Federica Lo Cascio, Michele Reibaldi, Enrico Borrelli","doi":"10.1177/11206721261492951","DOIUrl":"https://doi.org/10.1177/11206721261492951","url":null,"abstract":"","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261492951"},"PeriodicalIF":1.3,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149073762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flanged intrascleral fixation for traumatic aphakia and aniridia: A versatile technique for IOL and iris prosthesis implantation.","authors":"Mª Victoria de Rojas Silva, Alejandro López Gaona, Marta Delgado Rodríguez-Vispo, Adrián Tobío Ruibal","doi":"10.1177/11206721261488451","DOIUrl":"https://doi.org/10.1177/11206721261488451","url":null,"abstract":"<p><p>PurposeTo present a versatile surgical technique using flanged polypropylene sutures for intrascleral fixation of both intraocular lenses (IOLs) and iris prostheses (IP) in cases of traumatic aphakia and aniridia, conditions frequently observed following penetrating ocular trauma.MethodsThree cases of post-traumatic aphakia and aniridia were managed using flanged polypropylene suture intrascleral fixation of both the IOL and IP. The technique was adapted to the individual anatomical and clinical complexities of each case.ResultsThis technique provided stable and effective positioning of both the IOL and the IP in all three cases. The adaptability of the method facilitated successful visual and cosmetic rehabilitation, despite the presence of additional ocular structural challenges.ConclusionThe flanged intrascleral fixation technique offers a flexible and effective solution for managing complex cases of aphakia and aniridia following penetrating ocular trauma. Further studies with larger cohorts and longer follow-up are warranted to validate the long-term safety, stability, and visual outcomes of these iris prosthesis implantation techniques.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261488451"},"PeriodicalIF":1.3,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149069608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipoprotein and apolipoprotein levels in age-related macular degeneration: A meta-analysis.","authors":"Vasiliki Arsoudi, Thomas Chontos, Spyridon Voutsas, Petros Petrou, Konstantinos Tyrlis, Ioannis Karavidas, Stylianos A Kandarakis, Stefania Chondrou, Smaragda Diamanti, Constantine D Angelidis, Ilias Georgalas","doi":"10.1177/11206721261492347","DOIUrl":"10.1177/11206721261492347","url":null,"abstract":"<p><p>PurposeDrusen, the hallmark of AMD, are lipoprotein-rich particles. However, the role of systemic lipid metabolism in their formation remains controversial. This meta-analysis explored the association between ApoA1, ApoA2, ApoB and Lp(a) serum levels and AMD.MethodsWe systematically searched MEDLINE, Cochrane Library, EMBASE and Scopus for relevant studies. WMD meta-analyses were performed for ApoA1 and ApoB, whereas SMD meta-analyses were conducted for ApoA2 and Lp(a) serum levels in AMD patients vs healthy controls.ResultsA total of 11 studies with 5,084 subjects for ApoA1, 4,179 for ApoB, 3,177 for ApoA2 and 3,228 for Lp(a) were included. No significant differences were observed between AMD patients (all subtypes) and controls for serum ApoA1 (WMD = 0.29 mg/dL, -3.75 to 4.32, p = 0.89), ApoB (WMD = -2.16 mg/dL, -5.67 to 1.34, p = 0.23), or Lp(a) (g: -0.14, -0.54 to 0.27, p = 0.50). ApoA2 was significantly different (g = 0.2, 0.07 to 0.34, p = 0.003). In severe AMD (geographic atrophy, neovascular AMD), meta-analysis revealed no significant difference for ApoA1 (WMD = -2.68 mg/dL, -8.87 to 3.52, p = 0.4) or ApoB (WMD = -0.42 mg/dL, -6.20 to 5.32, p = 0.89).ConclusionThis meta-analysis discovered no meaningful association between systemic levels of ApoA1, ApoB, or Lp(a) and the presence or severity of AMD. Despite a significant change in ApoA2, utilizing a Reference Change Value based interpretation, we conclude that observed differences in analyzed markers represent physiological and analytical noise rather than true biological change. Our findings suggest that systemic ApoA1, ApoB, and Lp(a) levels are not elevated in individuals with AMD, though the potential role of ApoA2 warrants further investigation.