eFood最新文献_第4页

Fungal Biomolecules for Food and Pharmaceutical Application 用于食品和制药的真菌生物分子

IF 4

eFood Pub Date : 2025-01-20 DOI: 10.1002/efd2.70033

Giancarlo Angeles Flores, Gaia Cusumano, Gokhan Zengin, Roberto Venanzoni, Paola Angelini

{"title":"Fungal Biomolecules for Food and Pharmaceutical Application","authors":"Giancarlo Angeles Flores, Gaia Cusumano, Gokhan Zengin, Roberto Venanzoni, Paola Angelini","doi":"10.1002/efd2.70033","DOIUrl":"https://doi.org/10.1002/efd2.70033","url":null,"abstract":"Mushrooms have long been an integral part of human culture and health and are valued for their nutritional and therapeutic properties. Often referred to as a superfood, mushrooms are rich in bioactive compounds that provide a range of health benefits including antioxidant, antimicrobial, anticancer, prebiotic, antidiabetic, and anti-inflammatory effects. This review focussed on the diversity of mushrooms, emphasizing their nutritional and medicinal significance, and explores their secondary metabolites with potential applications in nutraceuticals and pharmaceuticals. It underscores the role of mushrooms as vital bioactive agents in developing value-added products. An overview of the bioactive compounds, such as polysaccharides, peptides, proteins, terpenoids, and phenolic compounds, have been identified in numerous mushroom species. Additionally, the review addresses advancements in fungal biotechnology, particularly the use of fungi as efficient industrial cell factories, and their influence on food quality and sustainability. By critically analyzing recent studies, the review summarizes the diverse roles of fungal biomolecules in the food and pharmaceutical industries and highlights their significant contribution to modern medicine and health-related fields.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70033","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143117489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gut Microbiome and Tissue Morphology Modulatory Effects of Hazelnut (Natural, Roasted, and Skin) Fibers in Different Colonic Segments of Mice 榛子（天然、烘烤和皮肤）纤维对小鼠不同结肠段肠道微生物组和组织形态的调节作用

IF 4

eFood Pub Date : 2025-01-19 DOI: 10.1002/efd2.70031

Ömer F. Çelik, Elanur Daştan, Ömer F. Çetiner, Orhan Baş, Zafer Bulut, Bin Zhang, Stephen R. Lindemann, Mehmet İ. Tugay, Muhammet Değermenci, Beyza Suvarıklı-Alan, Mehmet Nizamlıoğlu, Yunus E. Tunçil

{"title":"Gut Microbiome and Tissue Morphology Modulatory Effects of Hazelnut (Natural, Roasted, and Skin) Fibers in Different Colonic Segments of Mice","authors":"Ömer F. Çelik, Elanur Daştan, Ömer F. Çetiner, Orhan Baş, Zafer Bulut, Bin Zhang, Stephen R. Lindemann, Mehmet İ. Tugay, Muhammet Değermenci, Beyza Suvarıklı-Alan, Mehmet Nizamlıoğlu, Yunus E. Tunçil","doi":"10.1002/efd2.70031","DOIUrl":"https://doi.org/10.1002/efd2.70031","url":null,"abstract":"To reveal the functional properties of hazelnut dietary fibers (DFs) in different colonic segments (cecum, proximal, and distal colon), a diet enriched with natural hazelnut, roasted hazelnut, or hazelnut skin DFs was applied to mice for 6 weeks; microbial metabolites, microbial composition, and tissue morphology were determined segmentally using gas chromatography, 16S rRNA sequencing technology, and microscopy, respectively. Roasted hazelnut DFs revealed significantly (p < 0.05) higher propionate in the cecum of female mice, while hazelnut skin DFs significantly increased the butyrate level in the distal colon of male counterparts. 16S rRNA sequencing revealed hazelnut DFs promoted the Lactobacillus animalis, L. gasseri, and Akkermansia muciniphila related OTUs, especially in the proximal colon, but the degrees of promotions were hazelnut type-, segment- and sex-dependent. Interestingly, hazelnut skin DFs significantly (p < 0.05) stimulated Prevotella related OTUs in the distal colon regardless of sex, which is known to have great ability to utilize dietary polysaccharides. Furthermore, hazelnut skin DF group had higher crypt height values, suggesting that hazelnut skin DFs have ability to maintain saccharolytic activity in more distal region of the colon. Overall, our results demonstrate that hazelnut DFs differentially impact microbial metabolite formation, microbiota composition and tissue morphology in different segments of the colon.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143117126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutrition and Dietary Pattern Associated With Chronic Obstructive Pulmonary Disease 与慢性阻塞性肺疾病相关的营养和饮食模式

