Advanced Materials最新文献_第9页

Enhancing Radiofrequency Ablation for Hepatocellular Carcinoma: Nano‐Epidrug Effects on Immune Modulation and Antigenicity Restoration 加强射频消融治疗肝细胞癌：纳米表皮药物对免疫调节和抗原性恢复的影响

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2024-11-16 DOI: 10.1002/adma.202414365

Xiaocheng Li, Yahui Liu, Jianji Ke, Zhihua Wang, Mingda Han, Ning Wang, Qiannan Miao, Bingru Shao, Dan Zhou, Fei Yan, Bai Ji

{"title":"Enhancing Radiofrequency Ablation for Hepatocellular Carcinoma: Nano‐Epidrug Effects on Immune Modulation and Antigenicity Restoration","authors":"Xiaocheng Li, Yahui Liu, Jianji Ke, Zhihua Wang, Mingda Han, Ning Wang, Qiannan Miao, Bingru Shao, Dan Zhou, Fei Yan, Bai Ji","doi":"10.1002/adma.202414365","DOIUrl":"https://doi.org/10.1002/adma.202414365","url":null,"abstract":"Radiofrequency ablation (RFA), a critical therapy for hepatocellular carcinoma (HCC), carries a significant risk of recurrence and metastasis, particularly owing to mechanisms involving immune evasion and antigen downregulation via epigenetic modifications. This study introduces a “nano‐epidrug” named MFMP. MFMP, which is composed of hollow mesoporous manganese dioxide (MnO2) nanoparticles, FIDAS‐5 as an MAT2A inhibitor, macrophage membrane, and anti‐PD‐L1 (aPD‐L1), targets HCC cells. By selectively binding to these cells, MFMP initially reverses immune suppression via PD‐L1 inhibition. After endocytosis, MFMP disassembles in the tumor microenvironment, releasing FIDAS‐5 and Mn2+. FIDAS‐5 prevents cGAS methylation, whereas Mn2+ aids STING pathway restoration. In addition, FIDAS‐5 reduces m6A RNA modification, suppressing EGFR expression. These changes enhance HCC antigenicity to promote cytotoxic T cell recognition and cytotoxic killing. Furthermore, MFMP mediates immunogenic cell death in HCC by synergizing with RFA through cGAS DNA demethylation, EGFR mRNA demethylation, and TBK1 protein phosphorylation, thereby inhibiting recurrence and metastasis and enhancing immune memory. Thus, MFMP is a potential adjunctive therapy requiring clinical validation.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"16 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving Oxygen‐Redox‐Active Layered Oxide Cathodes for Sodium‐Ion Batteries Through Crystal Facet Modulation and Fluorinated Interfacial Engineering 通过晶面调制和氟化界面工程改善钠离子电池的氧氧化还原活性层状氧化物阴极

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2024-11-16 DOI: 10.1002/adma.202410575

Yiran Sun, Junying Weng, Pengfei Zhou, Wenyong Yuan, Yihao Pan, Xiaozhong Wu, Jin Zhou, Fangyi Cheng

