Endoscopy International Open最新文献

{"title":"Validation and efficacy of the Varix Trainer model as a Training device for esophagogastroduodenoscopy.","authors":"Sarunporn Kamolvisit, Julajak Limsrivilai, Parit Mekaroonkamol, Tanyaporn Chantarojanasiri, Nalerdon Chalermsuksant, Kamin Harinwan, Chitchai Rattananukrom, Thanawin Wong, Rapat Pittayanon, Onuma Sattayalertyanyong, Phalat Sathirawich, Uayporn Kaosombatwattana, Akharawit Pulsombat, Patarapong Kamalaporn, Jaksin Sottisuporn, Nonthalee Pausawasdi, Sasivimol Rattanasiri, Taya Kitiyakara","doi":"10.1055/a-2374-8476","DOIUrl":"https://doi.org/10.1055/a-2374-8476","url":null,"abstract":"<p><p><b>Background and study aims</b> The Varix Trainer model 1 (VTM1) was created for trainees to safely practice basic endoscope manipulation skills. The VTM1 was tested to see if it could distinguish levels of endoscope manipulation skills (construct validity) and whether training with it could improve these skills faster (content validity). <b>Patients and methods</b> We enrolled 23 novice endoscopists, 18 second-year trainees, and 13 expert endoscopists. They were asked to point with the endoscope tip to 20 numbers in the model as quickly as possible using torque, single-hand small/large wheel manipulation (SHSW), and retroflexion techniques. Their mean times (t20) were compared to determine if the model could distinguish different levels of expertise. Subsequently, 14 novices trained for eight short sessions, and the pre-training and post-training t20 were compared. Nine novice endoscopists received no training and were retested after 4 to 6 weeks (controls). <b>Results</b> Experts had faster t20 than second-year trainees, who were faster than novices, for all three techniques ( <i>P</i> < 0.001). After eight sessions, the mean t20 for novices improved from 112 to 66 seconds for torque, 144 to 72 seconds for SHSW, and 108 to 63 seconds for retroflexion, (all <i>P</i> < 0.001). Their t20 were equivalent to second-year trainees. Improvement in t20 was also seen with the control group, but total reduction was less than for the training group. <b>Conclusions</b> The VTM1 distinguished varying levels of expertise for all techniques, suggesting that it is a valid tool for assessing endoscope manipulation skill. A short curriculum improved novices' manipulation skills faster than traditional practice.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"12 9","pages":"E1043-E1055"},"PeriodicalIF":2.2,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detective flow imaging endoscopic ultrasound for locating optimal puncture site for a poorly vascularized pancreatic mass.","authors":"Yasuo Otsuka, Kosuke Minaga, Akane Hara, Yasuhiro Masuta, Mamoru Takenaka, Takaaki Chikugo, Masatoshi Kudo","doi":"10.1055/a-2405-1170","DOIUrl":"https://doi.org/10.1055/a-2405-1170","url":null,"abstract":"","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"12 9","pages":"E1063-E1064"},"PeriodicalIF":2.2,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lymphovascular invasion is a dominant risk factor for lymph node metastasis in T2 rectal cancer.","authors":"Selma Medic, Emelie Nilsson, Carl-Fredrik Rönnow, Henrik Thorlacius","doi":"10.1055/a-2405-1117","DOIUrl":"https://doi.org/10.1055/a-2405-1117","url":null,"abstract":"<p><p><b>Background and study aims</b> Surgical resection is standard treatment of T2 rectal cancer due to risk of concomitant lymph node metastases (LNM). Local resection could potentially be an alternative to surgical treatment in a subgroup of patients with low risk of LNM. The aim of this study was to identify clinical and histopathological risk factors of LNM in T2 rectal cancer. <b>Patients and methods</b> This was a retrospective registry-based population study on prospectively collected data on all patients with T2 rectal cancer undergoing surgical resection in Sweden between 2009 and 2021. Potential risk factors of LNM, including age, gender, resection margin, lymphovascular invasion (LVI), histologic grade, mucinous cancer, and perineural invasion (PNI) were analyzed using univariate and multivariate logistic regression. <b>Results</b> Of 1607 patients, 343 (21%) with T2 rectal cancer had LNM. LVI (odds ratio [OR] = 4.21, <i>P</i> < 0.001) and age < 60 years (OR = 1.80, <i>P</i> < 0.001) were significant and independent risk factors. However, PNI (OR = 1.50, <i>P</i> = 0.15), mucinous cancer (OR = 1.14, <i>P</i> = 0.60), histologic grade (OR = 1.47, <i>P</i> = 0.07) and non-radical resection margin (OR = 1.64, <i>P</i> = 0.38) were not significant risk factors for LNM in multivariate analyses. The incidence of LNM was 15% in the absence of any risk factor. <b>Conclusions</b> This was a large study on LNM in T2 rectal cancer which showed that LVI is the dominant risk factor. Moreover, low age constituted an independent risk factor, whereas gender, resection margin, PNI, histologic grade, and mucinous cancer were not independent risk factors of LNM. Thus, these findings may provide a useful basis for management of patients after local resection of early rectal cancer.