IF 5.7

eFood Pub Date : 2025-07-18 DOI: 10.1002/efd2.70083

Tsung-Han Lu, Szu-Yu Kuo, Jui-Hsia Hsu, Yen-Lien Chen, Han-Hsin Chang, Chin-Chu Chen, David Pei-Cheng Lin

{"title":"Utilizing Cordyceps cicadae Mycelium as a Potential Supplement for Alleviating UVB-Induced Photokeratitis Symptoms In Vivo","authors":"Tsung-Han Lu, Szu-Yu Kuo, Jui-Hsia Hsu, Yen-Lien Chen, Han-Hsin Chang, Chin-Chu Chen, David Pei-Cheng Lin","doi":"10.1002/efd2.70083","DOIUrl":"10.1002/efd2.70083","url":null,"abstract":"Ultraviolet (UV) radiation exposure to the cornea can lead to photokeratitis, disrupting tear film homeostasis and increasing the risk of dry eye disease (DED). While Cordyceps cicadae mycelium extracts (CCME) have been reported to benefit ocular diseases, their potential to alleviate UVB-induced photokeratitis remains unexplored. This study investigated the CCME's protective effects against UVB-induced corneal damage. ICR mice were randomly assigned to three groups: a control group, a UVB-exposed group with vehicle treatment (UVB group), and a UVB-exposed group treated with CCME (CCME group). Tear volume (TV), tear break-up time (TBUT), ocular surface integrity, conjunctival goblet cell density, and inflammatory markers were evaluated. The results demonstrated that CCME intake significantly improved TV and TBUT, while reducing oxidative stress and inflammatory markers (p63 + , PCNA, NF-κB, and COX-2). Notably, CCME treatment helped to preserve goblet cells and maintain Muc5Ac expression therein, with concomitant suppression on lipid peroxidation (as indicated by MDA and 4-HNE reduction) in the meibomian glands, suggesting its role in stabilizing tear film composition. This study advances the field by introducing CCME as a potential therapeutic agent for photokeratitis, offering a natural, oral treatment alternative with anti-inflammatory and antioxidative properties. CCME could help prevent progression to chronic DED and other ocular surface disorders by mitigating corneal inflammation and preserving tear film components. Given the elevated prevalence of UV-induced ocular damage due to environmental changes, these findings provide a foundation for developing CCME-based interventions in ophthalmology, bridging traditional medicine with modern therapeutic interventions.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 4","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70083","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144647081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laxative Effect of Lactobacillus paracasei Glory LP16 on Loperamide-Induced Constipation in Mice 副干酪乳杆菌LP16对洛哌丁胺致小鼠便秘的通便作用

IF 5.7

eFood Pub Date : 2025-07-14 DOI: 10.1002/efd2.70068

Weiwei Ma, Lian Lian, Lidong Guo, Yanan Wu, Lili Huang

{"title":"Laxative Effect of Lactobacillus paracasei Glory LP16 on Loperamide-Induced Constipation in Mice","authors":"Weiwei Ma, Lian Lian, Lidong Guo, Yanan Wu, Lili Huang","doi":"10.1002/efd2.70068","DOIUrl":"10.1002/efd2.70068","url":null,"abstract":"Constipation is a common gastrointestinal disease. In recent years, probiotic intervention has often been used to solve such problems. However, the results of existing studies on different intervention times and dose differences are not consistent. Therefore, it is necessary to conduct research on specific strains. In this study, loperamide was used to establish the constipation model. By observing the basic fecal parameters, gastrointestinal characteristics, histological morphology, short-chain fatty acids, and microbiota composition of constipated mice, the remission mechanisms of different doses of Lactobacillus paracasei Glory LP16 (LP16) on constipated mice were compared. It was found that different doses of LP16 could improve gastrointestinal peristalsis and neurotransmitter levels in constipated mice, reduce intestinal inflammation, significantly increase the concentration of short-chain fatty acids, and improve the intestinal flora. Macrogenomics indicates that LP16 is mainly enriched in metabolic pathways such as amino acid biosynthesis and amino acid and nucleotide sugar metabolism. The expression of glycoside hydrolase in mice increased significantly. The results show that LP16 has laxative and antidiarrheal effects. Its laxative and antidiarrheal mechanisms may be related to its effects on constipation-related neurotransmitters, improving intestinal flora, increasing fecal acetic acid content in constipated mice, and alleviating constipation-induced inflammation.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 4","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144615306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fucoidan From Brown Algae as a Functional Food Ingredient: A Promising Anticancer Agent 褐藻褐藻聚糖作为功能性食品成分：一种有前景的抗癌剂