IF 4

eFood Pub Date : 2025-01-06 DOI: 10.1002/efd2.70029

I-Shiang Tzeng, Wen-Lin Su, Yin-Ying Lee, Jing-Hui Wu

{"title":"Nutrition and Dietary Pattern Associated With Chronic Obstructive Pulmonary Disease","authors":"I-Shiang Tzeng, Wen-Lin Su, Yin-Ying Lee, Jing-Hui Wu","doi":"10.1002/efd2.70029","DOIUrl":"https://doi.org/10.1002/efd2.70029","url":null,"abstract":"Chronic Obstructive Pulmonary Disease (COPD) is one of the world's most significant causes of illness and mortality. It is vital to identify modifiable risk factors for COPD prevention and therapy, and the scientific community has started to focus closely on nutrition as a crucial component of COPD management, from prevention to treatment. For the progression, and management of obstructive lung illnesses like asthma and COPD, diet and nutrition may be modifiable risk factors of COPD. This review examined the connection between dietary habits, nutrient consumption, and obstructive lung disorders. Additionally, this review highlights and summarizes the evidence from observational and clinical studies regarding the influence of nutrients and dietary habits on lung function and the onset, progression, and outcomes of COPD and lung disease. Regarding the advancement or prevention of COPD, supplemental nutrition has an impact on the onset, progression, and treatment of COPD. Better pulmonary function, less deterioration in lung function, and a lower risk of COPD linked to nutraceuticals, particularly those with antioxidant and anti-inflammatory effects, when combined with balancepatterns. Health providers may use an evidence-based lifestyle approach to help counsel patients toward improved lung health if they are aware of the dietary implications of COPD.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70029","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143112646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Naturally Occurring and Artificial Nonnutritive Sweeteners: Potential Impacts on Metabolic Diseases 天然和人工非营养性甜味剂：对代谢疾病的潜在影响

IF 4

eFood Pub Date : 2025-01-06 DOI: 10.1002/efd2.70028

Yuzhuo Wang, Ligen Lin

{"title":"Naturally Occurring and Artificial Nonnutritive Sweeteners: Potential Impacts on Metabolic Diseases","authors":"Yuzhuo Wang, Ligen Lin","doi":"10.1002/efd2.70028","DOIUrl":"https://doi.org/10.1002/efd2.70028","url":null,"abstract":"Sweeteners are food additives used in processed foods and beverages, as well as health products and medicines. Due to low cost, zero calories, and intense sweetness, nonnutritive sweeteners have been widely used to replace table sugar and become the preferred strategy to manage human health. Non-nutritive sweeteners are traditionally considered to be metabolically inert, while more and more evidence indicates that they affect human health by perturbing gut microbiota and energy homeostasis. The impact of non-nutritive sweeteners on metabolic diseases still remains controversial. This review covered a total of 10 commonly used non-nutritive sweeteners, either naturally occurring or artificial, and summarized their origin, applications, and impacts on metabolic diseases, especially obesity, diabetes, and nonalcoholic fatty liver disease. The sensory assessment methods were summarized and applied to evaluate the suitability and consumer acceptance of sweeteners. The purpose of this review is to summarize the potential impacts of sweeteners on metabolic diseases, guide the safe application of sweeteners, and speculate on the future development of sweeteners.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143112645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioactive Evaluation of Naringenin in Ameliorating Hyperuricemia-Induced Liver Injury by Inhibiting Xanthine Oxidase 柚皮素通过抑制黄嘌呤氧化酶改善高尿酸血症所致肝损伤的生物活性评价

IF 4

eFood Pub Date : 2025-01-03 DOI: 10.1002/efd2.70032

Xiaoyue Zhang, Linfeng Liu, Zhaosen Fan, Nilufar Mamadalieva, Chao Liu, Xu Guo, Shutao Sun, Hui Sun, Ningyang Li, Muxuan Wang

