Early Intervention in Psychiatry最新文献

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Exploring Behavioural Patterns in Youth Predisposed to Bipolar Disorder and the Role of Interpersonal Trauma Using the Adolescent Brain Cognitive Development (ABCD) Dataset 利用青少年大脑认知发展(ABCD)数据集探索易患双相情感障碍的青少年行为模式和人际创伤的作用
IF 2.1 4区 医学
Early Intervention in Psychiatry Pub Date : 2025-05-30 DOI: 10.1111/eip.70058
Christina Ghaleb, Danielle Penney, Katie M. Lavigne, Delphine Raucher-Chéné
{"title":"Exploring Behavioural Patterns in Youth Predisposed to Bipolar Disorder and the Role of Interpersonal Trauma Using the Adolescent Brain Cognitive Development (ABCD) Dataset","authors":"Christina Ghaleb,&nbsp;Danielle Penney,&nbsp;Katie M. Lavigne,&nbsp;Delphine Raucher-Chéné","doi":"10.1111/eip.70058","DOIUrl":"https://doi.org/10.1111/eip.70058","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Bipolar disorder (BD) is a severe, persistent disorder that causes functional impairment. Besides heritability, environmental factors, such as traumatic experience, impact the development of BD. Little is known about the early developmental signs of this disorder; therefore, this study aims to look at the impact of interpersonal trauma on the early developmental signs of BD. Specifically, differences in psychopathological behaviours were investigated between (1) at-risk children and controls and (2) at-risk children who experienced an interpersonal traumatic event and those who did not.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using the Adolescent Brain Cognitive Development (ABCD) dataset, participants with a first-degree relative with BD were identified (<i>N</i><sub>at-risk</sub> = 625) and matched on sex and age to a control group (<i>N</i><sub>control</sub> = 625). The Kiddie Schedule for Affective Disorders and Schizophrenia (KSADS) was used to assess interpersonal trauma and psychopathological symptoms. The trauma (<i>N</i><sub>trauma</sub> = 198) and no-trauma sub-groups (<i>N</i><sub>no-trauma</sub> = 428) were built from the at-risk population. Group comparison was conducted on depressive, manic and anxiety symptoms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Compared to controls, at-risk children exhibited a significantly greater number of manic symptoms at baseline and 2-year follow-up, and anxiety symptoms at follow-up. No significant differences were found between the trauma and no-trauma groups at either baseline or follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>These results confirm the presence of early symptoms in at-risk children, in line with the staging model of BD. Extended longitudinal research is needed to further investigate the potential specific role of trauma on its early behavioural patterns.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70058","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of an Online Mental Health Website for the Early Intervention in Psychosis Services, Developed for the Early Youth Engagement (EYE-2) Trial: A Cross-Sectional Survey Study of Clinical Barriers and Facilitators to Normalisation 精神病服务早期干预的在线心理健康网站的实施,为早期青少年参与(EYE-2)试验开发:临床障碍和正常化促进因素的横断面调查研究
IF 2.1 4区 医学
Early Intervention in Psychiatry Pub Date : 2025-05-29 DOI: 10.1111/eip.70055
Elizabeth Robson, Kathryn Greenwood
{"title":"Implementation of an Online Mental Health Website for the Early Intervention in Psychosis Services, Developed for the Early Youth Engagement (EYE-2) Trial: A Cross-Sectional Survey Study of Clinical Barriers and Facilitators to Normalisation","authors":"Elizabeth Robson,&nbsp;Kathryn Greenwood","doi":"10.1111/eip.70055","DOIUrl":"https://doi.org/10.1111/eip.70055","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Disengagement is a problem for early intervention in psychosis (EIP) services. Access to trusted information on a website might help to overcome some of the problems associated with disengagement. Clinician and organisational engagement are integral to the implementation and uptake of online resources.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims and Objectives</h3>\u0000 \u0000 <p>A theory-driven approach used the normalisation process theory (NPT) to investigate the implementation of an NHS psychoeducational website developed for the Early Youth Engagement Project (EYE-2). The aim was to establish barriers and facilitators to website use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cross-sectional survey study was used; 36 EIP clinicians in Sussex were asked about their attitudes towards introducing the website and using it in appointments. Accessibility, usability and internet skills were also measured.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A key implementation barrier was lack of familiarity with the website and its content, which inhibited use. Poorer scores in the NPT ‘Collective Action’ construct relating to Skillset Workability and Relational Integration (staff confidence and ability) suggested that clinicians lacked confidence in their skills and ability to introduce the website in clinical sessions. Findings suggest that clinicians, might have lower operational skills compared to the general population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Embedding of nominated digital leads in teams as well as appropriate training is required to promote familiarity, confidence and enhance digital skills. Larger studies are required to establish the replicability of our findings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70055","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sun Exposure and Anorexia Nervosa: A Potential Environmental–Biological Interaction? 日晒与神经性厌食症:潜在的环境-生物相互作用?
