Yinan Li, Xiu Huang, Qingqing Qiao, Yingying Li, Xu Han, Caihong Chen, Yang Chen, Shuang Guo, Yang Zhang, Wenqing Gao, Huijuan Liu, Tao Sun
{"title":"Suppression of Sepsis Cytokine Storm by Escherichia Coli Cell Wall-Derived Carbon Dots (Adv. Mater. 12/2025)","authors":"Yinan Li, Xiu Huang, Qingqing Qiao, Yingying Li, Xu Han, Caihong Chen, Yang Chen, Shuang Guo, Yang Zhang, Wenqing Gao, Huijuan Liu, Tao Sun","doi":"10.1002/adma.202570100","DOIUrl":"https://doi.org/10.1002/adma.202570100","url":null,"abstract":"<p><b>Suppression of Sepsis Cytokine Storm</b></p><p><i>Escherichia coli</i> can be transformed into therapeutic nanodrugs through high-temperature treatment, alluding to the concept of the ‘phoenix bathing in fire, attaining nirvana, and being reborn, transforming defilement into purity.’ This suggests that drugs for combating infectious diseases can be derived from the transformation of pathogens themselves, offering a versatile and promising approach for drug development with broad potential applications. More details can be found in article number 2414237 by Yang Zhang, Wenqing Gao, Huijuan Liu, Tao Sun, and co-workers.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"37 12","pages":""},"PeriodicalIF":27.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202570100","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143698873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nan Li, Fei Zhan, Minghui Guo, Xiaohong Yuan, Xueqing Chen, Yuqing Li, Guangcheng Zhang, Lei Wang, Jing Liu
{"title":"Fingertip-Inspired Spatially Anisotropic Inductive Liquid Metal Sensors with Ultra-Wide Range, High Linearity and Exceptional Stability","authors":"Nan Li, Fei Zhan, Minghui Guo, Xiaohong Yuan, Xueqing Chen, Yuqing Li, Guangcheng Zhang, Lei Wang, Jing Liu","doi":"10.1002/adma.202419524","DOIUrl":"https://doi.org/10.1002/adma.202419524","url":null,"abstract":"The advancement of robotic behavior and intelligence has led to an urgent demand for improving their sensitivity and interactive capabilities, which presents challenges in achieving multidimensional, wide-ranging, and reliable tactile sensing. Here an anisotropic inductive liquid metal sensor (AI-LMS) is introduced inspired by the human fingertip, which inherently possesses the capability to detect spatially multi-axis pressure with a wide sensing range, exceptional linearity, and signal stability. Additionally, it can detect very small pressures and responds swiftly to prescribed forces. Compared to resistive signals, inductive signals offer significant advantages. Further, integrated with a deep neural network model, the AI-LMS can decouple multi-axis pressures acting simultaneously upon it. Notably, the sensing range of Ecoflex and PDMS-based AI-LMS can be expanded by a factor of 4 and 9.5, respectively. For practical illustrations, a high-precision surface scanning reconstruction system is developed capable of capturing intricate details of 3D surface profiles. The utilization of biomimetic AI-LMS as robotic fingertips enables real-time discrimination of diverse delicate grasping behaviors across different fingers. The innovations and unique features in sensing mechanisms and structural design are expected to bring transformative changes and find extensive applications in the field of soft robotics.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"33 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143703095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiajia Tang, Jie Zhang, Yang Li, Yongzhi Hu, Doudou He, Hao Ni, Jiulou Zhang, Feiyun Wu, Yuxia Tang, Shouju Wang
{"title":"Interpretable Radiomics Model Predicts Nanomedicine Tumor Accumulation Using Routine Medical Imaging (Adv. Mater. 12/2025)","authors":"Jiajia Tang, Jie Zhang, Yang Li, Yongzhi Hu, Doudou He, Hao Ni, Jiulou Zhang, Feiyun Wu, Yuxia Tang, Shouju Wang","doi":"10.1002/adma.202570098","DOIUrl":"https://doi.org/10.1002/adma.202570098","url":null,"abstract":"<p><b>Nanomedicine Accumulation</b></p><p>Accurate prediction of nanomedicine accumulation is crucial for guiding patient stratification and optimizing treatment strategies in precision medicine. In article number 2416696, Shouju Wang and colleagues present an interpretable radiomics model capable of predicting nanomedicine tumor accumulation using routine medical imaging, achieving an impressive accuracy of 0.851. This study demonstrates the potential of noninvasive imaging for patient stratification and the precise tailoring of nanomedicine therapies, paving the way for more personalized and effective cancer treatment.