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261492347"},"PeriodicalIF":1.3,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149073770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preferred practice patterns survey of secondary intraocular lens implantation in Spain.","authors":"María Victoria De Rojas Silva, Javier Mendicute, Alfredo García-Layana, Juan Manuel Cubero Parra, Sergio Recalde","doi":"10.1177/11206721261489706","DOIUrl":"https://doi.org/10.1177/11206721261489706","url":null,"abstract":"<p><p>PurposeTo determine preferred practice patterns for secondary intraocular lens (IOL) implantation in the absence of capsular support among Spanish ophthalmologists.MethodsCross-sectional study based on an anonymous online survey conducted in Spain. A 31-item questionnaire was distributed to members of the Spanish Society of Cataract and Refractive Surgery (SECOIR) and the Spanish Retina and Vitreous Society (SERV). It collected data on demographics, preferred surgical techniques, techniques abandoned and reasons for discontinuation, and management of predefined clinical scenarios.ResultsA total of 210 ophthalmologists completed the survey. 29.2% of ophthalmologists younger than 40 years reported no training on this topic during residency. For the management of aphakia without capsular support, 69% preferred delaying secondary IOL placement, mainly to obtain specific instruments or IOLs (83.3%). Complete pars plana vitrectomy was the preferred vitreous management technique (61%). The preferred first-line techniques were retropupillary iris-claw IOL implantation (33.3%), T-shaped harpoon scleral-fixated IOL implantation (28.6%), prepupillary iris-claw IOL implantation (15.2%), and the Canabrava technique (8.6%). Angle-supported anterior chamber IOLs and the Yamane technique were each selected by 3.3% of respondents.ConclusionsRetropupillary iris-claw IOL implantation was the preferred first-line option among Spanish ophthalmologists. Despite improved training among younger surgeons, nearly one third of ophthalmologists under 40 years still reported no formal training, suggesting persistent gaps in residency training.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261489706"},"PeriodicalIF":1.3,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149058804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of knowledge and expectations of blind and visually impaired patients regarding artificial retina.","authors":"Matteo Baldi, Sofia Pischedda, Maria Musolino, Federica Calabria, Michele Iester, Aldo Vagge","doi":"10.1177/11206721261491572","DOIUrl":"https://doi.org/10.1177/11206721261491572","url":null,"abstract":"<p><p>PurposeTo evaluate how blind and visually impaired individuals perceive retinal prosthesis systems and to examine their views regarding potential visual outcomes.MethodsA cross-sectional survey consisting of 12 structured items was distributed through the Italian Union of the Blind and Visually Impaired and regional associations. Adults with visual impairment or blindness completed questions addressing knowledge of \"artificial retina\" technology, information sources, expectations of visual recovery, and awareness of rehabilitation requirements. Descriptive and exploratory subgroup analyses were performed.ResultsNinety-four respondents participated. Although 69% reported some familiarity with \"artificial retina\" technology, only 45% correctly identified its basic functional principle. Most participants obtained information from media and social networks (49%), while 17% reported receiving information from healthcare professionals. Anticipated outcomes frequently exceeded current technological capabilities: 43% anticipated restoration of pre-disease vision and 33% hoped to recognize faces. More limited outcomes, such as light perception, were considered distressing by 57% of respondents. Patterns were broadly similar across diagnostic and demographic subgroups.ConclusionsBlind and visually impaired individuals show strong interest in vision restoration technologies, yet a clinically relevant gap persists between perceived potential and current capabilities. Clear, patient-centered communication and realistic counseling are essential to support informed and realistic understanding while preserving hope.