IF 2.1 4区 医学
Early Intervention in Psychiatry Pub Date : 2025-05-27 DOI: 10.1111/eip.70054
Andrea Phillipou
{"title":"Sun Exposure and Anorexia Nervosa: A Potential Environmental–Biological Interaction?","authors":"Andrea Phillipou","doi":"10.1111/eip.70054","DOIUrl":"https://doi.org/10.1111/eip.70054","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Despite first being described in 1888, anorexia nervosa continues to be the deadliest of all psychiatric illnesses. Although efforts have been made to elucidate the aetiological factors involved in the illness, little progress has been made in uncovering what contributes to the development and maintenance of anorexia nervosa. A particular shortcoming of the current literature has been the investigation of interactions between environmental and biological factors. One such interaction which has yet to receive attention in anorexia nervosa is that of sun exposure. Exposure to the sun—including levels of ultraviolet radiation (UVR) and vitamin D—in the pathogenesis of other mental illnesses has long been investigated (with lower levels of vitamin D reportedly involved in the pathogenesis of conditions such as schizophrenia, for example) but is yet to be explored in anorexia nervosa.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The current paper proposes a novel hypothesis for the potential contribution of reduced sun exposure in the aetiology of anorexia nervosa for future investigation, and possible mechanisms for how this relationship may operate.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70054","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Duration of Untreated Bipolar Disorder on Clinical Outcomes: A Systematic Review 未治疗双相情感障碍持续时间对临床结果的影响:一项系统综述
IF 2.1 4区 医学
Early Intervention in Psychiatry Pub Date : 2025-05-27 DOI: 10.1111/eip.70059
Sara Ahmadieh Mena, Norma Verdolini, Salvador Miret, Nuria Laherrán, Samuel Pàmpols, Roberto Palacios-Garrán
{"title":"Impact of Duration of Untreated Bipolar Disorder on Clinical Outcomes: A Systematic Review","authors":"Sara Ahmadieh Mena,&nbsp;Norma Verdolini,&nbsp;Salvador Miret,&nbsp;Nuria Laherrán,&nbsp;Samuel Pàmpols,&nbsp;Roberto Palacios-Garrán","doi":"10.1111/eip.70059","DOIUrl":"https://doi.org/10.1111/eip.70059","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Bipolar disorder (BD) prognosis is influenced by multiple factors, including age, sex and comorbid conditions. This review focuses on the concept termed ‘duration of untreated bipolar disorder’ (DUB), defined as the interval between the onset of affective symptoms and the initiation of appropriate treatment. This variable may significantly influence the course and recovery of individuals with BD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The main objective is to determine whether an association exists between DUB and clinical outcomes in patients with BD, and to examine the potential implications of reducing DUB on the long-term prognosis of the disorder.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic literature search was conducted using MeSH descriptors across the PubMed, Scopus, and Cochrane Library databases. A total of 1573 articles were initially identified. Following a rigorous screening and eligibility assessment process, a total of 15 articles met the inclusion criteria and were included in this review. The results obtained have been systematically analysed and synthesised for further evaluation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A prolonged DUB was associated with several clinical variables, including BD II, a longer duration of the illness, early age of onset, first episode of depressive polarity, higher number of depressive episodes and higher number of suicide attempts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Limitations</h3>\u0000 \u0000 <p>There is currently no consensus on the definition or standardised measurement of DUB, which limits comparability across studies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>DUB appears to be a modifiable factor associated with poorer clinical outcomes in BD patients. Reducing DUB may improve long-term management of BD. Tailored early treatment strategies might be implemented to address this.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations Between Childhood Trauma and Social Cognition in Early Psychosis 儿童创伤与早期精神病患者社会认知的关系
IF 2.1 4区 医学
Early Intervention in Psychiatry Pub Date : 2025-05-12 DOI: 10.1111/eip.70052
D. Cavero, R. Jenni, P. Golay, M. Gorgellino, P. Klauser, M. Cleusix, L. Abrahamyan Empson, T. Petrova, I. Lepreux, C. Conchon, P. Conus, C. L. Lam, L. Alameda