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"37 12","pages":""},"PeriodicalIF":27.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202570098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Strain Relaxation Modulation for Printing High-performance Flexible Pseudo-Planar Heterojunction Organic Solar Cells","authors":"Rui Gong, Qing Yan, Zhi Xing, Hanlin Wang, Licheng Tan, Xiangchuan Meng, Xiaotian Hu, Yiwang Chen","doi":"10.1002/adma.202501033","DOIUrl":"https://doi.org/10.1002/adma.202501033","url":null,"abstract":"The rational toughening of photosensitive films is crucial for the development of robust and flexible organic solar cells (F-OSCs), which are always influenced by mechanical strain and thermodynamic relaxation within the films. Nevertheless, the potential determinants of these properties and quantitative metrics modulating the overall performance of flexible devices have not been thoroughly defined. Herein, a fine-grain strengthening strategy is demonstrated for mitigating the excessive aggregation or crystallization in small-molecule acceptor films, the secondary thermal relaxation of side chains in polyethylene oxide (PEO) local motion restricts the free fluctuation volume through hydrogen-bonding interactions, thereby suppressing the non-ideal thermodynamic behavior and residual-enriched state. These contribute to an increase in yield strength and a reduction in microcracks while enhancing the fracture energy at the donor/acceptor interface. Finally, the optimal F-OSCs demonstrate champion PCEs of 19.12% (0.04 cm<sup>2</sup>) and 16.92% (1.00 cm<sup>2</sup>), and maintain 80% of their initial efficiency after heating at 85 °C for 2600 h. Besides, the flexibility and mechanical robustness of devices are also optimized, the elastic modulus and stiffness are decreased by 50.68% and 5.71%. This work provides interesting references for the synergistic enhancement of efficiency, mechanical and environmental stability in flexible organic photovoltaics.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"30 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143713588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhiwei Xie, Ke Jiang, Shanli Zhang, Zhongqiang Wang, Xuanyu Shan, Bingxiang Wang, Jianwei Ben, Mingrui Liu, Shunpeng Lv, Yang Chen, Yuping Jia, Xiaojuan Sun, Dabing Li
{"title":"Ultraviolet Optoelectronic Synapse Based on AlScN/p-i-n GaN Heterojunction for Advanced Artificial Vision Systems","authors":"Zhiwei Xie, Ke Jiang, Shanli Zhang, Zhongqiang Wang, Xuanyu Shan, Bingxiang Wang, Jianwei Ben, Mingrui Liu, Shunpeng Lv, Yang Chen, Yuping Jia, Xiaojuan Sun, Dabing Li","doi":"10.1002/adma.202419316","DOIUrl":"https://doi.org/10.1002/adma.202419316","url":null,"abstract":"Ferroelectric materials represent a frontier in semiconductor research, offering the potential for novel optoelectronics. AlScN material is a kind of outstanding ferroelectric semiconductor with strong residual polarization, high Curie temperature, and mainstream semiconductor fabrication compatibility. However, it is challenging to realize multi-state optical responders due to their limited light sensitivity. Here, a two-terminal AlScN/p-i-n GaN heterojunction ultraviolet optoelectronic synapse is fabricated, overcoming this limitation by leveraging hole capture at the AlScN/p-GaN hetero-interface for multi-state modulation. The novel structure maintains excellent memristor characteristics based on the ferroelectric of AlScN, realizing an on/off ratio of 9.36 × 10<sup>5</sup>. More importantly, the device can mimic synaptic characteristics essential for artificial vision systems, achieving an image recognition accuracy of 93.7% with a weight evolution nonlinearity of 0.26. This approach not only extends the applications of AlScN in optoelectronics but also paves the way for advanced artificial vision systems with image preprocessing and recognition capabilities. The findings provide a step forward in the development of non-volatile memories with potential for on-chip sensing and computing.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"28 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143703037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrey Sokolov, Jaideep Katuri, Juan J. de Pablo, Alexey Snezhko
