Endoscopy International Open最新文献

{"title":"Response to comment on \"Endoscopic submucosal dissection for proximal colonic lesions: an effective therapeutic option\".","authors":"Ludovico Alfarone, Cesare Hassan, Alessandro Repici","doi":"10.1055/a-2543-1552","DOIUrl":"https://doi.org/10.1055/a-2543-1552","url":null,"abstract":"","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a25431552"},"PeriodicalIF":2.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PuraStat for gastrointestinal bleeding management: Effective approach for endoscopic prevention and rescue therapy.","authors":"Elettra Merola, Giovanni Mario Pes, Maria Pina Dore","doi":"10.1055/a-2550-6600","DOIUrl":"https://doi.org/10.1055/a-2550-6600","url":null,"abstract":"","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a25506600"},"PeriodicalIF":2.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coagulation, clipping and closure method: New combined approach to prevent delayed bleeding after gastric endoscopic submucosal dissection.","authors":"Satoshi Abiko, Haruhiro Inoue, Kei Ushikubo, Kazuki Yamamoto, Yohei Nishikawa, Ippei Tanaka, Naoya Sakamoto","doi":"10.1055/a-2549-9969","DOIUrl":"https://doi.org/10.1055/a-2549-9969","url":null,"abstract":"","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a25499969"},"PeriodicalIF":2.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11998632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in colonoscopy performance among four endoscopy centers in Western Norway: Influence of case-mix.","authors":"Tom Andre Pedersen, Trond Engjom, Georg Gjorgji Dimcevski, Edoardo Botteri, Birgitte Seip, Roald Flesland Havre","doi":"10.1055/a-2546-9515","DOIUrl":"https://doi.org/10.1055/a-2546-9515","url":null,"abstract":"<p><strong>Background and study aims: </strong>Unmodifiable patient factors such as age, sex, and indication (case-mix) may influence colonoscopy performance. In this study, we explored how case-mix affected polyp detection, cecal intubation, and pain on a center level.</p><p><strong>Methods: </strong>A cross-sectional study was performed on data from four centers in Western Norway registered in the national endoscopy quality registry, Gastronet, in 2020 and 2021. We extracted demographics, indication, and the performance measures cecal intubation rate (CIR), proportion of at least one polyp ≥ 5 mm in size per colonoscopy (PDR-5), and pain. We also analyzed the explanatory variables bowel preparation, withdrawal time, and sedation/analgesia.</p><p><strong>Results: </strong>First colonoscopies in 14,765 patients were included. Median age was 60 years (interquartile range 46-71) and 54% were women. Case-mix differed between centers and significantly influenced performance measures. Increased PDR-5 was associated with higher age and male sex (odds ratio [OR] 1.27, 95% confidence interval [CI] 1.18-1.37). The indication surveillance had the highest PDR-5 (44.9%, 95% CI 42.6-47.1) and inflammatory bowel disease the lowest (14.6%, 95% CI 12.3-16.8). CIR decreased with increasing age. Men had less pain (OR 0.33, 95% CI 0.27-0.39). Among indications, surveillance and IBD had higher CIRs and less pain. Performance measures differed among centers, even after adjustment for case-mix and other known explanatory variables such as sedation/analgesia and bowel preparation.</p><p><strong>Conclusions: </strong>Case-mix influenced performance measures. Although we showed center differences in performance, other factors, such as individual endoscopist skills, probably influence performance measures. Our study demonstrates the importance of considering case-mix when assessing colonoscopy performance.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a25469515"},"PeriodicalIF":2.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early cholangioscopy-guided lithotripsy for clearance of biliary stones associated with narrow lower bile duct.","authors":"Pankaj Gupta, Vikas Singla, Pankaj Singh, Kaushal Madan, Shivam Kaalia, Muzaffer Rashid Shawl, Akash Goel, Pallavi Garg, Richa Bhargava","doi":"10.1055/a-2552-4629","DOIUrl":"https://doi.org/10.1055/a-2552-4629","url":null,"abstract":"<p><strong>Background and study aims: </strong>Stones larger than the distal common bile duct (CBD) are difficult to remove with conventional techniques. Large papillary balloon dilatation (> 12 mm) of the biliary sphincter is an effective technique for stone removal but is associated with risk of leak in patients with narrower lower CBD. Mechanical or cholangioscopy-guided lithotripsy has been used in this situation for clearance of the bile duct. In the present study, we report outcomes of early cholangioscopy-guided lithotripsy in patients with narrow lower CBD compared with stone size.