{"title":"Bioactive Evaluation of Naringenin in Ameliorating Hyperuricemia-Induced Liver Injury by Inhibiting Xanthine Oxidase","authors":"Xiaoyue Zhang, Linfeng Liu, Zhaosen Fan, Nilufar Mamadalieva, Chao Liu, Xu Guo, Shutao Sun, Hui Sun, Ningyang Li, Muxuan Wang","doi":"10.1002/efd2.70032","DOIUrl":"https://doi.org/10.1002/efd2.70032","url":null,"abstract":"Hyperuricemia (HUA) is one of main risk factors for liver injury, and xanthine oxidase (XOD) is an important target for HUA-induced liver injury. As a typical natural active ingredient, naringenin (NAR) has been confirmed the good therapeutic effect on variety of diseases. However, studies of NAR ameliorating HUA-induced liver injury have not been reported. Therefore, we evaluated the bioactivity of NAR in ameliorating HUA-induced liver injury and investigated the related molecular mechanisms. The inhibitory activity and type of NAR on XOD was investigated by enzymatic reactions and kinetic analyses, and molecular docking showed that NAR was able to bind tightly to XOD. In vivo activity studies showed that NAR ameliorated liver function while being able to inhibit XOD activity. NAR alleviated oxidative stress in the liver caused by excess reactive oxygen species through antioxidant activity. At the same time, NAR exerted anti-inflammatory activity by regulating the levels of inflammatory factors. The molecular docking results suggested that NAR was able to interact with Keap1 and AMPK to exhibit antioxidant and anti-inflammatory effects. This work demonstrated the therapeutic effect of NAR on HUA-induced liver injury, which was valuable for the further development of related functional foods.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143111174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of a Novel Functional Solid Drink on Obesity Management and Its Underlying Mechanisms 一种新型功能性固体饮料对肥胖管理的影响及其潜在机制

IF 4

eFood Pub Date : 2025-01-03 DOI: 10.1002/efd2.70035

Ying Wen, Yan-Mei Peng, Xuan-Yu Zhou, Yu-Xin Han, Hong-Li Jiang, Hui-Xuan Wu, Yan-Hong Bu, Fei Cheng, Long Li, Fen Xiao, Jun-Min Cai, Yu-Yao Mo, Han-Dan Liang, Hou-De Zhou

{"title":"The Effect of a Novel Functional Solid Drink on Obesity Management and Its Underlying Mechanisms","authors":"Ying Wen, Yan-Mei Peng, Xuan-Yu Zhou, Yu-Xin Han, Hong-Li Jiang, Hui-Xuan Wu, Yan-Hong Bu, Fei Cheng, Long Li, Fen Xiao, Jun-Min Cai, Yu-Yao Mo, Han-Dan Liang, Hou-De Zhou","doi":"10.1002/efd2.70035","DOIUrl":"https://doi.org/10.1002/efd2.70035","url":null,"abstract":"Obesity has become a global public health concern, yet an effective, low-toxic, and high-compliance strategy for its control remains elusive. This study aims to develop a novel comprehensive intervention method for the management of obesity and its complications. Thus, we designed a functional solid beverage named RLMCR, which consists of medicinal and edible Chinese herbs. We identified its chemical composition and evaluated its efficacy. Our results indicated that RLMCR was abundant in various functional ingredients, including flavonoids, polyphenols, and terpenoids. It could mitigate lipid accumulation in 3T3-L1 cells by upregulating the expression of lipolysis-related genes. We then established diet-induced obese (DIO) mice models, which were administered with low, middle, and high doses of RLMCR for 8 weeks. Our findings indicated that the optimal dosage of RLMCR for weight loss was 3.0 g/kg, which effectively mitigated weight gain, lipid accumulation, hepatic steatosis, and abnormal glucose metabolism. Following treatment, oxygen consumption, carbon dioxide production, and thermogenesis were increased in DIO mice, without affecting food intake. The content of brown adipose tissue was significantly elevated, and the expression of thermogenesis-related genes and lipolysis-related genes in the epididymal white adipose tissue was upregulated. So, we developed a novel functional food that effectively mitigates obesity and its related metabolic disorders.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143111305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incorporating the HPLC-ESI-Q-TOF-MS profiles with the biochemical properties of eight Salvia species 采用HPLC-ESI-Q-TOF-MS图谱分析8种鼠尾草的生化特性