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"12 9","pages":"E1056-E1062"},"PeriodicalIF":2.2,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of radial incision and cutting for nonsurgical refractory benign esophageal stricture.","authors":"Yosuke Mitani, Kenshiro Hirohashi, Masashi Tamaoki, Akira Yokoyama, Chikatoshi Katada, Aya Ueda, Natsuko Yamahigashi, Hirokazu Higuchi, Manabu Muto","doi":"10.1055/a-2382-6213","DOIUrl":"https://doi.org/10.1055/a-2382-6213","url":null,"abstract":"<p><p><b>Background and study aims</b> Radial incision and cutting (RIC) was established to improve refractory esophageal anastomotic strictures but its efficacy and safety for nonsurgical refractory strictures remain unclear. To evaluate the usefulness of RIC in nonsurgical refractory strictures, we retrospectively compared outcomes between nonsurgical and surgical strictures. <b>Patients and methods</b> We retrospectively studied 54 consecutive patients who were initially treated with RIC for refractory benign esophageal stricture. The study variables included dysphasia score improvement rate, frequency of repeated RIC, cumulative patency rate, cumulative stricture improved rate, and adverse events(AEs), which were compared between nonsurgical (n = 21) and surgical (n = 33) stricture groups. <b>Results</b> Immediately after RIC, 90.5% of patients in the nonsurgical group and 84.8% of patients in the surgical group had improvement in dysphagia ( <i>P</i> = 0.69). The frequency of intervening repeated RIC was 42.9% in the nonsurgical group and 42.4% in the surgical group ( <i>P</i> = 0.98). During median follow-up of 22.3 months (range, 1.0-175.0), the cumulative patency rate ( <i>P</i> = 0.23) and cumulative stricture improvement rate ( <i>P</i> = 0.14) but there was not statistical difference between the two groups. Despite a low cumulative stricture improvement rate (9.5%) at 6 months after the first RIC in the nonsurgical group, 57.7% of patients no longer required endoscopic balloon dilatation at 2 years. The cumulative stricture improvement rate was significantly lower in patients with a history of radiation therapy. No severe AEs were observed in the nonsurgical group. <b>Conclusions</b> RIC for nonsurgical refractory benign esophageal stricture is an effective and safe treatment option.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"12 9","pages":"E1035-E1042"},"PeriodicalIF":2.2,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11387040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of an ultrathin endoscope in esophageal endoscopic submucosal dissection.","authors":"Daisuke Kikuchi, Yugo Suzuki, Yusuke Kawai, Kosuke Nomura, Yorinari Ochiai, Junnosuke Hayasaka, Yutaka Mitsunaga, Takayuki Okamura, Hiroyuki Odagiri, Satoshi Yamashita, Akira Matsui, Masami Tanaka, Shu Hoteya","doi":"10.1055/a-2386-9660","DOIUrl":"https://doi.org/10.1055/a-2386-9660","url":null,"abstract":"<p><p><b>Background and study aims</b> Endoscopic submucosal dissection (ESD) is sometimes challenging because of stenosis and scarring. We examined the use of an ultrathin endoscope for esophageal ESD, which is difficult using conventional endoscopes. <b>Patients and methods</b> A designated transparent hood and ESD knife for ultrathin endoscopes have been developed and clinically introduced. Esophageal ESD was performed on 303 lesions in 220 patients in our hospital from February 2021 to February 2023. Of them, an ultrathin endoscope was used on 26 lesions in 23 cases. The safety and utility of an ultrathin endoscope in esophageal ESD were retrospectively verified. <b>Results</b> All 26 lesions were resected en bloc, and serious complications such as perforation, massive bleeding, or pneumonia, were not observed. Lesions were found on the anal side of the stenosis and over the scarring in 38.6% (10/26) and 50% (13/26) of participants, respectively. Moreover, 46.2% of participants (12/26) had lesions on the cervical esophagus. The total procedure time was 64.1 ± 37.7 minutes, but the average time from oral incision to pocket creation was 121.2 ± 109.9 seconds. <b>Conclusions</b> Ultrathin endoscopes may be useful for difficult esophageal ESD.