</p><p><strong>Patients and methods: </strong>The present study is a retrospective analysis of prospectively collected data from all patients with large proximal stones with a narrow lower bile duct who underwent digital cholangioscopy and electrohydraulic lithotripsy (EHL). Outcomes were proportion of patients with complete bile duct clearance after the first session of electrohydraulic lithotripsy, mean number of EHL sessions for complete clearance, and complications.</p><p><strong>Results: </strong>Eighty-one patients with mean age 54 ± 17 years underwent digital cholangioscopy and EHL. Mean stone size was 14.02 ± 3.5 mm and 71 patients (87.7%) had a stone only in the bile duct. Three (3.7%) and seven patients (8.6%) had stones also in the cystic duct and intrahepatic ducts, respectively. Balloon sphincteroplasty never exceeding distal CBD size was performed in 12 patients (14.8%). Complete stone clearance was achieved in 78 patients (96.3%) after a single session. Mean number of EHL sessions were 1.04 ± 0.19. Three patients developed mild adverse events, which were managed conservatively.</p><p><strong>Conclusions: </strong>Early upfront digital cholangioscopy with EHL has high efficacy and safety for stone clearance after a single session in patients with narrow distal CBD.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a25524629"},"PeriodicalIF":2.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transpapillary biliary drainage using a forward-viewing endoscope for patients with distal malignant biliary obstruction and type I duodenal stenosis.","authors":"Yuichi Hirata, Kazuhiro Iida, Kei Takahashi, Mariko Hatada, Kana Miyara, Yuichiro Aoyama, Ryosuke Mizukami, Takahiro Oribe, Mizuka Yonezawa, Daisuke Orita, Ryutaro Yoshida, Michitaka Kouhashi, Takuya Mimura, Akihiko Nishizawa, Yoshihide Ueda, Kenzo Yamashiro, Yoshihiro Okabe","doi":"10.1055/a-2554-2784","DOIUrl":"https://doi.org/10.1055/a-2554-2784","url":null,"abstract":"<p><strong>Background and study aims: </strong>Distal malignant biliary obstruction and duodenal stenosis may be complicated in patients with pancreaticobiliary cancer. It is often difficult to insert a side-viewing duodenoscope and perform transpapillary biliary drainage in patients with duodenal stenosis on the oral side of the major papilla; hence, in this study, we attempted transpapillary biliary drainage using a forward-viewing endoscope and reported its efficacy and safety.</p><p><strong>Patients and methods: </strong>This retrospective single-center cohort study included 12 patients (17 sessions) who underwent transpapillary biliary drainage using a forward-viewing endoscope between April 2020 and October 2024. The tip of the forward-viewing endoscope was inverted around the inferior duodenal angulus and the major papilla was viewed from the anal side. We evaluated patient characteristics, outcomes, and adverse events (AEs) during these procedures.</p><p><strong>Results: </strong>Biliary cannulation and drainage were successful in all cases, with a median cannulation and procedure time of 7 minutes (range 0.5-34) and 33 minutes (range 10-101), respectively. Median biliary cannulation time required was 3.5 minutes (range 0.5-15) for 10 sessions in patients with a history of endoscopic sphincterotomy and 9 minutes (range 4-34) for seven sessions in patients with native papilla ( <i>P</i> = 0.01). The types of biliary drainage were plastic stent in nine sessions, endoscopic nasobiliary drainage in two sessions, and self-expandable metal stent in six sessions. Hyperamylasemia as AEs occurred in three sessions.</p><p><strong>Conclusions: </strong>Transpapillary biliary drainage using a forward-viewing endoscope is a useful option for patients with type I duodenal stenosis.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a25542784"},"PeriodicalIF":2.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of multi-loop traction device-assisted colorectal endoscopic submucosal dissection: Multicenter randomized clinical trial.","authors":"Mamoru Ito, Yuko Miura, Yasuhiko Mizuguchi, Hiroto Furuhashi, Yosuke Tsuji, Hiroyuki Takamaru, Naoto Tamai, Mitsuhiro Fujishiro, Yutaka Saito, Kazuki Sumiyama","doi":"10.1055/a-2466-0718","DOIUrl":"https://doi.org/10.1055/a-2466-0718","url":null,"abstract":"<p><strong>Background and study aims: </strong>The multi-loop traction device (MLTD) facilitates optimal visualization of the submucosa throughout endoscopic submucosal dissection (ESD). This trial aimed to assess the efficacy of MLTD for colorectal ESD.