{"title":"Improving Oxygen‐Redox‐Active Layered Oxide Cathodes for Sodium‐Ion Batteries Through Crystal Facet Modulation and Fluorinated Interfacial Engineering","authors":"Yiran Sun, Junying Weng, Pengfei Zhou, Wenyong Yuan, Yihao Pan, Xiaozhong Wu, Jin Zhou, Fangyi Cheng","doi":"10.1002/adma.202410575","DOIUrl":"https://doi.org/10.1002/adma.202410575","url":null,"abstract":"Layered oxides with active oxygen redox are attractive cathode materials for sodium‐ion batteries (SIBs) due to high capacity but suffer from rapid capacity/voltage deterioration and sluggish reaction kinetics stemming from lattice oxygen release, interfacial side reactions, and structural reconstruction. Herein, a synergistic strategy of crystal‐facet modulation and fluorinated interfacial engineering is proposed to achieve high capacity, superior rate capability, and long cycle stability in Na0.67Li0.24Mn0.76O2. The synthesized single‐crystal Na0.67Li0.24Mn0.76O2 (NLMO{010}) featuring increased {010} active facet exposure exhibits faster anionic redox kinetics and delivers a high capacity (272.4 mAh g−1 at 10 mA g−1) with superior energy density (713.9 Wh kg−1) and rate performance (116.4 mAh g−1 at 1 A g−1). Moreover, by incorporating N‐Fluorobenzenesulfonimide (NFBS) as electrolyte additive, the NLMO{010} cathode retains 84.6% capacity after 400 cycles at 500 mA g−1 with alleviated voltage fade (0.27 mV per cycle). Combined in situ analysis and theoretical calculations unveil dual functionality of NFBS, which results in thin yet durable fluorinated interfaces on the NLMO{010} cathode and hard carbon anode and scavenges highly reactive oxygen species. The results indicate the importance of fast‐ion‐transfer facet engineering and fluorinated electrolyte formulation to enhance oxygen redox‐active cathode materials for high‐energy‐density SIBs.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"12 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Crystallographic Reorientation Induced by Gradient Solid‐Electrolyte Interphase for Highly Stable Zinc Anode 梯度固体-电解质互相诱导的晶体重新定向，实现高稳定性锌阳极

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2024-11-16 DOI: 10.1002/adma.202412667

Ming Zhao, Yanqun Lv, Jun Qi, Yong Zhang, Yadong Du, Qi Yang, Yunkai Xu, Jieshan Qiu, Jun Lu, Shimou Chen

{"title":"Crystallographic Reorientation Induced by Gradient Solid‐Electrolyte Interphase for Highly Stable Zinc Anode","authors":"Ming Zhao, Yanqun Lv, Jun Qi, Yong Zhang, Yadong Du, Qi Yang, Yunkai Xu, Jieshan Qiu, Jun Lu, Shimou Chen","doi":"10.1002/adma.202412667","DOIUrl":"https://doi.org/10.1002/adma.202412667","url":null,"abstract":"Oriented zinc (Zn) electrodeposition is critical for the long‐term performance of aqueous Zn metal batteries. However, the intricate interfacial reactions between the Zn anode and electrolytes hinder a comprehensive understanding of Zn metal deposition. Here, the reaction pathways of Zn deposition and report the preferential formation of Zn single‐crystalline nuclei followed by dense Zn(002) deposition is elucidated, which is induced by a gradient solid‐electrolyte interphase (SEI). The gradient SEI composed of abundant B‐O and C species facilitates faster Zn2+ nucleation rate and smaller nucleus size, promoting the formation of Zn single‐crystalline nuclei. Additionally, the homogeneity and mechanical stability of SEI ensure the crystallographic reorientation of Zn anodes from Zn(101) to (002) planes, efficiently inhibiting dendrite growth and metal corrosion during the Zn2+ stripping/plating process. These advantages significantly enhance the stability of the Zn anode, as demonstrated by the prolonged cycling lifespan of symmetric Zn batteries and exceptional reversibility (>99.5%) over 5000 cycles in Zn//Cu asymmetric batteries. Notably, this strategy also enables the stable operation of anode‐free Zn//I2 batteries with a long lifespan of 3000 cycles. This work advances the understanding of Zn electrochemical behaviors, encompassing Zn nucleation, growth, and Zn2+ stripping/plating.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"247 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

All-In-One Additive Enabled Efficient and Stable Narrow-Bandgap Perovskites for Monolithic All-Perovskite Tandem Solar Cells 一体化添加剂实现高效稳定的窄带隙过氧化物，用于单片全过氧化物串联太阳能电池

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2024-11-16 DOI: 10.1002/adma.202411677

Deng Wang, Mingqian Chen, Xia Lei, Yunfan Wang, Yuqi Bao, Xiaofeng Huang, Peide Zhu, Jie Zeng, Xingzhu Wang, SaiWing Tsang, Fengzhu Li, Baomin Xu, Alex K.-Y. Jen

