European journal of case reports in internal medicine最新文献

{"title":"Schistosomiasis with Pericardial Effusion.","authors":"Elaf Khalid Bajameel, Arifa Jamal, Asem Osama Banjar, Khalid Mohammed Alqahtani, Noura Babikir Ahmed Elsheikh, Arwa Hussain Alkhuraim","doi":"10.12890/2025_005201","DOIUrl":"https://doi.org/10.12890/2025_005201","url":null,"abstract":"<p><p>Schistosomiasis, caused by parasitic flatworms of the genus <i>Schistosoma</i>, is endemic in many areas of the world. We report the case of a young male patient presenting with persistent fever, abdominal pain, vomiting and diarrhoea, with travel history to Al Baha, Saudi Arabia, an endemic area for schistosomiasis. Diagnostic imaging revealed hepatosplenomegaly and pericardial effusion. Despite negative stool and blood cultures, the clinical presentation and travel history supported the diagnosis of schistosomiasis. The patient was started on praziquantel and prednisolone therapy, resulting in significant clinical improvement. A follow-up echocardiogram one month later showed complete resolution of the pericardial effusion.</p><p><strong>Learning points: </strong>Pericardial effusion is a rare complication but should be considered in a patient diagnosed with schistosomiasis who presents with tachycardia, tachypnoea and dyspnoea.Negative stool culture does not rule out the infection in patients with history of travel to an endemic area with high clinical suspicion.Early recognition and management of complications will improve patient outcomes.Praziquantel, with or without steroids, is the standard treatment for managing schistosomiasis and its complications.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005201"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oesophageal Dysmotility in a Patient with Charcot-Marie-Tooth Disease: Report and Literature Review.","authors":"Mohammad Kloub, Abdul-Rahman I Abusalim, Mohamed Eldesouki, Mohammad Abushanab, Byron Okwesili, Raed Atiyat, Yatinder Bains","doi":"10.12890/2025_005219","DOIUrl":"https://doi.org/10.12890/2025_005219","url":null,"abstract":"<p><p>Oesophageal dysmotility is a serious condition characterised by impaired coordination of oesophageal smooth muscle contractions, which can be secondary to a variety of causes including infection, inflammation and malignancy. The presenting symptoms are variable and include chest or epigastric pain, food regurgitation, heartburn or cough, making it difficult to distinguish. Diagnostic modalities and treatment strategies vary depending on the underlying cause. Once oesophageal dysmotility is suspected, a thorough evaluation is essential as the management strategies and prognosis of the condition differ significantly based on the underlying pathology. A multidisciplinary approach and clinical expertise are essential for optimal patient care and treatment. While neuromuscular disorders are associated with swallowing dysfunction due to oropharyngeal muscle involvement, oesophageal smooth muscles involvement is rare. This case highlights the importance of careful and frequent evaluation of both respiratory and gastrointestinal smooth muscle function, particularly in patients with chronic neurological disorders.</p><p><strong>Learning points: </strong>Charcot-Marie-Tooth disease has the potential to involve smooth muscles, including those of the diaphragm and gastrointestinal tract.Regular and detailed evaluation of respiratory and swallowing functions is advised for patients with neurological disorders to monitor for early signs of dysfunction.Aspiration pneumonia should always be in the differential in patients with recurrent pneumonia and warrants thorough evaluation to ensure appropriate diagnosis and management.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005219"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transient Global Amnesia Triggered by Cold Water Swimming: A Series of 9 Cases Presenting to a Hospital on the Coast of Ireland Within 5 Years.","authors":"Colm Tuohy, Ginna Alexandra Polania Zuleta","doi":"10.12890/2025_005200","DOIUrl":"https://doi.org/10.12890/2025_005200","url":null,"abstract":"<p><strong>Background: </strong>Transient global amnesia is a clinical syndrome characterized by sudden onset of anterograde amnesia, often accompanied by repetitive questioning, lasting up to 24 hours with complete resolution and no other neurological deficits. This case series presents 9 patients who experienced transient global amnesia following sea swimming between 2019 and 2024 at Bantry General Hospital, a hospital located in a coastal town on the south of Ireland.</p><p><strong>Case presentations: </strong>Patients who presented with \"amnesia\" or \"transient global amnesia\" were identified through searching the hospital database. Patients whose symptoms were directly related to sea swimming were included in this report. All 9 patients were women, with ages ranging from 55 to 82 years. Symptoms typically developed during or immediately after swimming, with durations ranging from 1 to 7 hours. Common symptoms included confusion, short-term memory loss, repetitive questioning and disorientation to time and/or place. Water temperatures ranged from 9.2°C to 18°C. Neuroimaging, including computed tomography scans of the brain for all patients and magnetic resonance imaging for 3 patients, showed no acute changes. All patients experienced full symptom resolution within 24 hours.