Environmental Health Perspectives最新文献

{"title":"Erratum: \"Determinants of PFOA serum half-life after end of exposure: a longitudinal study on highly exposed subjects in the Veneto Region\".","authors":"Erich Batzella, Isabella Rosato, Gisella Pitter, Filippo Da Re, Francesca Russo, Cristina Canova, Tony Fletcher","doi":"10.1289/EHP17398","DOIUrl":"https://doi.org/10.1289/EHP17398","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to \"Comment on 'Exposure to Per- and Polyfluoroalkyl Substances and Mortality in U.S. Adults: A Population-Based Cohort Study'\".","authors":"Xue Wen, Mei Wang, Xuewen Xu, Tao Li","doi":"10.1289/EHP17324","DOIUrl":"10.1289/EHP17324","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to \"Comment on 'Occupational Benzene Exposure and Lung Cancer in Human Studies: A Systematic Review and Meta-Analysis'\".","authors":"Wenxin Wan, Susan Peters, Lützen Portengen, Ronnie Babigumira, Jo Steinson Stenehjem, David Richardson, Roel Vermeulen","doi":"10.1289/EHP17293","DOIUrl":"https://doi.org/10.1289/EHP17293","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Occupational Benzene Exposure and Lung Cancer in Human Studies: A Systematic Review and Meta-Analysis\".","authors":"Jian Huang","doi":"10.1289/EHP17036","DOIUrl":"https://doi.org/10.1289/EHP17036","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Asking Why Is Necessary to Address Health Disparities: A Critical Approach for Solution-Oriented Environmental Epidemiological Research\".","authors":"Alvaro J Idrovo","doi":"10.1289/EHP16851","DOIUrl":"https://doi.org/10.1289/EHP16851","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invited Perspective: Should You Scrap Your Plastic Cutting Board?","authors":"Eliseo F Castillo, Katrina Smith Korfmacher, Anna Christina Tyler","doi":"10.1289/EHP17049","DOIUrl":"https://doi.org/10.1289/EHP17049","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A prospective ultrasound study of whole blood metals and incidence of uterine leiomyomata.","authors":"Ruth Geller, Amelia K Wesselink, Birgit Claus Henn, Kristen Upson, Marco Vinceti, Quaker E Harmon, Donna D Baird, Ganesa Wegienka, Lauren A Wise","doi":"10.1289/EHP15218","DOIUrl":"https://doi.org/10.1289/EHP15218","url":null,"abstract":"<p><strong>Background: </strong>Uterine leiomyomata (UL), hormone-dependent neoplasms, are a major source of gynecologic morbidity. Metals are hypothesized to influence UL risk through endocrine disruption, and their effects may vary by vitamin D status.</p><p><strong>Objective: </strong>We estimated associations of a metal mixture with incident UL, overall and by vitamin D status.</p><p><strong>Methods: </strong>We analyzed data from the Study of Environment, Lifestyle and Fibroids, a Detroit-area prospective cohort study of 1,693 Black women aged 23-35 years. We measured concentrations of 17 metals/metalloids in whole blood and 25-hydroxyvitamin D (25[OH]D) in serum collected at baseline (2010-2012). Participants underwent ultrasonography at baseline and after 20 months to detect UL. We used Bayesian Kernel Machine Regression to estimate adjusted associations (β) of the metal mixture with probit of incident UL. We also ran Cox regression models with interaction terms to estimate incidence rate ratios (IRR) by vitamin D status.</p><p><strong>Results: </strong>Among 1,132 UL-free participants at baseline, 832 (73%) had vitamin D deficiency (25[OH]D<20 ng/mL) and 117 (10%) developed UL within 20 months. Increasing all metals from their 50^th to 75^th percentiles was weakly positively associated with UL overall (β=0.06, 95% credible interval [CrI]: -0.03, 0.16) and among vitamin D-deficient participants (β=0.13, 95% CrI: 0.01, 0.24), driven by cadmium (overall and vitamin D-deficient) and mercury (vitamin D-deficient only). Increasing cadmium from its 25^th to 75^th percentile was positively associated with UL overall (β=0.03, 95% CrI: -0.05, 0.11) and among vitamin D-deficient participants (β=0.13, 95% CrI: 0.02, 0.24). In Cox models, cadmium (IRR=1.55, 95% confidence interval [CI]: 1.07, 2.24, per 1-unit increase in standardized concentration) and mercury (IRR=1.38, 95% CI: 0.99, 1.92) were positively associated with UL among vitamin D-deficient participants.