{"title":"All-In-One Additive Enabled Efficient and Stable Narrow-Bandgap Perovskites for Monolithic All-Perovskite Tandem Solar Cells","authors":"Deng Wang, Mingqian Chen, Xia Lei, Yunfan Wang, Yuqi Bao, Xiaofeng Huang, Peide Zhu, Jie Zeng, Xingzhu Wang, SaiWing Tsang, Fengzhu Li, Baomin Xu, Alex K.-Y. Jen","doi":"10.1002/adma.202411677","DOIUrl":"https://doi.org/10.1002/adma.202411677","url":null,"abstract":"Hybrid tin-lead (Sn-Pb) perovskites have garnered increasing attention due to their crucial role in all-perovskite tandem cells for surpassing the efficiency limit of single-junction solar cells. However, the easy oxidation of Sn2+ and fast crystallization of Sn-based perovskite present significant challenges for achieving high-quality hybrid Sn-Pb perovskite films, thereby limiting the device's performance and stability. Herein, an all-in-one additive, 2-amino-3-mercaptopropanoic acid hydrochloride (AMPH) is proposed, which can function as a reducing agent to suppress the formation of Sn4+ throughout the film preparation. Furthermore, the strong binding between AMPH and Sn-based precursor significantly slows down the crystallization process, resulting in a high-quality film with enhanced crystallinity. The remaining AMPH and its oxidation products within the film contribute to improves oxidation resistance and a substantial reduction in defect density, specifically Sn vacancies. Benefiting from the multifunctionalities of AMPH, a power conversion efficiency (PCE) of 23.07% is achieved for single-junction narrow-bandgap perovskite solar cells. The best-performing monolithic all-perovskite tandem cell also exhibits a PCE of 28.73% (certified 27.83%), which is among the highest efficiency reported yet. The tandem devices can also retain over 85% of their initial efficiencies after 500 hours of continuous operation at the maximum power point under one-sun illumination.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"17 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Organic Nonvolatile 2T Memory Cell Employing a NOT-Gate-Like Architecture Toward Binary Output Level With Enhanced Noise Tolerance 采用类 NOT 栅极架构的有机非易失性 2T 存储单元，可实现二进制输出电平并提高噪声容限

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2024-11-16 DOI: 10.1002/adma.202412255

Qiang Zhao, Hanlin Wang, Zhenjie Ni, Jie Liu, Jie Li, Fangxu Yang, Liqiang Li, Lang Jiang, Yonggang Zhen, Huanli Dong, Wenping Hu

{"title":"Organic Nonvolatile 2T Memory Cell Employing a NOT-Gate-Like Architecture Toward Binary Output Level With Enhanced Noise Tolerance","authors":"Qiang Zhao, Hanlin Wang, Zhenjie Ni, Jie Liu, Jie Li, Fangxu Yang, Liqiang Li, Lang Jiang, Yonggang Zhen, Huanli Dong, Wenping Hu","doi":"10.1002/adma.202412255","DOIUrl":"https://doi.org/10.1002/adma.202412255","url":null,"abstract":"Organic nonvolatile memory has been considered a low-cost memory technology for flexible electronics and Internet-of-things (IoT). However, a major concern is the nonuniformity of memory units, which is primarily caused by random grain boundaries, interface defects, and charge traps, making it difficult to develop high-density reliable memory arrays. This nonuniformity problem would induce read error, which is directly caused by the narrow distribution margin of memory states and low noise tolerance in conventional organic memory cells. To break this limitation, a novel 2T memory cell employing a NOT-gate-like architecture achieving self-enhancing noise tolerance is presented. This unique cell consists of a pair of commonly-gated memory transistors with contradictory “write-and-erase” features. It functions as a voltage divider, producing a well-distinguished binary voltage output capability. The concept and design model of this brand-new 2T memory cell is thoroughly discussed. It is originally characterized by noise-tolerant memory cells irrespective of device nonuniformity. The noise tolerance range of this 2T memory cell is also investigated. The binary voltage-readable memory state with a large noise tolerance range is obtained. Moreover, the conceptual design of the 1T2T FeRAM cell is further developed for low-cost voltage-readable memory technology in wearable electronic applications.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"48 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stable Surface Contact with Tailored Alkylamine Pyridine Derivatives for High‐Performance Inverted Perovskite Solar Cells 定制烷基胺吡啶衍生物与高性能反相包晶石太阳能电池的稳定表面接触

