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Assessment of Metabolome Variation in Field-Grown Lettuce in Context to Its Different Types and Soil Types as Analyzed via GC-MS Analysis and Using of Chemometric Tools 利用气相色谱-质谱分析和化学计量学工具分析了不同类型和土壤类型下大田生菜代谢组的变化
IF 4
eFood Pub Date : 2025-03-13 DOI: 10.1002/efd2.70049
Mostafa H. Baky, Sally E. Khaled, Mohamed R. Khalifa, Mohamed A. Farag
{"title":"Assessment of Metabolome Variation in Field-Grown Lettuce in Context to Its Different Types and Soil Types as Analyzed via GC-MS Analysis and Using of Chemometric Tools","authors":"Mostafa H. Baky,&nbsp;Sally E. Khaled,&nbsp;Mohamed R. Khalifa,&nbsp;Mohamed A. Farag","doi":"10.1002/efd2.70049","DOIUrl":"https://doi.org/10.1002/efd2.70049","url":null,"abstract":"<p>Lettuce (<i>Lactuca sativa</i> L.) is one of the most important ready-to-eat vegetables widely consumed worldwide owing to its nutritional and health benefits. A total of 111 peaks were identified via gas chromatography-mass spectrometry (GC-MS) with sugars represented the most abundant primary metabolite class detected in lettuce specially in sandy soil grown lettuce compared to that in mud soil. The highest sugar level was detected in iceberg lettuce grown in sand soil at 967.1 mg/g versus lowest in “Baladi” lettuce grown in mud soil at 48.2 mg/g. Glucose represented the major sugar at 733.4 mg in iceberg grown in sand soil (SC) compared to 94.7 mg/g in that grown in muddy soil (MC). Sucrose detected at 212-434 mg/g compared to traces in samples grown in muddy soil (MB and MC). Higher levels of amino acids were detected in green leaf lettuce in sandy soil (SC) at 130 mg/g, with L-proline as the major amino form. Iceberg lettuce grown in SC was discriminated from other samples with the aid of chemometric analysis due to its richness in sugars, while green leaf lettuce in SC was discriminated by its richness in amino acids, organic acids, and sugar alcohols.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biodegradation of T-2 Toxin by a Dominant Microbial Consortium Isolated From Chinese Yeast Ball 酵母球中优势菌群对T-2毒素的降解研究
IF 4
eFood Pub Date : 2025-03-12 DOI: 10.1002/efd2.70047
Chun-Ming Yang, Norlia Mahror, Shao-Ji Li, Lu Liu, Lai-Hoong Cheng
{"title":"Biodegradation of T-2 Toxin by a Dominant Microbial Consortium Isolated From Chinese Yeast Ball","authors":"Chun-Ming Yang,&nbsp;Norlia Mahror,&nbsp;Shao-Ji Li,&nbsp;Lu Liu,&nbsp;Lai-Hoong Cheng","doi":"10.1002/efd2.70047","DOIUrl":"https://doi.org/10.1002/efd2.70047","url":null,"abstract":"<p>T-2 toxin is a highly toxic type A trichothecene mycotoxin commonly found in feed, agricultural products like wheat, corn, and barley, as well as processed foods, presenting substantial health hazards to both humans and animals. In this study, a microbial consortium (designated as BJ) with stable and efficient T-2 toxin degradation activity was isolated from Chinese yeast balls, a traditional Chinese fermentation starter. The consortium was dominated by species of <i>Wickerhamomyces</i>, <i>Pichia</i>, and <i>Pediococcus</i>. This BJ consortium demonstrated the ability to degrade 99.2% of the T-2 toxin to HT-2 toxin, T-2 triol, and T-2 tetraol within 48 h, outperforming individual strains. Metagenomic sequencing and LC-MS/MS metabolic analysis elucidated the degradation pathway, which includes deacetylation and de-epoxidation of the epoxy group, with the cytochrome P450 enzyme CYP61 in <i>Wickerhamomyces ciferrii</i> playing a key role in detoxification. The study highlights the potential of the BJ consortium as a natural agent for T-2 toxin detoxification in the feed and food industry, though further research is warranted to assess its real-world application and safety.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolomics and Microbiomics Perspectives Reveal the Regulatory Pathways of Monaphilone B Derived From Red Yeast Rice on Alcoholic Liver Injury in Mice 代谢组学和微生物学视角揭示红曲米单胞菌素B对小鼠酒精性肝损伤的调控途径