IF 5.7

eFood Pub Date : 2025-07-14 DOI: 10.1002/efd2.70085

Muhammad Umer Khan, Iqra Khurram, Maha Munir, Muhammad Ikram Ullah, Heba Bassiony Ghanem, Javad Sharifi-Rad, William N. Setzer, Daniela Calina

{"title":"Fucoidan From Brown Algae as a Functional Food Ingredient: A Promising Anticancer Agent","authors":"Muhammad Umer Khan, Iqra Khurram, Maha Munir, Muhammad Ikram Ullah, Heba Bassiony Ghanem, Javad Sharifi-Rad, William N. Setzer, Daniela Calina","doi":"10.1002/efd2.70085","DOIUrl":"10.1002/efd2.70085","url":null,"abstract":"Fucoidan is a naturally occurring, sulfated fucose-based polymer found in many types of brown algae. Fucoidan has recently attracted interest in the field of oncology due to its biological and pharmacological features, such as antitumor, anti-proliferation, and anti-inflammatory effects. Fucoidan's attributes are mostly determined by its relative molecular mass and the processes of purification and extraction, which result in structural modifications and can alter outcomes. Several in vivo and in vitro research are being conducted to investigate fucoidan's anticancer potential so that it can be employed as a therapeutic agent; also, decreased toxicity and in vitro impacts of fucoidan make it feasible for cancer therapy. The current review will summarize various aspects of fucoidan including the source and structural activity of fucoidan along with the anticancer relationship of fucoidan on multiple cell lines. In this review, the bioavailability and pharmacological properties are also discussed along with the mechanism of action through which fucoidan inhibits proliferation or induces apoptosis in different tumors, suggesting it is a potential therapeutic agent for combating various tumors.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 4","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70085","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144615205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rosa roxburghii Tratt Fruit Juice Ameliorates DSS-Induced Colitis by Improving Intestinal Barrier and Gut Microbiota Independently of Vitamin C 刺梨果汁通过改善肠道屏障和独立于维生素C的肠道微生物群来改善dss诱导的结肠炎

IF 5.7

eFood Pub Date : 2025-07-14 DOI: 10.1002/efd2.70084

Wenyue Chen, Dafeng Fang, Lili Zhang, Mingqing Kuang, Mengyao Zhang, Chenxiao Shen, Yi Liu, Hefeng Zhou, Shengpeng Wang, Wenwen Zhao, Yitao Wang, Zhangfeng Zhong

{"title":"Rosa roxburghii Tratt Fruit Juice Ameliorates DSS-Induced Colitis by Improving Intestinal Barrier and Gut Microbiota Independently of Vitamin C","authors":"Wenyue Chen, Dafeng Fang, Lili Zhang, Mingqing Kuang, Mengyao Zhang, Chenxiao Shen, Yi Liu, Hefeng Zhou, Shengpeng Wang, Wenwen Zhao, Yitao Wang, Zhangfeng Zhong","doi":"10.1002/efd2.70084","DOIUrl":"10.1002/efd2.70084","url":null,"abstract":"Rosa roxburghii Tratt (Cili) is a vitamin C-rich fruit with bioactive polyphenols and flavonoids. This study explored the components of Cili fruit juice and investigated its therapeutic potential in a dextran sodium sulfate (DSS)-induced ulcerative colitis (UC) murine model. Our results revealed that Cili fruit juice and its components (vitamin C and kajiichigaside F1) significantly alleviated colitis symptoms. Notably, colitis symptoms improved even when vitamin C-deficient Cili juice was administered. Specifically, Cili fruit juice restored intestinal barrier integrity, regulated inflammatory cytokines (TNF-α, IL-6, IL-8, and IL-12), and modulated gut microbiota dysbiosis by rebalancing Epsilonbacteraeota, Proteobacteria, and Lactobacillus abundances. Furthermore, Cili fruit juice positively modulated cellular metabolic processes and inflammatory pathways. These findings identify Cili fruit juice as a promising natural adjuvant therapy for UC, driven by the potent bioactivity of kajiichigaside F1, offering a novel strategy to enhance intestinal homeostasis and mitigate inflammation.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 4","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70084","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144615307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Millet Bran Bound Phenolic Compounds Suppresses LPS-Induced Inflammatory Response in Macrophages and Liver Injury Mice via TLR4/NF-κB Signaling Pathway 谷糠结合酚类化合物通过TLR4/NF-κB信号通路抑制lps诱导的巨噬细胞和肝损伤小鼠炎症反应