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2024-11-16 DOI: 10.1002/adma.202415100

Sanwan Liu, Zhenxing Sun, Xia Lei, Tianyin Miao, Qisen Zhou, Rui Chen, Jianan Wang, Fumeng Ren, Yongyan Pan, Yong Cai, Zhengtian Tan, Wenguang Liu, Xiaoxuan Liu, Jingbai Li, Yong Zhang, Baomin Xu, Zonghao Liu, Wei Chen

{"title":"Stable Surface Contact with Tailored Alkylamine Pyridine Derivatives for High‐Performance Inverted Perovskite Solar Cells","authors":"Sanwan Liu, Zhenxing Sun, Xia Lei, Tianyin Miao, Qisen Zhou, Rui Chen, Jianan Wang, Fumeng Ren, Yongyan Pan, Yong Cai, Zhengtian Tan, Wenguang Liu, Xiaoxuan Liu, Jingbai Li, Yong Zhang, Baomin Xu, Zonghao Liu, Wei Chen","doi":"10.1002/adma.202415100","DOIUrl":"https://doi.org/10.1002/adma.202415100","url":null,"abstract":"Formamidinium‐cesium lead triiodide (FA1‐xCsxPbI3) perovskite holds great promise for perovskite solar cells (PSCs) with both high efficiency and stability. However, the defective perovskite surfaces induced by defects and residual tensile strain largely limit the photovoltaic performance of the corresponding devices. Here, the passivation capability of alkylamine‐modified pyridine derivatives for the surface defects of FA1‐xCsxPbI3 perovskite is systematically studied. Among the studied surface passivators, 3‐(2‐aminoethyl)pyridine (3‐PyEA) with the suitable size is demonstrated to be the most effective in reducing surface iodine impurities and defects (VI and I2) through its strong coordination with Npyridine. Additionally, the tail amino group (─NH2) from 3‐PyEA can react with FA+ cations to reduce the surface roughness of perovskite films, and the reaction products can also passivate FA vacancies (VFA), and further strengthen their binding interaction to perovskite surfaces. These merits lead to suppressed nonradiative recombination loss, the release of residual tensile stress for the perovskite films, and a favorable energy‐level alignment at the perovskite/[6,6]‐phenyl‐C61‐butyric acid methyl ester interface. Consequently, the resulting inverted FA1‐xCsxPbI3 PSCs obtain an impressive power conversion efficiency (PCE) of 25.65% (certified 25.45%, certified steady‐state efficiency 25.06%), along with retaining 96.5% of the initial PCE after 1800 h of 1‐sun operation at 55 °C in air.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"6 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced Stability and Brightness through Co‐Substitution: Promoting Plant Growth with Green‐Excited Deep Red Phosphor Ca1‐zSrzLi1‐xMg2xAl3‐xN4:yEu2+ 通过共替代增强稳定性和亮度：利用绿激发深红荧光粉 Ca1-zSrzLi1-xMg2xAl3-xN4:yEu2+ 促进植物生长

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2024-11-16 DOI: 10.1002/adma.202414578