IF 4
eFood Pub Date : 2025-03-12 DOI: 10.1002/efd2.70048
Li Wu, Zihua Liang, Ziyi Yang, Hao Wang, Li Ni, Weiling Guo, Xucong Lv
{"title":"Metabolomics and Microbiomics Perspectives Reveal the Regulatory Pathways of Monaphilone B Derived From Red Yeast Rice on Alcoholic Liver Injury in Mice","authors":"Li Wu,&nbsp;Zihua Liang,&nbsp;Ziyi Yang,&nbsp;Hao Wang,&nbsp;Li Ni,&nbsp;Weiling Guo,&nbsp;Xucong Lv","doi":"10.1002/efd2.70048","DOIUrl":"https://doi.org/10.1002/efd2.70048","url":null,"abstract":"<p>Red yeast rice (RYR) has been extensively used as a natural food for thousands of years and still plays an important role in the world food industry. In this study, the protective effect and the mechanism of monaphilone B (MB) from RYR on alcoholic liver injury were investigated in mice. The results showed that MB effectively ameliorated alcohol-induced liver lipid metabolism (decreasing serum total cholesterol [TC], triglyceride [TG], low-density lipoprotein cholesterol [LDL-C], and increasing high-density lipoprotein cholesterol [HDL-C]), oxidative stress (decreasing hepatic maleic dialdehyde [MDA] level, increasing catalase [CAT], superoxide dismutase [SOD], alcohol dehydrogenase [ADH] and glutathione [GSH] hepatic activities), and inflammatory response (decreasing hepatic lipopolysaccharide [LPS], tumor necrosis factor-α [TNF-α], Interferon-γ [IFN-γ] and interleukin 6 [IL-6]), repaired liver function (reducing serum alanine aminotransferase [ALT], aspartate aminotransferase [AST], and liver lactate dehydrogenase [LDH] activity). 16S amplicon sequencing showed that MB administration effectively modulated intestinal flora and its metabolism, which were highly correlated with the improvement of liver function and intestinal barrier function. Liver metabolomics analysis indicated that MB administration regulated 69 liver potential biomarkers involved in glycerophospholipid metabolism, nicotinate and nicotinamide metabolism, tryptophan metabolism, and so on. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and Western blot (WB) analysis revealed that MB administration modulated gene transcription and protein expression related to liver lipid metabolism and oxidative stress. These findings provide scientific evidence that MB has the biological activity to ameliorate alcohol-induced lipid metabolism disorders, liver oxidative stress, and enterobacterial dysbiosis.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70048","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Metabolomic Analysis of Phenolic Compounds in Different Ramulus Mori (Sangzhi) Based on UPLC-ESI-MS/MS 基于 UPLC-ESI-MS/MS 的不同桑枝中酚类化合物的代谢组学比较分析
IF 4
eFood Pub Date : 2025-03-11 DOI: 10.1002/efd2.70046
Yi Wang, Sheng Zhou, Chenlei Li, Yuyi Shen, Zhenjiang Wang, Xiaojie Yan, Wenkui Dai
