Direct selective laser trabeculoplasty: A retrospective study.

IF 1.4 4区医学 Q3 OPHTHALMOLOGY

European Journal of Ophthalmology Pub Date : 2024-11-25 DOI:10.1177/11206721241301935

Giovanni Fossati, Marco Trevisi, Usman Sarodia, Huzaifa Malick, Hamza Abdou, Modupe Sodeinde, Mario R Romano, Lina Osman

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引用次数: 0

Abstract

Purpose: To investigate the effectiveness and safety profiles of Direct Selective Laser Trabeculoplasty (DSLT).

Materials and methods: Retrospective study of 15 eyes of 10 patients diagnosed with open angle glaucoma (OAG) or ocular hypertension (OHT) who underwent DSLT in June 2023 at University Hospitals of Leicester, UK. We defined success as IOP reduced ≥20% from baseline with no additional medications needed or as a decrease in the number of anti-glaucoma medications while maintaining target IOP. We also considered secondary outcomes such as final BCVA and final number of anti-glaucoma medications.

Results: At the fourth month visit, success was reached in 11 eyes (73.3%). We registered 4 failures (26.7%). Mean IOP at baseline was 22.7 ± 4.4 mmHg and was reduced to 18.7 ± 4.2 mmHg (p = 0.008). The absolute mean reduction of IOP in the group of eyes that maintained unchanged the number of medications was 5.4 ± 2.7 mmHg, as baseline IOP was 21.4 ± 4.3 mmHg, and final IOP was 15.9 ± 2.3 mmHg, with a 25.7% reduction (p = 0.003). Mean BCVA remained unchanged (0.1 ± 0.1 logMAR, p = 1.00). No significant adverse events requiring surgical or clinical intervention were observed.

Conclusion: DSLT showed profiles of effectiveness and safety comparable with those of SLT in the literature and consistent with the results obtained in previous studies on DSLT itself. DSLT may represent a valid alternative to traditional SLT.

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直接选择性激光小梁成形术：回顾性研究

目的：研究直接选择性激光小梁成形术（DSLT）的有效性和安全性：对 2023 年 6 月在英国莱斯特大学医院接受直接选择性激光小梁成形术（DSLT）的 10 名开角型青光眼（OAG）或眼压过高（OHT）患者的 15 只眼睛进行回顾性研究。我们将成功定义为眼压比基线降低≥20%，且无需额外用药，或在维持目标眼压的同时减少了抗青光眼药物的用量。我们还考虑了次要结果，如最终的 BCVA 和最终的抗青光眼药物数量：在第四个月的检查中，有 11 只眼睛（73.3%）获得了成功。我们记录了 4 例失败（26.7%）。基线时的平均眼压为 22.7 ± 4.4 mmHg，后降至 18.7 ± 4.2 mmHg (p = 0.008)。在保持用药次数不变的眼睛组中，眼压绝对平均降低了 5.4 ± 2.7 mmHg，因为基线眼压为 21.4 ± 4.3 mmHg，最终眼压为 15.9 ± 2.3 mmHg，降低了 25.7%（p = 0.003）。BCVA 平均值保持不变（0.1 ± 0.1 logMAR，p = 1.00）。没有观察到需要手术或临床干预的重大不良事件：DSLT显示的有效性和安全性与文献中的SLT相当，也与之前关于DSLT本身的研究结果一致。DSLT 可能是传统 SLT 的有效替代方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Ophthalmology 医学-眼科学

CiteScore

3.60

自引率

0.00%

发文量

372

审稿时长

3-8 weeks

期刊介绍： The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.