</p><p><strong>Conclusions: </strong>This case series highlights the link between cold water immersion during sea swimming and transient global amnesia. The consistent association with sea swimming aligns with previous reports identifying cold water immersion as a trigger for transient global amnesia. These findings warrant further investigation into the relationship between sea swimming and transient global amnesia. Clinicians should be aware of this potential trigger when evaluating patients with acute onset amnesia, especially in coastal areas.</p><p><strong>Learning points: </strong>This case series highlights the link between sea swimming and the occurrence of transient global amnesia.With the increasing popularity of sea swimming around Europe, clinicians should be aware of this phenomenon.Further research is necessary to understand the underlying mechanism behind this phenomenon.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005200"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Budd-Chiari Syndrome as the Presenting Feature of Systemic Immunoglobulin Light Chain Amyloidosis.","authors":"João Luís Miranda, Catarina Salvado, Francisca Carmo, Adriana Guedes, Albina Moreira, Tiago Guimarães Costa, Leonor Silva","doi":"10.12890/2025_005153","DOIUrl":"https://doi.org/10.12890/2025_005153","url":null,"abstract":"<p><p>Budd-Chiari syndrome (BCS), characterised by hepatic venous outflow obstruction, is frequently associated with hypercoagulable states. Systemic immunoglobulin light chain (AL) amyloidosis, on the other hand, commonly presents with bleeding complications. The association between the two diseases is not common, but some cases have been described in the past. We report a case of a 58-year-old male who presented with lower limb oedema, abdominal distention and severe fatigue, ultimately diagnosed with BCS secondary to systemic AL amyloidosis. This case highlights the rare association between AL amyloidosis and BCS, likely precipitated by a nephrotic syndrome-induced hypercoagulable state, and emphasises the need for clinicians to consider systemic amyloidosis when investigating the aetiology of BCS, even in the absence of typical bleeding manifestations.</p><p><strong>Learning points: </strong>AL amyloidosis is typically associated with bleeding disorders, but rarely can present with thrombotic complications as well, specifically when associated with nephrotic syndrome.Budd-Chiari syndrome is a life-threatening condition which should be on the differential diagnosis of subacute liver failure.A thorough aetiological investigation is essential in a patient with Budd-Chiari syndrome, including consideration for potential causes of nephrotic syndrome and other less typical disease associations.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005153"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clevidipine Induced Intrapulmonary Shunting in a Patient with Acute Type B Aortic Dissection.","authors":"Mit Chauhan, Masara Touza, John Paul Fox, Asma Jamil, Ruhma Ali, Alan Klukowicz, Nirav Mistry","doi":"10.12890/2025_005095","DOIUrl":"https://doi.org/10.12890/2025_005095","url":null,"abstract":"<p><p>Clevidipine is a short acting calcium channel blocker commonly used to treat uncontrolled hypertension. The common side-effects include depression, dizziness, and headache. Hypoxia from intrapulmonary shunting after clevidipine use has not been widely reported in the literature. We present a case of acute type B aortic dissection treated with esmolol and clevidipine complicated by hypoxia which resolved post discontinuation of clevidipine.</p><p><strong>Learning points: </strong>Clevidipine may be used as an adjunct to beta blockers if the patient is still hypertensive or beta blockers are contraindicated.Intrapulmonary shunting leading to hypoxia is a rare complication of clevidipine therapy and should be suspected in an otherwise hypoxic patient in whom all other diagnoses have been ruled out.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005095"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reversible Thyrotoxicosis Caused by Suppurative Thyroiditis in a Young Healthy Woman.","authors":"Begüm Süeda Sert, Roderick F A Tummers-de Lind van Wijngaarden, Jacqueline Buijs","doi":"10.12890/2025_005101","DOIUrl":"https://doi.org/10.12890/2025_005101","url":null,"abstract":"<p><strong>Introduction: </strong>Acute suppurative thyroiditis is a bacterial infection of the thyroid gland. Potential risk factors are an immunocompromised state or the presence of pre-existing thyroid disease. Acute suppurative thyroiditis may be complicated by abscess formation and/or thyrotoxicosis, which are both rare but potentially life-threatening complications.