{"title":"Synthetic Active Liquid Crystals Powered by Acoustic Waves","authors":"Andrey Sokolov, Jaideep Katuri, Juan J. de Pablo, Alexey Snezhko","doi":"10.1002/adma.202418846","DOIUrl":"https://doi.org/10.1002/adma.202418846","url":null,"abstract":"Active nematic materials combine orientational order with activity at the microscopic level. Current experimental realizations of active nematics include vibrating elongated particles, cell layers, suspensions of elongated bacteria, and a mixture of bio-filaments with molecular motors. The majority of active nematics are of biological origin. The realization of a fully synthetic active liquid crystal comprised of a lyotropic chromonic liquid crystal energized by ultrasonic waves, is reported. This synthetic active liquid crystal is free from biological degradation and variability, exhibits phenomenology associated with active nematics, and enables precise and rapid activity control over a significantly extended range. It is demonstrated that the energy of the acoustic field is converted into microscopic extensile stresses disrupting long-range nematic order and giving rise to an undulation instability and proliferation of topological defects. The emergence of unconventional free-standing persistent vortices in the nematic director field at high activity levels is revealed. The results provide a foundation for the design of externally energized active liquid crystals with stable material properties and tunable topological defect dynamics crucial for the realization of reconfigurable microfluidic systems.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"29 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143703090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Fusco, Arianna Gazzi, Linda Giro, Roman B. Schefer, Sènan Mickael D'Almeida, Roberta Cagliani, Martina Zoccheddu, Recep Uyar, Ömur Besbinar, Doğantan Çelik, Acelya Yilmazer, Denise M. Mitrano, Marco Orecchioni, Lucia Gemma Delogu
{"title":"Nanoplastics: Immune Impact, Detection, and Internalization after Human Blood Exposure by Single-Cell Mass Cytometry (Adv. Mater. 12/2025)","authors":"Laura Fusco, Arianna Gazzi, Linda Giro, Roman B. Schefer, Sènan Mickael D'Almeida, Roberta Cagliani, Martina Zoccheddu, Recep Uyar, Ömur Besbinar, Doğantan Çelik, Acelya Yilmazer, Denise M. Mitrano, Marco Orecchioni, Lucia Gemma Delogu","doi":"10.1002/adma.202570099","DOIUrl":"https://doi.org/10.1002/adma.202570099","url":null,"abstract":"<p><b>Nanoplastics</b></p><p>In article number 2413413, Acelya Yilmazer, Marco Orecchioni, Lucia Gemma Delogu, and co-workers explore the interaction of nanoplastics with human immune cells, using advanced single-cell mass cytometry. Findings reveal nanoplastics uptake on several immune cell subpopulations, affecting cell viability and functionality. Art by the team of INMYWORK Studio.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"37 12","pages":""},"PeriodicalIF":27.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202570099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iman M. Imani, Hyun Soo Kim, Minhyuk Lee, Seung-Bum Kim, So-Min Song, Dong-Gyu Lee, Joon-Ha Hwang, Jeyeon Lee, In-Yong Suh, Sang-Woo Kim, Jun Chen, Heemin Kang, Donghee Son, Jeong Min Baik, Sunghoon Hur, Hyun-Cheol Song
{"title":"A Body Conformal Ultrasound Receiver for Efficient and Stable Wireless Power Transfer in Deep Percutaneous Charging","authors":"Iman M. Imani, Hyun Soo Kim, Minhyuk Lee, Seung-Bum Kim, So-Min Song, Dong-Gyu Lee, Joon-Ha Hwang, Jeyeon Lee, In-Yong Suh, Sang-Woo Kim, Jun Chen, Heemin Kang, Donghee Son, Jeong Min Baik, Sunghoon Hur, Hyun-Cheol Song","doi":"10.1002/adma.202419264","DOIUrl":"https://doi.org/10.1002/adma.202419264","url":null,"abstract":"Wireless powering of rechargeable-implantable medical devices presents a challenge in developing reliable wireless energy transfer systems that meet medical safety and standards. Ultrasound-driven