{"title":"Comparative Metabolomic Analysis of Phenolic Compounds in Different Ramulus Mori (Sangzhi) Based on UPLC-ESI-MS/MS","authors":"Yi Wang,&nbsp;Sheng Zhou,&nbsp;Chenlei Li,&nbsp;Yuyi Shen,&nbsp;Zhenjiang Wang,&nbsp;Xiaojie Yan,&nbsp;Wenkui Dai","doi":"10.1002/efd2.70046","DOIUrl":"https://doi.org/10.1002/efd2.70046","url":null,"abstract":"<p>In traditional Chinese medicine, Ramulus mori (Sangzhi) is used to lower blood sugar and treat diseases such as diabetes, and its therapeutic effects are attributed to an abundance of bioactive compounds. This study employed a comparative analysis of Ramulus mori (Sangzhi) from three geographical regions within China. The samples included <i>Morus atropurpurea</i> Roxb from Guangdong (GDS), <i>Morus australis</i> Poir from Jiangsu (JS), and <i>Morus nigra</i> Linn, which is native to Xinjiang (XJYS). The study discovered significant differences in total polyphenol and flavonoid content among various Ramulus mori (Sangzhi), with those from XJYS showing the highest levels. Utilizing UPLC-ESI-MS/MS technology, a total of 128 phenolic metabolites were identified, from which 17 differential metabolites were screened. In Comparison to GDS, JS, and XJYS exhibited 12 and 10 different metabolites, respectively, with 8 differential metabolites observed between JS and XJYS. Furthermore, XJYS exhibited a higher polyphenol and flavonoid content than the other two varieties. Additionally, some of the upregulated differential metabolites have been confirmed to possess a variety of pharmacological effects and health benefits. Kyoto Encyclopedia of Genes and Genomes analysis linked these to flavonoid biosynthesis, and qRT-PCR confirmed corresponding gene expression patterns. These findings provided a theoretical basis for the use of Ramulus mori (Sangzhi) in the pharmaceutical and food industries.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of Guaiacol Production With Presence and Expression of the Guaiacol Biosynthetic Gene Cluster in Alicyclobacillus Spp 银环杆菌愈创木酚合成基因簇的存在与表达与愈创木酚产量的关系
IF 4
eFood Pub Date : 2025-03-04 DOI: 10.1002/efd2.70045
Rui Cai, Yanhui Li, Qi Wang, Hong Guo, Yuxiang Zhang, Yahong Yuan, Qinglin Sheng, Zhouli Wang, Tianli Yue
{"title":"Correlation of Guaiacol Production With Presence and Expression of the Guaiacol Biosynthetic Gene Cluster in Alicyclobacillus Spp","authors":"Rui Cai,&nbsp;Yanhui Li,&nbsp;Qi Wang,&nbsp;Hong Guo,&nbsp;Yuxiang Zhang,&nbsp;Yahong Yuan,&nbsp;Qinglin Sheng,&nbsp;Zhouli Wang,&nbsp;Tianli Yue","doi":"10.1002/efd2.70045","DOIUrl":"https://doi.org/10.1002/efd2.70045","url":null,"abstract":"<p>The whole genome sequences of <i>A. dauci</i> DSM 28700, <i>A. fastidiosus</i> KKP 3000 (guaiacol producers), and <i>A. fastidiosus</i> DSM 17978 (non-guaiacol producer) were firstly determined. Then, the presence of the guaiacol biosynthetic gene cluster in genome sequences of 7 guaiacol-producing and 16 non-guaiacol producing <i>Alicyclobacillus</i> strains was explored. Of the 7 <i>Alicyclobacillus</i> guaiacol producers investigated, a complete guaiacol biosynthetic gene cluster was found in <i>A. fastidiosus</i> K3000, <i>A. acidiphilus</i> NBRC 100859, <i>A. dauci</i> DSM 28700, <i>A. suci</i> VF-FSL-W10-0049 and FSL-W10-0048; only <i>guaB</i>, <i>guaC</i>, <i>guaD</i>, and <i>guaE</i> genes were found in <i>A. herbarius</i> DSM 13609, and <i>guaA</i>, <i>guaB</i>, <i>guaC</i>, <i>guaD</i>, and <i>guaE</i> genes were found in <i>A. hesperidum</i> subsp. <i>aegles</i> DSM 11985. There was no complete guaiacol gene cluster present in the tested 16 <i>Alicyclobacillus</i> non-guaiacol producers. The expression kinetics of genes in the guaiacol biosynthetic gene cluster under the conditions of producing and not producing guaiacol indicated that the expression of the 6 genes was closely related to the production of guaiacol in <i>A. acidoterrestris</i>. These findings will facilitate a deeper understanding of guaiacol production in <i>Alicyclobacillus</i> spp., which will contribute to develop effective control methods to minimize <i>Alicyclobacillus</i>-related spoilage in the fruit juice industry.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70045","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143535989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Ochratoxin A Reduction and Physicochemical Properties of Green Coffee Beans Following Atmospheric Nonthermal Plasma and Plasma-Activated Water Treatments 常压非热等离子体和等离子体活化水处理后绿咖啡豆赭曲霉毒素A还原及理化性质的评价