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"12 9","pages":"E1029-E1034"},"PeriodicalIF":2.2,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11387091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Additional over-the-scope-clip closure can shorten endoscopic vacuum therapy for postoperative upper gastrointestinal leakage.","authors":"Lars Kollmann, Alexander Weich, Maximilian Gruber, Sven Flemming, Alexander Meining, Christoph-Thomas Germer, Johann Friso Lock, Florian Seyfried, Markus Brand, Stanislaus Reimer","doi":"10.1055/a-2387-2054","DOIUrl":"https://doi.org/10.1055/a-2387-2054","url":null,"abstract":"<p><p><b>Background and study aims</b> Endoscopic vacuum therapy (EVT) has become the most effective therapeutic option for upper gastrointestinal leakage. Despite its efficiency, this treatment can necessitate a long hospitalization. The aim of this study was to evaluate whether additional use of an over-the-scope-clips (OTSC) closure after successful EVT can shorten leakage therapy. <b>Patients and methods</b> All patients treated with EVT for leakages in the upper gastrointestinal tract at our center from 2012 to 2022 were divided into two propensity matched cohorts (EVT+OTSC vs. EVT only). The EVT+OTSC patients received OSTC application at the end of successful EVT directly after removal of the last sponge. The primary endpoint was the time interval from leakage diagnosis until discharge. Secondary endpoints included EVT efficacy, complications, and nutritional status at discharge. <b>Results</b> A total of 84 matched patients were analyzed. EVT efficacy was 100% in both groups. The time interval from leakage until discharge was significantly shorter in the EVT+OTSC vs. EVT group (33 [19-48] vs. 46 days [29-77] <i>P</i> = 0.004). No patient in the EVT+OTSC group required additional procedures for leakage management, whereas five (12%) in the EVT group needed additional stent placement ( <i>P</i> = 0.021). More patients could be discharged on sufficient oral nutrition in the EVT+OTSC group (98% vs. 60%; <i>P</i> < 0.001). <b>Conclusions</b> The addition of OTSCs after successful EVT is safe and has the potential to shorten leakage therapy, enabling earlier discharge along with better functional outcomes.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"12 9","pages":"E1023-E1028"},"PeriodicalIF":2.2,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11383616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When to remove a lumen-apposing metal stent for pancreatic fluid collections?","authors":"Tomotaka Saito, Takuji Iwashita, Shunsuke Omoto, Yousuke Nakai, Hiroyuki Isayama","doi":"10.1055/a-2308-3777","DOIUrl":"10.1055/a-2308-3777","url":null,"abstract":"","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"12 8","pages":"E996-E997"},"PeriodicalIF":2.2,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome after colorectal full-thickness resection and management of recurrence.","authors":"Julius Mueller, Valentin Miedtke, Armin Kuellmer, Moritz Schiemer, Dominik Bettinger, Robert Thimme, Arthur Schmidt","doi":"10.1055/a-2375-7568","DOIUrl":"10.1055/a-2375-7568","url":null,"abstract":"<p><p><b>Background and study aims</b> Endoscopic full-thickness resection (eFTR) allows treatment of \"difficult to resect\" lesions not amenable to conventional endoscopic methods. Efficacy and safety of the system have already been proven in numerous studies. Follow-up data on outcome of colorectal eFTR and management of recurrences are still rare. <b>Patients and methods</b> All patients undergoing colorectal eFTR at our institution with at least one endoscopic follow-up examination were retrospectively analyzed. The primary endpoint was the rate of recurrent or residual lesions (RRLs) and the secondary endpoint was the rate of late adverse events (AEs). We further aimed to identify risk factors for RRLs and to describe their management. <b>Results</b> Between November 2014 and 2021, 141 patients underwent eFTR at University Medical Center Freiburg. Ninety-one patients fulfilled the inclusion criteria. Indications for eFTR were non-lifting adenoma (n = 65), subepithelial tumors (n = 18) and early carcinoma (n = 8). The median follow-up period was 17 months (range, 2-86). The overall RRL rate was 9.9% (9/91). A significant proportion of RRLs (6/9, 66%) were detected late. All RRLs occurred in the group of non-lifting adenoma, corresponding to a RRL rate of 13.8% in this subgroup. Thirty-three percent (3/9) were initially treated by hybrid eFTR. Of the RRLs, 66.6% could were successfully treated endoscopically. On χ2 analysis, the hybrid eFTR technique ( <i>P</i> = 0.006) was associated with a higher rate of RRL. No late AEs occurred. <b>Conclusions</b> The rate of RRL after colorectal eFTR is low and the majority could be treated endoscopically. For non-lifting adenomas and early carcinomas, close follow-up is mandatory to detect late recurrence. Long-term outcomes after hybrid eFTR need further investigation.