</p><p><strong>Case description: </strong>We describe a case of acute suppurative thyroiditis secondary to tonsillitis in a 22-year-old healthy female presenting with thyrotoxicosis due to abscess formation. She presented with complaints of palpitations, fever, extreme salivation, dysphagia, pain and swelling of the neck. Further analysis revealed a sinus tachycardia, high inflammatory parameters, and clinical and biochemical signs of thyrotoxicosis. Computed tomography showed abscess formation in the left lobe of the thyroid gland with extension to the retropharyngeal space and deviation of the trachea to the contralateral side. Blood cultures were positive for <i>Streptococcus constellatus</i> and <i>Prevotella intermedia</i>. The patient was treated with antibiotics and underwent an operative excision and drainage of the abscess and recovered well. Symptomatic thyrotoxicosis was treated with metoprolol. <i>P. intermedia</i> has not previously been implicated in causing acute bacterial thyroiditis.</p><p><strong>Conclusion: </strong>Acute suppurative thyroiditis may occur in healthy young adults without any predisposing factors. Concomitant thyrotoxicosis is rare, but important to diagnose. Bacterial thyroiditis may be either a primary thyroid infection or a secondary complication of a severe tonsillitis. Early recognition and treatment are of great importance to reduce overall mortality and morbidity, and to prevent the development of complications.</p><p><strong>Learning points: </strong>Suppurative thyroiditis can lead to overt but potentially reversible thyrotoxicosis.Bacterial thyroiditis can occur in healthy young adults, although immune compromised patients and patients with anatomical variants are more susceptible.Acute suppurative thyroiditis is usually associated with a euthyroid state.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005101"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Bowel Perforation Post-Bowel Preparation in a Patient with Connective Tissue Disease.","authors":"Omar Brijawi, Spencer Jude, Evan Hartman, Richard Fox, Alex Kemei, Matthew Chakan","doi":"10.12890/2025_005248","DOIUrl":"https://doi.org/10.12890/2025_005248","url":null,"abstract":"<p><p>Isosmotic oral agents are commonly used in bowel preparation due to their minimal side effects. However, bowel perforation is a rare and severe complication. Connective tissue disease and medications such as nonsteroidal anti-inflammatory drugs/steroids can weaken the colonic wall, which increases the risk of perforation. We present a case of a 67-year-old male with undifferentiated mixed connective tissue disease who developed a bowel perforation after administration of bowel prep. The patient initially presented to the emergency department with diffuse abdominal pain, with imaging showing evidence of perforation. Despite surgical and medical intervention, the patient passed away.</p><p><strong>Learning points: </strong>This case highlights that oral isosmotic agents that are commonly used for bowel preparation are not risk free.This case highlights that patients with connective tissue disease who receive bowel preparation with oral isosmotic agents are at increased risk for adverse events.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005248"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Hypomagnesemia Induced by Postoperative Zinc Supplementation: An Illustrative Demonstration of Electrolyte Homeostasis.","authors":"Max Slosarski, Christ Ordookhanian, Ryan F Amidon, Edward Lee, Tedrik Markarian, Paul Kaloostian","doi":"10.12890/2025_005247","DOIUrl":"https://doi.org/10.12890/2025_005247","url":null,"abstract":"<p><strong>Background: </strong>Managing electrolyte abnormalities is one of the cornerstones of properly caring for and managing hospitalized patients. Typically, electrolyte derangements are managed by direct repletion, volume status correction, or hemodialysis; however, the persistence of electrolyte abnormalities despite utilizing appropriate initial strategies requires further investigation.</p><p><strong>Case description: </strong>A 72-year-old male presented to the emergency department with weakness 2 months post-exploratory laparotomy with ileostomy for small bowel perforation complicated by intra-abdominal infection. The patient was treated for sepsis and imaging revealed intra-abdominal and abdominal wall abscesses. After drainage, recovery was complicated by treatment of refractory hypomagnesemia in the context of zinc supplementation.</p><p><strong>Discussion: </strong>If initial electrolyte repletion measures do not provide the intended benefit, investigating secondary causes of refractory electrolyte abnormalities is necessary. While hypomagnesemia is one of the least common electrolyte derangements seen within the general acute care hospital setting, in facilities with relatively high volumes of bariatric or gastrointestinal surgical patients, keeping the phenomenon of zinc-induced hypomagnesemia in mind becomes more crucial due to its frequent use in those settings.