IF 4
eFood Pub Date : 2025-03-02 DOI: 10.1002/efd2.70040
Ashrie Yacab, Chia-Min Lin, Pei-Shan Chih, Trias Mahmudiono, Chih-Yao Hou, Hsiu-Ling Chen
{"title":"Evaluation of the Ochratoxin A Reduction and Physicochemical Properties of Green Coffee Beans Following Atmospheric Nonthermal Plasma and Plasma-Activated Water Treatments","authors":"Ashrie Yacab,&nbsp;Chia-Min Lin,&nbsp;Pei-Shan Chih,&nbsp;Trias Mahmudiono,&nbsp;Chih-Yao Hou,&nbsp;Hsiu-Ling Chen","doi":"10.1002/efd2.70040","DOIUrl":"https://doi.org/10.1002/efd2.70040","url":null,"abstract":"<p>Nonthermal plasma (NTP) is a novel nonthermal technology with many potential applications in the food industry because of its promising effects on food decontamination, including mycotoxin decontamination. In this study, atmospheric NTP and plasma-activated water (PAW) were used to evaluate ochratoxin A (OTA) reduction and the quality of green coffee beans. Artificially contaminated green coffee beans were subjected to atmospheric NTP, PAW, atmospheric NTP-PAW, and PAW-atmospheric NTP treatments for 2 min, and OTA was then analyzed using liquid chromatography with tandem mass spectrometry before and after each treatment. NTP-based treatments significantly reduced OTA concentration in green coffee beans by 37.66%–51.80%. The maximum reduction efficiency was found in PAW-atmospheric NTP treatment. Furthermore, no negative effects were observed in terms of color, caffeine content, total phenolic content, total flavonoid content, and DPPH scavenging activity, except for atmospheric NTP treatment, which exhibited distinct color changes. In addition, a minimal decrease in the aroma of green coffee beans was observed following atmospheric NTP and PAW treatments, whereas a minimal increase was observed when both treatments were combined. NTP-based treatments provide new approaches for mitigating mycotoxin in the food industry as well as important implications for the use of atmospheric NTP and PAW in the coffee industry.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Bibliometric Analysis of Research Conducted in the Past 118 Years on Global Prospective, Scientific Mapping, and Emerging Trends in Wild Fruits 过去118年来关于野生水果全球前景、科学制图和新兴趋势研究的文献计量学分析
IF 4
eFood Pub Date : 2025-02-27 DOI: 10.1002/efd2.70037
Baby Gargi, Sakshi Painuli, Prateek Gururani, Prabhakar Semwal, Sanjay Kumar
{"title":"A Bibliometric Analysis of Research Conducted in the Past 118 Years on Global Prospective, Scientific Mapping, and Emerging Trends in Wild Fruits","authors":"Baby Gargi,&nbsp;Sakshi Painuli,&nbsp;Prateek Gururani,&nbsp;Prabhakar Semwal,&nbsp;Sanjay Kumar","doi":"10.1002/efd2.70037","DOIUrl":"https://doi.org/10.1002/efd2.70037","url":null,"abstract":"<p>Wild edible fruits, commonly referred to as “hidden treasures,” hold a plethora of valuable resources. These fruits have the potential to significantly contribute to the provision of a proportionate and nutritious diet, particularly in impoverished areas across the globe. Despite this, these resources are still underutilized, primarily due to their declining availability and alterations in lifestyle patterns. A bibliometric analysis covering the past 118 years of existence has been conducted to assess the current state of trends, gaps, and research directions in wild fruit research to identify