IF 4

eFood Pub Date : 2025-01-02 DOI: 10.1002/efd2.70021

Eulogio J. Llorent-Martínez, Nilofar, Kouadio Ibrahime Sinan, Ekrem Darendelioglu, Muammer Bahsi, Rıdvan Polat, Ugur Cakilcioglu, Giustino Orlando, Claudio Ferrante, Gokhan Zengin

{"title":"Incorporating the HPLC-ESI-Q-TOF-MS profiles with the biochemical properties of eight Salvia species","authors":"Eulogio J. Llorent-Martínez,  Nilofar, Kouadio Ibrahime Sinan, Ekrem Darendelioglu, Muammer Bahsi, Rıdvan Polat, Ugur Cakilcioglu, Giustino Orlando, Claudio Ferrante, Gokhan Zengin","doi":"10.1002/efd2.70021","DOIUrl":"https://doi.org/10.1002/efd2.70021","url":null,"abstract":"Salvia, a widely recognized genus globally esteemed for its traditional and medicinal applications, prompted our investigation into the methanol and water extracts of eight Salvia species native to Turkey. These species included S. aucheri, S. candidissima, S. divaricata, S. virgata, S. multicaulis, S. palestina, S. trichoclada, and S. cerino-pruinosa. Our study aimed to assess their biological properties and chemical composition. Utilizing HPLC-ESI-Q-TOF-MS, we identified chemical constituents in the extracts, while antioxidant (radical quenching, reducing power, and metal chelating) and enzyme inhibitory (amylase, glucosidase, tyrosinase, and cholinesterase) activities were evaluated for biological activities. One hundred thirty-one compounds were characterized in the tested extracts. Although many compounds belonging to different chemical families were identified, the main compounds in all the extracts were rosmarinic and sagerinic acids, along with several salvianolic acid isomers. Notably, the methanol extracts displayed superior antioxidant properties overall, with S. cerino-pruinosa exhibiting the highest activity among them, except for metal chelating. Similar to the antioxidant test results, the methanol extracts were more active than the water extracts in the enzyme inhibition tests. Multivariate analysis further highlighted the distinctiveness of the water extract of S. cerino-pruinosa. In conclusion, our findings underscore the biopharmaceutical potential of the tested Salvia species, suggesting their significance as sources of bioactive agents for health-promoting applications.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143110824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the Protective Mechanisms of Chayote (Sechium edule) Juice in Mitigating Streptozotocin-Induced Pancreatic Dysfunction 探讨佛手瓜汁减轻链脲佐菌素诱导的胰腺功能障碍的保护机制

IF 4

eFood Pub Date : 2024-12-29 DOI: 10.1002/efd2.70036

Yoon A. Jeon, Premkumar Natraj, Soo-Heui Paik, Seong Cheol Kim, Young Jae Lee

{"title":"Exploring the Protective Mechanisms of Chayote (Sechium edule) Juice in Mitigating Streptozotocin-Induced Pancreatic Dysfunction","authors":"Yoon A. Jeon, Premkumar Natraj, Soo-Heui Paik, Seong Cheol Kim, Young Jae Lee","doi":"10.1002/efd2.70036","DOIUrl":"https://doi.org/10.1002/efd2.70036","url":null,"abstract":"Chayote (Sechium edule) has been traditionally used in Mexico to manage diabetes, owing to its hypoglycemic, anti-oxidant, and anti-inflammatory properties. However, the specific effects and mechanisms of chayote juice (SEJ) in preventing pancreatic dysfunction remain underexplored. This study investigated the pancreatic protective effects and underlying mechanisms of SEJ in multiple low-dose streptozotocin (MLD-STZ)-induced diabetic mouse model and H2O2-treated mouse insulinoma cell line (MIN-6). C57BL/6 mice were administered MLD-STZ to induce pancreatic dysfunction and treated with SEJ. Diabetic parameters, pancreatic islet morphology, and protein expressions were evaluated. H2O2-treated MIN-6 cells were used to assess SEJ's protective mechanisms at the cellular level. Molecular docking studies were performed to elucidate interactions between SEJ phenolic compounds and key proteins involved in oxidative stress. SEJ significantly preserved pancreatic islet structure and insulin levels, reducing blood glucose levels. Mechanistically, SEJ suppressed the expression of apoptosis markers (caspase-3, PARP, BAX) and inflammatory markers (NF-κB, iNOS, NLRP3) in the pancreas and MIN6 cells, indicating protection of the pancreas and β-cells. Furthermore, SEJ upregulates endogenous anti-oxidant proteins (Nrf-2, HO-1), which are essential for mitigating oxidative stress-induced cell stress in diabetes circumstances. Molecular docking indicated that vicenin-2 in SEJ exhibit strong binding affinities to KEAP-1, Nrf-2, and HO-1 proteins. SEJ demonstrates substantial pancreatic protective effects through its anti-oxidant, anti-apoptotic, and anti-inflammatory actions. These findings suggest that chayote juice could be developed as a functional food for diabetes management.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2024-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70036","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143120402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tea Tree Oil Delays Kiwifruit Ripening Through Regulating Energy Metabolism 茶树油通过调节能量代谢延缓猕猴桃成熟

