Tarek Arraf, Yuri Gorelik, Fares Mazzawi, Halim Awadie, Suzan Banna, Rawia Moalem, Nour Ershaid, Rashad Falah, Andrew Beany, Itay Maza, Amir Klein
{"title":"Delayed surveillance colonoscopy after piecemeal EMR is not associated with increased recurrence rates.","authors":"Tarek Arraf, Yuri Gorelik, Fares Mazzawi, Halim Awadie, Suzan Banna, Rawia Moalem, Nour Ershaid, Rashad Falah, Andrew Beany, Itay Maza, Amir Klein","doi":"10.1055/a-2816-4998","DOIUrl":"https://doi.org/10.1055/a-2816-4998","url":null,"abstract":"<p><strong>Background and study aims: </strong>First surveillance colonoscopy (SC1) following piecemeal endoscopic mucosal resection (pEMR) is recommended at 3 to 6 months. We aimed to investigate whether delayed SC1 is associated with increased risk of recurrence.</p><p><strong>Patients and methods: </strong>This was a retrospective analysis of a prospective cohort of patients undergoing pEMR for large non-pedunculated colorectal polyps (LNPCPs). Patients were categorized into standard SC1 (3-6 months) and delayed SC1 (> 6 months) groups. The primary endpoint was recurrence at SC1. Secondary outcomes included recurrence at second surveillance colonoscopy (SC2) and features of lesion recurrence. Subgroup analyses of very delayed SC1 and high-risk lesions were performed. Recurrence rates were also evaluated with propensity score matching (PSM).</p><p><strong>Results: </strong>We analyzed 577 lesions (standard: 407, delayed: 170) with a median polyp size of 30 mm (interquatile range [IQR] 25-40). Median time to SC1 was 5 months (IQR 5-6) in the standard versus 9 months (IQR 7-13) in the delayed group ( <i>P</i> < 0.01). There were no significant differences in SC1 recurrence rates between groups (6.4% versus 6.5% in the standard and delayed respectively, <i>P</i> = 1). At SC2, recurrence rate was also similar between groups (3.8% versus 8.8% respectively, <i>P</i> = 0.43). Recurrence rates did not differ significantly among the analyzed subgroups. Recurrence rates did not differ significantly among the analyzed subgroups or in the PSM analyses. No advanced recurrences were detected at SC1 or SC2.</p><p><strong>Conclusions: </strong>Delayed SC1 is not associated with increased recurrence rates. Complete resection can be anticipated for most lesions and SC1 at 1-year post resection may be sufficient.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28164998"},"PeriodicalIF":2.3,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13063303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Real-world practices and barriers in endoscopic submucosal dissection training: International comprehensive survey.","authors":"Giulio Calabrese, Marcello Maida, Shaimaa Elkholy, Manol Jovani, David J Tate, Hugo Uchima, Yohei Minato, Partha Pal, Sunil Gupta, Rui Morais, Torsten Beyna, Jeremie Jacques, Sandro Sferrazza","doi":"10.1055/a-2813-3195","DOIUrl":"https://doi.org/10.1055/a-2813-3195","url":null,"abstract":"<p><strong>Background and study aims: </strong>Endoscopic submucosal dissection (ESD) enables curative resection of superficial gastrointestinal neoplasia but requires structured training. Although European Society of Gastrointestinal Endoscopy (ESGE)/American Society for Gastrointestinal Endoscopy (ASGE) curricula exist, real-world practices and barriers remain unclear.</p><p><strong>Methods: </strong>We conducted an anonymous web-based survey (April-July 2025) with 55 items assessing training opportunities, barriers, curriculum adherence, and quality metrics, stratified by role and annual ESD volume.</p><p><strong>Results: </strong>We received 288 responses (137 trainees, 151 trainers) from 39 countries across five geographic macro-areas. Nearly half (47.2%) had undertaken structured training, but only 46.5% fulfilled ESGE/ASGE curricula, with marked variation by center volume (69.6% in high-volume vs 26.8% in low-volume, <i>P</i> < 0.001). Lack of access to training models was reported by 46.5% overall, more frequently in low-volume centers. In vivo human training, animal models, and intensive courses were rated highest, whereas lack of simulators, fellowship costs, and limited time were leading barriers. Quality monitoring was reported in 62.5% of centers, prioritizing R0 and en bloc resection rates over procedure speed. Trainees valued traction and underwater techniques more than trainers. Regional differences were pronounced: North-West Europe and Asia-Pacific concentrated high-volume centers and greater curriculum adherence, whereas Africa/Middle East and South-East Europe faced resource and financial constraints.</p><p><strong>Conclusions: </strong>This international survey reveals substantial disparities in ESD training and calls for coordinated efforts to improve access to structured curricula, mentorship, and affordable training models.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28133195"},"PeriodicalIF":2.3,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147688837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobias Blasberg, Lukas Hiebel, Moritz Meiborg, Johannes Richl, Florian Alexander Michael, Ali Seif Amir Hosseini, Ahmad Amanzada, Volker Ellenrieder, Juergen Hochberger, Wedi Edris