</p><p><strong>Patients and methods: </strong>We conducted a multicenter, open-label, randomized controlled trial involving patients with colorectal lesions ≥ 20 mm suspicious for noninvasive carcinoma. Participants were randomly assigned in a 1:1 ratio to undergo ESD with MLTD (MLTD-ESD group) or ESD without any traction device (control group). Endoscopists were allowed to convert treatments if dissection became challenging for 10 minutes. The primary endpoint was dissection speed; secondary endpoints included technical success rate and adverse events (AEs).</p><p><strong>Results: </strong>A total of 108 participants were randomized to the MLTD-ESD group (n = 53) and the control group (n = 55). There was no statistically significant difference in median dissection speed between the MLTD-ESD group and the control group (14.8 mm ² /min; interquartile range [IQR] 8.9-23.9 mm ² /min vs. 13.3 mm ² /min; IQR 8.9-18.8 mm ² /min) ( <i>P</i> = 0.33). The technical success rate was significantly higher in the MLTD-ESD group (96.2%) compared with the control group (71.0%) ( <i>P</i> < 0.0001). All technical failures were due to treatment conversions. No significant difference was observed in AEs. Subgroup analysis revealed that experts in the MLTD-ESD group had faster dissection speed than controls (21.6 mm²/min; IQR 15.5-28.8 mm ² /min vs. 14.4 mm ² /min; IQR 9.9-21.2 mm ² /min) ( <i>P</i> = 0.009).</p><p><strong>Conclusions: </strong>This multicenter randomized trial demonstrated that use of MLTD did not significantly increase dissection speed for colorectal ESD. Treatment conversions may have influenced the primary endpoint, and further investigation is warranted.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a24660718"},"PeriodicalIF":2.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing endoscopic detection of precancerous gastric conditions: Single-center prospective study.","authors":"Jennifer Aoun, Elena Unger, Mohamed Abdessalami, Amélie Bourgeois, Maria Galdon Gomez, Laurine Verset, Mariana Figueiredo, Pierre Eisendrath","doi":"10.1055/a-2557-6356","DOIUrl":"https://doi.org/10.1055/a-2557-6356","url":null,"abstract":"<p><strong>Background and study aims: </strong>Chronic atrophic gastritis is an asymptomatic precancerous condition that can progress to extensive atrophy and/or intestinal metaplasia (IM), referred to as advanced stage of atrophic gastritis (ASAG). ASAG is a common condition with a variable prevalence worldwide reaching 45%. Narrow-band imaging (NBI) already has an established role in improving endoscopic detection of atrophy and IM. Considering the heterogeneous hospital population, this study aimed to assess the ASAG detection rate with NBI-guided biopsies compared with conventional Sydney protocol, in a European cosmopolitan city hospital.</p><p><strong>Patients and methods: </strong>This was a prospective, single-center, bi-phasic study conducted between October 2023 and March 2024, comparing ASAG detection rates using conventional Sydney protocol with optional NBI use, defined as phase 1, versus systematic NBI-guided biopsies in phase 2.</p><p><strong>Results: </strong>Of 495 eligible patients, 435 with similar demographics were included in both phases (87.8%). ASAG was detected in three patients using conventional Sydney protocol (1.43%) compared with eight patients (3.56%) using systematic NBI-guided biopsies ( <i>P</i> = 0.269). Furthermore, systematic NBI-guided biopsies were associated with increased detection rates for atrophy and IM ( <i>P</i> = 0.223 and <i>P</i> = 0.502, respectively). Suspicion-free NBI use correlated with increased likelihood of ASAG detection (odds ratio 16.99, 95% confidence interval 2.30-213.73). Age ≥ 50 years was a significant risk factor associated with ASAG.</p><p><strong>Conclusions: </strong>Despite the diverse hospital population, ASAG prevalence remained low. A numerical increase in ASAG detection rate was observed with systematic NBI use compared with optional NBI use. Overall, systematic NBI-guided biopsies appear to be associated with increased rates of detection of ASAG, atrophy, and IM.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a25576356"},"PeriodicalIF":2.