{"title":"Associations Between Childhood Trauma and Social Cognition in Early Psychosis","authors":"D. Cavero,&nbsp;R. Jenni,&nbsp;P. Golay,&nbsp;M. Gorgellino,&nbsp;P. Klauser,&nbsp;M. Cleusix,&nbsp;L. Abrahamyan Empson,&nbsp;T. Petrova,&nbsp;I. Lepreux,&nbsp;C. Conchon,&nbsp;P. Conus,&nbsp;C. L. Lam,&nbsp;L. Alameda","doi":"10.1111/eip.70052","DOIUrl":"https://doi.org/10.1111/eip.70052","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Childhood trauma (CT), in the form of abuse and neglect, and altered social cognition (SC) are both linked to poorer clinical and functional outcomes in psychosis. The impact of CT and its subtypes on SC in early psychosis has been underexplored, with mixed findings from previous studies. The current study investigated the effects of CT and its subtypes on SC in at-risk mental state (ARMS) for psychosis and first episode psychosis (FEP) individuals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>One hundred and seventeen individuals were included (ARMS [<i>n</i> = 51], FEP [<i>n</i> = 66]). History of CT was assessed using the composite score of the Childhood Trauma Questionnaire. SC abilities were tested with the Reading the Mind in the Eyes Test for Theory of Mind (ToM) and Emotion Expression Multimorph Task for Emotion Recognition (ER). Linear regression, ANCOVA, and repeated-measures ANOVA were performed to investigate main and interaction effects.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>FEP individuals performed significantly worse than ARMS participants in ER sensitivity. Composite CT was not associated with SC in either cohort. Physical neglect was a strong predictor of poorer ToM in FEP individuals (<span></span><math>\u0000 <semantics>\u0000 <mrow>\u0000 <msup>\u0000 <mi>η</mi>\u0000 <mn>2</mn>\u0000 </msup>\u0000 </mrow>\u0000 <annotation>$$ {eta}^2 $$</annotation>\u0000 </semantics></math> = 0.082). Physical abuse was negatively associated with overall ER sensitivity in ARMS participants versus FEPs (<span></span><math>\u0000 <semantics>\u0000 <mrow>\u0000 <msubsup>\u0000 <mi>η</mi>\u0000 <mi>p</mi>\u0000 <mn>2</mn>\u0000 </msubsup>\u0000 </mrow>\u0000 <annotation>$$ {eta}_p^2 $$</annotation>\u0000 </semantics></math> = 0.079), particularly anger (<i>p</i> &lt; 0.001), disgust (<i>p</i> = 0.019), and sadness (<i>p</i> = 0.004).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Results highlight the importance of investigating effects of CT subtypes on SC performance in early psychosis as specific subtypes may impact differentially on SC. These associations can guide further investigation of underlying mechanisms and inform personalised interventions for early psychosis targeting specific SC deficits linked to CT in future research.</p>\u0000 </section>\u0000 <","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143939007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uncertainty Mentalizing and Emotion Dysregulation With Substance Use Severity in Iranian Young Adults; Mediating Role of Borderline Personality Traits 伊朗青少年物质使用严重程度的不确定性心理和情绪失调边缘型人格特质的中介作用
IF 2.1 4区 医学
Early Intervention in Psychiatry Pub Date : 2025-05-08 DOI: 10.1111/eip.70040
Mehdi Azad, Farhad Taremian, Shima Shakiba
{"title":"Uncertainty Mentalizing and Emotion Dysregulation With Substance Use Severity in Iranian Young Adults; Mediating Role of Borderline Personality Traits","authors":"Mehdi Azad,&nbsp;Farhad Taremian,&nbsp;Shima Shakiba","doi":"10.1111/eip.70040","DOIUrl":"https://doi.org/10.1111/eip.70040","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The rising prevalence of substance use amongst young people (ages 18–25) is a critical global health issue, especially in non-Western contexts where cultural factors impact mental health. This study explores the role of uncertainty mentalizing—understanding ambiguous social situations—in individuals with borderline personality traits and its link to substance use, a relationship that remains underexplored amongst young Iranian people. It further examines the mediating role of borderline personality traits in the relationship between uncertainty mentalizing, emotion dysregulation and substance use severity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>The study included 185 people who use substances aged 18–25 years who completed questionnaires related to the research variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Analysis Revealed Significant Positive Associations Amongst all Variables (<i>p</i> &lt; 0.001). Borderline Personality Traits (<i>β</i> = 0.19, <i>p</i> &lt; 0.05) and Uncertainty Mentalizing (<i>β</i> = 0.45, <i>p</i> &lt; 0.001) Directly Influenced Substance Use Severity. Uncertainty Mentalizing Also Indirectly Affected Substance Use Severity Through Borderline Personality Traits (Indirect Effect = 0.093, <i>p</i> &lt; 0.05) and Notably Impacted Borderline Personality Traits (<i>β</i> = 0.49, <i>p</i> &lt; 0.001). However, Emotion Dysregulation Did Not Show Significant Direct or Indirect Effects.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>These results highlight the critical role of uncertainty mentalizing in substance use severity, both directly and through its influence on borderline personality traits, suggesting that interventions aimed at enhancing uncertainty mentalizing may effectively address co-occurring issues related to substance use and borderline personality traits.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mental Health of Indian Transgender Individuals: A Meta-Ethnography 印度跨性别者的心理健康:元民族志
