Advanced Materials最新文献_第9页

Cu2O/CuVO3 Nano-Heterojunction as a Highly Active Therapeutic Catalyst for Aggravating Redox Dyshomeostasis of Neoplastic Cells Cu2O/CuVO3纳米异质结作为肿瘤细胞氧化还原失衡的高活性治疗催化剂

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-06-01 DOI: 10.1002/adma.202502407

Weisheng Zhu, Junjie Wu, Yuejun Kang, Peng Xue

{"title":"Cu2O/CuVO3 Nano-Heterojunction as a Highly Active Therapeutic Catalyst for Aggravating Redox Dyshomeostasis of Neoplastic Cells","authors":"Weisheng Zhu, Junjie Wu, Yuejun Kang, Peng Xue","doi":"10.1002/adma.202502407","DOIUrl":"https://doi.org/10.1002/adma.202502407","url":null,"abstract":"Redox dyshomeostasis is both a hallmark and a vulnerability of cancer cells, offering multiple avenues for therapeutic intervention. Herein, a belt-like nano-heterojunction Cu2O/CuVO3 (CVO) is developed as a potential redox dyshomeostasis inducer by exacerbating ROS levels and compromising antioxidant defense without the need of exogenous stimulations. Steady-state analysis reveals that CVO exhibits extraordinary reaction velocity and catalytic efficiency (Vmax = 2.32 µm s−1, Kcat = 0.49 s−1) in the production of hydroxyl radicals (·OH). Likewise, density functional theory (DFT) calculations indicate that the superb charge-transferring properties in the heterojunction structure and unique surface coverage rate of CVO primarily dominate the high-efficient catalytic reactions. Noteworthy, CVO is capable of inducing mitochondria dysfunction by aggravating the cellular redox imbalance, thereby triggering multiple cell death pathways and generating synergistic effects. Transcriptomics analysis outcomes further demonstrate that CVO exerts significant and distinct effects on key biological processes in tumor cells, encompassing but not limited to canonical pathways such as apoptosis, ferroptosis, and cuprotosis. Both in vitro and in vivo studies demonstrate the pronounced tumor-inhibitory efficacy of CVO, which paves a promising pathway for the development of novel nanocatalysts that effectively target cancer through the amplification of redox dyshomeostasis.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"98 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient Artificial T Cell Therapy for Bacterial-Colonized Tumors 有效的人工T细胞治疗细菌定植肿瘤

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-06-01 DOI: 10.1002/adma.202503087

Shiyu Zhang, Han Zhu, Xintao Peng, Yang Zhou, Rentang Huang, Yi-Fan Wang, Shu-Lin Liu, Zhi-Gang Wang

引用次数: 0

Adhesively Bridging Co-Self-Assembled Monolayer and Perovskite Via In Situ Polymerization for Enhanced Stability of Inverted Perovskite Solar Cells 通过原位聚合胶接共自组装单层与钙钛矿增强倒钙钛矿太阳能电池稳定性

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-06-01 DOI: 10.1002/adma.202505745

Xiaowei Xu, Sibo Li, Chengwei Shan, Wenbo Peng, You Chen, Shangzhi Li, Haichen Peng, Tingting Dai, Erjun Zhou, Yang Bai, Longbin Qiu, Pingping Sun, Baomin Xu, Aung Ko Ko Kyaw