triboelectric nanogenerators (US-TENG) are investigated for various medical applications, including noninvasive percutaneous wireless battery powering to reduce the need for multiple surgeries for battery replacement. However, these devices often suffer from inefficiency due to limited output performance and rigidity. To address this issue, a dielectric-ferroelectric boosted US-TENG (US-TENG<sub>DF-B</sub>) capable of producing a high output charge with low-intensity ultrasound and a long probe distance is developed, comparatively. The feasibility and output stability of this deformable and augmented device is confirmed under various bending conditions, making it suitable for use in the body's curved positions or with electronic implants. The device achieved an output of ≈26 V and ≈6.7 mW output for remote charging of a rechargeable battery at a 35 mm distance. These results demonstrate the effectiveness of the output-augmented US-TENG for deep short-term wireless charging of implantable electronics with flexing conditions in curved devices such as future total artificial hearts.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"99 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143703093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiachen Liang, Xinyue Huang, Kaiqi Qin, Hui Wei, Jiaxin Yang, Bin Liu, Zengjie Fan
{"title":"Implanted Magnetoelectric Bionic Cartilage Hydrogel","authors":"Jiachen Liang, Xinyue Huang, Kaiqi Qin, Hui Wei, Jiaxin Yang, Bin Liu, Zengjie Fan","doi":"10.1002/adma.202415417","DOIUrl":"https://doi.org/10.1002/adma.202415417","url":null,"abstract":"Enhancing defective cartilage repair by creating a bionic cartilage hydrogel supplemented with in situ electromagnetic stimulation, replicating endogenous electromagnetic effects, remains challenging. To achieve this, a unique three-phase solvent system is designed to prepare a magnetoelectric bionic cartilage hydrogel incorporating piezoelectric poly(3-hydroxybutyric acid-3-hydroxyvaleric acid) (PHBV) and magnetostrictive triiron tetraoxide nanoparticles (Fe<sub>3</sub>O<sub>4</sub> NPs) into sodium alginate (SA) hydrogel to form a dual-network, semi-crosslinked chain entanglement structure. The synthesized hydrogel features similar composition, structure, and mechanical properties to natural cartilage. In addition, after the implantation of cartilage, the motion-driven magnetoelectric-coupled cyclic transformation model is triggered by gentle joint forces, initiating a piezoelectric response that leads to magnetoelectric-coupled cyclic transformation. The freely excitable and cyclically enhanced electromagnetic stimulation it can provide, by simulating and amplifying endogenous electromagnetic effects, obtains induced defective cartilage repair efficacy superior to piezoelectric or magnetic stimulation alone.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"13 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143703092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paula Kirya, Aida Mestre-Farrera, Jing Yang, Lisa V. Poulikakos
{"title":"Leveraging Optical Anisotropy of the Morpho Butterfly Wing for Quantitative, Stain-Free, and Contact-Free Assessment of Biological Tissue Microstructures (Adv. Mater. 12/2025)","authors":"Paula Kirya, Aida Mestre-Farrera, Jing Yang, Lisa V. Poulikakos","doi":"10.1002/adma.202570094","DOIUrl":"https://doi.org/10.1002/adma.202570094","url":null,"abstract":"<p><b>Biological Tissue Microstructures</b></p><p>The Morpho butterfly wing is a natural photonic crystal that interacts selectively with polarized light. Lisa V. Poulikakos and co-workers interface the Morpho wing with breast cancer tissue sections and illuminate the system with polarized light for quantitative, contact- and stain-free assessment of tissue microstructures. This imaging approach enables improved understanding of the role of tissue microstructure in the origin and progression of disease. More details can be found in article number 2407728.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"37 12","pages":""},"PeriodicalIF":27.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202570094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143698871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}