IF 2.1 4区 医学
Early Intervention in Psychiatry Pub Date : 2025-05-02 DOI: 10.1111/eip.70048
Kumari Sarika, Devu Rajeev, Sucharita Maji, Gerald Jordan
{"title":"Mental Health of Indian Transgender Individuals: A Meta-Ethnography","authors":"Kumari Sarika,&nbsp;Devu Rajeev,&nbsp;Sucharita Maji,&nbsp;Gerald Jordan","doi":"10.1111/eip.70048","DOIUrl":"https://doi.org/10.1111/eip.70048","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Gender, as a social determinant of health, places transgender (TG) individuals at increased risk for mental health issues. This review aimed to explore the mental health challenges faced by Indian transgender individuals and the factors contributing to these challenges through an interpretative synthesis of existing qualitative research.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A meta-ethnographic approach was used to synthesise qualitative research on the mental health of transgender individuals in India. Ten studies were systematically identified, reviewed and analysed using Noblit and Hare's method (1988) of meta-ethnography.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Four major themes emerged from the synthesis: healthcare barriers, predisposing factors to psychological distress, mental health issues, and coping strategies. Within healthcare barriers, three sub-themes were identified: stigma and discrimination within the healthcare system, limited life resources for accessing services, and healthcare-system barriers. Predisposing factors emerged at micro (individual and familial), meso (community and organisational) and macro (societal and legal) levels, reflecting varied sources of distress. Mental health issues such as anxiety, depression, suicidality and substance use were reported.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Based on these findings, a model is developed to illustrate the interconnected factors affecting the mental health of Indian transgender individuals. The findings have important implications for improving healthcare, policy and mental health practices to better support transgender individuals.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143897224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increased Prevalence of Childhood Complex Trauma in Comorbid Posttraumatic Stress Disorder and Substance Use Disorders Compared to Either Disorder Alone: A Systematic Review 与单独的创伤后应激障碍和物质使用障碍相比,合并创伤后应激障碍和物质使用障碍的儿童复杂创伤患病率增加:一项系统综述
IF 2.1 4区 医学
Early Intervention in Psychiatry Pub Date : 2025-05-02 DOI: 10.1111/eip.70051
Herry Patel, Bethany Easterbrook, Fiona A. Ralston, Daria Shariff, Haley Lester, Daniel Landaverde, Erika Lau, Isabella S. Davis, Isabel R. Aks, Sandra A. Brown, Susan F. Tapert, William E. Pelham III
{"title":"Increased Prevalence of Childhood Complex Trauma in Comorbid Posttraumatic Stress Disorder and Substance Use Disorders Compared to Either Disorder Alone: A Systematic Review","authors":"Herry Patel,&nbsp;Bethany Easterbrook,&nbsp;Fiona A. Ralston,&nbsp;Daria Shariff,&nbsp;Haley Lester,&nbsp;Daniel Landaverde,&nbsp;Erika Lau,&nbsp;Isabella S. Davis,&nbsp;Isabel R. Aks,&nbsp;Sandra A. Brown,&nbsp;Susan F. Tapert,&nbsp;William E. Pelham III","doi":"10.1111/eip.70051","DOIUrl":"https://doi.org/10.1111/eip.70051","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Childhood complex trauma (CCT) prevalence among individuals with comorbid posttraumatic stress disorder (PTSD) and substance use disorder (SUD) is unknown. We conducted a meta-analysis to compare CCT prevalence in samples of PTSD alone, SUD alone and comorbid PTSD+SUD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A systematic review of PTSD, CCT and SUD literature was conducted using online databases. Binary outcome meta-analytic models were fitted comparing CCT prevalence in comorbid PTSD + SUD to PTSD and SUD only.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Seven studies were included, and estimates for CCT prevalence were higher, on average, among individuals with comorbid PTSD+SUD (35%–78%) compared to PTSD alone (4%–70%) and SUD alone (2%–65%). A meta-analysis of four studies indicated individuals with comorbid PTSD+SUD were 18% more likely to have experienced CCT compared to individuals with PTSD only (RR = 1.18, 95% CI [1.13, 1.25]) and 24% more likely compared to individuals with SUD only (RR = 1.24, 95% CI [1.20, 1.29]).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Further research is needed to establish a more accurate prevalence rate for individuals with comorbid PTSD and SUD. Evidence of greater CCT prevalence will inform research study design and clinical targets during treatment for individuals with comorbid PTSD and SUD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility of a School-Based Suicide Prevention Gatekeeper Intervention and an Implementation Intervention (Project ROS): Study Protocol 基于学校的自杀预防看门人干预和实施干预的可行性(项目ROS):研究方案