IF 4

eFood Pub Date : 2024-12-24 DOI: 10.1002/efd2.70030

Changchun Fu, Shiyan Zhu, Ying Ni, Hangjun Chen, Yanchao Han

{"title":"Tea Tree Oil Delays Kiwifruit Ripening Through Regulating Energy Metabolism","authors":"Changchun Fu, Shiyan Zhu, Ying Ni, Hangjun Chen, Yanchao Han","doi":"10.1002/efd2.70030","DOIUrl":"https://doi.org/10.1002/efd2.70030","url":null,"abstract":"Kiwifruit is easy to ripen and soften after harvest. Tea tree oil (TTO) has important application value in postharvest fruit preservation. However, the effect of TTO on kiwifruit fruit ripening, quality maintenance and energy metabolism, has not been studied. In this research, we found that TTO could delay ‘Xuxiang’ kiwifruit ripening, and keep good quality even after 18 days of storage. In three different concentrations of TTO treatments, 2.0 mL L−1 TTO has the best preservation effect on kiwifruit. TTO slowed down the softening and degreening, reduced the respiration intensity and delayed the peak of respiration. Moreover, TTO also delayed the decrease of total sugar, titratable acid (TA) and vitamin C (Vc). The fruit treated with TTO kept higher levels of ATP, ADP and energy charge (EC), and higher activities of succinate dehydrogenase (SDH), cytochrome C oxidase (CCO) and ATPase. Correlation analysis results showed that kiwifruit ripening was closely related to nutritional quality and energy metabolism. To summarize, TTO could delay kiwifruit ripening and keep fruit quality by maintaining higher energy level and activities of energy metabolism-related enzymes during the late storage. This study will provide theoretical and technical support for kiwifruit preservation.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143118803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The stability and bioavailability of xanthohumol loaded by sophorolipid-based microemulsions in functional beer 苦参脂微乳负载黄腐酚在功能性啤酒中的稳定性和生物利用度

IF 4

eFood Pub Date : 2024-12-18 DOI: 10.1002/efd2.161

Qiannan Pan, Cheng Chen, Jingyang Luo, Weisu Huang, Yuhang Zhu, Kejie Peng, Zefeng Guo, Baiyi Lu

{"title":"The stability and bioavailability of xanthohumol loaded by sophorolipid-based microemulsions in functional beer","authors":"Qiannan Pan, Cheng Chen, Jingyang Luo, Weisu Huang, Yuhang Zhu, Kejie Peng, Zefeng Guo, Baiyi Lu","doi":"10.1002/efd2.161","DOIUrl":"https://doi.org/10.1002/efd2.161","url":null,"abstract":"Xanthohumol (XN) exhibits numerous physiological activities, yet its instability and proneness to degradation limit its use. Microemulsions, noted for effective drug solubilization and delivery, have been employed to enhance XN's stability and bioavailability in functional beers, using sophorolipids (SL) and Tween 80 (T80) as surfactants. Our development of T80-ME and T80-SL-ME stabilized XN, as confirmed by reduced degradation in high-performance liquid chromatography analysis and kinetic modeling. We established in vitro release and in vivo pharmacokinetic models, demonstrating improved outcomes with XN-enriched beer. Our study also assessed total phenols, flavonoids, and antiaging effects in the beer. The formulation minimally affected beer's physicochemical properties, including pH, turbidity, and bitterness. Notably, XN's bioavailability in beer improved 1.79- to 7.33-fold, underscoring microemulsion technology's role in enhancing XN absorption and metabolism. We analyzed the sensory flavor impact of SL biosurfactants in beer, finding them acceptable to consumers. This study highlights microemulsions' potential in elevating functional beer's nutritive value and applications.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.161","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142861663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0