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261491572"},"PeriodicalIF":1.3,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149037338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractive and corneal analyses after custom-Q versus wavefront-optimized ablation in photorefractive keratectomy for myopia.","authors":"Burak Tanriverdi, Nurullah Cagil","doi":"10.1177/11206721261488875","DOIUrl":"https://doi.org/10.1177/11206721261488875","url":null,"abstract":"<p><p>PurposeTo evaluate refractive and tomographical outcomes following Custom-Q without Q-adjustment and wavefront-optimized (WFO) photorefractive keratectomy (PRK) for myopia.MethodsThis retrospective, comparative study included 46 eyes in the Custom-Q group and 40 eyes in the WFO group who underwent PRK for myopia and/or myopic astigmatism. Planned central ablation depth (CAD), total laser pulses (from WaveLight EX500), and corneal thickness (CT) changes at central, paracentral (3.0 mm), and mid-peripheral (6.0 mm) zones (from Sirius tomography) were recorded with visual, refractive, and topographic outcomes preoperatively and at 6 months.ResultsPostoperative sphere was closer to emmetropia in the Custom-Q group (0.041 ± 0.17 D vs. -0.089 ± 0.30 D, p = 0.024), and postoperative flat keratometry was lower than in the WFO group (p = 0.045). For 1.00 D spherical equivalent (SE) correction, Custom-Q resulted in lower planned CAD, less CT change across all zones, and fewer laser pulses than WFO (p < 0.05 for all). Both groups showed comparable safety and efficacy indexes (>1.0), similar significant oblate shift, increased root-mean-square of higher-order aberrations_6mm (RMS-HOAs_6mm), with no significant change in HOAs_3mm (p > 0.05 for all), while spherical aberration_6mm decreased more in the Custom-Q group (-0.080 ± 0.096 vs. -0.040 ± 0.102, p = 0.024, respectively). There was a significant correlation between preoperative SE and changes in asphericity_6mm (r = -0.853, p < 0.001), RMS-HOAs_6mm (r = -0.430, p = 0.008), and spherical aberration_6mm (r = 0.632, p < 0.001) in the Custom-Q group.ConclusionsCustom-Q without Q-adjustment is an effective and safe option for myopic PRK, achieving better refractive precision and lower CT reduction per diopter than WFO, with improved control of spherical aberration despite comparable increases in asphericity and RMS-HOAs_6mm.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261488875"},"PeriodicalIF":1.3,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149037266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of neopterin in rheumatoid arthritis-related dry eye.","authors":"Muzaffer Şahin, Özlem Evren Kemer, Aziz Çardak, Ahmet Omma, Bilge Kilicarslan, Gözde Girgin, Terken Baydar","doi":"10.1177/11206721261491820","DOIUrl":"https://doi.org/10.1177/11206721261491820","url":null,"abstract":"<p><p>PurposeTo compare the relationship between serum and tear neopterin levels of patients diagnosed with rheumatoid arthritis-related dry eye syndrome and evaluate correlation of measured parameters with rheumatoid arthritis activity and dry eye syndrome severity.MethodIn this cross-sectional study, serum and tear levels of neopterin were measured in 57 patients with rheumatoid arthritis and 31 healthy individuals. Participants were divided three groups diagnosed with RA without dry eye (Group 1), or RA having dry eye (Group 2), and healthy controls. OSDI, tear osmolarity, Schirmer I test, and TBUT were evaluated for dry eye. Serum and tear neopterin levels were measured and compared between all groups and healthy controls.ResultsSignificant difference was observed in serum and tear neopterin levels between control and patients, no significant difference was detected between group1 and 2. Comparison of dry eye parameters between groups revealed that Schirmer's I test and TBUT scores were significantly higher, and tear osmolarity and OSDI scores were significantly lower in the control group compared to groups 1,2 (p < 0.001). Statistically low significant correlation was found between tear and serum neopterin levels for all participants (p = 0.003, R_S = 0,316). No significant correlation was found between other parameters of dry eye, RA activity and neopterin level.ConclusionsThe findings of this study indicate that cellular immune activation may not be the only mechanism underlying non-Sjögren's RA-related dry eye. Tear neopterin can be used to indicate the presence of ocular surface disease caused by RA, supporting the presence of extra-articular manifestations.