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis of small bowel inflammation using small bowel capsule endoscopy combined with abdominal CT scan.","authors":"Kentaro Ito, Tomoyoshi Shibuya, Hirotaka Ishino, Masashi Omori, Rina Odakura, Masao Kouma, Takafumi Maruyama, Kei Nomura, Osamu Nomura, Dai Ishikawa, Akihito Nagahara","doi":"10.1055/a-2560-4839","DOIUrl":"https://doi.org/10.1055/a-2560-4839","url":null,"abstract":"<p><strong>Background and study aims: </strong>Abdominal computed tomography (CT) scans are simple to perform and widely used in evaluating small bowel inflammation. However, detailed evaluation of small intestinal mucosa is difficult with CT. Conversely, small bowel capsule endoscopy (SBCE) is noninvasive and useful for evaluation of mucosal inflammation. We evaluated presence or absence of mucosal inflammation by SBCE in patients with CT findings of suspected small bowel inflammation and analyzed their backgrounds.</p><p><strong>Patients and methods: </strong>The Lewis score was determined by SBCE, and scores ≥ 135 placed 65 patients in the enteritis group and scores of < 135 placed 87 patients in the pseudoenteritis group.</p><p><strong>Results: </strong>Blood tests revealed higher C-reactive protein (CRP) levels in the enteritis group ( <i>P</i> < 0.01). Regarding comorbidities, chronic renal failure ( <i>P</i> < 0.01) and carcinoma ( <i>P</i> = 0.05) were more common in the enteritis group, as was use of proton pump inhibitors ( <i>P</i> = 0.02). Target sign, accordion sign, and fat stranding/centipede sign, which are known findings on CT of small intestinal inflammation, were more frequently observed in the enteritis group ( <i>P</i> < 0.01). Small intestinal wall thickness was greater in the enteritis group (5.3 mm vs 3.4 mm, <i>P</i> < 0.01) and the cut-off value was 4.15 mm.</p><p><strong>Conclusions: </strong>Backgrounds of patients with inflammatory mucosa included high CRP, use of nonsteroidal anti-inflammatory medications, chronic renal failure, and cancer. If a patient with a thickened small intestinal wall (> 4.15 mm) on CT has these characteristics, it may be worth considering performing SBCE.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a25604839"},"PeriodicalIF":2.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic intermuscular dissection for management of 10- to 20-mm rectal neuroendocrine tumors: Pilot study (with video).","authors":"Silin Huang, Bo Li, Huizhao Deng, Guang Yang, Ronggang Zhang, Jianzhen Ren, Nan Liu, Suhuan Liao","doi":"10.1055/a-2549-9852","DOIUrl":"https://doi.org/10.1055/a-2549-9852","url":null,"abstract":"<p><strong>Background and study aims: </strong>Endoscopic intermuscular dissection (EID) is associated with higher rates of negative margins in treating rectal neuroendocrine tumors (R-NETs), as reported in case studies. However, evidence regarding the safety and effectiveness of EID remains insufficient. This study aimed to evaluate clinical safety and effectiveness of EID in treating 10- to 20-mm R-NETs.</p><p><strong>Patients and methods: </strong>Retrospective clinical data from patients with 10- to 20-mm R-NETs who had undergone EID from 2019 to 2024 were collected from a tertiary hospital. The primary outcome was the histological complete resection rate and secondary outcomes included en bloc resection rate and technical success rate.</p><p><strong>Results: </strong>Twelve patients who had undergone EID were included, with one patient excluded for pathology indicative of a leiomyoma. Among the 11 patients (mean age, 42.45 years; 72.73% males), median diameter was 11.55 mm (interquartile range 10-13 mm). All patients underwent en bloc resection and postoperative pathology confirmed negative horizontal and vertical margins, achieving a histological complete resection rate of 100%. Mean procedure time was 58.55 minutes (standard deviation [SD] 13.66 minutes) and mean postoperative hospital stay was 5.7 days (SD 1.00). One patient developed fever and another experienced abdominal pain, both of which resolved within 24 hours. There were no cases of bleeding or perforation intraoperatively or postoperatively. During a mean follow-up of 31.73 months, there were no residual tumors, local recurrences, or metastases.</p><p><strong>Conclusions: </strong>EID is a promising treatment for 10- to 20-mm R-NETs, with high initial cure rates, and a new option for endoscopic resection. More studies of the procedure are needed.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a25499852"},"PeriodicalIF":2.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11998635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}