{"title":"Endoloop-assisted endoscopic removal of over-the-scope and full-thickness resection device clips: Prospective study.","authors":"Tobias Blasberg, Lukas Hiebel, Moritz Meiborg, Johannes Richl, Florian Alexander Michael, Ali Seif Amir Hosseini, Ahmad Amanzada, Volker Ellenrieder, Juergen Hochberger, Wedi Edris","doi":"10.1055/a-2784-8740","DOIUrl":"https://doi.org/10.1055/a-2784-8740","url":null,"abstract":"<p><strong>Background and study aims: </strong>The over-the-scope (OTS) clip system is an established tool for endoscopic management of gastrointestinal bleeding, perforations, fistulas, and, in its modified form as the full-thickness resection device (FTRD), for resection of gastrointestinal lesions. In selected cases, clip removal is required. Conventional techniques often demand costly devices and may be time-consuming. This study evaluated a novel, simple technique for endoscopic removal of OTS and FTRD clips using an endoloop, focusing on feasibility and safety.</p><p><strong>Patients and methods: </strong>This prospective single-center study included patients who had undergone OTS or FTRD clip placement and required clip removal between March 2021 and October 2024. The removal procedure involved positioning an endoloop underneath the clip. Follow-up endoscopy within 6 months assessed clip detachment. The primary endpoint was the success rate for clip removal; the secondary endpoint was incidence of adverse events (AEs).</p><p><strong>Results: </strong>A total of 18 patients underwent endoloop-assisted removal of OTS (50%, 9/18) or FTRD (50%, 9/18) clips. Endoloop placement was performed at a median of 94 days (range: 27-472) after OTS clip placement and 97 days (range: 0-274) after EFTR. Follow-up endoscopy confirmed clip detachment after a median of 107 days (range: 33-220) for OTS and 114 days (range: 5-203) for FTRD clips. Clip removal was successful in all patients (100%), with no AEs observed.</p><p><strong>Conclusions: </strong>Endoloop-assisted removal of OTS and FTRD clips appears to be effective and safe, representing an addition to current options for endoscopic clip removal.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a27848740"},"PeriodicalIF":2.3,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147688868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of a novel endoscopic device in treatment of gastric bezoars: Pilot study.","authors":"Jia Xu, Weixing Yang, Xian Zhou, Xuanli Wang, Xia Luo, Haitao Zhang, Mingming Deng, Lei Shi, Xiaowei Tang","doi":"10.1055/a-2811-5338","DOIUrl":"https://doi.org/10.1055/a-2811-5338","url":null,"abstract":"<p><p>Gastric bezoars, especially phytobezoars, are often challenging to treat due to their large size, hardness, and poor response to conventional endoscopic methods, frequently necessitating surgery. This study presents a novel endoscopic device designed to fragment and remove gastric bezoars as a safer and more efficient alternative. In a retrospective single-center study at the Affiliated Hospital of Southwest Medical University, nine patients with giant gastric bezoars (long axis > 3 cm) were treated using this device between November 2023 and March 2025. The device features two outer sheaths symmetrically attached to the lens body, aligned with a transparent cap, and a yellow zebra guidewire running through the sheaths. The guidewire length can be adjusted to modify the snare size, allowing precise bezoar fragmentation. Patients underwent gastroscopy before and after treatment, with follow-up after 1 month. The device successfully fragmented and removed bezoars in all patients, with an average procedure time of approximately 66 minutes (range 33-113 minutes). No complications occurred and follow-up gastroscopy confirmed complete bezoar removal with significant symptom improvement. The novel endoscopic device demonstrated high efficacy and safety in treating gastric bezoars, offering a promising alternative to surgical intervention.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28115338"},"PeriodicalIF":2.3,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13093226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147765954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salvador Machlab, Vicente Lorenzo-Zúñiga, Miguel Angel Pantaleon, Fernando Sábado, Cátia Arieira, Elena Pérez Arellano, José Cotter, David Carral, Carmen Turbí Disla, Ricardo Gorjão, Jose Miguel Esteban, Sarbelio Rodriguez
{"title":"Correction: Real-world effectiveness and safety of 1L polyethylene glycol and ascorbic acid for bowel preparation in patients aged 80 years or older.","authors":"Salvador Machlab, Vicente Lorenzo-Zúñiga, Miguel Angel Pantaleon, Fernando Sábado, Cátia Arieira, Elena Pérez Arellano, José Cotter, David Carral, Carmen Turbí Disla, Ricardo Gorjão, Jose Miguel Esteban, Sarbelio Rodriguez","doi":"10.1055/a-2822-5767","DOIUrl":"https://doi.org/10.1055/a-2822-5767","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1055/a-2525-9938.].</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28225767"},"PeriodicalIF":2.3,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nilanga Nishad, Syrine Ben Rhouma, Visula Abeysuriya, Mo Thoufeeq