the global research output in this area. In recent years, there has been a substantial increase in research interest towards the growing conservation and domestication of wild fruits, specifically to address the risk of hunger and undernourishment. The quantity of articles has consistently increased since the identification of a significant peak in 2020. However, advanced scientific investigations on appropriate species are recommended to determine the potential species that could alter, augment, or be used as a substitute for the domesticated species in terms of their chemical and nutritional content. In addition, collaboration among various research communities and government or nongovernment organizations is suggested to determine the application of wild fruits in addressing the food security concerns for the increasing global population.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70037","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143513703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel deproteinization method from crude polysaccharides of Meretrix meretrix Linnaeus based on palygorskite-chitosan composite aerogel sieving effect 基于壳聚糖-壳聚糖复合气凝胶筛分效应的锦葵粗多糖脱蛋白新方法
IF 4
eFood Pub Date : 2025-02-23 DOI: 10.1002/efd2.70014
Yong Zhu, Jingrui Ma, Xinhang Li, Quanrun He, Bingmin Wu, Juanjuan Cheng, Song Huang, Jihang Chen
{"title":"A novel deproteinization method from crude polysaccharides of Meretrix meretrix Linnaeus based on palygorskite-chitosan composite aerogel sieving effect","authors":"Yong Zhu,&nbsp;Jingrui Ma,&nbsp;Xinhang Li,&nbsp;Quanrun He,&nbsp;Bingmin Wu,&nbsp;Juanjuan Cheng,&nbsp;Song Huang,&nbsp;Jihang Chen","doi":"10.1002/efd2.70014","DOIUrl":"https://doi.org/10.1002/efd2.70014","url":null,"abstract":"<p>Due to the delicious taste and remarkable bioactivities of <i>Meretrix meretrix</i> L., they have garnered attention in food field. However, the challenge arises when attempting to separate proteins from crude polysaccharides with similar polarity and solubility. This paper aimed to develop a novel deproteinization method from crude polysaccharides of <i>Meretrix meretrix</i> L. (CPM) based on palygorskite-chitosan composite aerogel (Pal-CS aerogel) sieving effect. We focused on the influence of aerogels' pore structure on the selective deproteinization of CPM. In comparison to palygorskite or chitosan, Pal-CS aerogel exhibited a superior advantage in selectively deproteinization due to its unique pore structure. Furthermore, under the concentration conditions of 2% Pal and 0.8% CS, the deproteinization rate (<i>Dr</i>%), polysaccharide adsorption rate (<i>Pr</i>%) and selectivity coefficient (<i>Kc</i>) reached impressive values of 95.08 ± 1.47%, 3.29 ± 0.14% and 28.95 ± 0.82, respectively. The findings from pore size analysis revealed that an appropriate size ranging from 0.1 μm to 3.0 μm significantly contributed to the selectively deproteinization based on the sieving effect. The adsorption mechanism study further highlighted that hydrogen bonding predominantly dominated the interfacial interaction between aerogel and proteins. In conclusion, this work provided a new perspective for the study on deproteinization of food polysaccharides.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143475459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intake of High-Calorie Diet and Phytonutrients: A New Paradigm to Treat Cerebral Palsy in Children 高热量饮食和植物营养素的摄入:治疗儿童脑瘫的新模式
IF 4
eFood Pub Date : 2025-02-12 DOI: 10.1002/efd2.70042
Tabussam Tufail, Huma Bader Ul Ain,  Mahwish, Sana Noreen, Aiman Ijaz, Ali Ikram, Muhammad Tayyab Arshad, Muhammed Adem Abdullahi