IF 5.7

eFood Pub Date : 2025-07-09 DOI: 10.1002/efd2.70078

Ying-kun Cai, Jin-yue Sun, Ying-ying Chen, Meng-qi Zhang, Shu-tao Sun, Qi-dong Ren, Mu-xuan Wang, Mohamed A. Farag, Bo Zhang, Xu Guo, Chao Liu

{"title":"Millet Bran Bound Phenolic Compounds Suppresses LPS-Induced Inflammatory Response in Macrophages and Liver Injury Mice via TLR4/NF-κB Signaling Pathway","authors":"Ying-kun Cai, Jin-yue Sun, Ying-ying Chen, Meng-qi Zhang, Shu-tao Sun, Qi-dong Ren, Mu-xuan Wang, Mohamed A. Farag, Bo Zhang, Xu Guo, Chao Liu","doi":"10.1002/efd2.70078","DOIUrl":"10.1002/efd2.70078","url":null,"abstract":"Millet bran, rich in bioactive phenolic compounds, holds potential for both nutritional and therapeutic applications. In this study, bound phenolic compounds were isolated from millet bran, yielding a potent fraction named BPS-2. UPLC-MS/MS detected 16 major phenolic compounds in BPS-2. In vitro assays revealed that BPS-2 exerted a significant anti-inflammatory activity in lipopolysaccharide (LPS)-induced RAW 264.7 macrophage, as manifested by reduced production of inflammatory mediators (IL-1β, IL-6, and TNF-α) and downregulation of the expression levels of the pro-inflammatory enzymes Cyclooxygenase-2 (COX-2) and nitric oxide synthase (iNOS). Network pharmacological analysis identified the suppression of the TLR4/NF-κB pathway as the primary mechanism mediating the anti-inflammatory activity of BPS-2, which was validated using the LPS-induced RAW 264.7 macrophage model and liver injury mice model. Western blot analysis revealed that BPS-2 significantly decreased the phosphorylation of IκBα and p65 to regulate the TLR4/NF-κB signaling pathway, thereby exerting anti-inflammatory activity. Molecular docking studies revealed strong interactions between the active compounds of BPS-2 and TLR4 through key amino acid residues, including Pro116, Thr114, and Arg105. These results underscore the potential application of millet bran bound phenolic compounds as naturally occurring anti-inflammatory substances.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 4","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70078","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics Analysis and Intestinal Effects of Probiotic-Derived Nano-Selenium by Lactobacillus bulgaricus CICC 20247 保加利亚乳杆菌CICC 20247益生菌源纳米硒的特性分析及肠道效应

IF 5.7

eFood Pub Date : 2025-07-09 DOI: 10.1002/efd2.70074

Yebo Wang, Ke Li, Wenting Zhu, Huijuan Xi, Meng Qi, Ping Chen, Hanyu Chen, Chun-e Zhang, Ying Luo

{"title":"Characteristics Analysis and Intestinal Effects of Probiotic-Derived Nano-Selenium by Lactobacillus bulgaricus CICC 20247","authors":"Yebo Wang, Ke Li, Wenting Zhu, Huijuan Xi, Meng Qi, Ping Chen, Hanyu Chen, Chun-e Zhang, Ying Luo","doi":"10.1002/efd2.70074","DOIUrl":"10.1002/efd2.70074","url":null,"abstract":"The bioproduction of selenium nanoparticles (SeNPs) is garnering increasing attention as an environmentally friendly method, given that many microorganisms inherently possess the ability to synthesize nano-selenium. In the present study, Lactobacillus bulgaricus (L. bulgaricus) was selected to convert sodium selenite to SeNPs, the optimum conversion conditions were finally established, the morphology and structure of SeNPs were characterized as uniform distribution spherical particles with average size of 92.4 nm, in combination with field emission scanning electron microscope (FE-SEM), transmission electron microscope (TEM), X-ray photoelectron spectroscopy (XPS), and Fourier transform infrared spectroscopy (FTIR). 16S rDNA sequencing and genomic sequencing revealed that SeNPs influenced the composition of the gut microbiota, the abilities of immune and metabolism in mice were improved significantly after SeNPs supplement. The results corroborated the potential of SeNPs synthesized from probiotic L. bulgaricus CICC 20247 in intestinal health promotion and various biomedical even food processing applications.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 4","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70074","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacterial Nanocellulose: A Sustainable Revolution in Food Science 细菌纳米纤维素：食品科学的可持续革命