Pengpeng Wang, Yuhua Wang, Zebin Li, Haoyang Wang, Takatoshi Seto

{"title":"Enhanced Stability and Brightness through Co‐Substitution: Promoting Plant Growth with Green‐Excited Deep Red Phosphor Ca1‐zSrzLi1‐xMg2xAl3‐xN4:yEu2+","authors":"Pengpeng Wang, Yuhua Wang, Zebin Li, Haoyang Wang, Takatoshi Seto","doi":"10.1002/adma.202414578","DOIUrl":"https://doi.org/10.1002/adma.202414578","url":null,"abstract":"The research utilized a strategy of chemical unit co‐substitution, successfully developing a novel blue‐green to green excited, deep red‐emitting phosphor, Ca1‐zSrzLi1‐xMg2xAl3‐xN4:yEu2+ (CLA‐2xM‐zS:yEu, 0≤x≤0.8, 0.003≤y≤0.01, 0≤z≤1), through the replacement of [Li−Al]4+ by [Mg−Mg]4+. This phosphor uniquely converts unusable green light to growth‐enhancing deep red, optimizing it for outdoor agriculture. Doping with Sr creates traps, causing a redshift in emission peaks, as confirmed by 7Li nuclear magnetic resonance (NMR) spectra, indicating Li presence and lattice changes. Ca0.2Sr0.8Li0.5MgAl2.5N4:0.005Eu2+ (CLAM‐0.8S) phosphor maintained high luminescence intensity under extreme conditions of 85 °C/85% RH, demonstrating excellent photoluminescence performance and chemical stability, compared with conventional SrLi0.5MgAl2.5N4:0.005Eu2+ (SLMA) and SrLiAl3N4:0.005Eu2+(SLA). Experimental results surprised that the unique Ca0.2Sr0.8Li0.8Mg0.4Al2.8N4:0.005Eu2+ (CLA‐0.4M‐0.8S) prepared light‐converting film, which is mainly excited by green light, demonstrated a 20% increase in optical density of Chlorella compared to the PP film and a remarkable 97.5% increase compared to the control group without any film. These findings suggest that this film has significant potential for applications in outdoor agriculture and other fields.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"25 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanomaterial-Mediated Reprogramming of Macrophages to Inhibit Refractory Muscle Fibrosis 纳米材料介导的巨噬细胞重编程抑制难治性肌肉纤维化

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2024-11-16 DOI: 10.1002/adma.202410368

Xu Cheng, Hao Sui, Fangman Chen, Chenghao Li, Meijun Du, Shiming Zhang, Jiali Chen, Jinfeng Dou, Yixuan Huang, Xiaochun Xie, Chuanxu Cheng, Renjie Yang, Chao Yang, Bing Shi, Dan Shao, Kam W. Leong, Hanyao Huang

{"title":"Nanomaterial-Mediated Reprogramming of Macrophages to Inhibit Refractory Muscle Fibrosis","authors":"Xu Cheng, Hao Sui, Fangman Chen, Chenghao Li, Meijun Du, Shiming Zhang, Jiali Chen, Jinfeng Dou, Yixuan Huang, Xiaochun Xie, Chuanxu Cheng, Renjie Yang, Chao Yang, Bing Shi, Dan Shao, Kam W. Leong, Hanyao Huang","doi":"10.1002/adma.202410368","DOIUrl":"https://doi.org/10.1002/adma.202410368","url":null,"abstract":"Orofacial muscles are particularly prone to refractory fibrosis after injury, leading to a negative effect on the patient's quality of life and limited therapeutic options. Gaining insights into innate inflammatory response-fibrogenesis homeostasis can aid in the development of new therapeutic strategies for muscle fibrosis. In this study, the crucial role of macrophages is identified in the regulation of orofacial muscle fibrogenesis after injury. Hypothesizing that orchestrating macrophage polarization and functions will be beneficial for fibrosis treatment, nanomaterials are engineered with polyethylenimine functionalization to regulate the macrophage phenotype by capturing negatively charged cell-free nucleic acids (cfNAs). This cationic nanomaterial reduces macrophage-related inflammation in vitr and demonstrates excellent efficacy in preventing orofacial muscle fibrosis in vivo. Single-cell RNA sequencing reveals that the cationic nanomaterial reduces the proportion of profibrotic Gal3+ macrophages through the cfNA-mediated TLR7/9-NF-κB signaling pathway, resulting in a shift in profibrotic fibro-adipogenic progenitors (FAPs) from the matrix-producing Fabp4+ subcluster to the matrix-degrading Igf1+ subcluster. The study highlights a strategy to target innate inflammatory response-fibrogenesis homeostasis and suggests that cationic nanomaterials can be exploited for treating refractory fibrosis.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"12 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Macroscale Superlubrication Achieved with Shear-Thinning Semisolid Lubricants 利用剪切稀化半固体润滑剂实现宏观超润滑

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2024-11-16 DOI: 10.1002/adma.202412257