{"title":"Adhesively Bridging Co-Self-Assembled Monolayer and Perovskite Via In Situ Polymerization for Enhanced Stability of Inverted Perovskite Solar Cells","authors":"Xiaowei Xu, Sibo Li, Chengwei Shan, Wenbo Peng, You Chen, Shangzhi Li, Haichen Peng, Tingting Dai, Erjun Zhou, Yang Bai, Longbin Qiu, Pingping Sun, Baomin Xu, Aung Ko Ko Kyaw","doi":"10.1002/adma.202505745","DOIUrl":"https://doi.org/10.1002/adma.202505745","url":null,"abstract":"The strategic utilization of self-assembled monolayers (SAMs) significantly advances the interfacial contact and power conversion efficiency (PCE) of inverted perovskite solar cells (IPSCs). However, inadequate adhesion between the SAM and perovskite layer remains a critical challenge, limiting further performance enhancement. Herein, a synergistic interface engineering strategy is introduced that combines a co-assembly approach with in situ polymerization to optimize the buried interface of perovskite film. Specifically, 11-Mercaptoundecylphosphoric acid (MPA) is incorporated into a SAM to form co-SAMs, improving homogeneity and mitigating defects at the NiOx surface. Simultaneously, the ionic liquid (IL) monomer 1-Allyl-3-vinylimidazolium bis((trifluoromethyl)sulfonyl) imide (AVMTF2) is incorporated into the perovskite precursor. The aggregation of ILs cation at the bottom interface facilitates in situ polymerization via sulfhydryl end groups, forming the POL-AVM polymer at the perovskite/SAM interface. This polymer enhances interfacial adhesion, regulates perovskite crystallization, and reinforces structural integrity by strongly anchoring organic cations through multiple hydrogen bonds. As a result, this synergistic strategy achieves a champion PCE of 26.25% (certified 26.04%), along with excellent long-term stability, retaining 95.6% of its initial efficiency after 1000 h of continuous operation under the ISOS-L-2I protocol.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"37 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bio‐Inspired Controllable Liquid Transfer: From Fundamentals in Micro‐Patterning to Applications in Optoelectronics 生物激发的可控液体转移：从微图案的基础到光电子学的应用

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-05-30 DOI: 10.1002/adma.202505085

Zhongyu Shi, Bojie Xu, Yiming Chen, Ji Qin, Zihao Yin, Yan Li, Zheng Xiao, Huanhuan Deng, Mingyan Sun, Ran Sun, Lihong Wang, Yue Sun, Min Zhang, Lili Meng, Huan Liu

{"title":"Bio‐Inspired Controllable Liquid Transfer: From Fundamentals in Micro‐Patterning to Applications in Optoelectronics","authors":"Zhongyu Shi, Bojie Xu, Yiming Chen, Ji Qin, Zihao Yin, Yan Li, Zheng Xiao, Huanhuan Deng, Mingyan Sun, Ran Sun, Lihong Wang, Yue Sun, Min Zhang, Lili Meng, Huan Liu","doi":"10.1002/adma.202505085","DOIUrl":"https://doi.org/10.1002/adma.202505085","url":null,"abstract":"Solution‐processed micro‐patterning is a crucial process for making high‐performance optoelectronic devices, since the carrier transfer behavior is closely related to the uniformity, orientation, and resolution of micro‐patterns. Developing solution processes with good controllability has thus attracted increasing research interest in the last decade. Inspired by Chinese brushes, a fibrous‐guided direct‐writing strategy is recently developed that enables controllable liquid transfer for making micro‐patterns, which is systematically reviewed from viewpoints of both the fundamentals in liquid manipulation and the applications in optoelectronics. First, a model structure of dual‐conical fibers (CFs) is proposed, whose capacity in liquid transfer is featured as the dynamic liquid balance and the uniform liquid film. On the basis, triple‐ and multi‐ CFs are developed for transferring liquid onto the target substrate in a controllable manner, where the tri‐phase contact line can be finely tuned. Thereafter, micro‐patterns with µm‐scale resolution, cm‐scale uniformity, and molecular‐scale orientation can be achieved, as is demonstrated by the as‐prepared ultrasmooth quantum dot films, highly aligned silver nanowires films, and wrinkle‐free reduced graphene oxide films, respectively. The high‐performance optoelectronic devices, including quantum dot light‐emitting diodes, flexible transparent electrodes, and pressure sensors, are demonstrated. Perspectives for solution‐processed micro‐patterning in optoelectronics are also suggested.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"146 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Edge States in 2D A2PbBr4 Hybrid Perovskites Enabled by Local Structural Reorganization 局部结构重组激活二维A2PbBr4杂化钙钛矿的边缘态

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-05-30 DOI: 10.1002/adma.202419606

Zhi‐Gang Li, Xiang Li, Xiao‐Hui Dong, Hai‐Peng Song, Zi‐Ying Li, Xiang Wu, Ilya Kupenko, Michael Hanfland, Konstantin Glazyrin, Jacky Even, Wei Li, Xian‐He Bu