IF 2.1 4区 医学
Early Intervention in Psychiatry Pub Date : 2025-05-01 DOI: 10.1111/eip.70050
Lena Rossen Østergaard, Lotus Sofie Bast, Rory C. O'Connor, Erik Christiansen
{"title":"Feasibility of a School-Based Suicide Prevention Gatekeeper Intervention and an Implementation Intervention (Project ROS): Study Protocol","authors":"Lena Rossen Østergaard,&nbsp;Lotus Sofie Bast,&nbsp;Rory C. O'Connor,&nbsp;Erik Christiansen","doi":"10.1111/eip.70050","DOIUrl":"https://doi.org/10.1111/eip.70050","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Despite the high risk of suicidal behaviour in youth, there is a lack of evidence-based interventions within school settings for those who are at increased risk. The Project ROS (in Realise, Convince and Refer in Danish Realiser, Overbevis og Send videre) will train teaching staff and implement QPR (Question, Persuade, Refer), a suicide prevention gatekeeper intervention supported by an implementation intervention at specialised schools (FGU) in Denmark.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To determine the feasibility of delivering school-based QPR (Question, Persuade, Refer) gatekeeper training, supported by an implementation intervention based on evidence-based implementation strategies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A two-phase case study with a feasibility hybrid evaluation design. The evaluation will include a multimethod approach including pre-, post- and follow-up survey measurements, field observations and semi-structured single and focus group interviews.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>A multimethod design will be used to validate the results. The use of methodological triangulation will help to reduce bias and deficiencies compared to using a single-method design.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143896939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing Role Functioning in Clinical High Risk for Psychosis: An Open Trial of “InVEST” (Individualised Vocational and Educational Support and Training) 增强精神病临床高危人群的角色功能:InVEST"(个性化职业和教育支持与培训)公开试验
IF 2.1 4区 医学
Early Intervention in Psychiatry Pub Date : 2025-04-22 DOI: 10.1111/eip.70041
Michelle L. West, Julia Pfluger, Shadi Sharif, Claire Goods, Michelle Friedman-Yakoobian
{"title":"Enhancing Role Functioning in Clinical High Risk for Psychosis: An Open Trial of “InVEST” (Individualised Vocational and Educational Support and Training)","authors":"Michelle L. West,&nbsp;Julia Pfluger,&nbsp;Shadi Sharif,&nbsp;Claire Goods,&nbsp;Michelle Friedman-Yakoobian","doi":"10.1111/eip.70041","DOIUrl":"https://doi.org/10.1111/eip.70041","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>School and vocational (“role”) functioning is an important treatment target for young people exhibiting signs of clinical high risk for psychosis (CHR-P). However, there are currently no evidence-based approaches to help people at CHR-P with role functioning difficulties.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This manuscript describes the development and pilot open trial evaluation of “InVEST” (Individualised Vocational and Educational Support and Training). InVEST is a coaching program designed to enhance role functioning in youth at CHR-P. InVEST is designed to be flexible, low-intensity, and easy-to-train, and it is carried out by bachelor's and undergraduate-level “coaches” who work with clients individually for 4 months. The intervention specifically targets three mechanisms believed to relate to role functioning in this clinical population: (1) organisation, (2) task initiation, and (3) distress resilience. This manuscript describes a small open trial and the iterative development of a manual based on participant feedback about this intervention in preparation for a randomised controlled trial.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All participants (<i>N</i> = 5) completed the baseline assessment, 16 weeks of coaching, and follow-up, with no dropouts. Participants reported high satisfaction with the program, and participant feedback was used to iterate and develop the InVEST manual. Additionally, most participants showed improvement in role functioning (4/5), organisation and planning (4/5), and task initiation (3/5) following InVEST participation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This small pilot study provides initial support for the feasibility and acceptability of InVEST and suggests that further study in comparison to a control condition is warranted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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