IF 5.7

eFood Pub Date : 2025-07-09 DOI: 10.1002/efd2.70080

Masoud Aman Mohammadi, Adel Mirza Alizadeh, Samira Dakhili, Safa Kooki, Seyede Marzieh Hosseini

{"title":"Bacterial Nanocellulose: A Sustainable Revolution in Food Science","authors":"Masoud Aman Mohammadi, Adel Mirza Alizadeh, Samira Dakhili, Safa Kooki, Seyede Marzieh Hosseini","doi":"10.1002/efd2.70080","DOIUrl":"10.1002/efd2.70080","url":null,"abstract":"Bacterial nanocellulose (BNC) is an eco-friendly biomaterial celebrated for its exceptional physicochemical properties, making it valuable across diverse industries. Produced through bacterial fermentation, BNC exhibits high mechanical strength, biocompatibility, and biodegradability, ideal for applications in biomedicine, environmental remediation, and food science. In the food sector, BNC serves as a sustainable alternative to synthetic additives and packaging. It functions as a thickening, stabilizing, and gelling agent, improving texture, consistency, and shelf life in products like sauces, dairy, and gluten-free baked goods. Additionally, BNC's role as an edible coating and biodegradable packaging material offers innovative solutions for food preservation, reducing spoilage, and addressing plastic waste concerns. This review outlines BNC's production processes, emphasizing bacterial strain selection, culture media optimization, and fermentation control. It also highlights its multifaceted applications in enhancing food safety, packaging, and quality. Despite challenges such as high production costs, scalability issues, and regulatory compliance, future directions, including genetically engineered BNC, nanocomposites, and smart technology integration, suggest promising advancements. BNC is poised to transform food production and packaging by fostering more sustainable, innovative practices.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 4","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70080","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Methodological Review of Strategies for Artificial Contamination of Solid Food With Aspergillus flavus and Aflatoxin B1: Insights Into Growth Dynamics, AFB1 Production, and Spiking Techniques for Cereals, Nuts, and Seeds 人造固体食品黄曲霉和黄曲霉毒素B1污染策略的方法学综述：对谷物、坚果和种子生长动力学、AFB1生产和穗化技术的见解

IF 5.7

eFood Pub Date : 2025-07-09 DOI: 10.1002/efd2.70082

Alaa Abou Dib, Nicolas Louka, Jean Claude Assaf, Sami El Khatib, André El Khoury, Espérance Debs

{"title":"A Methodological Review of Strategies for Artificial Contamination of Solid Food With Aspergillus flavus and Aflatoxin B1: Insights Into Growth Dynamics, AFB1 Production, and Spiking Techniques for Cereals, Nuts, and Seeds","authors":"Alaa Abou Dib, Nicolas Louka, Jean Claude Assaf, Sami El Khatib, André El Khoury, Espérance Debs","doi":"10.1002/efd2.70082","DOIUrl":"10.1002/efd2.70082","url":null,"abstract":"Aspergillus flavus (A. flavus), is a prevalent contaminant of solid food and feed. It produces aflatoxin B1 (AFB1) and B2 (AFB2) posing significant toxicological risks to both humans and animals. Extensive research has been conducted to develop reliable methods for AFB1 detection, A. flavus control, and AFB1 reduction. However, these methods require consistent sampling of contaminated cereals, nuts, or seeds. Yet, naturally contaminated samples often pose challenges due to nonhomogeneous mold distribution, co-infection by other fungal genera, and multi-mycotoxin contamination. Therefore, researchers often rely on artificially contaminated samples to ensure accurate and reproducible results. Artificial contamination can be achieved either by inoculating A. flavus spores allowing in situ AFB1 production under optimal conditions or by spiking grains or kernels with AFB1. The objective of this review is to report protocols for artificially contaminating solid food, beginning with an overview of the morphology and life cycle of A. flavus. It critically analyzes methods used for contaminating cereals, nuts, and seeds, with attention to pretreatment procedures, experimental steps, and optimal growth conditions for A. flavus and AFB1 production. It is intended as a comprehensive reference in the matter, providing essential information for preparing representative samples of artificially contaminated food with A. flavus or AFB1.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 4","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70082","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144589702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AI-Powered Advancements in Food Analysis and Safety: Ensuring Quality, Protection, and Precision in Modern Food Systems: A Review 人工智能在食品分析和安全方面的进步：确保现代食品系统的质量、保护和精度：综述