{"title":"Edge States in 2D A2PbBr4 Hybrid Perovskites Enabled by Local Structural Reorganization","authors":"Zhi‐Gang Li, Xiang Li, Xiao‐Hui Dong, Hai‐Peng Song, Zi‐Ying Li, Xiang Wu, Ilya Kupenko, Michael Hanfland, Konstantin Glazyrin, Jacky Even, Wei Li, Xian‐He Bu","doi":"10.1002/adma.202419606","DOIUrl":"https://doi.org/10.1002/adma.202419606","url":null,"abstract":"The edge states (ES) in two‐dimensional (2D) hybrid lead halide perovskites (LHPs) exhibit distinct electronic characteristics, including lower energy and longer lifetimes compared to the interior states (IS). Though the ES of these 2D LHPs show prospect of facilitating photovoltaic and optoelectronic effects, the underlying mechanism remains elusive. Here, the occurrence of ES in a family of 2D A2PbBr4 (A = organic amine cation) LHPs is attributed to the Rashba/Dresselhaus (RD) spin splitting induced by local structural reorganization on the crystal edge. The experimental and theoretical characterizations reveal that the local structure on the crystal edge is significantly strained, which leads to considerable out‐of‐plane distortion of adjacent PbBr6 octahedra, local loss of inversion symmetry and therefore spin‐splitting energy required for the formation of ES. This findings contribute fresh perspectives to the fundamental comprehension of the RD effect, extending the boundaries of spintronics and opening promising pathways for the conceptualization and refinement of devices centered on ES.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"98 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in Biocompatible Metal-Organic Frameworks for Biomedical Applications 生物相容性金属-有机框架在生物医学应用中的研究进展

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-05-30 DOI: 10.1002/adma.202503946

Zhe Li, Minghong He, Yuanbo Wang, Jing Yang, Yuexin He, Xingyu Chen, Weikang Zhang, Hao Wu, Renjie Chai, Bo Wang

引用次数: 0

Electrochemical Cell Designs for Efficient Carbon Dioxide Reduction and Water Electrolysis: Status and Perspectives 高效二氧化碳还原和水电解的电化学电池设计：现状与展望

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-05-30 DOI: 10.1002/adma.202505287

Zhangsen Chen, Lei Zhang, Shuhui Sun, Gaixia Zhang

{"title":"Electrochemical Cell Designs for Efficient Carbon Dioxide Reduction and Water Electrolysis: Status and Perspectives","authors":"Zhangsen Chen, Lei Zhang, Shuhui Sun, Gaixia Zhang","doi":"10.1002/adma.202505287","DOIUrl":"https://doi.org/10.1002/adma.202505287","url":null,"abstract":"Integrating renewable electricity and concentrated CO2 from direct air capture, electrochemical CO2 reduction reactions (eCO2RR) offer a promising pathway for converting CO2 into fuel chemicals, enabling the closure of the carbon loop in a sustainable manner. The clean H2 produced via the hydrogen evolution reaction (HER) during water electrolysis can replace traditional fossil fuels without additional CO2 emissions. Achieving large-scale and high-efficiency eCO2RR and HER requires the development of rational electrolyzer designs, which are crucial for industrial implementation. This review examines recent innovations in system designs for eCO2RR, HER, and the latest advances in in situ cell designs for operando characterization during electrochemical reactions. It focuses on cell improvements in flow patterns, membrane electrode assemblies, and electrolyte engineering to maximize catalytic activities at the industrial level. Besides, the review discusses optimizing counter-anodic reactions to improve the energy efficiency of eCO2RR and water electrolysis, offering insights into the design of catalytic systems with efficient energy utilization. Furthermore, it explores the integration of eCO2RR and HER with other electrochemical systems (e.g., fuel cells), highlighting their potential role in the decarbonization of future industrial processes. Finally, the summary, challenge, and outlook on the industrial-scale eCO2RR and water electrolysis system designs are concluded.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"82 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Self-Replenishable Metabolically Augmented Synbiotic Microspheres Remodel Gut-Bone Homeostasis 自我补充代谢增强合成微球重塑肠-骨稳态

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-05-30 DOI: 10.1002/adma.202500746

Zhijie Chen, Hua Liu, Yi Chen, Yunkai Tang, Yuan Tang, Bruno Sarmento, Chuan He, Zhengwei Cai, Wenguo Cui