</p><p><strong>Discussion: </strong>The metal mixture was positively associated with incident UL, but the association was weak and imprecise. We observed a stronger association among vitamin D-deficient participants that was driven by cadmium and mercury. https://doi.org/10.1289/EHP15218.</p>","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invited Perspective: Prenatal and childhood exposure to fluoride and cognitive development: findings from the longitudinal MINIMat cohort in rural Bangladesh.","authors":"Christine Till","doi":"10.1289/EHP16269","DOIUrl":"https://doi.org/10.1289/EHP16269","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimating the effects of hypothetical ambient PM_2.5 interventions on the risk of dementia using the parametric g-formula in the UK Biobank cohort.","authors":"Chengyi Lin, Riyang Liu, Caroline Sutton, Andrew Thomas DeWan, Laura Forastiere, Kai Chen","doi":"10.1289/EHP14723","DOIUrl":"https://doi.org/10.1289/EHP14723","url":null,"abstract":"<p><strong>Background: </strong>Emerging evidence identifies ambient particulate matter with an aerodynamic diameter ≤ 2.5μm (PM_2.5) as a modifiable risk factor for dementia, but the potential health benefits gained by enacting regulations that reduce PM_2.5 remain unclear.</p><p><strong>Objectives: </strong>Our aim was to estimate the total effects of hypothetical ambient PM_2.5 interventions starting in late life on the risk of dementia in a cohort using the parametric g-formula.</p><p><strong>Methods: </strong>We used data from 291,495 participants in the UK Biobank cohort who were free of dementia and aged ≥ 55 years at baseline (2010). We estimated the total effects of hypothetical ambient PM_2.5 interventions (achieving annual average standards of 12 μg/m³, 10 μg/m³, and 9 μg/m³) from 2010 to 2019 on the risk of dementia by calculating the difference between the estimated 10-year risk of dementia under a specified hypothetical intervention and the risk under no intervention using the parametric g-formula.</p><p><strong>Results: </strong>Compared with no intervention, the estimated 10-year risk difference of dementia was -0.54 per 1000 population (95%CI: -1.00, -0.10), -1.36 per 1000 population (95%CI: -2.44, -0.25), -1.92 per 1000 population (95%CI: -3.39, -0.33), with PM_2.5 interventions achieving annual average standards of 12 μg/m³, 10 μg/m³, and 9 μg/m³, respectively.</p><p><strong>Discussion: </strong>The estimated 10-year risk of dementia decreased if the individual ambient PM_2.5 exposure was reduced due to more stringent PM_2.5 standards in late life compared to the natural course without intervention on ambient PM_2.5 exposure. Our findings, obtained using the parametric g-formula - a causal inference method that can directly evaluate the impact of hypothetical interventions - suggest that policies reducing ambient PM_2.5 pollution may lower the risk of dementia among UK Biobank participants who would experience more stringent ambient PM_2.5 standards in late life. https://doi.org/10.1289/EHP14723.</p>","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invited Perspective: Toward Making Environmental Epidemiology Research More Impactful in Policy-Relevant Risk Assessments.","authors":"Anneclaire J De Roos","doi":"10.1289/EHP16725","DOIUrl":"https://doi.org/10.1289/EHP16725","url":null,"abstract":"","PeriodicalId":11862,"journal":{"name":"Environmental Health Perspectives","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143575563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}