</p><p><strong>Conclusion: </strong>This case highlights the effects of excess high-dose zinc supplementation in a patient without zinc deficiency in the postoperative period who developed treatment-resistant hypomagnesemia due to zinc-induced impairment of magnesium absorption as well as gastrointestinal and renal losses.</p><p><strong>Learning points: </strong>Zinc supplementation can cause hypomagnesemia.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005247"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traumatic Axonal Injury Successfully Treated with Secretome Followed by Mesenchymal Stem Cells Therapy.","authors":"Ahmad Faried, Yeremia Tatang, Gibran A Wibawa, Wahyu Widowati, Anindita P Distya","doi":"10.12890/2025_005111","DOIUrl":"https://doi.org/10.12890/2025_005111","url":null,"abstract":"<p><strong>Introduction: </strong>Traumatic axonal injury (TAI), a head injury condition formerly known as diffuse axonal injury, results from direct mechanical forces causing multiple scattered lesions, either haemorrhagic or non-haemorrhagic, within brain tissue. Despite its clinical significance, no prior research has explored the use of stem cells in a TAI inpatient setting. This case presents the efficacy of stem cell therapy for TAI.</p><p><strong>Case description: </strong>A 17-year-old boy sustained severe head injuries from repeated blows, resulting in a coma. Initial CT and MRI scans showed cerebral oedema without haemorrhagic lesions. T2-weighted axial FLAIR imaging showed two hyperintensity lesions in the corpus callosum, consistent with diffuse axonal injury grade II. Secretome and umbilical cord mesenchymal stem cell (UCMSC) therapy were administered. The patient showed improvement in motor function and speaking and was discharged without neurological deficits.</p><p><strong>Discussion: </strong>The pathophysiology of TAI remains unclear because of a lack of unifying theory. It is theorised that not only is direct mechanical injury the cause of primary damage but biochemical changes in neuronal metabolism also play a role as secondary damage. Two main therapeutic options can be recognised. Treatment approaches fall into two categories: secondary axotomy-targeted therapy and promotion of neural regeneration. Multiple treatment options promote both microenvironment correction and neuronal regeneration, including cell and stem cell therapy along with its metabolite.</p><p><strong>Conclusion: </strong>Stem cell therapy is promising as an alternative treatment modality in a case where there was no other optional therapy for TAI.</p><p><strong>Learning points: </strong>A traumatic axonal head injury (TAI) patient in a coma for one month responded within four days of secretome therapy and further improved and became fully alert four days after mesenchymal stem cell treatment.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005111"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metachronous Occurrence of Acute Myeloid Leukaemia in a Case of Neuroendocrine Tumour.","authors":"Abhinav Menon, Dilip Harindran Vallathol, Deepak Charles, Shagos Nair, Karthika Kundil Veetil, Ashok S Komaranchath, Arun R Warrier","doi":"10.12890/2025_005233","DOIUrl":"https://doi.org/10.12890/2025_005233","url":null,"abstract":"<p><p>Haematological neoplasms are rare in patients undergoing peptide receptor radionuclide therapy (PRRT) for neuroendocrine neoplasms, though the long-term effects on bone marrow function remain an area of interest. We report the case of an elderly woman diagnosed with a pancreatic neuroendocrine tumour (pNET) who developed acute myeloid leukaemia (AML) while receiving PRRT. She was treated with a non-chemotherapy regimen of azacitidine and venetoclax, resulting in remission of both AML and the neuroendocrine tumour. This case highlights the potential risk of secondary haematological malignancies following PRRT and underscores the efficacy of a non-intensive therapeutic approach in managing AML in this context.</p><p><strong>Learning points: </strong>This case highlights the sequential use of peptide receptor radionuclide therapy (PRRT) with octreotide in managing a metastatic neuroendocrine tumour (NET) and its transition to a chemotherapy-free regimen for secondary acute myeloid leukaemia (AML). The integration of targeted radionuclide therapy with molecular oncology approaches is an evolving treatment paradigm that can modify future medical practice.The case underscores the challenge of detecting therapy-related myeloid neoplasms in patients undergoing PRRT. The delayed diagnosis of AML due to pancytopenia highlights the need for vigilant haematologic monitoring in patients receiving long-term PRRT and somatostatin analogue therapy.The successful management of both malignancies showcases the importance of multidisciplinary tumour boards in decision-making. It emphasises the role of internists in coordinating oncology care, recognising complications and implementing individualised treatment strategies to improve patient outcomes.</p>","PeriodicalId":11908,"journal":{"name":"European journal of case reports in internal medicine","volume":"12 4","pages":"005233"},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}