{"title":"Intake of High-Calorie Diet and Phytonutrients: A New Paradigm to Treat Cerebral Palsy in Children","authors":"Tabussam Tufail,&nbsp;Huma Bader Ul Ain,&nbsp; Mahwish,&nbsp;Sana Noreen,&nbsp;Aiman Ijaz,&nbsp;Ali Ikram,&nbsp;Muhammad Tayyab Arshad,&nbsp;Muhammed Adem Abdullahi","doi":"10.1002/efd2.70042","DOIUrl":"https://doi.org/10.1002/efd2.70042","url":null,"abstract":"<p>Cerebral palsy (CP) encompasses neurodevelopmental disorders affecting movement and posture, arising from nonprogressive brain damage during prenatal, perinatal, or postnatal periods. Diagnosis typically occurs between ages 3 and 5, with symptoms including abnormal muscle tone and impaired motor skills. CP's etiology is diverse, ranging from genetic predispositions to perinatal complications, often exacerbated by poor nutrition. Management requires a multidisciplinary approach involving neurologists, therapists, surgeons, psychologists, and social workers to address motor impairments and co-morbidities like epilepsy, cognitive deficits, and sensory impairments. Neurological rehabilitation, primarily through physical and occupational therapies, forms the cornerstone of CP management. Addressing feeding difficulties, common in CP, often necessitates enteral or parenteral feeding, each with potential complications. High-calorie formulas offer a promising strategy to combat undernutrition and improve motor outcomes. Research also explores the potential benefits of natural compounds like kaempferol and resveratrol, though further investigation is needed.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comprehensive Review on Health Benefits of Fructooligosaccharides 低聚果糖的健康益处综述
IF 4
eFood Pub Date : 2025-02-12 DOI: 10.1002/efd2.70041
Asia Atta, Sumaira Sharif, Kainat Haroon, Musarrat Rasheed, Soumya V. Menon, Jadhav Balaji, Bhavik Jain, Qaswaa Yousif Jameel, Mohd Asif Shah
{"title":"A Comprehensive Review on Health Benefits of Fructooligosaccharides","authors":"Asia Atta,&nbsp;Sumaira Sharif,&nbsp;Kainat Haroon,&nbsp;Musarrat Rasheed,&nbsp;Soumya V. Menon,&nbsp;Jadhav Balaji,&nbsp;Bhavik Jain,&nbsp;Qaswaa Yousif Jameel,&nbsp;Mohd Asif Shah","doi":"10.1002/efd2.70041","DOIUrl":"https://doi.org/10.1002/efd2.70041","url":null,"abstract":"<p>Short-chain carbohydrates are primarily made up of fructose molecules; fructooligosaccharides (FOS) are referred to as prebiotics and are renowned for their potential beneficial effects on health. Since they are inedible fibers, FOS go through the upper digestive tract nearly undisturbed while entering the colon, where they offer food to beneficial gut bacteria, such as <i>Lactobacilli</i> and <i>Bifidobacteria</i>. This method supports digestive health and improves immunity by maintaining an optimal gut microbiome. Based on studies, through establishing an optimal gut environment, FOS can reduce the risk of several digestive disorders, particularly inflammatory bowel disease (IBD), constipation, and irritable bowel syndrome (IBS). FOS has shown potential for improving metabolic health along with digestive health. They can help regulate weight and reduce the risk of diabetes due to their low caloric content and ability to regulate blood glucose levels. This review will contribute to the development of more focused and effective applications of FOS in health and medicine by identifying the areas of research gaps and suggesting future directions.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":"6 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.70041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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