Liucheng Wang, Liqiang Zhang, Runhao Zheng, Changhe Du, Tongtong Yu, Kunpeng Li, Weifeng Bu, Daoai Wang

{"title":"Macroscale Superlubrication Achieved with Shear-Thinning Semisolid Lubricants","authors":"Liucheng Wang, Liqiang Zhang, Runhao Zheng, Changhe Du, Tongtong Yu, Kunpeng Li, Weifeng Bu, Daoai Wang","doi":"10.1002/adma.202412257","DOIUrl":"https://doi.org/10.1002/adma.202412257","url":null,"abstract":"Macrosuperlubric materials are pivotal for reducing friction and wear in engineering applications. However, current solid superlubricants require intricate fabrication and specific conditions (e.g., vacuum or inert atmospheres), while liquid superlubricants are prone to creep, leakage, and corrosion. Here, a novel semisolid subnanometer nanowire (SNW) superlubrication material based on the shear-thinning effect is introduced to overcome these challenges. The SNWs achieve an exceptionally low friction coefficient (0.008–0.009) with silicon nitride (Si3N4) and polytetrafluoroethylene (PTFE) tribo-pairs, demonstrating a brief running-in period (≈39 s) and stable superlubrication over extended friction (12 h, >120 000 cycles). The combination of the shear-thinning network structure mechanism, the adsorption membrane mechanism, and hydrodynamic effects provides a synergistic effect, playing a crucial role in achieving superlubricity. Additionally, SNWs can be combined with various base oils to create semisolid gel lubricants with superlubricating properties. This innovative approach addresses the limitations of current superlubrication systems and introduces a new category of semisolid gel lubricants, significantly expanding the applications of superlubrication materials.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"94 1 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding, Mimicking, and Mitigating Radiolytic Damage to Polymers in Liquid Phase Transmission Electron Microscopy 在液相透射电子显微镜中了解、模拟和减轻聚合物的放射性损伤

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2024-11-16 DOI: 10.1002/adma.202402987

Hanglong Wu, Hongyu Sun, Roy A. J. F. Oerlemans, Siyu Li, Jingxin Shao, Jianhong Wang, Rick R. M. Joosten, Xianwen Lou, Yingtong Luo, Hongkui Zheng, Loai K. E. A. Abdelmohsen, H. Hugo Pérez Garza, Jan C. M. van Hest, Heiner Friedrich

{"title":"Understanding, Mimicking, and Mitigating Radiolytic Damage to Polymers in Liquid Phase Transmission Electron Microscopy","authors":"Hanglong Wu, Hongyu Sun, Roy A. J. F. Oerlemans, Siyu Li, Jingxin Shao, Jianhong Wang, Rick R. M. Joosten, Xianwen Lou, Yingtong Luo, Hongkui Zheng, Loai K. E. A. Abdelmohsen, H. Hugo Pérez Garza, Jan C. M. van Hest, Heiner Friedrich","doi":"10.1002/adma.202402987","DOIUrl":"https://doi.org/10.1002/adma.202402987","url":null,"abstract":"Advances in liquid phase transmission electron microscopy (LP-TEM) have enabled the monitoring of polymer dynamics in solution at the nanoscale, but radiolytic damage during LP-TEM imaging limits its routine use in polymer science. This study focuses on understanding, mimicking, and mitigating radiolytic damage observed in functional polymers in LP-TEM. It is quantitatively demonstrated how polymer damage occurs across all conceivable (LP-)TEM environments, and the key characteristics and differences between polymer degradation in water vapor and liquid water are elucidated. Importantly, it is shown that the hydroxyl radical-rich environment in LP-TEM can be approximated by UV light irradiation in the presence of hydrogen peroxide, allowing the use of bulk techniques to probe damage at the polymer chain level. Finally, the protective effects of commonly used hydroxyl radical scavengers are compared, revealing that the effectiveness of graphene's protection is distance-dependent. The work provides detailed methodological guidance and establishes a baseline for polymer degradation in LP-TEM, paving the way for future research on nanoscale tracking of shape transitions and drug encapsulation of polymer assemblies in solution.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"98 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0