IF 5.7

eFood Pub Date : 2025-07-04 DOI: 10.1002/efd2.70076

Ammar B. Altemimi, Farhang Hameed Awlqadr, Raqad R. Al-Hatim, Syamand Ahmed Qadir, Mohammed N. Saeed, Aryan Mahmood Faraj, Tablo H. Salih, Hala S. Mahmood, Mohammad Ali Hesarinejad, Francesco Cacciola

{"title":"AI-Powered Advancements in Food Analysis and Safety: Ensuring Quality, Protection, and Precision in Modern Food Systems: A Review","authors":"Ammar B. Altemimi, Farhang Hameed Awlqadr, Raqad R. Al-Hatim, Syamand Ahmed Qadir, Mohammed N. Saeed, Aryan Mahmood Faraj, Tablo H. Salih, Hala S. Mahmood, Mohammad Ali Hesarinejad, Francesco Cacciola","doi":"10.1002/efd2.70076","DOIUrl":"10.1002/efd2.70076","url":null,"abstract":"The review paper is about the amazing influence that artificial intelligence (AI) has brought to the food production industry, as it gives much importance to food safety and quality assurance. It introduces the connection of AI technologies, including machine learning, deep learning, and computer vision, to enhancing food safety, control, and analysis. The role of AI in contaminant detection and spoilage prediction is underlined. One of the applications is using near-infrared spectroscopy on a machine learning algorithm sample to determine if it contains any adulterants in olive oil. Also, trying to develop computer vision techniques that can soon be widely deployed to detect defects in the automated visual inspection of produce. Real-time monitoring sensors incorporated in smart packaging solutions are among the AI that protects and manages the freshness and safety of perishable goods. The review, through analyzing up-to-date AI techniques in the food sector, also proposes potential remedies to the ongoing food issues that can lead to unhealthy and unsafe products. Furthermore, it sheds light on AI's role in food science and its function as a safeguarding agent of the youth sector in the food industry.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 4","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70076","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioactive Compounds, Their Mechanisms of Action, and Cardioprotective Effects of Pomegranate (Punica granatum): A Comprehensive Review 石榴（Punica granatum）的生物活性化合物、作用机制和心脏保护作用综述

IF 5.7

eFood Pub Date : 2025-07-01 DOI: 10.1002/efd2.70075

Esha Saeed, Farah Javed, Zoya Rana, Rashida Perveen, Iftikhar Younis Mallhi, Izza Amjad, Quratulain Maqsood, Nauman Ali Chaudhary, Saleha Binte Tahir, Arooj Fatima, Noor Fatima Rasheed, Esther Ugo Alum

{"title":"Bioactive Compounds, Their Mechanisms of Action, and Cardioprotective Effects of Pomegranate (Punica granatum): A Comprehensive Review","authors":"Esha Saeed, Farah Javed, Zoya Rana, Rashida Perveen, Iftikhar Younis Mallhi, Izza Amjad, Quratulain Maqsood, Nauman Ali Chaudhary, Saleha Binte Tahir, Arooj Fatima, Noor Fatima Rasheed, Esther Ugo Alum","doi":"10.1002/efd2.70075","DOIUrl":"10.1002/efd2.70075","url":null,"abstract":"Pomegranate (Punica granatum L.) is a nutritionally dense fruit containing antioxidants and bioactive compounds, demonstrating significant potential in preventing and managing cardiovascular diseases (CVDs). This review evaluates the vasculoprotective effects of various pomegranate components, including the fruit arils, seeds, peel, and flower extracts. The arils and seeds are abundant in anthocyanins, ellagic acid, and polyphenols, while the peel and flower extracts contain high concentrations of punicalagin, gallic acid, and other potent polyphenols. Human and animal studies have consistently demonstrated that pomegranate consumption can lower blood pressure, improve lipid profiles, and reduce inflammation. Researchers found that daily consumption of should be 50–240 mL of pomegranate juice, 1–1.5 g of peel extract, or 200–500 mg of standardized flower extract. However, due to the high natural sugar content of pomegranate juice and its potential to interact with certain medications, moderate consumption is advised. Overall, pomegranate represents a promising nonpharmacological adjunct in CVD prevention. Further research is needed to optimize its use for maximum cardiovascular benefits. This review highlights pomegranate's potential as a valuable, nonpharmaceutical resource for supporting cardiovascular health.","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 4","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70075","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144519960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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