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261491820"},"PeriodicalIF":1.3,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149037286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct selective Laser trabeculoplasty in the management of glaucoma: The first systematic review and meta-analysis.","authors":"Shahad T Ahmad, Rashed A Alasoosi, Ahmed Mohammad, Yaqoub AlFoudari, Sara Almutawtah, Farah R Alqussair, Abdullah Alzoabi, Abdullah AlOtaibi, Fahad Mohammad, Sulaiman D Almusaileem, Abdulrahman Alfailakawi, Abdullah M Alharran","doi":"10.1177/11206721261488444","DOIUrl":"https://doi.org/10.1177/11206721261488444","url":null,"abstract":"<p><p>BackgroundGlaucoma management heavily relies on controlling intraocular pressure (IOP). While selective laser trabeculoplasty (SLT) is a standard first-line therapy, its contact-based approach requires gonioscopy, which demands specialized skills and introduces minor corneal risks. Direct selective laser trabeculoplasty (DSLT) has emerged as an automated, non-contact evolution.MethodsA comprehensive search across five databases was conducted up to March 2026 for randomized controlled trials and non-randomized studies. Primary outcomes were mean absolute IOP reduction and treatment success (>20% IOP reduction). Secondary outcomes included reductions in medication burden and adverse events. Mean differences (MD), risk ratios (RR), and proportions were pooled using a random-effects model.ResultsSeven studies involving 341 patients (446 eyes) were included. In single-arm analyses, DSLT achieved a significant reduction in IOP (Mean Change: -4.35 mmHg, 95% CI [-5.17, -3.53]; <i>p</i> < 0.001) and medication burden (Mean Change: -0.57 drops; <i>p</i> < 0.001), with an overall treatment success rate of 60% (<i>p</i> = 0.001). In pairwise comparisons, DSLT demonstrated comparable efficacy to conventional SLT, with no significant differences in IOP reduction or treatment success. Regarding safety, DSLT showed low rates of severe complications, including corneal changes (1%) and IOP spikes (1%). While transient subconjunctival hemorrhage was frequently associated with translimbal delivery, it was self-limiting.ConclusionDSLT appears to be a promising non-contact procedure, with reductions in IOP and medication use; however, current evidence remains preliminary and largely non-randomized. Also, limited comparative data did not show significant differences compared with SLT. Larger randomized trials are needed before firm clinical recommendations can be made.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261488444"},"PeriodicalIF":1.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149016096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Window within the web: Bilateral florid persistent pupillary membranes.","authors":"Elackiya Manimaran, Eshwar Rajesh, Shanmathi Thiyagarajan","doi":"10.1177/11206721261489699","DOIUrl":"https://doi.org/10.1177/11206721261489699","url":null,"abstract":"<p><p>A 14-year-old boy was found to have bilateral persistent pupillary membranes with best-corrected visual acuity of 6/6 in both eyes. (A, B) Diffuse slit-lamp photographs of the right and left eyes show extensive pigmented pupillary membrane strands arising from the iris collarette and interlacing across the pupillary apertures, producing a dense web-like configuration with multiple irregular fenestrations. (C, D) Retroillumination sharply delineates the membrane architecture against the red reflex, revealing residual optical windows, including clear openings along the visual axis. Despite the florid appearance of the membranes, preservation of these central optical windows likely accounts for the excellent visual acuity. The panels highlight a striking anatomy-function dissociation in which a dense pupillary web retains sufficient optical windows for excellent vision.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261489699"},"PeriodicalIF":1.3,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}