{"title":"Self-Replenishable Metabolically Augmented Synbiotic Microspheres Remodel Gut-Bone Homeostasis","authors":"Zhijie Chen, Hua Liu, Yi Chen, Yunkai Tang, Yuan Tang, Bruno Sarmento, Chuan He, Zhengwei Cai, Wenguo Cui","doi":"10.1002/adma.202500746","DOIUrl":"https://doi.org/10.1002/adma.202500746","url":null,"abstract":"Gut microbiota dysbiosis in postmenopausal osteoporosis (PMO) is frequently accompanied by aberrant metabolism and absorption of short-chain fatty acids (SCFAs). However, current oral probiotic therapies neglect the crucial role of probiotic-driven SCFAs metabolism in restoring gut-bone homeostasis. In this study, commencing with the sequencing of fecal samples from clinical patients with PMO, a self-replenishable metabolically augmented synbiotic microsphere (SMASM) is fabricated via a thiol–ene click reaction to restore gut-bone homeostasis using Lactobacillus rhamnosus GG (LGG) as a viable metabolic niche and hyaluronic acid (HA) as a self-replenishable prebiotic substrate. In vitro, the SMASMs exhibit favorable biocompatibility, enhanced resistance to gastric acid, and improved mucosal adhesion for colonization. In vivo, oral administration of SMASMs in ovariectomized mice improves intestinal barrier integrity, mitigates inflammation, and suppresses bone loss, accompanied by alterations in microbial biomarkers and predicted metabolic functions. Notably, HA serves as a sustainable prebiotic substrate that supports the LGG metabolic niche and microbial homeostasis, enhances the production of SCFAs, including butyric, isobutyric, and valeric acids, and contributes to the downregulation of key osteoclastic signaling factors. Importantly, this strategy of oral SMASMs through in situ fermentation offers novel insights into addressing metabolic disorders associated with gut microbiota via the gut–X axis.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"14 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to “Aggregation-Mediated Photoacoustic/NIR-II and Photodynamic Properties of pH-Reversible Thiopyrylium Agents: A Computational and Experimental Approach” 修正“聚集介导的ph可逆硫代吡啶剂的光声/NIR-II和光动力学性质：计算和实验方法”

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-05-30 DOI: 10.1002/adma.202508839

Yishen Liu, Zhiyun Zhang, Xiaowen Hou, Qihang Ding, Silue Zeng, Hanchen Shen, Wanxia Gong, Taotao Ding, Zafar Mahmood, Xiaodong Zeng, Bingtao Ren, Wenbo Hu, Xuechuan Hong, Dan Ding, Yuling Xiao

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Robust Mix-Charged Polyzwitterionic Hydrogels for Ultra-Efficient Atmospheric Water Harvesting and Evaporative Cooling 用于超高效大气集水和蒸发冷却的强力混合荷电多两性离子水凝胶

IF 29.4 1区材料科学

Advanced Materials Pub Date : 2025-05-30 DOI: 10.1002/adma.202505279

Xuanxuan Du, Zhiheng Xie, Hanchao Zhang, Shoukun Jiang, Xing Su, Jintu Fan

{"title":"Robust Mix-Charged Polyzwitterionic Hydrogels for Ultra-Efficient Atmospheric Water Harvesting and Evaporative Cooling","authors":"Xuanxuan Du, Zhiheng Xie, Hanchao Zhang, Shoukun Jiang, Xing Su, Jintu Fan","doi":"10.1002/adma.202505279","DOIUrl":"https://doi.org/10.1002/adma.202505279","url":null,"abstract":"Atmospheric water harvesting (AWH) presents great potential in addressing the increasing global challenges in freshwater and energy supply, especially in arid and semi-arid regions. The recent AWH materials focus primarily on maximizing water uptake, while conventional approaches prioritize hygroscopicity at the expense of mechanical integrity, which severely limits their applicability in real-world scenarios. In this study, a novel tunable hygroscopic mix-charged polyzwitterionic hydrogel (THMPH) is reported that achieves dual excellence in outstanding moisture absorbency and mechanical robustness. Owing to the broad ionic crosslink's degree enabling the rigid skeletal framework and energy-dissipative sacrificial networks, THMPH exhibits more than 200 times higher mechanical ductility (225 kPa tensile strength retention at 200% mass swelling ratio) in comparison with the commonly-used AWH zwitterionic polybetaine. The optimized topological structure coupled with improved lithium chloride binding affinity results in excellent water uptake (2.9 g g−1 at 25 °C, 70% RH). When THMPH is used for daytime photovoltaic panel cooling, it can provide a 15 °C temperature reduction of a PV panel under 1 kW m−2 solar irradiation, resulting in a 7.33% increase in solar energy conversion efficiency. This hydrogel design paradigm, synergizing superior hygroscopicity with exceptional mechanical robustness, demonstrates significant potential for advancing practical applications.","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"8 1","pages":""},"PeriodicalIF":29.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0