{"title":"Reply to Koulaouzidis and Marlicz.","authors":"Nilanga Nishad, Syrine Ben Rhouma, Visula Abeysuriya, Mo Thoufeeq","doi":"10.1055/a-2808-4415","DOIUrl":"https://doi.org/10.1055/a-2808-4415","url":null,"abstract":"","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28084415"},"PeriodicalIF":2.3,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12951188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of benign biliary strictures with expandable biodegradable stents: Safety and efficacy in a single center.","authors":"Gabriel Marcellier, Abdellah Hedjoudje, Benedicte Jais, Frederique Maire, Kenza Bourhrara, Alain Berson, Fabiano Perdigao, Olivier Scatton, Heithem Soliman, Paul Rivallin, Frédéric Prat","doi":"10.1055/a-2813-3346","DOIUrl":"https://doi.org/10.1055/a-2813-3346","url":null,"abstract":"<p><strong>Background and study aims: </strong>Benign biliary strictures (BBS) are commonly managed by progressive calibration using plastic or metallic stents. Although fully-covered metallic stents (FC-SEMS) enable immediate calibration to a larger diameter compared with plastic stents, they remain prone to migration and use is limited in intrahepatic and peri-hilar strictures. We report on using uncovered expandable bioresorbable stents (BRES) in a series of selected BBS patients.</p><p><strong>Patients and methods: </strong>This retrospective monocentric case series included all consecutive patients treated between 2023 and 2024. Patients were highly selected for uncommon situations for which usual stents were not well suited and followed for at least 12 months after the procedure. Technical success, clinical success, and adverse events (AEs) were systematically recorded.</p><p><strong>Results: </strong>Five procedures were performed in five patients with implantation of a total of eight UNITY-B stents. Three patients underwent internalization of an internal-external drainage across a bilio-digestive anastomotic stricture. One patient was treated with retrograde extra-anatomical endoscopic drainage for an anastomotic stricture. One patient underwent calibration of an intrahepatic stricture following radiofrequency of an IPMN-B. Technical success was achieved in all cases (100%), with clinical success observed in 80% of patients. No AEs were observed.</p><p><strong>Conclusions: </strong>Use of bioresorbable UNITY-B stents appears feasible and safe for selected benign biliary strictures, including in intrahepatic locations. Further studies are needed to confirm these preliminary findings.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28133346"},"PeriodicalIF":2.3,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12951189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tony He, Mark Lai, Kiran G Iyer, Sara Vogrin, John L Slavin, Edward H Tsoi, Bronte Holt, Paul Desmond, Andrew Cf Taylor
{"title":"Long-term outcomes of surveillance or endoscopic therapy for low-grade dysplastic Barrett's according to a selective management algorithm.","authors":"Tony He, Mark Lai, Kiran G Iyer, Sara Vogrin, John L Slavin, Edward H Tsoi, Bronte Holt, Paul Desmond, Andrew Cf Taylor","doi":"10.1055/a-2778-3907","DOIUrl":"https://doi.org/10.1055/a-2778-3907","url":null,"abstract":"<p><strong>Background and study aims: </strong>Current European and American guidelines conflict in their recommendations for surveillance versus endoscopic therapy for low-grade dysplastic Barrett's (LGD). We aimed to evaluate the performance of a selective management algorithm and provide real-world outcomes.</p><p><strong>Patients and methods: </strong>Data on 497 patients with dysplastic Barrett's were collected prospectively between 2008 and 2022 at a Barrett's referral unit. LGD was defined as confirmation of LGD by an expert gastrointestinal pathologist. Persistent unifocal LGD or multifocal LGD were considered high-risk features for progression and patients underwent endoscopic eradication therapy (EET). Patients with non-persistent unifocal LGD were deemed low-risk and were surveilled. Primary outcome was progression rate to high grade dysplasia or neoplasia.</p><p><strong>Results: </strong>A total of 135 patients had LGD (median [interquartile range] follow up: 4.8 years [1.0-7.1]): 22 patients met low-risk criteria and were surveilled (LR-S), eight patients met high-risk criteria and were surveilled (HR-S; patient preference n = 4, medical comorbidities n = 4), and 105 patients met high-risk criteria and underwent EET (HR-EET). Progression rates were similar between the LR-S and HR-EET cohorts (4.5% [n = 1/22] vs. 6.7% [n = 8/105]; <i>P</i> = 0.43). The HR-S group had a significantly higher progression rate (25% [n = 2/8]; <i>P</i> = 0.04). Univariable analysis showed reflux esophagitis (sub-distribution hazard ratio 3.21, 95% confidence interval 1.02-10.1, <i>P</i> = 0.04) was associated with progression risk in the high-risk LGD cohort only.</p><p><strong>Conclusions: </strong>This selective management algorithm for LGD is safe. Surveillance is appropriate in low-risk LGD patients. Patients with high-risk features who are surveilled and/or have reflux esophagitis may have an increased progression risk and should undergo EET with optimized acid suppression therapy.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a27783907"},"PeriodicalIF":2.3,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12951032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Size, morphology, site, and access scoring variability as a barrier to standardization and automation.","authors":"Anastasios Koulaouzidis, Wojciech Marlicz","doi":"10.1055/a-2808-4380","DOIUrl":"https://doi.org/10.1055/a-2808-4380","url":null,"abstract":"","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28084380"},"PeriodicalIF":2.3,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12951036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}