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"12 8","pages":"E989-E995"},"PeriodicalIF":2.2,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142055250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct endoscopic necrosectomy: Pilot study of a new dedicated device.","authors":"Dario Ligresti, Cecilia Binda, Alessandro Fugazza, Marcello Maida, Mario Traina, Andrea Anderloni, Carlo Fabbri, Ilaria Tarantino","doi":"10.1055/a-2376-1913","DOIUrl":"10.1055/a-2376-1913","url":null,"abstract":"<p><p><b>Background and study aims</b> Direct endoscopic necrosectomy (DEN) represents the first-line treatment for walled-off necrosis (WON). However, DEN has a non-negligible rate of overall adverse events (AE) and is time-consuming due to the lack of dedicated devices. This pilot study was designed to evaluate the feasibility and safety of a novel dedicated device for DEN named Necrolit. <b>Patients and methods</b> In this multicenter retrospective analysis,16 patients with WON who underwent DEN using Necrolit were compared with a control group treated with non-dedicated devices. Technical success, AEs, clinical success, number of procedures per patient, procedure time, and length of hospital stay were evaluated. Necrolit technical performance indicators were also studied. <b>Results</b> Technical success was obtained in all patients in both groups. In the Necrolit group, the overall AE rate was 10.1% vs. 15.9% in the control group. Clinical success was 100% in the Necrolit group vs. 81.3% in the control group. Patients treated with Necrolit underwent a slightly lower mean number of procedures (4.1 ± 2.3 vs. 5.1 ± 1.9) with comparable mean procedure time (67.8 ± 39 minutes vs. 70.1 ± 32.6 minutes). Mean duration of hospital stay was 39.4 days (± 30.9) in the Necrolit group vs. 43 days (± 29.4) in the control group. Device-related technical performance was rated positively. <b>Conclusions</b> DEN with Necrolit appears feasible and safe.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"12 8","pages":"E962-E967"},"PeriodicalIF":2.2,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142055249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcecal endoscopic appendectomy for management of complex appendiceal polyps extending into the appendiceal orifice.","authors":"Tara Keihanian, Mai A Khalaf, Fuad Zain Aloor, Dina Hani Zamil, Salmaan Jawaid, Mohamed O Othman","doi":"10.1055/a-2356-6711","DOIUrl":"10.1055/a-2356-6711","url":null,"abstract":"<p><p><b>Background and study aims</b> Endoscopic resection of appendiceal orifice (AO) polyps extending inside the appendiceal lumen is challenging given the inability to determine polyp lateral margins and risk of appendicitis. Transcecal endoscopic appendectomy (TEA) ensures en bloc resection of these complex polyps. <b>Patients and methods</b> This case series includes patients who underwent TEA by a single endoscopist in the United States. Technical success was defined as achieving complete removal of the appendix along with AO polyp in an en bloc fashion. <b>Results</b> In total, nine patients were included (mean age 69.7 ± 9.6 years). The average appendix size was 4.07 ± 2.02 cm. Technical success was achieved in 100% of the patients. The average procedure length was 118.1 ± 44.21 minutes. The en bloc resection rate, R0 resection rate, and curative resection rates were 100%. Patients were observed for an average of 3.1 ± 1.6 days. One patient developed loculated fluid collection 9 days post procedure, which resolved on its own with oral antibiotic therapy. No other adverse events were recorded. <b>Conclusions</b> This was an early study of the feasibility of TEA in the United States. This novel technique, in early-stage development, is potentially safe and associated with a minimal risk profile in expert hands. Further prospective studies are needed to standardize the technique.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"12 8","pages":"E932-E939"},"PeriodicalIF":2.2,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}